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MCL coexpression mm9:3680: Difference between revisions

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{{MCL_coexpression_mm9
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chloride channel activity;0.0413509070568605;12725!GO:0022844;voltage-gated anion channel activity;0.0413509070568605;12725!GO:0016567;protein ubiquitination;0.0413509070568605;71538!GO:0000151;ubiquitin ligase complex;0.0413509070568605;71538!GO:0032446;protein modification by small protein conjugation;0.0413509070568605;71538!GO:0043168;anion binding;0.0413509070568605;12725!GO:0031404;chloride ion binding;0.0413509070568605;12725!GO:0005254;chloride channel activity;0.0413509070568605;12725!GO:0006821;chloride transport;0.0413509070568605;12725!GO:0005253;anion channel 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|gostat_on_MCL_coexpression=GO:0005247;voltage-gated chloride channel activity;0.0413509070568605;12725!GO:0022844;voltage-gated anion channel activity;0.0413509070568605;12725!GO:0016567;protein ubiquitination;0.0413509070568605;71538!GO:0000151;ubiquitin ligase complex;0.0413509070568605;71538!GO:0032446;protein modification by small protein conjugation;0.0413509070568605;71538!GO:0043168;anion binding;0.0413509070568605;12725!GO:0031404;chloride ion binding;0.0413509070568605;12725!GO:0005254;chloride channel activity;0.0413509070568605;12725!GO:0006821;chloride transport;0.0413509070568605;12725!GO:0005253;anion channel activity;0.0413509070568605;12725!
}}

Latest revision as of 20:29, 17 September 2013


Phase1 CAGE Peaks

 Short description
Mm9::chr8:63462012..63462116,-p1@Clcn3
Mm9::chr9:77956395..77956423,-p2@Fbxo9
Mm9::chr9:77956424..77956457,-p1@Fbxo9


Enriched pathways on this co-expression cluster<b>Summary:</b><br>Canonical pathway gene sets were compiled from Reactome, Wikipathways and KEGG. For the major signaling pathways, the transcriptionally-regulated genes (downstream targets) were obtained from Netpath. Combined, the canonical pathways and downstream targets totaled 489 human gene sets. The corresponding M. musculus gene sets were inferred by homology using the HomoloGene database. Enrichment for each of the canonical 489 pathways and gene sets included in the co-expression cluster was assessed by the hypergeometric probability. The resulting P values were also then adjusted by the Benjamini-Hochberg method for multiple comparisons.<br><b>Analyst: </b>Emmanuel Dimont<br><br>link to source dataset<br>data

GO IDGO nameFDR corrected p-value
GO:0005247voltage-gated chloride channel activity0.0413509070568605
GO:0022844voltage-gated anion channel activity0.0413509070568605
GO:0016567protein ubiquitination0.0413509070568605
GO:0000151ubiquitin ligase complex0.0413509070568605
GO:0032446protein modification by small protein conjugation0.0413509070568605
GO:0043168anion binding0.0413509070568605
GO:0031404chloride ion binding0.0413509070568605
GO:0005254chloride channel activity0.0413509070568605
GO:0006821chloride transport0.0413509070568605
GO:0005253anion channel activity0.0413509070568605



Relative expression of the co-expression cluster over median <br>Analyst:




Enriched sample ontology terms on this co-expression cluster<b>Summary:</b>To summarize promoter activities (expression profile of a TSS region) across ~1000 samples, we performed enrichment analysis based on FANTOM5 Sample Ontology (FF ontology). The question here is “in which type of samples the promoter is more active”. To answer this question, we compared expressions (TPMs) in the samples associated with a sample ontology term and the rest of the samples by using the Mann-Whitney rank sum test. To summarize ontologies enriched in this co-expression cluster, we ran the same analysis on an averaged expression profile of all promoters that make up. <b>Analyst:</b> Hideya Kawaji <br><br>links to source dataset<br><br><br>uberon_data<br><br>

