Novel motif:97

name:	motif97_TTCCCT

Association to promoter expression in human samples<b>Summary:</b>Significance of the correlation with CAGE expression, human <br><b>Analyst:</b> Michiel de Hoon<br><br>link to source dataset <br>data

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Association to promoter expression in mouse samples <b>Summary:</b>Significance of the correlation with CAGE expression, mouse <br><b>Analyst:</b> Michiel de Hoon<br><br>link to source dataset <br>data

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GREAT analysis results for human <b>Summary:</b>Genomic Enrichment of Annotations Tool (GREAT, Nat Biotechnol. 2010 May;28(5):495-501) is used to identify, both in human and in mouse, the gene ontology terms of biological processes enriched given the predicted TFBSs, and evaluated the overlap in the top-500 gene ontology terms between human and mouse. For each novel motif, the P value for the overlap was then evaluated by calculating its relative rank with respect to this background distribution.<br>Analyst: Michiel de Hoon<br><br>link to source dataset <br>data

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GO ID	GO Term	p-value
GO:0023052	signaling	7.392064e-18
GO:0051716	cellular response to stimulus	1.612211e-17
GO:0007165	signal transduction	3.068920e-17
GO:0007154	cell communication	1.136325e-16
GO:0050896	response to stimulus	5.028105e-16
GO:0002376	immune system process	1.183045e-13
GO:0006955	immune response	2.753134e-10
GO:0009612	response to mechanical stimulus	7.985176e-10
GO:0060351	cartilage development involved in endochondral bone morphogenesis	1.271766e-9
GO:0010243	response to organic nitrogen	8.902804e-9
GO:0060346	bone trabecula formation	1.083353e-8
GO:0048705	skeletal system morphogenesis	1.267384e-8
GO:0010717	regulation of epithelial to mesenchymal transition	2.164905e-8
GO:0000117	regulation of transcription involved in G2/M-phase of mitotic cell cycle	2.656343e-8
GO:0045619	regulation of lymphocyte differentiation	2.743222e-8
GO:0009617	response to bacterium	3.260517e-8
GO:0046320	regulation of fatty acid oxidation	4.929153e-8
GO:0070887	cellular response to chemical stimulus	5.637673e-8
GO:0010770	positive regulation of cell morphogenesis involved in differentiation	5.705915e-8
GO:0061084	negative regulation of protein refolding	5.856705e-8
GO:0015695	organic cation transport	6.198288e-8
GO:0045580	regulation of T cell differentiation	6.307863e-8
GO:2000171	negative regulation of dendrite development	1.087680e-7
GO:0046321	positive regulation of fatty acid oxidation	1.128492e-7
GO:0051971	positive regulation of transmission of nerve impulse	1.165811e-7
GO:0060349	bone morphogenesis	1.839424e-7
GO:0010033	response to organic substance	1.902437e-7
GO:0048518	positive regulation of biological process	1.953029e-7
GO:0001957	intramembranous ossification	2.060936e-7
GO:0048706	embryonic skeletal system development	2.077447e-7
GO:0006952	defense response	2.156395e-7
GO:0003337	mesenchymal to epithelial transition involved in metanephros morphogenesis	2.231350e-7
GO:0070372	regulation of ERK1 and ERK2 cascade	2.282276e-7
GO:0061383	trabecula morphogenesis	2.427985e-7
GO:0016477	cell migration	3.239215e-7
GO:0051249	regulation of lymphocyte activation	3.905989e-7
GO:0048522	positive regulation of cellular process	4.072126e-7
GO:0030225	macrophage differentiation	4.393322e-7
GO:0050863	regulation of T cell activation	4.726845e-7
GO:0043149	stress fiber assembly	4.867630e-7
GO:0031646	positive regulation of neurological system process	5.170344e-7
GO:0043200	response to amino acid stimulus	5.892461e-7
GO:0031331	positive regulation of cellular catabolic process	6.015000e-7
GO:0050806	positive regulation of synaptic transmission	6.282940e-7
GO:0060343	trabecula formation	6.766303e-7
GO:0022612	gland morphogenesis	7.320730e-7
GO:0060348	bone development	7.486735e-7
GO:0051094	positive regulation of developmental process	7.994026e-7
GO:0001503	ossification	8.305520e-7
GO:0060350	endochondral bone morphogenesis	9.739134e-7
GO:0050870	positive regulation of T cell activation	1.000867e-6
GO:0046677	response to antibiotic	1.251118e-6
GO:0090190	positive regulation of branching involved in ureteric bud morphogenesis	1.531067e-6
GO:0072283	metanephric renal vesicle morphogenesis	1.588853e-6
GO:0033135	regulation of peptidyl-serine phosphorylation	1.640175e-6
GO:0010628	positive regulation of gene expression	1.683210e-6
GO:0045621	positive regulation of lymphocyte differentiation	1.788249e-6
GO:0051251	positive regulation of lymphocyte activation	1.814074e-6
GO:0060389	pathway-restricted SMAD protein phosphorylation	1.893928e-6
GO:0002009	morphogenesis of an epithelium	1.901356e-6
GO:0042307	positive regulation of protein import into nucleus	2.155242e-6
GO:0010647	positive regulation of cell communication	2.236241e-6
GO:0045597	positive regulation of cell differentiation	2.240343e-6
GO:0006182	cGMP biosynthetic process	2.257655e-6
GO:0090189	regulation of branching involved in ureteric bud morphogenesis	2.621353e-6
GO:0001754	eye photoreceptor cell differentiation	2.763426e-6
GO:0009893	positive regulation of metabolic process	2.803179e-6
GO:0060740	prostate gland epithelium morphogenesis	2.867282e-6
GO:0033025	regulation of mast cell apoptosis	3.172592e-6
GO:0034764	positive regulation of transmembrane transport	3.373032e-6
GO:0023056	positive regulation of signaling	3.813556e-6
GO:0048732	gland development	3.945698e-6
GO:0010880	regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum	3.981614e-6
GO:0042346	positive regulation of NF-kappaB import into nucleus	4.057268e-6
GO:0032496	response to lipopolysaccharide	4.276377e-6
GO:0048870	cell motility	4.326053e-6
GO:0051091	positive regulation of sequence-specific DNA binding transcription factor activity	4.425801e-6
GO:2000612	regulation of thyroid-stimulating hormone secretion	4.541603e-6
GO:0060512	prostate gland morphogenesis	4.745316e-6
GO:0071363	cellular response to growth factor stimulus	4.751080e-6
GO:0045582	positive regulation of T cell differentiation	4.783093e-6
GO:0010604	positive regulation of macromolecule metabolic process	4.832012e-6
GO:0046638	positive regulation of alpha-beta T cell differentiation	4.877091e-6
GO:0007166	cell surface receptor linked signaling pathway	4.893086e-6
GO:0070848	response to growth factor stimulus	5.181566e-6
GO:0006959	humoral immune response	5.371567e-6
GO:0014075	response to amine stimulus	5.451546e-6
GO:0014003	oligodendrocyte development	6.140381e-6
GO:0033273	response to vitamin	6.268589e-6
GO:0061077	chaperone-mediated protein folding	6.765593e-6
GO:0071310	cellular response to organic substance	7.162569e-6
GO:0031325	positive regulation of cellular metabolic process	7.193361e-6
GO:0045630	positive regulation of T-helper 2 cell differentiation	7.242978e-6
GO:0090316	positive regulation of intracellular protein transport	7.306346e-6
GO:0072077	renal vesicle morphogenesis	7.516001e-6
GO:0046824	positive regulation of nucleocytoplasmic transport	7.733595e-6
GO:0046530	photoreceptor cell differentiation	7.855405e-6
GO:0034123	positive regulation of toll-like receptor signaling pathway	8.008342e-6
GO:0051216	cartilage development	8.272564e-6
GO:0002237	response to molecule of bacterial origin	8.278290e-6
GO:0051043	regulation of membrane protein ectodomain proteolysis	8.417058e-6
GO:0051707	response to other organism	9.619862e-6
GO:0034121	regulation of toll-like receptor signaling pathway	9.798442e-6
GO:0010557	positive regulation of macromolecule biosynthetic process	1.021767e-5
GO:0007155	cell adhesion	1.089791e-5
GO:0002573	myeloid leukocyte differentiation	1.092919e-5
GO:0071705	nitrogen compound transport	1.240882e-5
GO:0000184	nuclear-transcribed mRNA catabolic process, nonsense-mediated decay	1.270426e-5
GO:0048013	ephrin receptor signaling pathway	1.280608e-5
