Novel motif:161

name:	motif161_CGGCTTGATT

Association to promoter expression in human samples<b>Summary:</b>Significance of the correlation with CAGE expression, human <br><b>Analyst:</b> Michiel de Hoon<br><br>link to source dataset <br>data

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Association to promoter expression in mouse samples <b>Summary:</b>Significance of the correlation with CAGE expression, mouse <br><b>Analyst:</b> Michiel de Hoon<br><br>link to source dataset <br>data

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GREAT analysis results for human <b>Summary:</b>Genomic Enrichment of Annotations Tool (GREAT, Nat Biotechnol. 2010 May;28(5):495-501) is used to identify, both in human and in mouse, the gene ontology terms of biological processes enriched given the predicted TFBSs, and evaluated the overlap in the top-500 gene ontology terms between human and mouse. For each novel motif, the P value for the overlap was then evaluated by calculating its relative rank with respect to this background distribution.<br>Analyst: Michiel de Hoon<br><br>link to source dataset <br>data

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GO ID	GO Term	p-value
GO:0042985	negative regulation of amyloid precursor protein biosynthetic process	6.224177e-10
GO:0090086	negative regulation of protein deubiquitination	4.404815e-9
GO:0009084	glutamine family amino acid biosynthetic process	7.799066e-9
GO:0010983	positive regulation of high-density lipoprotein particle clearance	1.107606e-8
GO:0007208	activation of phospholipase C activity by serotonin receptor signaling pathway	1.107606e-8
GO:0090085	regulation of protein deubiquitination	1.609274e-8
GO:0030433	ER-associated protein catabolic process	2.082875e-8
GO:0051382	kinetochore assembly	2.711195e-8
GO:0051383	kinetochore organization	5.515273e-8
GO:0031116	positive regulation of microtubule polymerization	6.313938e-8
GO:0021570	rhombomere 4 development	7.108751e-8
GO:0010561	negative regulation of glycoprotein biosynthetic process	1.211038e-7
GO:0014908	myotube differentiation involved in skeletal muscle regeneration	1.387916e-7
GO:0021569	rhombomere 3 development	1.460671e-7
GO:0043316	cytotoxic T cell degranulation	1.467622e-7
GO:0010986	positive regulation of lipoprotein particle clearance	1.467622e-7
GO:0034976	response to endoplasmic reticulum stress	2.212298e-7
GO:0070145	mitochondrial asparaginyl-tRNA aminoacylation	2.385666e-7
GO:0021599	abducens nerve formation	2.385666e-7
GO:0007634	optokinetic behavior	2.385666e-7
GO:0002115	store-operated calcium entry	4.488657e-7
GO:0051915	induction of synaptic plasticity by chemical substance	6.678267e-7
GO:0050668	positive regulation of homocysteine metabolic process	6.684106e-7
GO:0045963	negative regulation of dopamine metabolic process	6.684106e-7
GO:0061384	heart trabecular morphogenesis	6.820397e-7
GO:0034699	response to luteinizing hormone stimulus	1.048196e-6
GO:0050652	dermatan sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process	1.048196e-6
GO:0070389	chaperone cofactor-dependent protein refolding	1.130212e-6
GO:0006986	response to unfolded protein	1.387555e-6
GO:0021612	facial nerve structural organization	1.431352e-6
GO:0031112	positive regulation of microtubule polymerization or depolymerization	1.601103e-6
GO:0042026	protein refolding	1.656093e-6
GO:0022600	digestive system process	1.786411e-6
GO:0034637	cellular carbohydrate biosynthetic process	1.795289e-6
GO:0034508	centromere complex assembly	2.068668e-6
GO:0010459	negative regulation of heart rate	2.239845e-6
GO:0050666	regulation of homocysteine metabolic process	2.334316e-6
GO:0030101	natural killer cell activation	2.406885e-6
GO:0002285	lymphocyte activation involved in immune response	3.171872e-6
GO:0070885	negative regulation of calcineurin-NFAT signaling pathway	3.427226e-6
GO:0043320	natural killer cell degranulation	4.162023e-6
GO:0001578	microtubule bundle formation	5.237774e-6
GO:0021602	cranial nerve morphogenesis	6.017855e-6
GO:0090189	regulation of branching involved in ureteric bud morphogenesis	6.179545e-6
GO:0060347	heart trabecula formation	6.349992e-6
GO:0090183	regulation of kidney development	6.677529e-6
GO:0051967	negative regulation of synaptic transmission, glutamatergic	7.309200e-6
GO:0048676	axon extension involved in development	7.351774e-6
GO:0090281	negative regulation of calcium ion import	7.564613e-6
GO:0071584	negative regulation of zinc ion import	7.564613e-6
GO:0007586	digestion	8.041201e-6
GO:0042267	natural killer cell mediated cytotoxicity	9.319660e-6
GO:0010734	negative regulation of protein glutathionylation	9.761260e-6
GO:0002689	negative regulation of leukocyte chemotaxis	9.844655e-6
GO:0051310	metaphase plate congression	1.083290e-5
GO:0033240	positive regulation of cellular amine metabolic process	1.097966e-5
GO:0032203	telomere formation via telomerase	1.103480e-5
GO:0048532	anatomical structure arrangement	1.223457e-5
GO:0032230	positive regulation of synaptic transmission, GABAergic	1.426828e-5
GO:0060876	semicircular canal formation	1.500801e-5
GO:0034766	negative regulation of ion transmembrane transport	1.697557e-5
GO:0035966	response to topologically incorrect protein	1.891767e-5
GO:0006797	polyphosphate metabolic process	1.915958e-5
GO:0021546	rhombomere development	1.991344e-5
GO:0048639	positive regulation of developmental growth	2.037916e-5
GO:0010982	regulation of high-density lipoprotein particle clearance	2.075835e-5
GO:0007518	myoblast cell fate determination	2.466523e-5
GO:0032237	activation of store-operated calcium channel activity	2.512381e-5
GO:0045116	protein neddylation	2.549812e-5
GO:0042984	regulation of amyloid precursor protein biosynthetic process	2.827345e-5
GO:0031113	regulation of microtubule polymerization	2.986889e-5
GO:0021610	facial nerve morphogenesis	2.992379e-5
GO:0021603	cranial nerve formation	3.046078e-5
GO:0061162	establishment of monopolar cell polarity	3.181376e-5
GO:0045927	positive regulation of growth	3.183199e-5
GO:0060676	ureteric bud formation	3.242733e-5
GO:0060300	regulation of cytokine activity	3.642847e-5
GO:0048793	pronephros development	3.921833e-5
GO:0042797	tRNA transcription from RNA polymerase III promoter	4.085535e-5
GO:0042791	5S class rRNA transcription from RNA polymerase III type 1 promoter	4.085535e-5
GO:0071585	detoxification of cadmium ion	4.568540e-5
GO:0021561	facial nerve development	4.924189e-5
GO:0051654	establishment of mitochondrion localization	5.321877e-5
GO:0000236	mitotic prometaphase	5.322265e-5
GO:0030509	BMP signaling pathway	5.429249e-5
GO:0006537	glutamate biosynthetic process	5.695615e-5
GO:0090190	positive regulation of branching involved in ureteric bud morphogenesis	6.327810e-5
GO:0002312	B cell activation involved in immune response	7.258731e-5
GO:0006421	asparaginyl-tRNA aminoacylation	7.775831e-5
GO:0090084	negative regulation of inclusion body assembly	7.809780e-5
GO:0048144	fibroblast proliferation	8.504764e-5
GO:0072205	metanephric collecting duct development	8.905504e-5
GO:0001909	leukocyte mediated cytotoxicity	9.033504e-5
GO:0033120	positive regulation of RNA splicing	9.114967e-5
GO:0030968	endoplasmic reticulum unfolded protein response	9.642439e-5
GO:0060409	positive regulation of acetylcholine metabolic process	1.023565e-4
GO:0009304	tRNA transcription	1.054696e-4
GO:0002316	follicular B cell differentiation	1.054696e-4
GO:0021604	cranial nerve structural organization	1.103780e-4
GO:0006542	glutamine biosynthetic process	1.162105e-4
GO:2000353	positive regulation of endothelial cell apoptosis	1.187115e-4
GO:0016051	carbohydrate biosynthetic process	1.190829e-4
GO:0009236	cobalamin biosynthetic process	1.222616e-4
GO:0045822	negative regulation of heart contraction	1.279977e-4
GO:0051973	positive regulation of telomerase activity	1.312573e-4
GO:0047497	mitochondrion transport along microtubule	1.349536e-4
