Coexpression cluster:C61

Full id: C61_migratory_Dendritic_immature_Macrophage_xeroderma_cord_b

Phase1 CAGE Peaks

Hg19::chr10:103774322..103774339,-	p@chr10:103774322..103774339 -
Hg19::chr10:112109413..112109419,-	p@chr10:112109413..112109419 -
Hg19::chr10:22556107..22556110,+	p1@ENST00000419532
Hg19::chr10:29822094..29822110,-	p@chr10:29822094..29822110 -
Hg19::chr10:29822118..29822130,-	p@chr10:29822118..29822130 -
Hg19::chr10:61810292..61810302,+	p@chr10:61810292..61810302 +
Hg19::chr10:61810305..61810318,+	p@chr10:61810305..61810318 +
Hg19::chr10:61810336..61810349,+	p@chr10:61810336..61810349 +
Hg19::chr10:76194470..76194496,+	p@chr10:76194470..76194496 +
Hg19::chr11:102188272..102188281,+	p4@BIRC3
Hg19::chr11:107498447..107498449,+	p@chr11:107498447..107498449 +
Hg19::chr11:60712008..60712039,-	p@chr11:60712008..60712039 -
Hg19::chr11:60859819..60859836,-	p@chr11:60859819..60859836 -
Hg19::chr11:60859886..60859898,-	p@chr11:60859886..60859898 -
Hg19::chr11:64365227..64365232,+	p@chr11:64365227..64365232 +
Hg19::chr11:64497276..64497282,-	p@chr11:64497276..64497282 -
Hg19::chr11:64784128..64784143,+	p@chr11:64784128..64784143 +
Hg19::chr11:915207..915220,-	p5@CHID1
Hg19::chr11:915274..915282,-	p12@CHID1
Hg19::chr11:9225193..9225210,-	p@chr11:9225193..9225210 -
Hg19::chr11:9225216..9225230,-	p@chr11:9225216..9225230 -
Hg19::chr12:108599751..108599756,+	p@chr12:108599751..108599756 +
Hg19::chr12:112513512..112513567,-	p@chr12:112513512..112513567 -
Hg19::chr12:112513578..112513587,-	p@chr12:112513578..112513587 -
Hg19::chr12:112563335..112563371,+	p1@TRAFD1
Hg19::chr12:121951651..121951663,-	p@chr12:121951651..121951663 -
Hg19::chr12:121972489..121972509,-	p14@KDM2B
Hg19::chr12:121972519..121972545,-	p10@KDM2B
Hg19::chr12:121972556..121972571,-	p3@KDM2B
Hg19::chr12:131438753..131438771,+	p4@GPR133
Hg19::chr12:131543197..131543202,+	p@chr12:131543197..131543202 +
Hg19::chr12:56552452..56552476,+	p3@MYL6
Hg19::chr12:95211893..95211903,-	p@chr12:95211893..95211903 -
Hg19::chr12:95211919..95211930,-	p@chr12:95211919..95211930 -
Hg19::chr12:95211935..95211951,-	p@chr12:95211935..95211951 -
Hg19::chr12:95258087..95258088,-	p@chr12:95258087..95258088 -
Hg19::chr12:95267426..95267478,-	p@chr12:95267426..95267478 -
Hg19::chr12:95267640..95267650,-	p@chr12:95267640..95267650 -
Hg19::chr13:32672504..32672512,-	p@chr13:32672504..32672512 -
Hg19::chr13:46742630..46742701,-	p3@LCP1
Hg19::chr13:51381967..51381988,+	p3@uc001vey.2
Hg19::chr13:51381989..51382005,+	p1@DLEU7-AS1
Hg19::chr13:51382017..51382022,+	p3@DLEU7-AS1
Hg19::chr13:51382041..51382048,+	p2@DLEU7-AS1
Hg19::chr13:75884283..75884317,-	p@chr13:75884283..75884317 -
Hg19::chr13:75884320..75884362,-	p@chr13:75884320..75884362 -
Hg19::chr14:23707139..23707159,+	p@chr14:23707139..23707159 +
Hg19::chr14:50459798..50459819,-	p1@C14orf182
Hg19::chr14:65641128..65641129,-	p@chr14:65641128..65641129 -
Hg19::chr14:69199933..69199953,-	p@chr14:69199933..69199953 -
Hg19::chr14:69199959..69199970,-	p@chr14:69199959..69199970 -
Hg19::chr15:101534994..101535003,+	p@chr15:101534994..101535003 +
Hg19::chr15:101535004..101535045,+	p@chr15:101535004..101535045 +