GO:0045923	positive regulation of fatty acid metabolic process	1.283909e-5
GO:0051088	PMA-inducible membrane protein ectodomain proteolysis	1.430211e-5
GO:0072087	renal vesicle development	1.468116e-5
GO:0033081	regulation of T cell differentiation in thymus	1.503726e-5
GO:0072108	positive regulation of mesenchymal to epithelial transition involved in metanephros morphogenesis	1.562228e-5
GO:0042345	regulation of NF-kappaB import into nucleus	1.616614e-5
GO:0071495	cellular response to endogenous stimulus	1.649703e-5
GO:0072278	metanephric comma-shaped body morphogenesis	1.789841e-5
GO:0007610	behavior	1.846049e-5
GO:0031329	regulation of cellular catabolic process	1.854353e-5
GO:0070389	chaperone cofactor-dependent protein refolding	2.032549e-5
GO:2000026	regulation of multicellular organismal development	2.079590e-5
GO:0055094	response to lipoprotein stimulus	2.172487e-5
GO:0051045	negative regulation of membrane protein ectodomain proteolysis	2.272668e-5
GO:0072273	metanephric nephron morphogenesis	2.283049e-5
GO:0033138	positive regulation of peptidyl-serine phosphorylation	2.326662e-5
GO:0003339	regulation of mesenchymal to epithelial transition involved in metanephros morphogenesis	2.346655e-5
GO:0008589	regulation of smoothened signaling pathway	2.359122e-5
GO:0009607	response to biotic stimulus	2.439624e-5
GO:0046635	positive regulation of alpha-beta T cell activation	2.481247e-5
GO:0001101	response to acid	2.514786e-5
GO:0060326	cell chemotaxis	2.559018e-5
GO:0032000	positive regulation of fatty acid beta-oxidation	2.579221e-5
GO:0007218	neuropeptide signaling pathway	2.604035e-5
GO:0032463	negative regulation of protein homooligomerization	2.737464e-5
GO:0001501	skeletal system development	2.927889e-5
GO:0045666	positive regulation of neuron differentiation	3.198310e-5
GO:0048523	negative regulation of cellular process	3.224703e-5
GO:0030520	estrogen receptor signaling pathway	3.226682e-5
GO:0048771	tissue remodeling	3.227101e-5
GO:0010718	positive regulation of epithelial to mesenchymal transition	3.280986e-5
GO:0071674	mononuclear cell migration	3.536696e-5
GO:0051092	positive regulation of NF-kappaB transcription factor activity	3.547326e-5
GO:0001562	response to protozoan	3.728786e-5
GO:0051090	regulation of sequence-specific DNA binding transcription factor activity	3.773085e-5
GO:0032501	multicellular organismal process	3.805708e-5
GO:0019217	regulation of fatty acid metabolic process	3.809884e-5
GO:0061138	morphogenesis of a branching epithelium	3.966662e-5
GO:0042306	regulation of protein import into nucleus	4.103357e-5
GO:0045765	regulation of angiogenesis	4.137306e-5
GO:0072040	negative regulation of mesenchymal stem cell apoptosis involved in nephron morphogenesis	4.369101e-5
GO:0046637	regulation of alpha-beta T cell differentiation	4.750574e-5
GO:0001672	regulation of chromatin assembly or disassembly	4.751444e-5
GO:0010629	negative regulation of gene expression	4.756271e-5
GO:0048513	organ development	4.832208e-5
GO:0003338	metanephros morphogenesis	4.910277e-5
GO:0032510	endosome to lysosome transport via multivesicular body sorting pathway	4.954850e-5
GO:2000276	negative regulation of oxidative phosphorylation uncoupler activity	5.151327e-5
GO:0035359	negative regulation of peroxisome proliferator activated receptor signaling pathway	5.151327e-5
GO:0001763	morphogenesis of a branching structure	5.210715e-5
GO:0001659	temperature homeostasis	5.326530e-5
GO:0072221	metanephric distal convoluted tubule development	5.590407e-5
GO:0019915	lipid storage	5.598043e-5
GO:0072307	regulation of metanephric nephron tubule epithelial cell differentiation	5.687585e-5
GO:0051240	positive regulation of multicellular organismal process	5.868313e-5
GO:0045893	positive regulation of transcription, DNA-dependent	5.964037e-5
GO:0051239	regulation of multicellular organismal process	5.981742e-5
GO:0050900	leukocyte migration	6.255242e-5
GO:0031998	regulation of fatty acid beta-oxidation	6.258141e-5
GO:0015816	glycine transport	6.269874e-5
GO:0050935	iridophore differentiation	6.393824e-5
GO:0048937	lateral line nerve glial cell development	6.393824e-5
GO:0072282	metanephric nephron tubule morphogenesis	6.401652e-5
GO:0048511	rhythmic process	6.428736e-5
GO:0002439	chronic inflammatory response to antigenic stimulus	6.450717e-5
GO:0007399	nervous system development	6.559057e-5
GO:0010944	negative regulation of transcription by competitive promoter binding	6.610325e-5
GO:2000611	positive regulation of thyroid hormone generation	6.673958e-5
GO:0030155	regulation of cell adhesion	7.025916e-5
GO:0045079	negative regulation of chemokine biosynthetic process	7.144256e-5
GO:0060442	branching involved in prostate gland morphogenesis	7.146662e-5
GO:0015696	ammonium transport	7.481288e-5
GO:0007264	small GTPase mediated signal transduction	7.528156e-5
GO:0045059	positive thymic T cell selection	7.812112e-5
GO:0051966	regulation of synaptic transmission, glutamatergic	7.864692e-5
GO:0032365	intracellular lipid transport	7.923582e-5
GO:0034097	response to cytokine stimulus	7.992346e-5
GO:0072088	nephron epithelium morphogenesis	8.153344e-5
GO:0010171	body morphogenesis	8.363207e-5
GO:0032963	collagen metabolic process	8.392577e-5
GO:0009187	cyclic nucleotide metabolic process	8.412923e-5
GO:0072289	metanephric nephron tubule formation	8.582591e-5
GO:0046068	cGMP metabolic process	8.708360e-5
GO:0032462	regulation of protein homooligomerization	9.060703e-5
GO:0045934	negative regulation of nucleobase-containing compound metabolic process	9.810480e-5
GO:0030185	nitric oxide transport	1.029482e-4
GO:0009896	positive regulation of catabolic process	1.029752e-4
GO:0010042	response to manganese ion	1.035937e-4
GO:0051172	negative regulation of nitrogen compound metabolic process	1.060134e-4
GO:0001944	vasculature development	1.061478e-4
GO:0032388	positive regulation of intracellular transport	1.071072e-4
GO:0006954	inflammatory response	1.075602e-4
GO:0010508	positive regulation of autophagy	1.086824e-4
GO:0045087	innate immune response	1.089545e-4
GO:0030878	thyroid gland development	1.102796e-4
GO:0070374	positive regulation of ERK1 and ERK2 cascade	1.122557e-4
GO:0014809	regulation of skeletal muscle contraction by regulation of release of sequestered calcium ion	1.136283e-4
GO:0031327	negative regulation of cellular biosynthetic process	1.145963e-4
GO:0002694	regulation of leukocyte activation	1.156040e-4
GO:0034505	tooth mineralization	1.167539e-4
GO:0042221	response to chemical stimulus	1.174337e-4
GO:0051253	negative regulation of RNA metabolic process	1.191938e-4
GO:0045163	clustering of voltage-gated potassium channels	1.196384e-4
GO:0035148	tube formation	1.205617e-4
GO:0032526	response to retinoic acid	1.231317e-4
GO:0009725	response to hormone stimulus	1.267342e-4
GO:0045834	positive regulation of lipid metabolic process	1.302352e-4
GO:0043555	regulation of translation in response to stress	1.342898e-4
GO:0010470	regulation of gastrulation	1.358093e-4
GO:0050996	positive regulation of lipid catabolic process	1.359767e-4
GO:0045892	negative regulation of transcription, DNA-dependent	1.367350e-4
GO:0042990	regulation of transcription factor import into nucleus	1.382296e-4
GO:0040023	establishment of nucleus localization	1.400170e-4
GO:0040011	locomotion	1.411318e-4
GO:0042832	defense response to protozoan	1.479766e-4
GO:0002064	epithelial cell development	1.483804e-4
GO:0060429	epithelium development	1.487020e-4
GO:0015837	amine transport	1.490327e-4
GO:0071359	cellular response to dsRNA	1.506104e-4
GO:0072305	negative regulation of mesenchymal stem cell apoptosis involved in metanephric nephron morphogenesis	1.514351e-4
GO:2000594	positive regulation of metanephric DCT cell differentiation	1.514351e-4
GO:0039003	pronephric field specification	1.514351e-4
GO:0006853	carnitine shuttle	1.527332e-4
GO:0009651	response to salt stress	1.574078e-4
GO:0009190	cyclic nucleotide biosynthetic process	1.625902e-4
