Novel motif:125

name:	motif125_TTTAACTCGT

Association to promoter expression in human samples<b>Summary:</b>Significance of the correlation with CAGE expression, human <br><b>Analyst:</b> Michiel de Hoon<br><br>link to source dataset <br>data

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Association to promoter expression in mouse samples <b>Summary:</b>Significance of the correlation with CAGE expression, mouse <br><b>Analyst:</b> Michiel de Hoon<br><br>link to source dataset <br>data

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GREAT analysis results for human <b>Summary:</b>Genomic Enrichment of Annotations Tool (GREAT, Nat Biotechnol. 2010 May;28(5):495-501) is used to identify, both in human and in mouse, the gene ontology terms of biological processes enriched given the predicted TFBSs, and evaluated the overlap in the top-500 gene ontology terms between human and mouse. For each novel motif, the P value for the overlap was then evaluated by calculating its relative rank with respect to this background distribution.<br>Analyst: Michiel de Hoon<br><br>link to source dataset <br>data

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GO ID	GO Term	p-value
GO:0045137	development of primary sexual characteristics	9.071500e-9
GO:0035845	photoreceptor cell outer segment organization	2.920364e-8
GO:0009799	specification of symmetry	6.826723e-8
GO:0007368	determination of left/right symmetry	7.220677e-8
GO:0009855	determination of bilateral symmetry	9.488340e-8
GO:0030828	positive regulation of cGMP biosynthetic process	1.796383e-7
GO:0043252	sodium-independent organic anion transport	2.019459e-7
GO:0045981	positive regulation of nucleotide metabolic process	2.039902e-7
GO:0050925	negative regulation of negative chemotaxis	2.263792e-7
GO:0042094	interleukin-2 biosynthetic process	2.508267e-7
GO:0006970	response to osmotic stress	2.760853e-7
GO:0003127	detection of nodal flow	3.134171e-7
GO:0015742	alpha-ketoglutarate transport	3.885126e-7
GO:0045175	basal protein localization	3.885126e-7
GO:0042176	regulation of protein catabolic process	5.291033e-7
GO:0031427	response to methotrexate	6.050227e-7
GO:0007548	sex differentiation	6.953583e-7
GO:0042221	response to chemical stimulus	7.774146e-7
GO:0061136	regulation of proteasomal protein catabolic process	1.230560e-6
GO:0060807	regulation of transcription from RNA polymerase II promoter involved in definitive endodermal cell fate specification	1.496745e-6
GO:0003142	cardiogenic plate morphogenesis	1.496745e-6
GO:0030801	positive regulation of cyclic nucleotide metabolic process	1.782279e-6
GO:0042986	positive regulation of amyloid precursor protein biosynthetic process	2.227923e-6
GO:0008207	C21-steroid hormone metabolic process	2.311916e-6
GO:0031508	centromeric heterochromatin formation	2.438784e-6
GO:0030804	positive regulation of cyclic nucleotide biosynthetic process	2.491413e-6
GO:0048608	reproductive structure development	3.838058e-6
GO:0046545	development of primary female sexual characteristics	4.037240e-6
GO:0008406	gonad development	4.127611e-6
GO:0060164	regulation of timing of neuron differentiation	4.130513e-6
GO:0035239	tube morphogenesis	4.636534e-6
GO:0048685	negative regulation of collateral sprouting of intact axon in response to injury	4.708765e-6
GO:0032488	Cdc42 protein signal transduction	5.166676e-6
GO:0046548	retinal rod cell development	5.556978e-6
GO:0000186	activation of MAPKK activity	5.793228e-6
GO:0060658	nipple morphogenesis	7.099159e-6
GO:0070541	response to platinum ion	7.681249e-6
GO:0019836	hemolysis by symbiont of host erythrocytes	8.735874e-6
GO:0030826	regulation of cGMP biosynthetic process	1.099819e-5
GO:0009410	response to xenobiotic stimulus	1.125497e-5
GO:0046660	female sex differentiation	1.135556e-5
GO:0048662	negative regulation of smooth muscle cell proliferation	1.220088e-5
GO:0021764	amygdala development	1.300343e-5
GO:0042448	progesterone metabolic process	1.306600e-5
GO:0030825	positive regulation of cGMP metabolic process	1.364710e-5
GO:0090096	positive regulation of metanephric cap mesenchymal cell proliferation	1.441939e-5
GO:0010985	negative regulation of lipoprotein particle clearance	1.496403e-5
GO:0031647	regulation of protein stability	1.498130e-5
GO:0032803	regulation of low-density lipoprotein particle receptor catabolic process	1.536826e-5
GO:0051659	maintenance of mitochondrion location	1.553090e-5
GO:0046010	positive regulation of circadian sleep/wake cycle, non-REM sleep	1.553090e-5
GO:0016199	axon midline choice point recognition	1.619497e-5
GO:0006805	xenobiotic metabolic process	1.948356e-5
GO:0034048	negative regulation of protein phosphatase type 2A activity	1.952553e-5
GO:0014048	regulation of glutamate secretion	2.158205e-5
GO:0030162	regulation of proteolysis	2.202321e-5
GO:0015711	organic anion transport	2.344617e-5
GO:0032623	interleukin-2 production	2.380925e-5
GO:0033700	phospholipid efflux	2.389379e-5
GO:0045023	G0 to G1 transition	2.436064e-5
GO:0065008	regulation of biological quality	2.701509e-5
GO:0071466	cellular response to xenobiotic stimulus	2.748301e-5
GO:0034377	plasma lipoprotein particle assembly	2.753563e-5
GO:0008202	steroid metabolic process	2.817828e-5
GO:0050923	regulation of negative chemotaxis	2.937125e-5
GO:0050821	protein stabilization	2.981058e-5
GO:0070986	left/right axis specification	3.100771e-5
GO:0042984	regulation of amyloid precursor protein biosynthetic process	3.360941e-5
GO:0010916	negative regulation of very-low-density lipoprotein particle clearance	3.458333e-5
GO:0009726	detection of endogenous stimulus	3.796738e-5
GO:0032805	positive regulation of low-density lipoprotein particle receptor catabolic process	4.339885e-5
GO:0009386	translational attenuation	4.339885e-5
GO:0060562	epithelial tube morphogenesis	4.361283e-5
GO:0045732	positive regulation of protein catabolic process	4.660601e-5
GO:0000715	nucleotide-excision repair, DNA damage recognition	4.686373e-5
GO:0010560	positive regulation of glycoprotein biosynthetic process	5.119055e-5
GO:0001654	eye development	5.179272e-5
GO:0034380	high-density lipoprotein particle assembly	5.232831e-5
GO:0032434	regulation of proteasomal ubiquitin-dependent protein catabolic process	5.383790e-5
GO:0009584	detection of visible light	5.455642e-5
GO:0017186	peptidyl-pyroglutamic acid biosynthetic process, using glutaminyl-peptide cyclotransferase	5.761211e-5
GO:0007500	mesodermal cell fate determination	5.787660e-5
GO:0030218	erythrocyte differentiation	5.875628e-5
GO:0050983	deoxyhypusine biosynthetic process from spermidine, using deoxyhypusine synthase	6.357774e-5
GO:0042159	lipoprotein catabolic process	6.810395e-5
GO:0060649	mammary gland bud elongation	6.862711e-5
GO:0060659	nipple sheath formation	6.862711e-5
GO:0001578	microtubule bundle formation	7.354272e-5
GO:0045938	positive regulation of circadian sleep/wake cycle, sleep	7.357801e-5
GO:0042662	negative regulation of mesodermal cell fate specification	7.744450e-5
GO:0043507	positive regulation of JUN kinase activity	7.983043e-5
GO:0019748	secondary metabolic process	8.697199e-5
GO:0007168	receptor guanylyl cyclase signaling pathway	9.520447e-5
GO:0007603	phototransduction, visible light	9.687373e-5
GO:2000741	positive regulation of mesenchymal stem cell differentiation	9.799232e-5
GO:0042089	cytokine biosynthetic process	9.843252e-5
GO:0009404	toxin metabolic process	1.013729e-4
GO:0044248	cellular catabolic process	1.073931e-4
GO:0060041	retina development in camera-type eye	1.078896e-4
GO:0060956	endocardial cell differentiation	1.094238e-4
GO:0034754	cellular hormone metabolic process	1.112909e-4
GO:0060123	regulation of growth hormone secretion	1.283537e-4
GO:0016098	monoterpenoid metabolic process	1.313532e-4
GO:0050995	negative regulation of lipid catabolic process	1.337406e-4
GO:0072523	purine-containing compound catabolic process	1.409151e-4
