Novel motif:92

name:	motif92_GCGKWWNAA

Association to promoter expression in human samples<b>Summary:</b>Significance of the correlation with CAGE expression, human <br><b>Analyst:</b> Michiel de Hoon<br><br>link to source dataset <br>data

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Association to promoter expression in mouse samples <b>Summary:</b>Significance of the correlation with CAGE expression, mouse <br><b>Analyst:</b> Michiel de Hoon<br><br>link to source dataset <br>data

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GREAT analysis results for human <b>Summary:</b>Genomic Enrichment of Annotations Tool (GREAT, Nat Biotechnol. 2010 May;28(5):495-501) is used to identify, both in human and in mouse, the gene ontology terms of biological processes enriched given the predicted TFBSs, and evaluated the overlap in the top-500 gene ontology terms between human and mouse. For each novel motif, the P value for the overlap was then evaluated by calculating its relative rank with respect to this background distribution.<br>Analyst: Michiel de Hoon<br><br>link to source dataset <br>data

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GO ID	GO Term	p-value
GO:0019058	viral infectious cycle	2.188171e-16
GO:0071156	regulation of cell cycle arrest	1.129977e-14
GO:0000075	cell cycle checkpoint	3.326130e-13
GO:0022415	viral reproductive process	1.565818e-12
GO:0006414	translational elongation	1.755536e-12
GO:0019083	viral transcription	2.059186e-12
GO:0006415	translational termination	9.854023e-12
GO:0034623	cellular macromolecular complex disassembly	1.909819e-11
GO:0071845	cellular component disassembly at cellular level	2.828610e-11
GO:0022411	cellular component disassembly	7.994682e-11
GO:0032984	macromolecular complex disassembly	9.133804e-11
GO:0016032	viral reproduction	1.050183e-10
GO:0043624	cellular protein complex disassembly	1.750861e-10
GO:0030262	apoptotic nuclear change	5.568574e-10
GO:0043241	protein complex disassembly	9.325197e-10
GO:0000236	mitotic prometaphase	2.296125e-9
GO:0000088	mitotic prophase	4.259476e-9
GO:0006412	translation	8.154606e-9
GO:0043161	proteasomal ubiquitin-dependent protein catabolic process	1.211092e-8
GO:0016071	mRNA metabolic process	1.253234e-8
GO:0010498	proteasomal protein catabolic process	1.385914e-8
GO:0048280	vesicle fusion with Golgi apparatus	1.532698e-8
GO:0097039	protein linear polyubiquitination	2.017070e-8
GO:0007208	activation of phospholipase C activity by serotonin receptor signaling pathway	2.394444e-8
GO:0007094	mitotic cell cycle spindle assembly checkpoint	3.760990e-8
GO:0010564	regulation of cell cycle process	4.228090e-8
GO:0051436	negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle	5.074410e-8
GO:0007093	mitotic cell cycle checkpoint	5.085028e-8
GO:0022403	cell cycle phase	5.177915e-8
GO:0071173	spindle assembly checkpoint	5.205839e-8
GO:0071174	mitotic cell cycle spindle checkpoint	5.551587e-8
GO:0000278	mitotic cell cycle	6.550270e-8
GO:0021846	cell proliferation in forebrain	7.330348e-8
GO:0045841	negative regulation of mitotic metaphase/anaphase transition	8.650745e-8
GO:0031577	spindle checkpoint	9.208132e-8
GO:0045906	negative regulation of vasoconstriction	1.367649e-7
GO:0000279	M phase	1.529193e-7
GO:0022027	interkinetic nuclear migration	1.549884e-7
GO:0016480	negative regulation of transcription from RNA polymerase III promoter	1.702430e-7
GO:0048285	organelle fission	1.908396e-7
GO:2000659	regulation of interleukin-1-mediated signaling pathway	2.388695e-7
GO:0090304	nucleic acid metabolic process	2.483572e-7
GO:0000209	protein polyubiquitination	2.620196e-7
GO:0090281	negative regulation of calcium ion import	3.257041e-7
GO:0071584	negative regulation of zinc ion import	3.257041e-7
GO:0034660	ncRNA metabolic process	3.299663e-7
GO:0007067	mitosis	3.914136e-7
GO:0032581	ER-dependent peroxisome organization	4.240947e-7
GO:0006139	nucleobase-containing compound metabolic process	4.698343e-7
GO:0010506	regulation of autophagy	4.995173e-7
GO:0031167	rRNA methylation	5.318902e-7
GO:0045005	maintenance of fidelity involved in DNA-dependent DNA replication	6.955858e-7
GO:0035928	rRNA import into mitochondrion	6.959549e-7
GO:0042254	ribosome biogenesis	9.126449e-7
GO:0051351	positive regulation of ligase activity	1.039641e-6
GO:0000087	M phase of mitotic cell cycle	1.090721e-6
GO:0034766	negative regulation of ion transmembrane transport	1.133276e-6
GO:0051439	regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle	1.190870e-6
GO:0045839	negative regulation of mitosis	1.221896e-6
GO:0010587	miRNA catabolic process	1.403697e-6
GO:0031145	anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process	1.624583e-6
GO:0051647	nucleus localization	1.698575e-6
GO:0010310	regulation of hydrogen peroxide metabolic process	1.965080e-6
GO:0090305	nucleic acid phosphodiester bond hydrolysis	1.978067e-6
GO:0051029	rRNA transport	1.988893e-6
GO:0046796	viral genome transport in host cell	2.009909e-6
GO:0006611	protein export from nucleus	2.138495e-6
GO:0006396	RNA processing	2.538772e-6
GO:0000154	rRNA modification	2.544613e-6
GO:0031018	endocrine pancreas development	2.546581e-6
GO:0080009	mRNA methylation	2.613476e-6
GO:0042255	ribosome assembly	3.251503e-6
GO:0001510	RNA methylation	3.290727e-6
GO:0042396	phosphagen biosynthetic process	3.971843e-6
GO:0051340	regulation of ligase activity	4.582390e-6
GO:0071585	detoxification of cadmium ion	5.010060e-6
GO:0051443	positive regulation of ubiquitin-protein ligase activity	5.373093e-6
GO:0048387	negative regulation of retinoic acid receptor signaling pathway	5.525514e-6
GO:0071158	positive regulation of cell cycle arrest	6.030938e-6
GO:0010467	gene expression	6.270685e-6
GO:0006309	DNA fragmentation involved in apoptotic nuclear change	6.525095e-6
GO:0033574	response to testosterone stimulus	7.637376e-6
GO:0030071	regulation of mitotic metaphase/anaphase transition	7.706036e-6
GO:0070979	protein K11-linked ubiquitination	7.964025e-6
GO:0046479	glycosphingolipid catabolic process	8.640619e-6
GO:0031297	replication fork processing	1.030098e-5
GO:0051301	cell division	1.096540e-5
GO:0046314	phosphocreatine biosynthetic process	1.105328e-5
GO:0031398	positive regulation of protein ubiquitination	1.111935e-5
GO:0034728	nucleosome organization	1.152567e-5
GO:0006529	asparagine biosynthetic process	1.262170e-5
GO:0031570	DNA integrity checkpoint	1.336589e-5
GO:0035229	positive regulation of glutamate-cysteine ligase activity	1.456798e-5
GO:0000077	DNA damage checkpoint	1.763597e-5
GO:0006552	leucine catabolic process	1.791181e-5
GO:0044265	cellular macromolecule catabolic process	1.873461e-5
GO:0051974	negative regulation of telomerase activity	2.012923e-5
GO:0034641	cellular nitrogen compound metabolic process	2.121764e-5
GO:0051438	regulation of ubiquitin-protein ligase activity	2.122094e-5
GO:0000712	resolution of meiotic recombination intermediates	2.168060e-5
GO:0051444	negative regulation of ubiquitin-protein ligase activity	2.196926e-5
GO:0071539	protein localization to centrosome	2.259085e-5
GO:0007346	regulation of mitotic cell cycle	2.786225e-5
GO:0022402	cell cycle process	3.120399e-5
GO:0034453	microtubule anchoring	3.185071e-5
GO:0046477	glycosylceramide catabolic process	3.220593e-5
GO:0071843	cellular component biogenesis at cellular level	3.302640e-5
GO:0006458	'de novo' protein folding	3.598477e-5
GO:0046950	cellular ketone body metabolic process	3.970687e-5
GO:0022613	ribonucleoprotein complex biogenesis	3.973772e-5
GO:0051437	positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle	4.113440e-5
GO:0016073	snRNA metabolic process	4.308962e-5
GO:0051041	positive regulation of calcium-independent cell-cell adhesion	4.329904e-5
GO:0050902	leukocyte adhesive activation	4.329904e-5
GO:0002502	peptide antigen assembly with MHC class I protein complex	4.357003e-5
GO:0051603	proteolysis involved in cellular protein catabolic process	4.406292e-5
