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Revision as of 17:42, 15 June 2012

Name:naive regulatory T cell
Namespace:cell
Definition:"A regulatory T cell that has not encountered antigen." [GOC:tfm]
Comments:This cell type has been described as CD45RA-negative, but this doesn't fit with our current definition of naive T cell.
Created by:tmeehan
Creation date:2011-08-25T03:17:21Z


Ontology association <br>Each term has an is_a parent in the Cell ontology, which has a linkage to an another entity and FANTOM5 samples.Libraries were grouped into mutually exclusive facets according to the FANTOM5 sample ontology mapping to Cell ontologies.<br><br>link to ontology dataset<br>data


Parents

is_a:CL:0000792(CD4-positive, CD25-positive, alpha-beta regulatory T cell),CL:0000898(naive T cell)



Children


is a:FF:0011127 (CD4-positiveCD25-positiveCD45RA- naive regulatory T cells expanded),FF:11780-124A7 (CD4+CD25+CD45RA+ naive regulatory T cells, donor1),FF:11782-124A9 (CD4+CD25+CD45RA- memory regulatory T cells, donor1)
derives from:FF:0011128 (human CD4-positiveCD25-positiveCD45RA- naive regulatory T cells sample)

Ontology Tree: Loaded from BioPortal

Ontorolgy tree(Small window open)


FF samples<br>It includes FANTOM5 samples that overlay the Cell ontology.


Human (Homo sapiens)

  • 11780-124A7 (CD4+CD25+CD45RA+ naive regulatory T cells, donor1)
  • 11782-124A9 (CD4+CD25+CD45RA- memory regulatory T cells, donor1)

Mouse (Mus musculus)

  • 11780-124A7 (CD4+CD25+CD45RA+ naive regulatory T cells, donor1)
  • 11782-124A9 (CD4+CD25+CD45RA- memory regulatory T cells, donor1)


Enrichment analysis: top 100 FFCP enriched with this ontology termTOP 100 FANTOM5 Cage Peaks enriched with CL:0002677 (naive regulatory T cell), sorted by p-values <br>Analyst: Hideya Kawaji<br><br>link to source dataset <br>human : data <br>mouse : data