Novel motif:6

name:	motif6_AAGACT

Association to promoter expression in human samples<b>Summary:</b>Significance of the correlation with CAGE expression, human <br><b>Analyst:</b> Michiel de Hoon<br><br>link to source dataset <br>data

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Association to promoter expression in mouse samples <b>Summary:</b>Significance of the correlation with CAGE expression, mouse <br><b>Analyst:</b> Michiel de Hoon<br><br>link to source dataset <br>data

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GREAT analysis results for human <b>Summary:</b>Genomic Enrichment of Annotations Tool (GREAT, Nat Biotechnol. 2010 May;28(5):495-501) is used to identify, both in human and in mouse, the gene ontology terms of biological processes enriched given the predicted TFBSs, and evaluated the overlap in the top-500 gene ontology terms between human and mouse. For each novel motif, the P value for the overlap was then evaluated by calculating its relative rank with respect to this background distribution.<br>Analyst: Michiel de Hoon<br><br>link to source dataset <br>data

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GO ID	GO Term	p-value
GO:0006950	response to stress	3.013363e-32
GO:0009611	response to wounding	9.956981e-30
GO:0050896	response to stimulus	4.222681e-29
GO:0032501	multicellular organismal process	2.844920e-24
GO:0030168	platelet activation	4.207682e-21
GO:0032502	developmental process	6.732643e-21
GO:0009987	cellular process	6.811661e-21
GO:0050794	regulation of cellular process	7.110139e-21
GO:0042060	wound healing	1.349589e-20
GO:0051716	cellular response to stimulus	1.421063e-20
GO:0065007	biological regulation	6.229882e-20
GO:0048513	organ development	1.043606e-19
GO:0050789	regulation of biological process	1.263640e-19
GO:0002576	platelet degranulation	9.719479e-19
GO:0048856	anatomical structure development	1.131207e-18
GO:0065008	regulation of biological quality	1.689314e-18
GO:0001775	cell activation	2.755466e-18
GO:0055013	cardiac muscle cell development	6.167854e-18
GO:0006954	inflammatory response	1.685224e-17
GO:0050793	regulation of developmental process	2.980133e-17
GO:0009888	tissue development	3.262791e-17
GO:0051179	localization	6.269522e-17
GO:0006952	defense response	6.384939e-17
GO:0042221	response to chemical stimulus	6.501779e-17
GO:0007165	signal transduction	8.735498e-17
GO:0051234	establishment of localization	9.863847e-17
GO:0051240	positive regulation of multicellular organismal process	1.033581e-16
GO:0006810	transport	1.130987e-16
GO:0007154	cell communication	2.223716e-16
GO:0002376	immune system process	2.232505e-16
GO:0048731	system development	4.043001e-16
GO:0055003	cardiac myofibril assembly	5.340179e-16
GO:0032101	regulation of response to external stimulus	3.864834e-15
GO:0043170	macromolecule metabolic process	4.144877e-15
GO:0007275	multicellular organismal development	5.637486e-15
GO:0051239	regulation of multicellular organismal process	7.445602e-15
GO:0032879	regulation of localization	1.109134e-14
GO:0007525	somatic muscle development	1.150811e-14
GO:0007596	blood coagulation	1.212150e-14
GO:0023052	signaling	1.623856e-14
GO:0048518	positive regulation of biological process	1.868397e-14
GO:0032940	secretion by cell	1.882794e-14
GO:0048769	sarcomerogenesis	2.010253e-14
GO:0007599	hemostasis	2.195467e-14
GO:0006955	immune response	2.537771e-14
GO:0051094	positive regulation of developmental process	2.603630e-14
GO:0042127	regulation of cell proliferation	2.775101e-14
GO:2000026	regulation of multicellular organismal development	4.693327e-14
GO:0003006	developmental process involved in reproduction	6.801638e-14
GO:0007076	mitotic chromosome condensation	7.497848e-14
GO:0032103	positive regulation of response to external stimulus	8.993297e-14
GO:0030240	skeletal muscle thin filament assembly	1.154332e-13
GO:0042493	response to drug	1.357903e-13
GO:0008152	metabolic process	2.149723e-13
GO:0018149	peptide cross-linking	2.343818e-13
GO:0072358	cardiovascular system development	4.022462e-13
GO:0022414	reproductive process	4.627991e-13
GO:0010033	response to organic substance	4.842128e-13
GO:0046903	secretion	5.028101e-13
GO:0044260	cellular macromolecule metabolic process	6.417094e-13
GO:0000003	reproduction	6.447467e-13
GO:0006928	cellular component movement	8.090050e-13
GO:0007166	cell surface receptor linked signaling pathway	8.351183e-13
GO:0044238	primary metabolic process	9.561937e-13
GO:0048583	regulation of response to stimulus	9.655470e-13
GO:0048522	positive regulation of cellular process	2.217614e-12
GO:0003008	system process	2.447932e-12
GO:0048468	cell development	2.476131e-12
GO:0071103	DNA conformation change	2.803638e-12
GO:0006464	protein modification process	3.023721e-12
GO:0019538	protein metabolic process	3.100228e-12
GO:0050878	regulation of body fluid levels	3.223126e-12
GO:0048523	negative regulation of cellular process	3.337439e-12
GO:0030261	chromosome condensation	3.538423e-12
GO:0048519	negative regulation of biological process	3.547689e-12
GO:0010035	response to inorganic substance	4.076871e-12
GO:0043067	regulation of programmed cell death	5.359353e-12
GO:0048520	positive regulation of behavior	6.707999e-12
GO:0045765	regulation of angiogenesis	7.188307e-12
GO:0010574	regulation of vascular endothelial growth factor production	7.343914e-12
GO:0042325	regulation of phosphorylation	8.030978e-12
GO:0042981	regulation of apoptosis	9.413985e-12
GO:0010941	regulation of cell death	9.966383e-12
GO:0051606	detection of stimulus	1.377174e-11
GO:0019220	regulation of phosphate metabolic process	2.052516e-11
GO:0060255	regulation of macromolecule metabolic process	2.062278e-11
GO:0055007	cardiac muscle cell differentiation	2.129579e-11
GO:0019222	regulation of metabolic process	2.148305e-11
GO:0009893	positive regulation of metabolic process	2.883221e-11
GO:0043412	macromolecule modification	3.077724e-11
GO:0050795	regulation of behavior	3.134533e-11
GO:0045595	regulation of cell differentiation	3.616695e-11
GO:0001819	positive regulation of cytokine production	4.869476e-11
GO:0051093	negative regulation of developmental process	4.977785e-11
GO:0051641	cellular localization	5.419325e-11
GO:0043069	negative regulation of programmed cell death	5.482331e-11
GO:0048646	anatomical structure formation involved in morphogenesis	6.377771e-11
GO:0048869	cellular developmental process	6.480324e-11
GO:0051649	establishment of localization in cell	7.839392e-11
GO:0030241	skeletal muscle myosin thick filament assembly	9.994243e-11
GO:0050776	regulation of immune response	1.122209e-10
GO:0043066	negative regulation of apoptosis	1.196909e-10
GO:0050727	regulation of inflammatory response	1.217144e-10
GO:0031323	regulation of cellular metabolic process	1.357819e-10
GO:0048608	reproductive structure development	1.371689e-10
GO:0030049	muscle filament sliding	1.427338e-10
GO:0060548	negative regulation of cell death	1.452175e-10
GO:0000819	sister chromatid segregation	2.095297e-10
GO:0031394	positive regulation of prostaglandin biosynthetic process	2.211368e-10
GO:0007049	cell cycle	2.391950e-10
GO:0010604	positive regulation of macromolecule metabolic process	2.415625e-10
GO:0040012	regulation of locomotion	2.668930e-10
GO:0032496	response to lipopolysaccharide	2.856431e-10
GO:0090304	nucleic acid metabolic process	2.872949e-10
GO:0070252	actin-mediated cell contraction	2.910504e-10
GO:0006887	exocytosis	2.985787e-10
GO:0044267	cellular protein metabolic process	3.008047e-10
GO:0048739	cardiac muscle fiber development	3.659496e-10
GO:0030154	cell differentiation	3.710457e-10
GO:0006323	DNA packaging	3.952663e-10
GO:0030334	regulation of cell migration	3.984424e-10
GO:0060324	face development	4.176197e-10