GO:0006268	DNA unwinding involved in replication	4.414427e-5
GO:0006398	histone mRNA 3'-end processing	4.640288e-5
GO:0034470	ncRNA processing	4.973677e-5
GO:0031575	mitotic cell cycle G1/S transition checkpoint	5.134387e-5
GO:0032446	protein modification by small protein conjugation	5.195371e-5
GO:0032365	intracellular lipid transport	6.300011e-5
GO:0006511	ubiquitin-dependent protein catabolic process	6.608485e-5
GO:0031427	response to methotrexate	6.785454e-5
GO:0016567	protein ubiquitination	6.972145e-5
GO:0008334	histone mRNA metabolic process	7.159845e-5
GO:0043550	regulation of lipid kinase activity	7.203897e-5
GO:0006333	chromatin assembly or disassembly	7.537957e-5
GO:0046951	ketone body biosynthetic process	7.743651e-5
GO:0030953	astral microtubule organization	7.917097e-5
GO:0031396	regulation of protein ubiquitination	7.925107e-5
GO:0034621	cellular macromolecular complex subunit organization	7.988224e-5
GO:0019941	modification-dependent protein catabolic process	8.021843e-5
GO:0006353	transcription termination, DNA-dependent	8.159446e-5
GO:0034661	ncRNA catabolic process	8.558906e-5
GO:0071779	G1/S transition checkpoint	9.003607e-5
GO:0006977	DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest	9.118580e-5
GO:0034080	CenH3-containing nucleosome assembly at centromere	9.399666e-5
GO:0071894	histone H2B conserved C-terminal lysine ubiquitination	9.403836e-5
GO:0021933	radial glia guided migration of cerebellar granule cell	1.000842e-4
GO:0043632	modification-dependent macromolecule catabolic process	1.030244e-4
GO:0051084	'de novo' posttranslational protein folding	1.031918e-4
GO:0007196	inhibition of adenylate cyclase activity by metabotropic glutamate receptor signaling pathway	1.125469e-4
GO:0072422	signal transduction involved in DNA damage checkpoint	1.163578e-4
GO:0045665	negative regulation of neuron differentiation	1.177859e-4
GO:0000082	G1/S transition of mitotic cell cycle	1.224444e-4
GO:0008298	intracellular mRNA localization	1.249552e-4
GO:0070127	tRNA aminoacylation for mitochondrial protein translation	1.288796e-4
GO:0007100	mitotic centrosome separation	1.293594e-4
GO:0070145	mitochondrial asparaginyl-tRNA aminoacylation	1.293594e-4
GO:0002474	antigen processing and presentation of peptide antigen via MHC class I	1.363583e-4
GO:0016070	RNA metabolic process	1.379327e-4
GO:0006807	nitrogen compound metabolic process	1.385474e-4
GO:0051208	sequestering of calcium ion	1.448068e-4
GO:0044257	cellular protein catabolic process	1.459986e-4
GO:0043551	regulation of phosphatidylinositol 3-kinase activity	1.526022e-4
GO:0006545	glycine biosynthetic process	1.535644e-4
GO:0043405	regulation of MAP kinase activity	1.599034e-4
GO:0070059	apoptosis in response to endoplasmic reticulum stress	1.681844e-4
GO:0072404	signal transduction involved in G1/S transition checkpoint	1.760995e-4
GO:0043951	negative regulation of cAMP-mediated signaling	1.820563e-4
GO:0007210	serotonin receptor signaling pathway	1.880208e-4
GO:0006683	galactosylceramide catabolic process	1.905022e-4
GO:0042026	protein refolding	1.933007e-4
GO:0031571	mitotic cell cycle G1/S transition DNA damage checkpoint	1.941989e-4
GO:0032851	positive regulation of Rab GTPase activity	1.998012e-4
GO:0021893	cerebral cortex GABAergic interneuron fate commitment	2.051213e-4
GO:0021882	regulation of transcription from RNA polymerase II promoter involved in forebrain neuron fate commitment	2.051213e-4
GO:0043653	mitochondrial fragmentation involved in apoptosis	2.198469e-4
GO:0072395	signal transduction involved in cell cycle checkpoint	2.216322e-4
GO:0000089	mitotic metaphase	2.280926e-4
GO:0071569	protein ufmylation	2.293506e-4
GO:0051900	regulation of mitochondrial depolarization	2.338260e-4
GO:0000216	M/G1 transition of mitotic cell cycle	2.451522e-4
GO:0019377	glycolipid catabolic process	2.478872e-4
GO:0015074	DNA integration	2.512836e-4
GO:0031397	negative regulation of protein ubiquitination	2.579351e-4
GO:0042770	signal transduction in response to DNA damage	2.613063e-4
GO:0043406	positive regulation of MAP kinase activity	2.651334e-4
GO:2000660	negative regulation of interleukin-1-mediated signaling pathway	2.687280e-4
GO:0046105	thymidine biosynthetic process	2.811801e-4
GO:0032232	negative regulation of actin filament bundle assembly	3.201466e-4
GO:0006677	glycosylceramide metabolic process	3.224222e-4
GO:0090218	positive regulation of lipid kinase activity	3.233686e-4
GO:0006260	DNA replication	3.256996e-4
GO:0042256	mature ribosome assembly	3.265500e-4
GO:0051865	protein autoubiquitination	3.400627e-4
GO:0031497	chromatin assembly	3.461317e-4
GO:0006551	leucine metabolic process	3.470317e-4
GO:0016072	rRNA metabolic process	3.762530e-4
GO:0071824	protein-DNA complex subunit organization	3.823163e-4
GO:0046929	negative regulation of neurotransmitter secretion	3.852250e-4
GO:0032964	collagen biosynthetic process	3.925308e-4
GO:0006189	'de novo' IMP biosynthetic process	3.929704e-4
GO:0034619	cellular chaperone-mediated protein complex assembly	4.056848e-4
GO:0007088	regulation of mitosis	4.208485e-4
GO:0008608	attachment of spindle microtubules to kinetochore	4.286505e-4
GO:0031055	chromatin remodeling at centromere	4.410187e-4
GO:0061351	neural precursor cell proliferation	4.592332e-4
GO:0001839	neural plate morphogenesis	4.734503e-4
GO:0010592	positive regulation of lamellipodium assembly	4.791807e-4
GO:0090068	positive regulation of cell cycle process	4.824007e-4
GO:0007049	cell cycle	5.174418e-4
GO:0006334	nucleosome assembly	5.273432e-4
GO:2000045	regulation of G1/S transition of mitotic cell cycle	5.291454e-4
GO:0000093	mitotic telophase	5.295338e-4
GO:0022617	extracellular matrix disassembly	5.405307e-4
GO:0015693	magnesium ion transport	5.405307e-4
GO:0022004	midbrain-hindbrain boundary maturation during brain development	5.420763e-4
GO:2000002	negative regulation of DNA damage checkpoint	5.420763e-4
GO:0021588	cerebellum formation	5.420763e-4
GO:0021551	central nervous system morphogenesis	5.420763e-4
GO:0009070	serine family amino acid biosynthetic process	5.455147e-4
GO:0006882	cellular zinc ion homeostasis	6.114135e-4
GO:0010800	positive regulation of peptidyl-threonine phosphorylation	6.400929e-4
GO:0051902	negative regulation of mitochondrial depolarization	6.615425e-4
GO:0045040	protein import into mitochondrial outer membrane	6.670486e-4
GO:0006086	acetyl-CoA biosynthetic process from pyruvate	6.738346e-4
GO:0007051	spindle organization	6.895308e-4
GO:0048103	somatic stem cell division	7.436786e-4
GO:0043271	negative regulation of ion transport	7.538367e-4
GO:0006853	carnitine shuttle	7.936351e-4
GO:0070543	response to linoleic acid	8.233449e-4
GO:0090007	regulation of mitotic anaphase	8.233449e-4
GO:0034696	response to prostaglandin F stimulus	8.233449e-4
GO:0031120	snRNA pseudouridine synthesis	8.233449e-4
GO:0006361	transcription initiation from RNA polymerase I promoter	8.644602e-4
GO:0043029	T cell homeostasis	8.789659e-4
GO:0046104	thymidine metabolic process	8.882684e-4
GO:0032912	negative regulation of transforming growth factor beta2 production	9.463575e-4
GO:0070925	organelle assembly	9.764671e-4
GO:0006661	phosphatidylinositol biosynthetic process	9.768779e-4
GO:0031122	cytoplasmic microtubule organization	9.777363e-4
GO:0051154	negative regulation of striated muscle cell differentiation	1.033480e-3
GO:0048385	regulation of retinoic acid receptor signaling pathway	1.071250e-3
GO:0042398	cellular modified amino acid biosynthetic process	1.073803e-3
GO:0042273	ribosomal large subunit biogenesis	1.078439e-3
GO:0030219	megakaryocyte differentiation	1.078439e-3
GO:0006974	response to DNA damage stimulus	1.084800e-3
GO:0042989	sequestering of actin monomers	1.091918e-3
GO:2000249	regulation of actin cytoskeleton reorganization	1.101725e-3
GO:0014041	regulation of neuron maturation	1.110223e-3
GO:0061101	neuroendocrine cell differentiation	1.111701e-3