Hg19::chr15:44954800..44954825,-	p@chr15:44954800..44954825 -
Hg19::chr16:10850527..10850548,+	p@chr16:10850527..10850548 +
Hg19::chr16:10868999..10869019,-	p5@FAM18A
Hg19::chr16:10869031..10869038,-	p12@FAM18A
Hg19::chr16:10870586..10870591,-	p@chr16:10870586..10870591 -
Hg19::chr16:10885979..10885991,+	p@chr16:10885979..10885991 +
Hg19::chr16:10959804..10959811,+	p5@AB463580
Hg19::chr16:10959868..10959879,+	p2@AB463580
Hg19::chr16:10959880..10959887,+	p6@AB463580
Hg19::chr16:10960091..10960099,+	p3@AB463580
Hg19::chr16:10960104..10960115,+	p4@AB463580
Hg19::chr16:10989793..10989814,+	p@chr16:10989793..10989814 +
Hg19::chr16:14511039..14511043,+	p@chr16:14511039..14511043 +
Hg19::chr16:57392687..57392702,+	p1@CCL22
Hg19::chr16:57394343..57394366,+	p@chr16:57394343..57394366 +
Hg19::chr16:57394384..57394402,+	p@chr16:57394384..57394402 +
Hg19::chr16:57394413..57394431,+	p@chr16:57394413..57394431 +
Hg19::chr16:57394436..57394449,+	p@chr16:57394436..57394449 +
Hg19::chr16:57397411..57397421,+	p@chr16:57397411..57397421 +
Hg19::chr16:57397427..57397438,+	p@chr16:57397427..57397438 +
Hg19::chr16:57397464..57397474,+	p@chr16:57397464..57397474 +
Hg19::chr16:57397519..57397530,+	p@chr16:57397519..57397530 +
Hg19::chr16:57397539..57397560,+	p@chr16:57397539..57397560 +
Hg19::chr16:57397561..57397572,+	p@chr16:57397561..57397572 +
Hg19::chr16:57397581..57397590,+	p@chr16:57397581..57397590 +
Hg19::chr16:57397593..57397602,+	p@chr16:57397593..57397602 +
Hg19::chr16:57397629..57397640,+	p@chr16:57397629..57397640 +
Hg19::chr16:57397653..57397690,+	p@chr16:57397653..57397690 +
Hg19::chr16:57397875..57397886,+	p@chr16:57397875..57397886 +
Hg19::chr16:57397882..57397931,-	p1@CU693343
Hg19::chr16:57397927..57397934,+	p@chr16:57397927..57397934 +
Hg19::chr16:57398105..57398126,+	p@chr16:57398105..57398126 +
Hg19::chr16:57398263..57398266,+	p@chr16:57398263..57398266 +
Hg19::chr16:57398271..57398274,+	p@chr16:57398271..57398274 +
Hg19::chr16:57398283..57398306,+	p@chr16:57398283..57398306 +
Hg19::chr16:57398441..57398460,+	p@chr16:57398441..57398460 +
Hg19::chr16:57399642..57399651,+	p@chr16:57399642..57399651 +
Hg19::chr17:1675324..1675347,+	p@chr17:1675324..1675347 +
Hg19::chr17:19976626..19976659,+	p14@SPECC1
Hg19::chr17:42422929..42422956,+	p@chr17:42422929..42422956 +
Hg19::chr17:42422973..42422983,+	p@chr17:42422973..42422983 +
Hg19::chr17:42423007..42423019,+	p@chr17:42423007..42423019 +
Hg19::chr17:43096311..43096313,+	p@chr17:43096311..43096313 +
Hg19::chr17:43299013..43299038,-	p3@ENST00000498986 p3@uc002iil.3
Hg19::chr17:43394372..43394435,-	p1@MAP3K14
Hg19::chr17:43442243..43442253,-	p@chr17:43442243..43442253 -
Hg19::chr17:4643317..4643359,-	p15@CXCL16
Hg19::chr17:4689649..4689671,-	p1@VMO1
Hg19::chr17:4689735..4689745,-	p2@VMO1
Hg19::chr17:4736789..4736810,+	p2@MINK1
Hg19::chr17:4736812..4736826,+	p4@MINK1
Hg19::chr17:58165660..58165685,-	p1@uc002iyl.2
Hg19::chr17:58165691..58165709,-	p4@uc002iyl.2
Hg19::chr17:58165717..58165743,-	p2@uc002iyl.2
Hg19::chr17:58165788..58165794,-	p1@LOC645638
Hg19::chr17:66218994..66219005,+	p@chr17:66218994..66219005 +
Hg19::chr17:76133866..76133872,+	p23@TMC8
