Novel motif:134

name:	motif134_ATAAGAGAGGC

Association to promoter expression in human samples<b>Summary:</b>Significance of the correlation with CAGE expression, human <br><b>Analyst:</b> Michiel de Hoon<br><br>link to source dataset <br>data

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Association to promoter expression in mouse samples <b>Summary:</b>Significance of the correlation with CAGE expression, mouse <br><b>Analyst:</b> Michiel de Hoon<br><br>link to source dataset <br>data

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GREAT analysis results for human <b>Summary:</b>Genomic Enrichment of Annotations Tool (GREAT, Nat Biotechnol. 2010 May;28(5):495-501) is used to identify, both in human and in mouse, the gene ontology terms of biological processes enriched given the predicted TFBSs, and evaluated the overlap in the top-500 gene ontology terms between human and mouse. For each novel motif, the P value for the overlap was then evaluated by calculating its relative rank with respect to this background distribution.<br>Analyst: Michiel de Hoon<br><br>link to source dataset <br>data

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GO ID	GO Term	p-value
GO:0061032	visceral serous pericardium development	4.569230e-14
GO:0072302	negative regulation of metanephric glomerular mesangial cell proliferation	4.569230e-14
GO:0032836	glomerular basement membrane development	2.466644e-11
GO:0072166	posterior mesonephric tubule development	2.078936e-10
GO:0050896	response to stimulus	2.832386e-10
GO:0060923	cardiac muscle cell fate commitment	3.284138e-10
GO:0060420	regulation of heart growth	7.433962e-10
GO:2001076	positive regulation of metanephric ureteric bud development	1.228454e-9
GO:0007356	thorax and anterior abdomen determination	1.228454e-9
GO:0043408	regulation of MAPKKK cascade	1.623219e-9
GO:0006935	chemotaxis	1.768299e-9
GO:0072125	negative regulation of glomerular mesangial cell proliferation	2.502577e-9
GO:0035802	adrenal cortex formation	2.626000e-9
GO:0051409	response to nitrosative stress	9.781797e-9
GO:0065007	biological regulation	1.113986e-8
GO:0006955	immune response	1.176127e-8
GO:0032387	negative regulation of intracellular transport	1.191860e-8
GO:0050789	regulation of biological process	2.046790e-8
GO:0006952	defense response	2.123034e-8
GO:0051915	induction of synaptic plasticity by chemical substance	3.718047e-8
GO:0009888	tissue development	4.276643e-8
GO:0010627	regulation of intracellular protein kinase cascade	4.579986e-8
GO:0060539	diaphragm development	6.898473e-8
GO:0002376	immune system process	6.967824e-8
GO:0042742	defense response to bacterium	7.281561e-8
GO:0006782	protoporphyrinogen IX biosynthetic process	7.421815e-8
GO:0035850	epithelial cell differentiation involved in kidney development	7.742545e-8
GO:0045087	innate immune response	8.332216e-8
GO:0072112	glomerular visceral epithelial cell differentiation	1.010087e-7
GO:0007095	mitotic cell cycle G2/M transition DNA damage checkpoint	1.061604e-7
GO:0071780	mitotic cell cycle G2/M transition checkpoint	1.105038e-7
GO:0006950	response to stress	1.108806e-7
GO:0007492	endoderm development	1.311275e-7
GO:0007354	zygotic determination of anterior/posterior axis, embryo	1.326687e-7
GO:0000902	cell morphogenesis	1.409216e-7
GO:0002684	positive regulation of immune system process	1.571641e-7
GO:0002455	humoral immune response mediated by circulating immunoglobulin	1.935517e-7
GO:0007389	pattern specification process	2.032786e-7
GO:0048676	axon extension involved in development	2.368435e-7
GO:0045060	negative thymic T cell selection	2.797869e-7
GO:0006958	complement activation, classical pathway	2.986212e-7
GO:0042663	regulation of endodermal cell fate specification	3.392786e-7
GO:0042738	exogenous drug catabolic process	3.419138e-7
GO:0035234	germ cell programmed cell death	4.374023e-7
GO:0033364	mast cell secretory granule organization	5.061958e-7
GO:0043409	negative regulation of MAPKKK cascade	5.198548e-7
GO:0060421	positive regulation of heart growth	5.809431e-7
GO:0043383	negative T cell selection	5.844697e-7
GO:0043065	positive regulation of apoptosis	5.975679e-7
GO:0032989	cellular component morphogenesis	6.146914e-7
GO:0000904	cell morphogenesis involved in differentiation	6.173644e-7
GO:0048583	regulation of response to stimulus	8.011173e-7
GO:0009605	response to external stimulus	8.193269e-7
GO:0040011	locomotion	8.344219e-7
GO:0006670	sphingosine metabolic process	9.260981e-7
GO:0048812	neuron projection morphogenesis	1.070541e-6
GO:0002682	regulation of immune system process	1.083907e-6
GO:0051716	cellular response to stimulus	1.114466e-6
GO:0051223	regulation of protein transport	1.152700e-6
GO:0009966	regulation of signal transduction	1.495034e-6
GO:0048858	cell projection morphogenesis	1.548016e-6
GO:0032990	cell part morphogenesis	1.646713e-6
GO:0045869	negative regulation of retroviral genome replication	1.697891e-6
GO:0007409	axonogenesis	1.736050e-6
GO:0043068	positive regulation of programmed cell death	1.776954e-6
GO:0002763	positive regulation of myeloid leukocyte differentiation	1.869496e-6
GO:0050794	regulation of cellular process	1.879249e-6
GO:0072301	regulation of metanephric glomerular mesangial cell proliferation	1.887220e-6
GO:0031120	snRNA pseudouridine synthesis	2.251918e-6
GO:0048584	positive regulation of response to stimulus	2.309558e-6
GO:0008588	release of cytoplasmic sequestered NF-kappaB	2.319836e-6
GO:0048667	cell morphogenesis involved in neuron differentiation	2.399761e-6
GO:2000195	negative regulation of female gonad development	2.669894e-6
GO:0047497	mitochondrion transport along microtubule	2.692973e-6
GO:0002883	regulation of hypersensitivity	2.816660e-6
GO:0031295	T cell costimulation	3.160590e-6
GO:0010942	positive regulation of cell death	3.167546e-6
GO:2000194	regulation of female gonad development	3.215388e-6
GO:0042737	drug catabolic process	3.215388e-6
GO:0019724	B cell mediated immunity	3.285679e-6
GO:0032501	multicellular organismal process	3.446502e-6
GO:0023051	regulation of signaling	4.088136e-6
GO:0045606	positive regulation of epidermal cell differentiation	4.197381e-6
GO:0051534	negative regulation of NFAT protein import into nucleus	4.542641e-6
GO:0014012	peripheral nervous system axon regeneration	4.702217e-6
GO:0046823	negative regulation of nucleocytoplasmic transport	4.717613e-6
GO:0030854	positive regulation of granulocyte differentiation	4.766992e-6
GO:2000119	negative regulation of sodium-dependent phosphate transport	4.772837e-6
GO:0023052	signaling	4.794461e-6
GO:0034374	low-density lipoprotein particle remodeling	4.799898e-6
GO:0071371	cellular response to gonadotropin stimulus	5.013808e-6
GO:0002449	lymphocyte mediated immunity	5.018804e-6
GO:0009953	dorsal/ventral pattern formation	5.226713e-6
GO:0002460	adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains	5.255670e-6
GO:0007411	axon guidance	5.496290e-6
GO:0000188	inactivation of MAPK activity	5.537044e-6
GO:0006643	membrane lipid metabolic process	5.681128e-6
GO:0060538	skeletal muscle organ development	5.779835e-6
GO:0016064	immunoglobulin mediated immune response	5.887327e-6
GO:0046519	sphingoid metabolic process	5.971640e-6
GO:0045356	positive regulation of interferon-alpha biosynthetic process	6.092579e-6
GO:0032880	regulation of protein localization	6.360507e-6
GO:0072284	metanephric S-shaped body morphogenesis	6.556138e-6
GO:0034346	positive regulation of type III interferon production	6.904136e-6
GO:0021623	oculomotor nerve formation	7.089063e-6
GO:0003409	optic cup structural organization	7.089063e-6
GO:0003404	optic vesicle morphogenesis	7.089063e-6
GO:0045061	thymic T cell selection	7.217377e-6
GO:0017085	response to insecticide	7.217377e-6
GO:0002443	leukocyte mediated immunity	7.890702e-6
GO:0048522	positive regulation of cellular process	8.136169e-6
GO:0002250	adaptive immune response	8.194698e-6