GO:0035372	protein localization to microtubule	1.111701e-3
GO:0060263	regulation of respiratory burst	1.148932e-3
GO:0006261	DNA-dependent DNA replication	1.155035e-3
GO:0006600	creatine metabolic process	1.195694e-3
GO:0051583	dopamine uptake	1.298866e-3
GO:0000375	RNA splicing, via transesterification reactions	1.310621e-3
GO:0015761	mannose transport	1.364680e-3
GO:0006369	termination of RNA polymerase II transcription	1.372143e-3
GO:0006379	mRNA cleavage	1.373634e-3
GO:0006513	protein monoubiquitination	1.385501e-3
GO:0043128	positive regulation of 1-phosphatidylinositol 4-kinase activity	1.395355e-3
GO:0000398	nuclear mRNA splicing, via spliceosome	1.402750e-3
GO:0001843	neural tube closure	1.409598e-3
GO:0006110	regulation of glycolysis	1.419149e-3
GO:0019376	galactolipid catabolic process	1.432662e-3
GO:0032543	mitochondrial translation	1.438159e-3
GO:0071502	cellular response to temperature stimulus	1.509774e-3
GO:0072272	proximal/distal pattern formation involved in metanephric nephron development	1.541792e-3
GO:0007521	muscle cell fate determination	1.569744e-3
GO:0009057	macromolecule catabolic process	1.662123e-3
GO:0071279	cellular response to cobalt ion	1.666850e-3
GO:0010637	negative regulation of mitochondrial fusion	1.666850e-3
GO:0032074	negative regulation of nuclease activity	1.666850e-3
GO:0010834	telomere maintenance via telomere shortening	1.668964e-3
GO:0060606	tube closure	1.735013e-3
GO:0006188	IMP biosynthetic process	1.746419e-3
GO:0045204	MAPK export from nucleus	1.773787e-3
GO:0045209	MAPK phosphatase export from nucleus, leptomycin B sensitive	1.773787e-3
GO:0009794	regulation of mitotic cell cycle, embryonic	1.780673e-3
GO:0045792	negative regulation of cell size	1.793423e-3
GO:0048742	regulation of skeletal muscle fiber development	1.819459e-3
GO:0009069	serine family amino acid metabolic process	1.898508e-3
GO:0007127	meiosis I	1.922188e-3
GO:0085020	protein K6-linked ubiquitination	1.973363e-3
GO:0032066	nucleolus to nucleoplasm transport	1.981431e-3
GO:0060947	cardiac vascular smooth muscle cell differentiation	2.010862e-3
GO:0016180	snRNA processing	2.060556e-3
GO:0060136	embryonic process involved in female pregnancy	2.082312e-3
GO:0014020	primary neural tube formation	2.086799e-3
GO:0038007	netrin-activated signaling pathway	2.167340e-3
GO:0070842	aggresome assembly	2.190444e-3
GO:0031054	pre-miRNA processing	2.228045e-3
GO:0051661	maintenance of centrosome location	2.255904e-3
GO:2000781	positive regulation of double-strand break repair	2.313127e-3
GO:0019068	virion assembly	2.313127e-3
GO:0030163	protein catabolic process	2.321667e-3
GO:0043375	CD8-positive, alpha-beta T cell lineage commitment	2.330305e-3
GO:0032848	negative regulation of cellular pH reduction	2.330305e-3
GO:0014042	positive regulation of neuron maturation	2.330305e-3
GO:0021747	cochlear nucleus development	2.330305e-3
GO:0006363	termination of RNA polymerase I transcription	2.332465e-3
GO:0051926	negative regulation of calcium ion transport	2.402379e-3
GO:0051131	chaperone-mediated protein complex assembly	2.402941e-3
GO:0021915	neural tube development	2.403793e-3
GO:0046514	ceramide catabolic process	2.471442e-3
GO:0071900	regulation of protein serine/threonine kinase activity	2.609889e-3
GO:0048246	macrophage chemotaxis	2.636799e-3
GO:0009106	lipoate metabolic process	2.736566e-3
GO:0009726	detection of endogenous stimulus	2.843238e-3
GO:0035307	positive regulation of protein dephosphorylation	2.843626e-3
GO:0046732	active induction of host immune response by virus	2.867535e-3
GO:0001776	leukocyte homeostasis	2.903535e-3
GO:0034501	protein localization to kinetochore	2.919403e-3
GO:0070936	protein K48-linked ubiquitination	2.965868e-3
GO:0061144	alveolar secondary septum development	2.973986e-3
GO:0046668	regulation of retinal cell programmed cell death	3.012741e-3
GO:0051324	prophase	3.026511e-3
GO:0010823	negative regulation of mitochondrion organization	3.043111e-3
GO:0019229	regulation of vasoconstriction	3.081652e-3
GO:0034115	negative regulation of heterotypic cell-cell adhesion	3.105170e-3
GO:0032730	positive regulation of interleukin-1 alpha production	3.186227e-3
GO:0060019	radial glial cell differentiation	3.194372e-3
GO:0072364	regulation of cellular ketone metabolic process by regulation of transcription from RNA polymerase II promoter	3.240306e-3
GO:0060659	nipple sheath formation	3.389934e-3
GO:0090035	positive regulation of cellular chaperone-mediated protein complex assembly	3.389934e-3
GO:0060649	mammary gland bud elongation	3.389934e-3
GO:0009786	regulation of asymmetric cell division	3.498548e-3
GO:0008057	eye pigment granule organization	3.498548e-3
GO:0035306	positive regulation of dephosphorylation	3.516230e-3
GO:0046125	pyrimidine deoxyribonucleoside metabolic process	3.576717e-3
GO:0090272	negative regulation of fibroblast growth factor production	3.584937e-3
GO:0006808	regulation of nitrogen utilization	3.618366e-3
GO:0019388	galactose catabolic process	3.618366e-3
GO:0002260	lymphocyte homeostasis	3.653641e-3
GO:0010523	negative regulation of calcium ion transport into cytosol	3.677592e-3
GO:0010591	regulation of lamellipodium assembly	3.696934e-3
GO:0070534	protein K63-linked ubiquitination	3.831621e-3
GO:0006337	nucleosome disassembly	3.864035e-3
GO:2000725	regulation of cardiac muscle cell differentiation	3.914285e-3
GO:0051168	nuclear export	3.933425e-3
GO:0006681	galactosylceramide metabolic process	3.995111e-3
GO:0046730	induction of host immune response by virus	4.007458e-3
GO:0006085	acetyl-CoA biosynthetic process	4.013078e-3
GO:0009059	macromolecule biosynthetic process	4.050445e-3
GO:0001840	neural plate development	4.149591e-3
GO:0006325	chromatin organization	4.161501e-3
GO:0006259	DNA metabolic process	4.218995e-3
GO:0043496	regulation of protein homodimerization activity	4.239568e-3
GO:0071812	positive regulation of fever generation by positive regulation of prostaglandin secretion	4.303996e-3
GO:0071848	positive regulation of ERK1 and ERK2 cascade via TNFSF11-mediated signaling	4.303996e-3
GO:0043552	positive regulation of phosphatidylinositol 3-kinase activity	4.311676e-3
GO:0002052	positive regulation of neuroblast proliferation	4.315862e-3
GO:0072393	microtubule anchoring at microtubule organizing center	4.333889e-3
GO:0034112	positive regulation of homotypic cell-cell adhesion	4.440153e-3
GO:2000348	regulation of CD40 signaling pathway	4.459670e-3
GO:0055069	zinc ion homeostasis	4.459670e-3
GO:0051153	regulation of striated muscle cell differentiation	4.602112e-3
GO:0006360	transcription from RNA polymerase I promoter	4.654058e-3
GO:0046671	negative regulation of retinal cell programmed cell death	4.691021e-3
GO:0072385	minus-end-directed organelle transport along microtubule	4.694887e-3
GO:0042249	establishment of planar polarity of embryonic epithelium	4.825378e-3
GO:0006780	uroporphyrinogen III biosynthetic process	4.847229e-3
GO:0035519	protein K29-linked ubiquitination	4.866604e-3
GO:0000463	maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)	4.866604e-3
GO:0001841	neural tube formation	4.873617e-3
GO:0051313	attachment of spindle microtubules to chromosome	4.883195e-3
GO:0003300	cardiac muscle hypertrophy	4.913959e-3
GO:0060045	positive regulation of cardiac muscle cell proliferation	5.034605e-3
GO:0030579	ubiquitin-dependent SMAD protein catabolic process	5.079082e-3
GO:0048002	antigen processing and presentation of peptide antigen	5.147669e-3
GO:0045769	negative regulation of asymmetric cell division	5.209147e-3
GO:0071277	cellular response to calcium ion	5.278631e-3
GO:0033326	cerebrospinal fluid secretion	5.392869e-3
GO:0007497	posterior midgut development	5.392869e-3
GO:0034436	glycoprotein transport	5.549314e-3
GO:0009720	detection of hormone stimulus	5.549314e-3
GO:0032741	positive regulation of interleukin-18 production	5.572074e-3
GO:0070371	ERK1 and ERK2 cascade	5.584113e-3
