Novel motif:3

name:	motif3_CGCTNA

Association to promoter expression in human samples<b>Summary:</b>Significance of the correlation with CAGE expression, human <br><b>Analyst:</b> Michiel de Hoon<br><br>link to source dataset <br>data

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Association to promoter expression in mouse samples <b>Summary:</b>Significance of the correlation with CAGE expression, mouse <br><b>Analyst:</b> Michiel de Hoon<br><br>link to source dataset <br>data

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GREAT analysis results for human <b>Summary:</b>Genomic Enrichment of Annotations Tool (GREAT, Nat Biotechnol. 2010 May;28(5):495-501) is used to identify, both in human and in mouse, the gene ontology terms of biological processes enriched given the predicted TFBSs, and evaluated the overlap in the top-500 gene ontology terms between human and mouse. For each novel motif, the P value for the overlap was then evaluated by calculating its relative rank with respect to this background distribution.<br>Analyst: Michiel de Hoon<br><br>link to source dataset <br>data

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GO ID	GO Term	p-value
GO:0002679	respiratory burst involved in defense response	1.679784e-9
GO:0043503	skeletal muscle fiber adaptation	2.177060e-9
GO:0006481	C-terminal protein methylation	1.554846e-8
GO:0002149	hypochlorous acid biosynthetic process	1.565026e-8
GO:0042503	tyrosine phosphorylation of Stat3 protein	1.780977e-8
GO:0000387	spliceosomal snRNP assembly	1.935285e-8
GO:0021987	cerebral cortex development	3.152629e-8
GO:0021986	habenula development	1.897553e-7
GO:0000226	microtubule cytoskeleton organization	2.927338e-7
GO:0040001	establishment of mitotic spindle localization	3.398831e-7
GO:0042506	tyrosine phosphorylation of Stat5 protein	4.538972e-7
GO:0061014	positive regulation of mRNA catabolic process	5.106888e-7
GO:0042508	tyrosine phosphorylation of Stat1 protein	6.890130e-7
GO:0001522	pseudouridine synthesis	8.302580e-7
GO:0000389	nuclear mRNA 3'-splice site recognition	1.018343e-6
GO:0000296	spermine transport	1.155152e-6
GO:0034660	ncRNA metabolic process	1.200351e-6
GO:0022613	ribonucleoprotein complex biogenesis	1.600170e-6
GO:0051298	centrosome duplication	1.685513e-6
GO:0051297	centrosome organization	1.724492e-6
GO:0021877	forebrain neuron fate commitment	1.942121e-6
GO:0003310	pancreatic A cell differentiation	1.971669e-6
GO:0050685	positive regulation of mRNA processing	2.486338e-6
GO:0006396	RNA processing	2.487588e-6
GO:0006261	DNA-dependent DNA replication	3.496116e-6
GO:0061013	regulation of mRNA catabolic process	3.497497e-6
GO:0019264	glycine biosynthetic process from serine	3.688892e-6
GO:0030421	defecation	4.270526e-6
GO:0021903	rostrocaudal neural tube patterning	4.393452e-6
GO:0043501	skeletal muscle adaptation	4.830428e-6
GO:0000132	establishment of mitotic spindle orientation	4.952933e-6
GO:0000089	mitotic metaphase	5.150502e-6
GO:0003148	outflow tract septum morphogenesis	6.117573e-6
GO:0006600	creatine metabolic process	7.025104e-6
GO:0035966	response to topologically incorrect protein	7.372758e-6
GO:0031023	microtubule organizing center organization	7.852303e-6
GO:0070544	histone H3-K36 demethylation	7.952424e-6
GO:0090086	negative regulation of protein deubiquitination	8.919890e-6
GO:0006285	base-excision repair, AP site formation	9.863114e-6
GO:0048488	synaptic vesicle endocytosis	1.041264e-5
GO:0043517	positive regulation of DNA damage response, signal transduction by p53 class mediator	1.078888e-5
GO:0071843	cellular component biogenesis at cellular level	1.130801e-5
GO:0051549	positive regulation of keratinocyte migration	1.241959e-5
GO:0051890	regulation of cardioblast differentiation	1.276925e-5
GO:0042416	dopamine biosynthetic process	1.299891e-5
GO:0000966	RNA 5'-end processing	1.365332e-5
GO:0006986	response to unfolded protein	1.422663e-5
GO:0034470	ncRNA processing	1.475083e-5
GO:0021892	cerebral cortex GABAergic interneuron differentiation	1.477122e-5
GO:0032042	mitochondrial DNA metabolic process	1.685268e-5
GO:0051891	positive regulation of cardioblast differentiation	1.752726e-5
GO:0051293	establishment of spindle localization	1.769470e-5
GO:0035305	negative regulation of dephosphorylation	1.942764e-5
GO:0006353	transcription termination, DNA-dependent	2.242886e-5
GO:0019430	removal of superoxide radicals	2.472176e-5
GO:0010994	free ubiquitin chain polymerization	2.633216e-5
GO:0045007	depurination	2.633216e-5
GO:0008033	tRNA processing	2.703776e-5
GO:0006545	glycine biosynthetic process	2.729450e-5
GO:0021543	pallium development	2.745234e-5
GO:0052697	xenobiotic glucuronidation	2.967403e-5
GO:0070980	biphenyl catabolic process	2.967403e-5
GO:0052696	flavonoid glucuronidation	2.967403e-5
GO:0051552	flavone metabolic process	2.967403e-5
GO:0006789	bilirubin conjugation	2.967403e-5
GO:0006399	tRNA metabolic process	3.176754e-5
GO:0051303	establishment of chromosome localization	3.501884e-5
GO:0031442	positive regulation of mRNA 3'-end processing	3.503832e-5
GO:0043587	tongue morphogenesis	3.680307e-5
GO:2001022	positive regulation of response to DNA damage stimulus	3.852921e-5
GO:0090084	negative regulation of inclusion body assembly	3.886650e-5
GO:0051488	activation of anaphase-promoting complex activity	3.886650e-5
GO:0090245	axis elongation involved in somitogenesis	3.918213e-5
GO:0021874	Wnt receptor signaling pathway involved in forebrain neuroblast division	3.918213e-5
GO:0060236	regulation of mitotic spindle organization	4.620999e-5
GO:0007098	centrosome cycle	4.725751e-5
GO:0000083	regulation of transcription involved in G1/S phase of mitotic cell cycle	4.822992e-5
GO:0022618	ribonucleoprotein complex assembly	4.915066e-5
GO:0007260	tyrosine phosphorylation of STAT protein	5.034635e-5
GO:0000086	G2/M transition of mitotic cell cycle	5.047717e-5
GO:0032926	negative regulation of activin receptor signaling pathway	5.064624e-5
GO:0045835	negative regulation of meiosis	5.090123e-5
GO:0030327	prenylated protein catabolic process	5.469655e-5
GO:0006369	termination of RNA polymerase II transcription	5.588043e-5
GO:0071826	ribonucleoprotein complex subunit organization	6.390663e-5
GO:0014888	striated muscle adaptation	6.735756e-5
GO:0021678	third ventricle development	7.526093e-5
GO:0006423	cysteinyl-tRNA aminoacylation	7.590452e-5
GO:0022601	menstrual cycle phase	7.888484e-5
GO:0010803	regulation of tumor necrosis factor-mediated signaling pathway	8.600689e-5
GO:0043456	regulation of pentose-phosphate shunt	8.771123e-5
GO:0006544	glycine metabolic process	9.165897e-5
GO:0044332	Wnt receptor signaling pathway involved in dorsal/ventral axis specification	9.909358e-5
GO:0048790	maintenance of presynaptic active zone structure	1.019870e-4
GO:0031630	regulation of synaptic vesicle fusion to presynaptic membrane	1.019870e-4
GO:0006368	transcription elongation from RNA polymerase II promoter	1.021976e-4
GO:0051898	negative regulation of protein kinase B signaling cascade	1.110509e-4
GO:0045200	establishment of neuroblast polarity	1.158732e-4
GO:0006990	positive regulation of transcription from RNA polymerase II promoter involved in unfolded protein response	1.158732e-4
GO:0051313	attachment of spindle microtubules to chromosome	1.188022e-4
GO:2000164	negative regulation of planar cell polarity pathway involved in outflow tract morphogenesis	1.253003e-4
GO:2000166	negative regulation of planar cell polarity pathway involved in pericardium morphogenesis	1.253003e-4
GO:2000168	negative regulation of planar cell polarity pathway involved in neural tube closure	1.253003e-4
GO:2000162	negative regulation of planar cell polarity pathway involved in cardiac right atrium morphogenesis	1.253003e-4
GO:2000055	positive regulation of Wnt receptor signaling pathway involved in dorsal/ventral axis specification	1.253003e-4