GO:0051249	regulation of lymphocyte activation	8.374781e-6
GO:0050863	regulation of T cell activation	8.933471e-6
GO:0007416	synapse assembly	9.121038e-6
GO:0010623	developmental programmed cell death	9.136274e-6
GO:0070201	regulation of establishment of protein localization	9.558261e-6
GO:0048638	regulation of developmental growth	9.639655e-6
GO:0006956	complement activation	9.876805e-6
GO:0045666	positive regulation of neuron differentiation	1.008002e-5
GO:0042221	response to chemical stimulus	1.015988e-5
GO:0048588	developmental cell growth	1.107959e-5
GO:0007166	cell surface receptor linked signaling pathway	1.229182e-5
GO:0060341	regulation of cellular localization	1.287643e-5
GO:0033523	histone H2B ubiquitination	1.295535e-5
GO:0032273	positive regulation of protein polymerization	1.345491e-5
GO:0045636	positive regulation of melanocyte differentiation	1.385865e-5
GO:0050776	regulation of immune response	1.519496e-5
GO:0007165	signal transduction	1.576593e-5
GO:0048518	positive regulation of biological process	1.674641e-5
GO:0002761	regulation of myeloid leukocyte differentiation	1.738048e-5
GO:0002839	positive regulation of immune response to tumor cell	1.771764e-5
GO:0090317	negative regulation of intracellular protein transport	1.894629e-5
GO:0090343	positive regulation of cell aging	2.005542e-5
GO:0007154	cell communication	2.005807e-5
GO:0070172	positive regulation of tooth mineralization	2.030603e-5
GO:0032870	cellular response to hormone stimulus	2.049080e-5
GO:0050808	synapse organization	2.125194e-5
GO:0006690	icosanoid metabolic process	2.175738e-5
GO:0032835	glomerulus development	2.188901e-5
GO:0051135	positive regulation of NK T cell activation	2.272098e-5
GO:0042308	negative regulation of protein import into nucleus	2.273403e-5
GO:0070668	positive regulation of mast cell proliferation	2.382098e-5
GO:0071281	cellular response to iron ion	2.397298e-5
GO:0051251	positive regulation of lymphocyte activation	2.436526e-5
GO:0002252	immune effector process	2.490624e-5
GO:0022400	regulation of rhodopsin mediated signaling pathway	2.495544e-5
GO:0016058	maintenance of membrane potential in photoreceptor cell by rhodopsin mediated signaling	2.495544e-5
GO:0003002	regionalization	2.683337e-5
GO:0021783	preganglionic parasympathetic nervous system development	2.890129e-5
GO:0046501	protoporphyrinogen IX metabolic process	2.981692e-5
GO:0030030	cell projection organization	3.167482e-5
GO:0060911	cardiac cell fate commitment	3.207156e-5
GO:2000648	positive regulation of stem cell proliferation	3.258168e-5
GO:0051057	positive regulation of small GTPase mediated signal transduction	3.418659e-5
GO:0072164	mesonephric tubule development	3.699718e-5
GO:0033559	unsaturated fatty acid metabolic process	3.795668e-5
GO:0045634	regulation of melanocyte differentiation	3.797682e-5
GO:0034394	protein localization at cell surface	3.801419e-5
GO:0050870	positive regulation of T cell activation	3.956117e-5
GO:0033762	response to glucagon stimulus	3.986331e-5
GO:0001706	endoderm formation	3.992498e-5
GO:0032386	regulation of intracellular transport	4.020210e-5
GO:2001033	negative regulation of double-strand break repair via nonhomologous end joining	4.160411e-5
GO:2001038	regulation of cellular response to drug	4.160411e-5
GO:2000685	positive regulation of cellular response to X-ray	4.160411e-5
GO:0031052	chromosome breakage	4.160411e-5
GO:0003131	mesodermal-endodermal cell signaling	4.160411e-5
GO:0035978	histone H2A-S139 phosphorylation	4.160411e-5
GO:0051056	regulation of small GTPase mediated signal transduction	4.209032e-5
GO:0031334	positive regulation of protein complex assembly	4.502245e-5
GO:0002864	regulation of acute inflammatory response to antigenic stimulus	4.510428e-5
GO:0046620	regulation of organ growth	4.582345e-5
GO:0050778	positive regulation of immune response	4.587921e-5
GO:0048675	axon extension	4.607072e-5
GO:0031098	stress-activated protein kinase signaling cascade	4.830286e-5
GO:0070665	positive regulation of leukocyte proliferation	4.934459e-5
GO:0021559	trigeminal nerve development	5.136174e-5
GO:0061029	eyelid development in camera-type eye	5.369613e-5
GO:0051654	establishment of mitochondrion localization	5.512973e-5
GO:0050867	positive regulation of cell activation	5.636323e-5
GO:0046456	icosanoid biosynthetic process	5.930514e-5
GO:0002885	positive regulation of hypersensitivity	6.055862e-5
GO:2001021	negative regulation of response to DNA damage stimulus	6.086095e-5
GO:0048486	parasympathetic nervous system development	6.140268e-5
GO:0006959	humoral immune response	6.147773e-5
GO:0045637	regulation of myeloid cell differentiation	6.260570e-5
GO:0045072	regulation of interferon-gamma biosynthetic process	6.264087e-5
GO:0045425	positive regulation of granulocyte macrophage colony-stimulating factor biosynthetic process	6.615983e-5
GO:0032728	positive regulation of interferon-beta production	6.739969e-5
GO:0010741	negative regulation of intracellular protein kinase cascade	6.911282e-5
GO:0042306	regulation of protein import into nucleus	6.966031e-5
GO:0009435	NAD biosynthetic process	6.966760e-5
GO:0031175	neuron projection development	7.058268e-5
GO:0021506	anterior neuropore closure	7.101753e-5
GO:0001822	kidney development	7.348852e-5
GO:0072124	regulation of glomerular mesangial cell proliferation	7.453758e-5
GO:0002756	MyD88-independent toll-like receptor signaling pathway	7.603984e-5
GO:0009306	protein secretion	7.854960e-5
GO:0021557	oculomotor nerve development	7.877340e-5
GO:0045423	regulation of granulocyte macrophage colony-stimulating factor biosynthetic process	7.904094e-5
GO:0042992	negative regulation of transcription factor import into nucleus	8.292906e-5
GO:0001970	positive regulation of activation of membrane attack complex	8.296227e-5
GO:0010944	negative regulation of transcription by competitive promoter binding	8.411826e-5
GO:0080111	DNA demethylation	8.443653e-5
GO:0051403	stress-activated MAPK cascade	8.493209e-5
GO:0032735	positive regulation of interleukin-12 production	8.573152e-5
GO:0045639	positive regulation of myeloid cell differentiation	8.674750e-5
GO:0030154	cell differentiation	8.845183e-5
GO:0001755	neural crest cell migration	9.113739e-5
GO:0046579	positive regulation of Ras protein signal transduction	9.669798e-5
GO:0033363	secretory granule organization	9.852044e-5
GO:0002699	positive regulation of immune effector process	9.939908e-5
GO:0045058	T cell selection	9.959470e-5
GO:0071360	cellular response to exogenous dsRNA	1.085109e-4
GO:0006636	unsaturated fatty acid biosynthetic process	1.089112e-4
GO:0010621	negative regulation of transcription by transcription factor localization	1.098178e-4
GO:0045660	positive regulation of neutrophil differentiation	1.098178e-4
GO:0019442	tryptophan catabolic process to acetyl-CoA	1.135336e-4
GO:0010592	positive regulation of lamellipodium assembly	1.135336e-4
GO:0046822	regulation of nucleocytoplasmic transport	1.140287e-4
GO:0070887	cellular response to chemical stimulus	1.146611e-4
GO:0072075	metanephric mesenchyme development	1.158937e-4
GO:0034589	hydroxyproline transport	1.198582e-4
GO:0015826	threonine transport	1.198582e-4
GO:0045022	early endosome to late endosome transport	1.208190e-4
GO:0071495	cellular response to endogenous stimulus	1.222492e-4
GO:0060485	mesenchyme development	1.243380e-4
GO:0060541	respiratory system development	1.253573e-4
GO:0042574	retinal metabolic process	1.272476e-4
GO:0031507	heterochromatin formation	1.281469e-4
GO:0002860	positive regulation of natural killer cell mediated cytotoxicity directed against tumor cell target	1.305243e-4
GO:0045357	regulation of interferon-beta biosynthetic process	1.312006e-4
GO:0048869	cellular developmental process	1.349053e-4
GO:0060174	limb bud formation	1.358073e-4
GO:0034241	positive regulation of macrophage fusion	1.383427e-4
GO:0048468	cell development	1.388418e-4
GO:0035556	intracellular signal transduction	1.442266e-4
