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{{CL
{{CL
|id=CL:0000216
|alt_id=
|name=Sertoli cell
|namespace=cell;;efo
|def="A supporting cell projecting inward from the basement membrane of seminiferous tubules. They surround and nourish the developing male germ cells and secrete androgen binding protein. Their tight junctions with the spermatogonia and spermatocytes provide a blood-testis barrier." [MESH:A.05.360.444.849.789]
|xref=BTO:0001238;;FMA:72298
|is_a=CL:0000511;;CL:0000630;;CL:0002625;;EFO:0000984;;EFO:0002962
|synonym=
|comment=
|comment=
|alt_id=
|disjoint_from=
|union_of=
|created_by=
|created_by=
|obo_creation_date=
|def="A supporting cell projecting inward from the basement membrane of seminiferous tubules. They surround and nourish the developing male germ cells and secrete androgen binding protein. Their tight junctions with the spermatogonia and spermatocytes provide a blood-testis barrier." [MESH:A.05.360.444.849.789]
|subset=
|derives_from=
|derives_from=
|develops_from=
|develops_from=
|disjoint_from=
|has_quality=
|has_quality=
|id=CL:0000216
|is_a=CL:0000511 ;;CL:0000630 ;;CL:0002625
|is_obsolete=
|located_in=
|located_in=
|part_of=UBERON:0000473
|name=Sertoli cell
|namespace=cell;;efo
|obo_creation_date=
|part_of=UBERON:0001343
|preceded_by=
|property_value=IAO:0000412 http://purl.obolibrary.org/obo/cl-to-uberon.owl;;IAO:0000412 http://purl.obolibrary.org/obo/cl.owl;;IAO:0000412 http://purl.obolibrary.org/obo/efo.owl
|property_value=IAO:0000412 http://purl.obolibrary.org/obo/cl-to-uberon.owl;;IAO:0000412 http://purl.obolibrary.org/obo/cl.owl;;IAO:0000412 http://purl.obolibrary.org/obo/efo.owl
|is_obsolete=
|subset=
|preceded_by=
|synonym=
|union_of=
|xref=BTO:0001238;;FMA:72298
}}
}}

Revision as of 10:15, 12 September 2014

Name:Sertoli cell
Namespace:cell;;efo
Definition:"A supporting cell projecting inward from the basement membrane of seminiferous tubules. They surround and nourish the developing male germ cells and secrete androgen binding protein. Their tight junctions with the spermatogonia and spermatocytes provide a blood-testis barrier." [MESH:A.05.360.444.849.789]
Xrefs:
links:

BTO:0001238

FMA:72298


Ontology association <br>Each term has an is_a parent in the Cell ontology, which has a linkage to an another entity and FANTOM5 samples.Libraries were grouped into mutually exclusive facets according to the FANTOM5 sample ontology mapping to Cell ontologies.<br><br>link to ontology dataset<br>data

Parents

is_a:CL:0000511(androgen binding protein secreting cell),CL:0000630(supportive cell),CL:0002625(seminiferous tubule epithelial cell)
part_of:UBERON:0001343(seminiferous tubule of testis)



Children


derives from:FF:0000161 (human sertoli cell sample)

Ontology Tree: Loaded from BioPortal

Ontorolgy tree(Small window open)


FF samples<br>It includes FANTOM5 samples that overlay the Cell ontology.

Human (Homo sapiens)

Mouse (Mus musculus)


Enrichment analysis: top 100 FFCP enriched with this ontology termTOP 100 FANTOM5 Cage Peaks enriched with CL:0000216 (Sertoli cell), sorted by p-values <br>Analyst: Hideya Kawaji<br><br>link to source dataset <br>human : data <br>mouse : data