GO:0060688	regulation of morphogenesis of a branching structure	1.629023e-4
GO:0002252	immune effector process	1.649420e-4
GO:0021570	rhombomere 4 development	1.697460e-4
GO:0007267	cell-cell signaling	1.723703e-4
GO:0001773	myeloid dendritic cell activation	1.728768e-4
GO:0009719	response to endogenous stimulus	1.734493e-4
GO:0033619	membrane protein proteolysis	1.765303e-4
GO:0060676	ureteric bud formation	1.804306e-4
GO:0050865	regulation of cell activation	1.825073e-4
GO:0033026	negative regulation of mast cell apoptosis	1.835456e-4
GO:0009645	response to low light intensity stimulus	1.846275e-4
GO:0046690	response to tellurium ion	1.846275e-4
GO:0032509	endosome transport via multivesicular body sorting pathway	1.852782e-4
GO:0046822	regulation of nucleocytoplasmic transport	1.877227e-4
GO:2000113	negative regulation of cellular macromolecule biosynthetic process	1.907258e-4
GO:0071637	regulation of monocyte chemotactic protein-1 production	1.936791e-4
GO:0050794	regulation of cellular process	1.944771e-4
GO:0001568	blood vessel development	1.951746e-4
GO:0019216	regulation of lipid metabolic process	2.011626e-4
GO:0050867	positive regulation of cell activation	2.018409e-4
GO:0009890	negative regulation of biosynthetic process	2.052994e-4
GO:0022407	regulation of cell-cell adhesion	2.062725e-4
GO:0050994	regulation of lipid catabolic process	2.113846e-4
GO:0009894	regulation of catabolic process	2.217582e-4
GO:0002673	regulation of acute inflammatory response	2.261738e-4
GO:0010939	regulation of necrotic cell death	2.282680e-4
GO:0010829	negative regulation of glucose transport	2.301400e-4
GO:0030856	regulation of epithelial cell differentiation	2.312207e-4
GO:0045916	negative regulation of complement activation	2.348704e-4
GO:0051056	regulation of small GTPase mediated signal transduction	2.417405e-4
GO:0002696	positive regulation of leukocyte activation	2.422817e-4
GO:0048645	organ formation	2.426051e-4
GO:0006540	glutamate decarboxylation to succinate	2.447600e-4
GO:0015887	pantothenate transmembrane transport	2.456381e-4
GO:0016598	protein arginylation	2.456381e-4
GO:0015878	biotin transport	2.456381e-4
GO:0048731	system development	2.460622e-4
GO:0043009	chordate embryonic development	2.464387e-4
GO:0001838	embryonic epithelial tube formation	2.477141e-4
GO:0002828	regulation of type 2 immune response	2.496856e-4
GO:0014048	regulation of glutamate secretion	2.498135e-4
GO:0048534	hemopoietic or lymphoid organ development	2.498658e-4
GO:0042462	eye photoreceptor cell development	2.549162e-4
GO:0045861	negative regulation of proteolysis	2.565998e-4
GO:0042127	regulation of cell proliferation	2.567195e-4
GO:0001655	urogenital system development	2.621680e-4
GO:0009605	response to external stimulus	2.631459e-4
GO:0048671	negative regulation of collateral sprouting	2.683589e-4
GO:0072234	metanephric nephron tubule development	2.737498e-4
GO:0060405	regulation of penile erection	2.759575e-4
GO:0032543	mitochondrial translation	2.787598e-4
GO:0032270	positive regulation of cellular protein metabolic process	2.794558e-4
GO:0051247	positive regulation of protein metabolic process	2.815566e-4
GO:0030850	prostate gland development	2.830153e-4
GO:0035279	mRNA cleavage involved in gene silencing by miRNA	2.835578e-4
GO:0060315	negative regulation of ryanodine-sensitive calcium-release channel activity	2.884310e-4
GO:0071345	cellular response to cytokine stimulus	2.917517e-4
GO:0034612	response to tumor necrosis factor	2.943751e-4
GO:0009967	positive regulation of signal transduction	2.950476e-4
GO:0040040	thermosensory behavior	2.983146e-4
GO:0010977	negative regulation of neuron projection development	2.989505e-4
GO:0043401	steroid hormone mediated signaling pathway	2.990405e-4
GO:0031960	response to corticosteroid stimulus	3.033179e-4
GO:0060992	response to fungicide	3.044633e-4
GO:0010558	negative regulation of macromolecule biosynthetic process	3.103171e-4
GO:0002520	immune system development	3.131897e-4
GO:0010761	fibroblast migration	3.155632e-4
GO:0006990	positive regulation of transcription from RNA polymerase II promoter involved in unfolded protein response	3.155979e-4
GO:0042993	positive regulation of transcription factor import into nucleus	3.157797e-4
GO:0015804	neutral amino acid transport	3.305048e-4
GO:0019886	antigen processing and presentation of exogenous peptide antigen via MHC class II	3.418900e-4
GO:0001657	ureteric bud development	3.457535e-4
GO:0010941	regulation of cell death	3.571341e-4
GO:0072003	kidney rudiment formation	3.621635e-4
GO:0043518	negative regulation of DNA damage response, signal transduction by p53 class mediator	3.655155e-4
GO:0003180	aortic valve morphogenesis	3.714727e-4
GO:0010871	negative regulation of receptor biosynthetic process	3.804270e-4
GO:0002684	positive regulation of immune system process	3.821675e-4
GO:0050730	regulation of peptidyl-tyrosine phosphorylation	3.848907e-4
GO:0048709	oligodendrocyte differentiation	3.946163e-4
GO:0050731	positive regulation of peptidyl-tyrosine phosphorylation	3.992127e-4
GO:0072170	metanephric tubule development	3.999833e-4
GO:0046836	glycolipid transport	4.006371e-4
GO:0021546	rhombomere development	4.075323e-4
GO:0000122	negative regulation of transcription from RNA polymerase II promoter	4.123059e-4
GO:0048754	branching morphogenesis of a tube	4.231404e-4
GO:0044259	multicellular organismal macromolecule metabolic process	4.252600e-4
GO:0090183	regulation of kidney development	4.324021e-4
GO:0048519	negative regulation of biological process	4.347648e-4
GO:0002437	inflammatory response to antigenic stimulus	4.360644e-4
GO:0043372	positive regulation of CD4-positive, alpha-beta T cell differentiation	4.362704e-4
GO:0009649	entrainment of circadian clock	4.400689e-4
GO:0032332	positive regulation of chondrocyte differentiation	4.466184e-4
GO:0002521	leukocyte differentiation	4.578235e-4
GO:0045672	positive regulation of osteoclast differentiation	4.707922e-4
GO:0015879	carnitine transport	4.720619e-4
GO:0051222	positive regulation of protein transport	4.723659e-4
GO:0014070	response to organic cyclic compound	4.750016e-4
GO:0030097	hemopoiesis	4.772866e-4
GO:0019883	antigen processing and presentation of endogenous antigen	4.798064e-4
GO:0032673	regulation of interleukin-4 production	4.875623e-4
GO:0044130	negative regulation of growth of symbiont in host	4.885249e-4
GO:0070842	aggresome assembly	4.986170e-4
GO:2000275	regulation of oxidative phosphorylation uncoupler activity	5.061908e-4
GO:0060373	regulation of ventricular cardiomyocyte membrane depolarization	5.061908e-4
GO:0009642	response to light intensity	5.129212e-4
GO:0030522	intracellular receptor mediated signaling pathway	5.139361e-4
GO:0050852	T cell receptor signaling pathway	5.193477e-4
GO:0033157	regulation of intracellular protein transport	5.210291e-4
GO:0034114	regulation of heterotypic cell-cell adhesion	5.245020e-4
GO:0070587	regulation of cell-cell adhesion involved in gastrulation	5.245020e-4
GO:0014015	positive regulation of gliogenesis	5.297617e-4
GO:0001958	endochondral ossification	5.361784e-4
GO:0032330	regulation of chondrocyte differentiation	5.386353e-4
GO:0071639	positive regulation of monocyte chemotactic protein-1 production	5.392648e-4
GO:0010715	regulation of extracellular matrix disassembly	5.428767e-4
GO:0032722	positive regulation of chemokine production	5.525353e-4
GO:0060325	face morphogenesis	5.541473e-4
GO:0042220	response to cocaine	5.565134e-4
GO:0043011	myeloid dendritic cell differentiation	5.715638e-4
GO:0045595	regulation of cell differentiation	5.723455e-4
GO:0010565	regulation of cellular ketone metabolic process	5.751908e-4
GO:0034116	positive regulation of heterotypic cell-cell adhesion	5.802488e-4
GO:0071360	cellular response to exogenous dsRNA	5.852147e-4
GO:0050778	positive regulation of immune response	5.909175e-4
