Novel motif:150

name:	motif150_AGCACAGGCG

Association to promoter expression in human samples<b>Summary:</b>Significance of the correlation with CAGE expression, human <br><b>Analyst:</b> Michiel de Hoon<br><br>link to source dataset <br>data

---

Association to promoter expression in mouse samples <b>Summary:</b>Significance of the correlation with CAGE expression, mouse <br><b>Analyst:</b> Michiel de Hoon<br><br>link to source dataset <br>data

---

GREAT analysis results for human <b>Summary:</b>Genomic Enrichment of Annotations Tool (GREAT, Nat Biotechnol. 2010 May;28(5):495-501) is used to identify, both in human and in mouse, the gene ontology terms of biological processes enriched given the predicted TFBSs, and evaluated the overlap in the top-500 gene ontology terms between human and mouse. For each novel motif, the P value for the overlap was then evaluated by calculating its relative rank with respect to this background distribution.<br>Analyst: Michiel de Hoon<br><br>link to source dataset <br>data

---

GO ID	GO Term	p-value
GO:0030262	apoptotic nuclear change	1.954373e-10
GO:0016480	negative regulation of transcription from RNA polymerase III promoter	1.971939e-10
GO:0006284	base-excision repair	2.879683e-10
GO:0006308	DNA catabolic process	1.847415e-9
GO:0006388	tRNA splicing, via endonucleolytic cleavage and ligation	2.933562e-9
GO:0060033	anatomical structure regression	5.320347e-9
GO:0090305	nucleic acid phosphodiester bond hydrolysis	3.164882e-8
GO:0006335	DNA replication-dependent nucleosome assembly	6.921605e-8
GO:0014040	positive regulation of Schwann cell differentiation	8.261430e-8
GO:0006285	base-excision repair, AP site formation	1.114840e-7
GO:0060381	positive regulation of single-stranded telomeric DNA binding	1.304548e-7
GO:0070574	cadmium ion transmembrane transport	1.788098e-7
GO:0034723	DNA replication-dependent nucleosome organization	3.123680e-7
GO:0090169	regulation of spindle assembly	3.891322e-7
GO:0090234	regulation of kinetochore assembly	3.891322e-7
GO:0071333	cellular response to glucose stimulus	4.608983e-7
GO:0008635	activation of caspase activity by cytochrome c	6.536693e-7
GO:0010624	regulation of Schwann cell proliferation	6.545832e-7
GO:0006828	manganese ion transport	6.562151e-7
GO:0052697	xenobiotic glucuronidation	1.057641e-6
GO:0070980	biphenyl catabolic process	1.057641e-6
GO:0052696	flavonoid glucuronidation	1.057641e-6
GO:0051552	flavone metabolic process	1.057641e-6
GO:0006789	bilirubin conjugation	1.057641e-6
GO:0010625	positive regulation of Schwann cell proliferation	1.131876e-6
GO:0042093	T-helper cell differentiation	1.353677e-6
GO:0007051	spindle organization	1.475147e-6
GO:0090343	positive regulation of cell aging	2.546170e-6
GO:0034214	protein hexamerization	2.735482e-6
GO:0018364	peptidyl-glutamine methylation	2.865747e-6
GO:0030488	tRNA methylation	2.976846e-6
GO:0014740	negative regulation of muscle hyperplasia	4.016141e-6
GO:0010225	response to UV-C	4.532286e-6
GO:2000002	negative regulation of DNA damage checkpoint	4.751384e-6
GO:0022004	midbrain-hindbrain boundary maturation during brain development	4.751384e-6
GO:0021551	central nervous system morphogenesis	4.751384e-6
GO:0021588	cerebellum formation	4.751384e-6
GO:0001522	pseudouridine synthesis	4.779772e-6
GO:0031442	positive regulation of mRNA 3'-end processing	5.204319e-6
GO:0009304	tRNA transcription	5.354776e-6
GO:0006359	regulation of transcription from RNA polymerase III promoter	6.193492e-6
GO:0006309	DNA fragmentation involved in apoptotic nuclear change	6.776604e-6
GO:0051926	negative regulation of calcium ion transport	7.641091e-6
GO:0048050	post-embryonic eye morphogenesis	7.991664e-6
GO:0040040	thermosensory behavior	8.807857e-6
GO:0006298	mismatch repair	9.117831e-6
GO:0014745	negative regulation of muscle adaptation	9.950553e-6
GO:0090230	regulation of centromere complex assembly	1.087641e-5
GO:0001678	cellular glucose homeostasis	1.149895e-5
GO:0090224	regulation of spindle organization	1.246165e-5
GO:0035793	positive regulation of metanephric mesenchymal cell migration by platelet-derived growth factor receptor-beta signaling pathway	1.261758e-5
GO:0035470	positive regulation of vascular wound healing	1.274407e-5
GO:0006117	acetaldehyde metabolic process	1.274407e-5
GO:0033590	response to cobalamin	1.274407e-5
GO:0046782	regulation of viral transcription	1.359927e-5
GO:0045007	depurination	1.621533e-5
GO:0002528	regulation of vascular permeability involved in acute inflammatory response	1.699556e-5
GO:0048752	semicircular canal morphogenesis	1.763526e-5
GO:0050434	positive regulation of viral transcription	2.075277e-5
GO:0030223	neutrophil differentiation	2.122942e-5
GO:0051225	spindle assembly	2.229139e-5
GO:0045063	T-helper 1 cell differentiation	2.246873e-5
GO:0008033	tRNA processing	2.257956e-5
GO:0046655	folic acid metabolic process	2.399589e-5
GO:0008334	histone mRNA metabolic process	2.419232e-5
GO:0021943	formation of radial glial scaffolds	2.627736e-5
GO:0006261	DNA-dependent DNA replication	2.649559e-5
GO:0071895	odontoblast differentiation	2.659231e-5
GO:0071322	cellular response to carbohydrate stimulus	3.093853e-5
GO:0070979	protein K11-linked ubiquitination	3.282593e-5
GO:0015804	neutral amino acid transport	3.496073e-5
GO:0016926	protein desumoylation	3.645745e-5
GO:0009804	coumarin metabolic process	3.800867e-5
GO:0006268	DNA unwinding involved in replication	3.832067e-5
GO:0030007	cellular potassium ion homeostasis	4.019139e-5
GO:0097039	protein linear polyubiquitination	4.158857e-5
GO:0008340	determination of adult lifespan	4.166440e-5
GO:0006646	phosphatidylethanolamine biosynthetic process	4.452842e-5
GO:0009264	deoxyribonucleotide catabolic process	4.521471e-5
GO:0002293	alpha-beta T cell differentiation involved in immune response	4.766355e-5
GO:0006423	cysteinyl-tRNA aminoacylation	4.854106e-5
GO:0070198	protein localization to chromosome, telomeric region	5.236128e-5
GO:0018343	protein farnesylation	5.685084e-5
GO:0042797	tRNA transcription from RNA polymerase III promoter	6.189598e-5
GO:0042791	5S class rRNA transcription from RNA polymerase III type 1 promoter	6.189598e-5
GO:0009438	methylglyoxal metabolic process	6.269070e-5
GO:0045794	negative regulation of cell volume	6.546146e-5
GO:0016241	regulation of macroautophagy	6.617003e-5
GO:0014738	regulation of muscle hyperplasia	6.937809e-5
GO:0033683	nucleotide-excision repair, DNA incision	7.297604e-5
GO:0035304	regulation of protein dephosphorylation	7.650445e-5
GO:0010511	regulation of phosphatidylinositol biosynthetic process	7.753536e-5
GO:0001302	replicative cell aging	8.402177e-5
GO:0018026	peptidyl-lysine monomethylation	9.264659e-5
GO:0002309	T cell proliferation involved in immune response	9.396774e-5
GO:0006264	mitochondrial DNA replication	9.581044e-5
GO:0060252	positive regulation of glial cell proliferation	9.610103e-5
GO:0032929	negative regulation of superoxide anion generation	9.944665e-5
GO:0045342	MHC class II biosynthetic process	1.038557e-4
GO:0070839	divalent metal ion export	1.038557e-4
GO:0043091	L-arginine import	1.038557e-4
GO:0032632	interleukin-3 production	1.038557e-4
GO:0006876	cellular cadmium ion homeostasis	1.038557e-4
GO:0015707	nitrite transport	1.038557e-4
GO:0000022	mitotic spindle elongation	1.051625e-4
GO:0002268	follicular dendritic cell differentiation	1.120280e-4
GO:0015789	UDP-N-acetylgalactosamine transport	1.174355e-4
GO:0015787	UDP-glucuronic acid transport	1.174355e-4
GO:0015680	intracellular copper ion transport	1.174355e-4
GO:0002357	defense response to tumor cell	1.174355e-4
GO:0006260	DNA replication	1.179121e-4
GO:0006281	DNA repair	1.223195e-4
GO:0070682	proteasome regulatory particle assembly	1.283405e-4
GO:0061153	trachea gland development	1.420518e-4
GO:0044265	cellular macromolecule catabolic process	1.454822e-4
GO:0006122	mitochondrial electron transport, ubiquinol to cytochrome c	1.476617e-4
GO:0006369	termination of RNA polymerase II transcription	1.510204e-4