GO:0048087	positive regulation of developmental pigmentation	1.453134e-4
GO:0045738	negative regulation of DNA repair	1.502323e-4
GO:0002253	activation of immune response	1.517341e-4
GO:0032851	positive regulation of Rab GTPase activity	1.517884e-4
GO:0008283	cell proliferation	1.520001e-4
GO:0042520	positive regulation of tyrosine phosphorylation of Stat4 protein	1.550058e-4
GO:0042990	regulation of transcription factor import into nucleus	1.552613e-4
GO:0019359	nicotinamide nucleotide biosynthetic process	1.557082e-4
GO:0034138	toll-like receptor 3 signaling pathway	1.572234e-4
GO:0042908	xenobiotic transport	1.599143e-4
GO:0035590	purinergic nucleotide receptor signaling pathway	1.609383e-4
GO:0033025	regulation of mast cell apoptosis	1.610457e-4
GO:0051606	detection of stimulus	1.626551e-4
GO:0033157	regulation of intracellular protein transport	1.650641e-4
GO:0071377	cellular response to glucagon stimulus	1.658723e-4
GO:0046512	sphingosine biosynthetic process	1.677346e-4
GO:0031529	ruffle organization	1.681221e-4
GO:0030206	chondroitin sulfate biosynthetic process	1.705845e-4
GO:0000185	activation of MAPKKK activity	1.785566e-4
GO:0021535	cell migration in hindbrain	1.843824e-4
GO:0045671	negative regulation of osteoclast differentiation	1.846394e-4
GO:0019538	protein metabolic process	1.851499e-4
GO:0061005	cell differentiation involved in kidney development	1.971637e-4
GO:0035510	DNA dealkylation	2.027702e-4
GO:0045359	positive regulation of interferon-beta biosynthetic process	2.054705e-4
GO:2000107	negative regulation of leukocyte apoptosis	2.054770e-4
GO:0032510	endosome to lysosome transport via multivesicular body sorting pathway	2.079178e-4
GO:0048701	embryonic cranial skeleton morphogenesis	2.096527e-4
GO:0060658	nipple morphogenesis	2.109726e-4
GO:0060021	palate development	2.130451e-4
GO:0007155	cell adhesion	2.208394e-4
GO:0042790	transcription of nuclear large rRNA transcript from RNA polymerase I promoter	2.210018e-4
GO:0035691	macrophage migration inhibitory factor signaling pathway	2.210018e-4
GO:0002696	positive regulation of leukocyte activation	2.213227e-4
GO:0070170	regulation of tooth mineralization	2.227659e-4
GO:0006680	glucosylceramide catabolic process	2.251866e-4
GO:0006784	heme a biosynthetic process	2.275799e-4
GO:0006123	mitochondrial electron transport, cytochrome c to oxygen	2.275799e-4
GO:0035988	chondrocyte proliferation	2.281576e-4
GO:0035458	cellular response to interferon-beta	2.282931e-4
GO:0048519	negative regulation of biological process	2.292147e-4
GO:0016572	histone phosphorylation	2.331930e-4
GO:0071894	histone H2B conserved C-terminal lysine ubiquitination	2.333711e-4
GO:0030217	T cell differentiation	2.346772e-4
GO:0043407	negative regulation of MAP kinase activity	2.411564e-4
GO:0046514	ceramide catabolic process	2.416239e-4
GO:0006665	sphingolipid metabolic process	2.492641e-4
GO:0044255	cellular lipid metabolic process	2.503762e-4
GO:0048523	negative regulation of cellular process	2.505014e-4
GO:0046578	regulation of Ras protein signal transduction	2.507780e-4
GO:0007638	mechanosensory behavior	2.518296e-4
GO:0006112	energy reserve metabolic process	2.633866e-4
GO:0050865	regulation of cell activation	2.728529e-4
GO:0035587	purinergic receptor signaling pathway	2.734624e-4
GO:0007632	visual behavior	2.735591e-4
GO:0001553	luteinization	2.736376e-4
GO:0010536	positive regulation of activation of Janus kinase activity	2.839084e-4
GO:0045354	regulation of interferon-alpha biosynthetic process	2.839084e-4
GO:0045059	positive thymic T cell selection	2.848614e-4
GO:0070375	BMK cascade	2.859581e-4
GO:0071320	cellular response to cAMP	2.861780e-4
GO:0010646	regulation of cell communication	2.874853e-4
GO:0007243	intracellular protein kinase cascade	2.875111e-4
GO:0045954	positive regulation of natural killer cell mediated cytotoxicity	2.916266e-4
GO:0045085	negative regulation of interleukin-2 biosynthetic process	2.916559e-4
GO:0034436	glycoprotein transport	2.929987e-4
GO:0009720	detection of hormone stimulus	2.929987e-4
GO:2000121	regulation of removal of superoxide radicals	2.938956e-4
GO:0050731	positive regulation of peptidyl-tyrosine phosphorylation	3.010647e-4
GO:0061162	establishment of monopolar cell polarity	3.149938e-4
GO:0051224	negative regulation of protein transport	3.154202e-4
GO:0048639	positive regulation of developmental growth	3.155438e-4
GO:0008354	germ cell migration	3.162851e-4
GO:0031223	auditory behavior	3.177025e-4
GO:0046618	drug export	3.284615e-4
GO:0072001	renal system development	3.369237e-4
GO:0050650	chondroitin sulfate proteoglycan biosynthetic process	3.471205e-4
GO:0060649	mammary gland bud elongation	3.512004e-4
GO:0060659	nipple sheath formation	3.512004e-4
GO:0042769	DNA damage response, detection of DNA damage	3.543794e-4
GO:0006023	aminoglycan biosynthetic process	3.582151e-4
GO:0032481	positive regulation of type I interferon production	3.592544e-4
GO:0019363	pyridine nucleotide biosynthetic process	3.613018e-4
GO:0010966	regulation of phosphate transport	3.660519e-4
GO:0007163	establishment or maintenance of cell polarity	3.676403e-4
GO:0033077	T cell differentiation in thymus	3.734343e-4
GO:0010574	regulation of vascular endothelial growth factor production	3.750765e-4
GO:0052033	pathogen-associated molecular pattern dependent induction by symbiont of host innate immunity	3.851800e-4
GO:0010887	negative regulation of cholesterol storage	3.926211e-4
GO:0043619	regulation of transcription from RNA polymerase II promoter in response to oxidative stress	3.982502e-4
GO:0033026	negative regulation of mast cell apoptosis	4.010990e-4
GO:0009967	positive regulation of signal transduction	4.036048e-4
GO:0031508	centromeric heterochromatin formation	4.068626e-4
GO:0090342	regulation of cell aging	4.092435e-4
GO:0030097	hemopoiesis	4.175393e-4
GO:0060464	lung lobe formation	4.217562e-4
GO:0010970	microtubule-based transport	4.219306e-4
GO:0001562	response to protozoan	4.227580e-4
GO:0003289	atrial septum primum morphogenesis	4.290399e-4
GO:0031576	G2/M transition checkpoint	4.416018e-4
GO:0048070	regulation of developmental pigmentation	4.424435e-4
GO:0019674	NAD metabolic process	4.499471e-4
GO:0002446	neutrophil mediated immunity	4.557590e-4
GO:0019370	leukotriene biosynthetic process	4.585190e-4
GO:0007417	central nervous system development	4.588690e-4
GO:2000020	positive regulation of male gonad development	4.644982e-4
GO:0046521	sphingoid catabolic process	4.859274e-4
GO:0002866	positive regulation of acute inflammatory response to antigenic stimulus	4.859274e-4
GO:0002694	regulation of leukocyte activation	4.877127e-4
GO:0030223	neutrophil differentiation	5.079861e-4
GO:0043405	regulation of MAP kinase activity	5.328740e-4
GO:0009202	deoxyribonucleoside triphosphate biosynthetic process	5.344619e-4
GO:0070236	negative regulation of activation-induced cell death of T cells	5.364188e-4
GO:0045090	retroviral genome replication	5.364188e-4
GO:0042118	endothelial cell activation	5.393512e-4
GO:2000343	positive regulation of chemokine (C-X-C motif) ligand 2 production	5.445923e-4
GO:0034123	positive regulation of toll-like receptor signaling pathway	5.488092e-4
GO:0006972	hyperosmotic response	5.488092e-4
GO:0043966	histone H3 acetylation	5.588260e-4
GO:0006024	glycosaminoglycan biosynthetic process	5.592469e-4
GO:0050708	regulation of protein secretion	5.599724e-4
GO:0001667	ameboidal cell migration	5.629013e-4
GO:0030832	regulation of actin filament length	5.642452e-4
GO:0030149	sphingolipid catabolic process	5.918281e-4
GO:0016198	axon choice point recognition	6.018336e-4
GO:0046777	protein autophosphorylation	6.060039e-4
GO:0009597	detection of virus	6.119622e-4
GO:0030041	actin filament polymerization	6.145025e-4
GO:0042981	regulation of apoptosis	6.172098e-4
GO:0051532	regulation of NFAT protein import into nucleus	6.278692e-4
GO:0051046	regulation of secretion	6.297764e-4