GO:0042981	regulation of apoptosis	5.911259e-4
GO:0072148	epithelial cell fate commitment	5.931482e-4
GO:0008284	positive regulation of cell proliferation	5.986467e-4
GO:0072009	nephron epithelium development	5.988655e-4
GO:0006448	regulation of translational elongation	5.989543e-4
GO:0072028	nephron morphogenesis	6.013803e-4
GO:0035239	tube morphogenesis	6.020205e-4
GO:0090051	negative regulation of cell migration involved in sprouting angiogenesis	6.035971e-4
GO:0060056	mammary gland involution	6.143377e-4
GO:0071460	cellular response to cell-matrix adhesion	6.211350e-4
GO:0042461	photoreceptor cell development	6.318198e-4
GO:0007602	phototransduction	6.336168e-4
GO:0060678	dichotomous subdivision of terminal units involved in ureteric bud branching	6.346923e-4
GO:0010883	regulation of lipid storage	6.358996e-4
GO:0045880	positive regulation of smoothened signaling pathway	6.492142e-4
GO:0032880	regulation of protein localization	6.640612e-4
GO:0060316	positive regulation of ryanodine-sensitive calcium-release channel activity	6.696038e-4
GO:0051454	intracellular pH elevation	6.868722e-4
GO:0010771	negative regulation of cell morphogenesis involved in differentiation	6.885371e-4
GO:0060406	positive regulation of penile erection	6.952779e-4
GO:0033089	positive regulation of T cell differentiation in thymus	6.987585e-4
GO:0060559	positive regulation of calcidiol 1-monooxygenase activity	6.994398e-4
GO:0072175	epithelial tube formation	7.055978e-4
GO:0061035	regulation of cartilage development	7.142778e-4
GO:0031223	auditory behavior	7.425047e-4
GO:0048692	negative regulation of axon extension involved in regeneration	7.443886e-4
GO:0007225	patched ligand maturation	7.443886e-4
GO:0071300	cellular response to retinoic acid	7.490576e-4
GO:0009792	embryo development ending in birth or egg hatching	7.498239e-4
GO:0019882	antigen processing and presentation	7.547585e-4
GO:0001869	negative regulation of complement activation, lectin pathway	7.694238e-4
GO:0060562	epithelial tube morphogenesis	7.744015e-4
GO:0021602	cranial nerve morphogenesis	7.819309e-4
GO:0045061	thymic T cell selection	7.899115e-4
GO:0070668	positive regulation of mast cell proliferation	7.949513e-4
GO:0071299	cellular response to vitamin A	7.986649e-4
GO:0006768	biotin metabolic process	8.007493e-4
GO:0051148	negative regulation of muscle cell differentiation	8.100178e-4
GO:0009755	hormone-mediated signaling pathway	8.128197e-4
GO:0006865	amino acid transport	8.134045e-4
GO:0071338	positive regulation of hair follicle cell proliferation	8.508978e-4
GO:0002763	positive regulation of myeloid leukocyte differentiation	8.581180e-4
GO:0046168	glycerol-3-phosphate catabolic process	8.685839e-4
GO:0032964	collagen biosynthetic process	8.688243e-4
GO:0015908	fatty acid transport	8.698557e-4
GO:0031401	positive regulation of protein modification process	8.710151e-4
GO:0045073	regulation of chemokine biosynthetic process	8.775191e-4
GO:0034447	very-low-density lipoprotein particle clearance	8.810852e-4
GO:0035112	genitalia morphogenesis	8.824725e-4
GO:0030518	steroid hormone receptor signaling pathway	8.869024e-4
GO:0001658	branching involved in ureteric bud morphogenesis	8.937857e-4
GO:0016331	morphogenesis of embryonic epithelium	8.973364e-4
GO:0071404	cellular response to low-density lipoprotein particle stimulus	8.993723e-4
GO:0072210	metanephric nephron development	9.011719e-4
GO:0034341	response to interferon-gamma	9.015241e-4
GO:0045647	negative regulation of erythrocyte differentiation	9.020244e-4
GO:0060675	ureteric bud morphogenesis	9.066442e-4
GO:0015697	quaternary ammonium group transport	9.096975e-4
GO:0071276	cellular response to cadmium ion	9.152689e-4
GO:0048536	spleen development	9.225360e-4
GO:0045766	positive regulation of angiogenesis	9.312915e-4
GO:0071481	cellular response to X-ray	9.329798e-4
GO:0032459	regulation of protein oligomerization	9.375419e-4
GO:0007274	neuromuscular synaptic transmission	9.420644e-4
GO:0060323	head morphogenesis	9.433024e-4
GO:0071402	cellular response to lipoprotein particle stimulus	9.554441e-4
GO:0045086	positive regulation of interleukin-2 biosynthetic process	9.632561e-4
GO:0045058	T cell selection	9.762782e-4
GO:0007568	aging	9.771057e-4
GO:0071280	cellular response to copper ion	9.839074e-4
GO:0010605	negative regulation of macromolecule metabolic process	9.876882e-4
GO:0060547	negative regulation of necrotic cell death	1.004806e-3
GO:0001831	trophectodermal cellular morphogenesis	1.004806e-3
GO:0030595	leukocyte chemotaxis	1.005907e-3
GO:0002253	activation of immune response	1.024135e-3
GO:0043067	regulation of programmed cell death	1.027424e-3
GO:2000736	regulation of stem cell differentiation	1.032893e-3
GO:0051254	positive regulation of RNA metabolic process	1.037387e-3
GO:0060516	primary prostatic bud elongation	1.039730e-3
GO:0060284	regulation of cell development	1.044040e-3
GO:0071383	cellular response to steroid hormone stimulus	1.053533e-3
GO:0048856	anatomical structure development	1.068819e-3
GO:0043314	negative regulation of neutrophil degranulation	1.068997e-3
GO:0021545	cranial nerve development	1.069931e-3
GO:0043279	response to alkaloid	1.079451e-3
GO:0032410	negative regulation of transporter activity	1.085337e-3
GO:0051066	dihydrobiopterin metabolic process	1.106881e-3
GO:0032314	regulation of Rac GTPase activity	1.123087e-3
GO:0048704	embryonic skeletal system morphogenesis	1.130098e-3
GO:0009409	response to cold	1.142897e-3
GO:0035767	endothelial cell chemotaxis	1.174906e-3
GO:0051013	microtubule severing	1.187570e-3
GO:0060356	leucine import	1.187570e-3
GO:0001823	mesonephros development	1.192493e-3
GO:0003417	growth plate cartilage development	1.195316e-3
GO:0048729	tissue morphogenesis	1.216214e-3
GO:0032663	regulation of interleukin-2 production	1.222577e-3
GO:0072006	nephron development	1.223735e-3
GO:0072387	flavin adenine dinucleotide metabolic process	1.261873e-3
GO:0009956	radial pattern formation	1.278818e-3
GO:0060662	salivary gland cavitation	1.312707e-3
GO:0045944	positive regulation of transcription from RNA polymerase II promoter	1.328119e-3
GO:0002478	antigen processing and presentation of exogenous peptide antigen	1.336161e-3
GO:0019087	transformation of host cell by virus	1.337050e-3
GO:0001543	ovarian follicle rupture	1.337050e-3
GO:0014050	negative regulation of glutamate secretion	1.337542e-3
GO:0046324	regulation of glucose import	1.341465e-3
GO:0032386	regulation of intracellular transport	1.342675e-3
GO:0006004	fucose metabolic process	1.342896e-3
GO:0010885	regulation of cholesterol storage	1.344297e-3
GO:0043313	regulation of neutrophil degranulation	1.345255e-3
GO:0032438	melanosome organization	1.381186e-3
GO:0043903	regulation of symbiosis, encompassing mutualism through parasitism	1.383302e-3
GO:0003416	endochondral bone growth	1.387527e-3
GO:0042759	long-chain fatty acid biosynthetic process	1.391165e-3
GO:0043312	neutrophil degranulation	1.404525e-3
GO:0019884	antigen processing and presentation of exogenous antigen	1.442848e-3
GO:0032713	negative regulation of interleukin-4 production	1.443229e-3
GO:0015909	long-chain fatty acid transport	1.449751e-3
GO:0072205	metanephric collecting duct development	1.452415e-3
GO:0070145	mitochondrial asparaginyl-tRNA aminoacylation	1.459232e-3
GO:0008616	queuosine biosynthetic process	1.459232e-3
GO:0030949	positive regulation of vascular endothelial growth factor receptor signaling pathway	1.462767e-3
GO:0071503	response to heparin	1.488859e-3
GO:0048545	response to steroid hormone stimulus	1.513054e-3
GO:0021936	regulation of cerebellar granule cell precursor proliferation	1.537870e-3
GO:0071985	multivesicular body sorting pathway	1.537870e-3
GO:0050793	regulation of developmental process	1.539677e-3
GO:0035358	regulation of peroxisome proliferator activated receptor signaling pathway	1.557309e-3
GO:0010501	RNA secondary structure unwinding	1.569124e-3