GO:0071476	cellular hypotonic response	1.568428e-4
GO:0034633	retinol transport	1.580120e-4
GO:0018342	protein prenylation	1.616788e-4
GO:0010512	negative regulation of phosphatidylinositol biosynthetic process	1.616788e-4
GO:0019048	virus-host interaction	1.709705e-4
GO:0071585	detoxification of cadmium ion	1.817605e-4
GO:0001941	postsynaptic membrane organization	1.818947e-4
GO:2000194	regulation of female gonad development	1.886517e-4
GO:0009303	rRNA transcription	1.954944e-4
GO:0046796	viral genome transport in host cell	2.153113e-4
GO:0042053	regulation of dopamine metabolic process	2.170737e-4
GO:0072301	regulation of metanephric glomerular mesangial cell proliferation	2.177745e-4
GO:0060586	multicellular organismal iron ion homeostasis	2.177745e-4
GO:0050779	RNA destabilization	2.225038e-4
GO:0034470	ncRNA processing	2.240336e-4
GO:0002121	inter-male aggressive behavior	2.321426e-4
GO:0035372	protein localization to microtubule	2.475568e-4
GO:0032472	Golgi calcium ion transport	2.513985e-4
GO:0032468	Golgi calcium ion homeostasis	2.513985e-4
GO:0030026	cellular manganese ion homeostasis	2.513985e-4
GO:0044154	histone H3-K14 acetylation	2.533869e-4
GO:0071421	manganese ion transmembrane transport	2.556763e-4
GO:0051882	mitochondrial depolarization	2.609184e-4
GO:0006998	nuclear envelope organization	2.638113e-4
GO:0070816	phosphorylation of RNA polymerase II C-terminal domain	2.669548e-4
GO:0061157	mRNA destabilization	2.797709e-4
GO:0042998	positive regulation of Golgi to plasma membrane protein transport	2.797709e-4
GO:0010609	posttranscriptional regulation of gene expression by mRNA localization	2.797709e-4
GO:0021932	hindbrain radial glia guided cell migration	2.826159e-4
GO:0033687	osteoblast proliferation	2.930139e-4
GO:0060683	regulation of branching involved in salivary gland morphogenesis by epithelial-mesenchymal signaling	3.086525e-4
GO:0009698	phenylpropanoid metabolic process	3.201118e-4
GO:0051103	DNA ligation involved in DNA repair	3.312588e-4
GO:2000774	positive regulation of cellular senescence	3.318535e-4
GO:0035986	senescence-associated heterochromatin focus formation	3.318535e-4
GO:0010509	polyamine homeostasis	3.434338e-4
GO:0070831	basement membrane assembly	3.443813e-4
GO:0043149	stress fiber assembly	3.468427e-4
GO:2000195	negative regulation of female gonad development	3.518090e-4
GO:0006779	porphyrin-containing compound biosynthetic process	3.551720e-4
GO:0034660	ncRNA metabolic process	3.613398e-4
GO:0009262	deoxyribonucleotide metabolic process	3.674234e-4
GO:0046022	positive regulation of transcription from RNA polymerase II promoter during mitosis	3.747736e-4
GO:0035306	positive regulation of dephosphorylation	3.839363e-4
GO:0046184	aldehyde biosynthetic process	3.917158e-4
GO:0045851	pH reduction	4.006162e-4
GO:0035852	horizontal cell localization	4.028457e-4
GO:0035849	nephric duct elongation	4.028457e-4
GO:2000768	positive regulation of nephron tubule epithelial cell differentiation	4.028457e-4
GO:0042747	circadian sleep/wake cycle, REM sleep	4.028457e-4
GO:0035847	uterine epithelium development	4.028457e-4
GO:0035502	metanephric ureteric bud development	4.028457e-4
GO:0031118	rRNA pseudouridine synthesis	4.028457e-4
GO:0035846	oviduct epithelium development	4.028457e-4
GO:0042069	regulation of catecholamine metabolic process	4.029452e-4
GO:0008057	eye pigment granule organization	4.265904e-4
GO:0019242	methylglyoxal biosynthetic process	4.344477e-4
GO:0014707	branchiomeric skeletal muscle development	4.354282e-4
GO:0071071	regulation of phospholipid biosynthetic process	4.375469e-4
GO:0034465	response to carbon monoxide	4.434061e-4
GO:0060083	smooth muscle contraction involved in micturition	4.480208e-4
GO:0010507	negative regulation of autophagy	4.788533e-4
GO:0009812	flavonoid metabolic process	4.910772e-4
GO:0030520	estrogen receptor signaling pathway	4.928117e-4
GO:0032042	mitochondrial DNA metabolic process	5.023058e-4
GO:0045008	depyrimidination	5.394933e-4
GO:0006398	histone mRNA 3'-end processing	5.394933e-4
GO:0010610	regulation of mRNA stability involved in response to stress	5.556964e-4
GO:0035307	positive regulation of protein dephosphorylation	5.617050e-4
GO:0048524	positive regulation of viral reproduction	5.692590e-4
GO:0015781	pyrimidine nucleotide-sugar transport	5.761246e-4
GO:0045005	maintenance of fidelity involved in DNA-dependent DNA replication	5.914635e-4
GO:0071460	cellular response to cell-matrix adhesion	5.949404e-4
GO:0043921	modulation by host of viral transcription	6.085360e-4
GO:0019087	transformation of host cell by virus	6.327008e-4
GO:0006290	pyrimidine dimer repair	6.468637e-4
GO:0072110	glomerular mesangial cell proliferation	6.518275e-4
GO:0032471	reduction of endoplasmic reticulum calcium ion concentration	6.518275e-4
GO:0006295	nucleotide-excision repair, DNA incision, 3'-to lesion	6.600876e-4
GO:0045064	T-helper 2 cell differentiation	6.755688e-4
GO:0002315	marginal zone B cell differentiation	6.755688e-4
GO:0006405	RNA export from nucleus	7.499796e-4
GO:0021986	habenula development	7.503195e-4
GO:0051488	activation of anaphase-promoting complex activity	7.981861e-4
GO:0034502	protein localization to chromosome	8.179595e-4
GO:0017055	negative regulation of RNA polymerase II transcriptional preinitiation complex assembly	8.272899e-4
GO:0071072	negative regulation of phospholipid biosynthetic process	8.387550e-4
GO:0070212	protein poly-ADP-ribosylation	8.630687e-4
GO:0002418	immune response to tumor cell	8.749526e-4
GO:0023021	termination of signal transduction	9.337691e-4
GO:0060251	regulation of glial cell proliferation	9.441510e-4
GO:0006310	DNA recombination	1.012008e-3
GO:2000786	positive regulation of autophagic vacuole assembly	1.023116e-3
GO:0060242	contact inhibition	1.047452e-3
GO:0031297	replication fork processing	1.069949e-3
GO:0052312	modulation of transcription in other organism involved in symbiotic interaction	1.072522e-3
GO:0071899	negative regulation of estrogen receptor binding	1.072844e-3
GO:0000002	mitochondrial genome maintenance	1.080827e-3
GO:0032210	regulation of telomere maintenance via telomerase	1.081623e-3
GO:0060711	labyrinthine layer development	1.082135e-3
GO:0002679	respiratory burst involved in defense response	1.084786e-3
GO:0030302	deoxynucleotide transport	1.097469e-3
GO:0061050	regulation of cell growth involved in cardiac muscle cell development	1.097469e-3
GO:0002635	negative regulation of germinal center formation	1.097469e-3
GO:0010963	regulation of L-arginine import	1.115191e-3
GO:0051572	negative regulation of histone H3-K4 methylation	1.117931e-3
GO:0009223	pyrimidine deoxyribonucleotide catabolic process	1.117931e-3
GO:0014832	urinary bladder smooth muscle contraction	1.136191e-3
GO:0014038	regulation of Schwann cell differentiation	1.168211e-3
GO:0070988	demethylation	1.204445e-3
GO:0090303	positive regulation of wound healing	1.206274e-3
GO:0051452	intracellular pH reduction	1.254090e-3
GO:0019369	arachidonic acid metabolic process	1.255266e-3
GO:0045819	positive regulation of glycogen catabolic process	1.271929e-3
GO:0007256	activation of JNKK activity	1.287124e-3
GO:0031848	protection from non-homologous end joining at telomere	1.289684e-3
GO:0070875	positive regulation of glycogen metabolic process	1.300554e-3
GO:0035695	mitochondrion degradation by induced vacuole formation	1.332464e-3
GO:0006430	lysyl-tRNA aminoacylation	1.332464e-3
GO:0043367	CD4-positive, alpha-beta T cell differentiation	1.345137e-3
GO:0015809	arginine transport	1.350568e-3
GO:0090281	negative regulation of calcium ion import	1.373533e-3
GO:0007634	optokinetic behavior	1.373533e-3
GO:0071584	negative regulation of zinc ion import	1.373533e-3
GO:0031119	tRNA pseudouridine synthesis	1.373533e-3
GO:0019428	allantoin biosynthetic process	1.373533e-3
GO:0021599	abducens nerve formation	1.373533e-3
GO:0048702	embryonic neurocranium morphogenesis	1.435087e-3
GO:0071866	negative regulation of apoptosis in bone marrow	1.453838e-3
GO:0071864	positive regulation of cell proliferation in bone marrow	1.453838e-3
