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MCL coexpression mm9:1611: Difference between revisions

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{{MCL_coexpression_mm9
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19011,0.0845301845292944,0,0,0|gostat_on_MCL_coexpression=GO:0043534;blood vessel endothelial cell migration;0.0211130385121345;11806!GO:0008035;high-density lipoprotein binding;0.0211130385121345;11806!GO:0033344;cholesterol efflux;0.0211130385121345;11806!GO:0030300;regulation of cholesterol absorption;0.0211130385121345;11806!GO:0030299;cholesterol absorption;0.0211130385121345;11806!GO:0044241;lipid digestion;0.0211130385121345;11806!GO:0051346;negative regulation of hydrolase activity;0.0211130385121345;11806!GO:0017127;cholesterol transporter activity;0.0211130385121345;11806!GO:0043542;endothelial cell migration;0.0211130385121345;11806!GO:0015248;sterol transporter activity;0.0211130385121345;11806!GO:0001935;endothelial cell proliferation;0.0211130385121345;11806!GO:0050892;intestinal absorption;0.0211130385121345;11806!GO:0008211;glucocorticoid metabolic process;0.0211130385121345;11806!GO:0030325;adrenal gland development;0.0211130385121345;11806!GO:0019915;sequestering of lipid;0.021892603712342;11806!GO:0008034;lipoprotein binding;0.025103850034829;11806!GO:0022600;digestive system process;0.025103850034829;11806!GO:0030301;cholesterol transport;0.0255301778494967;11806!GO:0015918;sterol transport;0.0259112507101296;11806!GO:0006695;cholesterol biosynthetic process;0.03607532601436;11806!GO:0016126;sterol biosynthetic 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|coexpression_dpi_cluster_scores_median=0,0.840895010810998,1.22852799425399,0.280440101118034,0.426056828494341,0.642545548155406,0.681925343658499,0.107702823486292,0,0,0,0,0,0,0,0,0,0.0291182268954187,0.115143199681363,0,0.0682179984609265,0,0.0421217968534449,0.8345210098887,0.873403255055908,1.00807663476624,0.963054474756439,0.928637604657646,0.626381241572423,0.546579835718164,0.953387477824743,0,0,0,0.19802531727213,0.32018944962401,0.257655516352174,0,0,0.0619393238064139,0,0,0.0158151391723993,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0.107511441879825,0,0,0,0,0,0,0,0,0,0,0.226626523502606,0.0754361084338262,0,0,0,0,0,0.0482820047261801,0,1.552702465086,0.075830397111094,0,0,0,0,0,0,0,0.54022285266325,0,0,0.0519509775191307,0,0,0,0,0,0,0,0.0076288172781711,0.0509235292940968,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0.0720574434660652,0.0701590301280712,0.0467793790710282,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0.742460859731346,0.52892377998733,0,0,0.0526429550379996,0.170999254772478,0.221970542984498,0.367650206374191,0.352135412593213,0.394852621376609,0.38330516349764,0.362798559526171,0.336416607008679,0.306743118957628,0.270574546258304,0.600659208620972,0,0,0,0,0,0,0.0266298923127834,0.0597943799295356,0,0,0,0,0,0,0,0,0.064024765547458,0.0346343074390951,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0.0109619364239641,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0.0998284739419172,0,0.0979294923068659,0,0,0,0,0,0,0,0,0,0,0,0,0.118918080006488,0.0520584221493134,0,0,0.0494606362651129,0,0,0.439156574576173,0,0,0,0.102354414814409,0,0,0,0,0.056886356216389,0.105986777695408,0,0,0,0,0,0.0857765460992942,0,0.034489466458534,0.100975358632432,0,0,0,0,0,0,0.0527554171614426,0.0677982110636083,0.0336632536088659,0,0,0,0,0.255106923844992,0.206333480896505,0.114989476349524,0.0658264940482259,0.0715236385554987,0.219508547413742,0.0935585710841254,0.0598244186619439,0.147325594122017,0.0894177291216067,0.177285640662167,0.215848316102587,0.163416865637375,0.27766505709663,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0.120876255993453,0,0.063627699902974,0.104524160556698,0,0.0763037466917402,0.0690411384905589,0,0.0905291472420136,0.072589682481754,0.115371650306916,0.112067779638927,0.128033729919821,0,0.092873634605593,0.0763334321280384,0.0748964051866952,0.0352754493378881,0.0729583017401753,0,0.0208139708923591,0,0.0141989440459893,0.0408018333703219,0,0.0625582350728301,0.0421169789527018,0,0.056801622819011,0.0845301845292944,0,0,0
|gostat_on_MCL_coexpression=GO:0043534;blood vessel endothelial cell migration;0.0211130385121345;11806!GO:0008035;high-density lipoprotein binding;0.0211130385121345;11806!GO:0033344;cholesterol efflux;0.0211130385121345;11806!GO:0030300;regulation of cholesterol absorption;0.0211130385121345;11806!GO:0030299;cholesterol absorption;0.0211130385121345;11806!GO:0044241;lipid digestion;0.0211130385121345;11806!GO:0051346;negative regulation of hydrolase activity;0.0211130385121345;11806!GO:0017127;cholesterol transporter activity;0.0211130385121345;11806!GO:0043542;endothelial cell migration;0.0211130385121345;11806!GO:0015248;sterol transporter activity;0.0211130385121345;11806!GO:0001935;endothelial cell proliferation;0.0211130385121345;11806!GO:0050892;intestinal absorption;0.0211130385121345;11806!GO:0008211;glucocorticoid metabolic process;0.0211130385121345;11806!GO:0030325;adrenal gland development;0.0211130385121345;11806!GO:0019915;sequestering of lipid;0.021892603712342;11806!GO:0008034;lipoprotein binding;0.025103850034829;11806!GO:0022600;digestive system process;0.025103850034829;11806!GO:0030301;cholesterol transport;0.0255301778494967;11806!GO:0015918;sterol transport;0.0259112507101296;11806!GO:0006695;cholesterol biosynthetic process;0.03607532601436;11806!GO:0016126;sterol biosynthetic process;0.0452546430490102;11806!
|ontology_enrichment_celltype=CL:0002563!8.64e-10!9;CL:0002251!8.64e-10!9;CL:0000239!2.02e-07!6;CL:0000677!2.02e-07!6;CL:0000212!2.02e-07!6;CL:0000584!2.02e-07!6
|ontology_enrichment_disease=
|ontology_enrichment_uberon=UBERON:0000160!2.85e-23!31;UBERON:0000344!5.80e-16!15;UBERON:0005409!8.08e-16!47;UBERON:0001242!7.51e-14!13;UBERON:0000060!7.51e-14!13;UBERON:0001262!7.51e-14!13;UBERON:0004786!7.51e-14!13;UBERON:0004923!5.25e-12!24;UBERON:0004119!8.56e-10!118;UBERON:0000925!8.56e-10!118;UBERON:0006595!8.56e-10!118;UBERON:0003350!8.64e-10!9;UBERON:0004808!8.64e-10!9;UBERON:0001277!8.64e-10!9;UBERON:0001007!1.50e-09!116;UBERON:0001555!1.50e-09!116;UBERON:0007026!1.50e-09!116;UBERON:0004921!2.00e-08!114;UBERON:0000485!1.78e-07!11
}}