GO:0065007	biological regulation	1.599678e-3
GO:0030574	collagen catabolic process	1.602806e-3
GO:0006198	cAMP catabolic process	1.610098e-3
GO:0019405	alditol catabolic process	1.622194e-3
GO:0070201	regulation of establishment of protein localization	1.624214e-3
GO:0048753	pigment granule organization	1.627125e-3
GO:0043017	positive regulation of lymphotoxin A biosynthetic process	1.634714e-3
GO:0002921	negative regulation of humoral immune response	1.643156e-3
GO:0009123	nucleoside monophosphate metabolic process	1.648273e-3
GO:0002070	epithelial cell maturation	1.651817e-3
GO:0007501	mesodermal cell fate specification	1.670675e-3

GREAT analysis results for mouseGenomic Enrichment of Annotations Tool (GREAT, Nat Biotechnol. 2010 May;28(5):495-501) is used to identify, both in human and in mouse, the gene ontology terms of biological processes enriched given the predicted TFBSs, and evaluated the overlap in the top-500 gene ontology terms between human and mouse. For each novel motif, the P value for the overlap was then evaluated by calculating its relative rank with respect to this background distribution.<br>Analyst: Michiel de Hoon <br><br>link to source dataset <br>data

---

GO ID	GO Term	p-value
GO:0032879	regulation of localization	8.239462e-10
GO:0030799	regulation of cyclic nucleotide metabolic process	1.511920e-9
GO:0043462	regulation of ATPase activity	2.185541e-9
GO:0003208	cardiac ventricle morphogenesis	2.902785e-9
GO:0030049	muscle filament sliding	3.319892e-9
GO:0007522	visceral muscle development	6.744030e-9
GO:0030802	regulation of cyclic nucleotide biosynthetic process	8.595344e-9
GO:0040013	negative regulation of locomotion	1.267219e-8
GO:0045762	positive regulation of adenylate cyclase activity	2.404671e-8
GO:0045761	regulation of adenylate cyclase activity	2.770990e-8
GO:0003229	ventricular cardiac muscle tissue development	2.794433e-8
GO:0010769	regulation of cell morphogenesis involved in differentiation	2.942115e-8
GO:0071260	cellular response to mechanical stimulus	3.688650e-8
GO:0031281	positive regulation of cyclase activity	5.130152e-8
GO:0051270	regulation of cellular component movement	5.558125e-8
GO:0040012	regulation of locomotion	6.762315e-8
GO:0030539	male genitalia development	6.822976e-8
GO:0048813	dendrite morphogenesis	6.876509e-8
GO:0022603	regulation of anatomical structure morphogenesis	8.801994e-8
GO:0007190	activation of adenylate cyclase activity	9.095934e-8
GO:0055010	ventricular cardiac muscle tissue morphogenesis	1.231387e-7
GO:0045348	positive regulation of MHC class II biosynthetic process	1.233047e-7
GO:0055009	atrial cardiac muscle tissue morphogenesis	1.411200e-7
GO:0032642	regulation of chemokine production	1.667894e-7
GO:0050896	response to stimulus	1.887568e-7
GO:0031279	regulation of cyclase activity	1.983274e-7
GO:0030817	regulation of cAMP biosynthetic process	1.984243e-7
GO:0048806	genitalia development	2.343405e-7
GO:0003206	cardiac chamber morphogenesis	2.583831e-7
GO:0007166	cell surface receptor linked signaling pathway	2.777995e-7
GO:0030155	regulation of cell adhesion	3.311518e-7
GO:2000145	regulation of cell motility	3.372909e-7
GO:0051349	positive regulation of lyase activity	3.405707e-7
GO:2000146	negative regulation of cell motility	3.590850e-7
GO:0009187	cyclic nucleotide metabolic process	3.937966e-7
GO:0030814	regulation of cAMP metabolic process	4.093717e-7
GO:0030334	regulation of cell migration	4.271774e-7
GO:0006140	regulation of nucleotide metabolic process	5.101948e-7
GO:0060346	bone trabecula formation	5.296617e-7
GO:0050794	regulation of cellular process	5.545917e-7
GO:0071496	cellular response to external stimulus	5.710673e-7
GO:0050920	regulation of chemotaxis	6.184098e-7
GO:0070887	cellular response to chemical stimulus	6.989176e-7
GO:0051339	regulation of lyase activity	8.541223e-7
GO:0051271	negative regulation of cellular component movement	8.592787e-7
GO:0050771	negative regulation of axonogenesis	1.008025e-6
GO:0050770	regulation of axonogenesis	1.045441e-6
GO:0007154	cell communication	1.053959e-6
GO:0030336	negative regulation of cell migration	1.209084e-6
GO:0050795	regulation of behavior	1.312180e-6
GO:0022604	regulation of cell morphogenesis	1.360488e-6
GO:0034097	response to cytokine stimulus	1.470805e-6
GO:0007189	activation of adenylate cyclase activity by G-protein signaling pathway	1.561889e-6
GO:0002684	positive regulation of immune system process	1.808559e-6
GO:0032963	collagen metabolic process	1.912664e-6
GO:0003231	cardiac ventricle development	2.132987e-6
GO:0070848	response to growth factor stimulus	2.355592e-6
GO:0003209	cardiac atrium morphogenesis	2.390232e-6
GO:0061081	positive regulation of myeloid leukocyte cytokine production involved in immune response	2.420657e-6
GO:0003230	cardiac atrium development	2.469369e-6
GO:0010812	negative regulation of cell-substrate adhesion	2.670457e-6
GO:0070208	protein heterotrimerization	2.753469e-6
GO:0002376	immune system process	2.824462e-6
GO:0071214	cellular response to abiotic stimulus	2.857392e-6
GO:0030825	positive regulation of cGMP metabolic process	2.922962e-6
GO:0045113	regulation of integrin biosynthetic process	3.072599e-6
GO:0032103	positive regulation of response to external stimulus	3.077575e-6
GO:0018879	biphenyl metabolic process	3.199773e-6
GO:0051049	regulation of transport	3.343656e-6
GO:0030098	lymphocyte differentiation	3.735908e-6
GO:0007191	activation of adenylate cyclase activity by dopamine receptor signaling pathway	4.122277e-6
GO:0003205	cardiac chamber development	4.925633e-6
GO:0014052	regulation of gamma-aminobutyric acid secretion	5.331669e-6
GO:0006928	cellular component movement	5.337118e-6
GO:0002702	positive regulation of production of molecular mediator of immune response	5.340552e-6
GO:0051716	cellular response to stimulus	5.657409e-6
GO:0055008	cardiac muscle tissue morphogenesis	6.058314e-6
GO:0030828	positive regulation of cGMP biosynthetic process	6.194311e-6
GO:0048841	regulation of axon extension involved in axon guidance	6.227103e-6
GO:0009190	cyclic nucleotide biosynthetic process	6.413210e-6
GO:0014809	regulation of skeletal muscle contraction by regulation of release of sequestered calcium ion	6.417319e-6
GO:0009605	response to external stimulus	6.460267e-6
GO:0032793	positive regulation of CREB transcription factor activity	6.934397e-6
GO:0019219	regulation of nucleobase-containing compound metabolic process	8.478652e-6
GO:0007129	synapsis	8.671057e-6
GO:0048539	bone marrow development	8.938380e-6
GO:0043516	regulation of DNA damage response, signal transduction by p53 class mediator	9.269506e-6
GO:0009612	response to mechanical stimulus	9.684829e-6
GO:0023052	signaling	9.958873e-6
GO:0046058	cAMP metabolic process	1.018470e-5
GO:0009956	radial pattern formation	1.026265e-5
GO:0032880	regulation of protein localization	1.051351e-5
GO:0021952	central nervous system projection neuron axonogenesis	1.113192e-5
GO:0016601	Rac protein signal transduction	1.147003e-5
GO:0045321	leukocyte activation	1.177532e-5
GO:0050776	regulation of immune response	1.185325e-5
GO:0030641	regulation of cellular pH	1.286130e-5
GO:0002906	negative regulation of mature B cell apoptosis	1.298715e-5
GO:0070192	chromosome organization involved in meiosis	1.328267e-5
GO:0040036	regulation of fibroblast growth factor receptor signaling pathway	1.375610e-5
GO:0032501	multicellular organismal process	1.400418e-5
GO:0016477	cell migration	1.586281e-5
GO:0051171	regulation of nitrogen compound metabolic process	1.847057e-5
GO:0009617	response to bacterium	1.917136e-5
GO:0048522	positive regulation of cellular process	2.000005e-5
GO:0042221	response to chemical stimulus	2.104231e-5
GO:0016358	dendrite development	2.142147e-5
GO:0003215	cardiac right ventricle morphogenesis	2.174824e-5
GO:0051128	regulation of cellular component organization	2.223841e-5
