Novel motif:56

name:	motif56_GANCGT

Association to promoter expression in human samples<b>Summary:</b>Significance of the correlation with CAGE expression, human <br><b>Analyst:</b> Michiel de Hoon<br><br>link to source dataset <br>data

---

Association to promoter expression in mouse samples <b>Summary:</b>Significance of the correlation with CAGE expression, mouse <br><b>Analyst:</b> Michiel de Hoon<br><br>link to source dataset <br>data

---

GREAT analysis results for human <b>Summary:</b>Genomic Enrichment of Annotations Tool (GREAT, Nat Biotechnol. 2010 May;28(5):495-501) is used to identify, both in human and in mouse, the gene ontology terms of biological processes enriched given the predicted TFBSs, and evaluated the overlap in the top-500 gene ontology terms between human and mouse. For each novel motif, the P value for the overlap was then evaluated by calculating its relative rank with respect to this background distribution.<br>Analyst: Michiel de Hoon<br><br>link to source dataset <br>data

---

GO ID	GO Term	p-value
GO:0040040	thermosensory behavior	8.459398e-18
GO:0009992	cellular water homeostasis	4.200364e-11
GO:0071460	cellular response to cell-matrix adhesion	4.765122e-11
GO:0015696	ammonium transport	1.967270e-10
GO:0006391	transcription initiation from mitochondrial promoter	1.753194e-9
GO:0006396	RNA processing	7.770874e-9
GO:0019087	transformation of host cell by virus	1.526192e-8
GO:0043503	skeletal muscle fiber adaptation	1.567609e-8
GO:0045008	depyrimidination	2.047063e-8
GO:0009223	pyrimidine deoxyribonucleotide catabolic process	3.570864e-8
GO:0043162	ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway	3.745199e-8
GO:0016072	rRNA metabolic process	4.340556e-8
GO:0006244	pyrimidine nucleotide catabolic process	4.768567e-8
GO:0001510	RNA methylation	4.952436e-8
GO:0006364	rRNA processing	6.471669e-8
GO:0034470	ncRNA processing	6.846110e-8
GO:0071474	cellular hyperosmotic response	8.994521e-8
GO:0061032	visceral serous pericardium development	9.647180e-8
GO:0072302	negative regulation of metanephric glomerular mesangial cell proliferation	9.647180e-8
GO:0000389	nuclear mRNA 3'-splice site recognition	1.301314e-7
GO:0051452	intracellular pH reduction	1.449517e-7
GO:0034505	tooth mineralization	1.570201e-7
GO:0016090	prenol metabolic process	2.810502e-7
GO:0016032	viral reproduction	4.400649e-7
GO:0034660	ncRNA metabolic process	4.413896e-7
GO:0033169	histone H3-K9 demethylation	7.096038e-7
GO:0060923	cardiac muscle cell fate commitment	7.883383e-7
GO:0009451	RNA modification	8.219516e-7
GO:0045851	pH reduction	1.190142e-6
GO:0002528	regulation of vascular permeability involved in acute inflammatory response	1.752521e-6
GO:0060346	bone trabecula formation	2.614330e-6
GO:0044140	negative regulation of growth of symbiont on or near host surface	4.861869e-6
GO:0042727	flavin-containing compound biosynthetic process	4.982635e-6
GO:0002536	respiratory burst involved in inflammatory response	5.258067e-6
GO:0051549	positive regulation of keratinocyte migration	5.486153e-6
GO:0051645	Golgi localization	5.757535e-6
GO:0001957	intramembranous ossification	6.061089e-6
GO:0006491	N-glycan processing	6.244802e-6
GO:0042423	catecholamine biosynthetic process	8.159477e-6
GO:0000185	activation of MAPKKK activity	8.424684e-6
GO:0016577	histone demethylation	9.035695e-6
GO:0042558	pteridine-containing compound metabolic process	9.581813e-6
GO:0042416	dopamine biosynthetic process	1.076992e-5
GO:0051725	protein de-ADP-ribosylation	1.187972e-5
GO:0042254	ribosome biogenesis	1.191914e-5
GO:0072166	posterior mesonephric tubule development	1.253621e-5
GO:0035507	regulation of myosin-light-chain-phosphatase activity	1.345029e-5
GO:0033145	positive regulation of steroid hormone receptor signaling pathway	1.360302e-5
GO:0006882	cellular zinc ion homeostasis	1.690297e-5
GO:0002635	negative regulation of germinal center formation	1.807814e-5
GO:0071318	cellular response to ATP	1.986301e-5
GO:0008078	mesodermal cell migration	1.986301e-5
GO:0006285	base-excision repair, AP site formation	2.139062e-5
GO:0071404	cellular response to low-density lipoprotein particle stimulus	2.156522e-5
GO:0046856	phosphatidylinositol dephosphorylation	2.258110e-5
GO:0006352	transcription initiation, DNA-dependent	2.638207e-5
GO:0042851	L-alanine metabolic process	2.840920e-5
GO:0006482	protein demethylation	3.204721e-5
GO:0051453	regulation of intracellular pH	3.260290e-5
GO:0009219	pyrimidine deoxyribonucleotide metabolic process	3.580995e-5
GO:0070534	protein K63-linked ubiquitination	3.636567e-5
GO:0045358	negative regulation of interferon-beta biosynthetic process	3.735729e-5
GO:0010509	polyamine homeostasis	3.735729e-5
GO:0022613	ribonucleoprotein complex biogenesis	3.776834e-5
GO:0033148	positive regulation of estrogen receptor signaling pathway	4.033882e-5
GO:0006412	translation	4.037232e-5
GO:0008298	intracellular mRNA localization	4.413462e-5
GO:0072301	regulation of metanephric glomerular mesangial cell proliferation	4.692509e-5
GO:0006760	folic acid-containing compound metabolic process	4.970666e-5
GO:0042998	positive regulation of Golgi to plasma membrane protein transport	5.145410e-5
GO:0061157	mRNA destabilization	5.145410e-5
GO:0010609	posttranscriptional regulation of gene expression by mRNA localization	5.145410e-5
GO:0042726	flavin-containing compound metabolic process	5.391103e-5
GO:0016191	synaptic vesicle uncoating	5.743839e-5
GO:0050690	regulation of defense response to virus by virus	5.823954e-5
GO:0033146	regulation of estrogen receptor signaling pathway	5.967409e-5
GO:0000413	protein peptidyl-prolyl isomerization	7.036182e-5
GO:0006413	translational initiation	7.112110e-5
GO:0045338	farnesyl diphosphate metabolic process	7.222632e-5
GO:0030037	actin filament reorganization involved in cell cycle	7.485870e-5
GO:0000296	spermine transport	7.485870e-5
GO:0005978	glycogen biosynthetic process	7.500140e-5
GO:0071402	cellular response to lipoprotein particle stimulus	7.501695e-5
GO:0006367	transcription initiation from RNA polymerase II promoter	7.759353e-5
GO:0071218	cellular response to misfolded protein	8.215762e-5
GO:0008033	tRNA processing	8.620533e-5
GO:0014829	vascular smooth muscle contraction	8.797245e-5
GO:0007130	synaptonemal complex assembly	8.905537e-5
GO:0032108	negative regulation of response to nutrient levels	8.995404e-5
GO:0071470	cellular response to osmotic stress	8.995404e-5
GO:0022038	corpus callosum development	9.271884e-5
GO:0071843	cellular component biogenesis at cellular level	9.313039e-5
GO:0034445	negative regulation of plasma lipoprotein particle oxidation	9.408427e-5
GO:0009231	riboflavin biosynthetic process	9.666165e-5
GO:0033687	osteoblast proliferation	1.016292e-4
GO:0045217	cell-cell junction maintenance	1.080265e-4
GO:0051591	response to cAMP	1.196524e-4
GO:0045838	positive regulation of membrane potential	1.242904e-4
GO:0042310	vasoconstriction	1.264437e-4
GO:0051131	chaperone-mediated protein complex assembly	1.293278e-4
GO:0035356	cellular triglyceride homeostasis	1.383481e-4
GO:0018277	protein deamination	1.383481e-4
GO:0070979	protein K11-linked ubiquitination	1.436765e-4
GO:0060033	anatomical structure regression	1.493041e-4
GO:0071956	cellular component maintenance at cellular level	1.560020e-4
GO:0018208	peptidyl-proline modification	1.635675e-4
GO:0060575	intestinal epithelial cell differentiation	1.664073e-4
GO:0051066	dihydrobiopterin metabolic process	1.716727e-4
GO:0045820	negative regulation of glycolysis	1.751760e-4
GO:0022007	convergent extension involved in neural plate elongation	1.774522e-4
GO:0090035	positive regulation of cellular chaperone-mediated protein complex assembly	1.838063e-4
GO:0048260	positive regulation of receptor-mediated endocytosis	1.913846e-4
GO:0031081	nuclear pore distribution	1.998344e-4
GO:0018192	enzyme active site formation via L-cysteine persulfide	1.998344e-4