GO:0030330	DNA damage response, signal transduction by p53 class mediator	5.613068e-3
GO:0044314	protein K27-linked ubiquitination	5.827855e-3
GO:2000587	negative regulation of platelet-derived growth factor receptor-beta signaling pathway	5.827855e-3
GO:0001988	positive regulation of heart rate involved in baroreceptor response to decreased systemic arterial blood pressure	5.827855e-3
GO:0071635	negative regulation of transforming growth factor beta production	5.921046e-3
GO:0008612	peptidyl-lysine modification to hypusine	5.932556e-3
GO:0017145	stem cell division	5.950290e-3
GO:0001808	negative regulation of type IV hypersensitivity	6.026000e-3
GO:2000786	positive regulation of autophagic vacuole assembly	6.026000e-3
GO:0043486	histone exchange	6.027282e-3
GO:0006564	L-serine biosynthetic process	6.057901e-3
GO:0003254	regulation of membrane depolarization	6.286836e-3
GO:0000084	S phase of mitotic cell cycle	6.303145e-3
GO:0046605	regulation of centrosome cycle	6.393100e-3
GO:0021932	hindbrain radial glia guided cell migration	6.459782e-3
GO:0010508	positive regulation of autophagy	6.459782e-3
GO:0046521	sphingoid catabolic process	6.522673e-3
GO:0021873	forebrain neuroblast division	6.554454e-3
GO:0006298	mismatch repair	6.717425e-3
GO:0071374	cellular response to parathyroid hormone stimulus	6.781059e-3
GO:0006281	DNA repair	6.809423e-3
GO:0007216	metabotropic glutamate receptor signaling pathway	6.867874e-3
GO:0034349	glial cell apoptosis	6.867874e-3
GO:0044260	cellular macromolecule metabolic process	6.884497e-3
GO:0060025	regulation of synaptic activity	6.910149e-3
GO:0006338	chromatin remodeling	6.987967e-3
GO:0051466	positive regulation of corticotropin-releasing hormone secretion	7.120470e-3
GO:0045618	positive regulation of keratinocyte differentiation	7.120798e-3
GO:2000727	positive regulation of cardiac muscle cell differentiation	7.126714e-3
GO:2000987	positive regulation of behavioral fear response	7.126714e-3
GO:0003185	sinoatrial valve morphogenesis	7.126714e-3
GO:0035984	cellular response to trichostatin A	7.126714e-3
GO:0003138	primary heart field specification	7.126714e-3
GO:0021903	rostrocaudal neural tube patterning	7.142464e-3
GO:0016574	histone ubiquitination	7.158492e-3
GO:0046604	positive regulation of mitotic centrosome separation	7.209320e-3
GO:0007161	calcium-independent cell-matrix adhesion	7.209320e-3
GO:0007057	spindle assembly involved in female meiosis I	7.209320e-3
GO:0000188	inactivation of MAPK activity	7.273527e-3
GO:0060430	lung saccule development	7.342069e-3
GO:0051320	S phase	7.364830e-3
GO:0034635	glutathione transport	7.380857e-3
GO:0001807	regulation of type IV hypersensitivity	7.380857e-3
GO:0009107	lipoate biosynthetic process	7.380857e-3
GO:0051782	negative regulation of cell division	7.396359e-3
GO:0060282	positive regulation of oocyte development	7.712360e-3
GO:0010625	positive regulation of Schwann cell proliferation	7.712360e-3
GO:0045132	meiotic chromosome segregation	7.772550e-3
GO:0048247	lymphocyte chemotaxis	7.840571e-3
GO:0060061	Spemann organizer formation	7.881991e-3
GO:0048671	negative regulation of collateral sprouting	7.884170e-3
GO:0006435	threonyl-tRNA aminoacylation	8.172675e-3
GO:0060534	trachea cartilage development	8.333951e-3
GO:0045606	positive regulation of epidermal cell differentiation	8.333951e-3
GO:0043506	regulation of JUN kinase activity	8.339496e-3
GO:0065004	protein-DNA complex assembly	8.396179e-3
GO:0045986	negative regulation of smooth muscle contraction	8.480091e-3
GO:0051280	negative regulation of release of sequestered calcium ion into cytosol	8.480091e-3
GO:0009817	defense response to fungus, incompatible interaction	8.480091e-3
GO:0051972	regulation of telomerase activity	8.543132e-3
GO:0043044	ATP-dependent chromatin remodeling	8.639617e-3
GO:0001955	blood vessel maturation	8.691131e-3
GO:0045793	positive regulation of cell size	8.835325e-3
GO:0006007	glucose catabolic process	8.897417e-3
GO:0032214	negative regulation of telomere maintenance via semi-conservative replication	8.921880e-3
GO:0001309	age-dependent telomere shortening	8.921880e-3
GO:2000059	negative regulation of protein ubiquitination involved in ubiquitin-dependent protein catabolic process	8.989975e-3
GO:0046952	ketone body catabolic process	8.989975e-3
GO:0010700	negative regulation of norepinephrine secretion	8.992837e-3
GO:0060489	planar dichotomous subdivision of terminal units involved in lung branching morphogenesis	9.076804e-3
GO:0060490	lateral sprouting involved in lung morphogenesis	9.076804e-3
GO:0060488	orthogonal dichotomous subdivision of terminal units involved in lung branching morphogenesis	9.076804e-3
GO:0002051	osteoblast fate commitment	9.076804e-3
GO:0009440	cyanate catabolic process	9.076804e-3
GO:0048105	establishment of body hair planar orientation	9.076804e-3
GO:0071902	positive regulation of protein serine/threonine kinase activity	9.148127e-3
GO:0016568	chromatin modification	9.149678e-3
GO:0002439	chronic inflammatory response to antigenic stimulus	9.302796e-3
GO:0034645	cellular macromolecule biosynthetic process	9.379312e-3
GO:0032367	intracellular cholesterol transport	9.534579e-3
GO:0070159	mitochondrial threonyl-tRNA aminoacylation	9.604060e-3
GO:0045661	regulation of myoblast differentiation	9.858547e-3
GO:0007285	primary spermatocyte growth	1.009253e-2
GO:0001731	formation of translation preinitiation complex	1.009253e-2
GO:0006403	RNA localization	1.009437e-2
GO:0010948	negative regulation of cell cycle process	1.022296e-2
GO:0000090	mitotic anaphase	1.022730e-2
GO:0051497	negative regulation of stress fiber assembly	1.027147e-2
GO:0051409	response to nitrosative stress	1.028516e-2
GO:0003333	amino acid transmembrane transport	1.034719e-2
GO:0051329	interphase of mitotic cell cycle	1.034835e-2
GO:0051169	nuclear transport	1.041660e-2
GO:0019374	galactolipid metabolic process	1.042094e-2
GO:0051640	organelle localization	1.054809e-2
GO:0034498	early endosome to Golgi transport	1.065837e-2
GO:0090075	relaxation of muscle	1.070794e-2
GO:0043949	regulation of cAMP-mediated signaling	1.070794e-2
GO:0045343	regulation of MHC class I biosynthetic process	1.078377e-2
GO:0031536	positive regulation of exit from mitosis	1.078659e-2
GO:0006839	mitochondrial transport	1.081284e-2
GO:0008652	cellular amino acid biosynthetic process	1.101820e-2
GO:0006364	rRNA processing	1.114539e-2
GO:0010799	regulation of peptidyl-threonine phosphorylation	1.121747e-2
GO:0048743	positive regulation of skeletal muscle fiber development	1.136345e-2
GO:0060364	frontal suture morphogenesis	1.164011e-2
GO:0001958	endochondral ossification	1.172486e-2
GO:0032740	positive regulation of interleukin-17 production	1.175427e-2
GO:0090118	receptor-mediated endocytosis of low-density lipoprotein particle involved in cholesterol transport	1.182909e-2
GO:0060112	generation of ovulation cycle rhythm	1.182909e-2
GO:0016241	regulation of macroautophagy	1.182909e-2
GO:0043471	regulation of cellular carbohydrate catabolic process	1.216368e-2
GO:0010826	negative regulation of centrosome duplication	1.240749e-2
GO:0035645	enteric smooth muscle cell differentiation	1.241507e-2
GO:0071228	cellular response to tumor cell	1.259882e-2
GO:0090251	protein localization involved in establishment of planar polarity	1.259882e-2
GO:0019402	galactitol metabolic process	1.259882e-2
GO:0044088	regulation of vacuole organization	1.259882e-2
GO:0002865	negative regulation of acute inflammatory response to antigenic stimulus	1.259882e-2
GO:0006096	glycolysis	1.279552e-2
GO:0007522	visceral muscle development	1.283681e-2
GO:0003310	pancreatic A cell differentiation	1.288323e-2
GO:0060648	mammary gland bud morphogenesis	1.289399e-2
GO:0045907	positive regulation of vasoconstriction	1.301189e-2
GO:0006359	regulation of transcription from RNA polymerase III promoter	1.316761e-2
GO:0001782	B cell homeostasis	1.332276e-2
GO:0045663	positive regulation of myoblast differentiation	1.334225e-2