GO:0006268	DNA unwinding involved in replication	1.404500e-4
GO:0021754	facial nucleus development	1.453214e-4
GO:0060301	positive regulation of cytokine activity	1.546427e-4
GO:0046184	aldehyde biosynthetic process	1.546427e-4
GO:0006538	glutamate catabolic process	1.664979e-4
GO:0006457	protein folding	1.883894e-4
GO:0001832	blastocyst growth	1.927128e-4
GO:0033692	cellular polysaccharide biosynthetic process	1.954768e-4
GO:0072215	regulation of metanephros development	1.998595e-4
GO:0072060	outer medullary collecting duct development	2.000195e-4
GO:0072061	inner medullary collecting duct development	2.000195e-4
GO:0070127	tRNA aminoacylation for mitochondrial protein translation	2.000195e-4
GO:0016332	establishment or maintenance of polarity of embryonic epithelium	2.000195e-4
GO:0072110	glomerular mesangial cell proliferation	2.048531e-4
GO:0002456	T cell mediated immunity	2.207453e-4
GO:0048754	branching morphogenesis of a tube	2.248334e-4
GO:0002366	leukocyte activation involved in immune response	2.312848e-4
GO:0060318	definitive erythrocyte differentiation	2.328483e-4
GO:0043501	skeletal muscle adaptation	2.404243e-4
GO:0034088	maintenance of mitotic sister chromatid cohesion	2.501701e-4
GO:0009620	response to fungus	2.593368e-4
GO:0048638	regulation of developmental growth	2.595853e-4
GO:0090083	regulation of inclusion body assembly	2.653262e-4
GO:0072303	positive regulation of glomerular metanephric mesangial cell proliferation	2.697708e-4
GO:0035115	embryonic forelimb morphogenesis	2.716181e-4
GO:0046007	negative regulation of activated T cell proliferation	2.757253e-4
GO:0032202	telomere assembly	2.855563e-4
GO:0032660	regulation of interleukin-17 production	3.221671e-4
GO:0045907	positive regulation of vasoconstriction	3.407746e-4
GO:0072126	positive regulation of glomerular mesangial cell proliferation	3.552534e-4
GO:0046541	saliva secretion	3.552534e-4
GO:0071506	cellular response to mycophenolic acid	3.552534e-4
GO:0051156	glucose 6-phosphate metabolic process	3.654638e-4
GO:0007522	visceral muscle development	3.701400e-4
GO:0070925	organelle assembly	3.834859e-4
GO:0035136	forelimb morphogenesis	3.869393e-4
GO:0030308	negative regulation of cell growth	3.888864e-4
GO:0045764	positive regulation of cellular amino acid metabolic process	3.940656e-4
GO:0035117	embryonic arm morphogenesis	3.940656e-4
GO:0014888	striated muscle adaptation	3.948389e-4
GO:0000733	DNA strand renaturation	4.086744e-4
GO:0061387	regulation of extent of cell growth	4.288638e-4
GO:0032958	inositol phosphate biosynthetic process	4.319817e-4
GO:0043266	regulation of potassium ion transport	4.321934e-4
GO:0050849	negative regulation of calcium-mediated signaling	4.359062e-4
GO:0060074	synapse maturation	4.402461e-4
GO:0045773	positive regulation of axon extension	4.521407e-4
GO:0033239	negative regulation of cellular amine metabolic process	4.656207e-4
GO:0032224	positive regulation of synaptic transmission, cholinergic	4.656207e-4
GO:0061084	negative regulation of protein refolding	4.776372e-4
GO:0072109	glomerular mesangium development	4.776372e-4
GO:0060444	branching involved in mammary gland duct morphogenesis	4.989441e-4
GO:0030516	regulation of axon extension	5.090989e-4
GO:0060356	leucine import	5.115825e-4
GO:0007059	chromosome segregation	5.145444e-4
GO:0031110	regulation of microtubule polymerization or depolymerization	5.211846e-4
GO:0072044	collecting duct development	5.212449e-4
GO:0000085	G2 phase of mitotic cell cycle	5.270117e-4
GO:0003337	mesenchymal to epithelial transition involved in metanephros morphogenesis	5.557213e-4
GO:0034441	plasma lipoprotein particle oxidation	6.021531e-4
GO:0032236	positive regulation of calcium ion transport via store-operated calcium channel activity	6.048628e-4
GO:0043484	regulation of RNA splicing	6.049534e-4
GO:0007064	mitotic sister chromatid cohesion	6.067609e-4
GO:0010984	regulation of lipoprotein particle clearance	6.143754e-4
GO:0060629	regulation of homologous chromosome segregation	6.495199e-4
GO:0051598	meiotic recombination checkpoint	6.495199e-4
GO:0050703	interleukin-1 alpha secretion	6.948275e-4
GO:0002729	positive regulation of natural killer cell cytokine production	6.948275e-4
GO:0061099	negative regulation of protein tyrosine kinase activity	6.985497e-4
GO:0002313	mature B cell differentiation involved in immune response	7.075056e-4
GO:0009205	purine ribonucleoside triphosphate metabolic process	7.152771e-4
GO:0060666	dichotomous subdivision of terminal units involved in salivary gland branching	7.396185e-4
GO:0035967	cellular response to topologically incorrect protein	7.403598e-4
GO:0002026	regulation of the force of heart contraction	7.403598e-4
GO:0045348	positive regulation of MHC class II biosynthetic process	7.545146e-4
GO:0009199	ribonucleoside triphosphate metabolic process	7.629213e-4
GO:0021545	cranial nerve development	7.700435e-4
GO:0046364	monosaccharide biosynthetic process	7.834690e-4
GO:0030307	positive regulation of cell growth	7.918224e-4
GO:0043415	positive regulation of skeletal muscle tissue regeneration	8.186859e-4
GO:0070884	regulation of calcineurin-NFAT signaling pathway	8.495929e-4
GO:0043268	positive regulation of potassium ion transport	9.177952e-4
GO:0030277	maintenance of gastrointestinal epithelium	9.214181e-4
GO:0046929	negative regulation of neurotransmitter secretion	9.464532e-4
GO:0019319	hexose biosynthetic process	9.564517e-4
GO:0002769	natural killer cell inhibitory signaling pathway	9.573565e-4
GO:0051775	response to redox state	9.903122e-4
GO:0021783	preganglionic parasympathetic nervous system development	1.000752e-3
GO:0014012	peripheral nervous system axon regeneration	1.000752e-3
GO:0061138	morphogenesis of a branching epithelium	1.003053e-3
GO:0048675	axon extension	1.015292e-3
GO:0060482	lobar bronchus development	1.043467e-3
GO:0060600	dichotomous subdivision of an epithelial terminal unit	1.048374e-3
GO:2000286	receptor internalization involved in canonical Wnt receptor signaling pathway	1.056658e-3
GO:0071398	cellular response to fatty acid	1.061366e-3
GO:0046884	follicle-stimulating hormone secretion	1.088457e-3
GO:0032275	luteinizing hormone secretion	1.088457e-3
GO:0072668	tubulin complex biogenesis	1.102218e-3
GO:0002027	regulation of heart rate	1.102231e-3
GO:0072283	metanephric renal vesicle morphogenesis	1.190069e-3
GO:0045660	positive regulation of neutrophil differentiation	1.245647e-3
GO:0009144	purine nucleoside triphosphate metabolic process	1.260671e-3
GO:0006084	acetyl-CoA metabolic process	1.264729e-3
GO:0033119	negative regulation of RNA splicing	1.287045e-3
GO:0050653	chondroitin sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process	1.301329e-3
GO:0060628	regulation of ER to Golgi vesicle-mediated transport	1.343925e-3
GO:0070574	cadmium ion transmembrane transport	1.347635e-3
GO:0072087	renal vesicle development	1.362768e-3
GO:0060992	response to fungicide	1.371104e-3
GO:0042532	negative regulation of tyrosine phosphorylation of STAT protein	1.391667e-3
GO:0043950	positive regulation of cAMP-mediated signaling	1.418985e-3
GO:0007495	visceral mesoderm-endoderm interaction involved in midgut development	1.418985e-3
GO:0001833	inner cell mass cell proliferation	1.423844e-3
GO:0002238	response to molecule of fungal origin	1.424584e-3
GO:0051646	mitochondrion localization	1.431340e-3
GO:0001696	gastric acid secretion	1.463071e-3
GO:0007026	negative regulation of microtubule depolymerization	1.514371e-3
GO:0060560	developmental growth involved in morphogenesis	1.540772e-3
GO:0035409	histone H3-Y41 phosphorylation	1.542080e-3
GO:0008636	activation of caspase activity by protein phosphorylation	1.542080e-3
GO:0014732	skeletal muscle atrophy	1.586069e-3
GO:0001824	blastocyst development	1.649469e-3
GO:0050922	negative regulation of chemotaxis	1.657656e-3
GO:0021636	trigeminal nerve morphogenesis	1.716961e-3
