MCL coexpression mm9:699

Phase1 CAGE Peaks

	Short description
Mm9::chr11:109856955..109856967,-	p5@Abca8b
Mm9::chr14:57239396..57239401,-	p2@ENSMUST00000161382 p2@ENSMUST00000162231
Mm9::chr16:31168077..31168081,-	p@chr16:31168077..31168081 -
Mm9::chr19:39815489..39815518,-	p@chr19:39815489..39815518 -
Mm9::chr19:46743077..46743093,+	p@chr19:46743077..46743093 +
Mm9::chr3:6802683..6802687,-	p@chr3:6802683..6802687 -
Mm9::chr3:82812587..82812624,-	p@chr3:82812587..82812624 -
Mm9::chrX:147028881..147028901,+	p5@Pfkfb1
Mm9::chrX:147028936..147028956,+	p4@Pfkfb1
Mm9::chrX:147028963..147028989,+	p3@Pfkfb1

Enriched pathways on this co-expression cluster<b>Summary:</b><br>Canonical pathway gene sets were compiled from Reactome, Wikipathways and KEGG. For the major signaling pathways, the transcriptionally-regulated genes (downstream targets) were obtained from Netpath. Combined, the canonical pathways and downstream targets totaled 489 human gene sets. The corresponding M. musculus gene sets were inferred by homology using the HomoloGene database. Enrichment for each of the canonical 489 pathways and gene sets included in the co-expression cluster was assessed by the hypergeometric probability. The resulting P values were also then adjusted by the Benjamini-Hochberg method for multiple comparisons.<br><b>Analyst: </b>Emmanuel Dimont<br><br>link to source dataset<br>data

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GO ID	GO name	FDR corrected p-value
GO:0004331	fructose-2,6-bisphosphate 2-phosphatase activity	0.0160212513531023
GO:0003873	6-phosphofructo-2-kinase activity	0.0160212513531023
GO:0006003	fructose 2,6-bisphosphate metabolic process	0.0160212513531023
GO:0006000	fructose metabolic process	0.0160212513531023
GO:0008443	phosphofructokinase activity	0.0192212882000167
GO:0019203	carbohydrate phosphatase activity	0.0192212882000167

Relative expression of the co-expression cluster over median <br>Analyst:

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Enriched sample ontology terms on this co-expression cluster<b>Summary:</b>To summarize promoter activities (expression profile of a TSS region) across ~1000 samples, we performed enrichment analysis based on FANTOM5 Sample Ontology (FF ontology). The question here is “in which type of samples the promoter is more active”. To answer this question, we compared expressions (TPMs) in the samples associated with a sample ontology term and the rest of the samples by using the Mann-Whitney rank sum test. To summarize ontologies enriched in this co-expression cluster, we ran the same analysis on an averaged expression profile of all promoters that make up. <b>Analyst:</b> Hideya Kawaji <br><br>links to source dataset<br><br><br>uberon_data<br><br>

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Uber Anatomy

Ontology term	p-value	n
liver	1.10e-24	22
epithelial sac	1.10e-24	22
digestive gland	1.10e-24	22
epithelium of foregut-midgut junction	1.10e-24	22
anatomical boundary	1.10e-24	22
hepatobiliary system	1.10e-24	22
foregut-midgut junction	1.10e-24	22
hepatic diverticulum	1.10e-24	22
liver primordium	1.10e-24	22
septum transversum	1.10e-24	22
liver bud	1.10e-24	22
digestive tract diverticulum	2.53e-23	23
sac	2.53e-23	23
exocrine gland	6.25e-21	25
exocrine system	6.25e-21	25
trunk mesenchyme	5.79e-13	45
abdomen element	2.48e-11	49
abdominal segment element	2.48e-11	49
abdominal segment of trunk	2.48e-11	49
abdomen	2.48e-11	49
epithelial tube	5.21e-10	47
endocrine gland	5.01e-08	60
mesenchyme	8.65e-08	61
entire embryonic mesenchyme	8.65e-08	61
gland	6.38e-07	65

TFBS overrepresentation<b>Summary:</b>The values shown are the p-values for overrepresentation of the motif in this coexpression cluster. So a small p-value means a strong overrepresentation. <b>Analyst:</b> Michiel de Hoon <br><br>link to source data <br> Novel motifs <br>data <br><br> Jaspar motifs <br>data

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Novel motifs

JASPAR motifs

Motifs	-log10(p-value)
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