GO:0044259	multicellular organismal macromolecule metabolic process	2.308640e-5
GO:0050789	regulation of biological process	2.410043e-5
GO:0002237	response to molecule of bacterial origin	2.558966e-5
GO:0008582	regulation of synaptic growth at neuromuscular junction	2.625509e-5
GO:0007165	signal transduction	2.793932e-5
GO:0055093	response to hyperoxia	2.961403e-5
GO:0006909	phagocytosis	2.973001e-5
GO:0006116	NADH oxidation	2.986485e-5
GO:0032677	regulation of interleukin-8 production	3.135749e-5
GO:2001021	negative regulation of response to DNA damage stimulus	3.173862e-5
GO:0019935	cyclic-nucleotide-mediated signaling	3.262760e-5
GO:0042758	long-chain fatty acid catabolic process	3.331216e-5
GO:0042413	carnitine catabolic process	3.331216e-5
GO:0045346	regulation of MHC class II biosynthetic process	3.400633e-5
GO:0002697	regulation of immune effector process	3.600997e-5
GO:0051050	positive regulation of transport	3.641887e-5
GO:0010033	response to organic substance	3.644842e-5
GO:0040011	locomotion	3.875046e-5
GO:0030217	T cell differentiation	3.881126e-5
GO:0009258	10-formyltetrahydrofolate catabolic process	3.883589e-5
GO:0035556	intracellular signal transduction	4.089199e-5
GO:0045073	regulation of chemokine biosynthetic process	4.378848e-5
GO:0030801	positive regulation of cyclic nucleotide metabolic process	4.458190e-5
GO:0040037	negative regulation of fibroblast growth factor receptor signaling pathway	4.520754e-5
GO:2000353	positive regulation of endothelial cell apoptosis	4.840548e-5
GO:0051094	positive regulation of developmental process	5.090016e-5
GO:0019724	B cell mediated immunity	5.114020e-5
GO:0060907	positive regulation of macrophage cytokine production	5.126281e-5
GO:0007413	axonal fasciculation	5.230137e-5
GO:0016338	calcium-independent cell-cell adhesion	5.462324e-5
GO:0050778	positive regulation of immune response	5.465847e-5
GO:0046483	heterocycle metabolic process	5.716591e-5
GO:0048518	positive regulation of biological process	5.756879e-5
GO:0048869	cellular developmental process	5.761605e-5
GO:0007029	endoplasmic reticulum organization	5.778397e-5
GO:0046649	lymphocyte activation	5.829575e-5
GO:0032496	response to lipopolysaccharide	6.061889e-5
GO:0061138	morphogenesis of a branching epithelium	6.284064e-5
GO:0065007	biological regulation	6.364397e-5
GO:0007130	synaptonemal complex assembly	6.364904e-5
GO:0021602	cranial nerve morphogenesis	6.375913e-5
GO:0035803	egg coat formation	6.833507e-5
GO:0006702	androgen biosynthetic process	6.857958e-5
GO:0050867	positive regulation of cell activation	6.922302e-5
GO:0030154	cell differentiation	7.147535e-5
GO:0050922	negative regulation of chemotaxis	7.215141e-5
GO:0009123	nucleoside monophosphate metabolic process	7.230368e-5
GO:0014067	negative regulation of phosphatidylinositol 3-kinase cascade	7.489046e-5
GO:0006955	immune response	7.645284e-5
GO:0050921	positive regulation of chemotaxis	7.893392e-5
GO:0030855	epithelial cell differentiation	8.029962e-5
GO:0035621	ER to Golgi ceramide transport	8.422778e-5
GO:0032416	negative regulation of sodium:hydrogen antiporter activity	8.422778e-5
GO:0010959	regulation of metal ion transport	8.654887e-5
GO:0019933	cAMP-mediated signaling	8.796809e-5
GO:0048731	system development	8.813709e-5
GO:0016064	immunoglobulin mediated immune response	9.186877e-5
GO:0006917	induction of apoptosis	9.358049e-5
GO:0018963	phthalate metabolic process	9.530454e-5
GO:0009889	regulation of biosynthetic process	9.780697e-5
GO:0012502	induction of programmed cell death	9.898865e-5
GO:0080090	regulation of primary metabolic process	1.007516e-4
GO:0019541	propionate metabolic process	1.024678e-4
GO:0010596	negative regulation of endothelial cell migration	1.030849e-4
GO:0071732	cellular response to nitric oxide	1.034248e-4
GO:0048729	tissue morphogenesis	1.037160e-4
GO:0030823	regulation of cGMP metabolic process	1.042184e-4
GO:0030574	collagen catabolic process	1.057615e-4
GO:0032782	bile acid secretion	1.061986e-4
GO:0050928	negative regulation of positive chemotaxis	1.061986e-4
GO:0006285	base-excision repair, AP site formation	1.061986e-4
GO:0003096	renal sodium ion transport	1.061986e-4
GO:0032649	regulation of interferon-gamma production	1.085518e-4
GO:0060343	trabecula formation	1.095569e-4
GO:0002520	immune system development	1.111537e-4
GO:0010810	regulation of cell-substrate adhesion	1.201343e-4
GO:0032892	positive regulation of organic acid transport	1.231731e-4
GO:0002377	immunoglobulin production	1.241736e-4
GO:0002696	positive regulation of leukocyte activation	1.256560e-4
GO:0008038	neuron recognition	1.312580e-4
GO:0043518	negative regulation of DNA damage response, signal transduction by p53 class mediator	1.331198e-4
GO:0050877	neurological system process	1.360400e-4
GO:0019932	second-messenger-mediated signaling	1.384717e-4
GO:0048852	diencephalon morphogenesis	1.568173e-4
GO:0040017	positive regulation of locomotion	1.578292e-4
GO:0045359	positive regulation of interferon-beta biosynthetic process	1.592917e-4
GO:2000060	positive regulation of protein ubiquitination involved in ubiquitin-dependent protein catabolic process	1.655118e-4
GO:0001775	cell activation	1.657307e-4
GO:0043270	positive regulation of ion transport	1.676701e-4
GO:0043067	regulation of programmed cell death	1.696770e-4
GO:0048843	negative regulation of axon extension involved in axon guidance	1.697611e-4
GO:0002381	immunoglobulin production involved in immunoglobulin mediated immune response	1.752337e-4
GO:0007265	Ras protein signal transduction	1.896271e-4
GO:0035313	wound healing, spreading of epidermal cells	1.936567e-4
GO:0044236	multicellular organismal metabolic process	1.953343e-4
GO:0007188	G-protein signaling, coupled to cAMP nucleotide second messenger	1.957997e-4
GO:0010935	regulation of macrophage cytokine production	1.961998e-4
GO:0060070	canonical Wnt receptor signaling pathway	1.972084e-4
GO:0003008	system process	1.975595e-4
GO:0007254	JNK cascade	2.019341e-4
GO:0006145	purine base catabolic process	2.023945e-4
GO:2000147	positive regulation of cell motility	2.029794e-4
GO:0019227	neuronal action potential propagation	2.032769e-4
GO:0072521	purine-containing compound metabolic process	2.037360e-4
GO:0014053	negative regulation of gamma-aminobutyric acid secretion	2.050950e-4
GO:0007517	muscle organ development	2.053043e-4
GO:0033275	actin-myosin filament sliding	2.084013e-4
GO:0031326	regulation of cellular biosynthetic process	2.100067e-4
GO:0009117	nucleotide metabolic process	2.148299e-4
GO:0009115	xanthine catabolic process	2.156553e-4
GO:0030048	actin filament-based movement	2.244793e-4
GO:0019543	propionate catabolic process	2.311506e-4
GO:0009607	response to biotic stimulus	2.391214e-4
GO:0007187	G-protein signaling, coupled to cyclic nucleotide second messenger	2.408681e-4
GO:0071363	cellular response to growth factor stimulus	2.444738e-4
GO:0030198	extracellular matrix organization	2.448259e-4
GO:0032733	positive regulation of interleukin-10 production	2.510586e-4
GO:0015937	coenzyme A biosynthetic process	2.534883e-4
GO:0002449	lymphocyte mediated immunity	2.535872e-4
GO:2000008	regulation of protein localization at cell surface	2.591378e-4
GO:0048534	hemopoietic or lymphoid organ development	2.603358e-4
GO:0030804	positive regulation of cyclic nucleotide biosynthetic process	2.614043e-4
GO:0043589	skin morphogenesis	2.673196e-4
GO:0048739	cardiac muscle fiber development	2.774616e-4
GO:0009063	cellular amino acid catabolic process	2.775574e-4
GO:0060429	epithelium development	2.827162e-4
GO:0048870	cell motility	2.852541e-4
GO:0035987	endodermal cell differentiation	2.881843e-4
GO:0007162	negative regulation of cell adhesion	2.909648e-4
GO:0032502	developmental process	2.938041e-4
GO:0002687	positive regulation of leukocyte migration	2.942313e-4
GO:0001503	ossification	3.009261e-4
GO:0071310	cellular response to organic substance	3.050481e-4