GO:0010984	regulation of lipoprotein particle clearance	1.409356e-4
GO:0040019	positive regulation of embryonic development	1.506381e-4
GO:0034655	nucleobase-containing compound catabolic process	1.513471e-4
GO:0008585	female gonad development	1.573448e-4
GO:0003006	developmental process involved in reproduction	1.575818e-4
GO:0002244	hemopoietic progenitor cell differentiation	1.641388e-4
GO:0009056	catabolic process	1.648937e-4
GO:0034101	erythrocyte homeostasis	1.662522e-4
GO:0030728	ovulation	1.663579e-4
GO:0021891	olfactory bulb interneuron development	1.705192e-4
GO:0048505	regulation of timing of cell differentiation	1.778369e-4
GO:0051005	negative regulation of lipoprotein lipase activity	1.822129e-4
GO:0051004	regulation of lipoprotein lipase activity	1.875325e-4
GO:0034379	very-low-density lipoprotein particle assembly	2.029842e-4
GO:0042157	lipoprotein metabolic process	2.048173e-4
GO:0050774	negative regulation of dendrite morphogenesis	2.128113e-4
GO:0060075	regulation of resting membrane potential	2.128113e-4
GO:0034047	regulation of protein phosphatase type 2A activity	2.128113e-4
GO:0015938	coenzyme A catabolic process	2.211732e-4
GO:0048683	regulation of collateral sprouting of intact axon in response to injury	2.251143e-4
GO:0034105	positive regulation of tissue remodeling	2.376338e-4
GO:0051657	maintenance of organelle location	2.422274e-4
GO:0060913	cardiac cell fate determination	2.474573e-4
GO:0014740	negative regulation of muscle hyperplasia	2.715067e-4
GO:0043010	camera-type eye development	2.739500e-4
GO:0050896	response to stimulus	2.781422e-4
GO:0010873	positive regulation of cholesterol esterification	2.842111e-4
GO:0010716	negative regulation of extracellular matrix disassembly	2.872411e-4
GO:0030823	regulation of cGMP metabolic process	2.956256e-4
GO:0002053	positive regulation of mesenchymal cell proliferation	3.059110e-4
GO:0006195	purine nucleotide catabolic process	3.106704e-4
GO:0035295	tube development	3.162781e-4
GO:0043506	regulation of JUN kinase activity	3.296115e-4
GO:0055096	low-density lipoprotein particle mediated signaling	3.314342e-4
GO:0051240	positive regulation of multicellular organismal process	3.357531e-4
GO:0061039	ovum-producing ovary development	3.415781e-4
GO:0015904	tetracycline transport	3.450185e-4
GO:0021836	chemorepulsion involved in postnatal olfactory bulb interneuron migration	3.483078e-4
GO:0001893	maternal placenta development	3.574520e-4
GO:0007507	heart development	3.583897e-4
GO:0032501	multicellular organismal process	3.863843e-4
GO:0010107	potassium ion import	3.905495e-4
GO:2000739	regulation of mesenchymal stem cell differentiation	3.970626e-4
GO:0006820	anion transport	4.498297e-4
GO:0042107	cytokine metabolic process	4.717208e-4
GO:0006811	ion transport	4.771401e-4
GO:0045541	negative regulation of cholesterol biosynthetic process	4.813545e-4
GO:0021870	Cajal-Retzius cell differentiation	4.813545e-4
GO:0009166	nucleotide catabolic process	4.821362e-4
GO:0005983	starch catabolic process	4.960396e-4
GO:0060968	regulation of gene silencing	5.005182e-4
GO:0043401	steroid hormone mediated signaling pathway	5.030119e-4
GO:0060324	face development	5.034037e-4
GO:0016198	axon choice point recognition	5.085443e-4
GO:0046700	heterocycle catabolic process	5.138806e-4
GO:0051563	smooth endoplasmic reticulum calcium ion homeostasis	5.307370e-4
GO:0034508	centromere complex assembly	5.307370e-4
GO:0014738	regulation of muscle hyperplasia	5.366959e-4
GO:0050860	negative regulation of T cell receptor signaling pathway	5.422638e-4
GO:0070493	thrombin receptor signaling pathway	5.474316e-4
GO:0051919	positive regulation of fibrinolysis	5.621862e-4
GO:0070561	vitamin D receptor signaling pathway	5.621862e-4
GO:0090184	positive regulation of kidney development	5.728997e-4
GO:0002576	platelet degranulation	5.966573e-4
GO:0003108	negative regulation of the force of heart contraction by chemical signal	5.991802e-4
GO:0009082	branched chain family amino acid biosynthetic process	6.001493e-4
GO:0046689	response to mercury ion	6.015314e-4
GO:0008105	asymmetric protein localization	6.033757e-4
GO:0001655	urogenital system development	6.041391e-4
GO:0000381	regulation of alternative nuclear mRNA splicing, via spliceosome	6.108096e-4
GO:0002639	positive regulation of immunoglobulin production	6.225533e-4
GO:0060322	head development	6.238040e-4
GO:0030540	female genitalia development	6.449141e-4
GO:0010980	positive regulation of vitamin D 24-hydroxylase activity	6.522037e-4
GO:0060823	canonical Wnt receptor signaling pathway involved in neural plate anterior/posterior pattern formation	6.540602e-4
GO:0022607	cellular component assembly	6.666421e-4
GO:0007492	endoderm development	6.813042e-4
GO:0044270	cellular nitrogen compound catabolic process	6.848429e-4
GO:0010464	regulation of mesenchymal cell proliferation	6.916800e-4
GO:0060795	cell fate commitment involved in formation of primary germ layers	7.002123e-4
GO:0072001	renal system development	7.140391e-4
GO:0034244	negative regulation of transcription elongation from RNA polymerase II promoter	7.285359e-4
GO:0014745	negative regulation of muscle adaptation	7.285359e-4
GO:0009996	negative regulation of cell fate specification	7.384007e-4
GO:0002320	lymphoid progenitor cell differentiation	7.456298e-4
GO:0021772	olfactory bulb development	7.497648e-4
GO:0010900	negative regulation of phosphatidylcholine catabolic process	7.519691e-4
GO:0071233	cellular response to leucine	7.519691e-4
GO:0010587	miRNA catabolic process	7.519691e-4
GO:0001711	endodermal cell fate commitment	8.135530e-4
GO:0048024	regulation of nuclear mRNA splicing, via spliceosome	8.180961e-4
GO:0051716	cellular response to stimulus	8.381532e-4
GO:0010216	maintenance of DNA methylation	8.423904e-4
GO:0043114	regulation of vascular permeability	8.432188e-4
GO:0010559	regulation of glycoprotein biosynthetic process	8.567851e-4
GO:0003157	endocardium development	8.643439e-4
GO:0045995	regulation of embryonic development	8.673984e-4
GO:0060136	embryonic process involved in female pregnancy	8.830289e-4
GO:0003057	regulation of the force of heart contraction by chemical signal	8.830289e-4
GO:0030799	regulation of cyclic nucleotide metabolic process	8.884219e-4
GO:0045197	establishment or maintenance of epithelial cell apical/basal polarity	9.526413e-4
GO:0006163	purine nucleotide metabolic process	9.546891e-4
GO:0051017	actin filament bundle assembly	9.917713e-4
GO:0072521	purine-containing compound metabolic process	9.968027e-4
GO:0007512	adult heart development	1.004723e-3
GO:0022603	regulation of anatomical structure morphogenesis	1.027903e-3
GO:0050890	cognition	1.030824e-3
GO:0035556	intracellular signal transduction	1.038146e-3
GO:0010811	positive regulation of cell-substrate adhesion	1.039736e-3
GO:0006642	triglyceride mobilization	1.043763e-3
GO:0031640	killing of cells of other organism	1.045316e-3
GO:0070997	neuron death	1.048246e-3
GO:0044273	sulfur compound catabolic process	1.055564e-3
GO:0007263	nitric oxide mediated signal transduction	1.059505e-3
GO:0016998	cell wall macromolecule catabolic process	1.063069e-3
GO:0051016	barbed-end actin filament capping	1.083805e-3
GO:0051172	negative regulation of nitrogen compound metabolic process	1.090165e-3
GO:0006857	oligopeptide transport	1.091510e-3
GO:0043542	endothelial cell migration	1.092093e-3
GO:0042462	eye photoreceptor cell development	1.096226e-3
GO:0042738	exogenous drug catabolic process	1.110810e-3
GO:0061031	endodermal digestive tract morphogenesis	1.144957e-3
GO:0043584	nose development	1.181017e-3
GO:0060972	left/right pattern formation	1.187133e-3
GO:0031330	negative regulation of cellular catabolic process	1.194386e-3
GO:0007628	adult walking behavior	1.199858e-3
GO:2000058	regulation of protein ubiquitination involved in ubiquitin-dependent protein catabolic process	1.235849e-3
GO:0002328	pro-B cell differentiation	1.235849e-3