GO:0001682	tRNA 5'-leader removal	1.998344e-4
GO:0016078	tRNA catabolic process	1.998344e-4
GO:0043501	skeletal muscle adaptation	2.067909e-4
GO:2000466	negative regulation of glycogen (starch) synthase activity	2.131992e-4
GO:0044243	multicellular organismal catabolic process	2.291402e-4
GO:0006359	regulation of transcription from RNA polymerase III promoter	2.348772e-4
GO:0042420	dopamine catabolic process	2.412336e-4
GO:0090141	positive regulation of mitochondrial fission	2.438034e-4
GO:0055094	response to lipoprotein stimulus	2.522100e-4
GO:0055069	zinc ion homeostasis	2.561058e-4
GO:0006515	misfolded or incompletely synthesized protein catabolic process	2.572591e-4
GO:0033108	mitochondrial respiratory chain complex assembly	2.702377e-4
GO:0006414	translational elongation	2.742436e-4
GO:0070535	histone H2A K63-linked ubiquitination	2.745307e-4
GO:0000046	autophagic vacuole fusion	2.745307e-4
GO:0035752	lysosomal lumen pH elevation	2.745307e-4
GO:0001575	globoside metabolic process	2.745307e-4
GO:0033342	negative regulation of collagen binding	2.745307e-4
GO:0006457	protein folding	2.830521e-4
GO:0032581	ER-dependent peroxisome organization	2.866905e-4
GO:0010266	response to vitamin B1	2.870330e-4
GO:0071316	cellular response to nicotine	2.930382e-4
GO:0010866	regulation of triglyceride biosynthetic process	2.966240e-4
GO:0034453	microtubule anchoring	3.053735e-4
GO:0090370	negative regulation of cholesterol efflux	3.152049e-4
GO:0035873	lactate transmembrane transport	3.152049e-4
GO:0006546	glycine catabolic process	3.566619e-4
GO:0090207	regulation of triglyceride metabolic process	3.593304e-4
GO:0060738	epithelial-mesenchymal signaling involved in prostate gland development	3.634489e-4
GO:0006390	transcription from mitochondrial promoter	3.634489e-4
GO:0072376	protein activation cascade	3.664417e-4
GO:0030277	maintenance of gastrointestinal epithelium	3.748756e-4
GO:0034063	stress granule assembly	3.828824e-4
GO:0070988	demethylation	3.891943e-4
GO:0006220	pyrimidine nucleotide metabolic process	4.241135e-4
GO:0006368	transcription elongation from RNA polymerase II promoter	4.288423e-4
GO:0030574	collagen catabolic process	4.377146e-4
GO:0006600	creatine metabolic process	4.450823e-4
GO:0016557	peroxisome membrane biogenesis	4.469159e-4
GO:0044314	protein K27-linked ubiquitination	4.583069e-4
GO:0035269	protein O-linked mannosylation	4.583069e-4
GO:0044342	type B pancreatic cell proliferation	4.619930e-4
GO:0010918	positive regulation of mitochondrial membrane potential	4.619930e-4
GO:0030225	macrophage differentiation	4.649234e-4
GO:0000072	M phase specific microtubule process	5.003046e-4
GO:0006956	complement activation	5.023622e-4
GO:0060134	prepulse inhibition	5.098999e-4
GO:0009264	deoxyribonucleotide catabolic process	5.269051e-4
GO:0090281	negative regulation of calcium ion import	5.278050e-4
GO:0071584	negative regulation of zinc ion import	5.278050e-4
GO:0006584	catecholamine metabolic process	5.411242e-4
GO:0006303	double-strand break repair via nonhomologous end joining	5.449397e-4
GO:0060988	lipid tube assembly	5.840658e-4
GO:0032235	negative regulation of calcium ion transport via store-operated calcium channel activity	5.852085e-4
GO:0030539	male genitalia development	6.007985e-4
GO:0030641	regulation of cellular pH	6.089754e-4
GO:0008049	male courtship behavior	6.238286e-4
GO:0043048	dolichyl monophosphate biosynthetic process	6.374169e-4
GO:0010467	gene expression	6.508504e-4
GO:0046208	spermine catabolic process	6.519430e-4
GO:0009712	catechol-containing compound metabolic process	6.648835e-4
GO:0005980	glycogen catabolic process	6.654252e-4
GO:0051097	negative regulation of helicase activity	6.674419e-4
GO:0002071	glandular epithelial cell maturation	6.674419e-4
GO:0019637	organophosphate metabolic process	6.917340e-4
GO:0006680	glucosylceramide catabolic process	7.014437e-4
GO:0002065	columnar/cuboidal epithelial cell differentiation	7.518325e-4
GO:0009311	oligosaccharide metabolic process	7.648710e-4
GO:0042149	cellular response to glucose starvation	7.969110e-4
GO:0010677	negative regulation of cellular carbohydrate metabolic process	8.063263e-4
GO:2000210	positive regulation of anoikis	8.121339e-4
GO:0007042	lysosomal lumen acidification	8.121339e-4
GO:0090140	regulation of mitochondrial fission	8.140629e-4
GO:0031167	rRNA methylation	8.140629e-4
GO:0050748	negative regulation of lipoprotein metabolic process	8.409335e-4
GO:0071557	histone H3-K27 demethylation	8.433150e-4
GO:0035574	histone H4-K20 demethylation	8.433150e-4
GO:0021819	layer formation in cerebral cortex	8.433150e-4
GO:0006399	tRNA metabolic process	8.458267e-4
GO:0051532	regulation of NFAT protein import into nucleus	8.676753e-4
GO:0007021	tubulin complex assembly	8.690576e-4
GO:0060351	cartilage development involved in endochondral bone morphogenesis	8.854096e-4
GO:0019348	dolichol metabolic process	9.091312e-4
GO:0060743	epithelial cell maturation involved in prostate gland development	9.357752e-4
GO:0016242	negative regulation of macroautophagy	9.369582e-4
GO:0061302	smooth muscle cell-matrix adhesion	9.369582e-4
GO:0035094	response to nicotine	9.820936e-4
GO:0051798	positive regulation of hair follicle development	9.848058e-4
GO:0046416	D-amino acid metabolic process	1.007580e-3
GO:0010960	magnesium ion homeostasis	1.007580e-3
GO:0006505	GPI anchor metabolic process	1.038779e-3
GO:0046931	pore complex assembly	1.041377e-3
GO:0071585	detoxification of cadmium ion	1.064642e-3
GO:0050689	negative regulation of defense response to virus by host	1.071328e-3
GO:0035814	negative regulation of renal sodium excretion	1.088887e-3
GO:0007509	mesoderm migration involved in gastrulation	1.166283e-3
GO:0001958	endochondral ossification	1.197681e-3
GO:0014888	striated muscle adaptation	1.205122e-3
GO:0010836	negative regulation of protein ADP-ribosylation	1.247580e-3
GO:0060830	ciliary receptor clustering involved in smoothened signaling pathway	1.285736e-3
GO:0072285	mesenchymal to epithelial transition involved in metanephric renal vesicle formation	1.285736e-3
GO:0060248	detection of cell density by contact stimulus involved in contact inhibition	1.285736e-3
GO:0007371	ventral midline determination	1.285736e-3
GO:0044236	multicellular organismal metabolic process	1.302503e-3
GO:0032107	regulation of response to nutrient levels	1.308093e-3
GO:0060911	cardiac cell fate commitment	1.365163e-3
GO:0023019	signal transduction involved in regulation of gene expression	1.372482e-3
GO:0046839	phospholipid dephosphorylation	1.374110e-3
GO:0060350	endochondral bone morphogenesis	1.461375e-3
GO:0009251	glucan catabolic process	1.465571e-3
GO:0044247	cellular polysaccharide catabolic process	1.465571e-3
GO:0050883	musculoskeletal movement, spinal reflex action	1.484392e-3
GO:0071423	malate transmembrane transport	1.484392e-3
GO:0015709	thiosulfate transport	1.484392e-3
GO:0046655	folic acid metabolic process	1.522203e-3
GO:0007595	lactation	1.532561e-3
GO:0070173	regulation of enamel mineralization	1.557943e-3
GO:0034766	negative regulation of ion transmembrane transport	1.559793e-3
GO:0016598	protein arginylation	1.559793e-3
GO:0002508	central tolerance induction	1.559793e-3
GO:0002897	positive regulation of central B cell tolerance induction	1.559793e-3
GO:0048144	fibroblast proliferation	1.582911e-3
GO:0072369	regulation of lipid transport by positive regulation of transcription from RNA polymerase II promoter	1.599097e-3
GO:0046654	tetrahydrofolate biosynthetic process	1.599097e-3
GO:0007020	microtubule nucleation	1.619683e-3
GO:0033133	positive regulation of glucokinase activity	1.623167e-3
GO:0007589	body fluid secretion	1.631727e-3
GO:0045776	negative regulation of blood pressure	1.672448e-3
GO:0009443	pyridoxal 5'-phosphate salvage	1.675237e-3
GO:0060684	epithelial-mesenchymal cell signaling	1.682296e-3
GO:0042574	retinal metabolic process	1.691694e-3
GO:2000195	negative regulation of female gonad development	1.715938e-3