GO:0060666	dichotomous subdivision of terminal units involved in salivary gland branching	3.100238e-4
GO:0048521	negative regulation of behavior	3.109195e-4
GO:0051223	regulation of protein transport	3.169772e-4
GO:0070925	organelle assembly	3.182662e-4
GO:0042110	T cell activation	3.211174e-4
GO:0002720	positive regulation of cytokine production involved in immune response	3.236633e-4
GO:0071731	response to nitric oxide	3.298277e-4
GO:0032972	regulation of muscle filament sliding speed	3.333358e-4
GO:0006427	histidyl-tRNA aminoacylation	3.333358e-4
GO:0045851	pH reduction	3.401764e-4
GO:0051272	positive regulation of cellular component movement	3.410826e-4
GO:0070201	regulation of establishment of protein localization	3.524046e-4
GO:0051452	intracellular pH reduction	3.544753e-4
GO:0018894	dibenzo-p-dioxin metabolic process	3.549962e-4
GO:0002921	negative regulation of humoral immune response	3.549962e-4
GO:0018026	peptidyl-lysine monomethylation	3.549962e-4
GO:0044319	wound healing, spreading of cells	3.587443e-4
GO:0043148	mitotic spindle stabilization	3.595013e-4
GO:0060415	muscle tissue morphogenesis	3.643798e-4
GO:0002440	production of molecular mediator of immune response	3.676556e-4
GO:0014706	striated muscle tissue development	3.714513e-4
GO:0002902	regulation of B cell apoptosis	3.787157e-4
GO:0030097	hemopoiesis	3.840980e-4
GO:0031929	TOR signaling cascade	3.888228e-4
GO:0001944	vasculature development	3.935492e-4
GO:0042176	regulation of protein catabolic process	4.033018e-4
GO:0051480	cytosolic calcium ion homeostasis	4.067302e-4
GO:0060539	diaphragm development	4.132903e-4
GO:0019674	NAD metabolic process	4.151283e-4
GO:0045080	positive regulation of chemokine biosynthetic process	4.194021e-4
GO:0009888	tissue development	4.216848e-4
GO:0022904	respiratory electron transport chain	4.252304e-4
GO:0048732	gland development	4.329636e-4
GO:0032890	regulation of organic acid transport	4.334033e-4
GO:0048812	neuron projection morphogenesis	4.367772e-4
GO:0006163	purine nucleotide metabolic process	4.447727e-4
GO:0032729	positive regulation of interferon-gamma production	4.500639e-4
GO:0001937	negative regulation of endothelial cell proliferation	4.507286e-4
GO:0030335	positive regulation of cell migration	4.609498e-4
GO:0051222	positive regulation of protein transport	4.630420e-4
GO:0042981	regulation of apoptosis	4.646452e-4
GO:0006734	NADH metabolic process	4.691208e-4
GO:0002521	leukocyte differentiation	4.738715e-4
GO:0035295	tube development	4.743223e-4
GO:0001714	endodermal cell fate specification	4.869856e-4
GO:0060236	regulation of mitotic spindle organization	4.879953e-4
GO:0015862	uridine transport	4.879953e-4
GO:0048295	positive regulation of isotype switching to IgE isotypes	4.976214e-4
GO:0032804	negative regulation of low-density lipoprotein particle receptor catabolic process	5.115842e-4
GO:0002443	leukocyte mediated immunity	5.206638e-4
GO:0051382	kinetochore assembly	5.219493e-4
GO:2001076	positive regulation of metanephric ureteric bud development	5.245860e-4
GO:0072302	negative regulation of metanephric glomerular mesangial cell proliferation	5.245860e-4
GO:0046168	glycerol-3-phosphate catabolic process	5.245860e-4
GO:0007356	thorax and anterior abdomen determination	5.245860e-4
GO:0034625	fatty acid elongation, monounsaturated fatty acid	5.475820e-4
GO:0032736	positive regulation of interleukin-13 production	5.475820e-4
GO:0031323	regulation of cellular metabolic process	5.531872e-4
GO:0010661	positive regulation of muscle cell apoptosis	5.605696e-4
GO:0035641	locomotory exploration behavior	5.670138e-4
GO:0022412	cellular process involved in reproduction in multicellular organism	5.730111e-4
GO:0030004	cellular monovalent inorganic cation homeostasis	5.741916e-4
GO:0048002	antigen processing and presentation of peptide antigen	5.744993e-4
GO:0006547	histidine metabolic process	5.800945e-4
GO:0051282	regulation of sequestering of calcium ion	5.941730e-4
GO:0030858	positive regulation of epithelial cell differentiation	5.942452e-4
GO:0001501	skeletal system development	6.015390e-4
GO:0050865	regulation of cell activation	6.063218e-4
GO:0002065	columnar/cuboidal epithelial cell differentiation	6.079187e-4
GO:0048513	organ development	6.102774e-4
GO:0043484	regulation of RNA splicing	6.132867e-4
GO:0006805	xenobiotic metabolic process	6.198305e-4
GO:0009410	response to xenobiotic stimulus	6.229584e-4
GO:0033605	positive regulation of catecholamine secretion	6.266643e-4
GO:0001936	regulation of endothelial cell proliferation	6.412552e-4
GO:0031349	positive regulation of defense response	6.498818e-4
GO:2000058	regulation of protein ubiquitination involved in ubiquitin-dependent protein catabolic process	6.571236e-4
GO:0008643	carbohydrate transport	6.629748e-4
GO:0031668	cellular response to extracellular stimulus	6.634410e-4
GO:0048520	positive regulation of behavior	6.667262e-4
GO:0070252	actin-mediated cell contraction	6.678696e-4
GO:0061383	trabecula morphogenesis	6.684605e-4
GO:0015816	glycine transport	6.751734e-4
GO:0050793	regulation of developmental process	6.758259e-4
GO:0048856	anatomical structure development	6.779489e-4
GO:0015876	acetyl-CoA transport	6.851190e-4
GO:0055086	nucleobase-containing small molecule metabolic process	7.241403e-4
GO:0051092	positive regulation of NF-kappaB transcription factor activity	7.271537e-4
GO:0002026	regulation of the force of heart contraction	7.494427e-4
GO:0048268	clathrin coat assembly	7.508412e-4
GO:0060675	ureteric bud morphogenesis	7.513715e-4
GO:0060676	ureteric bud formation	7.628639e-4
GO:0007626	locomotory behavior	8.276790e-4
GO:0060351	cartilage development involved in endochondral bone morphogenesis	8.296379e-4
GO:0007186	G-protein coupled receptor protein signaling pathway	8.300273e-4
GO:0019222	regulation of metabolic process	8.372698e-4
GO:0046068	cGMP metabolic process	8.439243e-4
GO:0032803	regulation of low-density lipoprotein particle receptor catabolic process	8.584619e-4
GO:0021631	optic nerve morphogenesis	8.669783e-4
GO:0045429	positive regulation of nitric oxide biosynthetic process	8.794370e-4
GO:0045597	positive regulation of cell differentiation	8.845427e-4
GO:0071560	cellular response to transforming growth factor beta stimulus	9.262331e-4
GO:0048305	immunoglobulin secretion	9.296245e-4
GO:0002252	immune effector process	9.304018e-4
GO:0060158	activation of phospholipase C activity by dopamine receptor signaling pathway	9.393798e-4
GO:0003056	regulation of vascular smooth muscle contraction	9.547248e-4
GO:0034341	response to interferon-gamma	9.655610e-4
GO:0018027	peptidyl-lysine dimethylation	9.719702e-4
GO:0003350	pulmonary myocardium development	9.719702e-4
GO:0072522	purine-containing compound biosynthetic process	9.832179e-4
GO:0002577	regulation of antigen processing and presentation	9.889701e-4
GO:0006901	vesicle coating	9.907438e-4
GO:0002924	negative regulation of humoral immune response mediated by circulating immunoglobulin	9.918705e-4
GO:0010468	regulation of gene expression	9.995709e-4
GO:0045732	positive regulation of protein catabolic process	1.001035e-3
GO:0006355	regulation of transcription, DNA-dependent	1.004431e-3
GO:0048584	positive regulation of response to stimulus	1.029555e-3
GO:0021559	trigeminal nerve development	1.032976e-3
GO:0046341	CDP-diacylglycerol metabolic process	1.037397e-3
GO:0032981	mitochondrial respiratory chain complex I assembly	1.044702e-3
GO:0045872	positive regulation of rhodopsin gene expression	1.046254e-3
GO:0019886	antigen processing and presentation of exogenous peptide antigen via MHC class II	1.052602e-3
GO:0048485	sympathetic nervous system development	1.054659e-3
GO:0002903	negative regulation of B cell apoptosis	1.056269e-3
GO:0005976	polysaccharide metabolic process	1.058967e-3
GO:2000171	negative regulation of dendrite development	1.070911e-3
GO:0060760	positive regulation of response to cytokine stimulus	1.077743e-3