GO:0061310	canonical Wnt receptor signaling pathway involved in cardiac neural crest cell differentiation involved in heart development	1.253003e-4
GO:2000149	negative regulation of planar cell polarity pathway involved in ventricular septum morphogenesis	1.253003e-4
GO:2000151	negative regulation of planar cell polarity pathway involved in cardiac muscle tissue morphogenesis	1.253003e-4
GO:0006695	cholesterol biosynthetic process	1.260328e-4
GO:0044340	canonical Wnt receptor signaling pathway involved in regulation of cell proliferation	1.311254e-4
GO:0006354	transcription elongation, DNA-dependent	1.320263e-4
GO:0050434	positive regulation of viral transcription	1.333211e-4
GO:0017145	stem cell division	1.480898e-4
GO:0032211	negative regulation of telomere maintenance via telomerase	1.535215e-4
GO:0007228	positive regulation of hh target transcription factor activity	1.591313e-4
GO:0000236	mitotic prometaphase	1.729955e-4
GO:0010390	histone monoubiquitination	1.748076e-4
GO:0008334	histone mRNA metabolic process	1.774613e-4
GO:0003149	membranous septum morphogenesis	1.775601e-4
GO:0021979	hypothalamus cell differentiation	1.788875e-4
GO:0033084	regulation of immature T cell proliferation in thymus	1.939178e-4
GO:0032094	response to food	2.025521e-4
GO:0046314	phosphocreatine biosynthetic process	2.127673e-4
GO:0006271	DNA strand elongation involved in DNA replication	2.265904e-4
GO:0021795	cerebral cortex cell migration	2.288310e-4
GO:0048708	astrocyte differentiation	2.337125e-4
GO:0050779	RNA destabilization	2.465256e-4
GO:0090281	negative regulation of calcium ion import	2.540161e-4
GO:0071584	negative regulation of zinc ion import	2.540161e-4
GO:0042474	middle ear morphogenesis	2.558683e-4
GO:0033205	cell cycle cytokinesis	2.584330e-4
GO:0021532	neural tube patterning	2.610825e-4
GO:0003218	cardiac left ventricle formation	2.657556e-4
GO:0006457	protein folding	2.681919e-4
GO:0051256	spindle midzone assembly involved in mitosis	2.731327e-4
GO:0035518	histone H2A monoubiquitination	2.732358e-4
GO:0043457	regulation of cellular respiration	2.737173e-4
GO:0021879	forebrain neuron differentiation	2.827653e-4
GO:0070076	histone lysine demethylation	2.859135e-4
GO:0046939	nucleotide phosphorylation	2.933431e-4
GO:0000398	nuclear mRNA splicing, via spliceosome	3.000448e-4
GO:0010836	negative regulation of protein ADP-ribosylation	3.457375e-4
GO:0021937	cerebellar Purkinje cell-granule cell precursor cell signaling involved in regulation of granule cell precursor cell proliferation	3.509601e-4
GO:0090083	regulation of inclusion body assembly	3.618956e-4
GO:0048524	positive regulation of viral reproduction	3.626093e-4
GO:0021796	cerebral cortex regionalization	3.686429e-4
GO:0015696	ammonium transport	3.794371e-4
GO:0006458	'de novo' protein folding	3.876474e-4
GO:0072488	ammonium transmembrane transport	3.898415e-4
GO:0051131	chaperone-mediated protein complex assembly	4.061846e-4
GO:0072144	glomerular mesangial cell development	4.064914e-4
GO:0072011	glomerular endothelium development	4.064914e-4
GO:0090085	regulation of protein deubiquitination	4.077317e-4
GO:0035404	histone-serine phosphorylation	4.116638e-4
GO:0021985	neurohypophysis development	4.263999e-4
GO:0009069	serine family amino acid metabolic process	4.340803e-4
GO:0045739	positive regulation of DNA repair	4.379639e-4
GO:0022616	DNA strand elongation	4.531456e-4
GO:0040040	thermosensory behavior	4.559579e-4
GO:0006513	protein monoubiquitination	4.703878e-4
GO:0060976	coronary vasculature development	4.717479e-4
GO:0072385	minus-end-directed organelle transport along microtubule	4.990868e-4
GO:0042118	endothelial cell activation	4.990868e-4
GO:0044335	canonical Wnt receptor signaling pathway involved in neural crest cell differentiation	5.009444e-4
GO:0035852	horizontal cell localization	5.030565e-4
GO:0035849	nephric duct elongation	5.030565e-4
GO:2000768	positive regulation of nephron tubule epithelial cell differentiation	5.030565e-4
GO:0060450	positive regulation of hindgut contraction	5.030565e-4
GO:0045925	positive regulation of female receptivity	5.030565e-4
GO:0035847	uterine epithelium development	5.030565e-4
GO:0035502	metanephric ureteric bud development	5.030565e-4
GO:0031619	homologous chromosome orientation involved in meiotic metaphase I plate congression	5.030565e-4
GO:0035846	oviduct epithelium development	5.030565e-4
GO:0006264	mitochondrial DNA replication	5.047745e-4
GO:0006268	DNA unwinding involved in replication	5.049978e-4
GO:0021799	cerebral cortex radially oriented cell migration	5.097396e-4
GO:0043585	nose morphogenesis	5.516221e-4
GO:2000466	negative regulation of glycogen (starch) synthase activity	5.612292e-4
GO:0006447	regulation of translational initiation by iron	5.703554e-4
GO:0070194	synaptonemal complex disassembly	5.810820e-4
GO:0031662	positive regulation of cyclin-dependent protein kinase activity involved in G2/M	5.810820e-4
GO:0001805	positive regulation of type III hypersensitivity	5.810820e-4
GO:0002431	Fc receptor mediated stimulatory signaling pathway	5.810820e-4
GO:0030917	midbrain-hindbrain boundary development	5.888999e-4
GO:0016126	sterol biosynthetic process	5.923461e-4
GO:0006281	DNA repair	6.011119e-4
GO:0009070	serine family amino acid biosynthetic process	6.281741e-4
GO:0002037	negative regulation of L-glutamate transport	6.335221e-4
GO:0045994	positive regulation of translational initiation by iron	6.335221e-4
GO:0033209	tumor necrosis factor-mediated signaling pathway	6.367350e-4
GO:0021954	central nervous system neuron development	6.423113e-4
GO:0050832	defense response to fungus	6.511679e-4
GO:0021895	cerebral cortex neuron differentiation	6.562777e-4
GO:0097029	mature dendritic cell differentiation	6.598500e-4
GO:0032055	negative regulation of translation in response to stress	6.744977e-4
GO:0048103	somatic stem cell division	6.893744e-4
GO:0006414	translational elongation	6.911818e-4
GO:0010458	exit from mitosis	7.109528e-4
GO:0042538	hyperosmotic salinity response	7.109528e-4
GO:0010002	cardioblast differentiation	7.109528e-4
GO:0033522	histone H2A ubiquitination	7.364108e-4
GO:0033083	regulation of immature T cell proliferation	7.612755e-4
GO:0051083	'de novo' cotranslational protein folding	7.673910e-4
GO:0002036	regulation of L-glutamate transport	7.807406e-4
GO:0007017	microtubule-based process	7.814995e-4
GO:0032933	SREBP-mediated signaling pathway	7.864607e-4
GO:0072143	mesangial cell development	7.938916e-4
GO:0042254	ribosome biogenesis	8.025222e-4
GO:0021871	forebrain regionalization	8.153326e-4
GO:0051323	metaphase	8.262947e-4
GO:0021592	fourth ventricle development	8.301307e-4
GO:0016574	histone ubiquitination	8.386386e-4
GO:0071542	dopaminergic neuron differentiation	8.452222e-4
GO:0000724	double-strand break repair via homologous recombination	8.618627e-4
GO:0060648	mammary gland bud morphogenesis	8.875463e-4
GO:0035883	enteroendocrine cell differentiation	9.013523e-4
GO:0001732	formation of translation initiation complex	9.167820e-4
GO:0003062	regulation of heart rate by chemical signal	9.223958e-4
GO:0090398	cellular senescence	9.352271e-4
GO:0045684	positive regulation of epidermis development	9.365871e-4
GO:0006364	rRNA processing	9.499255e-4
GO:0046782	regulation of viral transcription	9.519473e-4
GO:0021978	telencephalon regionalization	9.756772e-4
GO:0008298	intracellular mRNA localization	9.858013e-4
GO:0003285	septum secundum development	1.008644e-3
GO:0000305	response to oxygen radical	1.071710e-3
GO:0006432	phenylalanyl-tRNA aminoacylation	1.104650e-3
GO:0046796	viral genome transport in host cell	1.104650e-3
GO:0048251	elastic fiber assembly	1.136628e-3
GO:0000375	RNA splicing, via transesterification reactions	1.149001e-3
GO:0035811	negative regulation of urine volume	1.166946e-3
GO:0034766	negative regulation of ion transmembrane transport	1.173705e-3
GO:0016598	protein arginylation	1.173705e-3
GO:0032392	DNA geometric change	1.180375e-3