Hg19::chr17:76167616..76167647,+	p@chr17:76167616..76167647 +
Hg19::chr17:7791111..7791123,+	p@chr17:7791111..7791123 +
Hg19::chr17:7792791..7792802,+	p@chr17:7792791..7792802 +
Hg19::chr17:7792820..7792832,+	p@chr17:7792820..7792832 +
Hg19::chr18:56247066..56247080,-	p23@ALPK2
Hg19::chr18:56247086..56247111,-	p24@ALPK2
Hg19::chr18:56320715..56320732,+	p@chr18:56320715..56320732 +
Hg19::chr18:56338677..56338687,+	p5@MALT1
Hg19::chr19:39687556..39687587,+	p2@NCCRP1
Hg19::chr19:39687596..39687612,+	p1@NCCRP1
Hg19::chr19:39687865..39687877,+	p3@NCCRP1
Hg19::chr19:39691473..39691483,+	p@chr19:39691473..39691483 +
Hg19::chr19:39691967..39691971,+	p@chr19:39691967..39691971 +
Hg19::chr19:45231520..45231530,-	p@chr19:45231520..45231530 -
Hg19::chr19:45231533..45231550,-	p@chr19:45231533..45231550 -
Hg19::chr19:45487536..45487571,+	p@chr19:45487536..45487571 +
Hg19::chr19:45487573..45487606,+	p@chr19:45487573..45487606 +
Hg19::chr19:45487650..45487661,+	p@chr19:45487650..45487661 +
Hg19::chr19:45494072..45494085,+	p@chr19:45494072..45494085 +
Hg19::chr19:45494089..45494105,+	p@chr19:45494089..45494105 +
Hg19::chr1:101610610..101610659,-	p@chr1:101610610..101610659 -
Hg19::chr1:101701766..101701778,+	p@chr1:101701766..101701778 +
Hg19::chr1:101701781..101701795,+	p@chr1:101701781..101701795 +
Hg19::chr1:101701841..101701882,+	p8@S1PR1
Hg19::chr1:10555561..10555572,+	p@chr1:10555561..10555572 +
Hg19::chr1:10555579..10555591,+	p@chr1:10555579..10555591 +
Hg19::chr1:112905828..112905838,+	p1@ENST00000454560
Hg19::chr1:151318829..151318851,-	p13@RFX5
Hg19::chr1:153650730..153650735,+	p20@NPR1
Hg19::chr1:153650755..153650771,+	p8@NPR1
Hg19::chr1:154926384..154926395,-	p9@PBXIP1
Hg19::chr1:156123108..156123151,+	p18@SEMA4A
Hg19::chr1:157105581..157105601,-	p@chr1:157105581..157105601 -
Hg19::chr1:157108746..157108762,-	p4@ETV3
Hg19::chr1:157108764..157108776,-	p7@ETV3
Hg19::chr1:172750924..172750932,+	p@chr1:172750924..172750932 +
Hg19::chr1:172751007..172751015,+	p@chr1:172751007..172751015 +
Hg19::chr1:172751022..172751037,+	p@chr1:172751022..172751037 +
Hg19::chr1:172751066..172751077,+	p@chr1:172751066..172751077 +
Hg19::chr1:179921630..179921633,+	p@chr1:179921630..179921633 +
Hg19::chr1:201368775..201368784,-	p7@LAD1
Hg19::chr1:201369034..201369048,-	p5@LAD1
Hg19::chr1:229761379..229761405,-	p@chr1:229761379..229761405 -
Hg19::chr1:25194616..25194628,-	p@chr1:25194616..25194628 -
Hg19::chr1:25197198..25197207,+	p@chr1:25197198..25197207 +
Hg19::chr1:40846881..40846909,+	p@chr1:40846881..40846909 +
Hg19::chr1:5433418..5433419,+	p@chr1:5433418..5433419 +
Hg19::chr1:6342341..6342360,-	p@chr1:6342341..6342360 -
Hg19::chr1:66779048..66779059,-	p@chr1:66779048..66779059 -
Hg19::chr1:85462899..85462931,+	p@chr1:85462899..85462931 +
Hg19::chr1:8935456..8935467,-	p27@ENO1
Hg19::chr1:8935472..8935488,-	p20@ENO1
Hg19::chr1:9163159..9163164,-	p@chr1:9163159..9163164 -
Hg19::chr1:9189144..9189195,-	p1@GPR157
Hg19::chr1:9189245..9189259,-	p2@GPR157
Hg19::chr20:20406322..20406332,-	p@chr20:20406322..20406332 -
Hg19::chr20:20406346..20406351,-	p@chr20:20406346..20406351 -