GO:0007015	actin filament organization	1.252931e-3
GO:2000334	positive regulation of blood microparticle formation	1.253419e-3
GO:0071674	mononuclear cell migration	1.259804e-3
GO:0097006	regulation of plasma lipoprotein particle levels	1.340758e-3
GO:0051883	killing of cells in other organism involved in symbiotic interaction	1.371459e-3
GO:0044003	modification by symbiont of host morphology or physiology	1.374320e-3
GO:0048660	regulation of smooth muscle cell proliferation	1.395176e-3
GO:0044036	cell wall macromolecule metabolic process	1.413785e-3
GO:0003357	noradrenergic neuron differentiation	1.421266e-3
GO:0048643	positive regulation of skeletal muscle tissue development	1.434623e-3
GO:0046546	development of primary male sexual characteristics	1.436824e-3
GO:0071603	endothelial cell-cell adhesion	1.440318e-3
GO:0022602	ovulation cycle process	1.455670e-3
GO:0007231	osmosensory signaling pathway	1.477389e-3
GO:0035082	axoneme assembly	1.500723e-3
GO:0042461	photoreceptor cell development	1.524434e-3
GO:0060214	endocardium formation	1.533233e-3
GO:0021889	olfactory bulb interneuron differentiation	1.537484e-3
GO:0033135	regulation of peptidyl-serine phosphorylation	1.544496e-3
GO:0035088	establishment or maintenance of apical/basal cell polarity	1.551640e-3
GO:0001542	ovulation from ovarian follicle	1.551640e-3
GO:0021978	telencephalon regionalization	1.567954e-3
GO:0007256	activation of JNKK activity	1.570802e-3
GO:0006367	transcription initiation from RNA polymerase II promoter	1.584751e-3
GO:0019367	fatty acid elongation, saturated fatty acid	1.599793e-3
GO:0072075	metanephric mesenchyme development	1.611684e-3
GO:0002329	pre-B cell differentiation	1.625097e-3
GO:0014009	glial cell proliferation	1.631019e-3
GO:0046649	lymphocyte activation	1.645266e-3
GO:0032436	positive regulation of proteasomal ubiquitin-dependent protein catabolic process	1.677434e-3
GO:0009187	cyclic nucleotide metabolic process	1.713083e-3
GO:0034625	fatty acid elongation, monounsaturated fatty acid	1.729480e-3
GO:0009896	positive regulation of catabolic process	1.731575e-3
GO:0060541	respiratory system development	1.732312e-3
GO:0043949	regulation of cAMP-mediated signaling	1.752694e-3
GO:0018199	peptidyl-glutamine modification	1.784051e-3
GO:0006641	triglyceride metabolic process	1.790807e-3
GO:0042445	hormone metabolic process	1.800696e-3
GO:0045780	positive regulation of bone resorption	1.804942e-3
GO:0034765	regulation of ion transmembrane transport	1.805343e-3
GO:0010817	regulation of hormone levels	1.815449e-3
GO:0010872	regulation of cholesterol esterification	1.819430e-3
GO:0051646	mitochondrion localization	1.822162e-3
GO:0046549	retinal cone cell development	1.839463e-3
GO:0030183	B cell differentiation	1.841168e-3
GO:0044085	cellular component biogenesis	1.912286e-3
GO:0031122	cytoplasmic microtubule organization	1.927129e-3
GO:0023052	signaling	1.932723e-3
GO:0033152	immunoglobulin V(D)J recombination	1.940706e-3
GO:0046697	decidualization	1.947791e-3
GO:0010989	negative regulation of low-density lipoprotein particle clearance	1.968736e-3
GO:0032147	activation of protein kinase activity	1.981038e-3
GO:0048617	embryonic foregut morphogenesis	1.981063e-3
GO:0035810	positive regulation of urine volume	1.993546e-3
GO:0045934	negative regulation of nucleobase-containing compound metabolic process	2.018684e-3
GO:0007565	female pregnancy	2.031670e-3
GO:0042753	positive regulation of circadian rhythm	2.031901e-3
GO:0003018	vascular process in circulatory system	2.093447e-3
GO:0035634	response to stilbenoid	2.107993e-3
GO:0014049	positive regulation of glutamate secretion	2.118906e-3
GO:0021827	postnatal olfactory bulb interneuron migration	2.164791e-3
GO:0042737	drug catabolic process	2.189879e-3
GO:0060648	mammary gland bud morphogenesis	2.189879e-3
GO:0015672	monovalent inorganic cation transport	2.241718e-3
GO:0008344	adult locomotory behavior	2.256068e-3
GO:0032608	interferon-beta production	2.269548e-3
GO:0071447	cellular response to hydroperoxide	2.326168e-3
GO:0045862	positive regulation of proteolysis	2.393960e-3
GO:0061036	positive regulation of cartilage development	2.441052e-3
GO:0043438	acetoacetic acid metabolic process	2.543528e-3
GO:0010033	response to organic substance	2.563327e-3
GO:2000121	regulation of removal of superoxide radicals	2.575980e-3
GO:0015813	L-glutamate transport	2.579535e-3
GO:0051043	regulation of membrane protein ectodomain proteolysis	2.595552e-3
GO:0045188	regulation of circadian sleep/wake cycle, non-REM sleep	2.604902e-3
GO:0010629	negative regulation of gene expression	2.629988e-3
GO:0001701	in utero embryonic development	2.658236e-3
GO:0051925	regulation of calcium ion transport via voltage-gated calcium channel activity	2.658252e-3
GO:0010470	regulation of gastrulation	2.671444e-3
GO:0002702	positive regulation of production of molecular mediator of immune response	2.672805e-3
GO:0015911	plasma membrane long-chain fatty acid transport	2.674884e-3
GO:0016447	somatic recombination of immunoglobulin gene segments	2.695300e-3
GO:0051253	negative regulation of RNA metabolic process	2.709345e-3
GO:0045922	negative regulation of fatty acid metabolic process	2.739814e-3
GO:0000003	reproduction	2.784626e-3
GO:0021517	ventral spinal cord development	2.859508e-3
GO:0021800	cerebral cortex tangential migration	2.882682e-3
GO:0007254	JNK cascade	2.948866e-3
GO:0034384	high-density lipoprotein particle clearance	3.041409e-3
GO:0031327	negative regulation of cellular biosynthetic process	3.050103e-3
GO:0002521	leukocyte differentiation	3.067705e-3
GO:0042698	ovulation cycle	3.091375e-3
GO:0001507	acetylcholine catabolic process in synaptic cleft	3.101242e-3
GO:0042412	taurine biosynthetic process	3.188279e-3
GO:0007610	behavior	3.223562e-3
GO:0046661	male sex differentiation	3.244358e-3
GO:0042113	B cell activation	3.309193e-3
GO:0022414	reproductive process	3.374982e-3
GO:0065003	macromolecular complex assembly	3.422774e-3
GO:0006638	neutral lipid metabolic process	3.437973e-3
GO:0060840	artery development	3.455394e-3
GO:0008206	bile acid metabolic process	3.459256e-3
GO:0001714	endodermal cell fate specification	3.461225e-3
GO:0050789	regulation of biological process	3.481966e-3
GO:0061188	negative regulation of chromatin silencing at rDNA	3.486533e-3
GO:0030263	apoptotic chromosome condensation	3.486533e-3
GO:0001947	heart looping	3.512872e-3
GO:2000758	positive regulation of peptidyl-lysine acetylation	3.543290e-3
GO:0048806	genitalia development	3.568159e-3
GO:2000027	regulation of organ morphogenesis	3.576259e-3
GO:0090136	epithelial cell-cell adhesion	3.588292e-3
GO:0014050	negative regulation of glutamate secretion	3.588292e-3
GO:0006730	one-carbon metabolic process	3.596163e-3
GO:0019934	cGMP-mediated signaling	3.607149e-3
GO:2000761	positive regulation of N-terminal peptidyl-lysine acetylation	3.610522e-3
GO:0035910	ascending aorta morphogenesis	3.610522e-3
GO:0034333	adherens junction assembly	3.619189e-3
GO:0002709	regulation of T cell mediated immunity	3.630721e-3
GO:0071844	cellular component assembly at cellular level	3.639303e-3
GO:0032330	regulation of chondrocyte differentiation	3.674549e-3
GO:0006639	acylglycerol metabolic process	3.696403e-3
GO:0050916	sensory perception of sweet taste	3.710215e-3
GO:0030910	olfactory placode formation	3.710215e-3
GO:0042661	regulation of mesodermal cell fate specification	3.727506e-3
GO:0009892	negative regulation of metabolic process	3.773705e-3
GO:0009143	nucleoside triphosphate catabolic process	3.774652e-3
GO:0009207	purine ribonucleoside triphosphate catabolic process	3.788132e-3
GO:2000059	negative regulation of protein ubiquitination involved in ubiquitin-dependent protein catabolic process	3.799353e-3
GO:0035771	interleukin-4-mediated signaling pathway	3.799353e-3
GO:0033239	negative regulation of cellular amine metabolic process	3.799353e-3