GO:2000134	negative regulation of G1/S transition of mitotic cell cycle	1.750066e-3
GO:0010959	regulation of metal ion transport	1.925513e-3
GO:0072077	renal vesicle morphogenesis	1.931496e-3
GO:0031114	regulation of microtubule depolymerization	1.985736e-3
GO:0003338	metanephros morphogenesis	2.001722e-3
GO:0048554	positive regulation of metalloenzyme activity	2.003787e-3
GO:0018027	peptidyl-lysine dimethylation	2.003787e-3
GO:0032024	positive regulation of insulin secretion	2.009838e-3
GO:0061077	chaperone-mediated protein folding	2.034370e-3
GO:0090277	positive regulation of peptide hormone secretion	2.078688e-3
GO:0048739	cardiac muscle fiber development	2.079263e-3
GO:0019408	dolichol biosynthetic process	2.158600e-3
GO:0071481	cellular response to X-ray	2.160414e-3
GO:0048305	immunoglobulin secretion	2.160414e-3
GO:0010388	cullin deneddylation	2.298181e-3
GO:0007023	post-chaperonin tubulin folding pathway	2.298719e-3
GO:0007050	cell cycle arrest	2.324931e-3
GO:0071526	semaphorin-plexin signaling pathway	2.348011e-3
GO:0045084	positive regulation of interleukin-12 biosynthetic process	2.360413e-3
GO:0072307	regulation of metanephric nephron tubule epithelial cell differentiation	2.364663e-3
GO:0050746	regulation of lipoprotein metabolic process	2.364663e-3
GO:0010477	response to sulfur dioxide	2.379266e-3
GO:0002457	T cell antigen processing and presentation	2.379266e-3
GO:0002793	positive regulation of peptide secretion	2.394095e-3
GO:0009150	purine ribonucleotide metabolic process	2.402939e-3
GO:0061383	trabecula morphogenesis	2.440934e-3
GO:0009404	toxin metabolic process	2.459984e-3
GO:0009154	purine ribonucleotide catabolic process	2.493923e-3
GO:0006264	mitochondrial DNA replication	2.509112e-3
GO:0045786	negative regulation of cell cycle	2.590712e-3
GO:0051303	establishment of chromosome localization	2.641274e-3
GO:0055009	atrial cardiac muscle tissue morphogenesis	2.644815e-3
GO:0007214	gamma-aminobutyric acid signaling pathway	2.644815e-3
GO:0009141	nucleoside triphosphate metabolic process	2.665136e-3
GO:0061010	gall bladder development	2.733633e-3
GO:0035261	external genitalia morphogenesis	2.733633e-3
GO:0007181	transforming growth factor beta receptor complex assembly	2.733633e-3
GO:0030259	lipid glycosylation	2.743285e-3
GO:0055091	phospholipid homeostasis	2.751506e-3
GO:0009261	ribonucleotide catabolic process	2.818746e-3
GO:0002121	inter-male aggressive behavior	2.853466e-3
GO:0017085	response to insecticide	2.868940e-3
GO:0046887	positive regulation of hormone secretion	2.888005e-3
GO:0001834	trophectodermal cell proliferation	2.926723e-3
GO:0032831	positive regulation of CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation	2.926723e-3
GO:0007402	ganglion mother cell fate determination	2.926723e-3
GO:0048486	parasympathetic nervous system development	2.941705e-3
GO:0048012	hepatocyte growth factor receptor signaling pathway	3.019161e-3
GO:0002335	mature B cell differentiation	3.046531e-3
GO:0043615	astrocyte cell migration	3.090021e-3
GO:0000462	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)	3.090021e-3
GO:2000602	regulation of interphase of mitotic cell cycle	3.160842e-3
GO:0050732	negative regulation of peptidyl-tyrosine phosphorylation	3.206878e-3
GO:0010159	specification of organ position	3.227377e-3
GO:0090279	regulation of calcium ion import	3.276346e-3
GO:0009207	purine ribonucleoside triphosphate catabolic process	3.293509e-3
GO:0043508	negative regulation of JUN kinase activity	3.303577e-3
GO:0002924	negative regulation of humoral immune response mediated by circulating immunoglobulin	3.307817e-3
GO:2000045	regulation of G1/S transition of mitotic cell cycle	3.335732e-3
GO:0007217	tachykinin receptor signaling pathway	3.386953e-3
GO:0009636	response to toxin	3.423020e-3
GO:0009313	oligosaccharide catabolic process	3.472680e-3
GO:0048588	developmental cell growth	3.636248e-3
GO:0042632	cholesterol homeostasis	3.643807e-3
GO:0009146	purine nucleoside triphosphate catabolic process	3.669287e-3
GO:0061038	uterus morphogenesis	3.678001e-3
GO:0070509	calcium ion import	3.778306e-3
GO:0050804	regulation of synaptic transmission	3.783891e-3
GO:0060904	regulation of protein folding in endoplasmic reticulum	3.801771e-3
GO:0070060	'de novo' actin filament nucleation	3.801771e-3
GO:0039020	pronephric nephron tubule development	3.801771e-3
GO:0035565	regulation of pronephros size	3.801771e-3
GO:0021589	cerebellum structural organization	3.801771e-3
GO:0045591	positive regulation of regulatory T cell differentiation	3.863052e-3
GO:0070914	UV-damage excision repair	3.863052e-3
GO:0051177	meiotic sister chromatid cohesion	3.863052e-3
GO:0043060	meiotic metaphase I plate congression	3.863052e-3
GO:0019242	methylglyoxal biosynthetic process	3.863052e-3
GO:0032228	regulation of synaptic transmission, GABAergic	3.973909e-3
GO:0072301	regulation of metanephric glomerular mesangial cell proliferation	4.088567e-3
GO:0048702	embryonic neurocranium morphogenesis	4.088567e-3
GO:0045019	negative regulation of nitric oxide biosynthetic process	4.143661e-3
GO:0031915	positive regulation of synaptic plasticity	4.272850e-3
GO:0071985	multivesicular body sorting pathway	4.351991e-3
GO:0060770	negative regulation of epithelial cell proliferation involved in prostate gland development	4.351991e-3
GO:0018022	peptidyl-lysine methylation	4.351991e-3
GO:0060399	positive regulation of growth hormone receptor signaling pathway	4.399288e-3
GO:0016480	negative regulation of transcription from RNA polymerase III promoter	4.399288e-3
GO:0030510	regulation of BMP signaling pathway	4.454807e-3
GO:0009143	nucleoside triphosphate catabolic process	4.669113e-3
GO:0051036	regulation of endosome size	4.676049e-3
GO:0046426	negative regulation of JAK-STAT cascade	4.959565e-3
GO:0071459	protein localization to chromosome, centromeric region	4.983462e-3
GO:0033590	response to cobalamin	4.983462e-3
GO:0006117	acetaldehyde metabolic process	4.983462e-3
GO:0030187	melatonin biosynthetic process	4.983462e-3
GO:0009438	methylglyoxal metabolic process	4.983462e-3
GO:0032042	mitochondrial DNA metabolic process	5.108695e-3
GO:0007130	synaptonemal complex assembly	5.113925e-3
GO:0033031	positive regulation of neutrophil apoptosis	5.185617e-3
GO:0070165	positive regulation of adiponectin secretion	5.185617e-3
GO:0035767	endothelial cell chemotaxis	5.388032e-3
GO:0006094	gluconeogenesis	5.489701e-3
GO:0007210	serotonin receptor signaling pathway	5.543773e-3
GO:0030540	female genitalia development	5.543773e-3
GO:0050832	defense response to fungus	5.549506e-3
GO:0042351	'de novo' GDP-L-fucose biosynthetic process	5.595230e-3
GO:0009051	pentose-phosphate shunt, oxidative branch	5.617423e-3
GO:0032513	negative regulation of protein phosphatase type 2B activity	5.649043e-3
GO:0060762	regulation of branching involved in mammary gland duct morphogenesis	5.723729e-3
GO:0051260	protein homooligomerization	5.764666e-3
GO:0032402	melanosome transport	5.868732e-3
GO:0072054	renal outer medulla development	5.885036e-3
GO:0072053	renal inner medulla development	5.885036e-3
GO:0042518	negative regulation of tyrosine phosphorylation of Stat3 protein	5.885036e-3
GO:0021571	rhombomere 5 development	5.885036e-3
GO:0009259	ribonucleotide metabolic process	5.903075e-3
GO:0006184	GTP catabolic process	5.970541e-3
GO:0006984	ER-nucleus signaling pathway	5.988837e-3
GO:0032959	inositol trisphosphate biosynthetic process	6.047924e-3
GO:0071479	cellular response to ionizing radiation	6.100647e-3
GO:0002686	negative regulation of leukocyte migration	6.139302e-3
GO:0019062	virion attachment to host cell surface receptor	6.182703e-3
GO:0001906	cell killing	6.207060e-3
GO:0051972	regulation of telomerase activity	6.211474e-3
GO:0043242	negative regulation of protein complex disassembly	6.260064e-3
GO:0001558	regulation of cell growth	6.307360e-3
GO:0072012	glomerulus vasculature development	6.447525e-3