GO:0051788	response to misfolded protein	1.840388e-3
GO:0070208	protein heterotrimerization	1.840979e-3
GO:0030422	production of siRNA involved in RNA interference	1.853427e-3
GO:0006353	transcription termination, DNA-dependent	1.855436e-3
GO:0008380	RNA splicing	1.902716e-3
GO:0009957	epidermal cell fate specification	1.919867e-3
GO:0061048	negative regulation of branching involved in lung morphogenesis	1.946279e-3
GO:0034442	regulation of lipoprotein oxidation	1.959936e-3
GO:0002069	columnar/cuboidal epithelial cell maturation	1.959936e-3
GO:0051385	response to mineralocorticoid stimulus	1.976573e-3
GO:0006982	response to lipid hydroperoxide	1.979509e-3
GO:0001522	pseudouridine synthesis	1.995975e-3
GO:2000194	regulation of female gonad development	2.003253e-3
GO:0010889	regulation of sequestering of triglyceride	2.036114e-3
GO:0090205	positive regulation of cholesterol metabolic process	2.067424e-3
GO:2000249	regulation of actin cytoskeleton reorganization	2.071262e-3
GO:0021591	ventricular system development	2.079451e-3
GO:0045218	zonula adherens maintenance	2.157255e-3
GO:0001983	baroreceptor response to increased systemic arterial blood pressure	2.187917e-3
GO:0014878	response to electrical stimulus involved in regulation of muscle adaptation	2.205324e-3
GO:0051412	response to corticosterone stimulus	2.205915e-3
GO:0046929	negative regulation of neurotransmitter secretion	2.220251e-3
GO:0034551	mitochondrial respiratory chain complex III assembly	2.220630e-3
GO:0006867	asparagine transport	2.220630e-3
GO:0006711	estrogen catabolic process	2.220630e-3
GO:0000088	mitotic prophase	2.220630e-3
GO:0032836	glomerular basement membrane development	2.272205e-3
GO:0090344	negative regulation of cell aging	2.276865e-3
GO:0043687	post-translational protein modification	2.363260e-3
GO:0071539	protein localization to centrosome	2.391614e-3
GO:0060375	regulation of mast cell differentiation	2.391614e-3
GO:0006438	valyl-tRNA aminoacylation	2.408707e-3
GO:0050908	detection of light stimulus involved in visual perception	2.447748e-3
GO:0051454	intracellular pH elevation	2.462757e-3
GO:0006489	dolichyl diphosphate biosynthetic process	2.462757e-3
GO:0060741	prostate gland stromal morphogenesis	2.470646e-3
GO:0048014	Tie receptor signaling pathway	2.470646e-3
GO:0001970	positive regulation of activation of membrane attack complex	2.519058e-3
GO:0006544	glycine metabolic process	2.519640e-3
GO:0033692	cellular polysaccharide biosynthetic process	2.600129e-3
GO:0033143	regulation of steroid hormone receptor signaling pathway	2.690971e-3
GO:0006958	complement activation, classical pathway	2.748737e-3
GO:0043241	protein complex disassembly	2.791634e-3
GO:0000726	non-recombinational repair	2.820053e-3
GO:0042559	pteridine-containing compound biosynthetic process	2.839273e-3
GO:0042417	dopamine metabolic process	2.860811e-3
GO:0005977	glycogen metabolic process	2.901587e-3
GO:0019276	UDP-N-acetylgalactosamine metabolic process	2.907576e-3
GO:0006562	proline catabolic process	2.907576e-3
GO:0070192	chromosome organization involved in meiosis	2.939995e-3
GO:0090042	tubulin deacetylation	2.981519e-3
GO:0070846	Hsp90 deacetylation	2.981519e-3
GO:0003094	glomerular filtration	2.981519e-3
GO:0042305	specification of segmental identity, mandibular segment	2.981519e-3
GO:0021592	fourth ventricle development	3.015098e-3
GO:0043089	positive regulation of Cdc42 GTPase activity	3.048157e-3
GO:0034436	glycoprotein transport	3.050495e-3
GO:0009720	detection of hormone stimulus	3.050495e-3
GO:0006598	polyamine catabolic process	3.050495e-3
GO:0090234	regulation of kinetochore assembly	3.085933e-3
GO:0090169	regulation of spindle assembly	3.085933e-3
GO:0008299	isoprenoid biosynthetic process	3.089033e-3
GO:0071577	zinc ion transmembrane transport	3.117547e-3
GO:0010669	epithelial structure maintenance	3.135084e-3
GO:0060343	trabecula formation	3.159938e-3
GO:0090263	positive regulation of canonical Wnt receptor signaling pathway	3.184234e-3
GO:0007131	reciprocal meiotic recombination	3.207755e-3
GO:0055078	sodium ion homeostasis	3.357096e-3
GO:0042989	sequestering of actin monomers	3.397127e-3
GO:0009235	cobalamin metabolic process	3.450781e-3
GO:2000009	negative regulation of protein localization at cell surface	3.457538e-3
GO:0031668	cellular response to extracellular stimulus	3.460608e-3
GO:0000154	rRNA modification	3.654464e-3
GO:0032915	positive regulation of transforming growth factor beta2 production	3.671622e-3
GO:0007100	mitotic centrosome separation	3.671622e-3
GO:0030177	positive regulation of Wnt receptor signaling pathway	3.693278e-3
GO:0010039	response to iron ion	3.721161e-3
GO:0032792	negative regulation of CREB transcription factor activity	3.726514e-3
GO:0046855	inositol phosphate dephosphorylation	3.763489e-3
GO:0061383	trabecula morphogenesis	3.802044e-3
GO:0007141	male meiosis I	3.906099e-3
GO:0008654	phospholipid biosynthetic process	3.966624e-3
GO:0006678	glucosylceramide metabolic process	3.994748e-3
GO:0071545	inositol phosphate catabolic process	4.023980e-3
GO:0071897	DNA biosynthetic process	4.148785e-3
GO:0006644	phospholipid metabolic process	4.158591e-3
GO:0055014	atrial cardiac muscle cell development	4.172392e-3
GO:0043088	regulation of Cdc42 GTPase activity	4.187425e-3
GO:0007006	mitochondrial membrane organization	4.203898e-3
GO:0006103	2-oxoglutarate metabolic process	4.234652e-3
GO:0072393	microtubule anchoring at microtubule organizing center	4.517260e-3
GO:0042053	regulation of dopamine metabolic process	4.553846e-3
GO:0060179	male mating behavior	4.554489e-3
GO:0006073	cellular glucan metabolic process	4.554542e-3
GO:0010458	exit from mitosis	4.634264e-3
GO:0055098	response to low-density lipoprotein particle stimulus	4.650743e-3
GO:0006369	termination of RNA polymerase II transcription	4.712183e-3
GO:0001885	endothelial cell development	4.719495e-3
GO:0045919	positive regulation of cytolysis	4.740630e-3
GO:0023021	termination of signal transduction	4.740630e-3
GO:0034421	post-translational protein acetylation	4.759524e-3
GO:0008215	spermine metabolic process	4.806616e-3
GO:0014916	regulation of lung blood pressure	4.937796e-3
GO:0070076	histone lysine demethylation	4.969015e-3
GO:0046902	regulation of mitochondrial membrane permeability	5.102478e-3
GO:0072367	regulation of lipid transport by regulation of transcription from RNA polymerase II promoter	5.265869e-3
GO:0061298	retina vasculature development in camera-type eye	5.274367e-3
GO:0030259	lipid glycosylation	5.274367e-3
GO:0010888	negative regulation of lipid storage	5.275210e-3
GO:0042424	catecholamine catabolic process	5.311225e-3
GO:0001978	regulation of systemic arterial blood pressure by carotid sinus baroreceptor feedback	5.311225e-3
GO:0034120	positive regulation of erythrocyte aggregation	5.408919e-3
GO:0030488	tRNA methylation	5.408919e-3
GO:0010070	zygote asymmetric cell division	5.498330e-3
GO:0035790	platelet-derived growth factor receptor-alpha signaling pathway	5.498330e-3
GO:0006939	smooth muscle contraction	5.531304e-3
GO:0010954	positive regulation of protein processing	5.710786e-3
GO:0009163	nucleoside biosynthetic process	5.757500e-3
GO:2000074	regulation of type B pancreatic cell development	5.780857e-3
GO:0000239	pachytene	5.854925e-3
GO:0070105	positive regulation of interleukin-6-mediated signaling pathway	5.863239e-3
GO:0031284	positive regulation of guanylate cyclase activity	5.863239e-3
GO:0035026	leading edge cell differentiation	5.863239e-3
GO:0072224	metanephric glomerulus development	5.921943e-3
GO:0002121	inter-male aggressive behavior	5.945288e-3
GO:0032963	collagen metabolic process	5.975104e-3
GO:0051299	centrosome separation	5.989027e-3
GO:0061028	establishment of endothelial barrier	6.088721e-3
GO:0046653	tetrahydrofolate metabolic process	6.128019e-3
GO:0050434	positive regulation of viral transcription	6.480274e-3