GO:0010038	response to metal ion	3.806837e-3
GO:0016445	somatic diversification of immunoglobulins	3.846156e-3
GO:0030099	myeloid cell differentiation	3.887819e-3
GO:0007584	response to nutrient	3.895982e-3
GO:0051592	response to calcium ion	3.904035e-3
GO:0000718	nucleotide-excision repair, DNA damage removal	3.904682e-3
GO:0031123	RNA 3'-end processing	3.908878e-3
GO:0001775	cell activation	3.909615e-3
GO:0015800	acidic amino acid transport	3.917335e-3
GO:0003007	heart morphogenesis	3.947758e-3
GO:0032735	positive regulation of interleukin-12 production	3.987909e-3
GO:0030802	regulation of cyclic nucleotide biosynthetic process	3.989960e-3
GO:0006182	cGMP biosynthetic process	4.002670e-3
GO:0034383	low-density lipoprotein particle clearance	4.030483e-3
GO:0043408	regulation of MAPKKK cascade	4.078834e-3
GO:0035116	embryonic hindlimb morphogenesis	4.084159e-3
GO:0008216	spermidine metabolic process	4.097778e-3
GO:0046058	cAMP metabolic process	4.117050e-3
GO:0009146	purine nucleoside triphosphate catabolic process	4.125879e-3
GO:0010988	regulation of low-density lipoprotein particle clearance	4.130638e-3
GO:0031665	negative regulation of lipopolysaccharide-mediated signaling pathway	4.169850e-3
GO:0034337	RNA folding	4.195202e-3
GO:0071777	positive regulation of cell cycle cytokinesis	4.257136e-3
GO:0043249	erythrocyte maturation	4.257136e-3
GO:0071305	cellular response to vitamin D	4.261633e-3
GO:0043353	enucleate erythrocyte differentiation	4.315213e-3
GO:0030262	apoptotic nuclear change	4.315912e-3
GO:0001754	eye photoreceptor cell differentiation	4.321100e-3
GO:0009895	negative regulation of catabolic process	4.338240e-3
GO:0032467	positive regulation of cytokinesis	4.395917e-3
GO:0006713	glucocorticoid catabolic process	4.419581e-3
GO:0008652	cellular amino acid biosynthetic process	4.470183e-3
GO:0043163	cell envelope organization	4.480881e-3
GO:0000173	inactivation of MAPK activity involved in osmosensory signaling pathway	4.480881e-3
GO:0021796	cerebral cortex regionalization	4.480881e-3
GO:0030098	lymphocyte differentiation	4.506351e-3
GO:2000380	regulation of mesoderm development	4.525499e-3
GO:0060911	cardiac cell fate commitment	4.525499e-3
GO:0050856	regulation of T cell receptor signaling pathway	4.551460e-3
GO:0070302	regulation of stress-activated protein kinase signaling cascade	4.595279e-3
GO:0021795	cerebral cortex cell migration	4.635947e-3
GO:0051705	behavioral interaction between organisms	4.636241e-3
GO:0010897	negative regulation of triglyceride catabolic process	4.660692e-3
GO:0010987	negative regulation of high-density lipoprotein particle clearance	4.660692e-3
GO:0034381	plasma lipoprotein particle clearance	4.669033e-3
GO:0030878	thyroid gland development	4.669033e-3
GO:0031290	retinal ganglion cell axon guidance	4.692793e-3
GO:0001841	neural tube formation	4.712954e-3
GO:0060769	positive regulation of epithelial cell proliferation involved in prostate gland development	4.723764e-3
GO:0007440	foregut morphogenesis	4.803405e-3
GO:0046483	heterocycle metabolic process	4.829813e-3
GO:0045844	positive regulation of striated muscle tissue development	4.897111e-3
GO:0001502	cartilage condensation	4.913306e-3
GO:0048754	branching morphogenesis of a tube	4.921432e-3
GO:0032785	negative regulation of transcription elongation, DNA-dependent	4.968565e-3
GO:2000660	negative regulation of interleukin-1-mediated signaling pathway	5.005023e-3
GO:0044265	cellular macromolecule catabolic process	5.131855e-3
GO:0051402	neuron apoptosis	5.143268e-3
GO:0060272	embryonic skeletal joint morphogenesis	5.184135e-3
GO:0090307	spindle assembly involved in mitosis	5.201650e-3
GO:0051151	negative regulation of smooth muscle cell differentiation	5.201650e-3
GO:0006346	methylation-dependent chromatin silencing	5.201650e-3
GO:0090183	regulation of kidney development	5.256707e-3
GO:0031664	regulation of lipopolysaccharide-mediated signaling pathway	5.266821e-3
GO:0031999	negative regulation of fatty acid beta-oxidation	5.268055e-3
GO:0000097	sulfur amino acid biosynthetic process	5.295975e-3
GO:0035385	Roundabout signaling pathway	5.297937e-3
GO:0019368	fatty acid elongation, unsaturated fatty acid	5.297937e-3
GO:0043534	blood vessel endothelial cell migration	5.322963e-3
GO:0019605	butyrate metabolic process	5.386378e-3
GO:0001838	embryonic epithelial tube formation	5.402447e-3
GO:0050794	regulation of cellular process	5.405883e-3
GO:0010454	negative regulation of cell fate commitment	5.430518e-3
GO:0043631	RNA polyadenylation	5.438991e-3
GO:0090066	regulation of anatomical structure size	5.499046e-3
GO:0046530	photoreceptor cell differentiation	5.516359e-3
GO:0030816	positive regulation of cAMP metabolic process	5.536636e-3
GO:0030851	granulocyte differentiation	5.561738e-3
GO:0007271	synaptic transmission, cholinergic	5.599337e-3
GO:0060696	regulation of phospholipid catabolic process	5.650152e-3
GO:0007155	cell adhesion	5.655938e-3
GO:0006910	phagocytosis, recognition	5.669422e-3
GO:0001658	branching involved in ureteric bud morphogenesis	5.683363e-3
GO:0009890	negative regulation of biosynthetic process	5.695988e-3
GO:0045892	negative regulation of transcription, DNA-dependent	5.810849e-3
GO:0006139	nucleobase-containing compound metabolic process	5.834099e-3
GO:0060100	positive regulation of phagocytosis, engulfment	5.919734e-3
GO:0008210	estrogen metabolic process	6.069477e-3
GO:0033602	negative regulation of dopamine secretion	6.080971e-3
GO:0030534	adult behavior	6.094272e-3
GO:0042158	lipoprotein biosynthetic process	6.111030e-3
GO:0044281	small molecule metabolic process	6.135642e-3
GO:0034641	cellular nitrogen compound metabolic process	6.199481e-3
GO:0000320	re-entry into mitotic cell cycle	6.249113e-3
GO:0008608	attachment of spindle microtubules to kinetochore	6.249113e-3
GO:0009154	purine ribonucleotide catabolic process	6.294587e-3
GO:0001822	kidney development	6.447267e-3
GO:0010896	regulation of triglyceride catabolic process	6.591138e-3
GO:0051610	serotonin uptake	6.619734e-3
GO:0009268	response to pH	6.722271e-3
GO:0071404	cellular response to low-density lipoprotein particle stimulus	6.726316e-3
GO:0042147	retrograde transport, endosome to Golgi	6.726379e-3
GO:0008211	glucocorticoid metabolic process	6.726379e-3
GO:0048745	smooth muscle tissue development	6.761263e-3
GO:0048671	negative regulation of collateral sprouting	6.771535e-3
GO:0009261	ribonucleotide catabolic process	6.878790e-3
GO:0044060	regulation of endocrine process	6.897478e-3
GO:0051258	protein polymerization	6.912235e-3
GO:0071383	cellular response to steroid hormone stimulus	6.937397e-3
GO:0046328	regulation of JNK cascade	6.957275e-3
GO:0046323	glucose import	7.006877e-3
GO:0045746	negative regulation of Notch signaling pathway	7.023008e-3
GO:0003211	cardiac ventricle formation	7.142229e-3
GO:0006376	mRNA splice site selection	7.148294e-3
GO:0006308	DNA catabolic process	7.157186e-3
GO:0015914	phospholipid transport	7.172598e-3
GO:0051983	regulation of chromosome segregation	7.216615e-3
GO:0006378	mRNA polyadenylation	7.286242e-3
GO:0072175	epithelial tube formation	7.313965e-3
GO:0044029	hypomethylation of CpG island	7.314100e-3
GO:0042699	follicle-stimulating hormone signaling pathway	7.314100e-3
GO:0002118	aggressive behavior	7.314100e-3
GO:0035050	embryonic heart tube development	7.320563e-3
GO:0030219	megakaryocyte differentiation	7.363764e-3
GO:0051046	regulation of secretion	7.367196e-3
GO:0048513	organ development	7.376228e-3
GO:2000113	negative regulation of cellular macromolecule biosynthetic process	7.376343e-3
GO:0014012	peripheral nervous system axon regeneration	7.424900e-3
GO:0031087	deadenylation-independent decapping of nuclear-transcribed mRNA	7.428040e-3
GO:0072215	regulation of metanephros development	7.446353e-3
GO:0045626	negative regulation of T-helper 1 cell differentiation	7.502820e-3
GO:0016080	synaptic vesicle targeting	7.502820e-3