Latest revision as of 17:12, 17 September 2013


Phase1 CAGE Peaks

 Short description
Mm9::chr12:103521071..103521081,+p7@Rin3
Mm9::chr19:29436320..29436384,-p1@5033414D02Rik
Mm9::chr1:87857604..87857648,-p1@Gpr55
Mm9::chr4:133899797..133899824,+p5@Slc30a2
Mm9::chr9:46036430..46036457,+p4@Apoa1


Enriched pathways on this co-expression cluster<b>Summary:</b><br>Canonical pathway gene sets were compiled from Reactome, Wikipathways and KEGG. For the major signaling pathways, the transcriptionally-regulated genes (downstream targets) were obtained from Netpath. Combined, the canonical pathways and downstream targets totaled 489 human gene sets. The corresponding M. musculus gene sets were inferred by homology using the HomoloGene database. Enrichment for each of the canonical 489 pathways and gene sets included in the co-expression cluster was assessed by the hypergeometric probability. The resulting P values were also then adjusted by the Benjamini-Hochberg method for multiple comparisons.<br><b>Analyst: </b>Emmanuel Dimont<br><br>link to source dataset<br>data

GO IDGO nameFDR corrected p-value
GO:0043534blood vessel endothelial cell migration0.0211130385121345
GO:0008035high-density lipoprotein binding0.0211130385121345
GO:0033344cholesterol efflux0.0211130385121345
GO:0030300regulation of cholesterol absorption0.0211130385121345
GO:0030299cholesterol absorption0.0211130385121345
GO:0044241lipid digestion0.0211130385121345
GO:0051346negative regulation of hydrolase activity0.0211130385121345
GO:0017127cholesterol transporter activity0.0211130385121345
GO:0043542endothelial cell migration0.0211130385121345
GO:0015248sterol transporter activity0.0211130385121345
GO:0001935endothelial cell proliferation0.0211130385121345
GO:0050892intestinal absorption0.0211130385121345
GO:0008211glucocorticoid metabolic process0.0211130385121345
GO:0030325adrenal gland development0.0211130385121345
GO:0019915sequestering of lipid0.021892603712342
GO:0008034lipoprotein binding0.025103850034829
GO:0022600digestive system process0.025103850034829
GO:0030301cholesterol transport0.0255301778494967
GO:0015918sterol transport0.0259112507101296
GO:0006695cholesterol biosynthetic process0.03607532601436
GO:0016126sterol biosynthetic process0.0452546430490102