Hg19::chr20:20418113..20418139,-	p@chr20:20418113..20418139 -
Hg19::chr20:22897338..22897344,+	p2@uc002wsp.2
Hg19::chr20:4768596..4768628,-	p@chr20:4768596..4768628 -
Hg19::chr20:4803330..4803352,-	p@chr20:4803330..4803352 -
Hg19::chr21:16090226..16090249,-	p@chr21:16090226..16090249 -
Hg19::chr21:35894884..35894895,+	p@chr21:35894884..35894895 +
Hg19::chr22:25815778..25815803,+	p@chr22:25815778..25815803 +
Hg19::chr22:35807395..35807398,+	p13@MCM5
Hg19::chr22:36616659..36616668,+	p@chr22:36616659..36616668 +
Hg19::chr22:38609538..38609547,+	p8@MAFF
Hg19::chr22:45705979..45705986,+	p9@FAM118A
Hg19::chr22:45705987..45706022,+	p2@FAM118A
Hg19::chr22:50986685..50986727,+	p2@CU679553
Hg19::chr2:101179263..101179284,+	p3@PDCL3
Hg19::chr2:101179291..101179310,+	p5@PDCL3
Hg19::chr2:101179484..101179502,+	p2@PDCL3
Hg19::chr2:102758335..102758346,+	p30@IL1R1
Hg19::chr2:102758378..102758401,+	p31@IL1R1
Hg19::chr2:158336391..158336415,+	p@chr2:158336391..158336415 +
Hg19::chr2:158606314..158606346,-	p@chr2:158606314..158606346 -
Hg19::chr2:160761179..160761275,-	p1@LY75-CD302 p1@LY75
Hg19::chr2:206587174..206587196,+	p17@NRP2
Hg19::chr2:208018487..208018495,-	p@chr2:208018487..208018495 -
Hg19::chr2:216986721..216986726,+	p29@XRCC5
Hg19::chr2:231790767..231790779,-	p@chr2:231790767..231790779 -
Hg19::chr2:231808578..231808581,+	p@chr2:231808578..231808581 +
Hg19::chr2:238767219..238767230,+	p7@RAMP1
Hg19::chr2:238767237..238767248,+	p5@RAMP1
Hg19::chr2:238767346..238767363,+	p2@RAMP1
Hg19::chr2:238767388..238767402,+	p4@RAMP1
Hg19::chr2:238767517..238767539,+	p3@RAMP1
Hg19::chr2:238810193..238810202,+	p@chr2:238810193..238810202 +
Hg19::chr2:27434497..27434509,-	p19@SLC5A6
Hg19::chr2:45640405..45640412,-	p@chr2:45640405..45640412 -
Hg19::chr2:50936065..50936067,+	p@chr2:50936065..50936067 +
Hg19::chr2:61081057..61081064,+	p@chr2:61081057..61081064 +
Hg19::chr2:65593906..65593917,-	p11@SPRED2
Hg19::chr2:71056842..71056868,+	p@chr2:71056842..71056868 +
Hg19::chr3:119188696..119188702,+	p@chr3:119188696..119188702 +
Hg19::chr3:119188705..119188718,+	p@chr3:119188705..119188718 +
Hg19::chr3:119198717..119198735,+	p@chr3:119198717..119198735 +
Hg19::chr3:119278515..119278527,-	p5@CD80
Hg19::chr3:182871832..182871843,-	p@chr3:182871832..182871843 -
Hg19::chr3:182871844..182871855,-	p@chr3:182871844..182871855 -
Hg19::chr3:182871897..182871916,-	p@chr3:182871897..182871916 -
Hg19::chr3:182871928..182871939,-	p@chr3:182871928..182871939 -
Hg19::chr3:182872005..182872022,-	p@chr3:182872005..182872022 -
Hg19::chr3:182872047..182872055,-	p@chr3:182872047..182872055 -
Hg19::chr3:182872057..182872068,-	p@chr3:182872057..182872068 -
Hg19::chr3:182872082..182872093,-	p@chr3:182872082..182872093 -
Hg19::chr3:182872116..182872132,-	p@chr3:182872116..182872132 -
Hg19::chr3:182872144..182872153,-	p@chr3:182872144..182872153 -
Hg19::chr3:182872174..182872187,-	p@chr3:182872174..182872187 -
Hg19::chr3:182880514..182880528,-	p1@LAMP3
Hg19::chr3:182880541..182880578,-	p2@LAMP3
Hg19::chr3:197585687..197585697,+	p3@LRCH3
Hg19::chr3:52813932..52813943,+	p11@ITIH1
Hg19::chr3:52813951..52813958,+	p13@ITIH1
Hg19::chr3:52813997..52814015,+	p9@ITIH1