GO:0007155	cell adhesion	4.966382e-10
GO:0032268	regulation of cellular protein metabolic process	5.282211e-10
GO:0002683	negative regulation of immune system process	5.605155e-10
GO:0045597	positive regulation of cell differentiation	5.746541e-10
GO:0048585	negative regulation of response to stimulus	5.918534e-10
GO:0000070	mitotic sister chromatid segregation	6.031728e-10
GO:0044237	cellular metabolic process	6.246785e-10
GO:0051592	response to calcium ion	6.875683e-10
GO:0051049	regulation of transport	7.099982e-10
GO:0016192	vesicle-mediated transport	7.977692e-10
GO:0040017	positive regulation of locomotion	9.214063e-10
GO:0045214	sarcomere organization	1.169370e-9
GO:0045087	innate immune response	1.226017e-9
GO:0048609	multicellular organismal reproductive process	1.278402e-9
GO:0002237	response to molecule of bacterial origin	1.291972e-9
GO:0035051	cardiac cell differentiation	1.391509e-9
GO:0014866	skeletal myofibril assembly	1.496751e-9
GO:0033036	macromolecule localization	1.709313e-9
GO:0030728	ovulation	1.713629e-9
GO:0051050	positive regulation of transport	1.870047e-9
GO:0050864	regulation of B cell activation	2.216380e-9
GO:0043032	positive regulation of macrophage activation	2.273904e-9
GO:2000145	regulation of cell motility	2.363685e-9
GO:0007067	mitosis	2.472504e-9
GO:0023057	negative regulation of signaling	2.630693e-9
GO:0022402	cell cycle process	2.647679e-9
GO:0030048	actin filament-based movement	2.743106e-9
GO:0048644	muscle organ morphogenesis	2.926181e-9
GO:0007186	G-protein coupled receptor protein signaling pathway	2.947852e-9
GO:0010648	negative regulation of cell communication	2.981302e-9
GO:0016525	negative regulation of angiogenesis	3.066529e-9
GO:0001932	regulation of protein phosphorylation	3.151895e-9
GO:0032735	positive regulation of interleukin-12 production	3.341665e-9
GO:0030239	myofibril assembly	3.695187e-9
GO:0008585	female gonad development	3.752156e-9
GO:0043615	astrocyte cell migration	3.940346e-9
GO:0000087	M phase of mitotic cell cycle	3.963731e-9
GO:0050869	negative regulation of B cell activation	4.249829e-9
GO:0002690	positive regulation of leukocyte chemotaxis	4.987932e-9
GO:0008406	gonad development	5.069303e-9
GO:0031099	regeneration	5.134554e-9
GO:0050921	positive regulation of chemotaxis	5.261837e-9
GO:0050865	regulation of cell activation	5.284469e-9
GO:0060322	head development	5.412673e-9
GO:0048285	organelle fission	5.723050e-9
GO:0046660	female sex differentiation	6.733744e-9
GO:0051770	positive regulation of nitric-oxide synthase biosynthetic process	6.771477e-9
GO:0051409	response to nitrosative stress	7.082919e-9
GO:0007517	muscle organ development	7.756516e-9
GO:0031100	organ regeneration	7.852779e-9
GO:0002688	regulation of leukocyte chemotaxis	8.505618e-9
GO:0045723	positive regulation of fatty acid biosynthetic process	8.813888e-9
GO:0050920	regulation of chemotaxis	9.021996e-9
GO:0046545	development of primary female sexual characteristics	9.213053e-9
GO:0040008	regulation of growth	9.376450e-9
GO:0051769	regulation of nitric-oxide synthase biosynthetic process	9.534823e-9
GO:0008285	negative regulation of cell proliferation	1.103224e-8
GO:0048511	rhythmic process	1.115439e-8
GO:0051704	multi-organism process	1.116464e-8
GO:0010468	regulation of gene expression	1.128812e-8
GO:0055001	muscle cell development	1.153693e-8
GO:0031032	actomyosin structure organization	1.210557e-8
GO:0007507	heart development	1.229838e-8
GO:0032026	response to magnesium ion	1.570782e-8
GO:0051270	regulation of cellular component movement	1.583744e-8
GO:0010758	regulation of macrophage chemotaxis	1.619844e-8
GO:0021854	hypothalamus development	1.702469e-8
GO:0090265	positive regulation of immune complex clearance by monocytes and macrophages	1.830767e-8
GO:0007548	sex differentiation	1.926952e-8
GO:0050778	positive regulation of immune response	2.329641e-8
GO:0051246	regulation of protein metabolic process	2.354371e-8
GO:0048771	tissue remodeling	2.425650e-8
GO:0009628	response to abiotic stimulus	2.565893e-8
GO:0002673	regulation of acute inflammatory response	2.661596e-8
GO:0002684	positive regulation of immune system process	2.707553e-8
GO:0002694	regulation of leukocyte activation	2.830912e-8
GO:0030888	regulation of B cell proliferation	2.936575e-8
GO:0042180	cellular ketone metabolic process	2.951212e-8
GO:0001817	regulation of cytokine production	3.106840e-8
GO:0051707	response to other organism	3.144463e-8
GO:0002687	positive regulation of leukocyte migration	3.321318e-8
GO:0045137	development of primary sexual characteristics	3.463006e-8
GO:0009889	regulation of biosynthetic process	3.511991e-8
GO:0048584	positive regulation of response to stimulus	3.593225e-8
GO:0003012	muscle system process	3.932031e-8
GO:0000255	allantoin metabolic process	4.143049e-8
GO:0045346	regulation of MHC class II biosynthetic process	4.644054e-8
GO:0080090	regulation of primary metabolic process	4.730703e-8
GO:0006807	nitrogen compound metabolic process	5.086979e-8
GO:0055008	cardiac muscle tissue morphogenesis	5.807326e-8
GO:0060452	positive regulation of cardiac muscle contraction	5.944097e-8
GO:0032317	regulation of Rap GTPase activity	6.327876e-8
GO:0009306	protein secretion	6.773814e-8
GO:0042554	superoxide anion generation	6.782686e-8
GO:0071310	cellular response to organic substance	6.808734e-8
GO:0030335	positive regulation of cell migration	6.848908e-8
GO:0009968	negative regulation of signal transduction	7.986079e-8
GO:0002685	regulation of leukocyte migration	8.482639e-8
GO:0071622	regulation of granulocyte chemotaxis	8.750593e-8
GO:0045766	positive regulation of angiogenesis	9.062970e-8
GO:2000147	positive regulation of cell motility	9.091285e-8
GO:0031325	positive regulation of cellular metabolic process	9.459361e-8
GO:2000379	positive regulation of reactive oxygen species metabolic process	9.653906e-8
GO:0050729	positive regulation of inflammatory response	9.674567e-8
GO:0030595	leukocyte chemotaxis	9.699882e-8
GO:0070887	cellular response to chemical stimulus	1.075112e-7
GO:0000278	mitotic cell cycle	1.107201e-7
GO:0048738	cardiac muscle tissue development	1.146737e-7
GO:0060415	muscle tissue morphogenesis	1.158908e-7
GO:0009617	response to bacterium	1.179737e-7
GO:0008284	positive regulation of cell proliferation	1.188129e-7
GO:0010038	response to metal ion	1.199340e-7
GO:2001021	negative regulation of response to DNA damage stimulus	1.210945e-7
GO:0048066	developmental pigmentation	1.218163e-7
GO:0022602	ovulation cycle process	1.298034e-7
GO:0035684	helper T cell extravasation	1.336778e-7
GO:0009581	detection of external stimulus	1.363257e-7
GO:0032728	positive regulation of interferon-beta production	1.425924e-7
GO:0010556	regulation of macromolecule biosynthetic process	1.448208e-7
GO:0031399	regulation of protein modification process	1.592708e-7
GO:0009891	positive regulation of biosynthetic process	1.662074e-7
GO:0009653	anatomical structure morphogenesis	1.843077e-7
GO:0042535	positive regulation of tumor necrosis factor biosynthetic process	1.898083e-7
GO:0006911	phagocytosis, engulfment	1.950753e-7
GO:0031349	positive regulation of defense response	1.992474e-7
GO:0071222	cellular response to lipopolysaccharide	2.007713e-7
GO:0034641	cellular nitrogen compound metabolic process	2.125507e-7
GO:0006259	DNA metabolic process	2.165520e-7
GO:0055098	response to low-density lipoprotein particle stimulus	2.213328e-7
GO:0050867	positive regulation of cell activation	2.313502e-7
GO:0010575	positive regulation vascular endothelial growth factor production	2.338313e-7
GO:0042698	ovulation cycle	2.369269e-7
GO:0033554	cellular response to stress	2.414513e-7
GO:0009607	response to biotic stimulus	2.438226e-7
GO:0019752	carboxylic acid metabolic process	2.480491e-7