GO:0090224	regulation of spindle organization	6.515781e-3
GO:0044259	multicellular organismal macromolecule metabolic process	6.516935e-3
GO:0042069	regulation of catecholamine metabolic process	6.525283e-3
GO:0016074	snoRNA metabolic process	6.545148e-3
GO:0002238	response to molecule of fungal origin	6.757164e-3
GO:0045684	positive regulation of epidermis development	6.771939e-3
GO:0042059	negative regulation of epidermal growth factor receptor signaling pathway	6.815906e-3
GO:0006783	heme biosynthetic process	6.876588e-3
GO:0006446	regulation of translational initiation	6.987616e-3
GO:0060376	positive regulation of mast cell differentiation	7.180881e-3
GO:0035229	positive regulation of glutamate-cysteine ligase activity	7.180881e-3
GO:0070179	D-serine biosynthetic process	7.235818e-3
GO:0006713	glucocorticoid catabolic process	7.235818e-3
GO:0046629	gamma-delta T cell activation	7.235818e-3
GO:0046952	ketone body catabolic process	7.287246e-3
GO:0031643	positive regulation of myelination	7.287246e-3
GO:0035418	protein localization to synapse	7.402258e-3
GO:0097070	ductus arteriosus closure	7.405612e-3
GO:0072366	regulation of cellular ketone metabolic process by positive regulation of transcription from RNA polymerase II promoter	7.454640e-3
GO:0001986	negative regulation of the force of heart contraction involved in baroreceptor response to increased systemic arterial blood pressure	7.454640e-3
GO:0072363	regulation of glycolysis by positive regulation of transcription from RNA polymerase II promoter	7.454640e-3
GO:0051660	establishment of centrosome localization	7.613276e-3
GO:0071335	hair follicle cell proliferation	7.613276e-3
GO:0048178	negative regulation of hepatocyte growth factor biosynthetic process	7.613276e-3
GO:0032290	peripheral nervous system myelin formation	7.613276e-3
GO:0021540	corpus callosum morphogenesis	7.613276e-3
GO:0033131	regulation of glucokinase activity	7.679649e-3
GO:0032096	negative regulation of response to food	7.858786e-3
GO:0071347	cellular response to interleukin-1	7.876596e-3
GO:0030004	cellular monovalent inorganic cation homeostasis	7.893492e-3
GO:0006281	DNA repair	7.944228e-3
GO:0046318	negative regulation of glucosylceramide biosynthetic process	7.960198e-3
GO:0072333	signal transduction by p53 class mediator resulting in induction of anoikis	8.047586e-3
GO:0072124	regulation of glomerular mesangial cell proliferation	8.104123e-3
GO:0002070	epithelial cell maturation	8.177393e-3
GO:0010812	negative regulation of cell-substrate adhesion	8.368898e-3
GO:0007228	positive regulation of hh target transcription factor activity	8.421595e-3
GO:0006388	tRNA splicing, via endonucleolytic cleavage and ligation	8.421595e-3
GO:0070682	proteasome regulatory particle assembly	8.497839e-3
GO:0015878	biotin transport	8.497839e-3
GO:0015887	pantothenate transmembrane transport	8.497839e-3
GO:0060742	epithelial cell differentiation involved in prostate gland development	8.682559e-3
GO:0006189	'de novo' IMP biosynthetic process	8.714229e-3
GO:0006488	dolichol-linked oligosaccharide biosynthetic process	8.720418e-3
GO:0051956	negative regulation of amino acid transport	8.863571e-3
GO:0006072	glycerol-3-phosphate metabolic process	8.863571e-3
GO:0003009	skeletal muscle contraction	8.984152e-3
GO:0051488	activation of anaphase-promoting complex activity	9.016167e-3
GO:0045714	regulation of low-density lipoprotein particle receptor biosynthetic process	9.016167e-3
GO:0014044	Schwann cell development	9.016522e-3
GO:0044260	cellular macromolecule metabolic process	9.036346e-3
GO:0042364	water-soluble vitamin biosynthetic process	9.040804e-3
GO:0042823	pyridoxal phosphate biosynthetic process	9.184839e-3
GO:0071415	cellular response to purine-containing compound	9.229899e-3
GO:0060356	leucine import	9.229899e-3
GO:0033299	secretion of lysosomal enzymes	9.341597e-3
GO:0003289	atrial septum primum morphogenesis	9.350822e-3
GO:0016926	protein desumoylation	9.366377e-3
GO:0010934	macrophage cytokine production	9.366377e-3
GO:0021670	lateral ventricle development	9.381933e-3
GO:0071168	protein localization to chromatin	9.387732e-3
GO:0010890	positive regulation of sequestering of triglyceride	9.387732e-3
GO:0070193	synaptonemal complex organization	9.509853e-3
GO:0009394	2'-deoxyribonucleotide metabolic process	9.561728e-3
GO:0042401	cellular biogenic amine biosynthetic process	9.645253e-3
GO:0006354	transcription elongation, DNA-dependent	9.663296e-3
GO:0051926	negative regulation of calcium ion transport	9.698239e-3
GO:0009267	cellular response to starvation	9.833332e-3
GO:0001964	startle response	9.879976e-3
GO:0072298	regulation of metanephric glomerulus development	9.899817e-3
GO:0032008	positive regulation of TOR signaling cascade	9.968200e-3
GO:0060528	secretory columnal luminar epithelial cell differentiation involved in prostate glandular acinus development	9.990907e-3
GO:0032922	circadian regulation of gene expression	1.005507e-2
GO:0045542	positive regulation of cholesterol biosynthetic process	1.005507e-2
GO:0007017	microtubule-based process	1.017751e-2
GO:0006556	S-adenosylmethionine biosynthetic process	1.019317e-2
GO:0051324	prophase	1.021741e-2
GO:0032741	positive regulation of interleukin-18 production	1.032657e-2
GO:0070562	regulation of vitamin D receptor signaling pathway	1.067512e-2
GO:0002922	positive regulation of humoral immune response	1.082827e-2
GO:0007612	learning	1.088200e-2
GO:0048537	mucosal-associated lymphoid tissue development	1.089406e-2
GO:0048312	intracellular distribution of mitochondria	1.107624e-2
GO:0042594	response to starvation	1.110988e-2
GO:0070885	negative regulation of calcineurin-NFAT signaling pathway	1.120886e-2
GO:0007129	synapsis	1.136064e-2
GO:0002891	positive regulation of immunoglobulin mediated immune response	1.136758e-2
GO:0071034	CUT catabolic process	1.137793e-2
GO:2000077	negative regulation of type B pancreatic cell development	1.137793e-2
GO:0044356	clearance of foreign intracellular DNA by conversion of DNA cytidine to uridine	1.137793e-2
GO:0010994	free ubiquitin chain polymerization	1.137793e-2
GO:0007250	activation of NF-kappaB-inducing kinase activity	1.143315e-2
GO:0000086	G2/M transition of mitotic cell cycle	1.145193e-2
GO:0051182	coenzyme transport	1.158275e-2
GO:0035774	positive regulation of insulin secretion involved in cellular response to glucose stimulus	1.169125e-2
GO:0034441	plasma lipoprotein particle oxidation	1.169125e-2
GO:0035967	cellular response to topologically incorrect protein	1.177923e-2
GO:0031915	positive regulation of synaptic plasticity	1.185044e-2
GO:0051534	negative regulation of NFAT protein import into nucleus	1.186465e-2
GO:0006450	regulation of translational fidelity	1.211889e-2
GO:0046548	retinal rod cell development	1.217206e-2
GO:0045945	positive regulation of transcription from RNA polymerase III promoter	1.231192e-2
GO:0018205	peptidyl-lysine modification	1.235944e-2
GO:0045588	positive regulation of gamma-delta T cell differentiation	1.249735e-2
GO:0010626	negative regulation of Schwann cell proliferation	1.253103e-2
GO:0006120	mitochondrial electron transport, NADH to ubiquinone	1.255663e-2
GO:2000001	regulation of DNA damage checkpoint	1.276965e-2
GO:0071169	establishment of protein localization to chromatin	1.298724e-2
GO:0018364	peptidyl-glutamine methylation	1.298724e-2
GO:0051955	regulation of amino acid transport	1.299639e-2
GO:0009396	folic acid-containing compound biosynthetic process	1.299639e-2
GO:2000311	regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor activity	1.305308e-2
GO:0014037	Schwann cell differentiation	1.306492e-2
GO:0032648	regulation of interferon-beta production	1.307971e-2
GO:0060823	canonical Wnt receptor signaling pathway involved in neural plate anterior/posterior pattern formation	1.336924e-2
GO:0060770	negative regulation of epithelial cell proliferation involved in prostate gland development	1.339837e-2