GO:0045088	regulation of innate immune response	6.389297e-4
GO:0060004	reflex	6.440557e-4
GO:0010648	negative regulation of cell communication	6.441293e-4
GO:0017148	negative regulation of translation	6.455246e-4
GO:0006672	ceramide metabolic process	6.508254e-4
GO:0046466	membrane lipid catabolic process	6.742391e-4
GO:0046427	positive regulation of JAK-STAT cascade	6.777292e-4
GO:0001704	formation of primary germ layer	6.941856e-4
GO:0044272	sulfur compound biosynthetic process	6.999613e-4
GO:0046622	positive regulation of organ growth	7.052444e-4
GO:0032509	endosome transport via multivesicular body sorting pathway	7.058323e-4
GO:0071895	odontoblast differentiation	7.093150e-4
GO:0055099	response to high density lipoprotein particle stimulus	7.093150e-4
GO:0008542	visual learning	7.126052e-4
GO:0002009	morphogenesis of an epithelium	7.163573e-4
GO:0006790	sulfur compound metabolic process	7.244333e-4
GO:0001655	urogenital system development	7.245943e-4
GO:0035589	G-protein coupled purinergic nucleotide receptor signaling pathway	7.309019e-4
GO:0072355	histone H3-T3 phosphorylation	7.338518e-4
GO:0045658	regulation of neutrophil differentiation	7.391090e-4
GO:0048630	skeletal muscle tissue growth	7.498410e-4
GO:0051085	chaperone mediated protein folding requiring cofactor	7.540176e-4
GO:0030952	establishment or maintenance of cytoskeleton polarity	7.560675e-4
GO:0060907	positive regulation of macrophage cytokine production	7.895550e-4
GO:0002282	microglial cell activation involved in immune response	7.919274e-4
GO:0051489	regulation of filopodium assembly	8.018331e-4
GO:0014031	mesenchymal cell development	8.091779e-4
GO:0006869	lipid transport	8.159812e-4
GO:0050793	regulation of developmental process	8.243274e-4
GO:0002695	negative regulation of leukocyte activation	8.269874e-4
GO:0048333	mesodermal cell differentiation	8.367697e-4
GO:0043067	regulation of programmed cell death	8.373413e-4
GO:0001817	regulation of cytokine production	8.384690e-4
GO:0009987	cellular process	8.448344e-4
GO:0001662	behavioral fear response	8.449638e-4
GO:0032717	negative regulation of interleukin-8 production	8.568284e-4
GO:0071899	negative regulation of estrogen receptor binding	8.773539e-4
GO:0023057	negative regulation of signaling	8.846363e-4
GO:0090402	oncogene-induced senescence	8.868277e-4
GO:0006678	glucosylceramide metabolic process	9.304573e-4
GO:0034698	response to gonadotropin stimulus	9.367713e-4
GO:0007405	neuroblast proliferation	9.464735e-4
GO:0061153	trachea gland development	9.918468e-4
GO:0030838	positive regulation of actin filament polymerization	9.936124e-4
GO:0006691	leukotriene metabolic process	9.947260e-4
GO:0051088	PMA-inducible membrane protein ectodomain proteolysis	9.957889e-4
GO:0048705	skeletal system morphogenesis	1.005475e-3
GO:0001837	epithelial to mesenchymal transition	1.007039e-3
GO:0030182	neuron differentiation	1.028901e-3
GO:0070663	regulation of leukocyte proliferation	1.038662e-3
GO:0060127	prolactin secreting cell differentiation	1.040095e-3
GO:0061325	cell proliferation involved in outflow tract morphogenesis	1.040095e-3
GO:0003253	cardiac neural crest cell migration involved in outflow tract morphogenesis	1.040095e-3
GO:0032648	regulation of interferon-beta production	1.052761e-3
GO:0010935	regulation of macrophage cytokine production	1.052761e-3
GO:0009410	response to xenobiotic stimulus	1.062231e-3
GO:0046425	regulation of JAK-STAT cascade	1.081745e-3
GO:0030705	cytoskeleton-dependent intracellular transport	1.093429e-3
GO:0006720	isoprenoid metabolic process	1.106085e-3
GO:0002209	behavioral defense response	1.111256e-3
GO:0030539	male genitalia development	1.113305e-3
GO:0009615	response to virus	1.141514e-3
GO:0002072	optic cup morphogenesis involved in camera-type eye development	1.167958e-3
GO:0071466	cellular response to xenobiotic stimulus	1.179755e-3
GO:0006805	xenobiotic metabolic process	1.183592e-3
GO:0071526	semaphorin-plexin signaling pathway	1.199112e-3
GO:0043569	negative regulation of insulin-like growth factor receptor signaling pathway	1.231379e-3
GO:0071864	positive regulation of cell proliferation in bone marrow	1.231677e-3
GO:0071866	negative regulation of apoptosis in bone marrow	1.231677e-3
GO:0035330	regulation of hippo signaling cascade	1.231677e-3
GO:0002504	antigen processing and presentation of peptide or polysaccharide antigen via MHC class II	1.234235e-3
GO:0009968	negative regulation of signal transduction	1.234364e-3
GO:0006629	lipid metabolic process	1.237338e-3
GO:0051799	negative regulation of hair follicle development	1.240596e-3
GO:0035588	G-protein coupled purinergic receptor signaling pathway	1.249166e-3
GO:0061351	neural precursor cell proliferation	1.257136e-3
GO:0002224	toll-like receptor signaling pathway	1.281715e-3
GO:0043567	regulation of insulin-like growth factor receptor signaling pathway	1.286702e-3
GO:0002092	positive regulation of receptor internalization	1.305404e-3
GO:0019441	tryptophan catabolic process to kynurenine	1.310600e-3
GO:0055091	phospholipid homeostasis	1.310600e-3
GO:0046496	nicotinamide nucleotide metabolic process	1.326962e-3
GO:0021935	cerebellar granule cell precursor tangential migration	1.326972e-3
GO:0043308	eosinophil degranulation	1.337607e-3
GO:0045226	extracellular polysaccharide biosynthetic process	1.357003e-3
GO:0048666	neuron development	1.362492e-3
GO:0006776	vitamin A metabolic process	1.365553e-3
GO:0001798	positive regulation of type IIa hypersensitivity	1.369317e-3
GO:0090066	regulation of anatomical structure size	1.370602e-3
GO:0050973	detection of mechanical stimulus involved in equilibrioception	1.385358e-3
GO:0035695	mitochondrion degradation by induced vacuole formation	1.385358e-3
GO:0017186	peptidyl-pyroglutamic acid biosynthetic process, using glutaminyl-peptide cyclotransferase	1.395938e-3
GO:0002347	response to tumor cell	1.395938e-3
GO:0048534	hemopoietic or lymphoid organ development	1.402244e-3
GO:2000779	regulation of double-strand break repair	1.412387e-3
GO:0010575	positive regulation vascular endothelial growth factor production	1.414429e-3
GO:0046467	membrane lipid biosynthetic process	1.415605e-3
GO:0003334	keratinocyte development	1.418764e-3
GO:0060056	mammary gland involution	1.422810e-3
GO:0033382	maintenance of granzyme B location in T cell secretory granule	1.430231e-3
GO:0033373	maintenance of protease location in mast cell secretory granule	1.430231e-3
GO:0007612	learning	1.477348e-3
GO:0031116	positive regulation of microtubule polymerization	1.487349e-3
GO:0030204	chondroitin sulfate metabolic process	1.492975e-3
GO:0002702	positive regulation of production of molecular mediator of immune response	1.540933e-3
GO:0007519	skeletal muscle tissue development	1.553182e-3
GO:2000018	regulation of male gonad development	1.589087e-3
GO:0060013	righting reflex	1.596354e-3
GO:0003357	noradrenergic neuron differentiation	1.618326e-3
GO:0022601	menstrual cycle phase	1.656634e-3
GO:0051646	mitochondrion localization	1.675505e-3
GO:2000353	positive regulation of endothelial cell apoptosis	1.681413e-3
GO:0045815	positive regulation of gene expression, epigenetic	1.691405e-3
GO:0046853	inositol or phosphatidylinositol phosphorylation	1.744525e-3
GO:0072334	UDP-galactose transmembrane transport	1.744525e-3
GO:0032780	negative regulation of ATPase activity	1.755800e-3
GO:0007525	somatic muscle development	1.769992e-3
GO:0010941	regulation of cell death	1.788344e-3
GO:0010876	lipid localization	1.798517e-3
GO:0046520	sphingoid biosynthetic process	1.897031e-3
GO:0035105	sterol regulatory element binding protein import into nucleus	1.930031e-3
GO:0000920	cytokinetic cell separation	1.936131e-3
GO:0045089	positive regulation of innate immune response	1.956231e-3
GO:0002830	positive regulation of type 2 immune response	1.962885e-3
GO:0050848	regulation of calcium-mediated signaling	1.972593e-3
GO:0044258	intestinal lipid catabolic process	1.980401e-3
GO:0018350	protein esterification	1.980401e-3