GO:0014065	phosphatidylinositol 3-kinase cascade	1.338208e-2
GO:0051325	interphase	1.338969e-2
GO:0090009	primitive streak formation	1.354388e-2

GREAT analysis results for mouseGenomic Enrichment of Annotations Tool (GREAT, Nat Biotechnol. 2010 May;28(5):495-501) is used to identify, both in human and in mouse, the gene ontology terms of biological processes enriched given the predicted TFBSs, and evaluated the overlap in the top-500 gene ontology terms between human and mouse. For each novel motif, the P value for the overlap was then evaluated by calculating its relative rank with respect to this background distribution.<br>Analyst: Michiel de Hoon <br><br>link to source dataset <br>data

---

GO ID	GO Term	p-value
GO:0016139	glycoside catabolic process	5.636723e-10
GO:0042069	regulation of catecholamine metabolic process	1.188270e-9
GO:0042053	regulation of dopamine metabolic process	2.063665e-9
GO:0060659	nipple sheath formation	3.328922e-9
GO:0060649	mammary gland bud elongation	3.328922e-9
GO:0033238	regulation of cellular amine metabolic process	8.165563e-9
GO:0009992	cellular water homeostasis	1.517956e-8
GO:0032872	regulation of stress-activated MAPK cascade	2.500505e-8
GO:0042424	catecholamine catabolic process	3.702186e-8
GO:0070831	basement membrane assembly	4.395899e-8
GO:0050668	positive regulation of homocysteine metabolic process	9.039334e-8
GO:0045963	negative regulation of dopamine metabolic process	9.039334e-8
GO:0071286	cellular response to magnesium ion	9.651755e-8
GO:0016137	glycoside metabolic process	1.910529e-7
GO:0016142	O-glycoside catabolic process	1.978288e-7
GO:0072355	histone H3-T3 phosphorylation	2.332687e-7
GO:0033240	positive regulation of cellular amine metabolic process	3.673654e-7
GO:0008334	histone mRNA metabolic process	3.791978e-7
GO:0000305	response to oxygen radical	3.853878e-7
GO:0042420	dopamine catabolic process	5.028711e-7
GO:0060658	nipple morphogenesis	5.975538e-7
GO:0015876	acetyl-CoA transport	6.725010e-7
GO:0061136	regulation of proteasomal protein catabolic process	6.782918e-7
GO:0060264	regulation of respiratory burst involved in inflammatory response	9.946081e-7
GO:0019285	glycine betaine biosynthetic process from choline	9.946081e-7
GO:0021568	rhombomere 2 development	9.946081e-7
GO:2000729	positive regulation of mesenchymal cell proliferation involved in ureter development	1.197730e-6
GO:0032434	regulation of proteasomal ubiquitin-dependent protein catabolic process	1.540234e-6
GO:0007064	mitotic sister chromatid cohesion	1.873671e-6
GO:0030038	contractile actin filament bundle assembly	1.912954e-6
GO:0035912	dorsal aorta morphogenesis	1.912954e-6
GO:0051438	regulation of ubiquitin-protein ligase activity	2.853742e-6
GO:0071044	histone mRNA catabolic process	2.889785e-6
GO:0007059	chromosome segregation	3.397670e-6
GO:0016140	O-glycoside metabolic process	3.844799e-6
GO:0090398	cellular senescence	4.040307e-6
GO:0048680	positive regulation of axon regeneration	4.503209e-6
GO:0072079	nephron tubule formation	5.067329e-6
GO:0008652	cellular amino acid biosynthetic process	5.761632e-6
GO:0031331	positive regulation of cellular catabolic process	5.995410e-6
GO:0042428	serotonin metabolic process	6.286362e-6
GO:0090399	replicative senescence	6.617400e-6
GO:0045764	positive regulation of cellular amino acid metabolic process	6.900397e-6
GO:0060648	mammary gland bud morphogenesis	6.900397e-6
GO:0032873	negative regulation of stress-activated MAPK cascade	6.900397e-6
GO:0046477	glycosylceramide catabolic process	7.310216e-6
GO:0042417	dopamine metabolic process	8.020702e-6
GO:0033314	mitotic cell cycle DNA replication checkpoint	9.864016e-6
GO:0048285	organelle fission	1.020272e-5
GO:0007569	cell aging	1.400976e-5
GO:0030104	water homeostasis	1.570020e-5
GO:0060045	positive regulation of cardiac muscle cell proliferation	1.631256e-5
GO:0060263	regulation of respiratory burst	1.702242e-5
GO:0000413	protein peptidyl-prolyl isomerization	1.756890e-5
GO:0051340	regulation of ligase activity	1.756890e-5
GO:0060266	negative regulation of respiratory burst involved in inflammatory response	1.882697e-5
GO:0051451	myoblast migration	1.905009e-5
GO:0051176	positive regulation of sulfur metabolic process	1.905009e-5
GO:0048291	isotype switching to IgG isotypes	2.089362e-5
GO:0002368	B cell cytokine production	2.089362e-5
GO:0072513	positive regulation of secondary heart field cardioblast proliferation	2.315154e-5
GO:0006102	isocitrate metabolic process	2.315154e-5
GO:0090231	regulation of spindle checkpoint	2.451468e-5
GO:0031570	DNA integrity checkpoint	2.514272e-5
GO:0071248	cellular response to metal ion	2.632965e-5
GO:0021930	cerebellar granule cell precursor proliferation	2.712389e-5
GO:0051439	regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle	2.748918e-5
GO:0072086	specification of loop of Henle identity	2.748918e-5
GO:0070303	negative regulation of stress-activated protein kinase signaling cascade	2.753297e-5
GO:0071711	basement membrane organization	2.854965e-5
GO:0000070	mitotic sister chromatid segregation	2.883786e-5
GO:0007067	mitosis	3.004348e-5
GO:0061333	renal tubule morphogenesis	3.215050e-5
GO:0006978	DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator	3.377805e-5
GO:0043149	stress fiber assembly	3.490565e-5
GO:0060947	cardiac vascular smooth muscle cell differentiation	3.490565e-5
GO:0001947	heart looping	3.835436e-5
GO:0060213	positive regulation of nuclear-transcribed mRNA poly(A) tail shortening	3.983810e-5
GO:0060347	heart trabecula formation	4.584388e-5
GO:0007379	segment specification	4.591130e-5
GO:0072199	regulation of mesenchymal cell proliferation involved in ureter development	4.671223e-5
GO:0072272	proximal/distal pattern formation involved in metanephric nephron development	4.857050e-5
GO:0000087	M phase of mitotic cell cycle	5.249764e-5
GO:0010735	positive regulation of transcription via serum response element binding	5.275826e-5
GO:0000077	DNA damage checkpoint	5.276762e-5
GO:0051443	positive regulation of ubiquitin-protein ligase activity	5.851532e-5
GO:0070830	tight junction assembly	6.371134e-5
GO:0018208	peptidyl-proline modification	6.888647e-5
GO:0072592	oxygen metabolic process	7.215522e-5
GO:0006578	betaine biosynthetic process	7.463743e-5
GO:0031663	lipopolysaccharide-mediated signaling pathway	7.464544e-5
GO:0006974	response to DNA damage stimulus	8.366501e-5
GO:0000819	sister chromatid segregation	8.511648e-5
GO:0019430	removal of superoxide radicals	8.983658e-5
GO:0033561	regulation of water loss via skin	9.544912e-5
GO:0032312	regulation of ARF GTPase activity	9.560330e-5
GO:0042772	DNA damage response, signal transduction resulting in transcription	1.036576e-4
GO:0031585	regulation of inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity	1.040433e-4
GO:0061351	neural precursor cell proliferation	1.124674e-4
GO:0042218	1-aminocyclopropane-1-carboxylate biosynthetic process	1.170566e-4
GO:0006710	androgen catabolic process	1.195731e-4
GO:0090073	positive regulation of protein homodimerization activity	1.247186e-4
GO:0032874	positive regulation of stress-activated MAPK cascade	1.247186e-4
GO:0031572	G2/M transition DNA damage checkpoint	1.258322e-4
GO:2000781	positive regulation of double-strand break repair	1.358003e-4
GO:0060816	random inactivation of X chromosome	1.358003e-4
GO:0006666	3-keto-sphinganine metabolic process	1.358003e-4
GO:0006409	tRNA export from nucleus	1.358003e-4
GO:0072081	specification of nephron tubule identity	1.403771e-4
GO:0043950	positive regulation of cAMP-mediated signaling	1.461824e-4
GO:0019370	leukotriene biosynthetic process	1.540502e-4
GO:0031440	regulation of mRNA 3'-end processing	1.587109e-4
GO:0043508	negative regulation of JUN kinase activity	1.587109e-4
GO:0051145	smooth muscle cell differentiation	1.756466e-4
GO:0071287	cellular response to manganese ion	1.864877e-4
