MCL coexpression mm9:3157

Phase1 CAGE Peaks

	Short description
Mm9::chr18:66162266..66162291,-	p1@Lman1
Mm9::chr8:42219005..42219017,-	p12@Mtus1
Mm9::chr8:42219051..42219109,-	p2@Mtus1

Enriched pathways on this co-expression cluster<b>Summary:</b><br>Canonical pathway gene sets were compiled from Reactome, Wikipathways and KEGG. For the major signaling pathways, the transcriptionally-regulated genes (downstream targets) were obtained from Netpath. Combined, the canonical pathways and downstream targets totaled 489 human gene sets. The corresponding M. musculus gene sets were inferred by homology using the HomoloGene database. Enrichment for each of the canonical 489 pathways and gene sets included in the co-expression cluster was assessed by the hypergeometric probability. The resulting P values were also then adjusted by the Benjamini-Hochberg method for multiple comparisons.<br><b>Analyst: </b>Emmanuel Dimont<br><br>link to source dataset<br>data

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GO ID	GO name	FDR corrected p-value
GO:0005793	ER-Golgi intermediate compartment	0.0188446682258026
GO:0005794	Golgi apparatus	0.0196283784355713
GO:0006888	ER to Golgi vesicle-mediated transport	0.0251179638509013
GO:0048193	Golgi vesicle transport	0.0447143975768353
GO:0030017	sarcomere	0.0452542954370894
GO:0044449	contractile fiber part	0.0452542954370894
GO:0030016	myofibril	0.0452542954370894
GO:0043292	contractile fiber	0.0452542954370894

Relative expression of the co-expression cluster over median <br>Analyst:

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Enriched sample ontology terms on this co-expression cluster<b>Summary:</b>To summarize promoter activities (expression profile of a TSS region) across ~1000 samples, we performed enrichment analysis based on FANTOM5 Sample Ontology (FF ontology). The question here is “in which type of samples the promoter is more active”. To answer this question, we compared expressions (TPMs) in the samples associated with a sample ontology term and the rest of the samples by using the Mann-Whitney rank sum test. To summarize ontologies enriched in this co-expression cluster, we ran the same analysis on an averaged expression profile of all promoters that make up. <b>Analyst:</b> Hideya Kawaji <br><br>links to source dataset<br><br><br>uberon_data<br><br>

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Uber Anatomy

Ontology term	p-value	n
trunk region element	3.05e-10	79
immaterial anatomical entity	6.31e-10	79
exocrine gland	1.05e-08	25
exocrine system	1.05e-08	25
trunk	2.10e-08	90
liver	4.04e-07	22
epithelial sac	4.04e-07	22
digestive gland	4.04e-07	22
epithelium of foregut-midgut junction	4.04e-07	22
anatomical boundary	4.04e-07	22
hepatobiliary system	4.04e-07	22
foregut-midgut junction	4.04e-07	22
hepatic diverticulum	4.04e-07	22
liver primordium	4.04e-07	22
septum transversum	4.04e-07	22
liver bud	4.04e-07	22
multi-cellular organism	5.55e-07	333

TFBS overrepresentation<b>Summary:</b>The values shown are the p-values for overrepresentation of the motif in this coexpression cluster. So a small p-value means a strong overrepresentation. <b>Analyst:</b> Michiel de Hoon <br><br>link to source data <br> Novel motifs <br>data <br><br> Jaspar motifs <br>data

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Novel motifs

JASPAR motifs

Motifs	-log10(p-value)
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