P-valueFFCPShort description
5.42e-195FFCP PHASE1:Hg19::chr11:27721743..27721753,-#_7ffaf29c669acb8f627b9ab4e9f59ff3p26@BDNF
5.42e-195FFCP PHASE2:Hg19::chr11:27721743..27721753,-#_7ffaf29c669acb8f627b9ab4e9f59ff3p26@BDNF
9.37e-99FFCP PHASE1:Hg19::chr1:227505905..227505906,-#_9c44467c7b4c2d0984d0074c240117fcp43@CDC42BPA
9.37e-99FFCP PHASE1:Hg19::chr3:158450428..158450431,-#_9c44467c7b4c2d0984d0074c240117fcp9@RARRES1
9.37e-99FFCP PHASE2:Hg19::chr3:158450428..158450431,-#_9c44467c7b4c2d0984d0074c240117fcp9@RARRES1
9.37e-99FFCP PHASE2:Hg19::chr1:227505905..227505906,-#_9c44467c7b4c2d0984d0074c240117fcp43@CDC42BPA
2.55e-98FFCP PHASE2:Hg19::chr8:69832864..69832865,+#_be5d8bde80c8ad8592056c4d8ae7c74ep@chr8:69832864..69832865, +
2.55e-98FFCP PHASE2:Hg19::chr13:53030077..53030083,-#_be5d8bde80c8ad8592056c4d8ae7c74ep@chr13:53030077..53030083, -
2.55e-98FFCP PHASE2:Hg19::chr7:18206831..18206833,+#_be5d8bde80c8ad8592056c4d8ae7c74ep@chr7:18206831..18206833, +
2.55e-98FFCP PHASE1:Hg19::chr8:47529304..47529311,-#_be5d8bde80c8ad8592056c4d8ae7c74ep@chr8:47529304..47529311, -
2.55e-98FFCP PHASE2:Hg19::chr2:9519086..9519101,+#_be5d8bde80c8ad8592056c4d8ae7c74ep@chr2:9519086..9519101, +
2.55e-98FFCP PHASE2:Hg19::chr3:193356854..193356864,+#_be5d8bde80c8ad8592056c4d8ae7c74ep@chr3:193356854..193356864, +
2.55e-98FFCP PHASE2:Hg19::chr3:170430340..170430344,+#_be5d8bde80c8ad8592056c4d8ae7c74ep@chr3:170430340..170430344, +
2.55e-98FFCP PHASE2:Hg19::chr19:54600897..54600899,+#_be5d8bde80c8ad8592056c4d8ae7c74ep@chr19:54600897..54600899, +
2.55e-98FFCP PHASE2:Hg19::chr7:89874193..89874199,+#_be5d8bde80c8ad8592056c4d8ae7c74ep7@C7orf63
2.55e-98FFCP PHASE1:Hg19::chr8:69832864..69832865,+#_be5d8bde80c8ad8592056c4d8ae7c74ep@chr8:69832864..69832865, +
2.55e-98FFCP PHASE2:Hg19::chr19:40320572..40320586,-#_be5d8bde80c8ad8592056c4d8ae7c74ep@chr19:40320572..40320586, -
2.55e-98FFCP PHASE1:Hg19::chr19:54600897..54600899,+#_be5d8bde80c8ad8592056c4d8ae7c74ep@chr19:54600897..54600899, +
2.55e-98FFCP PHASE1:Hg19::chr19:40320572..40320586,-#_be5d8bde80c8ad8592056c4d8ae7c74ep@chr19:40320572..40320586, -
2.55e-98FFCP PHASE1:Hg19::chr13:53030077..53030083,-#_be5d8bde80c8ad8592056c4d8ae7c74ep@chr13:53030077..53030083, -
2.55e-98FFCP PHASE2:Hg19::chr8:47529304..47529311,-#_be5d8bde80c8ad8592056c4d8ae7c74ep@chr8:47529304..47529311, -
2.55e-98FFCP PHASE1:Hg19::chr7:18206831..18206833,+#_be5d8bde80c8ad8592056c4d8ae7c74ep@chr7:18206831..18206833, +
2.55e-98FFCP PHASE1:Hg19::chr3:193356854..193356864,+#_be5d8bde80c8ad8592056c4d8ae7c74ep@chr3:193356854..193356864, +
2.55e-98FFCP PHASE1:Hg19::chr3:170430340..170430344,+#_be5d8bde80c8ad8592056c4d8ae7c74ep@chr3:170430340..170430344, +