GO:0045199	maintenance of epithelial cell apical/basal polarity	1.550462e-3
GO:0060058	positive regulation of apoptosis involved in mammary gland involution	1.573579e-3
GO:0033013	tetrapyrrole metabolic process	1.595070e-3
GO:0006921	cellular component disassembly involved in apoptosis	1.597143e-3
GO:0035105	sterol regulatory element binding protein import into nucleus	1.622749e-3
GO:0002536	respiratory burst involved in inflammatory response	1.640186e-3
GO:0030423	targeting of mRNA for destruction involved in RNA interference	1.663365e-3
GO:0018022	peptidyl-lysine methylation	1.671695e-3
GO:0048597	post-embryonic camera-type eye morphogenesis	1.693140e-3
GO:0051089	constitutive protein ectodomain proteolysis	1.693140e-3
GO:0046674	induction of retinal programmed cell death	1.693140e-3
GO:0042941	D-alanine transport	1.693140e-3
GO:0002352	B cell negative selection	1.693140e-3
GO:0032976	release of matrix enzymes from mitochondria	1.693140e-3
GO:0001777	T cell homeostatic proliferation	1.693140e-3
GO:0051028	mRNA transport	1.697743e-3
GO:0051102	DNA ligation involved in DNA recombination	1.712303e-3
GO:0019413	acetate biosynthetic process	1.712303e-3
GO:0046380	N-acetylneuraminate biosynthetic process	1.712303e-3
GO:0019542	propionate biosynthetic process	1.712303e-3
GO:0035644	phosphoanandamide dephosphorylation	1.712303e-3
GO:0000154	rRNA modification	1.712872e-3
GO:0031507	heterochromatin formation	1.717244e-3
GO:0035356	cellular triglyceride homeostasis	1.750823e-3
GO:0071335	hair follicle cell proliferation	1.768351e-3
GO:0032290	peripheral nervous system myelin formation	1.768351e-3
GO:0060339	negative regulation of type I interferon-mediated signaling pathway	1.794309e-3
GO:0060318	definitive erythrocyte differentiation	1.820596e-3
GO:0006778	porphyrin-containing compound metabolic process	1.831117e-3
GO:0043928	exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay	1.837965e-3
GO:0022411	cellular component disassembly	1.855251e-3
GO:0070886	positive regulation of calcineurin-NFAT signaling pathway	1.948699e-3
GO:0040030	regulation of molecular function, epigenetic	1.948699e-3
GO:0045074	regulation of interleukin-10 biosynthetic process	1.956982e-3
GO:0006406	mRNA export from nucleus	2.006593e-3
GO:0071353	cellular response to interleukin-4	2.073379e-3
GO:0006399	tRNA metabolic process	2.168974e-3
GO:0030433	ER-associated protein catabolic process	2.206937e-3
GO:0071472	cellular response to salt stress	2.216127e-3
GO:0043089	positive regulation of Cdc42 GTPase activity	2.270546e-3
GO:0060073	micturition	2.283620e-3
GO:0007339	binding of sperm to zona pellucida	2.290365e-3
GO:0043983	histone H4-K12 acetylation	2.297174e-3
GO:0035090	maintenance of apical/basal cell polarity	2.511591e-3
GO:0051898	negative regulation of protein kinase B signaling cascade	2.524838e-3
GO:0031536	positive regulation of exit from mitosis	2.560770e-3
GO:0046314	phosphocreatine biosynthetic process	2.569481e-3
GO:0070873	regulation of glycogen metabolic process	2.584368e-3
GO:0007196	inhibition of adenylate cyclase activity by metabotropic glutamate receptor signaling pathway	2.601153e-3
GO:0006266	DNA ligation	2.616053e-3
GO:0071340	skeletal muscle nicotinic acetylcholine receptor clustering	2.635596e-3
GO:0046607	positive regulation of centrosome cycle	2.635596e-3
GO:0000956	nuclear-transcribed mRNA catabolic process	2.653927e-3
GO:0072302	negative regulation of metanephric glomerular mesangial cell proliferation	2.655670e-3
GO:0071477	cellular hypotonic salinity response	2.655670e-3
GO:0061032	visceral serous pericardium development	2.655670e-3
GO:0016266	O-glycan processing	2.655670e-3
GO:0071845	cellular component disassembly at cellular level	2.667091e-3
GO:0045415	negative regulation of interleukin-8 biosynthetic process	2.681803e-3
GO:0006296	nucleotide-excision repair, DNA incision, 5'-to lesion	2.681803e-3
GO:0051497	negative regulation of stress fiber assembly	2.703210e-3
GO:0002286	T cell activation involved in immune response	2.768472e-3
GO:0051438	regulation of ubiquitin-protein ligase activity	2.789775e-3
GO:0000720	pyrimidine dimer repair by nucleotide-excision repair	2.834040e-3
GO:0065001	specification of axis polarity	2.886393e-3
GO:2000753	positive regulation of glucosylceramide catabolic process	2.897111e-3
GO:2000755	positive regulation of sphingomyelin catabolic process	2.897111e-3
GO:0002291	T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell	2.897111e-3
GO:0046628	positive regulation of insulin receptor signaling pathway	2.906691e-3
GO:0033058	directional locomotion	2.968325e-3
GO:0072166	posterior mesonephric tubule development	2.980261e-3
GO:0055026	negative regulation of cardiac muscle tissue development	2.980261e-3
GO:0034198	cellular response to amino acid starvation	2.980261e-3
GO:0060020	Bergmann glial cell differentiation	3.038403e-3
GO:0014848	urinary tract smooth muscle contraction	3.058185e-3
GO:0072321	chaperone-mediated protein transport	3.073474e-3
GO:0070213	protein auto-ADP-ribosylation	3.073474e-3
GO:0048069	eye pigmentation	3.080531e-3
GO:0060216	definitive hemopoiesis	3.253506e-3
GO:0032298	positive regulation of DNA-dependent DNA replication initiation	3.308631e-3
GO:0003094	glomerular filtration	3.308631e-3
GO:0021592	fourth ventricle development	3.312794e-3
GO:0043923	positive regulation by host of viral transcription	3.319289e-3
GO:0007257	activation of JUN kinase activity	3.371229e-3
GO:0002562	somatic diversification of immune receptors via germline recombination within a single locus	3.540170e-3
GO:0060061	Spemann organizer formation	3.541808e-3
GO:0072124	regulation of glomerular mesangial cell proliferation	3.567770e-3
GO:0043604	amide biosynthetic process	3.568225e-3
GO:0070670	response to interleukin-4	3.751468e-3
GO:0006244	pyrimidine nucleotide catabolic process	3.786668e-3
GO:0042760	very long-chain fatty acid catabolic process	3.882730e-3
GO:0006304	DNA modification	3.895095e-3
GO:0043967	histone H4 acetylation	3.901377e-3
GO:0035873	lactate transmembrane transport	3.905969e-3
GO:0010070	zygote asymmetric cell division	3.905969e-3
GO:0030037	actin filament reorganization involved in cell cycle	3.950404e-3
GO:0006370	mRNA capping	3.984914e-3
GO:0060213	positive regulation of nuclear-transcribed mRNA poly(A) tail shortening	4.031957e-3
GO:0035357	peroxisome proliferator activated receptor signaling pathway	4.227035e-3
GO:0030264	nuclear fragmentation involved in apoptotic nuclear change	4.245321e-3
GO:0035752	lysosomal lumen pH elevation	4.245321e-3
GO:0043181	vacuolar sequestering	4.245321e-3
GO:0051463	negative regulation of cortisol secretion	4.245321e-3
GO:0010477	response to sulfur dioxide	4.245321e-3
GO:0060125	negative regulation of growth hormone secretion	4.245321e-3
GO:0005985	sucrose metabolic process	4.245321e-3
GO:0000046	autophagic vacuole fusion	4.245321e-3
GO:0000023	maltose metabolic process	4.245321e-3
GO:0001575	globoside metabolic process	4.245321e-3
GO:0002457	T cell antigen processing and presentation	4.245321e-3
GO:0018293	protein-FAD linkage	4.249124e-3
GO:0060876	semicircular canal formation	4.249124e-3
GO:0006391	transcription initiation from mitochondrial promoter	4.249124e-3
GO:0006121	mitochondrial electron transport, succinate to ubiquinone	4.249124e-3
GO:0043467	regulation of generation of precursor metabolites and energy	4.254441e-3
GO:0043161	proteasomal ubiquitin-dependent protein catabolic process	4.286012e-3
GO:0006707	cholesterol catabolic process	4.386530e-3
GO:0017004	cytochrome complex assembly	4.408349e-3
GO:0003406	retinal pigment epithelium development	4.408349e-3
GO:0001835	blastocyst hatching	4.423820e-3
GO:0033505	floor plate morphogenesis	4.456602e-3
GO:0006288	base-excision repair, DNA ligation	4.456602e-3
GO:0006270	DNA-dependent DNA replication initiation	4.497792e-3
GO:0043153	entrainment of circadian clock by photoperiod	4.548475e-3
GO:0021562	vestibulocochlear nerve development	4.548475e-3
GO:0051580	regulation of neurotransmitter uptake	4.565768e-3