Hg19::chr3:98989626..98989627,+	p@chr3:98989626..98989627 +
Hg19::chr4:103478257..103478273,+	p28@NFKB1
Hg19::chr4:119947900..119947917,+	p9@SYNPO2
Hg19::chr4:119947953..119947968,+	p20@SYNPO2
Hg19::chr4:14845952..14845956,-	p@chr4:14845952..14845956 -
Hg19::chr4:160141656..160141659,+	p@chr4:160141656..160141659 +
Hg19::chr4:78079509..78079563,+	p3@CCNG2
Hg19::chr4:78079570..78079586,+	p7@CCNG2
Hg19::chr4:78079649..78079662,+	p19@CCNG2
Hg19::chr4:83563607..83563621,-	p@chr4:83563607..83563621 -
Hg19::chr4:83602084..83602095,-	p23@SCD5
Hg19::chr5:75858160..75858165,+	p@chr5:75858160..75858165 +
Hg19::chr6:106340773..106340776,-	p@chr6:106340773..106340776 -
Hg19::chr6:106340792..106340805,-	p@chr6:106340792..106340805 -
Hg19::chr6:106340812..106340852,-	p@chr6:106340812..106340852 -
Hg19::chr6:106340857..106340862,-	p@chr6:106340857..106340862 -
Hg19::chr6:20723063..20723072,+	p@chr6:20723063..20723072 +
Hg19::chr6:26383377..26383395,+	p3@BTN2A2
Hg19::chr6:32605173..32605190,+	p1@HLA-DQA1
Hg19::chr6:32609190..32609204,+	p18@HLA-DQA1
Hg19::chr6:32610515..32610535,+	p16@HLA-DQA1
Hg19::chr6:32610814..32610817,+	p28@HLA-DQA1
Hg19::chr6:32610846..32610863,+	p5@HLA-DQA1
Hg19::chr6:33055198..33055203,+	p@chr6:33055198..33055203 +
Hg19::chr6:33107633..33107670,-	p@chr6:33107633..33107670 -
Hg19::chr6:41123284..41123294,-	p@chr6:41123284..41123294 -
Hg19::chr6:6862008..6862024,-	p@chr6:6862008..6862024 -
Hg19::chr7:106505959..106505980,+	p4@PIK3CG
Hg19::chr7:106505988..106506018,+	p6@PIK3CG
Hg19::chr7:106888874..106888913,-	p@chr7:106888874..106888913 -
Hg19::chr7:106889102..106889113,-	p@chr7:106889102..106889113 -
Hg19::chr7:111700086..111700089,-	p@chr7:111700086..111700089 -
Hg19::chr7:150066722..150066738,+	p10@REPIN1
Hg19::chr7:150070749..150070799,+	p@chr7:150070749..150070799 +
Hg19::chr7:150102756..150102772,+	p5@ZNF775
Hg19::chr7:150479143..150479154,-	p@chr7:150479143..150479154 -
Hg19::chr7:150497625..150497646,-	p10@TMEM176B
Hg19::chr7:150498814..150498826,-	p8@TMEM176B
Hg19::chr7:150498868..150498890,+	p11@TMEM176A
Hg19::chr7:150520561..150520563,+	p@chr7:150520561..150520563 +
Hg19::chr7:151038850..151038915,+	p1@NUB1
Hg19::chr7:22761970..22762002,-	p@chr7:22761970..22762002 -
Hg19::chr7:22762017..22762024,-	p@chr7:22762017..22762024 -
Hg19::chr7:30619042..30619046,-	p@chr7:30619042..30619046 -
Hg19::chr7:6427818..6427822,+	p@chr7:6427818..6427822 +
Hg19::chr7:6431430..6431437,+	p@chr7:6431430..6431437 +
Hg19::chr8:39771370..39771382,+	p2@IDO1
Hg19::chr8:39771400..39771420,+	p1@IDO1
Hg19::chr8:39818857..39818873,+	p@chr8:39818857..39818873 +
Hg19::chr9:102587069..102587091,+	p@chr9:102587069..102587091 +
Hg19::chr9:113018779..113018796,-	p1@TXN
Hg19::chr9:135665233..135665245,-	p@chr9:135665233..135665245 -
Hg19::chr9:140056300..140056307,+	p@chr9:140056300..140056307 +
Hg19::chr9:35227706..35227717,+	p5@UNC13B
Hg19::chr9:35227753..35227762,+	p6@UNC13B
Hg19::chrX:108780205..108780217,+	p6@NXT2
Hg19::chrX:13707235..13707286,+	p1@RAB9A
Hg19::chrX:13707290..13707304,+	p2@RAB9A
Hg19::chrX:66877253..66877260,-	p@chrX:66877253..66877260 -
Hg19::chrX:78200913..78200947,+	p2@P2RY10