2.55e-98FFCP PHASE1:Hg19::chr2:9519086..9519101,+#_be5d8bde80c8ad8592056c4d8ae7c74ep@chr2:9519086..9519101, +
2.55e-98FFCP PHASE1:Hg19::chr7:89874193..89874199,+#_be5d8bde80c8ad8592056c4d8ae7c74ep7@C7orf63
1.23e-66FFCP PHASE2:Hg19::chr2:19551668..19551679,-#_72058c6c6020c2e61683b6cfbe3719acp@chr2:19551668..19551679, -
1.23e-66FFCP PHASE1:Hg19::chr2:19551668..19551679,-#_72058c6c6020c2e61683b6cfbe3719acp@chr2:19551668..19551679, -
2.39e-66FFCP PHASE2:Hg19::chr7:98445585..98445594,-#_c3e9baf02264df170bf747a717fc9416p22@TMEM130
2.39e-66FFCP PHASE2:Hg19::chr2:72803155..72803204,-#_c3e9baf02264df170bf747a717fc9416p@chr2:72803155..72803204, -
2.39e-66FFCP PHASE1:Hg19::chr3:112931461..112931474,-#_c3e9baf02264df170bf747a717fc9416p@chr3:112931461..112931474, -
2.39e-66FFCP PHASE1:Hg19::chr7:98445585..98445594,-#_c3e9baf02264df170bf747a717fc9416p22@TMEM130
2.39e-66FFCP PHASE2:Hg19::chr1:197889533..197889548,+#_c3e9baf02264df170bf747a717fc9416p@chr1:197889533..197889548, +
2.39e-66FFCP PHASE1:Hg19::chr1:197889533..197889548,+#_c3e9baf02264df170bf747a717fc9416p@chr1:197889533..197889548, +
2.39e-66FFCP PHASE1:Hg19::chr12:15815732..15815744,-#_c3e9baf02264df170bf747a717fc9416p21@EPS8
2.39e-66FFCP PHASE2:Hg19::chr3:112931461..112931474,-#_c3e9baf02264df170bf747a717fc9416p@chr3:112931461..112931474, -
2.39e-66FFCP PHASE2:Hg19::chr12:15815732..15815744,-#_c3e9baf02264df170bf747a717fc9416p21@EPS8
2.39e-66FFCP PHASE1:Hg19::chr2:72803155..72803204,-#_c3e9baf02264df170bf747a717fc9416p@chr2:72803155..72803204, -
4.66e-66FFCP PHASE2:Hg19::chr3:170916991..170916995,-#_becda03344b0f13264ad788962ee5e62p@chr3:170916991..170916995, -
4.66e-66FFCP PHASE1:Hg19::chr5:90830481..90830492,+#_becda03344b0f13264ad788962ee5e62p@chr5:90830481..90830492, +
4.66e-66FFCP PHASE2:Hg19::chr8:141728731..141728740,-#_becda03344b0f13264ad788962ee5e62p38@PTK2
4.66e-66FFCP PHASE2:Hg19::chr5:75912402..75912418,-#_becda03344b0f13264ad788962ee5e62p@chr5:75912402..75912418, -
4.66e-66FFCP PHASE2:Hg19::chr21:48080873..48080878,+#_becda03344b0f13264ad788962ee5e62p@chr21:48080873..48080878, +
4.66e-66FFCP PHASE2:Hg19::chr3:99984127..99984138,+#_becda03344b0f13264ad788962ee5e62p@chr3:99984127..99984138, +
4.66e-66FFCP PHASE1:Hg19::chr3:170916991..170916995,-#_becda03344b0f13264ad788962ee5e62p@chr3:170916991..170916995, -
4.66e-66FFCP PHASE1:Hg19::chr21:48080873..48080878,+#_becda03344b0f13264ad788962ee5e62p@chr21:48080873..48080878, +
4.66e-66FFCP PHASE1:Hg19::chr10:1034666..1034675,+#_becda03344b0f13264ad788962ee5e62p4@GTPBP4
4.66e-66FFCP PHASE2:Hg19::chr5:90830481..90830492,+#_becda03344b0f13264ad788962ee5e62p@chr5:90830481..90830492, +
4.66e-66FFCP PHASE2:Hg19::chr10:1034666..1034675,+#_becda03344b0f13264ad788962ee5e62p4@GTPBP4
4.66e-66FFCP PHASE1:Hg19::chr8:141728731..141728740,-#_becda03344b0f13264ad788962ee5e62p38@PTK2