GO:0033002	muscle cell proliferation	6.578372e-3
GO:0032689	negative regulation of interferon-gamma production	6.632181e-3
GO:0045658	regulation of neutrophil differentiation	6.634885e-3
GO:0001732	formation of translation initiation complex	6.634885e-3
GO:0043299	leukocyte degranulation	6.673615e-3
GO:0030149	sphingolipid catabolic process	6.673615e-3
GO:0006383	transcription from RNA polymerase III promoter	6.730374e-3
GO:0015805	S-adenosylmethionine transport	6.741572e-3
GO:0002765	immune response-inhibiting signal transduction	6.741572e-3
GO:0031103	axon regeneration	6.780643e-3
GO:0072108	positive regulation of mesenchymal to epithelial transition involved in metanephros morphogenesis	6.913707e-3
GO:0006195	purine nucleotide catabolic process	6.957829e-3
GO:0050860	negative regulation of T cell receptor signaling pathway	7.018537e-3
GO:0007028	cytoplasm organization	7.041834e-3
GO:0055017	cardiac muscle tissue growth	7.198026e-3
GO:0060535	trachea cartilage morphogenesis	7.205846e-3
GO:0072089	stem cell proliferation	7.205846e-3
GO:0033687	osteoblast proliferation	7.205846e-3
GO:0006561	proline biosynthetic process	7.205846e-3
GO:0031111	negative regulation of microtubule polymerization or depolymerization	7.313963e-3
GO:0090192	regulation of glomerulus development	7.530590e-3
GO:0032273	positive regulation of protein polymerization	7.550480e-3
GO:0048025	negative regulation of nuclear mRNA splicing, via spliceosome	7.650990e-3
GO:0051102	DNA ligation involved in DNA recombination	7.658296e-3
GO:0006425	glutaminyl-tRNA aminoacylation	7.658296e-3
GO:0071243	cellular response to arsenic-containing substance	7.690159e-3
GO:0009395	phospholipid catabolic process	7.762367e-3
GO:0000080	G1 phase of mitotic cell cycle	7.765959e-3
GO:0048024	regulation of nuclear mRNA splicing, via spliceosome	7.935321e-3
GO:0070358	actin polymerization-dependent cell motility	7.950921e-3
GO:0060343	trabecula formation	7.995030e-3
GO:0003229	ventricular cardiac muscle tissue development	8.015681e-3
GO:0032792	negative regulation of CREB transcription factor activity	8.024581e-3
GO:0003339	regulation of mesenchymal to epithelial transition involved in metanephros morphogenesis	8.388084e-3
GO:0035860	glial cell-derived neurotrophic factor receptor signaling pathway	8.436896e-3
GO:0003416	endochondral bone growth	8.563612e-3
GO:0060419	heart growth	8.598315e-3
GO:0043933	macromolecular complex subunit organization	8.627311e-3
GO:0043623	cellular protein complex assembly	8.688317e-3
GO:0043697	cell dedifferentiation	8.728357e-3
GO:2000773	negative regulation of cellular senescence	8.728357e-3
GO:0046039	GTP metabolic process	8.822507e-3
GO:0048483	autonomic nervous system development	8.849520e-3
GO:0006982	response to lipid hydroperoxide	9.090396e-3
GO:0061180	mammary gland epithelium development	9.185093e-3
GO:0055010	ventricular cardiac muscle tissue morphogenesis	9.195943e-3
GO:0046320	regulation of fatty acid oxidation	9.247121e-3
GO:0072181	mesonephric duct formation	9.279737e-3
GO:0042138	meiotic DNA double-strand break formation	9.279737e-3
GO:0034314	Arp2/3 complex-mediated actin nucleation	9.279737e-3
GO:0033313	meiotic cell cycle checkpoint	9.279737e-3
GO:0070271	protein complex biogenesis	9.353283e-3
GO:0046466	membrane lipid catabolic process	9.366574e-3
GO:0006646	phosphatidylethanolamine biosynthetic process	9.575541e-3
GO:0032383	regulation of intracellular cholesterol transport	9.594235e-3
GO:0051904	pigment granule transport	9.743341e-3
GO:0045750	positive regulation of S phase of mitotic cell cycle	9.810622e-3
GO:0072384	organelle transport along microtubule	9.879506e-3
GO:0048535	lymph node development	9.931126e-3
GO:0033233	regulation of protein sumoylation	1.006772e-2
GO:0072111	cell proliferation involved in kidney development	1.020061e-2
GO:0045926	negative regulation of growth	1.033829e-2
GO:0009166	nucleotide catabolic process	1.036707e-2
GO:0050687	negative regulation of defense response to virus	1.046819e-2
GO:0032222	regulation of synaptic transmission, cholinergic	1.046819e-2
GO:0032793	positive regulation of CREB transcription factor activity	1.047409e-2
GO:0072355	histone H3-T3 phosphorylation	1.055636e-2
GO:0015706	nitrate transport	1.055636e-2
GO:0010571	positive regulation of DNA replication involved in S phase	1.055636e-2
GO:0035880	embryonic nail plate morphogenesis	1.056209e-2
GO:0002291	T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell	1.073028e-2
GO:0060688	regulation of morphogenesis of a branching structure	1.081400e-2
GO:0010669	epithelial structure maintenance	1.088477e-2
GO:0042594	response to starvation	1.089642e-2
GO:0001763	morphogenesis of a branching structure	1.091422e-2
GO:0046165	alcohol biosynthetic process	1.098156e-2
GO:0006878	cellular copper ion homeostasis	1.104606e-2
GO:0043270	positive regulation of ion transport	1.112395e-2
GO:0030490	maturation of SSU-rRNA	1.114431e-2
GO:0018026	peptidyl-lysine monomethylation	1.114431e-2
GO:0072523	purine-containing compound catabolic process	1.133628e-2
GO:0008333	endosome to lysosome transport	1.140192e-2
GO:0001714	endodermal cell fate specification	1.152405e-2
GO:0016049	cell growth	1.162330e-2
GO:0032740	positive regulation of interleukin-17 production	1.166479e-2
GO:0060675	ureteric bud morphogenesis	1.168446e-2
GO:0001657	ureteric bud development	1.194902e-2
GO:0048521	negative regulation of behavior	1.201390e-2
GO:2000543	positive regulation of gastrulation	1.202965e-2
GO:0001656	metanephros development	1.208844e-2
GO:0015827	tryptophan transport	1.214723e-2
GO:0032700	negative regulation of interleukin-17 production	1.226401e-2
GO:0022617	extracellular matrix disassembly	1.228848e-2
GO:0051257	spindle midzone assembly involved in meiosis	1.230444e-2
GO:0009235	cobalamin metabolic process	1.230444e-2
GO:0007060	male meiosis chromosome segregation	1.230444e-2
GO:0055008	cardiac muscle tissue morphogenesis	1.234726e-2
GO:0021559	trigeminal nerve development	1.250862e-2
GO:0050686	negative regulation of mRNA processing	1.255136e-2
GO:0032543	mitochondrial translation	1.255136e-2
GO:0019348	dolichol metabolic process	1.268167e-2
GO:0034698	response to gonadotropin stimulus	1.298387e-2
GO:0048672	positive regulation of collateral sprouting	1.300302e-2
GO:0006000	fructose metabolic process	1.300822e-2
GO:0034622	cellular macromolecular complex assembly	1.310776e-2
GO:0060534	trachea cartilage development	1.315214e-2
GO:0050651	dermatan sulfate proteoglycan biosynthetic process	1.315214e-2
GO:0048265	response to pain	1.316381e-2
GO:0065003	macromolecular complex assembly	1.324759e-2
GO:0043161	proteasomal ubiquitin-dependent protein catabolic process	1.337869e-2
GO:0050806	positive regulation of synaptic transmission	1.346599e-2
GO:0048008	platelet-derived growth factor receptor signaling pathway	1.358243e-2
GO:0072009	nephron epithelium development	1.370162e-2
GO:0051081	nuclear envelope disassembly	1.383591e-2
GO:0035694	mitochondrial protein catabolic process	1.383591e-2
GO:0061015	snRNA import into nucleus	1.385864e-2
GO:0001880	Mullerian duct regression	1.389857e-2
GO:0046293	formaldehyde biosynthetic process	1.400376e-2
GO:0060133	somatotropin secreting cell development	1.400376e-2
GO:0043152	induction of bacterial agglutination	1.400376e-2
GO:0051966	regulation of synaptic transmission, glutamatergic	1.401923e-2
GO:0002449	lymphocyte mediated immunity	1.416243e-2
GO:0000302	response to reactive oxygen species	1.420796e-2
GO:0072124	regulation of glomerular mesangial cell proliferation	1.421591e-2
GO:0072148	epithelial cell fate commitment	1.421591e-2
GO:0032414	positive regulation of ion transmembrane transporter activity	1.430595e-2
GO:0051209	release of sequestered calcium ion into cytosol	1.475413e-2
GO:0032401	establishment of melanosome localization	1.481858e-2
GO:0060596	mammary placode formation	1.482651e-2