GO:0045927	positive regulation of growth	2.002790e-3
GO:0065009	regulation of molecular function	2.032022e-3
GO:0032946	positive regulation of mononuclear cell proliferation	2.059742e-3
GO:0031349	positive regulation of defense response	2.079065e-3

GREAT analysis results for mouseGenomic Enrichment of Annotations Tool (GREAT, Nat Biotechnol. 2010 May;28(5):495-501) is used to identify, both in human and in mouse, the gene ontology terms of biological processes enriched given the predicted TFBSs, and evaluated the overlap in the top-500 gene ontology terms between human and mouse. For each novel motif, the P value for the overlap was then evaluated by calculating its relative rank with respect to this background distribution.<br>Analyst: Michiel de Hoon <br><br>link to source dataset <br>data

---

GO ID	GO Term	p-value
GO:0016579	protein deubiquitination	3.879762e-23
GO:0070646	protein modification by small protein removal	2.453298e-19
GO:0090303	positive regulation of wound healing	7.239369e-9
GO:0007354	zygotic determination of anterior/posterior axis, embryo	5.537199e-8
GO:0060421	positive regulation of heart growth	6.858635e-8
GO:0003050	regulation of systemic arterial blood pressure by atrial natriuretic peptide	1.059258e-7
GO:0072015	glomerular visceral epithelial cell development	1.220773e-7
GO:0072301	regulation of metanephric glomerular mesangial cell proliferation	1.519573e-7
GO:0006116	NADH oxidation	1.922452e-7
GO:0070071	proton-transporting two-sector ATPase complex assembly	2.182925e-7
GO:0000028	ribosomal small subunit assembly	2.238177e-7
GO:0003008	system process	2.414970e-7
GO:0010594	regulation of endothelial cell migration	2.709551e-7
GO:0042274	ribosomal small subunit biogenesis	3.068011e-7
GO:2000195	negative regulation of female gonad development	3.262662e-7
GO:2001076	positive regulation of metanephric ureteric bud development	4.090135e-7
GO:0007356	thorax and anterior abdomen determination	4.090135e-7
GO:0072302	negative regulation of metanephric glomerular mesangial cell proliferation	4.090135e-7
GO:0044329	canonical Wnt receptor signaling pathway involved in positive regulation of cell-cell adhesion	4.274242e-7
GO:0044330	canonical Wnt receptor signaling pathway involved in positive regulation of wound healing	4.274242e-7
GO:0044328	canonical Wnt receptor signaling pathway involved in positive regulation of endothelial cell migration	4.274242e-7
GO:0072112	glomerular visceral epithelial cell differentiation	5.912265e-7
GO:0090076	relaxation of skeletal muscle	6.857557e-7
GO:0032470	elevation of endoplasmic reticulum calcium ion concentration	6.857557e-7
GO:0070509	calcium ion import	9.226451e-7
GO:0016074	snoRNA metabolic process	9.226451e-7
GO:2000194	regulation of female gonad development	9.268160e-7
GO:0010817	regulation of hormone levels	9.781890e-7
GO:0007613	memory	1.110865e-6
GO:0016486	peptide hormone processing	1.165050e-6
GO:2000242	negative regulation of reproductive process	1.398982e-6
GO:0008595	anterior/posterior axis specification, embryo	2.242017e-6
GO:0070327	thyroid hormone transport	3.501072e-6
GO:0071347	cellular response to interleukin-1	3.533881e-6
GO:0031448	positive regulation of fast-twitch skeletal muscle fiber contraction	3.792070e-6
GO:0006508	proteolysis	3.953866e-6
GO:0042438	melanin biosynthetic process	4.106820e-6
GO:0045785	positive regulation of cell adhesion	4.123360e-6
GO:0072166	posterior mesonephric tubule development	4.729829e-6
GO:0045924	regulation of female receptivity	4.735301e-6
GO:0032800	receptor biosynthetic process	5.959961e-6
GO:0072329	monocarboxylic acid catabolic process	6.096463e-6
GO:2000271	positive regulation of fibroblast apoptosis	6.188493e-6
GO:2000270	negative regulation of fibroblast apoptosis	6.188493e-6
GO:0044345	stromal-epithelial cell signaling involved in prostate gland development	6.188493e-6
GO:2000080	negative regulation of canonical Wnt receptor signaling pathway involved in controlling type B pancreatic cell proliferation	6.188493e-6
GO:0070072	vacuolar proton-transporting V-type ATPase complex assembly	6.844928e-6
GO:0033189	response to vitamin A	7.009144e-6
GO:0006670	sphingosine metabolic process	7.704365e-6
GO:0007621	negative regulation of female receptivity	7.725020e-6
GO:0009914	hormone transport	8.389533e-6
GO:0006582	melanin metabolic process	8.906879e-6
GO:0006412	translation	9.652418e-6
GO:0007253	cytoplasmic sequestering of NF-kappaB	1.045634e-5
GO:2000079	regulation of canonical Wnt receptor signaling pathway involved in controlling type B pancreatic cell proliferation	1.093489e-5
GO:0071380	cellular response to prostaglandin E stimulus	1.093489e-5
GO:0021539	subthalamus development	1.093489e-5
GO:0016078	tRNA catabolic process	1.182886e-5
GO:0001682	tRNA 5'-leader removal	1.182886e-5
GO:0018924	mandelate metabolic process	1.298010e-5
GO:0032471	reduction of endoplasmic reticulum calcium ion concentration	1.338989e-5
GO:0006700	C21-steroid hormone biosynthetic process	1.378087e-5
GO:0035282	segmentation	1.387728e-5
GO:0042255	ribosome assembly	1.390425e-5
GO:0050896	response to stimulus	1.604940e-5
GO:0060849	regulation of transcription involved in lymphatic endothelial cell fate commitment	1.626827e-5
GO:0001936	regulation of endothelial cell proliferation	1.648294e-5
GO:0045046	protein import into peroxisome membrane	1.902684e-5
GO:0060923	cardiac muscle cell fate commitment	1.968514e-5
GO:0060180	female mating behavior	1.968514e-5
GO:0030490	maturation of SSU-rRNA	2.049073e-5
GO:0072125	negative regulation of glomerular mesangial cell proliferation	2.251534e-5
GO:0006927	transformed cell apoptosis	2.251534e-5
GO:0072124	regulation of glomerular mesangial cell proliferation	2.372591e-5
GO:0060839	endothelial cell fate commitment	2.372591e-5
GO:0000578	embryonic axis specification	2.399637e-5
GO:0042938	dipeptide transport	2.430977e-5
GO:0009062	fatty acid catabolic process	2.742592e-5
GO:0030855	epithelial cell differentiation	2.775056e-5
GO:0070309	lens fiber cell morphogenesis	2.848700e-5
GO:0060836	lymphatic endothelial cell differentiation	2.848700e-5
GO:0034612	response to tumor necrosis factor	2.978805e-5
GO:0035802	adrenal cortex formation	3.365080e-5
GO:0022409	positive regulation of cell-cell adhesion	3.710658e-5
GO:0060766	negative regulation of androgen receptor signaling pathway	3.875448e-5
GO:0023052	signaling	5.030501e-5
GO:0051220	cytoplasmic sequestering of protein	5.213499e-5
GO:0072659	protein localization in plasma membrane	5.877123e-5
GO:0072179	nephric duct formation	5.963378e-5
GO:0061004	pattern specification involved in kidney development	5.963378e-5
GO:0006631	fatty acid metabolic process	6.266754e-5
GO:2000020	positive regulation of male gonad development	6.300485e-5
GO:0072284	metanephric S-shaped body morphogenesis	6.308669e-5
GO:0072278	metanephric comma-shaped body morphogenesis	6.308669e-5
GO:0033273	response to vitamin	6.380234e-5
GO:0007154	cell communication	6.389664e-5
GO:0016485	protein processing	6.395696e-5
GO:2000241	regulation of reproductive process	6.821324e-5
GO:0006863	purine base transport	7.191844e-5
GO:0051716	cellular response to stimulus	7.337232e-5
GO:0060675	ureteric bud morphogenesis	7.600431e-5
GO:0001743	optic placode formation	8.458503e-5
GO:0009798	axis specification	8.624018e-5
GO:0044237	cellular metabolic process	8.671854e-5
GO:0046512	sphingosine biosynthetic process	8.893327e-5
GO:0010595	positive regulation of endothelial cell migration	9.137029e-5
GO:0090192	regulation of glomerulus development	9.157143e-5
GO:2000018	regulation of male gonad development	9.290211e-5
GO:0051561	elevation of mitochondrial calcium ion concentration	9.290211e-5
GO:0046622	positive regulation of organ growth	9.583143e-5
GO:0035470	positive regulation of vascular wound healing	9.738628e-5
GO:0032715	negative regulation of interleukin-6 production	9.905832e-5
GO:0042445	hormone metabolic process	1.022870e-4
