MCL coexpression mm9:1078

Phase1 CAGE Peaks

	Short description
Mm9::chr11:55220048..55220060,+	p@chr11:55220048..55220060 +
Mm9::chr7:106495646..106495676,-	p@chr7:106495646..106495676 -
Mm9::chr7:106497424..106497441,+	p@chr7:106497424..106497441 +
Mm9::chr7:106497508..106497559,-	p@chr7:106497508..106497559 -
Mm9::chr7:106497588..106497613,-	p@chr7:106497588..106497613 -
Mm9::chr7:106497675..106497687,-	p@chr7:106497675..106497687 -
Mm9::chr7:86293928..86293948,-	p2@Mfge8

Enriched pathways on this co-expression cluster<b>Summary:</b><br>Canonical pathway gene sets were compiled from Reactome, Wikipathways and KEGG. For the major signaling pathways, the transcriptionally-regulated genes (downstream targets) were obtained from Netpath. Combined, the canonical pathways and downstream targets totaled 489 human gene sets. The corresponding M. musculus gene sets were inferred by homology using the HomoloGene database. Enrichment for each of the canonical 489 pathways and gene sets included in the co-expression cluster was assessed by the hypergeometric probability. The resulting P values were also then adjusted by the Benjamini-Hochberg method for multiple comparisons.<br><b>Analyst: </b>Emmanuel Dimont<br><br>link to source dataset<br>data

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GO ID	GO name	FDR corrected p-value
GO:0008429	phosphatidylethanolamine binding	0.0111756326709401
GO:0001786	phosphatidylserine binding	0.0111756326709401
GO:0006910	phagocytosis, recognition	0.0198607156030382
GO:0006911	phagocytosis, engulfment	0.0198607156030382
GO:0050766	positive regulation of phagocytosis	0.0198607156030382
GO:0050764	regulation of phagocytosis	0.0198607156030382
GO:0045807	positive regulation of endocytosis	0.0204779951512838
GO:0005178	integrin binding	0.0204779951512838
GO:0009408	response to heat	0.0206689683680001
GO:0051050	positive regulation of transport	0.0206689683680001
GO:0030100	regulation of endocytosis	0.0206689683680001
GO:0006909	phagocytosis	0.0206689683680001
GO:0007338	single fertilization	0.0206689683680001
GO:0008037	cell recognition	0.0206689683680001
GO:0009266	response to temperature stimulus	0.0206689683680001
GO:0009566	fertilization	0.0206689683680001
GO:0032403	protein complex binding	0.0206689683680001
GO:0019897	extrinsic to plasma membrane	0.0206689683680001
GO:0051082	unfolded protein binding	0.0227091238159021
GO:0019898	extrinsic to membrane	0.025657479305141
GO:0051049	regulation of transport	0.0297355554952831
GO:0004867	serine-type endopeptidase inhibitor activity	0.034112378156982
GO:0005615	extracellular space	0.0344229673627489
GO:0044421	extracellular region part	0.0370600414302398
GO:0009897	external side of plasma membrane	0.0401296360079547
GO:0004866	endopeptidase inhibitor activity	0.0401296360079547
GO:0030414	protease inhibitor activity	0.0401296360079547
GO:0010324	membrane invagination	0.0415337643679454
GO:0006897	endocytosis	0.0415337643679454
GO:0009628	response to abiotic stimulus	0.0415337643679454
GO:0009986	cell surface	0.0442405047433432
GO:0005543	phospholipid binding	0.0448897475434736
GO:0022414	reproductive process	0.0448897475434736
GO:0004857	enzyme inhibitor activity	0.0448897475434736
GO:0016044	membrane organization and biogenesis	0.0492860006314063

Relative expression of the co-expression cluster over median <br>Analyst:

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Enriched sample ontology terms on this co-expression cluster<b>Summary:</b>To summarize promoter activities (expression profile of a TSS region) across ~1000 samples, we performed enrichment analysis based on FANTOM5 Sample Ontology (FF ontology). The question here is “in which type of samples the promoter is more active”. To answer this question, we compared expressions (TPMs) in the samples associated with a sample ontology term and the rest of the samples by using the Mann-Whitney rank sum test. To summarize ontologies enriched in this co-expression cluster, we ran the same analysis on an averaged expression profile of all promoters that make up. <b>Analyst:</b> Hideya Kawaji <br><br>links to source dataset<br><br>cell_data<br>uberon_data<br>disease_data<br>

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Cell Type

Ontology term	p-value	n

Uber Anatomy

Ontology term	p-value	n

Disease

Ontology term	p-value	n

TFBS overrepresentation<b>Summary:</b>The values shown are the p-values for overrepresentation of the motif in this coexpression cluster. So a small p-value means a strong overrepresentation. <b>Analyst:</b> Michiel de Hoon <br><br>link to source data <br> Novel motifs <br>data <br><br> Jaspar motifs <br>data

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Novel motifs

JASPAR motifs

Motifs	-log10(p-value)
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