MCL coexpression mm9:561

Phase1 CAGE Peaks

	Short description
Mm9::chr11:51420342..51420359,-	p1@Hnrnpab
Mm9::chr11:96650463..96650520,+	p2@Cbx1
Mm9::chr11:96650527..96650538,+	p3@Cbx1
Mm9::chr18:56867379..56867594,+	p1@Lmnb1
Mm9::chr18:56867595..56867642,+	p2@Lmnb1
Mm9::chr2:29922008..29922050,+	p1@Set
Mm9::chr2:29922058..29922087,+	p4@Set
Mm9::chr2:4802802..4802818,+	p2@Sephs1
Mm9::chr3:151873433..151873498,+	p1@Fubp1
Mm9::chr5:100407933..100407985,-	p1@Hnrnpd
Mm9::chr6:18798604..18798693,+	p1@Naa38
Mm9::chr9:110034519..110034606,+	p1@Smarcc1
Mm9::chrX:98624993..98625047,+	p1@Nono

Enriched pathways on this co-expression cluster<b>Summary:</b><br>Canonical pathway gene sets were compiled from Reactome, Wikipathways and KEGG. For the major signaling pathways, the transcriptionally-regulated genes (downstream targets) were obtained from Netpath. Combined, the canonical pathways and downstream targets totaled 489 human gene sets. The corresponding M. musculus gene sets were inferred by homology using the HomoloGene database. Enrichment for each of the canonical 489 pathways and gene sets included in the co-expression cluster was assessed by the hypergeometric probability. The resulting P values were also then adjusted by the Benjamini-Hochberg method for multiple comparisons.<br><b>Analyst: </b>Emmanuel Dimont<br><br>link to source dataset<br>data

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GO ID	GO name	FDR corrected p-value
GO:0006333	chromatin assembly or disassembly	0.00167154048853748
GO:0006259	DNA metabolic process	0.00267532743741777
GO:0006325	establishment and/or maintenance of chromatin architecture	0.00382075892357918
GO:0006323	DNA packaging	0.00382075892357918
GO:0051276	chromosome organization and biogenesis	0.00782676507747672
GO:0005634	nucleus	0.010352760363296
GO:0003682	chromatin binding	0.010352760363296
GO:0043283	biopolymer metabolic process	0.010352760363296
GO:0004756	selenide, water dikinase activity	0.010352760363296
GO:0016781	phosphotransferase activity, paired acceptors	0.010352760363296
GO:0005701	polytene chromosome chromocenter	0.0129388234465679
GO:0005700	polytene chromosome	0.0129388234465679
GO:0005721	centric heterochromatin	0.0137991432826624
GO:0005638	lamin filament	0.0137991432826624
GO:0001940	male pronucleus	0.0137991432826624
GO:0006139	nucleobase, nucleoside, nucleotide and nucleic acid metabolic process	0.0140998553424081
GO:0001939	female pronucleus	0.0152171418786361
GO:0000785	chromatin	0.0155189337054456
GO:0010369	chromocenter	0.0155189337054456
GO:0016514	SWI/SNF complex	0.0155189337054456
GO:0003677	DNA binding	0.0179870528483271
GO:0005652	nuclear lamina	0.0179870528483271
GO:0005637	nuclear inner membrane	0.0179870528483271
GO:0043170	macromolecule metabolic process	0.018211026510159
GO:0044428	nuclear part	0.0242749379943623
GO:0044427	chromosomal part	0.026787604125647
GO:0045120	pronucleus	0.026787604125647
GO:0006996	organelle organization and biogenesis	0.0305470632527692
GO:0044238	primary metabolic process	0.0305470632527692
GO:0044237	cellular metabolic process	0.0305470632527692
GO:0005694	chromosome	0.0305470632527692
GO:0016585	chromatin remodeling complex	0.0305470632527692
GO:0043231	intracellular membrane-bound organelle	0.0305470632527692
GO:0043227	membrane-bound organelle	0.0305470632527692
GO:0005720	nuclear heterochromatin	0.0338990160233967
GO:0003676	nucleic acid binding	0.0420275964709632
GO:0000790	nuclear chromatin	0.0420275964709632
GO:0008430	selenium binding	0.0420275964709632
GO:0000792	heterochromatin	0.0463176859807975
GO:0043232	intracellular non-membrane-bound organelle	0.0463176859807975
GO:0043228	non-membrane-bound organelle	0.0463176859807975
GO:0043229	intracellular organelle	0.0480738099214408
GO:0043226	organelle	0.0480738099214408
GO:0003723	RNA binding	0.0499254134235463

Relative expression of the co-expression cluster over median <br>Analyst:

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Enriched sample ontology terms on this co-expression cluster<b>Summary:</b>To summarize promoter activities (expression profile of a TSS region) across ~1000 samples, we performed enrichment analysis based on FANTOM5 Sample Ontology (FF ontology). The question here is “in which type of samples the promoter is more active”. To answer this question, we compared expressions (TPMs) in the samples associated with a sample ontology term and the rest of the samples by using the Mann-Whitney rank sum test. To summarize ontologies enriched in this co-expression cluster, we ran the same analysis on an averaged expression profile of all promoters that make up. <b>Analyst:</b> Hideya Kawaji <br><br>links to source dataset<br><br><br>uberon_data<br><br>

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Uber Anatomy

Ontology term	p-value	n
anterior region of body	5.61e-08	43

TFBS overrepresentation<b>Summary:</b>The values shown are the p-values for overrepresentation of the motif in this coexpression cluster. So a small p-value means a strong overrepresentation. <b>Analyst:</b> Michiel de Hoon <br><br>link to source data <br> Novel motifs <br>data <br><br> Jaspar motifs <br>data

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Novel motifs

JASPAR motifs

Motifs	-log10(p-value)
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