GO:0032606	type I interferon production	4.567733e-3
GO:0060005	vestibular reflex	4.576494e-3
GO:0034766	negative regulation of ion transmembrane transport	4.647759e-3
GO:0070537	histone H2A K63-linked deubiquitination	4.697359e-3
GO:0043966	histone H3 acetylation	4.721995e-3
GO:0072109	glomerular mesangium development	4.817998e-3
GO:0071105	response to interleukin-11	4.985945e-3
GO:0080009	mRNA methylation	4.985945e-3
GO:0070179	D-serine biosynthetic process	4.985945e-3
GO:0031619	homologous chromosome orientation involved in meiotic metaphase I plate congression	4.985945e-3
GO:0014908	myotube differentiation involved in skeletal muscle regeneration	4.985945e-3
GO:0006289	nucleotide-excision repair	5.184445e-3
GO:0072366	regulation of cellular ketone metabolic process by positive regulation of transcription from RNA polymerase II promoter	5.227600e-3
GO:0022007	convergent extension involved in neural plate elongation	5.227600e-3
GO:0072363	regulation of glycolysis by positive regulation of transcription from RNA polymerase II promoter	5.227600e-3
GO:0009133	nucleoside diphosphate biosynthetic process	5.326887e-3
GO:0009155	purine deoxyribonucleotide catabolic process	5.340519e-3
GO:0032232	negative regulation of actin filament bundle assembly	5.413835e-3
GO:0032836	glomerular basement membrane development	5.564726e-3
GO:0090174	organelle membrane fusion	5.587922e-3
GO:0000038	very long-chain fatty acid metabolic process	5.791534e-3
GO:0006491	N-glycan processing	5.943495e-3
GO:0090275	negative regulation of somatostatin secretion	5.983765e-3
GO:0005997	xylulose metabolic process	5.993829e-3
GO:0043482	cellular pigment accumulation	6.048187e-3
GO:0043476	pigment accumulation	6.048187e-3
GO:0033540	fatty acid beta-oxidation using acyl-CoA oxidase	6.180604e-3
GO:0010994	free ubiquitin chain polymerization	6.212075e-3
GO:0046365	monosaccharide catabolic process	6.320223e-3
GO:0035036	sperm-egg recognition	6.332501e-3
GO:0043985	histone H4-R3 methylation	6.338798e-3
GO:0048341	paraxial mesoderm formation	6.392157e-3
GO:0051457	maintenance of protein location in nucleus	6.436250e-3
GO:0042420	dopamine catabolic process	6.447399e-3
GO:0010498	proteasomal protein catabolic process	6.603273e-3
GO:0070734	histone H3-K27 methylation	6.669094e-3
GO:0071506	cellular response to mycophenolic acid	6.684003e-3
GO:0072126	positive regulation of glomerular mesangial cell proliferation	6.684003e-3
GO:0015936	coenzyme A metabolic process	6.722955e-3
GO:0018027	peptidyl-lysine dimethylation	6.804701e-3
GO:0044088	regulation of vacuole organization	6.815515e-3
GO:0071394	cellular response to testosterone stimulus	6.815515e-3
GO:0070625	zymogen granule exocytosis	6.853133e-3
GO:0046604	positive regulation of mitotic centrosome separation	6.853133e-3
GO:0014895	smooth muscle hypertrophy	6.853133e-3
GO:0003106	negative regulation of glomerular filtration by angiotensin	6.853133e-3
GO:0006742	NADP catabolic process	6.853133e-3
GO:0031440	regulation of mRNA 3'-end processing	6.857439e-3
GO:0061179	negative regulation of insulin secretion involved in cellular response to glucose stimulus	6.925106e-3
GO:0009451	RNA modification	6.942319e-3
GO:0060872	semicircular canal development	6.987824e-3
GO:0060830	ciliary receptor clustering involved in smoothened signaling pathway	7.091967e-3
GO:0072285	mesenchymal to epithelial transition involved in metanephric renal vesicle formation	7.091967e-3
GO:0060248	detection of cell density by contact stimulus involved in contact inhibition	7.091967e-3
GO:0045358	negative regulation of interferon-beta biosynthetic process	7.091967e-3
GO:0007371	ventral midline determination	7.091967e-3
GO:0046670	positive regulation of retinal cell programmed cell death	7.091967e-3
GO:0009186	deoxyribonucleoside diphosphate metabolic process	7.134124e-3
GO:0000422	mitochondrion degradation	7.281098e-3
GO:0000710	meiotic mismatch repair	7.281098e-3
GO:0060821	inactivation of X chromosome by DNA methylation	7.333466e-3
GO:0048561	establishment of organ orientation	7.333466e-3
GO:0042335	cuticle development	7.333466e-3
GO:0035710	CD4-positive, alpha-beta T cell activation	7.566089e-3
GO:0034699	response to luteinizing hormone stimulus	7.655332e-3
GO:2000466	negative regulation of glycogen (starch) synthase activity	7.763619e-3
GO:0032205	negative regulation of telomere maintenance	7.769655e-3
GO:0032790	ribosome disassembly	7.796327e-3
GO:0042218	1-aminocyclopropane-1-carboxylate biosynthetic process	7.820618e-3
GO:0042424	catecholamine catabolic process	7.890210e-3
GO:2000210	positive regulation of anoikis	7.963251e-3
GO:0060713	labyrinthine layer morphogenesis	8.026671e-3
GO:0007288	sperm axoneme assembly	8.169793e-3
GO:0072298	regulation of metanephric glomerulus development	8.223264e-3
GO:0043280	positive regulation of caspase activity	8.458890e-3
GO:0007035	vacuolar acidification	8.471455e-3
GO:0045402	regulation of interleukin-4 biosynthetic process	8.566221e-3
GO:0043555	regulation of translation in response to stress	8.626248e-3
GO:0051444	negative regulation of ubiquitin-protein ligase activity	8.642271e-3
GO:0060561	apoptosis involved in morphogenesis	8.778663e-3
GO:0061360	optic chiasma development	8.820105e-3
GO:2000597	positive regulation of optic nerve formation	8.820105e-3
GO:0046416	D-amino acid metabolic process	8.820105e-3
GO:0021650	vestibulocochlear nerve formation	8.820105e-3
GO:0021633	optic nerve structural organization	8.820105e-3
GO:0035799	ureter maturation	8.820105e-3
GO:0007020	microtubule nucleation	8.930203e-3
GO:0042593	glucose homeostasis	9.008704e-3
GO:0035511	oxidative DNA demethylation	9.036133e-3
GO:0072081	specification of nephron tubule identity	9.038204e-3
GO:0000415	negative regulation of histone H3-K36 methylation	9.156418e-3
GO:0046580	negative regulation of Ras protein signal transduction	9.194308e-3
GO:0050685	positive regulation of mRNA processing	9.459374e-3
GO:0006283	transcription-coupled nucleotide-excision repair	9.468972e-3
GO:0042088	T-helper 1 type immune response	9.493576e-3
GO:0006390	transcription from mitochondrial promoter	9.561433e-3
GO:2000311	regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor activity	9.850413e-3
GO:0070173	regulation of enamel mineralization	9.894574e-3
GO:0018283	iron incorporation into metallo-sulfur cluster	9.942600e-3
GO:0018125	peptidyl-cysteine methylation	9.942600e-3
GO:0072364	regulation of cellular ketone metabolic process by regulation of transcription from RNA polymerase II promoter	9.996767e-3
GO:0090342	regulation of cell aging	1.010178e-2
GO:0090307	spindle assembly involved in mitosis	1.010908e-2
GO:0042552	myelination	1.019328e-2
GO:0015696	ammonium transport	1.026204e-2
GO:0031146	SCF-dependent proteasomal ubiquitin-dependent protein catabolic process	1.042670e-2
GO:0030422	production of siRNA involved in RNA interference	1.051357e-2
GO:0035264	multicellular organism growth	1.054208e-2
GO:0072262	metanephric glomerular mesangial cell proliferation involved in metanephros development	1.063267e-2
GO:0009452	RNA capping	1.070026e-2
GO:0060347	heart trabecula formation	1.092463e-2
GO:0010458	exit from mitosis	1.092880e-2
GO:0048291	isotype switching to IgG isotypes	1.107508e-2
GO:0015919	peroxisomal membrane transport	1.107508e-2
GO:0090324	negative regulation of oxidative phosphorylation	1.107508e-2
GO:0000056	ribosomal small subunit export from nucleus	1.107508e-2
GO:0002368	B cell cytokine production	1.107508e-2
GO:0002842	positive regulation of T cell mediated immune response to tumor cell	1.107508e-2
GO:0010255	glucose mediated signaling pathway	1.107508e-2
GO:0006868	glutamine transport	1.119782e-2
GO:0060976	coronary vasculature development	1.135346e-2
GO:0010889	regulation of sequestering of triglyceride	1.135346e-2
GO:0051156	glucose 6-phosphate metabolic process	1.141007e-2
GO:0009394	2'-deoxyribonucleotide metabolic process	1.148061e-2
GO:0035791	platelet-derived growth factor receptor-beta signaling pathway	1.148185e-2