GO:0060740	prostate gland epithelium morphogenesis	2.543741e-7
GO:0010759	positive regulation of macrophage chemotaxis	2.700383e-7
GO:0048870	cell motility	2.714237e-7
GO:0034059	response to anoxia	3.021332e-7
GO:0000165	MAPKKK cascade	3.112645e-7
GO:0001655	urogenital system development	3.175010e-7
GO:0061008	hepaticobiliary system development	3.222474e-7
GO:0055002	striated muscle cell development	3.267339e-7
GO:0032479	regulation of type I interferon production	3.305192e-7
GO:0045091	regulation of retroviral genome replication	3.321432e-7
GO:0048729	tissue morphogenesis	3.375974e-7
GO:0051272	positive regulation of cellular component movement	3.736308e-7
GO:0071219	cellular response to molecule of bacterial origin	3.985108e-7
GO:0006082	organic acid metabolic process	4.246888e-7
GO:0045740	positive regulation of DNA replication	4.348589e-7
GO:0070663	regulation of leukocyte proliferation	4.363052e-7
GO:0031326	regulation of cellular biosynthetic process	4.583259e-7
GO:0060537	muscle tissue development	4.621939e-7
GO:0032854	positive regulation of Rap GTPase activity	4.857530e-7
GO:0071840	cellular component organization or biogenesis	5.138102e-7
GO:0010955	negative regulation of protein processing	5.145654e-7
GO:0010754	negative regulation of cGMP-mediated signaling	5.184666e-7
GO:0043652	engulfment of apoptotic cell	5.184666e-7
GO:0010751	negative regulation of nitric oxide mediated signal transduction	5.184666e-7
GO:0002605	negative regulation of dendritic cell antigen processing and presentation	5.184666e-7
GO:0002581	negative regulation of antigen processing and presentation of peptide or polysaccharide antigen via MHC class II	5.184666e-7
GO:0043518	negative regulation of DNA damage response, signal transduction by p53 class mediator	5.186198e-7
GO:0010608	posttranscriptional regulation of gene expression	5.263140e-7
GO:0006916	anti-apoptosis	5.283838e-7
GO:0032642	regulation of chemokine production	5.456031e-7
GO:0050953	sensory perception of light stimulus	5.584634e-7
GO:0060512	prostate gland morphogenesis	5.596600e-7
GO:0001889	liver development	5.884804e-7
GO:0016477	cell migration	6.417797e-7
GO:0071216	cellular response to biotic stimulus	6.456350e-7
GO:0042327	positive regulation of phosphorylation	6.602968e-7
GO:0008104	protein localization	6.667134e-7
GO:0070668	positive regulation of mast cell proliferation	6.783079e-7
GO:0008206	bile acid metabolic process	6.883708e-7
GO:0034605	cellular response to heat	7.033615e-7
GO:0045859	regulation of protein kinase activity	7.091053e-7
GO:0002674	negative regulation of acute inflammatory response	7.115912e-7
GO:0071675	regulation of mononuclear cell migration	7.189716e-7
GO:0045596	negative regulation of cell differentiation	7.789502e-7
GO:0032655	regulation of interleukin-12 production	7.865668e-7
GO:0050931	pigment cell differentiation	7.937881e-7
GO:0040036	regulation of fibroblast growth factor receptor signaling pathway	8.073263e-7
GO:0061061	muscle structure development	8.215070e-7
GO:0007600	sensory perception	8.629864e-7
GO:0010165	response to X-ray	9.479143e-7
GO:0014823	response to activity	9.616782e-7
GO:2000112	regulation of cellular macromolecule biosynthetic process	1.063888e-6
GO:0034694	response to prostaglandin stimulus	1.065754e-6
GO:0007601	visual perception	1.077834e-6
GO:0032481	positive regulation of type I interferon production	1.089703e-6
GO:0042035	regulation of cytokine biosynthetic process	1.101898e-6
GO:0002520	immune system development	1.139193e-6
GO:0002682	regulation of immune system process	1.203898e-6
GO:0050900	leukocyte migration	1.208627e-6
GO:0030889	negative regulation of B cell proliferation	1.220115e-6
GO:0080134	regulation of response to stress	1.235588e-6
GO:0006936	muscle contraction	1.235797e-6
GO:0002696	positive regulation of leukocyte activation	1.271734e-6
GO:0023051	regulation of signaling	1.308560e-6
GO:0010646	regulation of cell communication	1.312773e-6
GO:0043405	regulation of MAP kinase activity	1.330431e-6
GO:0016043	cellular component organization	1.359762e-6
GO:0006941	striated muscle contraction	1.391524e-6
GO:0014706	striated muscle tissue development	1.412653e-6
GO:0060137	maternal process involved in parturition	1.418583e-6
GO:0070365	hepatocyte differentiation	1.450677e-6
GO:0010757	negative regulation of plasminogen activation	1.458853e-6
GO:0042663	regulation of endodermal cell fate specification	1.495010e-6
GO:0008347	glial cell migration	1.499257e-6
GO:0015031	protein transport	1.524721e-6
GO:0030029	actin filament-based process	1.531943e-6
GO:0034097	response to cytokine stimulus	1.582187e-6
GO:0006629	lipid metabolic process	1.593094e-6
GO:0043536	positive regulation of blood vessel endothelial cell migration	1.641685e-6
GO:0008584	male gonad development	1.692812e-6
GO:0042438	melanin biosynthetic process	1.725345e-6
GO:0045937	positive regulation of phosphate metabolic process	1.789254e-6
GO:0090066	regulation of anatomical structure size	1.974678e-6
GO:0043030	regulation of macrophage activation	1.982587e-6
GO:0002246	wound healing involved in inflammatory response	2.007098e-6
GO:0045347	negative regulation of MHC class II biosynthetic process	2.018107e-6
GO:0090362	positive regulation of platelet-derived growth factor production	2.018970e-6
GO:0090336	positive regulation of brown fat cell differentiation	2.018970e-6
GO:0090271	positive regulation of fibroblast growth factor production	2.018970e-6
GO:0071985	multivesicular body sorting pathway	2.091692e-6
GO:0043549	regulation of kinase activity	2.113091e-6
GO:0031644	regulation of neurological system process	2.118217e-6
GO:0006930	substrate-dependent cell migration, cell extension	2.182561e-6
GO:0007292	female gamete generation	2.190551e-6
GO:0008207	C21-steroid hormone metabolic process	2.223166e-6
GO:0010557	positive regulation of macromolecule biosynthetic process	2.241464e-6
GO:0012501	programmed cell death	2.398742e-6
GO:0019428	allantoin biosynthetic process	2.398783e-6
GO:0019915	lipid storage	2.416791e-6
GO:0006796	phosphate-containing compound metabolic process	2.677096e-6
GO:0022403	cell cycle phase	2.683790e-6
GO:0010594	regulation of endothelial cell migration	2.828720e-6
GO:0006508	proteolysis	2.851664e-6
GO:0010942	positive regulation of cell death	2.889632e-6
GO:0048638	regulation of developmental growth	2.902873e-6
GO:0043516	regulation of DNA damage response, signal transduction by p53 class mediator	2.970150e-6
GO:0009966	regulation of signal transduction	3.019084e-6
GO:0043068	positive regulation of programmed cell death	3.112666e-6
GO:0050906	detection of stimulus involved in sensory perception	3.157824e-6
GO:0071634	regulation of transforming growth factor beta production	3.207387e-6
GO:0045076	regulation of interleukin-2 biosynthetic process	3.300032e-6
GO:0035589	G-protein coupled purinergic nucleotide receptor signaling pathway	3.308369e-6
GO:0001937	negative regulation of endothelial cell proliferation	3.395234e-6
GO:0030001	metal ion transport	3.431242e-6
GO:0045069	regulation of viral genome replication	3.435130e-6
GO:0031646	positive regulation of neurological system process	3.496240e-6
GO:0032760	positive regulation of tumor necrosis factor production	3.546480e-6
GO:0009058	biosynthetic process	3.548428e-6
GO:0007276	gamete generation	3.587828e-6
GO:0042264	peptidyl-aspartic acid hydroxylation	3.598621e-6
GO:0051338	regulation of transferase activity	3.812799e-6
GO:0032680	regulation of tumor necrosis factor production	3.875984e-6
GO:0019725	cellular homeostasis	3.877422e-6
GO:0007059	chromosome segregation	3.980784e-6
GO:0042100	B cell proliferation	4.043448e-6
GO:0009266	response to temperature stimulus	4.151457e-6
GO:0009408	response to heat	4.258264e-6