GO:0042524	negative regulation of tyrosine phosphorylation of Stat5 protein	1.483464e-2
GO:0060173	limb development	1.522296e-2
GO:0060433	bronchus development	1.541127e-2
GO:0072298	regulation of metanephric glomerulus development	1.541127e-2
GO:2000594	positive regulation of metanephric DCT cell differentiation	1.545697e-2
GO:0072305	negative regulation of mesenchymal stem cell apoptosis involved in metanephric nephron morphogenesis	1.545697e-2
GO:0050655	dermatan sulfate proteoglycan metabolic process	1.545697e-2
GO:0039003	pronephric field specification	1.545697e-2
GO:0048738	cardiac muscle tissue development	1.562223e-2
GO:0051318	G1 phase	1.578629e-2
GO:0000239	pachytene	1.581195e-2
GO:0003051	angiotensin-mediated drinking behavior	1.582946e-2
GO:0019047	provirus integration	1.587797e-2

GREAT analysis results for mouseGenomic Enrichment of Annotations Tool (GREAT, Nat Biotechnol. 2010 May;28(5):495-501) is used to identify, both in human and in mouse, the gene ontology terms of biological processes enriched given the predicted TFBSs, and evaluated the overlap in the top-500 gene ontology terms between human and mouse. For each novel motif, the P value for the overlap was then evaluated by calculating its relative rank with respect to this background distribution.<br>Analyst: Michiel de Hoon <br><br>link to source dataset <br>data

---

GO ID	GO Term	p-value
GO:0045780	positive regulation of bone resorption	1.420312e-11
GO:0090267	positive regulation of mitotic cell cycle spindle assembly checkpoint	1.746931e-10
GO:0034105	positive regulation of tissue remodeling	8.749481e-10
GO:0030502	negative regulation of bone mineralization	2.569866e-9
GO:0070168	negative regulation of biomineral tissue development	3.250123e-9
GO:0046627	negative regulation of insulin receptor signaling pathway	1.079422e-8
GO:0045124	regulation of bone resorption	1.932325e-8
GO:0006936	muscle contraction	2.381440e-8
GO:0048496	maintenance of organ identity	3.346899e-8
GO:0046850	regulation of bone remodeling	5.280895e-8
GO:0009236	cobalamin biosynthetic process	6.022777e-8
GO:0006953	acute-phase response	1.169967e-7
GO:0017196	N-terminal peptidyl-methionine acetylation	1.579771e-7
GO:0031100	organ regeneration	5.404450e-7
GO:0007059	chromosome segregation	5.930278e-7
GO:0014878	response to electrical stimulus involved in regulation of muscle adaptation	7.413020e-7
GO:0031987	locomotion involved in locomotory behavior	1.206404e-6
GO:0046626	regulation of insulin receptor signaling pathway	3.616568e-6
GO:0090231	regulation of spindle checkpoint	4.019155e-6
GO:0046341	CDP-diacylglycerol metabolic process	4.412856e-6
GO:0031161	phosphatidylinositol catabolic process	5.027169e-6
GO:0060986	endocrine hormone secretion	7.030690e-6
GO:0034337	RNA folding	7.110288e-6
GO:0034103	regulation of tissue remodeling	7.477467e-6
GO:0070166	enamel mineralization	7.484708e-6
GO:0061301	cerebellum vasculature morphogenesis	7.548455e-6
GO:0045210	FasL biosynthetic process	7.548455e-6
GO:0006348	chromatin silencing at telomere	7.650979e-6
GO:0044029	hypomethylation of CpG island	1.220624e-5
GO:0032846	positive regulation of homeostatic process	1.525064e-5
GO:0045948	positive regulation of translational initiation	1.578014e-5
GO:0050766	positive regulation of phagocytosis	1.838390e-5
GO:0018206	peptidyl-methionine modification	2.050036e-5
GO:0022613	ribonucleoprotein complex biogenesis	2.331510e-5
GO:0021987	cerebral cortex development	2.381616e-5
GO:0071843	cellular component biogenesis at cellular level	2.512803e-5
GO:2000279	negative regulation of DNA biosynthetic process	2.778756e-5
GO:0046960	sensitization	2.876436e-5
GO:0007076	mitotic chromosome condensation	3.010589e-5
GO:0002526	acute inflammatory response	3.234128e-5
GO:0030308	negative regulation of cell growth	3.289150e-5
GO:0050764	regulation of phagocytosis	4.069736e-5
GO:0030263	apoptotic chromosome condensation	4.634857e-5
GO:0030279	negative regulation of ossification	4.839492e-5
GO:0003012	muscle system process	4.936762e-5
GO:0000715	nucleotide-excision repair, DNA damage recognition	5.900484e-5
GO:0044030	regulation of DNA methylation	5.997888e-5
GO:0032402	melanosome transport	6.216704e-5
GO:0006941	striated muscle contraction	6.453133e-5
GO:0048633	positive regulation of skeletal muscle tissue growth	6.569273e-5
GO:0031099	regeneration	6.802116e-5
GO:0070986	left/right axis specification	7.416928e-5
GO:0048743	positive regulation of skeletal muscle fiber development	8.760720e-5
GO:0009235	cobalamin metabolic process	9.216508e-5
GO:0035106	operant conditioning	9.340357e-5
GO:0006370	mRNA capping	9.373235e-5
GO:0000028	ribosomal small subunit assembly	1.017542e-4
GO:0015992	proton transport	1.268675e-4
GO:0032800	receptor biosynthetic process	1.334633e-4
GO:0043049	otic placode formation	1.380418e-4
GO:0006818	hydrogen transport	1.443518e-4
GO:0021636	trigeminal nerve morphogenesis	1.451654e-4
GO:0045212	neurotransmitter receptor biosynthetic process	1.451654e-4
GO:0035572	N-terminal peptidyl-serine dimethylation	1.463473e-4
GO:0035573	N-terminal peptidyl-serine trimethylation	1.463473e-4
GO:0021528	commissural neuron differentiation in spinal cord	1.463473e-4
GO:0018012	N-terminal peptidyl-alanine trimethylation	1.463473e-4
GO:0018016	N-terminal peptidyl-proline dimethylation	1.463473e-4
GO:0022618	ribonucleoprotein complex assembly	1.721092e-4
GO:0042640	anagen	1.748721e-4
GO:0003148	outflow tract septum morphogenesis	1.749273e-4
GO:0060972	left/right pattern formation	2.671110e-4
GO:0051904	pigment granule transport	2.671110e-4
GO:0032911	negative regulation of transforming growth factor beta1 production	2.671110e-4
GO:0006888	ER to Golgi vesicle-mediated transport	2.827744e-4
GO:0060286	flagellar cell motility	2.919194e-4
GO:0006601	creatine biosynthetic process	2.919194e-4
GO:0071826	ribonucleoprotein complex subunit organization	3.077729e-4
GO:0042274	ribosomal small subunit biogenesis	3.454161e-4
GO:0009452	RNA capping	3.523389e-4
GO:0032401	establishment of melanosome localization	3.552895e-4
GO:0007080	mitotic metaphase plate congression	3.552895e-4
GO:0032274	gonadotropin secretion	3.640759e-4
GO:0035426	extracellular matrix-cell signaling	3.831357e-4
GO:0030948	negative regulation of vascular endothelial growth factor receptor signaling pathway	3.839003e-4
GO:0031365	N-terminal protein amino acid modification	3.871575e-4
GO:0021895	cerebral cortex neuron differentiation	4.145649e-4
GO:0000070	mitotic sister chromatid segregation	4.322167e-4
GO:0048631	regulation of skeletal muscle tissue growth	4.606942e-4
GO:0032400	melanosome localization	4.845019e-4
GO:0021543	pallium development	4.854135e-4
GO:2000171	negative regulation of dendrite development	5.124227e-4
GO:0048643	positive regulation of skeletal muscle tissue development	5.180843e-4
GO:0060371	regulation of atrial cardiomyocyte membrane depolarization	5.527212e-4
GO:0061304	retinal blood vessel morphogenesis	5.881663e-4
GO:0090288	negative regulation of cellular response to growth factor stimulus	6.370132e-4
GO:0040030	regulation of molecular function, epigenetic	6.720007e-4
GO:0048672	positive regulation of collateral sprouting	6.720007e-4
GO:0009957	epidermal cell fate specification	6.720007e-4
GO:0048820	hair follicle maturation	7.020572e-4
GO:0032908	regulation of transforming growth factor beta1 production	7.386167e-4
GO:2000278	regulation of DNA biosynthetic process	7.712180e-4
GO:0045746	negative regulation of Notch signaling pathway	7.712180e-4
GO:0000819	sister chromatid segregation	7.997461e-4
GO:0097152	mesenchymal cell apoptosis	8.275811e-4
GO:0046958	nonassociative learning	8.294566e-4
GO:0045930	negative regulation of mitotic cell cycle	8.402849e-4
GO:0007191	activation of adenylate cyclase activity by dopamine receptor signaling pathway	8.660838e-4
GO:0021997	neural plate axis specification	9.884645e-4
GO:0051905	establishment of pigment granule localization	1.040475e-3