GO:0002086	diaphragm contraction	1.162517e-2
GO:0035022	positive regulation of Rac protein signal transduction	1.162517e-2

GREAT analysis results for mouseGenomic Enrichment of Annotations Tool (GREAT, Nat Biotechnol. 2010 May;28(5):495-501) is used to identify, both in human and in mouse, the gene ontology terms of biological processes enriched given the predicted TFBSs, and evaluated the overlap in the top-500 gene ontology terms between human and mouse. For each novel motif, the P value for the overlap was then evaluated by calculating its relative rank with respect to this background distribution.<br>Analyst: Michiel de Hoon <br><br>link to source dataset <br>data

---

GO ID	GO Term	p-value
GO:0022403	cell cycle phase	6.444340e-11
GO:0000278	mitotic cell cycle	5.110736e-9
GO:0022402	cell cycle process	2.401500e-8
GO:0000279	M phase	4.449590e-8
GO:0032367	intracellular cholesterol transport	4.727128e-8
GO:0021549	cerebellum development	1.465536e-7
GO:0071394	cellular response to testosterone stimulus	1.625207e-7
GO:0007049	cell cycle	3.679798e-7
GO:0045585	positive regulation of cytotoxic T cell differentiation	3.898081e-7
GO:0035520	monoubiquitinated protein deubiquitination	9.260844e-7
GO:0006139	nucleobase-containing compound metabolic process	1.029391e-6
GO:0010467	gene expression	1.046389e-6
GO:0045841	negative regulation of mitotic metaphase/anaphase transition	1.183995e-6
GO:0022037	metencephalon development	1.770870e-6
GO:0045647	negative regulation of erythrocyte differentiation	1.887438e-6
GO:0071174	mitotic cell cycle spindle checkpoint	2.785409e-6
GO:0042273	ribosomal large subunit biogenesis	2.986380e-6
GO:0045351	type I interferon biosynthetic process	3.255292e-6
GO:0016226	iron-sulfur cluster assembly	3.378070e-6
GO:0042747	circadian sleep/wake cycle, REM sleep	3.605670e-6
GO:0006448	regulation of translational elongation	3.822676e-6
GO:0032365	intracellular lipid transport	3.968165e-6
GO:0071168	protein localization to chromatin	5.375066e-6
GO:0043949	regulation of cAMP-mediated signaling	5.553611e-6
GO:0006540	glutamate decarboxylation to succinate	5.776761e-6
GO:0000087	M phase of mitotic cell cycle	5.955187e-6
GO:0071169	establishment of protein localization to chromatin	7.116541e-6
GO:0045358	negative regulation of interferon-beta biosynthetic process	7.116541e-6
GO:0015966	diadenosine tetraphosphate biosynthetic process	7.116541e-6
GO:0007094	mitotic cell cycle spindle assembly checkpoint	7.221313e-6
GO:0032784	regulation of transcription elongation, DNA-dependent	8.898993e-6
GO:0006105	succinate metabolic process	9.720049e-6
GO:0032968	positive regulation of transcription elongation from RNA polymerase II promoter	1.033047e-5
GO:0090304	nucleic acid metabolic process	1.262267e-5
GO:0021695	cerebellar cortex development	1.467040e-5
GO:0007067	mitosis	1.489366e-5
GO:0031577	spindle checkpoint	1.495747e-5
GO:0010950	positive regulation of endopeptidase activity	1.612381e-5
GO:0021562	vestibulocochlear nerve development	1.689360e-5
GO:0006391	transcription initiation from mitochondrial promoter	2.135213e-5
GO:0006412	translation	2.205313e-5
GO:0048285	organelle fission	2.531179e-5
GO:0007422	peripheral nervous system development	2.847408e-5
GO:0043973	histone H3-K4 acetylation	3.341299e-5
GO:0061360	optic chiasma development	3.341299e-5
GO:2000597	positive regulation of optic nerve formation	3.341299e-5
GO:0046985	positive regulation of hemoglobin biosynthetic process	3.341299e-5
GO:0000972	transcription-dependent tethering of RNA polymerase II gene DNA at nuclear periphery	3.341299e-5
GO:0021633	optic nerve structural organization	3.341299e-5
GO:0021650	vestibulocochlear nerve formation	3.341299e-5
GO:0035799	ureter maturation	3.341299e-5
GO:0048793	pronephros development	3.784047e-5
GO:0070368	positive regulation of hepatocyte differentiation	4.123057e-5
GO:0017156	calcium ion-dependent exocytosis	4.494666e-5
GO:0032717	negative regulation of interleukin-8 production	4.711836e-5
GO:0042998	positive regulation of Golgi to plasma membrane protein transport	4.777201e-5
GO:0017196	N-terminal peptidyl-methionine acetylation	4.777201e-5
GO:0045963	negative regulation of dopamine metabolic process	5.342377e-5
GO:0050668	positive regulation of homocysteine metabolic process	5.342377e-5
GO:0034641	cellular nitrogen compound metabolic process	5.858791e-5
GO:0072040	negative regulation of mesenchymal stem cell apoptosis involved in nephron morphogenesis	7.399216e-5
GO:0016578	histone deubiquitination	7.810872e-5
GO:0016445	somatic diversification of immunoglobulins	9.345237e-5
GO:0043457	regulation of cellular respiration	1.004278e-4
GO:0006290	pyrimidine dimer repair	1.099537e-4
GO:0000959	mitochondrial RNA metabolic process	1.111759e-4
GO:0006473	protein acetylation	1.182726e-4
GO:0000080	G1 phase of mitotic cell cycle	1.209646e-4
GO:0072177	mesonephric duct development	1.231594e-4
GO:0051276	chromosome organization	1.431996e-4
GO:0046605	regulation of centrosome cycle	1.482307e-4
GO:0021697	cerebellar cortex formation	1.634723e-4
GO:0021702	cerebellar Purkinje cell differentiation	1.687089e-4
GO:0008334	histone mRNA metabolic process	1.791466e-4
GO:0051329	interphase of mitotic cell cycle	1.820830e-4
GO:0072162	metanephric mesenchymal cell differentiation	1.837161e-4
GO:0006807	nitrogen compound metabolic process	1.837535e-4
GO:0071173	spindle assembly checkpoint	1.919994e-4
GO:0048291	isotype switching to IgG isotypes	2.104419e-4
GO:0071624	positive regulation of granulocyte chemotaxis	2.104419e-4
GO:0048239	negative regulation of DNA recombination at telomere	2.104419e-4
GO:0002368	B cell cytokine production	2.104419e-4
GO:0006430	lysyl-tRNA aminoacylation	2.104419e-4
GO:0046452	dihydrofolate metabolic process	2.104419e-4
GO:0043543	protein acylation	2.128515e-4
GO:0055099	response to high density lipoprotein particle stimulus	2.164536e-4
GO:0016447	somatic recombination of immunoglobulin gene segments	2.186391e-4
GO:0001844	protein insertion into mitochondrial membrane involved in induction of apoptosis	2.380613e-4
GO:0021696	cerebellar cortex morphogenesis	2.401895e-4
GO:0042996	regulation of Golgi to plasma membrane protein transport	2.409279e-4
GO:0030512	negative regulation of transforming growth factor beta receptor signaling pathway	2.433840e-4
GO:0009396	folic acid-containing compound biosynthetic process	2.539882e-4
GO:2000594	positive regulation of metanephric DCT cell differentiation	2.555634e-4
GO:0072305	negative regulation of mesenchymal stem cell apoptosis involved in metanephric nephron morphogenesis	2.555634e-4
GO:0039003	pronephric field specification	2.555634e-4
GO:0014037	Schwann cell differentiation	2.593598e-4
GO:0021794	thalamus development	2.731739e-4
GO:0045839	negative regulation of mitosis	2.939824e-4
GO:0060319	primitive erythrocyte differentiation	3.012899e-4
GO:0000083	regulation of transcription involved in G1/S phase of mitotic cell cycle	3.067375e-4
GO:0030902	hindbrain development	3.090627e-4
GO:0016070	RNA metabolic process	3.112125e-4
GO:0050689	negative regulation of defense response to virus by host	3.181687e-4
GO:0032456	endocytic recycling	3.383166e-4
GO:0006474	N-terminal protein amino acid acetylation	3.401329e-4
GO:0051325	interphase	3.695146e-4
GO:0031581	hemidesmosome assembly	3.988187e-4
GO:0007340	acrosome reaction	4.050279e-4
GO:0030421	defecation	4.092907e-4
GO:0072003	kidney rudiment formation	4.100603e-4
GO:0032922	circadian regulation of gene expression	4.327187e-4
GO:0071872	cellular response to epinephrine stimulus	4.419052e-4
GO:0006482	protein demethylation	4.431982e-4
GO:0045875	negative regulation of sister chromatid cohesion	4.526258e-4
GO:0042136	neurotransmitter biosynthetic process	4.555501e-4
GO:0009258	10-formyltetrahydrofolate catabolic process	4.594063e-4
GO:0016926	protein desumoylation	4.899103e-4
GO:0009452	RNA capping	4.946790e-4
GO:0070076	histone lysine demethylation	5.061380e-4
GO:0007059	chromosome segregation	5.158703e-4
GO:0060620	regulation of cholesterol import	5.526490e-4