GO:0043603	cellular amide metabolic process	4.261249e-6
GO:0031328	positive regulation of cellular biosynthetic process	4.360737e-6
GO:0043065	positive regulation of apoptosis	4.456720e-6
GO:0071636	positive regulation of transforming growth factor beta production	4.476351e-6
GO:0032989	cellular component morphogenesis	4.590682e-6
GO:0030518	steroid hormone receptor signaling pathway	4.612698e-6
GO:0045742	positive regulation of epidermal growth factor receptor signaling pathway	4.791653e-6
GO:0051971	positive regulation of transmission of nerve impulse	4.838694e-6
GO:0051276	chromosome organization	4.862822e-6
GO:0048747	muscle fiber development	4.922787e-6
GO:0006811	ion transport	4.990712e-6
GO:0071726	cellular response to diacyl bacterial lipopeptide	4.992680e-6
GO:0042496	detection of diacyl bacterial lipopeptide	4.992680e-6
GO:0030098	lymphocyte differentiation	5.057902e-6
GO:0061039	ovum-producing ovary development	5.058400e-6
GO:0090270	regulation of fibroblast growth factor production	5.078017e-6
GO:0048534	hemopoietic or lymphoid organ development	5.239775e-6
GO:0032227	negative regulation of synaptic transmission, dopaminergic	5.275295e-6
GO:0032648	regulation of interferon-beta production	5.505248e-6
GO:0022603	regulation of anatomical structure morphogenesis	5.681097e-6
GO:0046677	response to antibiotic	5.819520e-6
GO:0001936	regulation of endothelial cell proliferation	5.895749e-6
GO:0002544	chronic inflammatory response	5.988971e-6
GO:0045921	positive regulation of exocytosis	6.116304e-6
GO:0030832	regulation of actin filament length	6.189476e-6
GO:0051171	regulation of nitrogen compound metabolic process	6.280608e-6
GO:0030318	melanocyte differentiation	6.283666e-6
GO:0042448	progesterone metabolic process	6.293731e-6
GO:0071223	cellular response to lipoteichoic acid	6.502197e-6
GO:0010755	regulation of plasminogen activation	6.515579e-6
GO:0010595	positive regulation of endothelial cell migration	6.583490e-6
GO:0008283	cell proliferation	6.684802e-6
GO:0016337	cell-cell adhesion	6.998358e-6
GO:0006139	nucleobase-containing compound metabolic process	7.000775e-6
GO:0030097	hemopoiesis	7.073146e-6
GO:0032570	response to progesterone stimulus	7.082463e-6
GO:0034754	cellular hormone metabolic process	7.352223e-6
GO:0032741	positive regulation of interleukin-18 production	7.461005e-6
GO:0007530	sex determination	7.527288e-6
GO:0009605	response to external stimulus	7.629093e-6
GO:0010212	response to ionizing radiation	7.744886e-6
GO:0006275	regulation of DNA replication	7.885738e-6
GO:0019219	regulation of nucleobase-containing compound metabolic process	7.918079e-6
GO:0071345	cellular response to cytokine stimulus	7.936269e-6
GO:0043535	regulation of blood vessel endothelial cell migration	8.194840e-6
GO:0048863	stem cell differentiation	8.272535e-6
GO:0051895	negative regulation of focal adhesion assembly	8.288633e-6
GO:0001547	antral ovarian follicle growth	8.346424e-6
GO:0006417	regulation of translation	8.506240e-6
GO:0015721	bile acid and bile salt transport	8.582459e-6
GO:0016339	calcium-dependent cell-cell adhesion	8.815690e-6
GO:0008202	steroid metabolic process	9.246317e-6
GO:0048545	response to steroid hormone stimulus	9.613854e-6
GO:0043473	pigmentation	9.798580e-6
GO:0009593	detection of chemical stimulus	9.935805e-6
GO:0046219	indolalkylamine biosynthetic process	1.008007e-5
GO:0045086	positive regulation of interleukin-2 biosynthetic process	1.008642e-5
GO:0048240	sperm capacitation	1.010714e-5
GO:0006582	melanin metabolic process	1.017252e-5
GO:0042534	regulation of tumor necrosis factor biosynthetic process	1.025200e-5
GO:0055082	cellular chemical homeostasis	1.030816e-5
GO:0045989	positive regulation of striated muscle contraction	1.041671e-5
GO:0051047	positive regulation of secretion	1.090223e-5
GO:0019953	sexual reproduction	1.090443e-5
GO:0010715	regulation of extracellular matrix disassembly	1.152734e-5
GO:0030259	lipid glycosylation	1.188925e-5
GO:0007281	germ cell development	1.192062e-5
GO:0002312	B cell activation involved in immune response	1.231134e-5
GO:0006338	chromatin remodeling	1.268018e-5
GO:0000279	M phase	1.297900e-5
GO:0007622	rhythmic behavior	1.316292e-5
GO:0072678	T cell migration	1.318215e-5
GO:0031645	negative regulation of neurological system process	1.351895e-5
GO:0051247	positive regulation of protein metabolic process	1.372205e-5
GO:0034695	response to prostaglandin E stimulus	1.377293e-5
GO:0044249	cellular biosynthetic process	1.391581e-5
GO:0070374	positive regulation of ERK1 and ERK2 cascade	1.402266e-5
GO:0060284	regulation of cell development	1.450894e-5
GO:0051642	centrosome localization	1.454850e-5
GO:0030186	melatonin metabolic process	1.475681e-5
GO:0070779	D-aspartate import	1.494848e-5
GO:0001525	angiogenesis	1.554875e-5
GO:0032722	positive regulation of chemokine production	1.590658e-5
GO:0052548	regulation of endopeptidase activity	1.640301e-5
GO:0032102	negative regulation of response to external stimulus	1.646167e-5
GO:0002757	immune response-activating signal transduction	1.676257e-5
GO:0045909	positive regulation of vasodilation	1.687545e-5
GO:0032273	positive regulation of protein polymerization	1.706472e-5
GO:0050871	positive regulation of B cell activation	1.711119e-5
GO:0070482	response to oxygen levels	1.716474e-5
GO:0048245	eosinophil chemotaxis	1.730383e-5
GO:0006542	glutamine biosynthetic process	1.733886e-5
GO:0070098	chemokine-mediated signaling pathway	1.739190e-5
GO:0001816	cytokine production	1.749576e-5
GO:0051969	regulation of transmission of nerve impulse	1.841388e-5
GO:0040037	negative regulation of fibroblast growth factor receptor signaling pathway	1.850429e-5
GO:0060442	branching involved in prostate gland morphogenesis	1.893955e-5
GO:0045184	establishment of protein localization	1.909957e-5
GO:0030036	actin cytoskeleton organization	1.919698e-5
GO:0033026	negative regulation of mast cell apoptosis	1.923726e-5
GO:0045598	regulation of fat cell differentiation	1.942401e-5
GO:0030730	sequestering of triglyceride	2.055972e-5
GO:0035583	negative regulation of transforming growth factor beta receptor signaling pathway by extracellular sequestering of TGFbeta	2.072830e-5
GO:0046622	positive regulation of organ growth	2.073537e-5
GO:0050670	regulation of lymphocyte proliferation	2.084935e-5
GO:2000370	positive regulation of clathrin-mediated endocytosis	2.133842e-5
GO:0022605	oogenesis stage	2.140216e-5
GO:0032409	regulation of transporter activity	2.149420e-5
GO:0015810	aspartate transport	2.163101e-5
GO:0002764	immune response-regulating signaling pathway	2.207573e-5
GO:0000096	sulfur amino acid metabolic process	2.219786e-5
GO:0030850	prostate gland development	2.258812e-5
GO:0045933	positive regulation of muscle contraction	2.261845e-5
GO:0051252	regulation of RNA metabolic process	2.332053e-5
GO:0051970	negative regulation of transmission of nerve impulse	2.540356e-5
GO:0010628	positive regulation of gene expression	2.548832e-5

GREAT analysis results for mouseGenomic Enrichment of Annotations Tool (GREAT, Nat Biotechnol. 2010 May;28(5):495-501) is used to identify, both in human and in mouse, the gene ontology terms of biological processes enriched given the predicted TFBSs, and evaluated the overlap in the top-500 gene ontology terms between human and mouse. For each novel motif, the P value for the overlap was then evaluated by calculating its relative rank with respect to this background distribution.<br>Analyst: Michiel de Hoon <br><br>link to source dataset <br>data

---

GO ID	GO Term	p-value
GO:0021854	hypothalamus development	9.240589e-10
GO:0022408	negative regulation of cell-cell adhesion	1.138578e-8
GO:0040017	positive regulation of locomotion	8.351531e-8
GO:0043056	forward locomotion	1.117029e-7