4.66e-66FFCP PHASE1:Hg19::chr5:75912402..75912418,-#_becda03344b0f13264ad788962ee5e62p@chr5:75912402..75912418, -
4.66e-66FFCP PHASE1:Hg19::chr3:99984127..99984138,+#_becda03344b0f13264ad788962ee5e62p@chr3:99984127..99984138, +
1.46e-50FFCP PHASE2:Hg19::chr2:177009137..177009140,+#_9b1a35c3254f8e0b9c27612eafcc0452p@chr2:177009137..177009140, +
1.46e-50FFCP PHASE1:Hg19::chr6:134210772..134210782,+#_9b1a35c3254f8e0b9c27612eafcc0452p8@TCF21
1.46e-50FFCP PHASE1:Hg19::chr11:114173606..114173612,+#_9b1a35c3254f8e0b9c27612eafcc0452p@chr11:114173606..114173612, +
1.46e-50FFCP PHASE2:Hg19::chr11:114173606..114173612,+#_9b1a35c3254f8e0b9c27612eafcc0452p@chr11:114173606..114173612, +
1.46e-50FFCP PHASE1:Hg19::chr2:177009137..177009140,+#_9b1a35c3254f8e0b9c27612eafcc0452p@chr2:177009137..177009140, +
1.46e-50FFCP PHASE2:Hg19::chr6:134210772..134210782,+#_9b1a35c3254f8e0b9c27612eafcc0452p8@TCF21
2.42e-50FFCP PHASE1:Hg19::chr5:144875561..144875565,+#_9e08c230f4ef1bc6f190f29380dc41b1p@chr5:144875561..144875565, +
2.42e-50FFCP PHASE1:Hg19::chr3:46477553..46477563,-#_9e08c230f4ef1bc6f190f29380dc41b1p@chr3:46477553..46477563, -
2.42e-50FFCP PHASE2:Hg19::chr21:17214724..17214740,+#_9e08c230f4ef1bc6f190f29380dc41b1p11@USP25
2.42e-50FFCP PHASE1:Hg19::chr7:137564648..137564658,-#_9e08c230f4ef1bc6f190f29380dc41b1p32@CREB3L2
2.42e-50FFCP PHASE1:Hg19::chr19:54024454..54024463,+#_9e08c230f4ef1bc6f190f29380dc41b1p31@ZNF331
2.42e-50FFCP PHASE1:Hg19::chr21:17214724..17214740,+#_9e08c230f4ef1bc6f190f29380dc41b1p11@USP25
2.42e-50FFCP PHASE1:Hg19::chr2:55459485..55459491,-#_9e08c230f4ef1bc6f190f29380dc41b1p6@C2orf63
2.42e-50FFCP PHASE2:Hg19::chr5:144875561..144875565,+#_9e08c230f4ef1bc6f190f29380dc41b1p@chr5:144875561..144875565, +
2.42e-50FFCP PHASE2:Hg19::chr7:137564648..137564658,-#_9e08c230f4ef1bc6f190f29380dc41b1p32@CREB3L2
2.42e-50FFCP PHASE2:Hg19::chr15:39288691..39288698,+#_9e08c230f4ef1bc6f190f29380dc41b1p@chr15:39288691..39288698, +
2.42e-50FFCP PHASE2:Hg19::chr3:46477553..46477563,-#_9e08c230f4ef1bc6f190f29380dc41b1p@chr3:46477553..46477563, -
2.42e-50FFCP PHASE2:Hg19::chr2:55459485..55459491,-#_9e08c230f4ef1bc6f190f29380dc41b1p6@C2orf63
2.42e-50FFCP PHASE2:Hg19::chr19:54024454..54024463,+#_9e08c230f4ef1bc6f190f29380dc41b1p31@ZNF331
2.42e-50FFCP PHASE1:Hg19::chr15:39288691..39288698,+#_9e08c230f4ef1bc6f190f29380dc41b1p@chr15:39288691..39288698, +
3.99e-50FFCP PHASE2:Hg19::chr11:829412..829430,+#_75cec8f13532dbd064f08f04d8a5152ap11@EFCAB4A
3.99e-50FFCP PHASE2:Hg19::chr4:103969123..103969127,-#_75cec8f13532dbd064f08f04d8a5152ap@chr4:103969123..103969127, -
3.99e-50FFCP PHASE1:Hg19::chr14:64804787..64804796,-#_75cec8f13532dbd064f08f04d8a5152ap10@ESR2