Relative expression of the co-expression cluster over median <br>Analyst:




Enriched sample ontology terms on this co-expression cluster<b>Summary:</b>To summarize promoter activities (expression profile of a TSS region) across ~1000 samples, we performed enrichment analysis based on FANTOM5 Sample Ontology (FF ontology). The question here is “in which type of samples the promoter is more active”. To answer this question, we compared expressions (TPMs) in the samples associated with a sample ontology term and the rest of the samples by using the Mann-Whitney rank sum test. To summarize ontologies enriched in this co-expression cluster, we ran the same analysis on an averaged expression profile of all promoters that make up. <b>Analyst:</b> Hideya Kawaji <br><br>links to source dataset<br><br>cell_data<br>uberon_data<br><br>


TFBS overrepresentation<b>Summary:</b>The values shown are the p-values for overrepresentation of the motif in this coexpression cluster. So a small p-value means a strong overrepresentation. <b>Analyst:</b> Michiel de Hoon <br><br>link to source data <br> Novel motifs <br>data <br><br> Jaspar motifs <br>data

Novel motifs




JASPAR motifs


Motifs-log10(p-value)
MA0003.10.211284
MA0004.10.603793
MA0006.10.419915
MA0007.10.587678
MA0009.11.06266
MA0014.10.0502051
MA0017.11.14026
MA0019.10.874061
MA0024.11.01759
MA0025.11.30092
MA0027.12.72141
MA0028.10.43138
MA0029.10.995171
MA0030.11.00195
MA0031.10.965177
MA0038.10.757669
MA0040.11.07552
MA0041.10.522007
MA0042.10.507715
MA0043.11.1618
MA0046.11.09955
MA0048.10.205696
MA0050.10.645342
MA0051.10.767098
MA0052.11.08379
MA0055.10.0851423
MA0056.10
MA0057.10.192781
MA0058.10.50032
MA0059.10.513699
MA0060.10.881183
MA0061.10.955135
MA0063.10
MA0066.10.746072
MA0067.11.41352
MA0068.10.197245
MA0069.11.08414
MA0070.11.07418
MA0071.10.644448
MA0072.11.06547
MA0073.10.310158
MA0074.10.708108
MA0076.10.470037
MA0077.11.04318
MA0078.10.801834
MA0081.10.53877
MA0083.11.16099
MA0084.11.74401
MA0087.11.11687
MA0088.10.148348
MA0089.10
MA0090.10.566938
MA0091.10.617887
MA0092.10.567278
MA0093.10.440484
MA0095.10
MA0098.10
MA0100.10.695835
MA0101.10.523409
MA0103.11.16573
MA0105.11.98468
MA0106.10.809991
MA0107.10.454197
MA0108.20.897859
MA0109.10
MA0111.10.582193
MA0113.10.780358
MA0114.10.949408
MA0115.11.16466
MA0116.10.419688
MA0117.11.13165
MA0119.10.524046
MA0122.11.15196
MA0124.11.35963
MA0125.11.28445
MA0130.10
MA0131.10.869325
MA0132.10
MA0133.10
MA0135.11.19898
MA0136.10.729175
MA0139.10.295945
MA0140.10.695713
MA0141.10.482463
MA0142.10.950155
MA0143.10.797553
MA0144.10.956957
MA0145.10.476962
MA0146.10.21827
MA0147.10.378658
MA0148.10.621195
MA0149.10.529387
MA0062.20.254018
MA0035.20.700704
MA0039.20.749235
MA0138.20.861035
MA0002.20.299191
MA0137.20.479301
MA0104.20.315156
MA0047.20.75686
MA0112.20.927461
MA0065.20.929207
MA0150.10.587557
MA0151.10
MA0152.10.756973
MA0153.11.21594
MA0154.10.203217
MA0155.10.173445
MA0156.10.469089
MA0157.10.91689
MA0158.10
MA0159.11.01146
MA0160.11.51238
MA0161.10
MA0162.10.0699535
MA0163.10.230013
MA0164.10.729558
MA0080.20.455167
MA0018.20.739807
MA0099.20.854449
MA0079.20.435944
MA0102.21.79669
MA0258.10.346619
MA0259.10.366802
MA0442.10
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