GO:0006054	N-acetylneuraminate metabolic process	1.040475e-3
GO:0048640	negative regulation of developmental growth	1.078404e-3
GO:0046605	regulation of centrosome cycle	1.090338e-3
GO:0035239	tube morphogenesis	1.106616e-3
GO:0042384	cilium assembly	1.114175e-3
GO:0042989	sequestering of actin monomers	1.119745e-3
GO:0060809	mesodermal to mesenchymal transition involved in gastrulation	1.121239e-3
GO:0060315	negative regulation of ryanodine-sensitive calcium-release channel activity	1.121239e-3
GO:0006587	serotonin biosynthetic process from tryptophan	1.150037e-3
GO:0051875	pigment granule localization	1.160142e-3
GO:0046381	CMP-N-acetylneuraminate metabolic process	1.176541e-3
GO:0042254	ribosome biogenesis	1.329560e-3
GO:0050886	endocrine process	1.336682e-3
GO:0043201	response to leucine	1.368560e-3
GO:0071922	regulation of cohesin localization to chromatin	1.375465e-3
GO:0071635	negative regulation of transforming growth factor beta production	1.386255e-3
GO:0060896	neural plate pattern specification	1.386255e-3
GO:0006659	phosphatidylserine biosynthetic process	1.519035e-3
GO:0045749	negative regulation of S phase of mitotic cell cycle	1.564434e-3
GO:0016601	Rac protein signal transduction	1.665417e-3
GO:0007063	regulation of sister chromatid cohesion	1.699847e-3
GO:0010388	cullin deneddylation	1.699953e-3
GO:0008361	regulation of cell size	1.775884e-3
GO:0006379	mRNA cleavage	1.786265e-3
GO:0048148	behavioral response to cocaine	1.881709e-3
GO:0003127	detection of nodal flow	1.886994e-3
GO:0030500	regulation of bone mineralization	1.895174e-3
GO:0021602	cranial nerve morphogenesis	1.946140e-3
GO:0042523	positive regulation of tyrosine phosphorylation of Stat5 protein	1.962062e-3
GO:0061387	regulation of extent of cell growth	2.155559e-3
GO:0045494	photoreceptor cell maintenance	2.244428e-3
GO:0006552	leucine catabolic process	2.269921e-3
GO:0031104	dendrite regeneration	2.269921e-3
GO:0045234	protein palmitoleylation	2.269921e-3
GO:0006948	induction by virus of host cell-cell fusion	2.269921e-3
GO:0048671	negative regulation of collateral sprouting	2.287244e-3
GO:0006096	glycolysis	2.315785e-3
GO:0032971	regulation of muscle filament sliding	2.366523e-3
GO:0090084	negative regulation of inclusion body assembly	2.413883e-3
GO:0070286	axonemal dynein complex assembly	2.413883e-3
GO:0021545	cranial nerve development	2.427980e-3
GO:0051310	metaphase plate congression	2.490106e-3
GO:0070167	regulation of biomineral tissue development	2.490152e-3
GO:0090305	nucleic acid phosphodiester bond hydrolysis	2.598531e-3
GO:0010460	positive regulation of heart rate	2.681853e-3
GO:0050808	synapse organization	2.683047e-3
GO:0001542	ovulation from ovarian follicle	2.715559e-3
GO:0060285	ciliary cell motility	2.742153e-3
GO:0002074	extraocular skeletal muscle development	2.742153e-3
GO:0031573	intra-S DNA damage checkpoint	2.752846e-3
GO:0048010	vascular endothelial growth factor receptor signaling pathway	2.844867e-3
GO:0010273	detoxification of copper ion	2.914959e-3
GO:0042701	progesterone secretion	3.009691e-3
GO:0042321	negative regulation of circadian sleep/wake cycle, sleep	3.099718e-3
GO:0032868	response to insulin stimulus	3.140155e-3
GO:0033148	positive regulation of estrogen receptor signaling pathway	3.283376e-3
GO:0003065	positive regulation of heart rate by epinephrine	3.283376e-3
GO:0015986	ATP synthesis coupled proton transport	3.307361e-3
GO:0040019	positive regulation of embryonic development	3.382855e-3
GO:0042396	phosphagen biosynthetic process	3.487802e-3
GO:0010833	telomere maintenance via telomere lengthening	3.487802e-3
GO:0006269	DNA replication, synthesis of RNA primer	3.487802e-3
GO:0006542	glutamine biosynthetic process	3.487802e-3
GO:0006406	mRNA export from nucleus	3.505841e-3
GO:0021570	rhombomere 4 development	3.535309e-3
GO:0021892	cerebral cortex GABAergic interneuron differentiation	3.536391e-3
GO:0006446	regulation of translational initiation	3.674911e-3
GO:0045213	neurotransmitter receptor metabolic process	3.739055e-3
GO:0060982	coronary artery morphogenesis	3.883697e-3
GO:0021853	cerebral cortex GABAergic interneuron migration	3.907602e-3
GO:0051303	establishment of chromosome localization	3.950414e-3
GO:0030262	apoptotic nuclear change	3.993393e-3
GO:0031442	positive regulation of mRNA 3'-end processing	4.202888e-3
GO:0050685	positive regulation of mRNA processing	4.204332e-3
GO:0006474	N-terminal protein amino acid acetylation	4.211543e-3
GO:0046813	virion attachment, binding of host cell surface receptor	4.230322e-3
GO:0042448	progesterone metabolic process	4.320892e-3
GO:0021796	cerebral cortex regionalization	4.360293e-3
GO:0045844	positive regulation of striated muscle tissue development	4.624828e-3
GO:0032413	negative regulation of ion transmembrane transporter activity	4.639008e-3
GO:0007413	axonal fasciculation	4.703162e-3
GO:0021564	vagus nerve development	4.767258e-3
GO:0060486	Clara cell differentiation	4.825862e-3
GO:0000082	G1/S transition of mitotic cell cycle	4.848848e-3
GO:0061338	atrioventricular node impulse conduction delay	4.887498e-3
GO:0031585	regulation of inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity	5.002492e-3
GO:0045807	positive regulation of endocytosis	5.045949e-3
GO:0060017	parathyroid gland development	5.313027e-3
GO:0060158	activation of phospholipase C activity by dopamine receptor signaling pathway	5.368896e-3
GO:0046475	glycerophospholipid catabolic process	5.368896e-3
GO:0045039	protein import into mitochondrial inner membrane	5.368896e-3
GO:0046323	glucose import	5.368896e-3
GO:0033599	regulation of mammary gland epithelial cell proliferation	5.513594e-3
GO:0071600	otic vesicle morphogenesis	5.515417e-3
GO:0046339	diacylglycerol metabolic process	5.693181e-3
GO:2000121	regulation of removal of superoxide radicals	5.721480e-3
GO:0010501	RNA secondary structure unwinding	5.854079e-3
GO:0002302	CD8-positive, alpha-beta T cell differentiation involved in immune response	5.854079e-3
GO:0007178	transmembrane receptor protein serine/threonine kinase signaling pathway	5.913108e-3
GO:0060033	anatomical structure regression	5.957241e-3
GO:0007368	determination of left/right symmetry	5.986206e-3
GO:0070327	thyroid hormone transport	6.151555e-3
GO:0006650	glycerophospholipid metabolic process	6.263172e-3
GO:0042438	melanin biosynthetic process	6.282875e-3
GO:0042255	ribosome assembly	6.282875e-3
GO:0006654	phosphatidic acid biosynthetic process	6.282875e-3
GO:0051180	vitamin transport	6.325364e-3
GO:0030947	regulation of vascular endothelial growth factor receptor signaling pathway	6.377071e-3
GO:0021843	substrate-independent telencephalic tangential interneuron migration	6.522412e-3
GO:0060528	secretory columnal luminar epithelial cell differentiation involved in prostate glandular acinus development	6.603829e-3
GO:0003062	regulation of heart rate by chemical signal	6.603829e-3
GO:0051329	interphase of mitotic cell cycle	6.697662e-3
GO:0003015	heart process	6.775973e-3
GO:0008380	RNA splicing	6.777028e-3
GO:0046168	glycerol-3-phosphate catabolic process	6.787112e-3
GO:0035880	embryonic nail plate morphogenesis	6.787112e-3
GO:0006658	phosphatidylserine metabolic process	6.794499e-3
GO:0006921	cellular component disassembly involved in apoptosis	6.837617e-3
GO:0045823	positive regulation of heart contraction	6.842977e-3
GO:0045955	negative regulation of calcium ion-dependent exocytosis	7.156125e-3
GO:0033119	negative regulation of RNA splicing	7.184855e-3
GO:0043501	skeletal muscle adaptation	7.251084e-3
GO:0031440	regulation of mRNA 3'-end processing	7.591152e-3
GO:0007064	mitotic sister chromatid cohesion	7.591152e-3
GO:0021559	trigeminal nerve development	7.591152e-3
GO:0032972	regulation of muscle filament sliding speed	7.637371e-3
GO:0001708	cell fate specification	7.639036e-3
GO:0009799	specification of symmetry	7.723016e-3