GO:0090399	replicative senescence	1.234763e-3
GO:0006298	mismatch repair	1.240349e-3
GO:0006308	DNA catabolic process	1.275043e-3
GO:0045047	protein targeting to ER	1.291864e-3
GO:0000725	recombinational repair	1.318690e-3
GO:0032210	regulation of telomere maintenance via telomerase	1.346969e-3
GO:0042423	catecholamine biosynthetic process	1.368097e-3
GO:0048280	vesicle fusion with Golgi apparatus	1.395546e-3
GO:0050703	interleukin-1 alpha secretion	1.400844e-3
GO:0006418	tRNA aminoacylation for protein translation	1.404445e-3
GO:0010463	mesenchymal cell proliferation	1.426600e-3
GO:0031064	negative regulation of histone deacetylation	1.428430e-3
GO:0015693	magnesium ion transport	1.451876e-3
GO:0009155	purine deoxyribonucleotide catabolic process	1.468674e-3
GO:0000093	mitotic telophase	1.468674e-3
GO:0032057	negative regulation of translational initiation in response to stress	1.480359e-3
GO:0090118	receptor-mediated endocytosis of low-density lipoprotein particle involved in cholesterol transport	1.480359e-3
GO:0006284	base-excision repair	1.481218e-3
GO:0061316	canonical Wnt receptor signaling pathway involved in heart development	1.481908e-3
GO:0014044	Schwann cell development	1.494344e-3
GO:0045143	homologous chromosome segregation	1.513430e-3
GO:0061050	regulation of cell growth involved in cardiac muscle cell development	1.533388e-3
GO:0009804	coumarin metabolic process	1.533388e-3
GO:0035308	negative regulation of protein dephosphorylation	1.534934e-3
GO:0051798	positive regulation of hair follicle development	1.555104e-3
GO:0060381	positive regulation of single-stranded telomeric DNA binding	1.589738e-3
GO:0014037	Schwann cell differentiation	1.601025e-3
GO:0001878	response to yeast	1.629220e-3
GO:0071169	establishment of protein localization to chromatin	1.650363e-3
GO:0048291	isotype switching to IgG isotypes	1.650363e-3
GO:0002842	positive regulation of T cell mediated immune response to tumor cell	1.650363e-3
GO:0002368	B cell cytokine production	1.650363e-3
GO:0009451	RNA modification	1.661965e-3
GO:0061205	paramesonephric duct development	1.665210e-3
GO:0002331	pre-B cell allelic exclusion	1.665210e-3
GO:0000303	response to superoxide	1.700228e-3
GO:0000414	regulation of histone H3-K36 methylation	1.767739e-3
GO:0051791	medium-chain fatty acid metabolic process	1.789621e-3
GO:0033490	cholesterol biosynthetic process via lathosterol	1.789621e-3
GO:0050720	interleukin-1 beta biosynthetic process	1.789621e-3
GO:0019428	allantoin biosynthetic process	1.789621e-3
GO:0000480	endonucleolytic cleavage in 5'-ETS of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)	1.789621e-3
GO:0000472	endonucleolytic cleavage to generate mature 5'-end of SSU-rRNA from (SSU-rRNA, 5.8S rRNA, LSU-rRNA)	1.789621e-3
GO:0051081	nuclear envelope disassembly	1.822595e-3
GO:0007506	gonadal mesoderm development	1.822595e-3
GO:0042053	regulation of dopamine metabolic process	1.829303e-3
GO:0046813	virion attachment, binding of host cell surface receptor	1.834952e-3
GO:0061324	canonical Wnt receptor signaling pathway involved in positive regulation of cardiac outflow tract cell proliferation	1.834952e-3
GO:0030237	female sex determination	1.834952e-3
GO:0016056	rhodopsin mediated signaling pathway	1.834952e-3
GO:0021872	forebrain generation of neurons	1.869276e-3
GO:0072393	microtubule anchoring at microtubule organizing center	1.904591e-3
GO:0002876	positive regulation of chronic inflammatory response to antigenic stimulus	1.904591e-3
GO:0070574	cadmium ion transmembrane transport	1.913989e-3
GO:0051572	negative regulation of histone H3-K4 methylation	1.941543e-3
GO:0045820	negative regulation of glycolysis	1.946479e-3
GO:0015886	heme transport	2.015973e-3
GO:0019062	virion attachment to host cell surface receptor	2.036492e-3
GO:0060659	nipple sheath formation	2.043466e-3
GO:0060649	mammary gland bud elongation	2.043466e-3
GO:0060430	lung saccule development	2.044152e-3
GO:0007198	inhibition of adenylate cyclase activity by serotonin receptor signaling pathway	2.058256e-3
GO:0060213	positive regulation of nuclear-transcribed mRNA poly(A) tail shortening	2.098821e-3
GO:0002536	respiratory burst involved in inflammatory response	2.181722e-3
GO:0060977	coronary vasculature morphogenesis	2.197686e-3
GO:0043584	nose development	2.231840e-3
GO:0043249	erythrocyte maturation	2.272054e-3
GO:0000022	mitotic spindle elongation	2.279903e-3
GO:0015684	ferrous iron transport	2.398098e-3
GO:0019478	D-amino acid catabolic process	2.400732e-3
GO:0051972	regulation of telomerase activity	2.412911e-3
GO:0006853	carnitine shuttle	2.422313e-3
GO:0000415	negative regulation of histone H3-K36 methylation	2.427320e-3
GO:0060397	JAK-STAT cascade involved in growth hormone signaling pathway	2.482672e-3
GO:0033085	negative regulation of T cell differentiation in thymus	2.482672e-3
GO:0060428	lung epithelium development	2.483223e-3
GO:0085029	extracellular matrix assembly	2.557084e-3
GO:0016072	rRNA metabolic process	2.557118e-3
GO:0006548	histidine catabolic process	2.610175e-3
GO:0035116	embryonic hindlimb morphogenesis	2.631899e-3
GO:0030010	establishment of cell polarity	2.689981e-3
GO:0022011	myelination in peripheral nervous system	2.690868e-3
GO:0061051	positive regulation of cell growth involved in cardiac muscle cell development	2.712735e-3
GO:0003061	positive regulation of the force of heart contraction by norepinephrine	2.712735e-3
GO:0021528	commissural neuron differentiation in spinal cord	2.712735e-3
GO:0003016	respiratory system process	2.713164e-3
GO:0031167	rRNA methylation	2.721452e-3
GO:0042274	ribosomal small subunit biogenesis	2.749833e-3
GO:0034259	negative regulation of Rho GTPase activity	2.759984e-3
GO:0022007	convergent extension involved in neural plate elongation	2.759984e-3
GO:0002074	extraocular skeletal muscle development	2.759984e-3
GO:0000154	rRNA modification	2.809701e-3
GO:0032007	negative regulation of TOR signaling cascade	2.937887e-3
GO:0060535	trachea cartilage morphogenesis	2.993229e-3
GO:0042696	menarche	3.018190e-3
GO:0048752	semicircular canal morphogenesis	3.025518e-3
GO:0003140	determination of left/right asymmetry in lateral mesoderm	3.044284e-3
GO:0034453	microtubule anchoring	3.059572e-3
GO:0042069	regulation of catecholamine metabolic process	3.087790e-3
GO:0042590	antigen processing and presentation of exogenous peptide antigen via MHC class I	3.116409e-3
GO:0009071	serine family amino acid catabolic process	3.150631e-3
GO:0009264	deoxyribonucleotide catabolic process	3.150631e-3
GO:0051255	spindle midzone assembly	3.185066e-3
GO:0007498	mesoderm development	3.247075e-3
GO:0021555	midbrain-hindbrain boundary morphogenesis	3.275086e-3
GO:0021537	telencephalon development	3.368003e-3
GO:0060356	leucine import	3.515397e-3
GO:0040032	post-embryonic body morphogenesis	3.549198e-3
GO:0001710	mesodermal cell fate commitment	3.643869e-3
GO:0051301	cell division	3.648049e-3
GO:0031572	G2/M transition DNA damage checkpoint	3.677284e-3
GO:0006828	manganese ion transport	3.745542e-3
GO:0060486	Clara cell differentiation	3.748686e-3
GO:0006780	uroporphyrinogen III biosynthetic process	3.772845e-3
GO:0061101	neuroendocrine cell differentiation	3.774710e-3
GO:0018209	peptidyl-serine modification	3.787075e-3
GO:0021993	initiation of neural tube closure	3.863619e-3
GO:0042396	phosphagen biosynthetic process	3.898982e-3
GO:0002052	positive regulation of neuroblast proliferation	3.931790e-3
GO:0033081	regulation of T cell differentiation in thymus	3.955875e-3
GO:0006270	DNA-dependent DNA replication initiation	3.959375e-3
GO:0061084	negative regulation of protein refolding	3.974083e-3
GO:0072109	glomerular mesangium development	3.974083e-3
GO:0070407	oxidation-dependent protein catabolic process	4.064988e-3
GO:0006272	leading strand elongation	4.064988e-3
GO:0000281	cytokinesis after mitosis	4.099131e-3
GO:0006563	L-serine metabolic process	4.151551e-3
