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|id=CL:0000451
|id=CL:0000451
|name=dendritic cell
|name=dendritic cell
|namespace=cell
|namespace=efo
|def="A cell of hematopoietic origin, typically resident in particular tissues, specialized in the uptake, processing, and transport of antigens to lymph nodes for the purpose of stimulating an immune response via T cell activation. These cells are lineage negative (CD3-negative, CD19-negative, CD34-negative, and CD56-negative)." [GOC:add, ISBN:0781735149]
|def="A cell of hematopoietic origin, typically resident in particular tissues, specialized in the uptake, processing, and transport of antigens to lymph nodes for the purpose of stimulating an immune response via T cell activation. These cells are lineage negative (CD3-negative, CD19-negative, CD34-negative, and CD56-negative)." [GOC:add, ISBN:0781735149]
|xref=BTO:0002042;;FMA:83036
|xref=BTO:0002042;;FMA:83036
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|located_in=
|located_in=
|part_of=
|part_of=
|property_value=IAO:0000412 http://purl.obolibrary.org/obo/cl.owl;;IAO:0000412 http://purl.obolibrary.org/obo/efo.obo.owl
|is_obsolete=
|preceded_by=
}}
}}

Revision as of 17:37, 15 June 2012

Name:dendritic cell
Namespace:efo
Definition:"A cell of hematopoietic origin, typically resident in particular tissues, specialized in the uptake, processing, and transport of antigens to lymph nodes for the purpose of stimulating an immune response via T cell activation. These cells are lineage negative (CD3-negative, CD19-negative, CD34-negative, and CD56-negative)." [GOC:add, ISBN:0781735149]
Xrefs:
links:

BTO:0002042

FMA:83036
Synonyms: "interdigitating cell" RELATED []
"veiled cell" RELATED []


Ontology association <br>Each term has an is_a parent in the Cell ontology, which has a linkage to an another entity and FANTOM5 samples.Libraries were grouped into mutually exclusive facets according to the FANTOM5 sample ontology mapping to Cell ontologies.<br><br>link to ontology dataset<br>data


Parents

is_a:CL:0000738(leukocyte)
disjoint_from:CL:0000542(lymphocyte)



Children


is a:CL:0000784 (plasmacytoid dendritic cell),CL:0000990 (conventional dendritic cell)

Ontology Tree: Loaded from BioPortal

Ontorolgy tree(Small window open)


FF samples<br>It includes FANTOM5 samples that overlay the Cell ontology.


Human (Homo sapiens)

  • 10457-106G7 (squamous cell lung carcinoma cell line:LC-1F)
  • 10501-107C6 (squamous cell lung carcinoma cell line:RERF-LC-AI)
  • 11227-116C3 (Dendritic Cells - monocyte immature derived, donor1)
  • 11228-116C4 (Dendritic Cells - plasmacytoid, donor1)
  • 11308-117C3 (Dendritic Cells - monocyte immature derived, donor2)
  • 11309-117C4 (Dendritic Cells - plasmacytoid, donor2)
  • 11384-118B7 (Dendritic Cells - monocyte immature derived, donor3)
  • 11385-118B8 (Dendritic Cells - plasmacytoid, donor3)
  • 11901-125F2 (migratory langerhans cells, donor1)
  • 11902-125F3 (migratory langerhans cells, donor2)

... further results Mouse (Mus musculus)

  • 10457-106G7 (squamous cell lung carcinoma cell line:LC-1F)
  • 10501-107C6 (squamous cell lung carcinoma cell line:RERF-LC-AI)
  • 11227-116C3 (Dendritic Cells - monocyte immature derived, donor1)
  • 11228-116C4 (Dendritic Cells - plasmacytoid, donor1)
  • 11308-117C3 (Dendritic Cells - monocyte immature derived, donor2)
  • 11309-117C4 (Dendritic Cells - plasmacytoid, donor2)
  • 11384-118B7 (Dendritic Cells - monocyte immature derived, donor3)
  • 11385-118B8 (Dendritic Cells - plasmacytoid, donor3)
  • 11901-125F2 (migratory langerhans cells, donor1)
  • 11902-125F3 (migratory langerhans cells, donor2)

... further results


Enrichment analysis: top 100 FFCP enriched with this ontology termTOP 100 FANTOM5 Cage Peaks enriched with CL:0000451 (dendritic cell), sorted by p-values <br>Analyst: Hideya Kawaji<br><br>link to source dataset <br>human : data <br>mouse : data