GO:0003084	positive regulation of systemic arterial blood pressure	7.537996e-3
GO:0060675	ureteric bud morphogenesis	7.557978e-3
GO:0048844	artery morphogenesis	7.630253e-3
GO:0008152	metabolic process	7.675516e-3
GO:0001906	cell killing	7.701910e-3

GREAT analysis results for mouseGenomic Enrichment of Annotations Tool (GREAT, Nat Biotechnol. 2010 May;28(5):495-501) is used to identify, both in human and in mouse, the gene ontology terms of biological processes enriched given the predicted TFBSs, and evaluated the overlap in the top-500 gene ontology terms between human and mouse. For each novel motif, the P value for the overlap was then evaluated by calculating its relative rank with respect to this background distribution.<br>Analyst: Michiel de Hoon <br><br>link to source dataset <br>data

---

GO ID	GO Term	p-value
GO:0055090	acylglycerol homeostasis	6.619744e-22
GO:0010902	positive regulation of very-low-density lipoprotein particle remodeling	5.164954e-18
GO:0006982	response to lipid hydroperoxide	3.479371e-17
GO:0002227	innate immune response in mucosa	4.689712e-17
GO:0034370	triglyceride-rich lipoprotein particle remodeling	1.420893e-16
GO:0034372	very-low-density lipoprotein particle remodeling	7.189296e-16
GO:0034445	negative regulation of plasma lipoprotein particle oxidation	2.572523e-15
GO:0034442	regulation of lipoprotein oxidation	5.588786e-15
GO:0070328	triglyceride homeostasis	9.542080e-15
GO:0002385	mucosal immune response	2.325336e-14
GO:0002251	organ or tissue specific immune response	4.388539e-14
GO:2000761	positive regulation of N-terminal peptidyl-lysine acetylation	4.571485e-14
GO:0035910	ascending aorta morphogenesis	4.571485e-14
GO:0050748	negative regulation of lipoprotein metabolic process	4.571485e-14
GO:0042632	cholesterol homeostasis	7.565665e-14
GO:0046464	acylglycerol catabolic process	8.365786e-14
GO:0010901	regulation of very-low-density lipoprotein particle remodeling	1.141773e-13
GO:0046503	glycerolipid catabolic process	2.271311e-13
GO:0019433	triglyceride catabolic process	2.903792e-13
GO:0090208	positive regulation of triglyceride metabolic process	6.595858e-13
GO:0060563	neuroepithelial cell differentiation	8.167913e-13
GO:0042246	tissue regeneration	1.111683e-12
GO:0050996	positive regulation of lipid catabolic process	1.608085e-12
GO:0055088	lipid homeostasis	1.734652e-12
GO:0002328	pro-B cell differentiation	1.993073e-12
GO:0046826	negative regulation of protein export from nucleus	2.348205e-12
GO:0010898	positive regulation of triglyceride catabolic process	2.348205e-12
GO:0042769	DNA damage response, detection of DNA damage	2.436550e-12
GO:0051248	negative regulation of protein metabolic process	2.557781e-12
GO:0003357	noradrenergic neuron differentiation	2.777782e-12
GO:0030300	regulation of intestinal cholesterol absorption	3.163108e-12
GO:0044240	multicellular organismal lipid catabolic process	4.438365e-12
GO:0031099	regeneration	4.871713e-12
GO:0044242	cellular lipid catabolic process	4.996910e-12
GO:0050746	regulation of lipoprotein metabolic process	6.035261e-12
GO:0003289	atrial septum primum morphogenesis	7.019368e-12
GO:0043252	sodium-independent organic anion transport	1.247459e-11
GO:0051006	positive regulation of lipoprotein lipase activity	1.263272e-11
GO:0090201	negative regulation of release of cytochrome c from mitochondria	4.110213e-11
GO:0032269	negative regulation of cellular protein metabolic process	4.751025e-11
GO:0010823	negative regulation of mitochondrion organization	6.713283e-11
GO:0045723	positive regulation of fatty acid biosynthetic process	7.986137e-11
GO:0014009	glial cell proliferation	1.084287e-10
GO:0010896	regulation of triglyceride catabolic process	1.507491e-10
GO:0033194	response to hydroperoxide	1.907327e-10
GO:0043691	reverse cholesterol transport	3.249092e-10
GO:0003183	mitral valve morphogenesis	4.689189e-10
GO:0007159	leukocyte cell-cell adhesion	5.684575e-10
GO:0003211	cardiac ventricle formation	6.135900e-10
GO:0006977	DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest	9.801771e-10
GO:0003207	cardiac chamber formation	9.843747e-10
GO:0072404	signal transduction involved in G1/S transition checkpoint	1.295947e-9
GO:0060413	atrial septum morphogenesis	1.327077e-9
GO:0019827	stem cell maintenance	1.564483e-9
GO:2000758	positive regulation of peptidyl-lysine acetylation	1.662689e-9
GO:0072422	signal transduction involved in DNA damage checkpoint	1.783657e-9
GO:0072395	signal transduction involved in cell cycle checkpoint	2.123292e-9
GO:0045919	positive regulation of cytolysis	2.485846e-9
GO:0031400	negative regulation of protein modification process	2.737088e-9
GO:0042157	lipoprotein metabolic process	2.818427e-9
GO:0010873	positive regulation of cholesterol esterification	2.921241e-9
GO:0048864	stem cell development	3.599626e-9
GO:0065005	protein-lipid complex assembly	3.692186e-9
GO:0090207	regulation of triglyceride metabolic process	4.364385e-9
GO:0044243	multicellular organismal catabolic process	4.543636e-9
GO:0046825	regulation of protein export from nucleus	5.012771e-9
GO:0031647	regulation of protein stability	5.277924e-9
GO:0044058	regulation of digestive system process	5.404868e-9
GO:2000756	regulation of peptidyl-lysine acetylation	5.756019e-9
GO:0035634	response to stilbenoid	6.490205e-9
GO:0034369	plasma lipoprotein particle remodeling	7.332133e-9
GO:0032232	negative regulation of actin filament bundle assembly	8.000247e-9
GO:0035904	aorta development	8.468345e-9
GO:0010872	regulation of cholesterol esterification	1.202973e-8
GO:0033700	phospholipid efflux	1.290539e-8
GO:0070373	negative regulation of ERK1 and ERK2 cascade	1.383933e-8
GO:0032368	regulation of lipid transport	1.795418e-8
GO:0060739	mesenchymal-epithelial cell signaling involved in prostate gland development	1.953034e-8
GO:0003283	atrial septum development	2.433805e-8
GO:0035909	aorta morphogenesis	2.725595e-8
GO:0044241	lipid digestion	3.312008e-8
GO:0031018	endocrine pancreas development	3.322609e-8
GO:0016042	lipid catabolic process	4.332460e-8
GO:0048878	chemical homeostasis	4.579427e-8
GO:0060191	regulation of lipase activity	4.882895e-8
GO:0031397	negative regulation of protein ubiquitination	4.942369e-8
GO:0002320	lymphoid progenitor cell differentiation	5.359819e-8
GO:0051004	regulation of lipoprotein lipase activity	6.162322e-8
GO:0090199	regulation of release of cytochrome c from mitochondria	9.153616e-8
GO:0035019	somatic stem cell maintenance	1.040106e-7
GO:0031016	pancreas development	1.315943e-7
GO:0042744	hydrogen peroxide catabolic process	1.496631e-7
GO:0060174	limb bud formation	1.572600e-7
GO:0019430	removal of superoxide radicals	1.680436e-7
GO:0021764	amygdala development	1.939482e-7
GO:0050994	regulation of lipid catabolic process	2.244517e-7
GO:0050821	protein stabilization	2.370828e-7
GO:0003215	cardiac right ventricle morphogenesis	2.569425e-7
GO:0008202	steroid metabolic process	2.622525e-7
GO:0071827	plasma lipoprotein particle organization	2.647000e-7
GO:0006641	triglyceride metabolic process	2.772657e-7
GO:0060412	ventricular septum morphogenesis	3.517870e-7
GO:0010519	negative regulation of phospholipase activity	4.025491e-7
GO:0031571	mitotic cell cycle G1/S transition DNA damage checkpoint	4.059037e-7
GO:0071333	cellular response to glucose stimulus	4.073971e-7
GO:0006638	neutral lipid metabolic process	4.283190e-7
GO:0097006	regulation of plasma lipoprotein particle levels	5.095660e-7
GO:0030098	lymphocyte differentiation	5.491854e-7
GO:0006639	acylglycerol metabolic process	6.057765e-7
GO:0042770	signal transduction in response to DNA damage	6.459230e-7
GO:0045923	positive regulation of fatty acid metabolic process	7.396489e-7
GO:0031100	organ regeneration	7.902747e-7
GO:0008203	cholesterol metabolic process	8.359306e-7
GO:0002521	leukocyte differentiation	8.616652e-7
GO:0042743	hydrogen peroxide metabolic process	1.092107e-6