GO:0017183	peptidyl-diphthamide biosynthetic process from peptidyl-histidine	4.177222e-3
GO:0051589	negative regulation of neurotransmitter transport	4.387783e-3
GO:0003221	right ventricular cardiac muscle tissue morphogenesis	4.451054e-3
GO:0010624	regulation of Schwann cell proliferation	4.470043e-3
GO:0060947	cardiac vascular smooth muscle cell differentiation	4.527411e-3
GO:0043241	protein complex disassembly	4.528626e-3
GO:0021905	forebrain-midbrain boundary formation	4.596294e-3
GO:0021918	regulation of transcription from RNA polymerase II promoter involved in somatic motor neuron fate commitment	4.596294e-3
GO:0014028	notochord formation	4.596294e-3
GO:0021902	commitment of neuronal cell to specific neuron type in forebrain	4.596294e-3
GO:0003322	pancreatic A cell development	4.596294e-3
GO:0007141	male meiosis I	4.611945e-3
GO:0006241	CTP biosynthetic process	4.611945e-3
GO:0006047	UDP-N-acetylglucosamine metabolic process	4.611945e-3
GO:0042249	establishment of planar polarity of embryonic epithelium	4.645698e-3
GO:0018105	peptidyl-serine phosphorylation	4.670466e-3
GO:0045104	intermediate filament cytoskeleton organization	4.809933e-3
GO:0060693	regulation of branching involved in salivary gland morphogenesis	4.818080e-3
GO:0032508	DNA duplex unwinding	4.843653e-3
GO:0042059	negative regulation of epidermal growth factor receptor signaling pathway	4.885693e-3
GO:0046718	entry of virus into host cell	4.984296e-3
GO:0032259	methylation	5.014996e-3
GO:0021893	cerebral cortex GABAergic interneuron fate commitment	5.019673e-3
GO:0021882	regulation of transcription from RNA polymerase II promoter involved in forebrain neuron fate commitment	5.019673e-3
GO:0032717	negative regulation of interleukin-8 production	5.117502e-3
GO:0060534	trachea cartilage development	5.120392e-3
GO:0010816	calcitonin catabolic process	5.260435e-3
GO:0034959	endothelin maturation	5.260435e-3
GO:0010814	substance P catabolic process	5.260435e-3
GO:0051084	'de novo' posttranslational protein folding	5.397377e-3
GO:0048702	embryonic neurocranium morphogenesis	5.535692e-3
GO:0071421	manganese ion transmembrane transport	5.547910e-3
GO:0007259	JAK-STAT cascade	5.597307e-3
GO:0030579	ubiquitin-dependent SMAD protein catabolic process	5.615554e-3
GO:0070943	neutrophil mediated killing of symbiont cell	5.674099e-3
GO:0042074	cell migration involved in gastrulation	5.686379e-3
GO:0032516	positive regulation of phosphoprotein phosphatase activity	5.706410e-3
GO:0006014	D-ribose metabolic process	5.712784e-3
GO:0048050	post-embryonic eye morphogenesis	5.787672e-3
GO:0002502	peptide antigen assembly with MHC class I protein complex	5.787672e-3
GO:0033088	negative regulation of immature T cell proliferation in thymus	5.803264e-3
GO:0034969	histone arginine methylation	5.839340e-3
GO:0051793	medium-chain fatty acid catabolic process	5.946256e-3
GO:0042450	arginine biosynthetic process via ornithine	5.946256e-3
GO:0006781	succinyl-CoA pathway	5.946256e-3
GO:0033260	DNA replication involved in S phase	5.946256e-3
GO:0060020	Bergmann glial cell differentiation	5.947138e-3
GO:0043990	histone H2A-S1 phosphorylation	5.956235e-3
GO:0002508	central tolerance induction	5.956235e-3
GO:0002897	positive regulation of central B cell tolerance induction	5.956235e-3
GO:0006398	histone mRNA 3'-end processing	5.962860e-3
GO:0048665	neuron fate specification	6.008341e-3
GO:0002635	negative regulation of germinal center formation	6.051678e-3
GO:0070102	interleukin-6-mediated signaling pathway	6.057095e-3
GO:0016188	synaptic vesicle maturation	6.126950e-3
GO:0071585	detoxification of cadmium ion	6.144847e-3
GO:0070537	histone H2A K63-linked deubiquitination	6.144847e-3
GO:0007051	spindle organization	6.231667e-3
GO:0070198	protein localization to chromosome, telomeric region	6.263126e-3
GO:0021520	spinal cord motor neuron cell fate specification	6.282387e-3
GO:0071042	nuclear polyadenylation-dependent mRNA catabolic process	6.317750e-3
GO:2000627	positive regulation of miRNA catabolic process	6.317750e-3
GO:0000964	mitochondrial RNA 5'-end processing	6.317750e-3
GO:0042703	menstruation	6.317750e-3
GO:0033299	secretion of lysosomal enzymes	6.317750e-3
GO:0019101	female somatic sex determination	6.317750e-3
GO:0044070	regulation of anion transport	6.352011e-3
GO:0007418	ventral midline development	6.357623e-3
GO:0006244	pyrimidine nucleotide catabolic process	6.357623e-3
GO:0045132	meiotic chromosome segregation	6.398776e-3
GO:0060021	palate development	6.406858e-3
GO:0032202	telomere assembly	6.531453e-3
GO:0048715	negative regulation of oligodendrocyte differentiation	6.618780e-3
GO:0045682	regulation of epidermis development	6.636588e-3
GO:0008054	cyclin catabolic process	6.664608e-3
GO:0008380	RNA splicing	6.754517e-3
GO:0021938	smoothened signaling pathway involved in regulation of cerebellar granule cell precursor cell proliferation	6.829727e-3
GO:0021523	somatic motor neuron differentiation	6.977748e-3
GO:0046778	modification by virus of host mRNA processing	6.998396e-3
GO:0043586	tongue development	7.132399e-3
GO:0046532	regulation of photoreceptor cell differentiation	7.222136e-3
GO:0019919	peptidyl-arginine methylation, to asymmetrical-dimethyl arginine	7.250163e-3
GO:0042149	cellular response to glucose starvation	7.253272e-3
GO:2000124	regulation of endocannabinoid signaling pathway	7.289172e-3
GO:0030490	maturation of SSU-rRNA	7.296641e-3
GO:0060059	embryonic retina morphogenesis in camera-type eye	7.305741e-3
GO:0006488	dolichol-linked oligosaccharide biosynthetic process	7.433655e-3
GO:0051026	chiasma assembly	7.574608e-3
GO:0032912	negative regulation of transforming growth factor beta2 production	7.574608e-3
GO:0051974	negative regulation of telomerase activity	7.608436e-3
GO:0060439	trachea morphogenesis	7.692815e-3
GO:0070914	UV-damage excision repair	7.699282e-3
GO:0060695	negative regulation of cholesterol transporter activity	7.699282e-3
GO:0001812	positive regulation of type I hypersensitivity	7.699282e-3
GO:0003222	ventricular trabecular myocardium morphogenesis	7.699282e-3
GO:0014029	neural crest formation	7.712402e-3
GO:0021885	forebrain cell migration	7.727509e-3
GO:0072111	cell proliferation involved in kidney development	7.761373e-3
GO:0030262	apoptotic nuclear change	7.874273e-3
GO:0048663	neuron fate commitment	7.997761e-3
GO:0035137	hindlimb morphogenesis	8.023355e-3
GO:0021869	forebrain ventricular zone progenitor cell division	8.030740e-3
GO:0008608	attachment of spindle microtubules to kinetochore	8.099978e-3
GO:0033092	positive regulation of immature T cell proliferation in thymus	8.099978e-3
GO:0072285	mesenchymal to epithelial transition involved in metanephric renal vesicle formation	8.206782e-3
GO:0060830	ciliary receptor clustering involved in smoothened signaling pathway	8.206782e-3
GO:0007371	ventral midline determination	8.206782e-3
GO:0060248	detection of cell density by contact stimulus involved in contact inhibition	8.206782e-3
GO:0045358	negative regulation of interferon-beta biosynthetic process	8.206782e-3
GO:0031077	post-embryonic camera-type eye development	8.275154e-3
GO:0070368	positive regulation of hepatocyte differentiation	8.352776e-3
GO:0035262	gonad morphogenesis	8.390867e-3
GO:0006361	transcription initiation from RNA polymerase I promoter	8.430861e-3
GO:0090279	regulation of calcium ion import	8.527127e-3
GO:0060768	regulation of epithelial cell proliferation involved in prostate gland development	8.716356e-3
GO:0002098	tRNA wobble uridine modification	8.764873e-3
GO:0034227	tRNA thio-modification	8.764873e-3
GO:0090224	regulation of spindle organization	8.772432e-3
GO:0070534	protein K63-linked ubiquitination	8.907049e-3
GO:0045329	carnitine biosynthetic process	8.977749e-3
GO:0071422	succinate transmembrane transport	9.023332e-3
GO:0060837	blood vessel endothelial cell differentiation	9.023332e-3
GO:0008636	activation of caspase activity by protein phosphorylation	9.023332e-3