GO:0050829	defense response to Gram-negative bacterium	1.077743e-3
GO:0060341	regulation of cellular localization	1.100333e-3
GO:0007204	elevation of cytosolic calcium ion concentration	1.103217e-3
GO:0061044	negative regulation of vascular wound healing	1.109807e-3
GO:2000098	negative regulation of smooth muscle cell-matrix adhesion	1.109807e-3
GO:0071258	cellular response to gravity	1.109807e-3
GO:0035491	positive regulation of leukotriene production involved in inflammatory response	1.109807e-3
GO:0030704	vitelline membrane formation	1.109807e-3
GO:0060325	face morphogenesis	1.110930e-3
GO:0006182	cGMP biosynthetic process	1.116370e-3
GO:0016055	Wnt receptor signaling pathway	1.119026e-3
GO:0006548	histidine catabolic process	1.133414e-3
GO:0030517	negative regulation of axon extension	1.134413e-3
GO:0032006	regulation of TOR signaling cascade	1.136756e-3
GO:0021636	trigeminal nerve morphogenesis	1.145300e-3
GO:0060348	bone development	1.160782e-3
GO:0006171	cAMP biosynthetic process	1.176265e-3
GO:0018931	naphthalene metabolic process	1.186278e-3
GO:0051454	intracellular pH elevation	1.199685e-3
GO:0032725	positive regulation of granulocyte macrophage colony-stimulating factor production	1.199685e-3
GO:0031642	negative regulation of myelination	1.199685e-3
GO:0006706	steroid catabolic process	1.201040e-3
GO:0070193	synaptonemal complex organization	1.204459e-3
GO:0043065	positive regulation of apoptosis	1.210975e-3
GO:0048747	muscle fiber development	1.221500e-3
GO:0071295	cellular response to vitamin	1.228943e-3
GO:0070584	mitochondrion morphogenesis	1.241542e-3
GO:0010594	regulation of endothelial cell migration	1.258839e-3
GO:0032101	regulation of response to external stimulus	1.260094e-3
GO:0010941	regulation of cell death	1.269301e-3
GO:0007167	enzyme linked receptor protein signaling pathway	1.272004e-3
GO:0002070	epithelial cell maturation	1.274874e-3
GO:0046395	carboxylic acid catabolic process	1.275259e-3
GO:0050906	detection of stimulus involved in sensory perception	1.280882e-3
GO:0034505	tooth mineralization	1.289614e-3
GO:0002064	epithelial cell development	1.290430e-3
GO:0060600	dichotomous subdivision of an epithelial terminal unit	1.298367e-3
GO:0019319	hexose biosynthetic process	1.308483e-3
GO:0010543	regulation of platelet activation	1.317662e-3
GO:0046686	response to cadmium ion	1.329589e-3
GO:0072358	cardiovascular system development	1.336274e-3
GO:0048640	negative regulation of developmental growth	1.362326e-3
GO:0070593	dendrite self-avoidance	1.380032e-3
GO:0071345	cellular response to cytokine stimulus	1.383216e-3
GO:0046822	regulation of nucleocytoplasmic transport	1.385556e-3
GO:0002604	regulation of dendritic cell antigen processing and presentation	1.390576e-3
GO:0051954	positive regulation of amine transport	1.390576e-3
GO:0048013	ephrin receptor signaling pathway	1.402081e-3
GO:0051252	regulation of RNA metabolic process	1.402858e-3
GO:0003170	heart valve development	1.404683e-3
GO:0042330	taxis	1.404771e-3
GO:0048568	embryonic organ development	1.433161e-3
GO:0070372	regulation of ERK1 and ERK2 cascade	1.441421e-3
GO:0007275	multicellular organismal development	1.449073e-3
GO:0001738	morphogenesis of a polarized epithelium	1.470789e-3
GO:0001711	endodermal cell fate commitment	1.482963e-3
GO:0006352	transcription initiation, DNA-dependent	1.520483e-3
GO:0060537	muscle tissue development	1.527041e-3
GO:0032735	positive regulation of interleukin-12 production	1.537028e-3
GO:0001568	blood vessel development	1.553978e-3
GO:0032386	regulation of intracellular transport	1.557136e-3
GO:0001763	morphogenesis of a branching structure	1.580577e-3
GO:0009628	response to abiotic stimulus	1.586521e-3
GO:0050433	regulation of catecholamine secretion	1.586852e-3
GO:0030514	negative regulation of BMP signaling pathway	1.588788e-3
GO:0007218	neuropeptide signaling pathway	1.595517e-3
GO:0002066	columnar/cuboidal epithelial cell development	1.596920e-3
GO:0002830	positive regulation of type 2 immune response	1.606929e-3
GO:0050885	neuromuscular process controlling balance	1.620068e-3
GO:0043068	positive regulation of programmed cell death	1.628589e-3
GO:0000380	alternative nuclear mRNA splicing, via spliceosome	1.643613e-3
GO:0060538	skeletal muscle organ development	1.643871e-3
GO:0006935	chemotaxis	1.647972e-3
GO:0010721	negative regulation of cell development	1.649154e-3
GO:0006979	response to oxidative stress	1.653854e-3
GO:0006213	pyrimidine nucleoside metabolic process	1.656182e-3
GO:0051291	protein heterooligomerization	1.659478e-3
GO:0006164	purine nucleotide biosynthetic process	1.673385e-3
GO:0045792	negative regulation of cell size	1.685747e-3
GO:2000106	regulation of leukocyte apoptosis	1.702096e-3
GO:0008361	regulation of cell size	1.713917e-3
GO:0001764	neuron migration	1.724757e-3
GO:0090096	positive regulation of metanephric cap mesenchymal cell proliferation	1.754111e-3
GO:0046110	xanthine metabolic process	1.754111e-3
GO:0035691	macrophage migration inhibitory factor signaling pathway	1.754111e-3
GO:0008037	cell recognition	1.768887e-3
GO:0030203	glycosaminoglycan metabolic process	1.769256e-3
GO:0021955	central nervous system neuron axonogenesis	1.769695e-3
GO:0045357	regulation of interferon-beta biosynthetic process	1.773123e-3
GO:0032236	positive regulation of calcium ion transport via store-operated calcium channel activity	1.779050e-3
GO:0032964	collagen biosynthetic process	1.780593e-3
GO:0046034	ATP metabolic process	1.790514e-3
GO:0000165	MAPKKK cascade	1.796139e-3
GO:0030183	B cell differentiation	1.820629e-3
GO:0006534	cysteine metabolic process	1.858124e-3
GO:0048708	astrocyte differentiation	1.862840e-3
GO:2000026	regulation of multicellular organismal development	1.881612e-3
GO:0032757	positive regulation of interleukin-8 production	1.904950e-3
GO:0042178	xenobiotic catabolic process	1.919203e-3
GO:0060307	regulation of ventricular cardiomyocyte membrane repolarization	1.923296e-3
GO:0060299	negative regulation of sarcomere organization	1.923296e-3
GO:0015761	mannose transport	1.923296e-3
GO:0033314	mitotic cell cycle DNA replication checkpoint	1.923296e-3
GO:0017196	N-terminal peptidyl-methionine acetylation	1.923296e-3
GO:0002685	regulation of leukocyte migration	1.928803e-3
GO:0010717	regulation of epithelial to mesenchymal transition	1.929289e-3
GO:0034393	positive regulation of smooth muscle cell apoptosis	1.933803e-3
GO:0051453	regulation of intracellular pH	1.951775e-3
GO:0019254	carnitine metabolic process, CoA-linked	1.953067e-3
GO:0014054	positive regulation of gamma-aminobutyric acid secretion	1.964955e-3
GO:0006072	glycerol-3-phosphate metabolic process	1.964955e-3
GO:0003007	heart morphogenesis	1.984184e-3
GO:0048523	negative regulation of cellular process	1.991734e-3
GO:0030534	adult behavior	1.992529e-3
GO:0032760	positive regulation of tumor necrosis factor production	2.018189e-3
GO:0031346	positive regulation of cell projection organization	2.026631e-3
GO:0003179	heart valve morphogenesis	2.043573e-3
GO:0048705	skeletal system morphogenesis	2.045500e-3
GO:0002572	pro-T cell differentiation	2.058611e-3
GO:0070474	positive regulation of uterine smooth muscle contraction	2.058611e-3
GO:0044270	cellular nitrogen compound catabolic process	2.080024e-3
GO:0002579	positive regulation of antigen processing and presentation	2.085456e-3
GO:0051924	regulation of calcium ion transport	2.087340e-3
GO:0009214	cyclic nucleotide catabolic process	2.092747e-3
GO:0031670	cellular response to nutrient	2.111167e-3
GO:0043537	negative regulation of blood vessel endothelial cell migration	2.139145e-3
GO:0051251	positive regulation of lymphocyte activation	2.143434e-3
GO:0032206	positive regulation of telomere maintenance	2.162103e-3
GO:0001692	histamine metabolic process	2.162103e-3
GO:0045414	regulation of interleukin-8 biosynthetic process	2.192585e-3
GO:0050432	catecholamine secretion	2.212634e-3