GO:0001555	oocyte growth	1.031369e-4
GO:0015747	urate transport	1.119834e-4
GO:0033144	negative regulation of steroid hormone receptor signaling pathway	1.177777e-4
GO:0033057	multicellular organismal reproductive behavior	1.199312e-4
GO:0008152	metabolic process	1.244035e-4
GO:0045212	neurotransmitter receptor biosynthetic process	1.288856e-4
GO:0002268	follicular dendritic cell differentiation	1.288856e-4
GO:0045598	regulation of fat cell differentiation	1.300817e-4
GO:0051259	protein oligomerization	1.300887e-4
GO:0019748	secondary metabolic process	1.431951e-4
GO:0071356	cellular response to tumor necrosis factor	1.577297e-4
GO:0001823	mesonephros development	1.597422e-4
GO:0046037	GMP metabolic process	1.624164e-4
GO:0051646	mitochondrion localization	1.687868e-4
GO:0015908	fatty acid transport	1.687868e-4
GO:0050654	chondroitin sulfate proteoglycan metabolic process	1.699187e-4
GO:0071479	cellular response to ionizing radiation	1.735710e-4
GO:0051896	regulation of protein kinase B signaling cascade	1.986630e-4
GO:0008050	female courtship behavior	2.054573e-4
GO:0042891	antibiotic transport	2.077632e-4
GO:0046619	optic placode formation involved in camera-type eye formation	2.081694e-4
GO:0022407	regulation of cell-cell adhesion	2.112260e-4
GO:0051604	protein maturation	2.112260e-4
GO:0009966	regulation of signal transduction	2.201040e-4
GO:0060527	prostate epithelial cord arborization involved in prostate glandular acinus morphogenesis	2.333626e-4
GO:0015851	nucleobase transport	2.362833e-4
GO:0019227	neuronal action potential propagation	2.362833e-4
GO:0090183	regulation of kidney development	2.534307e-4
GO:0016557	peroxisome membrane biogenesis	2.573039e-4
GO:0000105	histidine biosynthetic process	2.573039e-4
GO:0006424	glutamyl-tRNA aminoacylation	2.573039e-4
GO:0032526	response to retinoic acid	2.591905e-4
GO:0072337	modified amino acid transport	2.617753e-4
GO:0001938	positive regulation of endothelial cell proliferation	2.631790e-4
GO:0009948	anterior/posterior axis specification	2.651998e-4
GO:0006734	NADH metabolic process	2.701640e-4
GO:0032780	negative regulation of ATPase activity	2.743414e-4
GO:0071109	superior temporal gyrus development	2.754997e-4
GO:0002024	diet induced thermogenesis	2.859689e-4
GO:0072148	epithelial cell fate commitment	2.862543e-4
GO:0051897	positive regulation of protein kinase B signaling cascade	2.923361e-4
GO:0050482	arachidonic acid secretion	2.992152e-4
GO:0071504	cellular response to heparin	3.015908e-4
GO:0007165	signal transduction	3.059217e-4
GO:0042994	cytoplasmic sequestering of transcription factor	3.089850e-4
GO:0050680	negative regulation of epithelial cell proliferation	3.107394e-4
GO:0060911	cardiac cell fate commitment	3.254573e-4
GO:0044282	small molecule catabolic process	3.263524e-4
GO:0015718	monocarboxylic acid transport	3.273309e-4
GO:0045988	negative regulation of striated muscle contraction	3.318817e-4
GO:0072050	S-shaped body morphogenesis	3.422635e-4
GO:0002726	positive regulation of T cell cytokine production	3.422635e-4
GO:0072049	comma-shaped body morphogenesis	3.422635e-4
GO:0032787	monocarboxylic acid metabolic process	3.437724e-4
GO:0071392	cellular response to estradiol stimulus	3.542325e-4
GO:0035564	regulation of kidney size	3.544234e-4
GO:0019800	peptide cross-linking via chondroitin 4-sulfate glycosaminoglycan	3.630557e-4
GO:0007166	cell surface receptor linked signaling pathway	3.741340e-4
GO:0030327	prenylated protein catabolic process	3.867605e-4
GO:0010596	negative regulation of endothelial cell migration	3.945714e-4
GO:0060850	regulation of transcription involved in cell fate commitment	4.001364e-4
GO:0007214	gamma-aminobutyric acid signaling pathway	4.001364e-4
GO:0071503	response to heparin	4.149672e-4
GO:0065008	regulation of biological quality	4.293631e-4
GO:0090285	negative regulation of protein glycosylation in Golgi	4.307085e-4
GO:0072086	specification of loop of Henle identity	4.415227e-4
GO:0046395	carboxylic acid catabolic process	4.435194e-4
GO:0044238	primary metabolic process	4.618545e-4
GO:0009612	response to mechanical stimulus	4.738799e-4
GO:0051497	negative regulation of stress fiber assembly	4.807454e-4
GO:0045840	positive regulation of mitosis	4.835731e-4
GO:0009409	response to cold	4.838823e-4
GO:0023051	regulation of signaling	4.875391e-4
GO:0001655	urogenital system development	5.046762e-4
GO:0072298	regulation of metanephric glomerulus development	5.050369e-4
GO:0070857	regulation of bile acid biosynthetic process	5.143298e-4
GO:2000117	negative regulation of cysteine-type endopeptidase activity	5.143298e-4
GO:2001052	positive regulation of G1/S transition checkpoint	5.212309e-4
GO:0072574	hepatocyte proliferation	5.212309e-4
GO:0002194	hepatocyte cell migration	5.212309e-4
GO:0033205	cell cycle cytokinesis	5.500413e-4
GO:0042439	ethanolamine-containing compound metabolic process	5.787084e-4
GO:0060296	regulation of cilium beat frequency involved in ciliary motility	5.968967e-4
GO:0045995	regulation of embryonic development	6.063647e-4
GO:0035567	non-canonical Wnt receptor signaling pathway	6.189653e-4
GO:0045069	regulation of viral genome replication	6.361491e-4
GO:0090075	relaxation of muscle	6.439888e-4
GO:0072081	specification of nephron tubule identity	6.512616e-4
GO:0060346	bone trabecula formation	6.665442e-4
GO:0006663	platelet activating factor biosynthetic process	6.740979e-4
GO:0060512	prostate gland morphogenesis	7.031181e-4
GO:0003158	endothelium development	7.096092e-4
GO:0001649	osteoblast differentiation	7.102852e-4
GO:0022603	regulation of anatomical structure morphogenesis	7.106703e-4
GO:0035928	rRNA import into mitochondrion	7.163415e-4
GO:0051241	negative regulation of multicellular organismal process	7.416389e-4
GO:0060688	regulation of morphogenesis of a branching structure	7.487923e-4
GO:0043933	macromolecular complex subunit organization	8.299098e-4
GO:0050793	regulation of developmental process	8.428733e-4
GO:0042440	pigment metabolic process	8.507316e-4
GO:0031929	TOR signaling cascade	8.670257e-4
GO:0006082	organic acid metabolic process	8.677690e-4
GO:0033689	negative regulation of osteoblast proliferation	8.737185e-4
GO:0007619	courtship behavior	8.737185e-4
GO:0048609	multicellular organismal reproductive process	8.793453e-4
GO:0015909	long-chain fatty acid transport	8.865301e-4
GO:0048312	intracellular distribution of mitochondria	8.923606e-4
GO:0032020	ISG15-protein conjugation	9.176452e-4
GO:0046323	glucose import	9.176452e-4
GO:0050877	neurological system process	9.215118e-4
GO:0072074	kidney mesenchyme development	9.238037e-4
GO:0072178	nephric duct morphogenesis	9.477414e-4
GO:2000026	regulation of multicellular organismal development	9.542295e-4
GO:0070858	negative regulation of bile acid biosynthetic process	9.649928e-4
GO:0042446	hormone biosynthetic process	9.841455e-4
GO:0043568	positive regulation of insulin-like growth factor receptor signaling pathway	9.951006e-4
GO:0035850	epithelial cell differentiation involved in kidney development	9.956714e-4
GO:0046851	negative regulation of bone remodeling	1.002827e-3
GO:0030388	fructose 1,6-bisphosphate metabolic process	1.024565e-3
GO:0060740	prostate gland epithelium morphogenesis	1.035887e-3
GO:0031652	positive regulation of heat generation	1.051693e-3
GO:2000027	regulation of organ morphogenesis	1.074106e-3
GO:0045578	negative regulation of B cell differentiation	1.079805e-3
GO:0046148	pigment biosynthetic process	1.117333e-3
GO:0044260	cellular macromolecule metabolic process	1.129909e-3
GO:0045765	regulation of angiogenesis	1.133047e-3
GO:0006704	glucocorticoid biosynthetic process	1.138700e-3
GO:0071305	cellular response to vitamin D	1.146411e-3
GO:0071345	cellular response to cytokine stimulus	1.158597e-3
GO:0071481	cellular response to X-ray	1.167556e-3
GO:0009628	response to abiotic stimulus	1.185216e-3
GO:0045843	negative regulation of striated muscle tissue development	1.189341e-3