GO:0030071	regulation of mitotic metaphase/anaphase transition	5.755683e-4
GO:0009082	branched chain family amino acid biosynthetic process	5.948098e-4
GO:0034502	protein localization to chromosome	6.288897e-4
GO:0051436	negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle	6.370232e-4
GO:0006760	folic acid-containing compound metabolic process	6.567301e-4
GO:0015986	ATP synthesis coupled proton transport	6.653656e-4
GO:0016574	histone ubiquitination	6.831847e-4
GO:0042559	pteridine-containing compound biosynthetic process	7.145729e-4
GO:0051445	regulation of meiotic cell cycle	7.402860e-4
GO:0006402	mRNA catabolic process	7.523932e-4
GO:0090267	positive regulation of mitotic cell cycle spindle assembly checkpoint	7.664206e-4
GO:0009648	photoperiodism	7.664206e-4
GO:0006780	uroporphyrinogen III biosynthetic process	7.694819e-4
GO:0042428	serotonin metabolic process	8.356274e-4
GO:0006829	zinc ion transport	8.499830e-4
GO:0031365	N-terminal protein amino acid modification	9.462280e-4
GO:0032874	positive regulation of stress-activated MAPK cascade	9.491953e-4
GO:0010972	negative regulation of G2/M transition of mitotic cell cycle	9.611798e-4
GO:0042558	pteridine-containing compound metabolic process	9.911507e-4
GO:0000027	ribosomal large subunit assembly	1.069152e-3
GO:0072161	mesenchymal cell differentiation involved in kidney development	1.075715e-3
GO:0010564	regulation of cell cycle process	1.109243e-3
GO:0080164	regulation of nitric oxide metabolic process	1.144298e-3
GO:0016482	cytoplasmic transport	1.144298e-3
GO:0017187	peptidyl-glutamic acid carboxylation	1.144298e-3
GO:0031572	G2/M transition DNA damage checkpoint	1.170814e-3
GO:0033025	regulation of mast cell apoptosis	1.180450e-3
GO:0001832	blastocyst growth	1.204172e-3
GO:0003406	retinal pigment epithelium development	1.225785e-3
GO:0006471	protein ADP-ribosylation	1.236995e-3
GO:0043525	positive regulation of neuron apoptosis	1.242008e-3
GO:0018205	peptidyl-lysine modification	1.295777e-3
GO:0000463	maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)	1.333982e-3
GO:0016573	histone acetylation	1.346218e-3
GO:0051225	spindle assembly	1.380382e-3
GO:0046847	filopodium assembly	1.382147e-3
GO:0021587	cerebellum morphogenesis	1.390172e-3
GO:0071422	succinate transmembrane transport	1.392196e-3
GO:0016568	chromatin modification	1.408151e-3
GO:0051835	positive regulation of synapse structural plasticity	1.412479e-3
GO:0001672	regulation of chromatin assembly or disassembly	1.419108e-3
GO:0070544	histone H3-K36 demethylation	1.430920e-3
GO:0051894	positive regulation of focal adhesion assembly	1.437015e-3
GO:0042053	regulation of dopamine metabolic process	1.437015e-3
GO:0060621	negative regulation of cholesterol import	1.446750e-3
GO:0072176	nephric duct development	1.503713e-3
GO:0034645	cellular macromolecule biosynthetic process	1.521112e-3
GO:0031576	G2/M transition checkpoint	1.538541e-3
GO:0010989	negative regulation of low-density lipoprotein particle clearance	1.608457e-3
GO:2000505	regulation of energy homeostasis	1.685587e-3
GO:0000956	nuclear-transcribed mRNA catabolic process	1.691899e-3
GO:0051204	protein insertion into mitochondrial membrane	1.699839e-3
GO:0032606	type I interferon production	1.727978e-3
GO:0032205	negative regulation of telomere maintenance	1.767933e-3
GO:0010948	negative regulation of cell cycle process	1.785580e-3
GO:0006513	protein monoubiquitination	1.795409e-3
GO:0046984	regulation of hemoglobin biosynthetic process	1.889069e-3
GO:0045918	negative regulation of cytolysis	1.889069e-3
GO:0051661	maintenance of centrosome location	1.947465e-3
GO:0018214	protein carboxylation	1.947465e-3
GO:0018009	N-terminal peptidyl-L-cysteine N-palmitoylation	1.947465e-3
GO:0021903	rostrocaudal neural tube patterning	1.957333e-3
GO:0072178	nephric duct morphogenesis	1.980198e-3
GO:0051549	positive regulation of keratinocyte migration	2.000091e-3
GO:0010569	regulation of double-strand break repair via homologous recombination	2.000091e-3
GO:0042069	regulation of catecholamine metabolic process	2.113841e-3
GO:0043153	entrainment of circadian clock by photoperiod	2.129050e-3
GO:0045136	development of secondary sexual characteristics	2.201757e-3
GO:0060216	definitive hemopoiesis	2.328670e-3
GO:0051026	chiasma assembly	2.329188e-3
GO:0006390	transcription from mitochondrial promoter	2.329188e-3
GO:0043148	mitotic spindle stabilization	2.358712e-3
GO:0006713	glucocorticoid catabolic process	2.358712e-3
GO:0018192	enzyme active site formation via L-cysteine persulfide	2.358712e-3
GO:0035566	regulation of metanephros size	2.399951e-3
GO:0097107	postsynaptic density assembly	2.439933e-3
GO:2000969	positive regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor activity	2.439933e-3
GO:0034421	post-translational protein acetylation	2.439933e-3
GO:0002221	pattern recognition receptor signaling pathway	2.471492e-3
GO:0009059	macromolecule biosynthetic process	2.491786e-3
GO:0032786	positive regulation of transcription elongation, DNA-dependent	2.628821e-3
GO:0016197	endosome transport	2.774607e-3
GO:0002030	inhibitory G-protein coupled receptor phosphorylation	2.817048e-3
GO:0000395	nuclear mRNA 5'-splice site recognition	2.817048e-3
GO:0001306	age-dependent response to oxidative stress	2.843758e-3
GO:0061205	paramesonephric duct development	2.858617e-3
GO:0019438	aromatic compound biosynthetic process	2.896403e-3
GO:0006325	chromatin organization	2.898989e-3
GO:0070192	chromosome organization involved in meiosis	3.008127e-3
GO:0040020	regulation of meiosis	3.039967e-3
GO:0006401	RNA catabolic process	3.047846e-3
GO:0001675	acrosome assembly	3.057706e-3
GO:0060136	embryonic process involved in female pregnancy	3.133343e-3
GO:0007288	sperm axoneme assembly	3.159016e-3
GO:0035865	cellular response to potassium ion	3.171535e-3
GO:0090212	negative regulation of establishment of blood-brain barrier	3.171535e-3
GO:0034651	cortisol biosynthetic process	3.171535e-3
GO:0060816	random inactivation of X chromosome	3.171535e-3
GO:0032621	interleukin-18 production	3.171535e-3
GO:0015969	guanosine tetraphosphate metabolic process	3.171535e-3
GO:0019047	provirus integration	3.171535e-3
GO:0032383	regulation of intracellular cholesterol transport	3.171535e-3
GO:0006298	mismatch repair	3.180299e-3
GO:0072205	metanephric collecting duct development	3.254980e-3
GO:0010891	negative regulation of sequestering of triglyceride	3.254980e-3
GO:0034243	regulation of transcription elongation from RNA polymerase II promoter	3.254980e-3
GO:0009650	UV protection	3.295839e-3
GO:0035246	peptidyl-arginine N-methylation	3.319287e-3
GO:0044249	cellular biosynthetic process	3.322050e-3
GO:0006449	regulation of translational termination	3.415555e-3
GO:0070734	histone H3-K27 methylation	3.508256e-3
GO:0016577	histone demethylation	3.629203e-3
GO:0031398	positive regulation of protein ubiquitination	3.643503e-3
GO:0090140	regulation of mitochondrial fission	3.712003e-3
GO:0007181	transforming growth factor beta receptor complex assembly	3.712003e-3
GO:0048854	brain morphogenesis	3.722425e-3
GO:0051028	mRNA transport	3.732119e-3
GO:0051726	regulation of cell cycle	3.767838e-3
GO:0002475	antigen processing and presentation via MHC class Ib	3.900637e-3
GO:0051645	Golgi localization	4.012895e-3
GO:0035564	regulation of kidney size	4.067480e-3
GO:0045901	positive regulation of translational elongation	4.079288e-3
GO:0045905	positive regulation of translational termination	4.079288e-3
GO:0019230	proprioception	4.079288e-3
GO:0032509	endosome transport via multivesicular body sorting pathway	4.079288e-3
GO:0006452	translational frameshifting	4.079288e-3
GO:0051030	snRNA transport	4.097165e-3
GO:0015959	diadenosine polyphosphate metabolic process	4.097165e-3
GO:0046853	inositol or phosphatidylinositol phosphorylation	4.097165e-3
GO:0070060	'de novo' actin filament nucleation	4.110520e-3
GO:0014063	negative regulation of serotonin secretion	4.110520e-3
GO:0031047	gene silencing by RNA	4.142873e-3
GO:0045837	negative regulation of membrane potential	4.301566e-3