GO:0032057	negative regulation of translational initiation in response to stress	1.869810e-4
GO:0031442	positive regulation of mRNA 3'-end processing	1.869972e-4
GO:0032435	negative regulation of proteasomal ubiquitin-dependent protein catabolic process	1.920580e-4
GO:0042398	cellular modified amino acid biosynthetic process	1.984956e-4
GO:0009309	amine biosynthetic process	1.994354e-4
GO:0006189	'de novo' IMP biosynthetic process	2.007634e-4
GO:0001975	response to amphetamine	2.022188e-4
GO:0010902	positive regulation of very-low-density lipoprotein particle remodeling	2.026150e-4
GO:0051436	negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle	2.084210e-4
GO:0001964	startle response	2.326787e-4
GO:0043496	regulation of protein homodimerization activity	2.445737e-4
GO:0019858	cytosine metabolic process	2.617365e-4
GO:0006449	regulation of translational termination	2.639386e-4
GO:0045652	regulation of megakaryocyte differentiation	2.641050e-4
GO:0048143	astrocyte activation	2.679232e-4
GO:0071474	cellular hyperosmotic response	2.702192e-4
GO:0002352	B cell negative selection	2.702192e-4
GO:0042135	neurotransmitter catabolic process	2.785786e-4
GO:0015732	prostaglandin transport	2.799072e-4
GO:0060012	synaptic transmission, glycinergic	2.799072e-4
GO:0035886	vascular smooth muscle cell differentiation	2.878710e-4
GO:0006691	leukotriene metabolic process	2.924812e-4
GO:0048854	brain morphogenesis	2.965815e-4
GO:0000303	response to superoxide	2.986894e-4
GO:0046394	carboxylic acid biosynthetic process	3.038094e-4
GO:0032012	regulation of ARF protein signal transduction	3.053992e-4
GO:0007093	mitotic cell cycle checkpoint	3.053992e-4
GO:0046329	negative regulation of JNK cascade	3.072868e-4
GO:0060081	membrane hyperpolarization	3.072868e-4
GO:0072107	positive regulation of ureteric bud formation	3.141159e-4
GO:0060359	response to ammonium ion	3.236436e-4
GO:0030050	vesicle transport along actin filament	3.236436e-4
GO:0071158	positive regulation of cell cycle arrest	3.293454e-4
GO:0019087	transformation of host cell by virus	3.307472e-4
GO:0006361	transcription initiation from RNA polymerase I promoter	3.307472e-4
GO:0044241	lipid digestion	3.365804e-4
GO:0043032	positive regulation of macrophage activation	3.558667e-4
GO:0000076	DNA replication checkpoint	3.572226e-4
GO:0007057	spindle assembly involved in female meiosis I	3.672384e-4
GO:0072078	nephron tubule morphogenesis	3.704615e-4
GO:0071156	regulation of cell cycle arrest	3.794885e-4
GO:0030220	platelet formation	3.858510e-4
GO:0060075	regulation of resting membrane potential	3.909348e-4
GO:0060409	positive regulation of acetylcholine metabolic process	4.040702e-4
GO:0002541	activation of plasma proteins involved in acute inflammatory response	4.040702e-4
GO:2000111	positive regulation of macrophage apoptosis	4.084082e-4
GO:0032471	reduction of endoplasmic reticulum calcium ion concentration	4.084082e-4
GO:0045081	negative regulation of interleukin-10 biosynthetic process	4.104499e-4
GO:0007256	activation of JNKK activity	4.283998e-4
GO:0006982	response to lipid hydroperoxide	4.556228e-4
GO:0000089	mitotic metaphase	4.646806e-4
GO:0055021	regulation of cardiac muscle tissue growth	4.771626e-4
GO:0090009	primitive streak formation	5.076053e-4
GO:0006289	nucleotide-excision repair	5.090318e-4
GO:0000279	M phase	5.145806e-4
GO:0006586	indolalkylamine metabolic process	5.441864e-4
GO:0051351	positive regulation of ligase activity	5.441864e-4
GO:0061180	mammary gland epithelium development	5.760795e-4
GO:0043297	apical junction assembly	5.836245e-4
GO:0061014	positive regulation of mRNA catabolic process	5.929412e-4
GO:0042176	regulation of protein catabolic process	6.055919e-4
GO:0072268	pattern specification involved in metanephros development	6.155729e-4
GO:0034619	cellular chaperone-mediated protein complex assembly	6.155729e-4
GO:0072080	nephron tubule development	6.317048e-4
GO:0006584	catecholamine metabolic process	6.570605e-4
GO:0061004	pattern specification involved in kidney development	6.583790e-4
GO:0061384	heart trabecular morphogenesis	6.635723e-4
GO:0044283	small molecule biosynthetic process	6.739440e-4
GO:0048645	organ formation	6.834707e-4
GO:0009896	positive regulation of catabolic process	6.875365e-4
GO:0072172	mesonephric tubule formation	6.982037e-4
GO:0071879	positive regulation of adrenergic receptor signaling pathway	7.293443e-4
GO:0050717	positive regulation of interleukin-1 alpha secretion	7.293443e-4
GO:0061052	negative regulation of cell growth involved in cardiac muscle cell development	7.293443e-4
GO:0051602	response to electrical stimulus	7.476280e-4
GO:0048050	post-embryonic eye morphogenesis	7.612262e-4
GO:0009083	branched chain family amino acid catabolic process	7.699782e-4
GO:0048538	thymus development	7.993622e-4
GO:0072095	regulation of branch elongation involved in ureteric bud branching	8.083032e-4
GO:0014002	astrocyte development	8.528670e-4
GO:0042443	phenylethylamine metabolic process	8.867556e-4
GO:0051793	medium-chain fatty acid catabolic process	8.867556e-4
GO:0060025	regulation of synaptic activity	8.905641e-4
GO:2000987	positive regulation of behavioral fear response	8.905641e-4
GO:0035984	cellular response to trichostatin A	8.905641e-4
GO:0003185	sinoatrial valve morphogenesis	8.905641e-4
GO:0003138	primary heart field specification	8.905641e-4
GO:0007030	Golgi organization	9.095025e-4
GO:0045905	positive regulation of translational termination	9.421802e-4
GO:0006452	translational frameshifting	9.421802e-4
GO:0045901	positive regulation of translational elongation	9.421802e-4
GO:0021761	limbic system development	9.731978e-4
GO:0021782	glial cell development	9.859667e-4
GO:0070302	regulation of stress-activated protein kinase signaling cascade	1.009393e-3
GO:0016567	protein ubiquitination	1.011673e-3
GO:0006977	DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest	1.013904e-3
GO:0009148	pyrimidine nucleoside triphosphate biosynthetic process	1.014700e-3
GO:0031576	G2/M transition checkpoint	1.027017e-3
GO:0006463	steroid hormone receptor complex assembly	1.033621e-3
GO:0007096	regulation of exit from mitosis	1.053837e-3
GO:0000075	cell cycle checkpoint	1.101811e-3
GO:0006235	dTTP biosynthetic process	1.104691e-3
GO:0044088	regulation of vacuole organization	1.104691e-3
GO:0042744	hydrogen peroxide catabolic process	1.115256e-3
GO:0051276	chromosome organization	1.124609e-3
GO:0003207	cardiac chamber formation	1.151783e-3
GO:0051643	endoplasmic reticulum localization	1.164884e-3
GO:0048597	post-embryonic camera-type eye morphogenesis	1.164884e-3
GO:0071241	cellular response to inorganic substance	1.178504e-3
GO:0032436	positive regulation of proteasomal ubiquitin-dependent protein catabolic process	1.192182e-3
GO:0006734	NADH metabolic process	1.208322e-3
GO:0061326	renal tubule development	1.248920e-3
GO:0010922	positive regulation of phosphatase activity	1.280890e-3
GO:0006414	translational elongation	1.281665e-3
GO:0009147	pyrimidine nucleoside triphosphate metabolic process	1.307283e-3
GO:0048701	embryonic cranial skeleton morphogenesis	1.320292e-3
GO:0034498	early endosome to Golgi transport	1.342828e-3
GO:0055090	acylglycerol homeostasis	1.356456e-3
GO:0045019	negative regulation of nitric oxide biosynthetic process	1.378756e-3
GO:0033599	regulation of mammary gland epithelial cell proliferation	1.439076e-3
GO:0003179	heart valve morphogenesis	1.523143e-3
GO:0071374	cellular response to parathyroid hormone stimulus	1.523491e-3
GO:0006281	DNA repair	1.540093e-3
GO:0072422	signal transduction involved in DNA damage checkpoint	1.556616e-3
GO:0014898	cardiac muscle hypertrophy in response to stress	1.566904e-3
GO:0002309	T cell proliferation involved in immune response	1.582610e-3
GO:0034470	ncRNA processing	1.588964e-3
GO:0019287	isopentenyl diphosphate biosynthetic process, mevalonate pathway	1.597250e-3
GO:0003211	cardiac ventricle formation	1.637639e-3
GO:0046491	L-methylmalonyl-CoA metabolic process	1.713114e-3