GO:0033058	directional locomotion	1.912454e-7
GO:0061081	positive regulation of myeloid leukocyte cytokine production involved in immune response	2.428167e-7
GO:0046640	regulation of alpha-beta T cell proliferation	3.225887e-7
GO:0006278	RNA-dependent DNA replication	3.467510e-7
GO:0006613	cotranslational protein targeting to membrane	3.779829e-7
GO:0060009	Sertoli cell development	4.385844e-7
GO:0060907	positive regulation of macrophage cytokine production	5.071554e-7
GO:0060008	Sertoli cell differentiation	8.403804e-7
GO:0010935	regulation of macrophage cytokine production	8.461705e-7
GO:0007162	negative regulation of cell adhesion	1.099598e-6
GO:0006614	SRP-dependent cotranslational protein targeting to membrane	1.307666e-6
GO:0009743	response to carbohydrate stimulus	2.085968e-6
GO:0046642	negative regulation of alpha-beta T cell proliferation	2.106090e-6
GO:0051272	positive regulation of cellular component movement	2.254064e-6
GO:2000147	positive regulation of cell motility	2.528090e-6
GO:0071223	cellular response to lipoteichoic acid	2.534258e-6
GO:0000187	activation of MAPK activity	2.573743e-6
GO:0043406	positive regulation of MAP kinase activity	2.719179e-6
GO:0032735	positive regulation of interleukin-12 production	3.593206e-6
GO:0032653	regulation of interleukin-10 production	4.143396e-6
GO:0006811	ion transport	4.351153e-6
GO:0071956	cellular component maintenance at cellular level	4.881105e-6
GO:0006756	AMP phosphorylation	5.587701e-6
GO:0046709	IDP catabolic process	6.775703e-6
GO:0046032	ADP catabolic process	6.775703e-6
GO:0045338	farnesyl diphosphate metabolic process	6.927811e-6
GO:0040012	regulation of locomotion	9.103205e-6
GO:0021700	developmental maturation	9.652829e-6
GO:0021604	cranial nerve structural organization	1.092406e-5
GO:0002861	regulation of inflammatory response to antigenic stimulus	1.103425e-5
GO:0048240	sperm capacitation	1.111900e-5
GO:0070663	regulation of leukocyte proliferation	1.116119e-5
GO:0032944	regulation of mononuclear cell proliferation	1.248452e-5
GO:0050670	regulation of lymphocyte proliferation	1.323242e-5
GO:0006629	lipid metabolic process	1.424132e-5
GO:0002891	positive regulation of immunoglobulin mediated immune response	1.427968e-5
GO:0002922	positive regulation of humoral immune response	1.491287e-5
GO:0051297	centrosome organization	1.589970e-5
GO:0045060	negative thymic T cell selection	1.589970e-5
GO:0045061	thymic T cell selection	1.757217e-5
GO:0009617	response to bacterium	1.830124e-5
GO:0030335	positive regulation of cell migration	1.845103e-5
GO:0051346	negative regulation of hydrolase activity	1.858695e-5
GO:0010466	negative regulation of peptidase activity	2.041112e-5
GO:0022610	biological adhesion	2.370412e-5
GO:0015672	monovalent inorganic cation transport	2.541226e-5
GO:0042753	positive regulation of circadian rhythm	2.715480e-5
GO:0042130	negative regulation of T cell proliferation	2.728993e-5
GO:0050777	negative regulation of immune response	2.859397e-5
GO:0002720	positive regulation of cytokine production involved in immune response	2.882155e-5
GO:0002683	negative regulation of immune system process	3.005406e-5
GO:0042790	transcription of nuclear large rRNA transcript from RNA polymerase I promoter	3.214722e-5
GO:0034126	positive regulation of MyD88-dependent toll-like receptor signaling pathway	3.258648e-5
GO:0021553	olfactory nerve development	3.403116e-5
GO:0019919	peptidyl-arginine methylation, to asymmetrical-dimethyl arginine	3.478227e-5
GO:0001810	regulation of type I hypersensitivity	3.478227e-5
GO:0060324	face development	3.488663e-5
GO:0090074	negative regulation of protein homodimerization activity	3.567433e-5
GO:0021629	olfactory nerve structural organization	3.567433e-5
GO:0022407	regulation of cell-cell adhesion	3.581308e-5
GO:0060307	regulation of ventricular cardiomyocyte membrane repolarization	3.930081e-5
GO:0060299	negative regulation of sarcomere organization	3.930081e-5
GO:0006812	cation transport	4.099421e-5
GO:0046940	nucleoside monophosphate phosphorylation	4.125255e-5
GO:0043954	cellular component maintenance	4.223089e-5
GO:0050672	negative regulation of lymphocyte proliferation	4.281221e-5
GO:0007155	cell adhesion	4.900134e-5
GO:0070314	G1 to G0 transition	5.077137e-5
GO:0060271	cilium morphogenesis	5.210564e-5
GO:0032760	positive regulation of tumor necrosis factor production	5.421595e-5
GO:0002761	regulation of myeloid leukocyte differentiation	5.528265e-5
GO:0043383	negative T cell selection	5.656086e-5
GO:0051915	induction of synaptic plasticity by chemical substance	5.862093e-5
GO:0002883	regulation of hypersensitivity	6.051916e-5
GO:0043486	histone exchange	6.094469e-5
GO:0071805	potassium ion transmembrane transport	6.451833e-5
GO:0007263	nitric oxide mediated signal transduction	6.518670e-5
GO:0046185	aldehyde catabolic process	6.607828e-5
GO:0051270	regulation of cellular component movement	7.092248e-5
GO:0051707	response to other organism	7.148354e-5
GO:0070664	negative regulation of leukocyte proliferation	7.152886e-5
GO:0002606	positive regulation of dendritic cell antigen processing and presentation	7.269860e-5
GO:0021602	cranial nerve morphogenesis	7.412389e-5
GO:0032273	positive regulation of protein polymerization	7.835684e-5
GO:0021631	optic nerve morphogenesis	7.999663e-5
GO:0031023	microtubule organizing center organization	8.409499e-5
GO:0072108	positive regulation of mesenchymal to epithelial transition involved in metanephros morphogenesis	8.604691e-5
GO:0070206	protein trimerization	8.615295e-5
GO:0032655	regulation of interleukin-12 production	8.624420e-5
GO:0060322	head development	9.011451e-5
GO:0051704	multi-organism process	9.031909e-5
GO:0042590	antigen processing and presentation of exogenous peptide antigen via MHC class I	9.908372e-5
GO:0042129	regulation of T cell proliferation	1.033790e-4
GO:0071404	cellular response to low-density lipoprotein particle stimulus	1.057481e-4
GO:0045059	positive thymic T cell selection	1.076861e-4
GO:0032755	positive regulation of interleukin-6 production	1.089315e-4
GO:0006547	histidine metabolic process	1.215183e-4
GO:0071731	response to nitric oxide	1.277894e-4
GO:0009636	response to toxin	1.309688e-4
GO:0051101	regulation of DNA binding	1.319897e-4
GO:0044262	cellular carbohydrate metabolic process	1.353998e-4
GO:0043519	regulation of myosin II filament organization	1.357847e-4
GO:0048630	skeletal muscle tissue growth	1.386507e-4
GO:0051817	modification of morphology or physiology of other organism involved in symbiotic interaction	1.400464e-4
GO:0001819	positive regulation of cytokine production	1.434614e-4
GO:0002604	regulation of dendritic cell antigen processing and presentation	1.478636e-4
GO:0015724	formate transport	1.492833e-4
GO:0006548	histidine catabolic process	1.496068e-4
GO:2000145	regulation of cell motility	1.500808e-4
GO:0060364	frontal suture morphogenesis	1.541743e-4
GO:0032656	regulation of interleukin-13 production	1.544949e-4
GO:0033993	response to lipid	1.774324e-4
GO:0048793	pronephros development	1.803640e-4
GO:0070434	positive regulation of nucleotide-binding oligomerization domain containing 2 signaling pathway	1.823508e-4
GO:0070430	positive regulation of nucleotide-binding oligomerization domain containing 1 signaling pathway	1.823508e-4
GO:0045362	positive regulation of interleukin-1 biosynthetic process	1.823508e-4
GO:0032707	negative regulation of interleukin-23 production	1.823508e-4
GO:0071402	cellular response to lipoprotein particle stimulus	1.870481e-4
GO:0006952	defense response	1.952139e-4
GO:0008610	lipid biosynthetic process	1.952839e-4
GO:0007185	transmembrane receptor protein tyrosine phosphatase signaling pathway	1.955578e-4
GO:0009408	response to heat	1.993508e-4