Enriched pathways on this co-expression cluster<b>Summary:</b><br>Canonical pathway gene sets were compiled from Reactome, Wikipathways and KEGG. For the major signaling pathways, the transcriptionally-regulated genes (downstream targets) were obtained from Netpath. Combined, the canonical pathways and downstream targets totaled 489 human gene sets. The corresponding M. musculus gene sets were inferred by homology using the HomoloGene database. Enrichment for each of the canonical 489 pathways and gene sets included in the co-expression cluster was assessed by the hypergeometric probability. The resulting P values were also then adjusted by the Benjamini-Hochberg method for multiple comparisons.<br><b>Analyst: </b>Emmanuel Dimont<br><br>link to source dataset<br>data

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p.value	FDR	nGenes	nPathway	Name
0.000723495633320979	0.02693957269954	4	189	Chemokine signaling pathway (KEGG):04062
1.14932691900024e-06	0.000363761969863575	5	86	Apoptosis (KEGG):04210
0.00198207686361645	0.0482559482565083	3	116	Vascular smooth muscle contraction (KEGG):04270
0.000165140566465295	0.0171610173803105	4	128	Osteoclast differentiation (KEGG):04380
0.00137145006955941	0.0377446910448308	3	102	Toll-like receptor signaling pathway (KEGG):04620
8.56423035042436e-05	0.0135528945295466	4	108	T cell receptor signaling pathway (KEGG):04660
0.000561879558600461	0.025404982899578	3	75	B cell receptor signaling pathway (KEGG):04662
0.000159480877596477	0.0171610173803105	3	49	Intestinal immune network for IgA production (KEGG):04672
0.000191313229292521	0.0171610173803105	4	133	Toxoplasmosis (KEGG):05145
0.00153164363893432	0.0403971009768928	3	106	Amoebiasis (KEGG):05146
0.000628293405730547	0.0265139817218291	4	182	Tuberculosis (KEGG):05152
0.000554077106577416	0.025404982899578	4	176	Influenza A (KEGG):05164
0.000809502563905301	0.0269692169974766	3	85	Small cell lung cancer (KEGG):05222
0.000243995507776927	0.0171610173803105	2	11	Osteopontin Signaling (Wikipathways):WP1434
0.000232815478918128	0.0171610173803105	4	140	Regulation of toll-like receptor signaling pathway (Wikipathways):WP1449
0.000866088111557347	0.02741168873079	3	87	MicroRNAs in cardiomyocyte hypertrophy (Wikipathways):WP1544
2.77565538333288e-05	0.00585663285883237	4	81	Apoptosis Modulation and Signaling (Wikipathways):WP1772
0.000709308355343682	0.02693957269954	4	188	TNF-alpha/NF-kB Signaling Pathway (Wikipathways):WP231
0.00100938566684373	0.0304257679577181	2	22	EBV LMP1 signaling (Wikipathways):WP262
0.000405452167106626	0.0213876018148745	4	162	MAPK signaling pathway (Wikipathways):WP382
0.00137145006955941	0.0377446910448308	3	102	Toll-like receptor signaling pathway (Wikipathways):WP75
0.000771236240077837	0.0269692169974766	6	511	Signaling in Immune system (Reactome):REACT_6900
0.000405452167106626	0.0213876018148745	4	162	TNF alpha/NF-kB down reg. targets (Netpath):NetPath_9
0.00191127452866547	0.0482559482565083	4	246	B Cell Receptor up reg. targets (Netpath):NetPath_12
0.000343004633768695	0.0213876018148745	4	155	IL-1 up reg. targets (Netpath):NetPath_13
2.04164496673815e-08	1.29236126394525e-05	8	217	IL-4 up reg. targets (Netpath):NetPath_16