GO:0000466	maturation of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)	4.304758e-3
GO:0008207	C21-steroid hormone metabolic process	4.410890e-3
GO:0043687	post-translational protein modification	4.479951e-3
GO:0002758	innate immune response-activating signal transduction	4.481116e-3
GO:0021575	hindbrain morphogenesis	4.539343e-3
GO:0030035	microspike assembly	4.590030e-3
GO:0042989	sequestering of actin monomers	4.616405e-3
GO:0007051	spindle organization	4.789465e-3
GO:0050701	interleukin-1 secretion	4.820449e-3
GO:0045046	protein import into peroxisome membrane	4.832874e-3
GO:0072133	metanephric mesenchyme morphogenesis	4.832874e-3
GO:0032202	telomere assembly	4.832874e-3
GO:0021533	cell differentiation in hindbrain	4.875685e-3
GO:0042450	arginine biosynthetic process via ornithine	4.879721e-3
GO:0046079	dUMP catabolic process	4.879721e-3
GO:0019676	ammonia assimilation cycle	4.879721e-3
GO:0014878	response to electrical stimulus involved in regulation of muscle adaptation	4.879721e-3
GO:0033617	mitochondrial respiratory chain complex IV assembly	4.879721e-3
GO:0018394	peptidyl-lysine acetylation	4.913821e-3
GO:0046543	development of secondary female sexual characteristics	4.931348e-3
GO:0018216	peptidyl-arginine methylation	4.950954e-3
GO:0006573	valine metabolic process	4.950954e-3
GO:0090224	regulation of spindle organization	4.964576e-3
GO:0007283	spermatogenesis	5.005721e-3
GO:0072172	mesonephric tubule formation	5.023967e-3
GO:0014051	gamma-aminobutyric acid secretion	5.023967e-3
GO:0017015	regulation of transforming growth factor beta receptor signaling pathway	5.132848e-3
GO:0002739	regulation of cytokine secretion involved in immune response	5.257739e-3
GO:0008612	peptidyl-lysine modification to hypusine	5.280039e-3
GO:0072171	mesonephric tubule morphogenesis	5.500769e-3
GO:0051496	positive regulation of stress fiber assembly	5.510041e-3
GO:0007129	synapsis	5.523665e-3
GO:0060501	positive regulation of epithelial cell proliferation involved in lung morphogenesis	5.523665e-3
GO:0033136	serine phosphorylation of STAT3 protein	5.657657e-3
GO:0032510	endosome to lysosome transport via multivesicular body sorting pathway	5.657657e-3
GO:0000720	pyrimidine dimer repair by nucleotide-excision repair	5.657657e-3
GO:0008090	retrograde axon cargo transport	5.676419e-3
GO:0010724	regulation of definitive erythrocyte differentiation	5.678545e-3
GO:0051176	positive regulation of sulfur metabolic process	5.753267e-3
GO:0006398	histone mRNA 3'-end processing	5.753267e-3
GO:0043653	mitochondrial fragmentation involved in apoptosis	5.753267e-3
GO:0048505	regulation of timing of cell differentiation	5.849302e-3
GO:0071922	regulation of cohesin localization to chromatin	5.962625e-3
GO:0071044	histone mRNA catabolic process	5.987457e-3
GO:0006475	internal protein amino acid acetylation	6.062453e-3
GO:0002832	negative regulation of response to biotic stimulus	6.130339e-3
GO:0072367	regulation of lipid transport by regulation of transcription from RNA polymerase II promoter	6.149121e-3
GO:0072361	regulation of glycolysis by regulation of transcription from RNA polymerase II promoter	6.149121e-3
GO:0032612	interleukin-1 production	6.149121e-3
GO:0070370	cellular heat acclimation	6.221988e-3
GO:0071279	cellular response to cobalt ion	6.221988e-3
GO:0032802	low-density lipoprotein particle receptor catabolic process	6.221988e-3
GO:0010637	negative regulation of mitochondrial fusion	6.221988e-3
GO:0000448	cleavage in ITS2 between 5.8S rRNA and LSU-rRNA of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)	6.221988e-3
GO:0010838	positive regulation of keratinocyte proliferation	6.273344e-3
GO:0071286	cellular response to magnesium ion	6.291175e-3
GO:0072044	collecting duct development	6.339902e-3
GO:0071156	regulation of cell cycle arrest	6.467222e-3
GO:0051642	centrosome localization	6.467956e-3
GO:0035562	negative regulation of chromatin binding	6.501582e-3
GO:0006481	C-terminal protein methylation	6.501582e-3
GO:0006417	regulation of translation	6.703356e-3
GO:0060564	negative regulation of mitotic anaphase-promoting complex activity	6.935591e-3
GO:0043951	negative regulation of cAMP-mediated signaling	6.935591e-3
GO:0018283	iron incorporation into metallo-sulfur cluster	6.935591e-3
GO:0035082	axoneme assembly	6.983526e-3
GO:0040034	regulation of development, heterochronic	6.997393e-3
GO:0051081	nuclear envelope disassembly	7.006612e-3
GO:0021993	initiation of neural tube closure	7.006612e-3
GO:0035582	negative regulation of BMP signaling pathway by extracellular sequestering of BMP	7.174957e-3
GO:0045900	negative regulation of translational elongation	7.174957e-3
GO:0007066	female meiosis sister chromatid cohesion	7.174957e-3
GO:0000963	mitochondrial RNA processing	7.174957e-3
GO:0016191	synaptic vesicle uncoating	7.246209e-3
GO:0006043	glucosamine catabolic process	7.246209e-3
GO:0008208	C21-steroid hormone catabolic process	7.246209e-3
GO:0050658	RNA transport	7.311839e-3
GO:0000132	establishment of mitotic spindle orientation	7.421627e-3
GO:0016570	histone modification	7.446745e-3
GO:0001678	cellular glucose homeostasis	7.453701e-3
GO:0002224	toll-like receptor signaling pathway	7.506374e-3
GO:0051403	stress-activated MAPK cascade	7.554900e-3
GO:0046599	regulation of centriole replication	7.625487e-3
GO:0071539	protein localization to centrosome	7.641070e-3
GO:0033540	fatty acid beta-oxidation using acyl-CoA oxidase	7.641070e-3
GO:0015680	intracellular copper ion transport	7.641070e-3
GO:0002591	positive regulation of antigen processing and presentation of peptide antigen via MHC class I	7.641070e-3
GO:0035234	germ cell programmed cell death	7.758190e-3
GO:0014044	Schwann cell development	7.775807e-3
GO:0035247	peptidyl-arginine omega-N-methylation	7.801339e-3
GO:0016540	protein autoprocessing	7.801339e-3
GO:0003344	pericardium morphogenesis	7.801339e-3
GO:0051443	positive regulation of ubiquitin-protein ligase activity	7.871462e-3
GO:0044154	histone H3-K14 acetylation	7.923059e-3
GO:0006351	transcription, DNA-dependent	8.156008e-3
GO:0030970	retrograde protein transport, ER to cytosol	8.304113e-3
GO:0006450	regulation of translational fidelity	8.304113e-3
GO:0018393	internal peptidyl-lysine acetylation	8.451330e-3
GO:0048541	Peyer's patch development	8.521178e-3
GO:0034587	piRNA metabolic process	8.596477e-3
GO:0010987	negative regulation of high-density lipoprotein particle clearance	8.648519e-3
GO:0010897	negative regulation of triglyceride catabolic process	8.648519e-3
GO:0015937	coenzyme A biosynthetic process	8.872633e-3
GO:0034660	ncRNA metabolic process	8.899561e-3
GO:0048741	skeletal muscle fiber development	9.124249e-3
GO:0043353	enucleate erythrocyte differentiation	9.125307e-3
GO:0032007	negative regulation of TOR signaling cascade	9.125307e-3
GO:0035507	regulation of myosin-light-chain-phosphatase activity	9.150889e-3
GO:0042089	cytokine biosynthetic process	9.205634e-3
GO:0006403	RNA localization	9.268540e-3
GO:0060318	definitive erythrocyte differentiation	9.345519e-3
GO:0009950	dorsal/ventral axis specification	9.485423e-3
GO:0045764	positive regulation of cellular amino acid metabolic process	9.522173e-3
GO:0016569	covalent chromatin modification	9.589167e-3
GO:0000082	G1/S transition of mitotic cell cycle	9.609609e-3
GO:0001302	replicative cell aging	9.641590e-3
GO:0035584	calcium-mediated signaling using intracellular calcium source	9.681287e-3
GO:0010025	wax biosynthetic process	9.681287e-3
GO:0001833	inner cell mass cell proliferation	9.816455e-3
GO:0008542	visual learning	9.827645e-3
GO:0090141	positive regulation of mitochondrial fission	9.837435e-3
GO:0031508	centromeric heterochromatin formation	9.837435e-3
GO:0032774	RNA biosynthetic process	1.001312e-2
GO:0006396	RNA processing	1.010745e-2
GO:0044237	cellular metabolic process	1.078787e-2
GO:0043983	histone H4-K12 acetylation	1.094812e-2
GO:0010903	negative regulation of very-low-density lipoprotein particle remodeling	1.094812e-2