GO:0045217	cell-cell junction maintenance	1.997849e-4
GO:0055096	low-density lipoprotein particle mediated signaling	2.024230e-4
GO:0020028	hemoglobin import	2.048929e-4
GO:0046634	regulation of alpha-beta T cell activation	2.078184e-4
GO:0050868	negative regulation of T cell activation	2.126818e-4
GO:0034097	response to cytokine stimulus	2.146077e-4
GO:0008299	isoprenoid biosynthetic process	2.155463e-4
GO:0060042	retina morphogenesis in camera-type eye	2.194798e-4
GO:0009181	purine ribonucleoside diphosphate catabolic process	2.260861e-4
GO:0097035	regulation of membrane lipid distribution	2.467418e-4
GO:0009607	response to biotic stimulus	2.475867e-4
GO:0050770	regulation of axonogenesis	2.497927e-4
GO:0072384	organelle transport along microtubule	2.529464e-4
GO:0032570	response to progesterone stimulus	2.640984e-4
GO:0055114	oxidation-reduction process	2.659005e-4
GO:0033189	response to vitamin A	2.695478e-4
GO:0006950	response to stress	2.707119e-4
GO:0055085	transmembrane transport	2.821726e-4
GO:0007243	intracellular protein kinase cascade	2.853515e-4
GO:0045843	negative regulation of striated muscle tissue development	2.861309e-4
GO:0047497	mitochondrion transport along microtubule	2.908121e-4
GO:0007184	SMAD protein import into nucleus	2.908121e-4
GO:0007257	activation of JUN kinase activity	3.044788e-4
GO:0031638	zymogen activation	3.045288e-4
GO:0016090	prenol metabolic process	3.275032e-4
GO:0006820	anion transport	3.315608e-4
GO:0032534	regulation of microvillus assembly	3.353124e-4
GO:0005975	carbohydrate metabolic process	3.374031e-4
GO:0051531	NFAT protein import into nucleus	3.397746e-4
GO:0034605	cellular response to heat	3.512101e-4
GO:0010951	negative regulation of endopeptidase activity	3.564823e-4
GO:0042775	mitochondrial ATP synthesis coupled electron transport	3.611250e-4
GO:0051795	positive regulation of catagen	3.611889e-4
GO:0042628	mating plug formation	3.611889e-4
GO:0051654	establishment of mitochondrion localization	3.746033e-4
GO:0015695	organic cation transport	3.871542e-4
GO:0006882	cellular zinc ion homeostasis	3.992728e-4
GO:0050730	regulation of peptidyl-tyrosine phosphorylation	4.106120e-4
GO:0010638	positive regulation of organelle organization	4.209242e-4
GO:0015701	bicarbonate transport	4.298520e-4
GO:0060100	positive regulation of phagocytosis, engulfment	4.345674e-4
GO:0061153	trachea gland development	4.498991e-4
GO:0007217	tachykinin receptor signaling pathway	4.498991e-4
GO:0032733	positive regulation of interleukin-10 production	4.500269e-4
GO:0071902	positive regulation of protein serine/threonine kinase activity	4.521781e-4
GO:0007584	response to nutrient	4.613689e-4
GO:0002864	regulation of acute inflammatory response to antigenic stimulus	4.670165e-4
GO:0006054	N-acetylneuraminate metabolic process	4.820674e-4
GO:0002923	regulation of humoral immune response mediated by circulating immunoglobulin	4.883122e-4
GO:0050896	response to stimulus	4.889190e-4
GO:0043967	histone H4 acetylation	5.045606e-4
GO:0048818	positive regulation of hair follicle maturation	5.063632e-4
GO:0009611	response to wounding	5.156292e-4
GO:0046636	negative regulation of alpha-beta T cell activation	5.326978e-4
GO:0021965	spinal cord ventral commissure morphogenesis	5.401978e-4
GO:0050771	negative regulation of axonogenesis	5.423777e-4
GO:0032673	regulation of interleukin-4 production	5.439431e-4
GO:0002925	positive regulation of humoral immune response mediated by circulating immunoglobulin	5.442156e-4
GO:0071732	cellular response to nitric oxide	5.650427e-4
GO:0033630	positive regulation of cell adhesion mediated by integrin	5.650427e-4
GO:0008272	sulfate transport	5.650427e-4
GO:0034509	centromeric core chromatin assembly	5.665454e-4
GO:0034080	CenH3-containing nucleosome assembly at centromere	5.665454e-4
GO:0033634	positive regulation of cell-cell adhesion mediated by integrin	5.691142e-4
GO:0006463	steroid hormone receptor complex assembly	5.691142e-4
GO:0097115	neurexin clustering	5.795400e-4
GO:0046031	ADP metabolic process	5.795400e-4
GO:0019934	cGMP-mediated signaling	5.836128e-4
GO:0043615	astrocyte cell migration	5.947456e-4
GO:0051250	negative regulation of lymphocyte activation	6.038294e-4
GO:0031953	negative regulation of protein autophosphorylation	6.091227e-4
GO:0030334	regulation of cell migration	6.131867e-4
GO:0002718	regulation of cytokine production involved in immune response	6.154425e-4
GO:0045605	negative regulation of epidermal cell differentiation	6.230434e-4
GO:0060056	mammary gland involution	6.339330e-4
GO:0048469	cell maturation	6.437699e-4
GO:0032789	unsaturated monocarboxylic acid metabolic process	6.547660e-4
GO:0042840	D-glucuronate catabolic process	6.547660e-4
GO:0032788	saturated monocarboxylic acid metabolic process	6.547660e-4
GO:0000379	tRNA-type intron splice site recognition and cleavage	6.547660e-4
GO:0006760	folic acid-containing compound metabolic process	6.559225e-4
GO:0044403	symbiosis, encompassing mutualism through parasitism	6.691349e-4
GO:0009167	purine ribonucleoside monophosphate metabolic process	6.870172e-4
GO:0031344	regulation of cell projection organization	6.966720e-4
GO:0071221	cellular response to bacterial lipopeptide	6.988167e-4
GO:0061205	paramesonephric duct development	6.989786e-4
GO:0007098	centrosome cycle	7.137237e-4
GO:0045047	protein targeting to ER	7.162324e-4
GO:0048635	negative regulation of muscle organ development	7.170517e-4
GO:0031334	positive regulation of protein complex assembly	7.200408e-4
GO:2000334	positive regulation of blood microparticle formation	7.251278e-4
GO:2000412	positive regulation of thymocyte migration	7.251278e-4
GO:0021536	diencephalon development	7.307254e-4
GO:0002885	positive regulation of hypersensitivity	7.456551e-4
GO:0042953	lipoprotein transport	7.661912e-4
GO:0045938	positive regulation of circadian sleep/wake cycle, sleep	8.030495e-4
GO:0032103	positive regulation of response to external stimulus	8.107479e-4
GO:0007519	skeletal muscle tissue development	8.136834e-4
GO:0010975	regulation of neuron projection development	8.168505e-4
GO:0050866	negative regulation of cell activation	8.210905e-4
GO:0002862	negative regulation of inflammatory response to antigenic stimulus	8.267239e-4
GO:0031116	positive regulation of microtubule polymerization	8.295118e-4
GO:0032355	response to estradiol stimulus	8.381153e-4
GO:2000594	positive regulation of metanephric DCT cell differentiation	8.406942e-4
GO:0039003	pronephric field specification	8.406942e-4
GO:0072305	negative regulation of mesenchymal stem cell apoptosis involved in metanephric nephron morphogenesis	8.406942e-4
GO:0043405	regulation of MAP kinase activity	8.439300e-4
GO:0031099	regeneration	8.657950e-4
GO:0046033	AMP metabolic process	8.797479e-4
GO:0010942	positive regulation of cell death	8.861236e-4
GO:0006909	phagocytosis	9.145452e-4
GO:0051646	mitochondrion localization	9.187269e-4
GO:0055098	response to low-density lipoprotein particle stimulus	9.264359e-4
GO:0046005	positive regulation of circadian sleep/wake cycle, REM sleep	9.564213e-4
GO:0031952	regulation of protein autophosphorylation	9.799514e-4
GO:0050764	regulation of phagocytosis	9.801582e-4
GO:0055069	zinc ion homeostasis	9.836760e-4
GO:0010793	regulation of mRNA export from nucleus	1.020377e-3
GO:0015711	organic anion transport	1.048625e-3
GO:0050792	regulation of viral reproduction	1.051142e-3
GO:0048679	regulation of axon regeneration	1.055870e-3
GO:0035880	embryonic nail plate morphogenesis	1.058679e-3
GO:0042320	regulation of circadian sleep/wake cycle, REM sleep	1.071472e-3
GO:0050731	positive regulation of peptidyl-tyrosine phosphorylation	1.074870e-3
GO:0002700	regulation of production of molecular mediator of immune response	1.099841e-3