Enriched Gene Ontology terms on this co-expression cluster<b>Summary:</b> Results for GOStat analysis on co-expressed clusters. Each cluster with promoters mapping to at least two different genes was analysed with GOStat (PMID: 14962934) with default parameter. <br><b>Analyst:</b> Erik Arner<br><br>link to source dataset<br>data

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GO ID	GO name	FDR corrected p-value
GO:0032502	developmental process	0.000377841516044536
GO:0048869	cellular developmental process	0.00628566792223742
GO:0030154	cell differentiation	0.00628566792223742
GO:0005886	plasma membrane	0.0494507038038988
GO:0043066	negative regulation of apoptosis	0.0494507038038988
GO:0032623	interleukin-2 production	0.0494507038038988
GO:0043069	negative regulation of programmed cell death	0.0494507038038988
GO:0044464	cell part	0.0494507038038988

Enriched sample ontology terms on this co-expression cluster<b>Summary:</b>To summarize promoter activities (expression profile of a TSS region) across ~1000 samples, we performed enrichment analysis based on FANTOM5 Sample Ontology (FF ontology). The question here is “in which type of samples the promoter is more active”. To answer this question, we compared expressions (TPMs) in the samples associated with a sample ontology term and the rest of the samples by using the Mann-Whitney rank sum test. To summarize ontologies enriched in this co-expression cluster, we ran the same analysis on an averaged expression profile of all promoters that make up. <b>Analyst:</b> Hideya Kawaji <br><br>links to source dataset<br><br>cell_data<br>uberon_data<br><br>