GO:0019985	translesion synthesis	1.339966e-2
GO:0006447	regulation of translational initiation by iron	1.339966e-2
GO:0060768	regulation of epithelial cell proliferation involved in prostate gland development	1.357977e-2
GO:0010310	regulation of hydrogen peroxide metabolic process	1.358319e-2
GO:0006301	postreplication repair	1.359439e-2
GO:0048712	negative regulation of astrocyte differentiation	1.373906e-2
GO:2000209	regulation of anoikis	1.384638e-2
GO:0060464	lung lobe formation	1.389821e-2

GREAT analysis results for mouseGenomic Enrichment of Annotations Tool (GREAT, Nat Biotechnol. 2010 May;28(5):495-501) is used to identify, both in human and in mouse, the gene ontology terms of biological processes enriched given the predicted TFBSs, and evaluated the overlap in the top-500 gene ontology terms between human and mouse. For each novel motif, the P value for the overlap was then evaluated by calculating its relative rank with respect to this background distribution.<br>Analyst: Michiel de Hoon <br><br>link to source dataset <br>data

---

GO ID	GO Term	p-value
GO:0034660	ncRNA metabolic process	3.513354e-13
GO:0070179	D-serine biosynthetic process	1.344938e-9
GO:0046092	deoxycytidine metabolic process	2.319410e-9
GO:0046125	pyrimidine deoxyribonucleoside metabolic process	3.610692e-9
GO:0006396	RNA processing	7.211250e-9
GO:0015876	acetyl-CoA transport	1.037397e-8
GO:0035507	regulation of myosin-light-chain-phosphatase activity	1.288285e-8
GO:0046038	GMP catabolic process	6.908640e-8
GO:0032264	IMP salvage	6.908640e-8
GO:0006178	guanine salvage	6.908640e-8
GO:0018192	enzyme active site formation via L-cysteine persulfide	6.908640e-8
GO:0032263	GMP salvage	6.908640e-8
GO:0097029	mature dendritic cell differentiation	9.163527e-8
GO:0006168	adenine salvage	9.274065e-8
GO:0043517	positive regulation of DNA damage response, signal transduction by p53 class mediator	1.510903e-7
GO:0006413	translational initiation	1.659927e-7
GO:0000910	cytokinesis	1.763998e-7
GO:0000956	nuclear-transcribed mRNA catabolic process	2.023164e-7
GO:0016072	rRNA metabolic process	2.097748e-7
GO:0016926	protein desumoylation	2.114559e-7
GO:0071044	histone mRNA catabolic process	2.784500e-7
GO:0006364	rRNA processing	3.187692e-7
GO:0043096	purine base salvage	3.441550e-7
GO:0034470	ncRNA processing	3.802093e-7
GO:0046416	D-amino acid metabolic process	4.051146e-7
GO:0006975	DNA damage induced protein phosphorylation	4.118154e-7
GO:0042396	phosphagen biosynthetic process	4.824685e-7
GO:0009051	pentose-phosphate shunt, oxidative branch	9.338415e-7
GO:0008334	histone mRNA metabolic process	1.006776e-6
GO:0043103	hypoxanthine salvage	1.030416e-6
GO:0032261	purine nucleotide salvage	1.030416e-6
GO:0045884	regulation of survival gene product expression	1.470474e-6
GO:0090304	nucleic acid metabolic process	1.581065e-6
GO:0006402	mRNA catabolic process	2.368182e-6
GO:0009113	purine base biosynthetic process	2.406231e-6
GO:0006188	IMP biosynthetic process	3.111868e-6
GO:0010454	negative regulation of cell fate commitment	3.347027e-6
GO:0046129	purine ribonucleoside biosynthetic process	3.505112e-6
GO:0042660	positive regulation of cell fate specification	4.107492e-6
GO:0060307	regulation of ventricular cardiomyocyte membrane repolarization	4.376703e-6
GO:0060299	negative regulation of sarcomere organization	4.376703e-6
GO:0010467	gene expression	4.776172e-6
GO:0045964	positive regulation of dopamine metabolic process	5.086967e-6
GO:0042278	purine nucleoside metabolic process	5.237265e-6
GO:0006139	nucleobase-containing compound metabolic process	5.252109e-6
GO:0002663	positive regulation of B cell tolerance induction	5.559956e-6
GO:0043558	regulation of translational initiation in response to stress	5.797944e-6
GO:0000279	M phase	5.999014e-6
GO:0006020	inositol metabolic process	6.640304e-6
GO:0051583	dopamine uptake	7.902075e-6
GO:0032416	negative regulation of sodium:hydrogen antiporter activity	9.149336e-6
GO:0006399	tRNA metabolic process	1.011517e-5
GO:0035269	protein O-linked mannosylation	1.090822e-5
GO:0009996	negative regulation of cell fate specification	1.215555e-5
GO:0042254	ribosome biogenesis	1.296039e-5
GO:0060658	nipple morphogenesis	1.334524e-5
GO:0033120	positive regulation of RNA splicing	1.383367e-5
GO:0046548	retinal rod cell development	1.430180e-5
GO:0006412	translation	1.508465e-5
GO:0006401	RNA catabolic process	1.632935e-5
GO:0022613	ribonucleoprotein complex biogenesis	2.017387e-5
GO:0071034	CUT catabolic process	2.167464e-5
GO:0055078	sodium ion homeostasis	2.195571e-5
GO:0034587	piRNA metabolic process	2.413155e-5
GO:0046314	phosphocreatine biosynthetic process	2.473011e-5
GO:0034635	glutathione transport	2.473011e-5
GO:0006177	GMP biosynthetic process	2.586409e-5
GO:0032859	activation of Ral GTPase activity	2.601378e-5
GO:0019673	GDP-mannose metabolic process	2.725984e-5
GO:0033240	positive regulation of cellular amine metabolic process	2.749805e-5
GO:0009116	nucleoside metabolic process	2.900237e-5
GO:0046128	purine ribonucleoside metabolic process	2.907631e-5
GO:0048047	mating behavior, sex discrimination	2.961094e-5
GO:0002124	territorial aggressive behavior	2.961094e-5
GO:0006281	DNA repair	3.140680e-5
GO:0051301	cell division	3.436252e-5
GO:0043526	neuroprotection	3.564953e-5
GO:0072608	interleukin-10 secretion	3.669991e-5
GO:0072643	interferon-gamma secretion	3.669991e-5
GO:0090198	negative regulation of chemokine secretion	3.669991e-5
GO:0070963	positive regulation of neutrophil mediated killing of gram-negative bacterium	3.669991e-5
GO:0048291	isotype switching to IgG isotypes	3.669991e-5
GO:0035926	chemokine (C-C motif) ligand 2 secretion	3.669991e-5
GO:0002368	B cell cytokine production	3.669991e-5
GO:0043311	positive regulation of eosinophil degranulation	3.669991e-5
GO:0048143	astrocyte activation	3.951034e-5
GO:0042866	pyruvate biosynthetic process	4.041581e-5
GO:0071843	cellular component biogenesis at cellular level	4.400770e-5
GO:0061351	neural precursor cell proliferation	4.833600e-5
GO:0002924	negative regulation of humoral immune response mediated by circulating immunoglobulin	5.180202e-5
GO:0090083	regulation of inclusion body assembly	5.508693e-5
GO:0032057	negative regulation of translational initiation in response to stress	5.594829e-5
GO:0008616	queuosine biosynthetic process	5.594829e-5
GO:0002897	positive regulation of central B cell tolerance induction	5.594829e-5
GO:0002508	central tolerance induction	5.594829e-5
GO:0043173	nucleotide salvage	5.880923e-5
GO:0019348	dolichol metabolic process	5.880923e-5
GO:0009119	ribonucleoside metabolic process	5.892181e-5
GO:0006259	DNA metabolic process	5.974549e-5
GO:0001732	formation of translation initiation complex	6.103996e-5
GO:0030836	positive regulation of actin filament depolymerization	7.960769e-5
GO:0006561	proline biosynthetic process	8.492802e-5
GO:0043101	purine-containing compound salvage	8.521498e-5
GO:0007099	centriole replication	9.673724e-5
GO:0016574	histone ubiquitination	9.741398e-5
GO:0018293	protein-FAD linkage	1.053137e-4
GO:0032782	bile acid secretion	1.053137e-4
GO:0006121	mitochondrial electron transport, succinate to ubiquinone	1.053137e-4
GO:0003096	renal sodium ion transport	1.053137e-4
GO:0006166	purine ribonucleoside salvage	1.105273e-4
GO:0009169	purine ribonucleoside monophosphate catabolic process	1.204505e-4
GO:0019236	response to pheromone	1.259972e-4
GO:0044260	cellular macromolecule metabolic process	1.303322e-4
GO:0060911	cardiac cell fate commitment	1.354308e-4
GO:0097028	dendritic cell differentiation	1.662206e-4
GO:0007191	activation of adenylate cyclase activity by dopamine receptor signaling pathway	1.706973e-4
GO:0071480	cellular response to gamma radiation	1.841305e-4
GO:0017148	negative regulation of translation	1.964503e-4
GO:0030032	lamellipodium assembly	2.099546e-4
GO:0009452	RNA capping	2.325753e-4
GO:0034641	cellular nitrogen compound metabolic process	2.505974e-4