GO:0035409	histone H3-Y41 phosphorylation	9.023332e-3
GO:0050689	negative regulation of defense response to virus by host	9.023332e-3
GO:0035247	peptidyl-arginine omega-N-methylation	9.060072e-3
GO:0006657	CDP-choline pathway	9.269527e-3
GO:0072203	cell proliferation involved in metanephros development	9.273759e-3
GO:0010923	negative regulation of phosphatase activity	9.356844e-3
GO:0003311	pancreatic D cell differentiation	9.366283e-3
GO:0090104	pancreatic E cell differentiation	9.366283e-3
GO:0034241	positive regulation of macrophage fusion	9.456273e-3
GO:0032915	positive regulation of transforming growth factor beta2 production	9.456273e-3
GO:0042407	cristae formation	9.456273e-3
GO:0000354	cis assembly of pre-catalytic spliceosome	9.456273e-3
GO:0016191	synaptic vesicle uncoating	9.456273e-3
GO:0001546	preantral ovarian follicle growth	9.456273e-3
GO:0003257	positive regulation of transcription from RNA polymerase II promoter involved in myocardial precursor cell differentiation	9.456273e-3
GO:2001037	positive regulation of tongue muscle cell differentiation	9.514551e-3

GREAT analysis results for mouseGenomic Enrichment of Annotations Tool (GREAT, Nat Biotechnol. 2010 May;28(5):495-501) is used to identify, both in human and in mouse, the gene ontology terms of biological processes enriched given the predicted TFBSs, and evaluated the overlap in the top-500 gene ontology terms between human and mouse. For each novel motif, the P value for the overlap was then evaluated by calculating its relative rank with respect to this background distribution.<br>Analyst: Michiel de Hoon <br><br>link to source dataset <br>data

---

GO ID	GO Term	p-value
GO:0043653	mitochondrial fragmentation involved in apoptosis	1.659437e-10
GO:0090083	regulation of inclusion body assembly	2.432606e-9
GO:0022403	cell cycle phase	7.205411e-9
GO:0000279	M phase	9.058893e-9
GO:0034587	piRNA metabolic process	6.449297e-7
GO:0002483	antigen processing and presentation of endogenous peptide antigen	7.480708e-7
GO:0030240	skeletal muscle thin filament assembly	8.695884e-7
GO:0090084	negative regulation of inclusion body assembly	8.734399e-7
GO:0022402	cell cycle process	1.366990e-6
GO:0007051	spindle organization	1.956692e-6
GO:0046477	glycosylceramide catabolic process	2.822923e-6
GO:0071542	dopaminergic neuron differentiation	2.866719e-6
GO:0014866	skeletal myofibril assembly	3.067816e-6
GO:0042472	inner ear morphogenesis	5.265881e-6
GO:0060005	vestibular reflex	6.334939e-6
GO:0019885	antigen processing and presentation of endogenous peptide antigen via MHC class I	7.219824e-6
GO:0007214	gamma-aminobutyric acid signaling pathway	1.082307e-5
GO:0070534	protein K63-linked ubiquitination	1.151261e-5
GO:0051964	negative regulation of synapse assembly	1.329820e-5
GO:0006646	phosphatidylethanolamine biosynthetic process	1.679502e-5
GO:0000087	M phase of mitotic cell cycle	1.688884e-5
GO:0051661	maintenance of centrosome location	1.860052e-5
GO:0006463	steroid hormone receptor complex assembly	2.010970e-5
GO:0061084	negative regulation of protein refolding	2.044021e-5
GO:0042471	ear morphogenesis	2.290661e-5
GO:0051961	negative regulation of nervous system development	2.662979e-5
GO:0021953	central nervous system neuron differentiation	2.917064e-5
GO:0043503	skeletal muscle fiber adaptation	3.069030e-5
GO:0051030	snRNA transport	3.185424e-5
GO:0007032	endosome organization	3.282011e-5
GO:0060658	nipple morphogenesis	4.001628e-5
GO:0009650	UV protection	4.517339e-5
GO:0048285	organelle fission	4.564340e-5
GO:0090086	negative regulation of protein deubiquitination	4.856092e-5
GO:0048741	skeletal muscle fiber development	4.912180e-5
GO:0051645	Golgi localization	6.128438e-5
GO:0048752	semicircular canal morphogenesis	6.226423e-5
GO:0021528	commissural neuron differentiation in spinal cord	6.311513e-5
GO:0046847	filopodium assembly	7.516793e-5
GO:0007067	mitosis	8.641085e-5
GO:0002098	tRNA wobble uridine modification	8.651902e-5
GO:0046479	glycosphingolipid catabolic process	9.832354e-5
GO:0000278	mitotic cell cycle	1.089508e-4
GO:0006680	glucosylceramide catabolic process	1.185752e-4
GO:0070286	axonemal dynein complex assembly	1.378120e-4
GO:0090311	regulation of protein deacetylation	1.384319e-4
GO:0085020	protein K6-linked ubiquitination	1.393558e-4
GO:0034660	ncRNA metabolic process	1.456207e-4
GO:0031503	protein complex localization	1.605213e-4
GO:0031063	regulation of histone deacetylation	1.615166e-4
GO:0015986	ATP synthesis coupled proton transport	1.972007e-4
GO:0030035	microspike assembly	2.201104e-4
GO:0033627	cell adhesion mediated by integrin	2.207922e-4
GO:0006172	ADP biosynthetic process	2.225281e-4
GO:0046039	GTP metabolic process	2.343706e-4
GO:0000375	RNA splicing, via transesterification reactions	2.360235e-4
GO:0000492	box C/D snoRNP assembly	2.425472e-4
GO:0033044	regulation of chromosome organization	2.427865e-4
GO:0090103	cochlea morphogenesis	2.913312e-4
GO:0046967	cytosol to ER transport	3.090841e-4
GO:0019060	intracellular transport of viral proteins in host cell	3.090841e-4
GO:0045292	nuclear mRNA cis splicing, via spliceosome	3.095891e-4
GO:0090182	regulation of secretion of lysosomal enzymes	3.163361e-4
GO:0051684	maintenance of Golgi location	3.163361e-4
GO:0090186	regulation of pancreatic juice secretion	3.163361e-4
GO:0048550	negative regulation of pinocytosis	3.163361e-4
GO:0050983	deoxyhypusine biosynthetic process from spermidine, using deoxyhypusine synthase	3.163361e-4
GO:0090329	regulation of DNA-dependent DNA replication	3.192742e-4
GO:0090179	planar cell polarity pathway involved in neural tube closure	3.192742e-4
GO:0045083	negative regulation of interleukin-12 biosynthetic process	3.411571e-4
GO:0008033	tRNA processing	3.463758e-4
GO:0007140	male meiosis	3.508571e-4
GO:0060872	semicircular canal development	3.513994e-4
GO:0090234	regulation of kinetochore assembly	3.600611e-4
GO:0007497	posterior midgut development	3.600611e-4
GO:0090169	regulation of spindle assembly	3.600611e-4
GO:0030719	P granule organization	3.600611e-4
GO:0035645	enteric smooth muscle cell differentiation	3.600611e-4
GO:0045218	zonula adherens maintenance	3.634779e-4
GO:0043610	regulation of carbohydrate utilization	3.662524e-4
GO:0006409	tRNA export from nucleus	3.662524e-4
GO:0007398	ectoderm development	3.705690e-4
GO:0032513	negative regulation of protein phosphatase type 2B activity	3.748878e-4
GO:0048852	diencephalon morphogenesis	3.814258e-4
GO:0009220	pyrimidine ribonucleotide biosynthetic process	3.909921e-4
GO:0051091	positive regulation of sequence-specific DNA binding transcription factor activity	4.037087e-4
GO:0042053	regulation of dopamine metabolic process	4.090845e-4
GO:0006399	tRNA metabolic process	4.114137e-4
GO:0021879	forebrain neuron differentiation	4.233866e-4
GO:0050428	3'-phosphoadenosine 5'-phosphosulfate biosynthetic process	4.455912e-4
GO:0009798	axis specification	4.551248e-4
GO:0009880	embryonic pattern specification	4.551732e-4
GO:0006893	Golgi to plasma membrane transport	4.839153e-4
GO:0048843	negative regulation of axon extension involved in axon guidance	5.109761e-4
GO:0048839	inner ear development	5.120242e-4
GO:0003323	type B pancreatic cell development	5.142431e-4
GO:0021954	central nervous system neuron development	5.151115e-4
GO:0007017	microtubule-based process	5.269627e-4
GO:0006670	sphingosine metabolic process	5.504458e-4
GO:0018065	protein-cofactor linkage	5.515111e-4
GO:0018243	protein O-linked glycosylation via threonine	5.515111e-4
GO:0018242	protein O-linked glycosylation via serine	5.515111e-4
GO:0050427	3'-phosphoadenosine 5'-phosphosulfate metabolic process	5.556224e-4
GO:0043316	cytotoxic T cell degranulation	5.716146e-4
GO:0070079	histone H4-R3 demethylation	5.716146e-4
GO:0070078	histone H3-R2 demethylation	5.716146e-4
GO:0018395	peptidyl-lysine hydroxylation to 5-hydroxy-L-lysine	5.716146e-4
GO:0006408	snRNA export from nucleus	5.716146e-4