GO:0001678	cellular glucose homeostasis	1.142197e-6
GO:0000303	response to superoxide	1.142417e-6
GO:0016125	sterol metabolic process	1.173198e-6
GO:0006801	superoxide metabolic process	1.305251e-6
GO:0070842	aggresome assembly	1.326733e-6
GO:0010821	regulation of mitochondrion organization	1.344304e-6
GO:0009896	positive regulation of catabolic process	1.391151e-6
GO:0006396	RNA processing	1.579200e-6
GO:0002244	hemopoietic progenitor cell differentiation	1.764723e-6
GO:0021517	ventral spinal cord development	2.391739e-6
GO:0032374	regulation of cholesterol transport	2.484260e-6
GO:0042304	regulation of fatty acid biosynthetic process	2.631511e-6
GO:0060840	artery development	2.800956e-6
GO:0048863	stem cell differentiation	2.834990e-6
GO:0000305	response to oxygen radical	3.069585e-6
GO:0071779	G1/S transition checkpoint	3.180052e-6
GO:0060193	positive regulation of lipase activity	3.263171e-6
GO:0071322	cellular response to carbohydrate stimulus	3.311803e-6
GO:0042221	response to chemical stimulus	3.459223e-6
GO:0031427	response to methotrexate	3.524803e-6
GO:0045834	positive regulation of lipid metabolic process	3.534946e-6
GO:0090317	negative regulation of intracellular protein transport	3.683954e-6
GO:0033539	fatty acid beta-oxidation using acyl-CoA dehydrogenase	3.780977e-6
GO:0006353	transcription termination, DNA-dependent	3.780977e-6
GO:0001788	antibody-dependent cellular cytotoxicity	4.356878e-6
GO:0003179	heart valve morphogenesis	4.396380e-6
GO:0031331	positive regulation of cellular catabolic process	4.498113e-6
GO:0030330	DNA damage response, signal transduction by p53 class mediator	4.563377e-6
GO:0009894	regulation of catabolic process	5.063392e-6
GO:0033344	cholesterol efflux	5.194477e-6
GO:0048844	artery morphogenesis	5.205712e-6
GO:0042592	homeostatic process	5.440040e-6
GO:0071158	positive regulation of cell cycle arrest	5.462385e-6
GO:0032387	negative regulation of intracellular transport	5.491881e-6
GO:0048485	sympathetic nervous system development	5.535858e-6
GO:0046470	phosphatidylcholine metabolic process	5.535858e-6
GO:0031508	centromeric heterochromatin formation	5.956483e-6
GO:0060411	cardiac septum morphogenesis	6.105466e-6
GO:0046823	negative regulation of nucleocytoplasmic transport	6.134695e-6
GO:0042843	D-xylose catabolic process	6.389316e-6
GO:0003170	heart valve development	6.578012e-6
GO:0016567	protein ubiquitination	6.671598e-6
GO:0014067	negative regulation of phosphatidylinositol 3-kinase cascade	6.726085e-6
GO:0046889	positive regulation of lipid biosynthetic process	6.853048e-6
GO:0031575	mitotic cell cycle G1/S transition checkpoint	6.875284e-6
GO:0021522	spinal cord motor neuron differentiation	7.770447e-6
GO:0014904	myotube cell development	8.047872e-6
GO:0001810	regulation of type I hypersensitivity	8.047872e-6
GO:0000422	mitochondrion degradation	8.047872e-6
GO:0006662	glycerol ether metabolic process	8.448261e-6
GO:0045321	leukocyte activation	1.018119e-5
GO:0045023	G0 to G1 transition	1.051956e-5
GO:0046649	lymphocyte activation	1.084619e-5
GO:0051583	dopamine uptake	1.163713e-5
GO:0042268	regulation of cytolysis	1.163713e-5
GO:0000289	nuclear-transcribed mRNA poly(A) tail shortening	1.176214e-5
GO:0030263	apoptotic chromosome condensation	1.361827e-5
GO:0072331	signal transduction by p53 class mediator	1.393724e-5
GO:0042439	ethanolamine-containing compound metabolic process	1.410731e-5
GO:0006110	regulation of glycolysis	1.543026e-5
GO:0072593	reactive oxygen species metabolic process	1.594228e-5
GO:0001933	negative regulation of protein phosphorylation	1.659322e-5
GO:0002526	acute inflammatory response	1.677950e-5
GO:0033554	cellular response to stress	1.733902e-5
GO:0009992	cellular water homeostasis	1.740161e-5
GO:0050851	antigen receptor-mediated signaling pathway	1.817515e-5
GO:0006629	lipid metabolic process	1.942900e-5
GO:0010216	maintenance of DNA methylation	2.030766e-5
GO:0007093	mitotic cell cycle checkpoint	2.307626e-5
GO:0002891	positive regulation of immunoglobulin mediated immune response	2.469491e-5
GO:0051224	negative regulation of protein transport	2.565358e-5
GO:0045821	positive regulation of glycolysis	2.623762e-5
GO:0014896	muscle hypertrophy	2.765171e-5
GO:0042100	B cell proliferation	2.822694e-5
GO:0030217	T cell differentiation	3.064255e-5
GO:0060741	prostate gland stromal morphogenesis	3.072012e-5
GO:0006397	mRNA processing	3.188797e-5
GO:0001510	RNA methylation	3.300555e-5
GO:0045079	negative regulation of chemokine biosynthetic process	3.379915e-5
GO:0001812	positive regulation of type I hypersensitivity	3.379915e-5
GO:0001777	T cell homeostatic proliferation	3.452903e-5
GO:0031329	regulation of cellular catabolic process	3.536490e-5
GO:0035630	bone mineralization involved in bone maturation	3.552205e-5
GO:0030301	cholesterol transport	3.563764e-5
GO:0032446	protein modification by small protein conjugation	3.651671e-5
GO:0051128	regulation of cellular component organization	3.667995e-5
GO:0045936	negative regulation of phosphate metabolic process	4.122379e-5
GO:0051088	PMA-inducible membrane protein ectodomain proteolysis	4.132015e-5
GO:0030104	water homeostasis	4.172293e-5
GO:0045940	positive regulation of steroid metabolic process	4.271817e-5
GO:0002429	immune response-activating cell surface receptor signaling pathway	4.345360e-5
GO:0003281	ventricular septum development	4.370612e-5
GO:0015914	phospholipid transport	4.605809e-5
GO:0042113	B cell activation	4.607036e-5
GO:0008033	tRNA processing	4.709559e-5
GO:0018904	organic ether metabolic process	4.868485e-5
GO:0015844	monoamine transport	4.975405e-5
GO:0042326	negative regulation of phosphorylation	5.259114e-5
GO:0010506	regulation of autophagy	5.636650e-5
GO:0006576	cellular biogenic amine metabolic process	5.715654e-5
GO:0030488	tRNA methylation	5.795591e-5
GO:0006379	mRNA cleavage	6.103908e-5
GO:0034470	ncRNA processing	6.135120e-5
GO:0045725	positive regulation of glycogen biosynthetic process	6.248032e-5
GO:0050853	B cell receptor signaling pathway	6.748793e-5
GO:0002768	immune response-regulating cell surface receptor signaling pathway	6.798365e-5
GO:0042060	wound healing	7.033922e-5
GO:0001844	protein insertion into mitochondrial membrane involved in induction of apoptosis	7.181890e-5
GO:0014012	peripheral nervous system axon regeneration	7.588501e-5
GO:0072368	regulation of lipid transport by negative regulation of transcription from RNA polymerase II promoter	8.473731e-5
GO:0072362	regulation of glycolysis by negative regulation of transcription from RNA polymerase II promoter	8.473731e-5
GO:0043931	ossification involved in bone maturation	8.853070e-5
GO:0070301	cellular response to hydrogen peroxide	9.554100e-5
GO:0044236	multicellular organismal metabolic process	9.641934e-5
GO:0003279	cardiac septum development	9.925232e-5
GO:0031055	chromatin remodeling at centromere	1.001916e-4
GO:0043552	positive regulation of phosphatidylinositol 3-kinase activity	1.010673e-4
GO:0014066	regulation of phosphatidylinositol 3-kinase cascade	1.011667e-4
GO:0000209	protein polyubiquitination	1.022905e-4
GO:0051606	detection of stimulus	1.062237e-4
GO:0030264	nuclear fragmentation involved in apoptotic nuclear change	1.094698e-4
GO:0032879	regulation of localization	1.101368e-4
GO:0050789	regulation of biological process	1.110500e-4
GO:0009725	response to hormone stimulus	1.112563e-4
GO:0001915	negative regulation of T cell mediated cytotoxicity	1.141981e-4
GO:0010605	negative regulation of macromolecule metabolic process	1.147189e-4
GO:0001805	positive regulation of type III hypersensitivity	1.172553e-4
GO:0032853	positive regulation of Ran GTPase activity	1.183703e-4
GO:0051246	regulation of protein metabolic process	1.199106e-4
GO:0031396	regulation of protein ubiquitination	1.220844e-4
GO:0010608	posttranscriptional regulation of gene expression	1.259778e-4
GO:0001775	cell activation	1.281768e-4