GO:0006408	snRNA export from nucleus	2.683727e-4
GO:0032836	glomerular basement membrane development	2.735985e-4
GO:0016070	RNA metabolic process	2.779477e-4
GO:0006420	arginyl-tRNA aminoacylation	2.794449e-4
GO:0044314	protein K27-linked ubiquitination	2.810105e-4
GO:0042851	L-alanine metabolic process	2.810105e-4
GO:0016601	Rac protein signal transduction	2.834509e-4
GO:0051712	positive regulation of killing of cells of other organism	2.891149e-4
GO:0061084	negative regulation of protein refolding	3.051710e-4
GO:0006407	rRNA export from nucleus	3.051710e-4
GO:0051176	positive regulation of sulfur metabolic process	3.053190e-4
GO:0006476	protein deacetylation	3.429783e-4
GO:0060923	cardiac muscle cell fate commitment	3.458036e-4
GO:0034393	positive regulation of smooth muscle cell apoptosis	3.490198e-4
GO:0046112	nucleobase biosynthetic process	3.553715e-4
GO:0045885	positive regulation of survival gene product expression	3.587808e-4
GO:0051029	rRNA transport	3.614927e-4
GO:0035601	protein deacylation	3.640045e-4
GO:0035519	protein K29-linked ubiquitination	3.890369e-4
GO:0050775	positive regulation of dendrite morphogenesis	4.124281e-4
GO:0045040	protein import into mitochondrial outer membrane	4.257554e-4
GO:0006297	nucleotide-excision repair, DNA gap filling	4.441456e-4
GO:0072302	negative regulation of metanephric glomerular mesangial cell proliferation	4.496572e-4
GO:2001076	positive regulation of metanephric ureteric bud development	4.496572e-4
GO:0010960	magnesium ion homeostasis	4.496572e-4
GO:0007356	thorax and anterior abdomen determination	4.496572e-4
GO:0070318	positive regulation of G0 to G1 transition	4.624874e-4
GO:0046984	regulation of hemoglobin biosynthetic process	4.624874e-4
GO:0031547	brain-derived neurotrophic factor receptor signaling pathway	4.624874e-4
GO:0045626	negative regulation of T-helper 1 cell differentiation	5.162013e-4
GO:0031081	nuclear pore distribution	5.162013e-4
GO:0000238	zygotene	5.162013e-4
GO:0034137	positive regulation of toll-like receptor 2 signaling pathway	6.133870e-4
GO:2000781	positive regulation of double-strand break repair	6.133870e-4
GO:0006021	inositol biosynthetic process	6.133870e-4
GO:0006427	histidyl-tRNA aminoacylation	6.133870e-4
GO:0010155	regulation of proton transport	6.197484e-4
GO:0008634	negative regulation of survival gene product expression	6.402572e-4
GO:0070914	UV-damage excision repair	6.513385e-4
GO:0002635	negative regulation of germinal center formation	6.513385e-4
GO:0072054	renal outer medulla development	6.639052e-4
GO:0043415	positive regulation of skeletal muscle tissue regeneration	6.815590e-4
GO:0007060	male meiosis chromosome segregation	6.815590e-4
GO:0051586	positive regulation of dopamine uptake	6.965623e-4
GO:0046881	positive regulation of follicle-stimulating hormone secretion	6.965623e-4
GO:0072006	nephron development	7.396888e-4
GO:0014812	muscle cell migration	7.509743e-4
GO:0006418	tRNA aminoacylation for protein translation	7.710137e-4
GO:0070584	mitochondrion morphogenesis	8.105443e-4
GO:0031274	positive regulation of pseudopodium assembly	8.151509e-4
GO:0032088	negative regulation of NF-kappaB transcription factor activity	8.165398e-4
GO:0009948	anterior/posterior axis specification	8.339551e-4
GO:0006310	DNA recombination	8.417478e-4
GO:0045947	negative regulation of translational initiation	8.439229e-4
GO:0060359	response to ammonium ion	8.785385e-4
GO:0072369	regulation of lipid transport by positive regulation of transcription from RNA polymerase II promoter	8.817838e-4
GO:0072363	regulation of glycolysis by positive regulation of transcription from RNA polymerase II promoter	8.817838e-4
GO:0072366	regulation of cellular ketone metabolic process by positive regulation of transcription from RNA polymerase II promoter	8.817838e-4
GO:0008208	C21-steroid hormone catabolic process	9.167745e-4
GO:0046103	inosine biosynthetic process	9.167745e-4
GO:0006154	adenosine catabolic process	9.167745e-4
GO:0008652	cellular amino acid biosynthetic process	9.198512e-4
GO:0072053	renal inner medulla development	9.515773e-4
GO:0060011	Sertoli cell proliferation	9.515773e-4
GO:0043555	regulation of translation in response to stress	9.515773e-4
GO:0006807	nitrogen compound metabolic process	9.585360e-4
GO:0007049	cell cycle	9.768077e-4
GO:0045792	negative regulation of cell size	9.953348e-4
GO:0032415	regulation of sodium:hydrogen antiporter activity	1.037735e-3
GO:0035520	monoubiquitinated protein deubiquitination	1.039433e-3
GO:0010661	positive regulation of muscle cell apoptosis	1.064505e-3
GO:0046434	organophosphate catabolic process	1.193635e-3
GO:0060214	endocardium formation	1.218067e-3
GO:0044088	regulation of vacuole organization	1.223951e-3
GO:0035621	ER to Golgi ceramide transport	1.223951e-3
GO:0033962	cytoplasmic mRNA processing body assembly	1.253203e-3
GO:0016142	O-glycoside catabolic process	1.268187e-3
GO:0055062	phosphate ion homeostasis	1.296425e-3
GO:0009744	response to sucrose stimulus	1.338312e-3
GO:0051451	myoblast migration	1.376042e-3
GO:0060439	trachea morphogenesis	1.423677e-3
GO:0045686	negative regulation of glial cell differentiation	1.436729e-3
GO:0033182	regulation of histone ubiquitination	1.460176e-3
GO:0006258	UDP-glucose catabolic process	1.460176e-3
GO:0010725	regulation of primitive erythrocyte differentiation	1.460176e-3
GO:0033627	cell adhesion mediated by integrin	1.470673e-3
GO:0014047	glutamate secretion	1.470673e-3
GO:0031272	regulation of pseudopodium assembly	1.470673e-3
GO:0051131	chaperone-mediated protein complex assembly	1.483872e-3
GO:0032930	positive regulation of superoxide anion generation	1.483872e-3
GO:0070534	protein K63-linked ubiquitination	1.494650e-3
GO:2000277	positive regulation of oxidative phosphorylation uncoupler activity	1.518460e-3
GO:0032981	mitochondrial respiratory chain complex I assembly	1.590440e-3
GO:0033615	mitochondrial proton-transporting ATP synthase complex assembly	1.592151e-3
GO:0008617	guanosine metabolic process	1.592151e-3
GO:0051182	coenzyme transport	1.626555e-3
GO:0060434	bronchus morphogenesis	1.626555e-3
GO:0006383	transcription from RNA polymerase III promoter	1.626555e-3
GO:0007067	mitosis	1.769469e-3
GO:0048285	organelle fission	1.853873e-3
GO:0070316	regulation of G0 to G1 transition	1.893762e-3
GO:0007212	dopamine receptor signaling pathway	1.894275e-3
GO:0022402	cell cycle process	1.981564e-3
GO:0000087	M phase of mitotic cell cycle	2.011344e-3
GO:0010390	histone monoubiquitination	2.026535e-3
GO:0015872	dopamine transport	2.050507e-3
GO:0010453	regulation of cell fate commitment	2.054893e-3
GO:0042026	protein refolding	2.062832e-3
GO:0006213	pyrimidine nucleoside metabolic process	2.067682e-3
GO:0006883	cellular sodium ion homeostasis	2.152044e-3
GO:2000043	regulation of cardiac cell fate specification	2.156742e-3
GO:0042986	positive regulation of amyloid precursor protein biosynthetic process	2.156742e-3
GO:0034619	cellular chaperone-mediated protein complex assembly	2.156742e-3
GO:0001963	synaptic transmission, dopaminergic	2.172852e-3
GO:0046587	positive regulation of calcium-dependent cell-cell adhesion	2.179529e-3
GO:0071279	cellular response to cobalt ion	2.182099e-3
GO:0035522	monoubiquitinated histone H2A deubiquitination	2.182099e-3
GO:0072334	UDP-galactose transmembrane transport	2.182099e-3
GO:0032802	low-density lipoprotein particle receptor catabolic process	2.182099e-3
GO:0010637	negative regulation of mitochondrial fusion	2.182099e-3
GO:0032835	glomerulus development	2.183651e-3
GO:0060492	lung induction	2.353814e-3
GO:0060452	positive regulation of cardiac muscle contraction	2.353814e-3
GO:0061290	canonical Wnt receptor signaling pathway involved in metanephric kidney development	2.399739e-3
GO:0051030	snRNA transport	2.411869e-3
GO:0046853	inositol or phosphatidylinositol phosphorylation	2.411869e-3
GO:0000492	box C/D snoRNP assembly	2.411869e-3