Uber Anatomy
Ontology termp-valuen
anatomical conduit1.00e-09122
tube7.09e-09114
organ system subdivision1.03e-08194
regional part of nervous system1.07e-0854
exocrine gland1.95e-0825
exocrine system1.95e-0825
neural tube9.47e-0852
neural rod9.47e-0852
future spinal cord9.47e-0852
neural keel9.47e-0852
liver1.18e-0722
epithelial sac1.18e-0722
digestive gland1.18e-0722
epithelium of foregut-midgut junction1.18e-0722
anatomical boundary1.18e-0722
hepatobiliary system1.18e-0722
foregut-midgut junction1.18e-0722
hepatic diverticulum1.18e-0722
liver primordium1.18e-0722
septum transversum1.18e-0722
liver bud1.18e-0722
adult organism1.30e-0751
gray matter1.71e-0734
central nervous system1.98e-0773
digestive tract diverticulum2.20e-0723
sac2.20e-0723
occipital lobe6.32e-0710
visual cortex6.32e-0710
neocortex6.32e-0710


TFBS overrepresentation<b>Summary:</b>The values shown are the p-values for overrepresentation of the motif in this coexpression cluster. So a small p-value means a strong overrepresentation. <b>Analyst:</b> Michiel de Hoon <br><br>link to source data <br> Novel motifs <br>data <br><br> Jaspar motifs <br>data

Novel motifs




JASPAR motifs


Motifs-log10(p-value)
MA0003.10.0699972
MA0004.10.801718
MA0006.10.60285
MA0007.10.784593
MA0009.11.27673
MA0014.11.33691
MA0017.10.635031
MA0019.11.08369
MA0024.11.23079
MA0025.11.51835
MA0027.12.9431
MA0028.10.61552
MA0029.11.20789
MA0030.11.21482
MA0031.11.17722
MA0038.10.963265
MA0040.11.28983
MA0041.10.714279
MA0042.10.69885
MA0043.11.3775
MA0046.11.31428
MA0048.11.66457
MA0050.10.845669
MA0051.10.973068
MA0052.11.29825
MA0055.10.190475
MA0056.10
MA0057.10.337566
MA0058.10.690848
MA0059.10.705317
MA0060.10.502699
MA0061.10.5406
MA0063.10
MA0066.10.951196
MA0067.11.63197
MA0068.10.343188
MA0069.11.29861
MA0070.11.28847
MA0071.10.844726
MA0072.11.2796
MA0073.10.00834468
MA0074.10.911576
MA0076.10.657929
MA0077.11.2569
MA0078.11.0091
MA0081.10.732313
MA0083.11.37668
MA0084.11.96428
MA0087.11.33189
MA0088.10.27999
MA0089.10
MA0090.10.762482
MA0091.10.816659
MA0092.10.762845
MA0093.10.62555
MA0095.10
MA0098.10
MA0100.10.89873
MA0101.10.71579
MA0103.10.647985
MA0105.10.405648
MA0106.11.01755
MA0107.10.640607
MA0108.21.10817
MA0109.10
MA0111.10.778753
MA0113.10.986839
MA0114.10.537669
MA0115.11.38041
MA0116.10.602598
MA0117.11.34691
MA0119.12.86019
MA0122.11.36752
MA0124.11.57762
MA0125.11.5017
MA0130.10
MA0131.11.07881
MA0132.10
MA0133.10
MA0135.11.4152
MA0136.10.933582
MA0139.10.462282
MA0140.10.898603
MA0141.10.671467
MA0142.11.16183
MA0143.11.00467
MA0144.10.541532
MA0145.10.292366
MA0146.11.44443
MA0147.10.556853
MA0148.10.820161
MA0149.10.722227
MA0062.20.412742
MA0035.20.903829
MA0039.20.181475
MA0138.21.07027
MA0002.20.466067
MA0137.20.668025
MA0104.20.48458
MA0047.20.962424
MA0112.20.29236
MA0065.20.292912
MA0150.10.784464
MA0151.10
MA0152.10.962542
MA0153.11.43238
MA0154.10.925147
MA0155.10.312898
MA0156.10.656895
MA0157.11.12772
MA0158.10
MA0159.10.569393
MA0160.10.823568
MA0161.10
MA0162.10.499274
MA0163.10.157796
MA0164.10.933981
MA0080.20.64167
MA0018.22.17326
MA0099.21.06348
MA0079.20.00937321
MA0102.22.01714
MA0258.10.520639
MA0259.10.543506
MA0442.10
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