GO:0034227	tRNA thio-modification	5.740993e-4
GO:0021871	forebrain regionalization	6.013998e-4
GO:0043001	Golgi to plasma membrane protein transport	6.236753e-4
GO:0032886	regulation of microtubule-based process	6.344455e-4
GO:0015696	ammonium transport	6.472744e-4
GO:0060067	cervix development	6.792562e-4
GO:0009950	dorsal/ventral axis specification	6.806249e-4
GO:0016049	cell growth	7.017772e-4
GO:0007076	mitotic chromosome condensation	7.032880e-4
GO:0030517	negative regulation of axon extension	7.583595e-4
GO:0051497	negative regulation of stress fiber assembly	7.695720e-4
GO:0051549	positive regulation of keratinocyte migration	7.867301e-4
GO:0060119	inner ear receptor cell development	8.001170e-4
GO:0006184	GTP catabolic process	8.212452e-4
GO:0000070	mitotic sister chromatid segregation	8.320836e-4
GO:0009207	purine ribonucleoside triphosphate catabolic process	8.389403e-4
GO:0051775	response to redox state	8.516529e-4
GO:0042137	sequestering of neurotransmitter	8.516529e-4
GO:0060285	ciliary cell motility	8.796977e-4
GO:0051382	kinetochore assembly	8.933535e-4
GO:0015780	nucleotide-sugar transport	9.057701e-4
GO:0009154	purine ribonucleotide catabolic process	9.738324e-4
GO:0070245	positive regulation of thymocyte apoptosis	1.000937e-3
GO:0060122	inner ear receptor stereocilium organization	1.023218e-3
GO:0006493	protein O-linked glycosylation	1.064167e-3
GO:0009143	nucleoside triphosphate catabolic process	1.144237e-3
GO:0051225	spindle assembly	1.191527e-3
GO:0002485	antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway, TAP-dependent	1.194891e-3
GO:0009218	pyrimidine ribonucleotide metabolic process	1.203652e-3
GO:0070634	transepithelial ammonium transport	1.209653e-3
GO:0030885	regulation of myeloid dendritic cell activation	1.215552e-3
GO:0032782	bile acid secretion	1.215552e-3
GO:0042231	interleukin-13 biosynthetic process	1.215552e-3
GO:2000256	positive regulation of male germ cell proliferation	1.215552e-3
GO:0018293	protein-FAD linkage	1.215552e-3
GO:0006121	mitochondrial electron transport, succinate to ubiquinone	1.215552e-3
GO:0001579	medium-chain fatty acid transport	1.215552e-3
GO:0003096	renal sodium ion transport	1.215552e-3
GO:0032088	negative regulation of NF-kappaB transcription factor activity	1.271040e-3
GO:0006457	protein folding	1.280685e-3
GO:0034655	nucleobase-containing compound catabolic process	1.285135e-3
GO:0060555	induction of necroptosis by extracellular signals	1.342163e-3
GO:0051321	meiotic cell cycle	1.370477e-3
GO:2000104	negative regulation of DNA-dependent DNA replication	1.379083e-3
GO:0000398	nuclear mRNA splicing, via spliceosome	1.380512e-3
GO:0010940	positive regulation of necrotic cell death	1.394384e-3
GO:0009146	purine nucleoside triphosphate catabolic process	1.409376e-3
GO:0009261	ribonucleotide catabolic process	1.461003e-3
GO:0060445	branching involved in salivary gland morphogenesis	1.473512e-3
GO:0009166	nucleotide catabolic process	1.508818e-3
GO:0006657	CDP-choline pathway	1.539893e-3
GO:0072104	glomerular capillary formation	1.559649e-3
GO:0042069	regulation of catecholamine metabolic process	1.571923e-3
GO:0034021	response to silicon dioxide	1.582441e-3
GO:0048773	erythrophore differentiation	1.582441e-3
GO:2000688	positive regulation of rubidium ion transmembrane transporter activity	1.582441e-3
GO:2000682	positive regulation of rubidium ion transport	1.582441e-3
GO:0035826	rubidium ion transport	1.582441e-3
GO:0016078	tRNA catabolic process	1.582441e-3
GO:0001682	tRNA 5'-leader removal	1.582441e-3
GO:0001315	age-dependent response to reactive oxygen species	1.582441e-3
GO:0003069	vasodilation by acetylcholine involved in regulation of systemic arterial blood pressure	1.582441e-3
GO:0034641	cellular nitrogen compound metabolic process	1.585035e-3
GO:0080164	regulation of nitric oxide metabolic process	1.585437e-3
GO:0006683	galactosylceramide catabolic process	1.585437e-3
GO:0043623	cellular protein complex assembly	1.631079e-3
GO:0006195	purine nucleotide catabolic process	1.703939e-3
GO:0072277	metanephric glomerular capillary formation	1.708392e-3
GO:0007352	zygotic specification of dorsal/ventral axis	1.708392e-3
GO:0008334	histone mRNA metabolic process	1.744940e-3
GO:0051647	nucleus localization	1.778212e-3
GO:0048339	paraxial mesoderm development	1.805619e-3
GO:0009259	ribonucleotide metabolic process	1.837960e-3
GO:0021884	forebrain neuron development	1.849902e-3
GO:0006163	purine nucleotide metabolic process	1.878617e-3
GO:0032416	negative regulation of sodium:hydrogen antiporter activity	1.937455e-3
GO:0007369	gastrulation	1.997174e-3
GO:0010458	exit from mitosis	2.094095e-3
GO:0060033	anatomical structure regression	2.099784e-3
GO:0090085	regulation of protein deubiquitination	2.105986e-3
GO:0032606	type I interferon production	2.146424e-3
GO:0007258	JUN phosphorylation	2.146424e-3
GO:0060071	Wnt receptor signaling pathway, planar cell polarity pathway	2.227425e-3
GO:0070234	positive regulation of T cell apoptosis	2.250955e-3
GO:0051572	negative regulation of histone H3-K4 methylation	2.294168e-3
GO:0060806	negative regulation of cell differentiation involved in embryonic placenta development	2.359941e-3
GO:0043928	exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay	2.359941e-3
GO:0000147	actin cortical patch assembly	2.359941e-3
GO:0006433	prolyl-tRNA aminoacylation	2.359941e-3
GO:0006139	nucleobase-containing compound metabolic process	2.371697e-3
GO:0030033	microvillus assembly	2.393501e-3
GO:0009948	anterior/posterior axis specification	2.448114e-3
GO:0021986	habenula development	2.451439e-3
GO:0072523	purine-containing compound catabolic process	2.517212e-3
GO:0060286	flagellar cell motility	2.537884e-3
GO:0046502	uroporphyrinogen III metabolic process	2.537884e-3
GO:0042697	menopause	2.547578e-3
GO:0000226	microtubule cytoskeleton organization	2.551675e-3
GO:0060534	trachea cartilage development	2.702729e-3
GO:0006818	hydrogen transport	2.741766e-3
GO:0033120	positive regulation of RNA splicing	2.759857e-3
GO:0015992	proton transport	2.834723e-3
GO:0002474	antigen processing and presentation of peptide antigen via MHC class I	2.838954e-3
GO:2000729	positive regulation of mesenchymal cell proliferation involved in ureter development	2.862700e-3
GO:0015879	carnitine transport	2.862700e-3
GO:0031536	positive regulation of exit from mitosis	2.862700e-3
GO:0021872	forebrain generation of neurons	2.910154e-3
GO:0009129	pyrimidine nucleoside monophosphate metabolic process	3.006822e-3
GO:0001539	ciliary or flagellar motility	3.006822e-3
GO:0001707	mesoderm formation	3.006990e-3
GO:0072500	negative regulation of transcription from RNA polymerase II promoter by nuclear hormone receptor	3.028489e-3
GO:0071340	skeletal muscle nicotinic acetylcholine receptor clustering	3.028489e-3
GO:0048478	replication fork protection	3.028489e-3
GO:0017038	protein import	3.033831e-3
GO:0002052	positive regulation of neuroblast proliferation	3.127134e-3
GO:0003344	pericardium morphogenesis	3.170259e-3
GO:0043584	nose development	3.287121e-3
GO:0001672	regulation of chromatin assembly or disassembly	3.290947e-3
GO:2000049	positive regulation of cell-cell adhesion mediated by cadherin	3.290947e-3
GO:0006265	DNA topological change	3.303023e-3
GO:0009205	purine ribonucleoside triphosphate metabolic process	3.310016e-3
GO:0009199	ribonucleoside triphosphate metabolic process	3.327319e-3
GO:0008361	regulation of cell size	3.377843e-3
GO:0019348	dolichol metabolic process	3.386234e-3
GO:0018126	protein hydroxylation	3.386234e-3
GO:0032465	regulation of cytokinesis	3.409542e-3
GO:0031047	gene silencing by RNA	3.445824e-3
GO:0051654	establishment of mitochondrion localization	3.473274e-3
GO:0060751	branch elongation involved in mammary gland duct branching	3.484384e-3
GO:0060560	developmental growth involved in morphogenesis	3.502425e-3
GO:0044270	cellular nitrogen compound catabolic process	3.532776e-3