GO:0006548	histidine catabolic process	1.196421e-3
GO:0009880	embryonic pattern specification	1.202481e-3
GO:0042221	response to chemical stimulus	1.206443e-3
GO:0002676	regulation of chronic inflammatory response	1.227528e-3
GO:0019395	fatty acid oxidation	1.243575e-3
GO:0045446	endothelial cell differentiation	1.250588e-3
GO:0045600	positive regulation of fat cell differentiation	1.255877e-3
GO:0042347	negative regulation of NF-kappaB import into nucleus	1.270648e-3
GO:0048712	negative regulation of astrocyte differentiation	1.282632e-3
GO:0050886	endocrine process	1.305739e-3
GO:0019370	leukotriene biosynthetic process	1.339361e-3
GO:0046058	cAMP metabolic process	1.357355e-3
GO:0014029	neural crest formation	1.377042e-3
GO:0014034	neural crest cell fate commitment	1.391024e-3
GO:0035644	phosphoanandamide dephosphorylation	1.404391e-3
GO:0032011	ARF protein signal transduction	1.404391e-3
GO:0045161	neuronal ion channel clustering	1.443054e-3
GO:0043537	negative regulation of blood vessel endothelial cell migration	1.443054e-3
GO:0014819	regulation of skeletal muscle contraction	1.445438e-3
GO:0043170	macromolecule metabolic process	1.458174e-3
GO:0042402	cellular biogenic amine catabolic process	1.469268e-3
GO:0015893	drug transport	1.474390e-3
GO:0002238	response to molecule of fungal origin	1.478314e-3
GO:0061015	snRNA import into nucleus	1.482363e-3
GO:0031591	wybutosine biosynthetic process	1.482363e-3
GO:0060442	branching involved in prostate gland morphogenesis	1.519328e-3
GO:0070555	response to interleukin-1	1.541505e-3
GO:0045071	negative regulation of viral genome replication	1.543276e-3
GO:0030155	regulation of cell adhesion	1.549942e-3
GO:0006415	translational termination	1.551255e-3
GO:0007614	short-term memory	1.554926e-3
GO:2000050	regulation of non-canonical Wnt receptor signaling pathway	1.560286e-3
GO:0050852	T cell receptor signaling pathway	1.566721e-3
GO:0060825	fibroblast growth factor receptor signaling pathway involved in neural plate anterior/posterior pattern formation	1.579501e-3
GO:0060302	negative regulation of cytokine activity	1.579501e-3
GO:2000313	regulation of fibroblast growth factor receptor signaling pathway involved in neural plate anterior/posterior pattern formation	1.579501e-3
GO:0002462	tolerance induction to nonself antigen	1.579501e-3
GO:0006844	acyl carnitine transport	1.579501e-3
GO:0015761	mannose transport	1.579501e-3
GO:0044242	cellular lipid catabolic process	1.582182e-3
GO:0060071	Wnt receptor signaling pathway, planar cell polarity pathway	1.598252e-3
GO:0002708	positive regulation of lymphocyte mediated immunity	1.602948e-3
GO:0071715	icosanoid transport	1.608898e-3
GO:0032854	positive regulation of Rap GTPase activity	1.612018e-3
GO:0002678	positive regulation of chronic inflammatory response	1.612018e-3
GO:0006874	cellular calcium ion homeostasis	1.620428e-3
GO:0043438	acetoacetic acid metabolic process	1.639195e-3
GO:0000302	response to reactive oxygen species	1.653507e-3
GO:0060049	regulation of protein glycosylation	1.662114e-3
GO:0002874	regulation of chronic inflammatory response to antigenic stimulus	1.662114e-3
GO:0006635	fatty acid beta-oxidation	1.675866e-3
GO:0048525	negative regulation of viral reproduction	1.681825e-3
GO:0045954	positive regulation of natural killer cell mediated cytotoxicity	1.690283e-3
GO:0006691	leukotriene metabolic process	1.690283e-3
GO:0001945	lymph vessel development	1.691269e-3
GO:0050728	negative regulation of inflammatory response	1.699415e-3
GO:0032663	regulation of interleukin-2 production	1.711786e-3
GO:0060343	trabecula formation	1.726297e-3
GO:0010811	positive regulation of cell-substrate adhesion	1.731613e-3
GO:0043056	forward locomotion	1.734996e-3
GO:0006491	N-glycan processing	1.749524e-3
GO:0072676	lymphocyte migration	1.767312e-3
GO:0021794	thalamus development	1.767312e-3
GO:0022612	gland morphogenesis	1.777515e-3
GO:0030204	chondroitin sulfate metabolic process	1.801652e-3
GO:2000173	negative regulation of branching morphogenesis of a nerve	1.809526e-3
GO:0033615	mitochondrial proton-transporting ATP synthase complex assembly	1.809526e-3
GO:0006547	histidine metabolic process	1.860531e-3
GO:0072028	nephron morphogenesis	1.871540e-3
GO:0045745	positive regulation of G-protein coupled receptor protein signaling pathway	1.923421e-3
GO:0008584	male gonad development	1.955600e-3
GO:0046903	secretion	1.958086e-3
GO:0072164	mesonephric tubule development	2.010063e-3
GO:0000462	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)	2.043255e-3
GO:0000079	regulation of cyclin-dependent protein kinase activity	2.078986e-3
GO:0007186	G-protein coupled receptor protein signaling pathway	2.084245e-3
GO:2000683	regulation of cellular response to X-ray	2.139593e-3
GO:0032048	cardiolipin metabolic process	2.167712e-3
GO:0022414	reproductive process	2.170601e-3
GO:0043567	regulation of insulin-like growth factor receptor signaling pathway	2.173061e-3
GO:0006643	membrane lipid metabolic process	2.197397e-3
GO:0070498	interleukin-1-mediated signaling pathway	2.214389e-3
GO:0014706	striated muscle tissue development	2.220725e-3
GO:0014911	positive regulation of smooth muscle cell migration	2.232438e-3
GO:0030261	chromosome condensation	2.249291e-3
GO:0044255	cellular lipid metabolic process	2.281322e-3
GO:0033137	negative regulation of peptidyl-serine phosphorylation	2.283159e-3
GO:0016042	lipid catabolic process	2.289653e-3
GO:0006997	nucleus organization	2.297292e-3
GO:0048639	positive regulation of developmental growth	2.300769e-3
GO:0021854	hypothalamus development	2.306897e-3
GO:0007585	respiratory gaseous exchange	2.380950e-3
GO:0002718	regulation of cytokine production involved in immune response	2.404939e-3
GO:0045994	positive regulation of translational initiation by iron	2.426095e-3
GO:0034116	positive regulation of heterotypic cell-cell adhesion	2.426095e-3
GO:0061048	negative regulation of branching involved in lung morphogenesis	2.426095e-3
GO:0006189	'de novo' IMP biosynthetic process	2.426095e-3
GO:0002037	negative regulation of L-glutamate transport	2.426095e-3
GO:0019752	carboxylic acid metabolic process	2.444914e-3
GO:0045213	neurotransmitter receptor metabolic process	2.460138e-3
GO:0071822	protein complex subunit organization	2.479442e-3
GO:0050678	regulation of epithelial cell proliferation	2.491086e-3
GO:0000003	reproduction	2.518986e-3
GO:0010638	positive regulation of organelle organization	2.559857e-3
GO:0042326	negative regulation of phosphorylation	2.561412e-3
GO:0048635	negative regulation of muscle organ development	2.591883e-3
GO:0032501	multicellular organismal process	2.602190e-3
GO:0051150	regulation of smooth muscle cell differentiation	2.612194e-3
GO:0002763	positive regulation of myeloid leukocyte differentiation	2.631307e-3
GO:0030857	negative regulation of epithelial cell differentiation	2.634433e-3
GO:0046879	hormone secretion	2.639702e-3
GO:0055074	calcium ion homeostasis	2.649270e-3
GO:0031400	negative regulation of protein modification process	2.653521e-3
GO:0070305	response to cGMP	2.654962e-3
GO:0032902	nerve growth factor production	2.654962e-3
GO:0060027	convergent extension involved in gastrulation	2.678435e-3
GO:0033979	box H/ACA snoRNA metabolic process	2.678435e-3
GO:0045162	clustering of voltage-gated sodium channels	2.698217e-3
GO:0071843	cellular component biogenesis at cellular level	2.726864e-3
GO:0072176	nephric duct development	2.741981e-3
GO:0060575	intestinal epithelial cell differentiation	2.755348e-3
GO:0046628	positive regulation of insulin receptor signaling pathway	2.755348e-3
GO:0009888	tissue development	2.769524e-3
GO:2000134	negative regulation of G1/S transition of mitotic cell cycle	2.800388e-3
GO:2000351	regulation of endothelial cell apoptosis	2.807369e-3
GO:0035335	peptidyl-tyrosine dephosphorylation	2.861679e-3
GO:0045989	positive regulation of striated muscle contraction	2.950832e-3