GO:0070474	positive regulation of uterine smooth muscle contraction	7.829132e-3
GO:0090287	regulation of cellular response to growth factor stimulus	7.902643e-3
GO:0030261	chromosome condensation	7.960088e-3
GO:0007617	mating behavior	8.012199e-3
GO:0048011	nerve growth factor receptor signaling pathway	8.099505e-3
GO:0048193	Golgi vesicle transport	8.108840e-3
GO:0016525	negative regulation of angiogenesis	8.176477e-3
GO:0051795	positive regulation of catagen	8.542385e-3
GO:0032804	negative regulation of low-density lipoprotein particle receptor catabolic process	8.904551e-3
GO:0009225	nucleotide-sugar metabolic process	8.907861e-3
GO:0048818	positive regulation of hair follicle maturation	9.296797e-3
GO:0032912	negative regulation of transforming growth factor beta2 production	9.296797e-3
GO:0061337	cardiac conduction	9.512504e-3
GO:0048670	regulation of collateral sprouting	9.815016e-3
GO:0002027	regulation of heart rate	9.877738e-3
GO:0051325	interphase	9.959523e-3
GO:0071375	cellular response to peptide hormone stimulus	1.000230e-2
GO:0032938	negative regulation of translation in response to oxidative stress	1.005056e-2
GO:2001051	positive regulation of tendon cell differentiation	1.005056e-2
GO:0021509	roof plate formation	1.005056e-2
GO:0030578	PML body organization	1.005056e-2
GO:0000379	tRNA-type intron splice site recognition and cleavage	1.005056e-2
GO:0045014	negative regulation of transcription by glucose	1.009325e-2
GO:0003266	regulation of secondary heart field cardioblast proliferation	1.014593e-2
GO:0021783	preganglionic parasympathetic nervous system development	1.092413e-2
GO:0051567	histone H3-K9 methylation	1.108789e-2
GO:0048639	positive regulation of developmental growth	1.108814e-2
GO:0002009	morphogenesis of an epithelium	1.122038e-2
GO:0033762	response to glucagon stimulus	1.134143e-2
GO:0042522	regulation of tyrosine phosphorylation of Stat5 protein	1.134143e-2
GO:0060564	negative regulation of mitotic anaphase-promoting complex activity	1.136686e-2
GO:0021893	cerebral cortex GABAergic interneuron fate commitment	1.136686e-2
GO:0021882	regulation of transcription from RNA polymerase II promoter involved in forebrain neuron fate commitment	1.136686e-2
GO:0019062	virion attachment to host cell surface receptor	1.136686e-2
GO:0015872	dopamine transport	1.145702e-2
GO:0046532	regulation of photoreceptor cell differentiation	1.145702e-2
GO:0009084	glutamine family amino acid biosynthetic process	1.145702e-2
GO:0043954	cellular component maintenance	1.153643e-2
GO:0072337	modified amino acid transport	1.175861e-2
GO:0048708	astrocyte differentiation	1.191899e-2
GO:0051276	chromosome organization	1.192010e-2
GO:0001558	regulation of cell growth	1.195674e-2
GO:0030517	negative regulation of axon extension	1.219410e-2
GO:0030728	ovulation	1.244737e-2
GO:0072321	chaperone-mediated protein transport	1.273026e-2
GO:0060738	epithelial-mesenchymal signaling involved in prostate gland development	1.273026e-2
GO:0006390	transcription from mitochondrial promoter	1.274305e-2
GO:0042843	D-xylose catabolic process	1.275417e-2
GO:0045684	positive regulation of epidermis development	1.275620e-2
GO:0030217	T cell differentiation	1.315199e-2
GO:0060666	dichotomous subdivision of terminal units involved in salivary gland branching	1.321106e-2
GO:0014821	phasic smooth muscle contraction	1.356002e-2
GO:0030278	regulation of ossification	1.366478e-2
GO:0003254	regulation of membrane depolarization	1.368780e-2
GO:0072348	sulfur compound transport	1.371568e-2
GO:2000008	regulation of protein localization at cell surface	1.371568e-2
GO:0030432	peristalsis	1.383523e-2
GO:0006405	RNA export from nucleus	1.390141e-2
GO:0072109	glomerular mesangium development	1.396167e-2
GO:0072061	inner medullary collecting duct development	1.418304e-2
GO:0072060	outer medullary collecting duct development	1.418304e-2
GO:2001037	positive regulation of tongue muscle cell differentiation	1.418304e-2
GO:0016332	establishment or maintenance of polarity of embryonic epithelium	1.418304e-2
GO:0019405	alditol catabolic process	1.418304e-2
GO:0021644	vagus nerve morphogenesis	1.418304e-2
GO:0060428	lung epithelium development	1.436511e-2
GO:0051926	negative regulation of calcium ion transport	1.456473e-2
GO:0019067	viral assembly, maturation, egress, and release	1.475120e-2
GO:0048521	negative regulation of behavior	1.499753e-2
GO:0007613	memory	1.543549e-2
GO:0006582	melanin metabolic process	1.551394e-2
GO:0000723	telomere maintenance	1.555057e-2
GO:0031929	TOR signaling cascade	1.557006e-2
GO:0060048	cardiac muscle contraction	1.571167e-2
GO:0003051	angiotensin-mediated drinking behavior	1.572589e-2
GO:0051643	endoplasmic reticulum localization	1.572589e-2
GO:0071502	cellular response to temperature stimulus	1.573581e-2
GO:0048243	norepinephrine secretion	1.573581e-2
GO:0014827	intestine smooth muscle contraction	1.573581e-2
GO:0044275	cellular carbohydrate catabolic process	1.576267e-2
GO:0032869	cellular response to insulin stimulus	1.622792e-2
GO:0051209	release of sequestered calcium ion into cytosol	1.663977e-2
GO:0021515	cell differentiation in spinal cord	1.683818e-2
GO:0008050	female courtship behavior	1.691131e-2
GO:0048486	parasympathetic nervous system development	1.693746e-2
GO:0046782	regulation of viral transcription	1.720157e-2
GO:0051436	negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle	1.735936e-2
GO:0048251	elastic fiber assembly	1.801628e-2
GO:0061113	pancreas morphogenesis	1.807114e-2
GO:0007221	positive regulation of transcription of Notch receptor target	1.807114e-2
GO:0032844	regulation of homeostatic process	1.874334e-2
GO:0048843	negative regulation of axon extension involved in axon guidance	1.878851e-2
GO:0051983	regulation of chromosome segregation	1.892060e-2
GO:0048857	neural nucleus development	1.892060e-2
GO:0071934	thiamine transmembrane transport	1.898350e-2
GO:0043420	anthranilate metabolic process	1.898350e-2
GO:0000053	argininosuccinate metabolic process	1.898350e-2
GO:0034516	response to vitamin B6	1.898350e-2
GO:0021898	commitment of multipotent stem cells to neuronal lineage in forebrain	1.908383e-2
GO:0061298	retina vasculature development in camera-type eye	1.914710e-2
GO:0046533	negative regulation of photoreceptor cell differentiation	1.914710e-2
GO:0090083	regulation of inclusion body assembly	1.927919e-2
GO:0015991	ATP hydrolysis coupled proton transport	1.958062e-2
GO:0048483	autonomic nervous system development	1.966373e-2
GO:0070125	mitochondrial translational elongation	1.971326e-2
GO:0060562	epithelial tube morphogenesis	2.000368e-2
GO:0042053	regulation of dopamine metabolic process	2.011871e-2
GO:0014807	regulation of somitogenesis	2.089958e-2
GO:0003270	Notch signaling pathway involved in regulation of secondary heart field cardioblast proliferation	2.089958e-2
GO:0046784	intronless viral mRNA export from host nucleus	2.112200e-2
GO:0014823	response to activity	2.122248e-2
GO:0051937	catecholamine transport	2.143822e-2
GO:0032200	telomere organization	2.143822e-2
GO:0030837	negative regulation of actin filament polymerization	2.169952e-2
GO:0000959	mitochondrial RNA metabolic process	2.184192e-2
GO:0009914	hormone transport	2.206691e-2
GO:0033059	cellular pigmentation	2.231299e-2
GO:0006364	rRNA processing	2.232014e-2
GO:0018208	peptidyl-proline modification	2.233955e-2
GO:0019805	quinolinate biosynthetic process	2.248558e-2
GO:0000722	telomere maintenance via recombination	2.248558e-2
GO:0006278	RNA-dependent DNA replication	2.250966e-2
GO:0043374	CD8-positive, alpha-beta T cell differentiation	2.250966e-2
GO:0050771	negative regulation of axonogenesis	2.255651e-2
GO:0046174	polyol catabolic process	2.280670e-2
GO:0001732	formation of translation initiation complex	2.280670e-2
GO:0021940	positive regulation of cerebellar granule cell precursor proliferation	2.298902e-2
GO:0000245	spliceosome assembly	2.329724e-2