GO:0043407	negative regulation of MAP kinase activity	1.310684e-4
GO:0050852	T cell receptor signaling pathway	1.312317e-4
GO:2000045	regulation of G1/S transition of mitotic cell cycle	1.354029e-4
GO:0009749	response to glucose stimulus	1.360080e-4
GO:0030183	B cell differentiation	1.382853e-4
GO:0035520	monoubiquitinated protein deubiquitination	1.390450e-4
GO:0070977	bone maturation	1.394579e-4
GO:0090218	positive regulation of lipid kinase activity	1.402959e-4
GO:0008206	bile acid metabolic process	1.518713e-4
GO:0043568	positive regulation of insulin-like growth factor receptor signaling pathway	1.525117e-4
GO:0003208	cardiac ventricle morphogenesis	1.571091e-4
GO:0051204	protein insertion into mitochondrial membrane	1.579812e-4
GO:0006808	regulation of nitrogen utilization	1.579812e-4
GO:0002757	immune response-activating signal transduction	1.607812e-4
GO:0010676	positive regulation of cellular carbohydrate metabolic process	1.699215e-4
GO:0042063	gliogenesis	1.700148e-4
GO:0045727	positive regulation of translation	1.714173e-4
GO:0034113	heterotypic cell-cell adhesion	1.779650e-4
GO:0034349	glial cell apoptosis	1.799770e-4
GO:0009743	response to carbohydrate stimulus	1.844090e-4
GO:0042417	dopamine metabolic process	1.897852e-4
GO:0021515	cell differentiation in spinal cord	1.943513e-4
GO:0051497	negative regulation of stress fiber assembly	1.951345e-4
GO:0032024	positive regulation of insulin secretion	1.956402e-4
GO:0002710	negative regulation of T cell mediated immunity	2.015761e-4
GO:0070936	protein K48-linked ubiquitination	2.106523e-4
GO:0014834	satellite cell maintenance involved in skeletal muscle regeneration	2.111966e-4
GO:0031401	positive regulation of protein modification process	2.138948e-4
GO:0060452	positive regulation of cardiac muscle contraction	2.148669e-4
GO:0048483	autonomic nervous system development	2.189987e-4
GO:0044255	cellular lipid metabolic process	2.270175e-4
GO:0045446	endothelial cell differentiation	2.302256e-4
GO:0003209	cardiac atrium morphogenesis	2.325877e-4
GO:0006661	phosphatidylinositol biosynthetic process	2.345556e-4
GO:0006921	cellular component disassembly involved in apoptosis	2.345556e-4
GO:0070875	positive regulation of glycogen metabolic process	2.370769e-4
GO:0006950	response to stress	2.503556e-4
GO:0002352	B cell negative selection	2.622195e-4
GO:0051049	regulation of transport	2.675640e-4
GO:0006370	mRNA capping	2.709644e-4
GO:0002764	immune response-regulating signaling pathway	2.804854e-4
GO:0060766	negative regulation of androgen receptor signaling pathway	2.808127e-4
GO:0055082	cellular chemical homeostasis	2.974534e-4
GO:0002925	positive regulation of humoral immune response mediated by circulating immunoglobulin	3.049985e-4
GO:0006690	icosanoid metabolic process	3.076412e-4
GO:0060318	definitive erythrocyte differentiation	3.092475e-4
GO:0090049	regulation of cell migration involved in sprouting angiogenesis	3.092475e-4
GO:0003009	skeletal muscle contraction	3.215897e-4
GO:0042110	T cell activation	3.239841e-4
GO:0071156	regulation of cell cycle arrest	3.268869e-4
GO:0051873	killing by host of symbiont cells	3.385843e-4
GO:0009746	response to hexose stimulus	3.400636e-4
GO:0016337	cell-cell adhesion	3.530393e-4
GO:0002438	acute inflammatory response to antigenic stimulus	3.572290e-4
GO:0050855	regulation of B cell receptor signaling pathway	3.586029e-4
GO:0009892	negative regulation of metabolic process	3.608550e-4
GO:0009719	response to endogenous stimulus	3.622033e-4
GO:0070647	protein modification by small protein conjugation or removal	3.641131e-4
GO:0043086	negative regulation of catalytic activity	3.662766e-4
GO:0034392	negative regulation of smooth muscle cell apoptosis	3.700545e-4
GO:0043471	regulation of cellular carbohydrate catabolic process	3.723171e-4
GO:0001909	leukocyte mediated cytotoxicity	3.758936e-4
GO:0006680	glucosylceramide catabolic process	3.786588e-4
GO:0046486	glycerolipid metabolic process	3.845386e-4
GO:0042628	mating plug formation	3.895539e-4
GO:0003158	endothelium development	3.967192e-4
GO:0030262	apoptotic nuclear change	4.172074e-4
GO:0006974	response to DNA damage stimulus	4.204829e-4
GO:0006650	glycerophospholipid metabolic process	4.321489e-4
GO:0060564	negative regulation of mitotic anaphase-promoting complex activity	4.489138e-4
GO:0035625	epidermal growth factor-activated receptor transactivation by G-protein coupled receptor signaling pathway	4.489138e-4
GO:0051726	regulation of cell cycle	4.517239e-4
GO:0048661	positive regulation of smooth muscle cell proliferation	4.602426e-4
GO:0031047	gene silencing by RNA	4.638990e-4
GO:0010907	positive regulation of glucose metabolic process	4.716418e-4
GO:0001906	cell killing	4.736683e-4
GO:0003230	cardiac atrium development	5.174980e-4
GO:0046666	retinal cell programmed cell death	5.279833e-4
GO:0002358	B cell homeostatic proliferation	5.279833e-4
GO:0002923	regulation of humoral immune response mediated by circulating immunoglobulin	5.339360e-4
GO:0000075	cell cycle checkpoint	5.361417e-4
GO:0000956	nuclear-transcribed mRNA catabolic process	5.488451e-4
GO:0002467	germinal center formation	5.571883e-4
GO:0060426	lung vasculature development	5.668305e-4
GO:0010639	negative regulation of organelle organization	5.814395e-4
GO:0034284	response to monosaccharide stimulus	5.853808e-4
GO:0032787	monocarboxylic acid metabolic process	5.854343e-4
GO:0021510	spinal cord development	5.893898e-4
GO:0060509	Type I pneumocyte differentiation	6.126720e-4
GO:0070947	neutrophil mediated killing of fungus	6.164675e-4
GO:0035914	skeletal muscle cell differentiation	6.190007e-4
GO:0090277	positive regulation of peptide hormone secretion	6.286448e-4
GO:0002823	negative regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains	6.336871e-4
GO:0007155	cell adhesion	6.389259e-4
GO:0044265	cellular macromolecule catabolic process	6.491249e-4
GO:0034660	ncRNA metabolic process	6.514235e-4
GO:0015872	dopamine transport	6.527912e-4
GO:0060164	regulation of timing of neuron differentiation	6.527912e-4
GO:0006497	protein lipidation	6.633529e-4
GO:0048678	response to axon injury	6.636384e-4
GO:0002118	aggressive behavior	6.691432e-4
GO:0008052	sensory organ boundary specification	6.902366e-4
GO:0007402	ganglion mother cell fate determination	6.902366e-4
GO:0010747	positive regulation of plasma membrane long-chain fatty acid transport	7.027088e-4
GO:0019217	regulation of fatty acid metabolic process	7.093237e-4
GO:0030097	hemopoiesis	7.107422e-4
GO:0048597	post-embryonic camera-type eye morphogenesis	7.149708e-4
GO:0042732	D-xylose metabolic process	7.149708e-4
GO:0009887	organ morphogenesis	7.342729e-4
GO:0021819	layer formation in cerebral cortex	7.394609e-4
GO:0005979	regulation of glycogen biosynthetic process	7.438727e-4
GO:0022610	biological adhesion	7.486863e-4
GO:0043409	negative regulation of MAPKKK cascade	7.549298e-4
GO:0016071	mRNA metabolic process	7.689693e-4
GO:0070997	neuron death	7.699947e-4
GO:0002793	positive regulation of peptide secretion	7.741316e-4
GO:0032231	regulation of actin filament bundle assembly	7.993426e-4
GO:0009452	RNA capping	8.151504e-4
GO:0051436	negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle	8.241005e-4
GO:0002889	regulation of immunoglobulin mediated immune response	8.382526e-4
GO:0001516	prostaglandin biosynthetic process	8.451304e-4
GO:0006953	acute-phase response	8.550946e-4
GO:0048015	phosphatidylinositol-mediated signaling	8.550946e-4
GO:0010033	response to organic substance	8.614190e-4
GO:0001662	behavioral fear response	8.956333e-4
GO:0034508	centromere complex assembly	8.964647e-4
GO:0045657	positive regulation of monocyte differentiation	8.964647e-4
GO:0001963	synaptic transmission, dopaminergic	9.392711e-4
GO:0002209	behavioral defense response	9.507012e-4
GO:0009611	response to wounding	9.606985e-4
GO:0043467	regulation of generation of precursor metabolites and energy	9.689896e-4