GO:0003306	Wnt receptor signaling pathway involved in heart development	3.549717e-3
GO:0003188	heart valve formation	3.621127e-3
GO:0045995	regulation of embryonic development	3.791269e-3
GO:0006222	UMP biosynthetic process	3.829680e-3
GO:2000649	regulation of sodium ion transmembrane transporter activity	3.835843e-3
GO:0051344	negative regulation of cyclic-nucleotide phosphodiesterase activity	3.849630e-3
GO:0060217	hemangioblast cell differentiation	3.849630e-3
GO:0045799	positive regulation of chromatin assembly or disassembly	3.849630e-3
GO:0019287	isopentenyl diphosphate biosynthetic process, mevalonate pathway	3.849630e-3
GO:0018158	protein oxidation	3.849630e-3
GO:0022417	protein maturation by protein folding	3.849630e-3
GO:0009150	purine ribonucleotide metabolic process	3.850147e-3
GO:0031111	negative regulation of microtubule polymerization or depolymerization	3.876952e-3
GO:0045787	positive regulation of cell cycle	3.894504e-3
GO:0030970	retrograde protein transport, ER to cytosol	4.000166e-3
GO:0001704	formation of primary germ layer	4.021430e-3
GO:0046700	heterocycle catabolic process	4.108287e-3
GO:0060068	vagina development	4.135122e-3
GO:0007431	salivary gland development	4.168554e-3
GO:0060659	nipple sheath formation	4.175960e-3
GO:0008216	spermidine metabolic process	4.175960e-3
GO:0060649	mammary gland bud elongation	4.175960e-3
GO:0071242	cellular response to ammonium ion	4.182414e-3
GO:0018206	peptidyl-methionine modification	4.182414e-3
GO:0010994	free ubiquitin chain polymerization	4.182414e-3
GO:0002476	antigen processing and presentation of endogenous peptide antigen via MHC class Ib	4.182414e-3
GO:0060666	dichotomous subdivision of terminal units involved in salivary gland branching	4.197091e-3
GO:0010467	gene expression	4.199689e-3
GO:0016126	sterol biosynthetic process	4.216134e-3
GO:0031058	positive regulation of histone modification	4.502401e-3
GO:0042994	cytoplasmic sequestering of transcription factor	4.515104e-3
GO:0033233	regulation of protein sumoylation	4.515104e-3
GO:0019408	dolichol biosynthetic process	4.622912e-3
GO:0016140	O-glycoside metabolic process	4.622912e-3
GO:0008156	negative regulation of DNA replication	4.664178e-3
GO:0007049	cell cycle	4.725343e-3
GO:0000819	sister chromatid segregation	4.726407e-3
GO:0048103	somatic stem cell division	4.740748e-3
GO:0034508	centromere complex assembly	4.783226e-3
GO:0045792	negative regulation of cell size	4.783226e-3
GO:0003192	mitral valve formation	4.783226e-3
GO:0006663	platelet activating factor biosynthetic process	4.861450e-3
GO:0007435	salivary gland morphogenesis	4.864346e-3
GO:0090009	primitive streak formation	4.872600e-3
GO:0042384	cilium assembly	4.913635e-3
GO:0031056	regulation of histone modification	4.917643e-3
GO:0009130	pyrimidine nucleoside monophosphate biosynthetic process	4.933532e-3
GO:0008054	cyclin catabolic process	4.935281e-3
GO:0046939	nucleotide phosphorylation	4.942983e-3
GO:0021794	thalamus development	4.942983e-3
GO:0060029	convergent extension involved in organogenesis	4.961763e-3
GO:0072488	ammonium transmembrane transport	5.064289e-3
GO:0072109	glomerular mesangium development	5.326509e-3
GO:0051301	cell division	5.352552e-3
GO:0060166	olfactory pit development	5.452196e-3
GO:0090102	cochlea development	5.506079e-3
GO:0009133	nucleoside diphosphate biosynthetic process	5.592808e-3
GO:0007141	male meiosis I	5.592808e-3
GO:0060591	chondroblast differentiation	5.616228e-3
GO:0034067	protein localization in Golgi apparatus	5.754221e-3
GO:0006188	IMP biosynthetic process	5.928940e-3
GO:0006913	nucleocytoplasmic transport	6.017100e-3
GO:0051383	kinetochore organization	6.035052e-3
GO:0042660	positive regulation of cell fate specification	6.035052e-3
GO:0001881	receptor recycling	6.035052e-3
GO:0000076	DNA replication checkpoint	6.035052e-3
GO:0051488	activation of anaphase-promoting complex activity	6.101382e-3
GO:0048853	forebrain morphogenesis	6.198176e-3
GO:0043583	ear development	6.274483e-3
GO:0040040	thermosensory behavior	6.293744e-3
GO:0009088	threonine biosynthetic process	6.293744e-3
GO:0002730	regulation of dendritic cell cytokine production	6.293744e-3
GO:0003195	tricuspid valve formation	6.521442e-3
GO:0006434	seryl-tRNA aminoacylation	6.551997e-3
GO:0070935	3'-UTR-mediated mRNA stabilization	6.551997e-3
GO:0010639	negative regulation of organelle organization	6.563637e-3
GO:0006396	RNA processing	6.571673e-3
GO:0030030	cell projection organization	6.642844e-3
GO:0042443	phenylethylamine metabolic process	6.661841e-3
GO:0070535	histone H2A K63-linked ubiquitination	6.661841e-3
GO:0016142	O-glycoside catabolic process	6.661841e-3
GO:0051642	centrosome localization	6.716878e-3
GO:0006892	post-Golgi vesicle-mediated transport	6.741930e-3
GO:0070925	organelle assembly	6.766621e-3
GO:0021797	forebrain anterior/posterior pattern specification	6.775653e-3
GO:0010972	negative regulation of G2/M transition of mitotic cell cycle	6.806484e-3
GO:0006013	mannose metabolic process	6.844530e-3
GO:0043923	positive regulation by host of viral transcription	6.857171e-3
GO:0060535	trachea cartilage morphogenesis	6.879739e-3
GO:0033235	positive regulation of protein sumoylation	6.879739e-3
GO:0006606	protein import into nucleus	6.888191e-3
GO:0061354	planar cell polarity pathway involved in pericardium morphogenesis	6.892092e-3
GO:0061350	planar cell polarity pathway involved in cardiac muscle tissue morphogenesis	6.892092e-3
GO:0061349	planar cell polarity pathway involved in cardiac right atrium morphogenesis	6.892092e-3
GO:0060210	metestrus	6.892092e-3
GO:0061347	planar cell polarity pathway involved in outflow tract morphogenesis	6.892092e-3
GO:0061348	planar cell polarity pathway involved in ventricular septum morphogenesis	6.892092e-3
GO:0035262	gonad morphogenesis	6.910970e-3
GO:0021985	neurohypophysis development	6.910970e-3
GO:0034314	Arp2/3 complex-mediated actin nucleation	6.910970e-3
GO:0090312	positive regulation of protein deacetylation	6.942165e-3
GO:0006807	nitrogen compound metabolic process	7.072999e-3
GO:0048562	embryonic organ morphogenesis	7.131898e-3
GO:0048384	retinoic acid receptor signaling pathway	7.157755e-3
GO:0048246	macrophage chemotaxis	7.180490e-3
GO:0003175	tricuspid valve development	7.180490e-3
GO:0010948	negative regulation of cell cycle process	7.414875e-3
GO:0009144	purine nucleoside triphosphate metabolic process	7.473223e-3
GO:0006220	pyrimidine nucleotide metabolic process	7.551187e-3
GO:0043046	DNA methylation involved in gamete generation	7.552921e-3
GO:0043491	protein kinase B signaling cascade	7.559163e-3
GO:0051881	regulation of mitochondrial membrane potential	7.567411e-3
GO:0016236	macroautophagy	7.570421e-3
GO:0031102	neuron projection regeneration	7.570421e-3
GO:0009620	response to fungus	7.725110e-3
GO:0000212	meiotic spindle organization	7.740776e-3
GO:0090161	Golgi ribbon formation	7.768084e-3
GO:2000384	negative regulation of ectoderm development	7.768084e-3
GO:0042058	regulation of epidermal growth factor receptor signaling pathway	7.772879e-3
GO:0007126	meiosis	7.829826e-3
GO:0060750	epithelial cell proliferation involved in mammary gland duct elongation	7.900772e-3
GO:0006749	glutathione metabolic process	7.922030e-3
GO:0051452	intracellular pH reduction	7.929472e-3
GO:0070370	cellular heat acclimation	7.945739e-3
GO:0043048	dolichyl monophosphate biosynthetic process	7.945739e-3
GO:0071279	cellular response to cobalt ion	7.945739e-3
GO:0090341	negative regulation of secretion of lysosomal enzymes	7.945739e-3
GO:0035852	horizontal cell localization	7.945739e-3
GO:2000768	positive regulation of nephron tubule epithelial cell differentiation	7.945739e-3
GO:0090188	negative regulation of pancreatic juice secretion	7.945739e-3
GO:0032077	positive regulation of deoxyribonuclease activity	7.945739e-3
GO:0014808	release of sequestered calcium ion into cytosol by sarcoplasmic reticulum	7.945739e-3