GO:0001879	detection of yeast	1.713114e-3
GO:0032510	endosome to lysosome transport via multivesicular body sorting pathway	1.723516e-3
GO:0010972	negative regulation of G2/M transition of mitotic cell cycle	1.728816e-3
GO:0030431	sleep	1.784544e-3
GO:0048708	astrocyte differentiation	1.787056e-3
GO:0014050	negative regulation of glutamate secretion	1.809596e-3
GO:2000109	regulation of macrophage apoptosis	1.846906e-3
GO:0010042	response to manganese ion	1.866679e-3
GO:0016572	histone phosphorylation	1.918396e-3
GO:0034626	fatty acid elongation, polyunsaturated fatty acid	1.933467e-3
GO:0021546	rhombomere development	1.933467e-3
GO:0018027	peptidyl-lysine dimethylation	1.937706e-3
GO:0002227	innate immune response in mucosa	1.937706e-3
GO:0048679	regulation of axon regeneration	1.990737e-3
GO:0034644	cellular response to UV	2.005718e-3
GO:0010092	specification of organ identity	2.059114e-3
GO:0071459	protein localization to chromosome, centromeric region	2.078333e-3
GO:0043517	positive regulation of DNA damage response, signal transduction by p53 class mediator	2.078333e-3
GO:0060847	endothelial cell fate specification	2.083294e-3
GO:0046328	regulation of JNK cascade	2.133819e-3
GO:0046856	phosphatidylinositol dephosphorylation	2.141064e-3
GO:0006577	betaine metabolic process	2.154709e-3
GO:0034766	negative regulation of ion transmembrane transport	2.177671e-3
GO:0060572	morphogenesis of an epithelial bud	2.207760e-3
GO:0045626	negative regulation of T-helper 1 cell differentiation	2.224037e-3
GO:0001777	T cell homeostatic proliferation	2.224037e-3
GO:0016574	histone ubiquitination	2.227449e-3
GO:0003170	heart valve development	2.336696e-3
GO:0035855	megakaryocyte development	2.340162e-3
GO:0051131	chaperone-mediated protein complex assembly	2.355716e-3
GO:0009048	dosage compensation, by inactivation of X chromosome	2.355716e-3
GO:0007049	cell cycle	2.383045e-3
GO:0045862	positive regulation of proteolysis	2.429904e-3
GO:0045885	positive regulation of survival gene product expression	2.439049e-3
GO:0060068	vagina development	2.551284e-3
GO:0043030	regulation of macrophage activation	2.554434e-3
GO:0035050	embryonic heart tube development	2.575612e-3
GO:0060603	mammary gland duct morphogenesis	2.585185e-3
GO:0008635	activation of caspase activity by cytochrome c	2.619553e-3
GO:0006396	RNA processing	2.638083e-3
GO:0072193	ureter smooth muscle cell differentiation	2.647490e-3
GO:0010458	exit from mitosis	2.647490e-3
GO:0010467	gene expression	2.688728e-3
GO:0034445	negative regulation of plasma lipoprotein particle oxidation	2.702314e-3
GO:0032912	negative regulation of transforming growth factor beta2 production	2.716913e-3
GO:0045665	negative regulation of neuron differentiation	2.762057e-3
GO:0002042	cell migration involved in sprouting angiogenesis	2.840482e-3
GO:0010826	negative regulation of centrosome duplication	2.896099e-3
GO:0035750	protein localization to myelin sheath abaxonal region	2.896099e-3
GO:0000115	regulation of transcription involved in S phase of mitotic cell cycle	2.896099e-3
GO:0042133	neurotransmitter metabolic process	2.922834e-3
GO:0051182	coenzyme transport	2.934129e-3
GO:0006188	IMP biosynthetic process	2.934129e-3
GO:0030330	DNA damage response, signal transduction by p53 class mediator	2.996606e-3
GO:0055026	negative regulation of cardiac muscle tissue development	3.001689e-3
GO:0046668	regulation of retinal cell programmed cell death	3.004324e-3
GO:0060292	long term synaptic depression	3.076280e-3
GO:0090068	positive regulation of cell cycle process	3.132433e-3
GO:0060420	regulation of heart growth	3.219695e-3
GO:0002076	osteoblast development	3.308670e-3
GO:0021986	habenula development	3.337657e-3
GO:0006680	glucosylceramide catabolic process	3.337657e-3
GO:0055024	regulation of cardiac muscle tissue development	3.350311e-3
GO:0006448	regulation of translational elongation	3.356015e-3
GO:0031396	regulation of protein ubiquitination	3.370264e-3
GO:0008033	tRNA processing	3.401935e-3
GO:0060948	cardiac vascular smooth muscle cell development	3.449364e-3
GO:0006265	DNA topological change	3.565175e-3
GO:0080135	regulation of cellular response to stress	3.601351e-3
GO:0072164	mesonephric tubule development	3.605840e-3
GO:0048703	embryonic viscerocranium morphogenesis	3.622588e-3
GO:0034442	regulation of lipoprotein oxidation	3.687810e-3
GO:0035058	nonmotile primary cilium assembly	3.743712e-3
GO:0045599	negative regulation of fat cell differentiation	3.754984e-3
GO:0035404	histone-serine phosphorylation	3.761271e-3
GO:0007043	cell-cell junction assembly	3.789074e-3
GO:0006576	cellular biogenic amine metabolic process	3.907054e-3
GO:0071877	regulation of adrenergic receptor signaling pathway	3.946277e-3
GO:0001824	blastocyst development	4.027576e-3
GO:0008612	peptidyl-lysine modification to hypusine	4.028909e-3
GO:0060043	regulation of cardiac muscle cell proliferation	4.032199e-3
GO:0001505	regulation of neurotransmitter levels	4.045974e-3
GO:0003283	atrial septum development	4.055391e-3
GO:0003349	epicardium-derived cardiac endothelial cell differentiation	4.059217e-3
GO:0046532	regulation of photoreceptor cell differentiation	4.062768e-3
GO:0032446	protein modification by small protein conjugation	4.112849e-3
GO:0072070	loop of Henle development	4.116490e-3
GO:2000822	regulation of behavioral fear response	4.146415e-3
GO:0072171	mesonephric tubule morphogenesis	4.146415e-3
GO:0006809	nitric oxide biosynthetic process	4.146415e-3
GO:0071294	cellular response to zinc ion	4.203301e-3
GO:0015780	nucleotide-sugar transport	4.203301e-3
GO:0071107	response to parathyroid hormone stimulus	4.403104e-3
GO:0019368	fatty acid elongation, unsaturated fatty acid	4.403104e-3
GO:0043968	histone H2A acetylation	4.403104e-3
GO:0060821	inactivation of X chromosome by DNA methylation	4.476717e-3
GO:0060064	Spemann organizer formation at the anterior end of the primitive streak	4.476717e-3
GO:0060267	positive regulation of respiratory burst	4.600999e-3
GO:0060058	positive regulation of apoptosis involved in mammary gland involution	4.684236e-3
GO:0032469	endoplasmic reticulum calcium ion homeostasis	4.684287e-3
GO:0022028	tangential migration from the subventricular zone to the olfactory bulb	4.684287e-3
GO:0009953	dorsal/ventral pattern formation	4.695480e-3
GO:0007521	muscle cell fate determination	4.765693e-3
GO:0000278	mitotic cell cycle	4.787178e-3
GO:0003139	secondary heart field specification	4.844679e-3
GO:0001886	endothelial cell morphogenesis	4.931022e-3
GO:0006868	glutamine transport	4.934745e-3
GO:0035633	maintenance of blood-brain barrier	5.073150e-3
GO:0090342	regulation of cell aging	5.094488e-3
GO:0070995	NADPH oxidation	5.196819e-3
GO:0072075	metanephric mesenchyme development	5.205579e-3
GO:0046015	regulation of transcription by glucose	5.206241e-3
GO:0000432	positive regulation of transcription from RNA polymerase II promoter by glucose	5.399438e-3
GO:0046839	phospholipid dephosphorylation	5.561619e-3
GO:0032026	response to magnesium ion	5.595595e-3
GO:0033239	negative regulation of cellular amine metabolic process	5.771507e-3
GO:0006270	DNA-dependent DNA replication initiation	5.771507e-3
GO:0034653	retinoic acid catabolic process	5.824503e-3
GO:0090161	Golgi ribbon formation	5.824503e-3
GO:0061050	regulation of cell growth involved in cardiac muscle cell development	5.824503e-3
GO:0043558	regulation of translational initiation in response to stress	5.824503e-3
GO:0009211	pyrimidine deoxyribonucleoside triphosphate metabolic process	5.824503e-3
GO:0032509	endosome transport via multivesicular body sorting pathway	5.824503e-3
GO:0033683	nucleotide-excision repair, DNA incision	5.824503e-3
GO:0031400	negative regulation of protein modification process	5.957034e-3
GO:0070407	oxidation-dependent protein catabolic process	6.059758e-3
GO:0043000	Golgi to plasma membrane CFTR protein transport	6.059758e-3
GO:0009794	regulation of mitotic cell cycle, embryonic	6.059758e-3