GO:0009893	positive regulation of metabolic process	9.915237e-4
GO:0048583	regulation of response to stimulus	1.010822e-3
GO:0051247	positive regulation of protein metabolic process	1.033840e-3
GO:0044092	negative regulation of molecular function	1.053432e-3
GO:0070943	neutrophil mediated killing of symbiont cell	1.076676e-3
GO:0046340	diacylglycerol catabolic process	1.076676e-3
GO:0019987	negative regulation of anti-apoptosis	1.076995e-3
GO:0002820	negative regulation of adaptive immune response	1.084524e-3
GO:0043567	regulation of insulin-like growth factor receptor signaling pathway	1.084524e-3
GO:0051593	response to folic acid	1.099414e-3
GO:0001504	neurotransmitter uptake	1.104522e-3
GO:0031324	negative regulation of cellular metabolic process	1.111314e-3
GO:0051482	elevation of cytosolic calcium ion concentration involved in G-protein signaling coupled to IP3 second messenger	1.115443e-3
GO:0006417	regulation of translation	1.119828e-3
GO:0007194	negative regulation of adenylate cyclase activity	1.122148e-3
GO:0006693	prostaglandin metabolic process	1.141430e-3
GO:0010741	negative regulation of intracellular protein kinase cascade	1.167794e-3
GO:0051896	regulation of protein kinase B signaling cascade	1.171042e-3
GO:0090068	positive regulation of cell cycle process	1.172020e-3
GO:0006346	methylation-dependent chromatin silencing	1.176733e-3
GO:0043551	regulation of phosphatidylinositol 3-kinase activity	1.184747e-3
GO:0021953	central nervous system neuron differentiation	1.222512e-3
GO:0006401	RNA catabolic process	1.229587e-3
GO:0006402	mRNA catabolic process	1.236642e-3
GO:0070979	protein K11-linked ubiquitination	1.240590e-3
GO:0046512	sphingosine biosynthetic process	1.283139e-3
GO:0060192	negative regulation of lipase activity	1.333741e-3
GO:0042158	lipoprotein biosynthetic process	1.360528e-3
GO:0045059	positive thymic T cell selection	1.371132e-3
GO:0055099	response to high density lipoprotein particle stimulus	1.379066e-3
GO:0000077	DNA damage checkpoint	1.382471e-3
GO:0034614	cellular response to reactive oxygen species	1.401016e-3
GO:0051937	catecholamine transport	1.402104e-3
GO:0045830	positive regulation of isotype switching	1.421916e-3
GO:0050794	regulation of cellular process	1.460804e-3
GO:0010517	regulation of phospholipase activity	1.516279e-3
GO:0042590	antigen processing and presentation of exogenous peptide antigen via MHC class I	1.517025e-3
GO:0032878	regulation of establishment or maintenance of cell polarity	1.529988e-3
GO:0002361	CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation	1.550460e-3
GO:0008284	positive regulation of cell proliferation	1.627960e-3
GO:0021987	cerebral cortex development	1.668278e-3
GO:0001101	response to acid	1.704412e-3
GO:0072659	protein localization in plasma membrane	1.713459e-3
GO:0021960	anterior commissure morphogenesis	1.734364e-3
GO:0002175	protein localization to paranode region of axon	1.736124e-3
GO:0033135	regulation of peptidyl-serine phosphorylation	1.749011e-3
GO:0031570	DNA integrity checkpoint	1.780856e-3
GO:0007015	actin filament organization	1.817710e-3
GO:0070873	regulation of glycogen metabolic process	1.869059e-3
GO:0019218	regulation of steroid metabolic process	1.869735e-3
GO:0032717	negative regulation of interleukin-8 production	1.936656e-3
GO:0009123	nucleoside monophosphate metabolic process	1.938111e-3
GO:0051129	negative regulation of cellular component organization	1.954318e-3
GO:0090073	positive regulation of protein homodimerization activity	1.958793e-3
GO:0044248	cellular catabolic process	1.973269e-3
GO:0060740	prostate gland epithelium morphogenesis	1.980552e-3
GO:0050732	negative regulation of peptidyl-tyrosine phosphorylation	2.042894e-3
GO:0031103	axon regeneration	2.042894e-3
GO:0048304	positive regulation of isotype switching to IgG isotypes	2.074074e-3
GO:0065007	biological regulation	2.092130e-3
GO:0045070	positive regulation of viral genome replication	2.093212e-3
GO:0031017	exocrine pancreas development	2.100901e-3
GO:0002376	immune system process	2.101145e-3
GO:0060512	prostate gland morphogenesis	2.113880e-3
GO:0032386	regulation of intracellular transport	2.117391e-3
GO:0019725	cellular homeostasis	2.171309e-3
GO:0031123	RNA 3'-end processing	2.199612e-3
GO:0045911	positive regulation of DNA recombination	2.223036e-3
GO:0002524	hypersensitivity	2.237398e-3
GO:0046887	positive regulation of hormone secretion	2.238406e-3
GO:0009057	macromolecule catabolic process	2.295773e-3
GO:0060765	regulation of androgen receptor signaling pathway	2.349728e-3
GO:0010001	glial cell differentiation	2.360008e-3
GO:0045588	positive regulation of gamma-delta T cell differentiation	2.389952e-3
GO:0001820	serotonin secretion	2.406935e-3
GO:0048505	regulation of timing of cell differentiation	2.447722e-3
GO:0007008	outer mitochondrial membrane organization	2.472739e-3
GO:0065008	regulation of biological quality	2.489853e-3
GO:0010675	regulation of cellular carbohydrate metabolic process	2.534765e-3
GO:0030279	negative regulation of ossification	2.542606e-3
GO:0032268	regulation of cellular protein metabolic process	2.545288e-3
GO:0006631	fatty acid metabolic process	2.561231e-3
GO:0001974	blood vessel remodeling	2.589905e-3
GO:0006446	regulation of translational initiation	2.604027e-3
GO:0050896	response to stimulus	2.610394e-3
GO:0010876	lipid localization	2.629689e-3
GO:0023021	termination of signal transduction	2.633367e-3
GO:0071205	protein localization to juxtaparanode region of axon	2.633367e-3
GO:0042596	fear response	2.669698e-3
GO:0045844	positive regulation of striated muscle tissue development	2.721049e-3
GO:0003231	cardiac ventricle development	2.778636e-3
GO:0006109	regulation of carbohydrate metabolic process	2.784768e-3
GO:0050655	dermatan sulfate proteoglycan metabolic process	2.858182e-3
GO:0070534	protein K63-linked ubiquitination	2.873887e-3
GO:0046626	regulation of insulin receptor signaling pathway	2.894159e-3
GO:0046477	glycosylceramide catabolic process	2.899246e-3
GO:0060527	prostate epithelial cord arborization involved in prostate glandular acinus morphogenesis	2.910667e-3
GO:0007007	inner mitochondrial membrane organization	2.910667e-3
GO:0048311	mitochondrion distribution	2.971484e-3
GO:0007193	inhibition of adenylate cyclase activity by G-protein signaling pathway	3.057443e-3
GO:0040034	regulation of development, heterochronic	3.104695e-3
GO:0033025	regulation of mast cell apoptosis	3.182898e-3
GO:0014902	myotube differentiation	3.202096e-3
GO:0050857	positive regulation of antigen receptor-mediated signaling pathway	3.226354e-3
GO:0046456	icosanoid biosynthetic process	3.245316e-3
GO:0043255	regulation of carbohydrate biosynthetic process	3.275555e-3
GO:0030032	lamellipodium assembly	3.311355e-3
GO:0072661	protein targeting to plasma membrane	3.324650e-3
GO:2001108	positive regulation of Rho guanyl-nucleotide exchange factor activity	3.347365e-3
GO:0034126	positive regulation of MyD88-dependent toll-like receptor signaling pathway	3.347365e-3
GO:2000727	positive regulation of cardiac muscle cell differentiation	3.351682e-3
GO:0051387	negative regulation of nerve growth factor receptor signaling pathway	3.397263e-3
GO:0033627	cell adhesion mediated by integrin	3.397263e-3
GO:0032922	circadian regulation of gene expression	3.397263e-3
GO:0021801	cerebral cortex radial glia guided migration	3.425324e-3
GO:0048534	hemopoietic or lymphoid organ development	3.431626e-3
GO:0030511	positive regulation of transforming growth factor beta receptor signaling pathway	3.455247e-3
GO:0033144	negative regulation of steroid hormone receptor signaling pathway	3.480751e-3
GO:0006399	tRNA metabolic process	3.543657e-3
GO:0044238	primary metabolic process	3.544793e-3
GO:0035024	negative regulation of Rho protein signal transduction	3.629888e-3
GO:0051017	actin filament bundle assembly	3.659304e-3