GO:0035849	nephric duct elongation	7.945739e-3
GO:0009794	regulation of mitotic cell cycle, embryonic	7.945739e-3
GO:0010637	negative regulation of mitochondrial fusion	7.945739e-3
GO:0035847	uterine epithelium development	7.945739e-3
GO:0035846	oviduct epithelium development	7.945739e-3
GO:0032802	low-density lipoprotein particle receptor catabolic process	7.945739e-3
GO:0030858	positive regulation of epithelial cell differentiation	7.987224e-3
GO:0031065	positive regulation of histone deacetylation	8.056435e-3
GO:0000045	autophagic vacuole assembly	8.154261e-3
GO:0051170	nuclear import	8.177958e-3
GO:0046131	pyrimidine ribonucleoside metabolic process	8.310147e-3
GO:0030031	cell projection assembly	8.312176e-3
GO:0072513	positive regulation of secondary heart field cardioblast proliferation	8.474558e-3
GO:0033238	regulation of cellular amine metabolic process	8.672362e-3
GO:0071108	protein K48-linked deubiquitination	8.782429e-3
GO:0060427	lung connective tissue development	8.791678e-3
GO:0048496	maintenance of organ identity	9.084093e-3
GO:0070507	regulation of microtubule cytoskeleton organization	9.117292e-3
GO:0034470	ncRNA processing	9.177607e-3
GO:0006828	manganese ion transport	9.192271e-3
GO:0009141	nucleoside triphosphate metabolic process	9.451036e-3
GO:0060762	regulation of branching involved in mammary gland duct morphogenesis	9.475806e-3
GO:0007064	mitotic sister chromatid cohesion	9.475806e-3
GO:0060340	positive regulation of type I interferon-mediated signaling pathway	9.619963e-3
GO:0046548	retinal rod cell development	9.619963e-3
GO:0006412	translation	9.820385e-3
GO:0035026	leading edge cell differentiation	9.828339e-3
GO:0060540	diaphragm morphogenesis	9.828339e-3
GO:0060464	lung lobe formation	9.828339e-3
GO:0000720	pyrimidine dimer repair by nucleotide-excision repair	9.828339e-3
GO:0006189	'de novo' IMP biosynthetic process	9.828339e-3
GO:0030221	basophil differentiation	9.828339e-3
GO:0006208	pyrimidine base catabolic process	9.930234e-3
GO:0002741	positive regulation of cytokine secretion involved in immune response	9.993623e-3
GO:0060648	mammary gland bud morphogenesis	1.004821e-2
GO:0021506	anterior neuropore closure	1.004821e-2
GO:0006886	intracellular protein transport	1.023752e-2
GO:0033522	histone H2A ubiquitination	1.026115e-2
GO:0009234	menaquinone biosynthetic process	1.030185e-2
GO:0033314	mitotic cell cycle DNA replication checkpoint	1.030185e-2
GO:0048332	mesoderm morphogenesis	1.035638e-2
GO:0007028	cytoplasm organization	1.039233e-2
GO:0035264	multicellular organism growth	1.039870e-2
GO:0048340	paraxial mesoderm morphogenesis	1.054181e-2
GO:0017183	peptidyl-diphthamide biosynthetic process from peptidyl-histidine	1.065465e-2
GO:0015747	urate transport	1.065465e-2
GO:0014707	branchiomeric skeletal muscle development	1.065465e-2
GO:0002175	protein localization to paranode region of axon	1.065465e-2
GO:0042178	xenobiotic catabolic process	1.066127e-2
GO:0045351	type I interferon biosynthetic process	1.075862e-2
GO:0071985	multivesicular body sorting pathway	1.078057e-2
GO:0000415	negative regulation of histone H3-K36 methylation	1.078057e-2
GO:0016139	glycoside catabolic process	1.078057e-2
GO:0014909	smooth muscle cell migration	1.078061e-2
GO:0007412	axon target recognition	1.078061e-2
GO:0006398	histone mRNA 3'-end processing	1.078061e-2
GO:0030307	positive regulation of cell growth	1.083241e-2
GO:0060484	lung-associated mesenchyme development	1.084426e-2
GO:0051169	nuclear transport	1.104769e-2
GO:0034661	ncRNA catabolic process	1.109833e-2
GO:0048678	response to axon injury	1.138742e-2
GO:0060026	convergent extension	1.140403e-2
GO:0090045	positive regulation of deacetylase activity	1.146200e-2
GO:0006043	glucosamine catabolic process	1.146200e-2
GO:0000053	argininosuccinate metabolic process	1.152129e-2
GO:0009124	nucleoside monophosphate biosynthetic process	1.159255e-2
GO:0032467	positive regulation of cytokinesis	1.177985e-2
GO:0007223	Wnt receptor signaling pathway, calcium modulating pathway	1.177985e-2
GO:0006287	base-excision repair, gap-filling	1.178926e-2
GO:0001843	neural tube closure	1.184485e-2
GO:0072521	purine-containing compound metabolic process	1.184585e-2
GO:0060606	tube closure	1.203716e-2
GO:0072199	regulation of mesenchymal cell proliferation involved in ureter development	1.230892e-2
GO:0018283	iron incorporation into metallo-sulfur cluster	1.241690e-2
GO:0010991	negative regulation of SMAD protein complex assembly	1.241690e-2
GO:0038007	netrin-activated signaling pathway	1.248558e-2
GO:0071421	manganese ion transmembrane transport	1.273214e-2
GO:0060482	lobar bronchus development	1.273214e-2
GO:0045618	positive regulation of keratinocyte differentiation	1.273214e-2
GO:0046031	ADP metabolic process	1.284897e-2
GO:0006221	pyrimidine nucleotide biosynthetic process	1.306796e-2
GO:0071243	cellular response to arsenic-containing substance	1.350122e-2
GO:2000108	positive regulation of leukocyte apoptosis	1.352535e-2
GO:0016070	RNA metabolic process	1.372449e-2
GO:0032717	negative regulation of interleukin-8 production	1.391174e-2
GO:0090303	positive regulation of wound healing	1.391174e-2
GO:0030182	neuron differentiation	1.394706e-2
GO:0051302	regulation of cell division	1.396701e-2
GO:0071394	cellular response to testosterone stimulus	1.419947e-2
GO:0047497	mitochondrion transport along microtubule	1.423007e-2
GO:0090304	nucleic acid metabolic process	1.433874e-2
GO:0060602	branch elongation of an epithelium	1.445838e-2
GO:0072012	glomerulus vasculature development	1.456388e-2
GO:0045080	positive regulation of chemokine biosynthetic process	1.492793e-2
GO:0014812	muscle cell migration	1.492793e-2
GO:0048025	negative regulation of nuclear mRNA splicing, via spliceosome	1.495391e-2
GO:0000060	protein import into nucleus, translocation	1.509634e-2
GO:0060523	prostate epithelial cord elongation	1.521075e-2
GO:0060737	prostate gland morphogenetic growth	1.526576e-2
GO:0002066	columnar/cuboidal epithelial cell development	1.526576e-2
GO:0032364	oxygen homeostasis	1.546443e-2
GO:0000042	protein targeting to Golgi	1.546443e-2
GO:0040023	establishment of nucleus localization	1.553762e-2
GO:0021873	forebrain neuroblast division	1.564656e-2
GO:0061099	negative regulation of protein tyrosine kinase activity	1.591458e-2
GO:0042424	catecholamine catabolic process	1.602043e-2
GO:0035229	positive regulation of glutamate-cysteine ligase activity	1.605909e-2
GO:0034622	cellular macromolecular complex assembly	1.612638e-2
GO:0055099	response to high density lipoprotein particle stimulus	1.641957e-2
GO:0001306	age-dependent response to oxidative stress	1.641957e-2
GO:2000653	regulation of genetic imprinting	1.682064e-2
GO:0072428	signal transduction involved in intra-S DNA damage checkpoint	1.682064e-2
GO:0046604	positive regulation of mitotic centrosome separation	1.682064e-2
GO:0045872	positive regulation of rhodopsin gene expression	1.682064e-2
GO:0031128	developmental induction	1.687211e-2
GO:0007052	mitotic spindle organization	1.693856e-2
GO:0034142	toll-like receptor 4 signaling pathway	1.706004e-2
GO:0043415	positive regulation of skeletal muscle tissue regeneration	1.706004e-2
GO:0002065	columnar/cuboidal epithelial cell differentiation	1.718703e-2
GO:0050982	detection of mechanical stimulus	1.723925e-2
GO:0021515	cell differentiation in spinal cord	1.742038e-2
GO:0048854	brain morphogenesis	1.773250e-2
GO:0090037	positive regulation of protein kinase C signaling cascade	1.773791e-2
GO:0045851	pH reduction	1.776231e-2
GO:0045963	negative regulation of dopamine metabolic process	1.783728e-2
GO:0046952	ketone body catabolic process	1.783728e-2
GO:0035419	activation of MAPK activity involved in innate immune response	1.783728e-2
GO:0050668	positive regulation of homocysteine metabolic process	1.783728e-2
GO:0006120	mitochondrial electron transport, NADH to ubiquinone	1.783728e-2