GO:0043486	histone exchange	2.991340e-3
GO:0006578	betaine biosynthetic process	2.991340e-3
GO:0051146	striated muscle cell differentiation	3.001737e-3
GO:0034698	response to gonadotropin stimulus	3.011303e-3
GO:0019695	choline metabolic process	3.019810e-3
GO:0060539	diaphragm development	3.037056e-3
GO:0060429	epithelium development	3.053491e-3
GO:0050732	negative regulation of peptidyl-tyrosine phosphorylation	3.067591e-3
GO:0031016	pancreas development	3.090508e-3
GO:0007281	germ cell development	3.115941e-3
GO:0039020	pronephric nephron tubule development	3.188040e-3
GO:0035565	regulation of pronephros size	3.188040e-3
GO:0060231	mesenchymal to epithelial transition	3.235073e-3
GO:0019674	NAD metabolic process	3.235073e-3
GO:0042180	cellular ketone metabolic process	3.252264e-3
GO:0071260	cellular response to mechanical stimulus	3.354884e-3
GO:0038028	insulin receptor signaling pathway via phosphatidylinositol 3-kinase cascade	3.369011e-3
GO:0016098	monoterpenoid metabolic process	3.372923e-3
GO:0002695	negative regulation of leukocyte activation	3.372930e-3
GO:0070561	vitamin D receptor signaling pathway	3.379851e-3
GO:0009605	response to external stimulus	3.387414e-3
GO:0035058	nonmotile primary cilium assembly	3.390959e-3
GO:0050729	positive regulation of inflammatory response	3.412079e-3
GO:0034440	lipid oxidation	3.413093e-3
GO:0060765	regulation of androgen receptor signaling pathway	3.438222e-3
GO:0046496	nicotinamide nucleotide metabolic process	3.469868e-3
GO:0060218	hemopoietic stem cell differentiation	3.480691e-3
GO:0009072	aromatic amino acid family metabolic process	3.491086e-3
GO:0050983	deoxyhypusine biosynthetic process from spermidine, using deoxyhypusine synthase	3.503302e-3
GO:0090104	pancreatic E cell differentiation	3.503302e-3
GO:0014878	response to electrical stimulus involved in regulation of muscle adaptation	3.503302e-3
GO:0003311	pancreatic D cell differentiation	3.503302e-3
GO:2000352	negative regulation of endothelial cell apoptosis	3.560114e-3
GO:0046546	development of primary male sexual characteristics	3.584544e-3
GO:0034614	cellular response to reactive oxygen species	3.592125e-3
GO:0007616	long-term memory	3.811656e-3
GO:0090305	nucleic acid phosphodiester bond hydrolysis	3.816517e-3
GO:0045936	negative regulation of phosphate metabolic process	3.949342e-3
GO:0046850	regulation of bone remodeling	3.962326e-3
GO:0046717	acid secretion	3.964947e-3
GO:0009956	radial pattern formation	4.031437e-3
GO:0006000	fructose metabolic process	4.045118e-3
GO:0032147	activation of protein kinase activity	4.055165e-3
GO:0021999	neural plate anterior/posterior regionalization	4.065516e-3
GO:0032232	negative regulation of actin filament bundle assembly	4.084852e-3
GO:0072181	mesonephric duct formation	4.114927e-3
GO:0002876	positive regulation of chronic inflammatory response to antigenic stimulus	4.114927e-3
GO:0031399	regulation of protein modification process	4.118577e-3
GO:0045163	clustering of voltage-gated potassium channels	4.168818e-3
GO:0032049	cardiolipin biosynthetic process	4.168818e-3
GO:0001933	negative regulation of protein phosphorylation	4.172125e-3
GO:0031650	regulation of heat generation	4.210857e-3
GO:0006629	lipid metabolic process	4.273094e-3
GO:0051354	negative regulation of oxidoreductase activity	4.281861e-3
GO:0050866	negative regulation of cell activation	4.284205e-3
GO:0071902	positive regulation of protein serine/threonine kinase activity	4.323701e-3
GO:0072079	nephron tubule formation	4.343849e-3
GO:0060986	endocrine hormone secretion	4.376227e-3
GO:0002700	regulation of production of molecular mediator of immune response	4.401590e-3
GO:0060261	positive regulation of transcription initiation from RNA polymerase II promoter	4.406751e-3
GO:0030850	prostate gland development	4.464525e-3
GO:0048729	tissue morphogenesis	4.504881e-3
GO:0071371	cellular response to gonadotropin stimulus	4.550274e-3
GO:0007379	segment specification	4.571332e-3
GO:0051235	maintenance of location	4.593350e-3
GO:0071732	cellular response to nitric oxide	4.594673e-3
GO:0002091	negative regulation of receptor internalization	4.622288e-3
GO:0043032	positive regulation of macrophage activation	4.645817e-3
GO:0070741	response to interleukin-6	4.657678e-3
GO:0032317	regulation of Rap GTPase activity	4.698325e-3
GO:0051029	rRNA transport	4.757342e-3
GO:0043068	positive regulation of programmed cell death	4.806224e-3
GO:0051250	negative regulation of lymphocyte activation	4.877321e-3
GO:0051270	regulation of cellular component movement	4.894916e-3
GO:0071379	cellular response to prostaglandin stimulus	5.065501e-3
GO:0071353	cellular response to interleukin-4	5.065501e-3
GO:0044070	regulation of anion transport	5.065501e-3
GO:0061383	trabecula morphogenesis	5.076010e-3
GO:0043461	proton-transporting ATP synthase complex assembly	5.098922e-3
GO:0071321	cellular response to cGMP	5.098922e-3
GO:0090092	regulation of transmembrane receptor protein serine/threonine kinase signaling pathway	5.159519e-3
GO:0055007	cardiac muscle cell differentiation	5.213457e-3
GO:0045932	negative regulation of muscle contraction	5.217948e-3
GO:0060051	negative regulation of protein glycosylation	5.226669e-3
GO:0046005	positive regulation of circadian sleep/wake cycle, REM sleep	5.226669e-3
GO:0033688	regulation of osteoblast proliferation	5.268744e-3
GO:0031349	positive regulation of defense response	5.270671e-3
GO:0006664	glycolipid metabolic process	5.349182e-3
GO:0090184	positive regulation of kidney development	5.357012e-3
GO:0070059	apoptosis in response to endoplasmic reticulum stress	5.357012e-3
GO:0035871	protein K11-linked deubiquitination	5.357801e-3
GO:2000002	negative regulation of DNA damage checkpoint	5.357801e-3
GO:0033315	meiotic cell cycle DNA replication checkpoint	5.357801e-3
GO:0060453	regulation of gastric acid secretion	5.357801e-3
GO:0022004	midbrain-hindbrain boundary maturation during brain development	5.357801e-3
GO:0021551	central nervous system morphogenesis	5.357801e-3
GO:0010032	meiotic chromosome condensation	5.357801e-3
GO:0021588	cerebellum formation	5.357801e-3
GO:0046434	organophosphate catabolic process	5.359463e-3
GO:0001658	branching involved in ureteric bud morphogenesis	5.458527e-3
GO:2000243	positive regulation of reproductive process	5.465137e-3
GO:0071205	protein localization to juxtaparanode region of axon	5.507116e-3
GO:0006705	mineralocorticoid biosynthetic process	5.507116e-3
GO:0044091	membrane biogenesis	5.507116e-3
GO:0032355	response to estradiol stimulus	5.581299e-3
GO:0009410	response to xenobiotic stimulus	5.605712e-3
GO:0007224	smoothened signaling pathway	5.680848e-3
GO:0002724	regulation of T cell cytokine production	5.720670e-3
GO:0071625	vocalization behavior	5.740465e-3
GO:0034097	response to cytokine stimulus	5.825942e-3
GO:0002702	positive regulation of production of molecular mediator of immune response	5.840001e-3
GO:0008366	axon ensheathment	5.840987e-3
GO:0061162	establishment of monopolar cell polarity	5.845815e-3
GO:0042254	ribosome biogenesis	5.960050e-3
GO:0023061	signal release	5.979906e-3
GO:0051651	maintenance of location in cell	5.979974e-3
GO:0033209	tumor necrosis factor-mediated signaling pathway	6.069793e-3
GO:0042421	norepinephrine biosynthetic process	6.104432e-3
GO:0033129	positive regulation of histone phosphorylation	6.157662e-3
GO:0018101	peptidyl-citrulline biosynthetic process from peptidyl-arginine	6.157662e-3
GO:0072503	cellular divalent inorganic cation homeostasis	6.168455e-3
GO:0071803	positive regulation of podosome assembly	6.176493e-3
GO:0031055	chromatin remodeling at centromere	6.176493e-3
GO:0070307	lens fiber cell development	6.220643e-3
GO:0002430	complement receptor mediated signaling pathway	6.229061e-3
GO:0008628	induction of apoptosis by hormones	6.229061e-3
GO:0045672	positive regulation of osteoclast differentiation	6.269714e-3
GO:0051953	negative regulation of amine transport	6.276571e-3