GO:0046102	inosine metabolic process	2.411869e-3
GO:0034227	tRNA thio-modification	2.557794e-3
GO:0060433	bronchus development	2.581704e-3
GO:0042178	xenobiotic catabolic process	2.671193e-3
GO:0030517	negative regulation of axon extension	2.672018e-3
GO:0051588	regulation of neurotransmitter transport	2.682321e-3
GO:0034645	cellular macromolecule biosynthetic process	2.701889e-3
GO:0072107	positive regulation of ureteric bud formation	2.802746e-3
GO:0002098	tRNA wobble uridine modification	2.818816e-3
GO:0070885	negative regulation of calcineurin-NFAT signaling pathway	2.934133e-3
GO:0014057	positive regulation of acetylcholine secretion	2.934133e-3
GO:0016567	protein ubiquitination	2.957492e-3
GO:0060375	regulation of mast cell differentiation	2.959729e-3
GO:0048840	otolith development	2.959729e-3
GO:0030917	midbrain-hindbrain boundary development	2.967876e-3
GO:0033085	negative regulation of T cell differentiation in thymus	2.973113e-3
GO:0010894	negative regulation of steroid biosynthetic process	2.974239e-3
GO:0072050	S-shaped body morphogenesis	2.984284e-3
GO:0072049	comma-shaped body morphogenesis	2.984284e-3
GO:0006599	phosphagen metabolic process	2.984284e-3
GO:0000226	microtubule cytoskeleton organization	3.035610e-3
GO:0042733	embryonic digit morphogenesis	3.071102e-3
GO:0007405	neuroblast proliferation	3.096263e-3
GO:0008595	anterior/posterior axis specification, embryo	3.189749e-3
GO:0007131	reciprocal meiotic recombination	3.245104e-3
GO:0001842	neural fold formation	3.253233e-3
GO:0043094	cellular metabolic compound salvage	3.283231e-3
GO:0006144	purine base metabolic process	3.295860e-3
GO:0010804	negative regulation of tumor necrosis factor-mediated signaling pathway	3.373662e-3
GO:0072428	signal transduction involved in intra-S DNA damage checkpoint	3.411752e-3
GO:0051865	protein autoubiquitination	3.457770e-3
GO:0046676	negative regulation of insulin secretion	3.467541e-3
GO:0060739	mesenchymal-epithelial cell signaling involved in prostate gland development	3.605239e-3
GO:0006429	leucyl-tRNA aminoacylation	3.605239e-3
GO:0044340	canonical Wnt receptor signaling pathway involved in regulation of cell proliferation	3.635145e-3
GO:0006560	proline metabolic process	3.635145e-3
GO:0046985	positive regulation of hemoglobin biosynthetic process	3.644240e-3
GO:0000972	transcription-dependent tethering of RNA polymerase II gene DNA at nuclear periphery	3.644240e-3
GO:0043973	histone H3-K4 acetylation	3.644240e-3
GO:0006601	creatine biosynthetic process	3.644240e-3
GO:0001788	antibody-dependent cellular cytotoxicity	3.644240e-3
GO:0019376	galactolipid catabolic process	3.657551e-3
GO:0021903	rostrocaudal neural tube patterning	3.727928e-3
GO:0048639	positive regulation of developmental growth	3.735197e-3
GO:0000462	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)	3.736026e-3
GO:0051387	negative regulation of nerve growth factor receptor signaling pathway	3.782344e-3
GO:0031581	hemidesmosome assembly	3.923033e-3
GO:0060047	heart contraction	3.939202e-3
GO:0050849	negative regulation of calcium-mediated signaling	4.037864e-3
GO:0030516	regulation of axon extension	4.070816e-3
GO:0050768	negative regulation of neurogenesis	4.313137e-3
GO:0051298	centrosome duplication	4.422314e-3
GO:0060033	anatomical structure regression	4.452445e-3
GO:0022403	cell cycle phase	4.455921e-3
GO:0045625	regulation of T-helper 1 cell differentiation	4.467662e-3
GO:0000184	nuclear-transcribed mRNA catabolic process, nonsense-mediated decay	4.492768e-3
GO:0002645	positive regulation of tolerance induction	4.520662e-3
GO:0042559	pteridine-containing compound biosynthetic process	4.522388e-3
GO:0006513	protein monoubiquitination	4.570359e-3
GO:0072367	regulation of lipid transport by regulation of transcription from RNA polymerase II promoter	4.596355e-3
GO:0072361	regulation of glycolysis by regulation of transcription from RNA polymerase II promoter	4.596355e-3
GO:2000649	regulation of sodium ion transmembrane transporter activity	4.667951e-3
GO:0043628	ncRNA 3'-end processing	4.667951e-3
GO:0015886	heme transport	4.705071e-3
GO:0060523	prostate epithelial cord elongation	4.784056e-3
GO:0007098	centrosome cycle	4.907254e-3
GO:0046716	muscle cell homeostasis	5.151782e-3
GO:0007051	spindle organization	5.207097e-3
GO:0070194	synaptonemal complex disassembly	5.243198e-3
GO:0040040	thermosensory behavior	5.243198e-3
GO:0043309	regulation of eosinophil degranulation	5.243198e-3
GO:0007625	grooming behavior	5.248599e-3
GO:0061324	canonical Wnt receptor signaling pathway involved in positive regulation of cardiac outflow tract cell proliferation	5.368776e-3
GO:0048386	positive regulation of retinoic acid receptor signaling pathway	5.368776e-3
GO:0014909	smooth muscle cell migration	5.368776e-3
GO:0022617	extracellular matrix disassembly	5.374266e-3
GO:0043687	post-translational protein modification	5.457958e-3
GO:0030031	cell projection assembly	5.467529e-3
GO:0006290	pyrimidine dimer repair	5.612039e-3
GO:0060807	regulation of transcription from RNA polymerase II promoter involved in definitive endodermal cell fate specification	5.621587e-3
GO:0016191	synaptic vesicle uncoating	5.621587e-3
GO:0003142	cardiogenic plate morphogenesis	5.621587e-3
GO:0001828	inner cell mass cellular morphogenesis	5.621587e-3
GO:0033523	histone H2B ubiquitination	5.647432e-3
GO:0021575	hindbrain morphogenesis	5.684021e-3
GO:0090196	regulation of chemokine secretion	5.776450e-3
GO:0016554	cytidine to uridine editing	5.828503e-3
GO:0072301	regulation of metanephric glomerular mesangial cell proliferation	5.828503e-3
GO:0042417	dopamine metabolic process	5.876967e-3
GO:0034505	tooth mineralization	5.934982e-3
GO:0060535	trachea cartilage morphogenesis	6.059094e-3
GO:0034329	cell junction assembly	6.159642e-3
GO:0043046	DNA methylation involved in gamete generation	6.161436e-3
GO:0090263	positive regulation of canonical Wnt receptor signaling pathway	6.212653e-3
GO:0007044	cell-substrate junction assembly	6.226047e-3
GO:0002921	negative regulation of humoral immune response	6.261851e-3
GO:0060737	prostate gland morphogenetic growth	6.261851e-3
GO:0002438	acute inflammatory response to antigenic stimulus	6.261851e-3
GO:0072210	metanephric nephron development	6.359049e-3
GO:0051292	nuclear pore complex assembly	6.404597e-3
GO:0032092	positive regulation of protein binding	6.439945e-3
GO:0008033	tRNA processing	6.454278e-3
GO:0060081	membrane hyperpolarization	6.512958e-3
GO:0060972	left/right pattern formation	6.649088e-3
GO:0090278	negative regulation of peptide hormone secretion	6.737829e-3
GO:0045773	positive regulation of axon extension	6.804865e-3
GO:0030011	maintenance of cell polarity	6.885944e-3
GO:0014002	astrocyte development	6.951671e-3
GO:0002021	response to dietary excess	6.951671e-3
GO:0006603	phosphocreatine metabolic process	7.014835e-3
GO:0002651	positive regulation of tolerance induction to self antigen	7.014835e-3
GO:0009059	macromolecule biosynthetic process	7.073443e-3
GO:2000507	positive regulation of energy homeostasis	7.083564e-3
GO:2000253	positive regulation of feeding behavior	7.083564e-3
GO:0051668	localization within membrane	7.137199e-3
GO:0019047	provirus integration	7.142905e-3
GO:0030328	prenylcysteine catabolic process	7.142905e-3
GO:0016140	O-glycoside metabolic process	7.142905e-3
GO:0006431	methionyl-tRNA aminoacylation	7.142905e-3
GO:0001811	negative regulation of type I hypersensitivity	7.142905e-3
GO:0002638	negative regulation of immunoglobulin production	7.142905e-3
GO:0071545	inositol phosphate catabolic process	7.147587e-3
GO:0032099	negative regulation of appetite	7.147587e-3
GO:0032446	protein modification by small protein conjugation	7.330239e-3
GO:0000105	histidine biosynthetic process	7.465833e-3
GO:0031047	gene silencing by RNA	7.558566e-3
GO:0072274	metanephric glomerular basement membrane development	7.879402e-3
GO:0080164	regulation of nitric oxide metabolic process	7.879402e-3