GO:0007062	sister chromatid cohesion	6.158088e-3
GO:0090197	positive regulation of chemokine secretion	6.199705e-3
GO:0051891	positive regulation of cardioblast differentiation	6.254484e-3
GO:0021766	hippocampus development	6.283007e-3
GO:2001013	epithelial cell proliferation involve in renal tubule morphogenesis	6.320895e-3
GO:0070509	calcium ion import	6.320895e-3
GO:0072160	nephron tubule epithelial cell differentiation	6.320895e-3
GO:0060261	positive regulation of transcription initiation from RNA polymerase II promoter	6.382249e-3
GO:0030264	nuclear fragmentation involved in apoptotic nuclear change	6.396799e-3
GO:0021526	medial motor column neuron differentiation	6.396799e-3
GO:0033523	histone H2B ubiquitination	6.486149e-3
GO:0071340	skeletal muscle nicotinic acetylcholine receptor clustering	6.488054e-3
GO:0090281	negative regulation of calcium ion import	6.488054e-3
GO:0070885	negative regulation of calcineurin-NFAT signaling pathway	6.488054e-3
GO:0071584	negative regulation of zinc ion import	6.488054e-3
GO:0034134	toll-like receptor 2 signaling pathway	6.488054e-3
GO:0051791	medium-chain fatty acid metabolic process	6.488054e-3
GO:0044314	protein K27-linked ubiquitination	6.488054e-3
GO:0048697	positive regulation of collateral sprouting in absence of injury	6.488054e-3
GO:0061056	sclerotome development	6.559696e-3
GO:0042402	cellular biogenic amine catabolic process	6.779541e-3
GO:0019276	UDP-N-acetylgalactosamine metabolic process	6.883507e-3
GO:0044240	multicellular organismal lipid catabolic process	6.947744e-3
GO:0019695	choline metabolic process	6.947744e-3
GO:0060523	prostate epithelial cord elongation	7.040700e-3
GO:0033137	negative regulation of peptidyl-serine phosphorylation	7.187910e-3
GO:0090403	oxidative stress-induced premature senescence	7.332968e-3
GO:0035907	dorsal aorta development	7.332968e-3
GO:0034770	histone H4-K20 methylation	7.332968e-3
GO:0048563	post-embryonic organ morphogenesis	7.342975e-3
GO:0070647	protein modification by small protein conjugation or removal	7.361366e-3
GO:0007008	outer mitochondrial membrane organization	7.404511e-3
GO:0003300	cardiac muscle hypertrophy	7.404511e-3
GO:0043506	regulation of JUN kinase activity	7.610361e-3
GO:0071542	dopaminergic neuron differentiation	7.711676e-3
GO:0035308	negative regulation of protein dephosphorylation	7.711676e-3
GO:0006730	one-carbon metabolic process	7.724122e-3
GO:0071108	protein K48-linked deubiquitination	7.749105e-3
GO:0000189	MAPK import into nucleus	7.930764e-3
GO:0046514	ceramide catabolic process	7.997392e-3
GO:0045936	negative regulation of phosphate metabolic process	8.041821e-3
GO:0060562	epithelial tube morphogenesis	8.160225e-3
GO:0060218	hemopoietic stem cell differentiation	8.171611e-3
GO:0031398	positive regulation of protein ubiquitination	8.247970e-3
GO:2000761	positive regulation of N-terminal peptidyl-lysine acetylation	8.386903e-3
GO:0035910	ascending aorta morphogenesis	8.386903e-3
GO:0050748	negative regulation of lipoprotein metabolic process	8.386903e-3
GO:0000188	inactivation of MAPK activity	8.555026e-3
GO:0050891	multicellular organismal water homeostasis	8.589874e-3
GO:0007368	determination of left/right symmetry	8.689504e-3
GO:0007616	long-term memory	8.819543e-3
GO:0010921	regulation of phosphatase activity	8.878328e-3
GO:0061013	regulation of mRNA catabolic process	8.922978e-3
GO:0060061	Spemann organizer formation	8.956073e-3
GO:0035360	positive regulation of peroxisome proliferator activated receptor signaling pathway	8.956073e-3
GO:0070585	protein localization in mitochondrion	9.048414e-3
GO:0071236	cellular response to antibiotic	9.055836e-3
GO:0019048	virus-host interaction	9.071208e-3
GO:0030299	intestinal cholesterol absorption	9.106056e-3
GO:0010694	positive regulation of alkaline phosphatase activity	9.199183e-3
GO:0043500	muscle adaptation	9.287714e-3
GO:0001844	protein insertion into mitochondrial membrane involved in induction of apoptosis	9.391054e-3
GO:0051597	response to methylmercury	9.605593e-3
GO:0072074	kidney mesenchyme development	9.605593e-3
GO:0021510	spinal cord development	9.626308e-3
GO:0072655	establishment of protein localization in mitochondrion	9.634049e-3
GO:0071482	cellular response to light stimulus	9.634049e-3
GO:0042743	hydrogen peroxide metabolic process	9.888909e-3
GO:0010332	response to gamma radiation	1.013864e-2
GO:0045040	protein import into mitochondrial outer membrane	1.027469e-2
GO:0031987	locomotion involved in locomotory behavior	1.027469e-2
GO:0006325	chromatin organization	1.034368e-2
GO:0033554	cellular response to stress	1.037135e-2
GO:0055098	response to low-density lipoprotein particle stimulus	1.051729e-2
GO:0019377	glycolipid catabolic process	1.051729e-2
GO:0001825	blastocyst formation	1.059118e-2
GO:0071498	cellular response to fluid shear stress	1.074087e-2
GO:0035909	aorta morphogenesis	1.103710e-2
GO:0003309	type B pancreatic cell differentiation	1.122831e-2
GO:0046902	regulation of mitochondrial membrane permeability	1.124198e-2
GO:0071277	cellular response to calcium ion	1.134222e-2
GO:0034405	response to fluid shear stress	1.137957e-2
GO:0006801	superoxide metabolic process	1.137957e-2
GO:0009084	glutamine family amino acid biosynthetic process	1.152653e-2
GO:0090196	regulation of chemokine secretion	1.153431e-2
GO:0010944	negative regulation of transcription by competitive promoter binding	1.154429e-2
GO:2000725	regulation of cardiac muscle cell differentiation	1.167387e-2
GO:0071599	otic vesicle development	1.167387e-2
GO:0060399	positive regulation of growth hormone receptor signaling pathway	1.167856e-2
GO:0009443	pyridoxal 5'-phosphate salvage	1.175228e-2
GO:0032439	endosome localization	1.175228e-2
GO:0003026	regulation of systemic arterial blood pressure by aortic arch baroreceptor feedback	1.175228e-2
GO:0035690	cellular response to drug	1.179058e-2
GO:0006479	protein methylation	1.181404e-2
GO:0071585	detoxification of cadmium ion	1.190034e-2
GO:0002355	detection of tumor cell	1.190034e-2
GO:0060763	mammary duct terminal end bud growth	1.211926e-2
GO:0060914	heart formation	1.213021e-2
GO:0009886	post-embryonic morphogenesis	1.216268e-2
GO:0021527	spinal cord association neuron differentiation	1.235483e-2
GO:0042363	fat-soluble vitamin catabolic process	1.246417e-2
GO:0032055	negative regulation of translation in response to stress	1.246417e-2
GO:0010641	positive regulation of platelet-derived growth factor receptor signaling pathway	1.246417e-2
GO:0009799	specification of symmetry	1.246754e-2
GO:0016570	histone modification	1.248976e-2
GO:0009595	detection of biotic stimulus	1.249105e-2
GO:0032252	secretory granule localization	1.275984e-2
GO:0031124	mRNA 3'-end processing	1.294903e-2
GO:0032516	positive regulation of phosphoprotein phosphatase activity	1.317460e-2
GO:0090136	epithelial cell-cell adhesion	1.322714e-2
GO:0050853	B cell receptor signaling pathway	1.323320e-2
GO:0007006	mitochondrial membrane organization	1.330522e-2
GO:0060485	mesenchyme development	1.343728e-2
GO:0007493	endodermal cell fate determination	1.345302e-2
GO:0010614	negative regulation of cardiac muscle hypertrophy	1.345302e-2
GO:0006699	bile acid biosynthetic process	1.345302e-2
GO:0046496	nicotinamide nucleotide metabolic process	1.348110e-2
GO:0031058	positive regulation of histone modification	1.355703e-2
GO:0034372	very-low-density lipoprotein particle remodeling	1.358258e-2
GO:0031571	mitotic cell cycle G1/S transition DNA damage checkpoint	1.382342e-2
GO:0060992	response to fungicide	1.384510e-2
GO:0045216	cell-cell junction organization	1.386270e-2
GO:0046826	negative regulation of protein export from nucleus	1.414483e-2
GO:0033299	secretion of lysosomal enzymes	1.422899e-2
GO:0006542	glutamine biosynthetic process	1.422899e-2
GO:0045824	negative regulation of innate immune response	1.472699e-2
GO:0001829	trophectodermal cell differentiation	1.502593e-2