GO:0044419	interspecies interaction between organisms	1.103184e-3
GO:0015697	quaternary ammonium group transport	1.107039e-3
GO:0061360	optic chiasma development	1.123965e-3
GO:0035799	ureter maturation	1.123965e-3
GO:2000597	positive regulation of optic nerve formation	1.123965e-3
GO:0021650	vestibulocochlear nerve formation	1.123965e-3
GO:0021633	optic nerve structural organization	1.123965e-3
GO:0048532	anatomical structure arrangement	1.133244e-3
GO:0046069	cGMP catabolic process	1.148764e-3
GO:0070670	response to interleukin-4	1.150058e-3
GO:0002863	positive regulation of inflammatory response to antigenic stimulus	1.159679e-3
GO:0010592	positive regulation of lamellipodium assembly	1.166518e-3
GO:0051280	negative regulation of release of sequestered calcium ion into cytosol	1.173749e-3
GO:0048069	eye pigmentation	1.175583e-3
GO:0009396	folic acid-containing compound biosynthetic process	1.175583e-3
GO:0030307	positive regulation of cell growth	1.178566e-3
GO:0018298	protein-chromophore linkage	1.181327e-3
GO:0050766	positive regulation of phagocytosis	1.188872e-3
GO:0001558	regulation of cell growth	1.230903e-3
GO:0072003	kidney rudiment formation	1.268490e-3
GO:0021562	vestibulocochlear nerve development	1.268490e-3
GO:0051597	response to methylmercury	1.316368e-3
GO:0048545	response to steroid hormone stimulus	1.318155e-3
GO:0008202	steroid metabolic process	1.320503e-3
GO:0032689	negative regulation of interferon-gamma production	1.402027e-3
GO:0032722	positive regulation of chemokine production	1.427409e-3
GO:0034113	heterotypic cell-cell adhesion	1.430973e-3
GO:0042773	ATP synthesis coupled electron transport	1.437634e-3
GO:0002407	dendritic cell chemotaxis	1.446447e-3
GO:0046459	short-chain fatty acid metabolic process	1.446447e-3
GO:0021761	limbic system development	1.452277e-3
GO:0009108	coenzyme biosynthetic process	1.455449e-3
GO:0005996	monosaccharide metabolic process	1.472311e-3
GO:0060363	cranial suture morphogenesis	1.472583e-3
GO:0046641	positive regulation of alpha-beta T cell proliferation	1.476916e-3
GO:0042060	wound healing	1.480179e-3
GO:0006561	proline biosynthetic process	1.481975e-3
GO:0060040	retinal bipolar neuron differentiation	1.545576e-3
GO:0042276	error-prone translesion synthesis	1.545576e-3
GO:2000696	regulation of epithelial cell differentiation involved in kidney development	1.555646e-3
GO:0072307	regulation of metanephric nephron tubule epithelial cell differentiation	1.584448e-3
GO:0009612	response to mechanical stimulus	1.594591e-3
GO:0009179	purine ribonucleoside diphosphate metabolic process	1.608897e-3
GO:0050830	defense response to Gram-positive bacterium	1.615072e-3
GO:0048520	positive regulation of behavior	1.619125e-3
GO:0043065	positive regulation of apoptosis	1.663997e-3
GO:0061379	inferior colliculus development	1.665731e-3
GO:0061381	cell migration in diencephalon	1.665731e-3
GO:0061374	mammillothalamic axonal tract development	1.665731e-3
GO:0046292	formaldehyde metabolic process	1.665731e-3
GO:0021855	hypothalamus cell migration	1.665731e-3
GO:0032387	negative regulation of intracellular transport	1.688523e-3
GO:0010720	positive regulation of cell development	1.696387e-3
GO:0043372	positive regulation of CD4-positive, alpha-beta T cell differentiation	1.708361e-3
GO:0030852	regulation of granulocyte differentiation	1.713191e-3
GO:0030854	positive regulation of granulocyte differentiation	1.715203e-3
GO:0006732	coenzyme metabolic process	1.738061e-3
GO:0002920	regulation of humoral immune response	1.738665e-3
GO:0071447	cellular response to hydroperoxide	1.778682e-3
GO:0015911	plasma membrane long-chain fatty acid transport	1.778682e-3
GO:0018149	peptide cross-linking	1.786738e-3
GO:0060323	head morphogenesis	1.794735e-3
GO:0021943	formation of radial glial scaffolds	1.800332e-3
GO:0010738	regulation of protein kinase A signaling cascade	1.814212e-3
GO:0034284	response to monosaccharide stimulus	1.818642e-3
GO:0034969	histone arginine methylation	1.818693e-3
GO:0006360	transcription from RNA polymerase I promoter	1.830846e-3
GO:0010763	positive regulation of fibroblast migration	1.830846e-3
GO:0032649	regulation of interferon-gamma production	1.845607e-3
GO:0003339	regulation of mesenchymal to epithelial transition involved in metanephros morphogenesis	1.847400e-3
GO:0051299	centrosome separation	1.861409e-3
GO:0048676	axon extension involved in development	1.940797e-3
GO:0002682	regulation of immune system process	1.976644e-3
GO:0060554	induction of necroptosis of activated-T cells	1.982052e-3
GO:0006104	succinyl-CoA metabolic process	1.982052e-3
GO:0043068	positive regulation of programmed cell death	1.984023e-3
GO:0060538	skeletal muscle organ development	1.993987e-3
GO:0060325	face morphogenesis	2.010085e-3
GO:0009311	oligosaccharide metabolic process	2.071716e-3
GO:0031112	positive regulation of microtubule polymerization or depolymerization	2.097381e-3
GO:0009566	fertilization	2.160652e-3
GO:0001805	positive regulation of type III hypersensitivity	2.180903e-3
GO:0050854	regulation of antigen receptor-mediated signaling pathway	2.210664e-3
GO:0090072	positive regulation of sodium ion transport via voltage-gated sodium channel activity	2.221943e-3
GO:0046666	retinal cell programmed cell death	2.221943e-3
GO:0001812	positive regulation of type I hypersensitivity	2.221943e-3
GO:0050806	positive regulation of synaptic transmission	2.233272e-3
GO:0045368	positive regulation of interleukin-13 biosynthetic process	2.280744e-3
GO:0001959	regulation of cytokine-mediated signaling pathway	2.298643e-3
GO:0002063	chondrocyte development	2.302067e-3
GO:0048515	spermatid differentiation	2.322702e-3
GO:0071895	odontoblast differentiation	2.331186e-3
GO:0030195	negative regulation of blood coagulation	2.335997e-3
GO:0007165	signal transduction	2.397618e-3
GO:0050900	leukocyte migration	2.476139e-3
GO:0051495	positive regulation of cytoskeleton organization	2.506636e-3
GO:0034383	low-density lipoprotein particle clearance	2.523089e-3
GO:0007530	sex determination	2.575594e-3
GO:0043507	positive regulation of JUN kinase activity	2.585788e-3
GO:0032680	regulation of tumor necrosis factor production	2.585788e-3
GO:0002866	positive regulation of acute inflammatory response to antigenic stimulus	2.594591e-3
GO:0097022	lymphocyte migration into lymph node	2.618839e-3
GO:0072610	interleukin-12 secretion	2.618839e-3
GO:0070571	negative regulation of neuron projection regeneration	2.631415e-3
GO:0051130	positive regulation of cellular component organization	2.643726e-3
GO:0050857	positive regulation of antigen receptor-mediated signaling pathway	2.696989e-3
GO:0002889	regulation of immunoglobulin mediated immune response	2.703943e-3
GO:0007041	lysosomal transport	2.715702e-3
GO:0008347	glial cell migration	2.751419e-3
GO:0021861	forebrain radial glial cell differentiation	2.751970e-3
GO:0010171	body morphogenesis	2.760728e-3
GO:0045063	T-helper 1 cell differentiation	2.762294e-3
GO:0010996	response to auditory stimulus	2.776185e-3
GO:0030328	prenylcysteine catabolic process	2.776185e-3
GO:0015969	guanosine tetraphosphate metabolic process	2.776185e-3
GO:0002638	negative regulation of immunoglobulin production	2.776185e-3
GO:0001811	negative regulation of type I hypersensitivity	2.776185e-3
GO:0042742	defense response to bacterium	2.817663e-3
GO:0009746	response to hexose stimulus	2.820092e-3
GO:0043506	regulation of JUN kinase activity	2.857661e-3
GO:0007320	insemination	2.878723e-3
GO:0044003	modification by symbiont of host morphology or physiology	2.881171e-3
GO:0045348	positive regulation of MHC class II biosynthetic process	2.882515e-3
GO:0048592	eye morphogenesis	2.892307e-3
GO:0046939	nucleotide phosphorylation	2.916830e-3
GO:0046381	CMP-N-acetylneuraminate metabolic process	2.917285e-3