GO:0030516	regulation of axon extension	2.343736e-2
GO:0046365	monosaccharide catabolic process	2.353402e-2
GO:0021675	nerve development	2.373826e-2
GO:0048255	mRNA stabilization	2.376466e-2
GO:0001711	endodermal cell fate commitment	2.380805e-2
GO:0045926	negative regulation of growth	2.414269e-2
GO:0010977	negative regulation of neuron projection development	2.446970e-2
GO:0051924	regulation of calcium ion transport	2.450386e-2
GO:0045065	cytotoxic T cell differentiation	2.460300e-2
GO:0007493	endodermal cell fate determination	2.460300e-2
GO:0048378	regulation of lateral mesodermal cell fate specification	2.480521e-2
GO:0006467	protein thiol-disulfide exchange	2.480521e-2
GO:0001306	age-dependent response to oxidative stress	2.480521e-2
GO:0016577	histone demethylation	2.506868e-2
GO:0000278	mitotic cell cycle	2.520335e-2
GO:0030513	positive regulation of BMP signaling pathway	2.527942e-2
GO:0010224	response to UV-B	2.543803e-2
GO:0003272	endocardial cushion formation	2.545851e-2
GO:0019637	organophosphate metabolic process	2.603603e-2
GO:2000791	negative regulation of mesenchymal cell proliferation involved in lung development	2.605884e-2
GO:2000795	negative regulation of epithelial cell proliferation involved in lung morphogenesis	2.605884e-2
GO:0021740	principal sensory nucleus of trigeminal nerve development	2.605884e-2
GO:0061141	lung ciliated cell differentiation	2.605884e-2
GO:0042733	embryonic digit morphogenesis	2.620570e-2
GO:0007208	activation of phospholipase C activity by serotonin receptor signaling pathway	2.623078e-2
GO:0061143	alveolar primary septum development	2.623078e-2
GO:0002897	positive regulation of central B cell tolerance induction	2.623078e-2
GO:0002508	central tolerance induction	2.623078e-2
GO:0050434	positive regulation of viral transcription	2.639827e-2
GO:0042069	regulation of catecholamine metabolic process	2.662501e-2
GO:0021978	telencephalon regionalization	2.662501e-2
GO:0071218	cellular response to misfolded protein	2.689497e-2
GO:0018119	peptidyl-cysteine S-nitrosylation	2.689497e-2
GO:0048608	reproductive structure development	2.709848e-2
GO:0045668	negative regulation of osteoblast differentiation	2.722530e-2
GO:0007411	axon guidance	2.726640e-2
GO:0010838	positive regulation of keratinocyte proliferation	2.756531e-2
GO:0007619	courtship behavior	2.756531e-2
GO:0005513	detection of calcium ion	2.756531e-2
GO:0071526	semaphorin-plexin signaling pathway	2.777767e-2
GO:0051968	positive regulation of synaptic transmission, glutamatergic	2.782737e-2
GO:0051282	regulation of sequestering of calcium ion	2.849292e-2
GO:0030900	forebrain development	2.857427e-2
GO:0021936	regulation of cerebellar granule cell precursor proliferation	2.880844e-2
GO:0090370	negative regulation of cholesterol efflux	2.907575e-2
GO:0042297	vocal learning	2.907575e-2
GO:0032902	nerve growth factor production	2.907575e-2
GO:0046015	regulation of transcription by glucose	2.912268e-2
GO:0007067	mitosis	2.939871e-2
GO:0060510	Type II pneumocyte differentiation	2.956462e-2
GO:0006882	cellular zinc ion homeostasis	2.984239e-2
GO:0085029	extracellular matrix assembly	2.986404e-2
GO:0048352	paraxial mesoderm structural organization	3.020815e-2
GO:0006433	prolyl-tRNA aminoacylation	3.020815e-2
GO:0021998	neural plate mediolateral regionalization	3.020815e-2
GO:0014874	response to stimulus involved in regulation of muscle adaptation	3.073117e-2
GO:0090100	positive regulation of transmembrane receptor protein serine/threonine kinase signaling pathway	3.091899e-2
GO:0006323	DNA packaging	3.155028e-2
GO:0007062	sister chromatid cohesion	3.156694e-2
GO:0006482	protein demethylation	3.156694e-2
GO:0042473	outer ear morphogenesis	3.162857e-2
GO:0034622	cellular macromolecular complex assembly	3.167311e-2
GO:0016072	rRNA metabolic process	3.199160e-2
GO:0009887	organ morphogenesis	3.209395e-2
GO:0071599	otic vesicle development	3.210419e-2
GO:0001503	ossification	3.226824e-2
GO:0006924	activation-induced cell death of T cells	3.239098e-2
GO:0035295	tube development	3.242131e-2
GO:0006261	DNA-dependent DNA replication	3.307259e-2
GO:0006644	phospholipid metabolic process	3.316702e-2
GO:0070431	nucleotide-binding oligomerization domain containing 2 signaling pathway	3.370885e-2
GO:0051612	negative regulation of serotonin uptake	3.370885e-2
GO:0042738	exogenous drug catabolic process	3.370885e-2
GO:0014732	skeletal muscle atrophy	3.410227e-2
GO:0060430	lung saccule development	3.433834e-2
GO:0030421	defecation	3.440710e-2
GO:0019442	tryptophan catabolic process to acetyl-CoA	3.440710e-2
GO:0006526	arginine biosynthetic process	3.440710e-2
GO:0018931	naphthalene metabolic process	3.440710e-2
GO:0007214	gamma-aminobutyric acid signaling pathway	3.473297e-2
GO:0006417	regulation of translation	3.486346e-2
GO:0022415	viral reproductive process	3.549523e-2
GO:0000087	M phase of mitotic cell cycle	3.555879e-2
GO:0048285	organelle fission	3.567061e-2
GO:0007512	adult heart development	3.571978e-2
GO:0055069	zinc ion homeostasis	3.577101e-2
GO:0008343	adult feeding behavior	3.586517e-2
GO:0021612	facial nerve structural organization	3.616019e-2
GO:0071400	cellular response to oleic acid	3.616019e-2
GO:0001840	neural plate development	3.718277e-2
GO:0071377	cellular response to glucagon stimulus	3.767977e-2
GO:0006600	creatine metabolic process	3.767977e-2
GO:0006007	glucose catabolic process	3.786774e-2
GO:2000179	positive regulation of neural precursor cell proliferation	3.847239e-2
GO:0006890	retrograde vesicle-mediated transport, Golgi to ER	3.859821e-2
GO:0072054	renal outer medulla development	3.870058e-2
GO:0001880	Mullerian duct regression	3.870058e-2
GO:0015805	S-adenosylmethionine transport	3.881736e-2
GO:0061146	Peyer's patch morphogenesis	3.903808e-2
GO:0001731	formation of translation preinitiation complex	3.903808e-2
GO:0007495	visceral mesoderm-endoderm interaction involved in midgut development	3.903808e-2
GO:0072044	collecting duct development	3.922357e-2
GO:0002051	osteoblast fate commitment	3.954612e-2
GO:0001661	conditioned taste aversion	3.954612e-2
GO:0019058	viral infectious cycle	3.959244e-2
GO:0060271	cilium morphogenesis	3.973799e-2
GO:0051496	positive regulation of stress fiber assembly	3.974618e-2
GO:0010629	negative regulation of gene expression	3.991769e-2
GO:0048752	semicircular canal morphogenesis	4.012710e-2
GO:0000724	double-strand break repair via homologous recombination	4.060359e-2
GO:0030050	vesicle transport along actin filament	4.132928e-2
GO:0048268	clathrin coat assembly	4.171651e-2
GO:0003219	cardiac right ventricle formation	4.171651e-2
GO:0003310	pancreatic A cell differentiation	4.171651e-2
GO:0051918	negative regulation of fibrinolysis	4.182314e-2
GO:0006901	vesicle coating	4.329856e-2
GO:0002635	negative regulation of germinal center formation	4.342897e-2
GO:0046502	uroporphyrinogen III metabolic process	4.342897e-2
GO:0072303	positive regulation of glomerular metanephric mesangial cell proliferation	4.342897e-2
GO:0033590	response to cobalamin	4.342897e-2
GO:0045924	regulation of female receptivity	4.343417e-2
GO:2000058	regulation of protein ubiquitination involved in ubiquitin-dependent protein catabolic process	4.361145e-2
GO:0071285	cellular response to lithium ion	4.361145e-2
GO:0071158	positive regulation of cell cycle arrest	4.411467e-2
GO:0016338	calcium-independent cell-cell adhesion	4.481916e-2
GO:0010898	positive regulation of triglyceride catabolic process	4.491616e-2
GO:0007292	female gamete generation	4.536219e-2
GO:0001706	endoderm formation	4.544419e-2
GO:0007625	grooming behavior	4.545581e-2
GO:0071634	regulation of transforming growth factor beta production	4.584097e-2
GO:0047497	mitochondrion transport along microtubule	4.592131e-2
GO:0001843	neural tube closure	4.624222e-2
GO:0090304	nucleic acid metabolic process	4.636793e-2
GO:0002663	positive regulation of B cell tolerance induction	4.684839e-2