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Cell Type

Ontology term	p-value	n
leukocyte	5.89e-46	140
nongranular leukocyte	2.48e-36	119
hematopoietic lineage restricted progenitor cell	1.09e-35	124
myeloid leukocyte	4.12e-27	76
hematopoietic stem cell	1.17e-24	172
angioblastic mesenchymal cell	1.17e-24	172
granulocyte monocyte progenitor cell	9.60e-24	71
hematopoietic cell	3.26e-23	182
hematopoietic oligopotent progenitor cell	3.90e-23	165
hematopoietic multipotent progenitor cell	3.90e-23	165
macrophage dendritic cell progenitor	3.99e-23	65
monopoietic cell	7.76e-22	63
monocyte	7.76e-22	63
monoblast	7.76e-22	63
promonocyte	7.76e-22	63
myeloid lineage restricted progenitor cell	1.87e-21	70
CD14-positive, CD16-negative classical monocyte	5.56e-21	42
classical monocyte	2.19e-19	45
lymphocyte	4.55e-13	53
common lymphoid progenitor	4.55e-13	53
lymphoid lineage restricted progenitor cell	1.31e-12	52
myeloid cell	6.37e-11	112
common myeloid progenitor	6.37e-11	112
lymphocyte of B lineage	2.19e-09	24
pro-B cell	2.19e-09	24
dendritic cell	2.30e-08	10
conventional dendritic cell	2.03e-07	8

Uber Anatomy

Ontology term	p-value	n
hematopoietic system	9.54e-28	102
blood island	9.54e-28	102
hemolymphoid system	1.27e-26	112
bone marrow	2.65e-19	80
bone element	9.48e-17	86
immune system	2.21e-15	115
skeletal element	2.67e-12	101
skeletal system	2.67e-12	101
adult organism	1.06e-10	115
blood	9.54e-07	15
haemolymphatic fluid	9.54e-07	15
organism substance	9.54e-07	15

Overrepresented TFBS (DNA) motifs on this co-expression cluster<b>Summary:</b>The values shown are the p-values for overrepresentation of the motif in this coexpression cluster. So a small p-value means a strong overrepresentation. <b>Analyst:</b> Michiel de Hoon <br><br>link to source data <br> Novel motifs <br>data <br><br> Jaspar motifs <br>data

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Novel motifs

JASPAR motifs

Motifs	-log10(p-value)
{{{tfbs_overrepresentation_jaspar}}}

ENCODE TF ChIP-seq peak enrichment analysis<b>Summary:</b> For each TF and each co-expression cluster, the number of promoters with ENCODE TF ChIP signal was compared with the rest of promoters from the robust set using Fisher's exact test. Clusters with significant ChIP enrichment (q <= 0.05) after Benjamini-Hochberg correction were retained. <br><b>Analyst:</b> Erik Arner<br><br>link to source dataset<br><br>data

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(#promoters = Number of promoters in this coexpression cluster that have ChIP signal of the TF)

TF	#promoters	Enrichment	p-value	q-value
BATF#10538	22	1.87367706094643	0.00391317268546165	0.0190690482501367
EBF1#1879	46	1.43250865364397	0.00814370014143584	0.0321594093496963
MAFK#7975	21	1.98991397165884	0.00240863050879276	0.0135799482675344
MEF2A#4205	25	1.63839431028357	0.0112307606300385	0.0412335445911759
NFKB1#4790	70	1.34323230662087	0.00493225098634385	0.0230488773888212
RXRA#6256	26	1.82496519446666	0.0025098476887578	0.0140769014964919
SPI1#6688	56	1.60644096670375	0.000232848988002803	0.00255822800947031

Relative expression of the co-expression cluster<b>Summary:</b>Co-expression clusters are compared against FANTOM5 samples to obtain relative expression. <br><b>Analyst:</b>NA<br><br>link to data source<br> data

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