GO:0018105	peptidyl-serine phosphorylation	1.096401e-2
GO:0060164	regulation of timing of neuron differentiation	1.109916e-2
GO:0000226	microtubule cytoskeleton organization	1.125971e-2
GO:0034436	glycoprotein transport	1.145170e-2
GO:0010722	regulation of ferrochelatase activity	1.145170e-2
GO:0032353	negative regulation of hormone biosynthetic process	1.155412e-2
GO:0002218	activation of innate immune response	1.163511e-2
GO:2000049	positive regulation of cell-cell adhesion mediated by cadherin	1.177588e-2
GO:0060837	blood vessel endothelial cell differentiation	1.177588e-2
GO:0048007	antigen processing and presentation, exogenous lipid antigen via MHC class Ib	1.179302e-2
GO:0003050	regulation of systemic arterial blood pressure by atrial natriuretic peptide	1.179302e-2
GO:0043305	negative regulation of mast cell degranulation	1.179302e-2
GO:0060024	rhythmic synaptic transmission	1.181098e-2
GO:0090150	establishment of protein localization in membrane	1.197661e-2
GO:0002268	follicular dendritic cell differentiation	1.199145e-2
GO:0072364	regulation of cellular ketone metabolic process by regulation of transcription from RNA polymerase II promoter	1.205906e-2
GO:0006182	cGMP biosynthetic process	1.212462e-2
GO:0051321	meiotic cell cycle	1.218425e-2
GO:0021555	midbrain-hindbrain boundary morphogenesis	1.227748e-2
GO:0035826	rubidium ion transport	1.250086e-2
GO:0046293	formaldehyde biosynthetic process	1.250086e-2
GO:0035481	positive regulation of Notch signaling pathway involved in heart induction	1.250086e-2
GO:0034276	kynurenic acid biosynthetic process	1.250086e-2
GO:0034021	response to silicon dioxide	1.250086e-2
GO:0046604	positive regulation of mitotic centrosome separation	1.250086e-2
GO:0060975	cardioblast migration to the midline involved in heart field formation	1.250086e-2
GO:2000682	positive regulation of rubidium ion transport	1.250086e-2
GO:2000688	positive regulation of rubidium ion transmembrane transporter activity	1.250086e-2
GO:2000363	positive regulation of prostaglandin-E synthase activity	1.250086e-2
GO:0071608	macrophage inflammatory protein-1 alpha production	1.250086e-2
GO:0033274	response to vitamin B2	1.250086e-2
GO:0048773	erythrophore differentiation	1.250086e-2
GO:0034136	negative regulation of toll-like receptor 2 signaling pathway	1.250086e-2
GO:0003210	cardiac atrium formation	1.250086e-2
GO:0032701	negative regulation of interleukin-18 production	1.250086e-2
GO:0003069	vasodilation by acetylcholine involved in regulation of systemic arterial blood pressure	1.250086e-2
GO:0002534	cytokine production involved in inflammatory response	1.250086e-2
GO:0001315	age-dependent response to reactive oxygen species	1.250086e-2
GO:0001682	tRNA 5'-leader removal	1.250086e-2
GO:0003259	cardioblast anterior-lateral migration	1.250086e-2
GO:0003236	sinus venosus morphogenesis	1.250086e-2
GO:0006965	positive regulation of biosynthetic process of antibacterial peptides active against Gram-positive bacteria	1.250086e-2
GO:0021941	negative regulation of cerebellar granule cell precursor proliferation	1.250086e-2
GO:0032498	detection of muramyl dipeptide	1.250086e-2
GO:0016078	tRNA catabolic process	1.250086e-2
GO:0009159	deoxyribonucleoside monophosphate catabolic process	1.250086e-2
GO:0010390	histone monoubiquitination	1.255192e-2
GO:0003306	Wnt receptor signaling pathway involved in heart development	1.256019e-2
GO:0006119	oxidative phosphorylation	1.258383e-2
GO:0010824	regulation of centrosome duplication	1.289361e-2
GO:0072385	minus-end-directed organelle transport along microtubule	1.292343e-2
GO:0002489	antigen processing and presentation of endogenous peptide antigen via MHC class Ib via ER pathway, TAP-dependent	1.292343e-2
GO:0043134	regulation of hindgut contraction	1.292343e-2
GO:0040001	establishment of mitotic spindle localization	1.295029e-2
GO:0007501	mesodermal cell fate specification	1.305026e-2
GO:0030917	midbrain-hindbrain boundary development	1.315720e-2
GO:0070816	phosphorylation of RNA polymerase II C-terminal domain	1.318254e-2
GO:0048536	spleen development	1.327651e-2
GO:0042107	cytokine metabolic process	1.331346e-2
GO:0008211	glucocorticoid metabolic process	1.340212e-2
GO:2000779	regulation of double-strand break repair	1.349306e-2
GO:0060083	smooth muscle contraction involved in micturition	1.351997e-2
GO:0060005	vestibular reflex	1.351997e-2
GO:0050881	musculoskeletal movement	1.362119e-2
GO:0070625	zymogen granule exocytosis	1.370932e-2
GO:0090281	negative regulation of calcium ion import	1.370932e-2
GO:0071584	negative regulation of zinc ion import	1.370932e-2
GO:0048697	positive regulation of collateral sprouting in absence of injury	1.370932e-2
GO:0044314	protein K27-linked ubiquitination	1.370932e-2
GO:0051303	establishment of chromosome localization	1.389601e-2
GO:0009755	hormone-mediated signaling pathway	1.408343e-2
GO:0043517	positive regulation of DNA damage response, signal transduction by p53 class mediator	1.410890e-2
GO:0072179	nephric duct formation	1.421998e-2
GO:0046653	tetrahydrofolate metabolic process	1.421998e-2
GO:0045836	positive regulation of meiosis	1.424257e-2
GO:0071557	histone H3-K27 demethylation	1.429229e-2
GO:0035574	histone H4-K20 demethylation	1.429229e-2
GO:0006434	seryl-tRNA aminoacylation	1.429229e-2
GO:0006498	N-terminal protein lipidation	1.429229e-2
GO:0060397	JAK-STAT cascade involved in growth hormone signaling pathway	1.434711e-2
GO:2000171	negative regulation of dendrite development	1.466953e-2
GO:0002331	pre-B cell allelic exclusion	1.466953e-2
GO:0033007	negative regulation of mast cell activation involved in immune response	1.466953e-2
GO:0006414	translational elongation	1.479853e-2
GO:0072307	regulation of metanephric nephron tubule epithelial cell differentiation	1.500587e-2
GO:0030325	adrenal gland development	1.504905e-2
GO:0010888	negative regulation of lipid storage	1.599953e-2
GO:0072189	ureter development	1.607589e-2
GO:0060686	negative regulation of prostatic bud formation	1.609580e-2
GO:0006122	mitochondrial electron transport, ubiquinol to cytochrome c	1.626741e-2
GO:0031848	protection from non-homologous end joining at telomere	1.626741e-2
GO:0050872	white fat cell differentiation	1.670216e-2
GO:0016567	protein ubiquitination	1.670341e-2
GO:0016486	peptide hormone processing	1.697797e-2
GO:0045190	isotype switching	1.716749e-2
GO:0072362	regulation of glycolysis by negative regulation of transcription from RNA polymerase II promoter	1.717189e-2
GO:0072368	regulation of lipid transport by negative regulation of transcription from RNA polymerase II promoter	1.717189e-2
GO:0034699	response to luteinizing hormone stimulus	1.717189e-2
GO:0000492	box C/D snoRNP assembly	1.717189e-2
GO:0060598	dichotomous subdivision of terminal units involved in mammary gland duct morphogenesis	1.717189e-2
GO:0019348	dolichol metabolic process	1.755270e-2
GO:0033522	histone H2A ubiquitination	1.764019e-2
GO:0010822	positive regulation of mitochondrion organization	1.792640e-2
GO:0021819	layer formation in cerebral cortex	1.824761e-2
GO:0046544	development of secondary male sexual characteristics	1.830934e-2
GO:0001887	selenium compound metabolic process	1.830934e-2
GO:0042424	catecholamine catabolic process	1.856881e-2
GO:0061033	secretion by lung epithelial cell involved in lung growth	1.866758e-2
GO:0046499	S-adenosylmethioninamine metabolic process	1.866758e-2
GO:0033026	negative regulation of mast cell apoptosis	1.866758e-2
GO:0070198	protein localization to chromosome, telomeric region	1.872836e-2
GO:0060067	cervix development	1.872836e-2
GO:0045646	regulation of erythrocyte differentiation	1.879651e-2
GO:0000184	nuclear-transcribed mRNA catabolic process, nonsense-mediated decay	1.887419e-2
GO:0051964	negative regulation of synapse assembly	1.903889e-2
GO:0006600	creatine metabolic process	1.903889e-2
GO:0000075	cell cycle checkpoint	1.913880e-2
GO:0072182	regulation of nephron tubule epithelial cell differentiation	1.915780e-2
GO:0032467	positive regulation of cytokinesis	1.924073e-2