3.99e-50FFCP PHASE1:Hg19::chr15:39420650..39420666,+#_75cec8f13532dbd064f08f04d8a5152ap@chr15:39420650..39420666, +
3.99e-50FFCP PHASE1:Hg19::chr12:5198350..5198359,+#_75cec8f13532dbd064f08f04d8a5152ap@chr12:5198350..5198359, +
3.99e-50FFCP PHASE1:Hg19::chr4:103969123..103969127,-#_75cec8f13532dbd064f08f04d8a5152ap@chr4:103969123..103969127, -
3.99e-50FFCP PHASE1:Hg19::chr11:829412..829430,+#_75cec8f13532dbd064f08f04d8a5152ap11@EFCAB4A
3.99e-50FFCP PHASE2:Hg19::chr12:5198350..5198359,+#_75cec8f13532dbd064f08f04d8a5152ap@chr12:5198350..5198359, +
3.99e-50FFCP PHASE2:Hg19::chr14:64804787..64804796,-#_75cec8f13532dbd064f08f04d8a5152ap10@ESR2
3.99e-50FFCP PHASE2:Hg19::chr15:39420650..39420666,+#_75cec8f13532dbd064f08f04d8a5152ap@chr15:39420650..39420666, +
6.58e-50FFCP PHASE1:Hg19::chr17:58165788..58165794,-#_a74cb353c1ae0b31063f7e6e619ca130p1@LOC645638
6.58e-50FFCP PHASE2:Hg19::chr14:50697797..50697820,-#_a74cb353c1ae0b31063f7e6e619ca130p13@SOS2
6.58e-50FFCP PHASE1:Hg19::chr16:1203194..1203207,+#_a74cb353c1ae0b31063f7e6e619ca130p3@CACNA1H
6.58e-50FFCP PHASE2:Hg19::chr17:58165788..58165794,-#_a74cb353c1ae0b31063f7e6e619ca130p1@LOC645638
6.58e-50FFCP PHASE1:Hg19::chr7:92462738..92462749,-#_a74cb353c1ae0b31063f7e6e619ca130p51@CDK6
6.58e-50FFCP PHASE2:Hg19::chr16:1203194..1203207,+#_a74cb353c1ae0b31063f7e6e619ca130p3@CACNA1H
6.58e-50FFCP PHASE1:Hg19::chr14:50697797..50697820,-#_a74cb353c1ae0b31063f7e6e619ca130p13@SOS2
6.58e-50FFCP PHASE2:Hg19::chr7:92462738..92462749,-#_a74cb353c1ae0b31063f7e6e619ca130p51@CDK6
6.62e-41FFCP PHASE1:Hg19::chr3:194214959..194214968,-#_08bc211c76f5bf498967d83b19cde4d7p@chr3:194214959..194214968, -
6.62e-41FFCP PHASE2:Hg19::chr3:194214959..194214968,-#_08bc211c76f5bf498967d83b19cde4d7p@chr3:194214959..194214968, -
9.91e-41FFCP PHASE2:Hg19::chr11:110581726..110581728,-#_5f578c6d835d5b2bf75506d82088a9e4p@chr11:110581726..110581728, -
9.91e-41FFCP PHASE1:Hg19::chr13:49549473..49549480,+#_5f578c6d835d5b2bf75506d82088a9e4p@chr13:49549473..49549480, +
9.91e-41FFCP PHASE1:Hg19::chr15:34522001..34522013,+#_5f578c6d835d5b2bf75506d82088a9e4p@chr15:34522001..34522013, +
9.91e-41FFCP PHASE2:Hg19::chr2:102604493..102604499,+#_5f578c6d835d5b2bf75506d82088a9e4p@chr2:102604493..102604499, +
9.91e-41FFCP PHASE1:Hg19::chr11:77282391..77282402,+#_5f578c6d835d5b2bf75506d82088a9e4p@chr11:77282391..77282402, +
9.91e-41FFCP PHASE2:Hg19::chr8:125193673..125193689,-#_5f578c6d835d5b2bf75506d82088a9e4p@chr8:125193673..125193689, -
9.91e-41FFCP PHASE2:Hg19::chr3:49139102..49139119,-#_5f578c6d835d5b2bf75506d82088a9e4p@chr3:49139102..49139119, -
9.91e-41FFCP PHASE1:Hg19::chr11:94822746..94822757,+#_5f578c6d835d5b2bf75506d82088a9e4p8@ENDOD1

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