GO:0072249	metanephric glomerular visceral epithelial cell development	7.879402e-3
GO:0060262	negative regulation of N-terminal protein palmitoylation	7.879402e-3
GO:0022615	protein to membrane docking	7.879402e-3
GO:0048677	axon extension involved in regeneration	7.879402e-3
GO:0003026	regulation of systemic arterial blood pressure by aortic arch baroreceptor feedback	7.879402e-3
GO:0046498	S-adenosylhomocysteine metabolic process	7.895550e-3
GO:0006809	nitric oxide biosynthetic process	7.895550e-3
GO:0006563	L-serine metabolic process	7.895550e-3
GO:0030261	chromosome condensation	8.132342e-3
GO:0050658	RNA transport	8.149287e-3
GO:0032535	regulation of cellular component size	8.164971e-3
GO:0032096	negative regulation of response to food	8.285690e-3
GO:0006777	Mo-molybdopterin cofactor biosynthetic process	8.285690e-3
GO:0060649	mammary gland bud elongation	8.351392e-3
GO:0060659	nipple sheath formation	8.351392e-3
GO:2000778	positive regulation of interleukin-6 secretion	8.351392e-3
GO:0050668	positive regulation of homocysteine metabolic process	8.351392e-3
GO:0006428	isoleucyl-tRNA aminoacylation	8.351392e-3
GO:0045963	negative regulation of dopamine metabolic process	8.351392e-3
GO:2000505	regulation of energy homeostasis	8.435999e-3
GO:0002524	hypersensitivity	8.435999e-3
GO:0009164	nucleoside catabolic process	8.507646e-3
GO:0007076	mitotic chromosome condensation	8.507646e-3
GO:2000466	negative regulation of glycogen (starch) synthase activity	8.530873e-3
GO:0031125	rRNA 3'-end processing	8.530873e-3
GO:0000053	argininosuccinate metabolic process	8.592571e-3
GO:0048178	negative regulation of hepatocyte growth factor biosynthetic process	8.592571e-3
GO:0071539	protein localization to centrosome	8.592571e-3
GO:0010878	cholesterol storage	8.592571e-3
GO:2000275	regulation of oxidative phosphorylation uncoupler activity	9.020503e-3
GO:0046032	ADP catabolic process	9.020503e-3
GO:0046709	IDP catabolic process	9.020503e-3
GO:0070120	ciliary neurotrophic factor-mediated signaling pathway	9.058715e-3
GO:0001895	retina homeostasis	9.104239e-3
GO:0044339	canonical Wnt receptor signaling pathway involved in osteoblast differentiation	9.114505e-3
GO:0046931	pore complex assembly	9.114505e-3
GO:0044338	canonical Wnt receptor signaling pathway involved in mesenchymal stem cell differentiation	9.114505e-3
GO:0007008	outer mitochondrial membrane organization	9.270130e-3
GO:0010721	negative regulation of cell development	9.281535e-3
GO:0006260	DNA replication	9.594940e-3
GO:0060215	primitive hemopoiesis	9.645436e-3
GO:0021869	forebrain ventricular zone progenitor cell division	9.645436e-3
GO:0055075	potassium ion homeostasis	9.764487e-3
GO:0043124	negative regulation of I-kappaB kinase/NF-kappaB cascade	9.825347e-3
GO:0045927	positive regulation of growth	1.016052e-2
GO:0032349	positive regulation of aldosterone biosynthetic process	1.021846e-2
GO:0060539	diaphragm development	1.027267e-2
GO:0014056	regulation of acetylcholine secretion	1.038625e-2
GO:0051261	protein depolymerization	1.038625e-2
GO:0009082	branched chain family amino acid biosynthetic process	1.038625e-2
GO:0000578	embryonic axis specification	1.063664e-2
GO:0032456	endocytic recycling	1.065325e-2
GO:0045764	positive regulation of cellular amino acid metabolic process	1.072138e-2
GO:0035404	histone-serine phosphorylation	1.072138e-2
GO:0044062	regulation of excretion	1.073393e-2
GO:0001759	organ induction	1.085662e-2
GO:0045116	protein neddylation	1.092333e-2
GO:0071777	positive regulation of cell cycle cytokinesis	1.099531e-2
GO:0090234	regulation of kinetochore assembly	1.114343e-2
GO:0090169	regulation of spindle assembly	1.114343e-2
GO:0060166	olfactory pit development	1.114343e-2
GO:0072073	kidney epithelium development	1.122995e-2
GO:0032703	negative regulation of interleukin-2 production	1.132894e-2
GO:0042053	regulation of dopamine metabolic process	1.137694e-2
GO:0021895	cerebral cortex neuron differentiation	1.137773e-2
GO:0072166	posterior mesonephric tubule development	1.143109e-2
GO:0043461	proton-transporting ATP synthase complex assembly	1.143109e-2
GO:0032727	positive regulation of interferon-alpha production	1.143109e-2
GO:0035802	adrenal cortex formation	1.143109e-2
GO:0051349	positive regulation of lyase activity	1.144204e-2
GO:0003065	positive regulation of heart rate by epinephrine	1.158282e-2
GO:0060484	lung-associated mesenchyme development	1.163721e-2
GO:0042069	regulation of catecholamine metabolic process	1.165872e-2
GO:0001958	endochondral ossification	1.170093e-2
GO:0051257	spindle midzone assembly involved in meiosis	1.191511e-2
GO:0001975	response to amphetamine	1.230506e-2
GO:0060440	trachea formation	1.255437e-2
GO:0035810	positive regulation of urine volume	1.255437e-2
GO:0051590	positive regulation of neurotransmitter transport	1.255437e-2
GO:0031929	TOR signaling cascade	1.259030e-2
GO:0045604	regulation of epidermal cell differentiation	1.277453e-2
GO:0045751	negative regulation of Toll signaling pathway	1.282563e-2
GO:0060064	Spemann organizer formation at the anterior end of the primitive streak	1.282563e-2
GO:2000256	positive regulation of male germ cell proliferation	1.282563e-2
GO:0044090	positive regulation of vacuole organization	1.282563e-2
GO:0015739	sialic acid transport	1.282563e-2
GO:0019428	allantoin biosynthetic process	1.282563e-2
GO:0033314	mitotic cell cycle DNA replication checkpoint	1.282563e-2
GO:0042231	interleukin-13 biosynthetic process	1.282563e-2
GO:0007016	cytoskeletal anchoring at plasma membrane	1.294271e-2
GO:0030889	negative regulation of B cell proliferation	1.295446e-2
GO:0032481	positive regulation of type I interferon production	1.300649e-2
GO:0002053	positive regulation of mesenchymal cell proliferation	1.304265e-2
GO:0019751	polyol metabolic process	1.307980e-2
GO:0060981	cell migration involved in coronary angiogenesis	1.317331e-2
GO:0070884	regulation of calcineurin-NFAT signaling pathway	1.317331e-2
GO:0044334	canonical Wnt receptor signaling pathway involved in positive regulation of epithelial to mesenchymal transition	1.317331e-2
GO:0071670	smooth muscle cell chemotaxis	1.317331e-2
GO:0032602	chemokine production	1.317331e-2
GO:0000073	spindle pole body separation	1.317331e-2
GO:0010747	positive regulation of plasma membrane long-chain fatty acid transport	1.317331e-2
GO:0006713	glucocorticoid catabolic process	1.317331e-2
GO:0010909	positive regulation of heparan sulfate proteoglycan biosynthetic process	1.317331e-2
GO:0051138	positive regulation of NK T cell differentiation	1.318918e-2
GO:0002741	positive regulation of cytokine secretion involved in immune response	1.321696e-2
GO:0002268	follicular dendritic cell differentiation	1.321696e-2
GO:0032107	regulation of response to nutrient levels	1.325628e-2
GO:0002825	regulation of T-helper 1 type immune response	1.325628e-2
GO:0060707	trophoblast giant cell differentiation	1.334478e-2
GO:0034141	positive regulation of toll-like receptor 3 signaling pathway	1.364086e-2
GO:0048026	positive regulation of nuclear mRNA splicing, via spliceosome	1.365234e-2
GO:0008366	axon ensheathment	1.380497e-2
GO:0030033	microvillus assembly	1.387410e-2
GO:0060158	activation of phospholipase C activity by dopamine receptor signaling pathway	1.387410e-2
GO:0046323	glucose import	1.387410e-2
GO:0009826	unidimensional cell growth	1.387410e-2
GO:0006388	tRNA splicing, via endonucleolytic cleavage and ligation	1.387410e-2
GO:0043170	macromolecule metabolic process	1.415190e-2
GO:0032055	negative regulation of translation in response to stress	1.429201e-2
GO:0072061	inner medullary collecting duct development	1.430146e-2
GO:0072060	outer medullary collecting duct development	1.430146e-2
GO:0071603	endothelial cell-cell adhesion	1.430146e-2
GO:0016332	establishment or maintenance of polarity of embryonic epithelium	1.430146e-2
GO:0007190	activation of adenylate cyclase activity	1.457659e-2