GO:0030595	leukocyte chemotaxis	2.922663e-3
GO:0048732	gland development	2.925894e-3
GO:0046037	GMP metabolic process	2.929226e-3
GO:0034088	maintenance of mitotic sister chromatid cohesion	2.929226e-3
GO:0000086	G2/M transition of mitotic cell cycle	2.977353e-3
GO:0031111	negative regulation of microtubule polymerization or depolymerization	2.981949e-3
GO:0032329	serine transport	3.015800e-3
GO:0051919	positive regulation of fibrinolysis	3.015800e-3
GO:0033563	dorsal/ventral axon guidance	3.015800e-3
GO:0051615	histamine uptake	3.028922e-3
GO:0033603	positive regulation of dopamine secretion	3.028922e-3
GO:0034498	early endosome to Golgi transport	3.028922e-3
GO:0060900	embryonic camera-type eye formation	3.060332e-3
GO:0071780	mitotic cell cycle G2/M transition checkpoint	3.100807e-3
GO:0032781	positive regulation of ATPase activity	3.119132e-3
GO:0042558	pteridine-containing compound metabolic process	3.208983e-3
GO:0030001	metal ion transport	3.210152e-3
GO:0070371	ERK1 and ERK2 cascade	3.273658e-3
GO:0070076	histone lysine demethylation	3.273658e-3
GO:0030516	regulation of axon extension	3.285355e-3
GO:0045058	T cell selection	3.294595e-3
GO:0002820	negative regulation of adaptive immune response	3.403151e-3
GO:0006813	potassium ion transport	3.414038e-3
GO:2000756	regulation of peptidyl-lysine acetylation	3.430795e-3
GO:0021983	pituitary gland development	3.434257e-3
GO:0060759	regulation of response to cytokine stimulus	3.456453e-3
GO:0048193	Golgi vesicle transport	3.469065e-3
GO:0031345	negative regulation of cell projection organization	3.494988e-3
GO:0014012	peripheral nervous system axon regeneration	3.516944e-3
GO:0032023	trypsinogen activation	3.533920e-3
GO:0061037	negative regulation of cartilage development	3.586373e-3
GO:0050765	negative regulation of phagocytosis	3.586373e-3
GO:0045627	positive regulation of T-helper 1 cell differentiation	3.621755e-3
GO:0002830	positive regulation of type 2 immune response	3.621755e-3
GO:0035106	operant conditioning	3.633477e-3
GO:0045860	positive regulation of protein kinase activity	3.634307e-3
GO:0048845	venous blood vessel morphogenesis	3.648412e-3
GO:0045596	negative regulation of cell differentiation	3.651806e-3
GO:0031645	negative regulation of neurological system process	3.710845e-3
GO:0032530	regulation of microvillus organization	3.724835e-3
GO:0031529	ruffle organization	3.739761e-3
GO:0051971	positive regulation of transmission of nerve impulse	3.742690e-3
GO:0048639	positive regulation of developmental growth	3.743792e-3
GO:0032496	response to lipopolysaccharide	3.773806e-3
GO:0031113	regulation of microtubule polymerization	3.776863e-3
GO:0006006	glucose metabolic process	3.790777e-3
GO:0014059	regulation of dopamine secretion	3.812517e-3
GO:0010812	negative regulation of cell-substrate adhesion	3.888882e-3
GO:0033273	response to vitamin	3.892586e-3
GO:0097026	dendritic cell dendrite assembly	3.897621e-3
GO:0006122	mitochondrial electron transport, ubiquinol to cytochrome c	3.897621e-3
GO:0002237	response to molecule of bacterial origin	3.903431e-3
GO:0051494	negative regulation of cytoskeleton organization	3.904519e-3
GO:0010639	negative regulation of organelle organization	3.946589e-3
GO:0060019	radial glial cell differentiation	3.970909e-3
GO:0048524	positive regulation of viral reproduction	3.983897e-3
GO:0002762	negative regulation of myeloid leukocyte differentiation	3.983897e-3
GO:0032713	negative regulation of interleukin-4 production	4.005154e-3
GO:0070507	regulation of microtubule cytoskeleton organization	4.041647e-3
GO:0001960	negative regulation of cytokine-mediated signaling pathway	4.049078e-3
GO:0002669	positive regulation of T cell anergy	4.064748e-3
GO:2000171	negative regulation of dendrite development	4.093361e-3
GO:0050855	regulation of B cell receptor signaling pathway	4.170495e-3
GO:0010769	regulation of cell morphogenesis involved in differentiation	4.179865e-3
GO:0060992	response to fungicide	4.193822e-3
GO:0010544	negative regulation of platelet activation	4.211374e-3
GO:0052547	regulation of peptidase activity	4.243345e-3
GO:0018195	peptidyl-arginine modification	4.275571e-3
GO:0035710	CD4-positive, alpha-beta T cell activation	4.339130e-3
GO:0022409	positive regulation of cell-cell adhesion	4.347740e-3
GO:0032615	interleukin-12 production	4.353571e-3
GO:0043310	negative regulation of eosinophil degranulation	4.372480e-3
GO:2000409	positive regulation of T cell extravasation	4.372480e-3
GO:0035705	T-helper 17 cell chemotaxis	4.372480e-3
GO:0033210	leptin-mediated signaling pathway	4.372480e-3
GO:0035696	monocyte extravasation	4.372480e-3
GO:0014878	response to electrical stimulus involved in regulation of muscle adaptation	4.372480e-3
GO:0006637	acyl-CoA metabolic process	4.382318e-3
GO:0048170	positive regulation of long-term neuronal synaptic plasticity	4.462117e-3
GO:0002678	positive regulation of chronic inflammatory response	4.462117e-3
GO:0030223	neutrophil differentiation	4.462117e-3
GO:0022600	digestive system process	4.496141e-3
GO:0072300	positive regulation of metanephric glomerulus development	4.521225e-3
GO:0033605	positive regulation of catecholamine secretion	4.521225e-3
GO:2000378	negative regulation of reactive oxygen species metabolic process	4.549913e-3
GO:2000121	regulation of removal of superoxide radicals	4.555213e-3
GO:0015825	L-serine transport	4.586737e-3
GO:0010519	negative regulation of phospholipase activity	4.640939e-3
GO:0060452	positive regulation of cardiac muscle contraction	4.640939e-3
GO:0032729	positive regulation of interferon-gamma production	4.650234e-3
GO:0043044	ATP-dependent chromatin remodeling	4.679668e-3
GO:0060841	venous blood vessel development	4.731147e-3
GO:0031646	positive regulation of neurological system process	4.767000e-3
GO:0051970	negative regulation of transmission of nerve impulse	4.803267e-3
GO:0090023	positive regulation of neutrophil chemotaxis	4.813166e-3
GO:0015893	drug transport	4.869922e-3
GO:2000401	regulation of lymphocyte migration	4.881804e-3
GO:0070972	protein localization in endoplasmic reticulum	4.890636e-3
GO:0070849	response to epidermal growth factor stimulus	4.890636e-3
GO:0042147	retrograde transport, endosome to Golgi	4.891250e-3
GO:0032642	regulation of chemokine production	4.893218e-3
GO:0044255	cellular lipid metabolic process	4.978024e-3
GO:0046635	positive regulation of alpha-beta T cell activation	4.980716e-3
GO:0002823	negative regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains	4.994429e-3
GO:0006482	protein demethylation	4.994429e-3
GO:0061387	regulation of extent of cell growth	5.033027e-3
GO:0045074	regulation of interleukin-10 biosynthetic process	5.035046e-3
GO:0010560	positive regulation of glycoprotein biosynthetic process	5.035046e-3
GO:0050865	regulation of cell activation	5.035169e-3
GO:0010040	response to iron(II) ion	5.089234e-3
GO:0001774	microglial cell activation	5.089234e-3
GO:0045081	negative regulation of interleukin-10 biosynthetic process	5.101209e-3
GO:0010389	regulation of G2/M transition of mitotic cell cycle	5.133098e-3
GO:0002702	positive regulation of production of molecular mediator of immune response	5.192422e-3
GO:0008333	endosome to lysosome transport	5.194427e-3
GO:0070542	response to fatty acid	5.205325e-3
GO:2000602	regulation of interphase of mitotic cell cycle	5.209651e-3
GO:0016577	histone demethylation	5.210328e-3
GO:0035246	peptidyl-arginine N-methylation	5.280983e-3
GO:0043923	positive regulation by host of viral transcription	5.290298e-3
GO:0002695	negative regulation of leukocyte activation	5.369701e-3
GO:0043551	regulation of phosphatidylinositol 3-kinase activity	5.426543e-3
GO:0045071	negative regulation of viral genome replication	5.437517e-3