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{{CL
{{CL
|id=CL:0000051
|alt_id=CL:0000044
|name=common lymphoid progenitor
|namespace=cell;;efo
|def="A oligopotent progenitor cell committed to the lymphoid lineage." [GOC:add, GOC:dsd, GOC:tfm, PMID:10407577, PMID:16551251]
|xref=
|is_a=CL:0002032
|synonym="CLP" EXACT [];;"committed lymphopoietic stem cell" RELATED [];;"common lymphocyte precursor" EXACT [];;"common lymphocyte progenitor" EXACT [];;"common lymphoid precursor" EXACT [];;"early lymphocyte progenitor" RELATED [];;"ELP" RELATED [];;"lymphoid stem cell" RELATED [];;"lymphopoietic stem cell" RELATED []
|comment=CLP are CD7-positive, CD10-positive, CD19-negative, CD34-positive, CD45RA-positive, CD79a-negative, CD127-positive, AA4.1-positive, RAG-negative, Sca-1-low, sIgM-negative, sIgD-negative, TdT-negative, Vpre-B-negative, and pre-BCR-negative. Expression of transcription factors include E2A-positive, EBF-positive, Ikaros-negative, PU.1-negative, and Pax5-negative.
|comment=CLP are CD7-positive, CD10-positive, CD19-negative, CD34-positive, CD45RA-positive, CD79a-negative, CD127-positive, AA4.1-positive, RAG-negative, Sca-1-low, sIgM-negative, sIgD-negative, TdT-negative, Vpre-B-negative, and pre-BCR-negative. Expression of transcription factors include E2A-positive, EBF-positive, Ikaros-negative, PU.1-negative, and Pax5-negative.
|alt_id=CL:0000044
|disjoint_from=
|union_of=
|created_by=
|created_by=
|obo_creation_date=
|def="A oligopotent progenitor cell committed to the lymphoid lineage." [GOC:add, GOC:dsd, GOC:tfm, PMID:10407577, PMID:16551251]
|subset=
|derives_from=
|derives_from=
|develops_from=
|develops_from=
|disjoint_from=
|has_quality=
|has_quality=
|id=CL:0000051
|is_a=CL:0002032
|is_obsolete=
|located_in=
|located_in=
|name=common lymphoid progenitor
|namespace=FANTOM
|obo_creation_date=
|part_of=
|part_of=
|preceded_by=
|property_value=IAO:0000412 http://purl.obolibrary.org/obo/cl.owl;;IAO:0000412 http://purl.obolibrary.org/obo/efo.owl
|property_value=IAO:0000412 http://purl.obolibrary.org/obo/cl.owl;;IAO:0000412 http://purl.obolibrary.org/obo/efo.owl
|is_obsolete=
|subset=
|preceded_by=
|synonym="CLP" EXACT [];;"committed lymphopoietic stem cell" RELATED [];;"common lymphocyte precursor" EXACT [];;"common lymphocyte progenitor" EXACT [];;"common lymphoid precursor" EXACT [];;"early lymphocyte progenitor" RELATED [];;"ELP" RELATED [];;"lymphoid stem cell" RELATED [];;"lymphopoietic stem cell" RELATED []
|union_of=
|xref=
}}
}}

Latest revision as of 16:28, 12 September 2014

Name:common lymphoid progenitor
Namespace:FANTOM
Definition:"A oligopotent progenitor cell committed to the lymphoid lineage." [GOC:add, GOC:dsd, GOC:tfm, PMID:10407577, PMID:16551251]
Synonyms: "CLP" EXACT []
"committed lymphopoietic stem cell" RELATED []
"common lymphocyte precursor" EXACT []
"common lymphocyte progenitor" EXACT []
"common lymphoid precursor" EXACT []
"early lymphocyte progenitor" RELATED []
"ELP" RELATED []
"lymphoid stem cell" RELATED []
"lymphopoietic stem cell" RELATED []
Comments:CLP are CD7-positive, CD10-positive, CD19-negative, CD34-positive, CD45RA-positive, CD79a-negative, CD127-positive, AA4.1-positive, RAG-negative, Sca-1-low, sIgM-negative, sIgD-negative, TdT-negative, Vpre-B-negative, and pre-BCR-negative. Expression of transcription factors include E2A-positive, EBF-positive, Ikaros-negative, PU.1-negative, and Pax5-negative.
Alt_id: CL:0000044


Ontology association <br>Each term has an is_a parent in the Cell ontology, which has a linkage to an another entity and FANTOM5 samples.Libraries were grouped into mutually exclusive facets according to the FANTOM5 sample ontology mapping to Cell ontologies.<br><br>link to ontology dataset<br>data

Parents

is_a:CL:0002032(hematopoietic oligopotent progenitor cell)



Children


disjoint from:CL:0000049 (common myeloid progenitor)
develops from:CL:0000542 (lymphocyte),CL:0000825 (pro-NK cell),CL:0000826 (pro-B cell),CL:0000827 (pro-T cell)

Ontology Tree: Loaded from BioPortal

Ontorolgy tree(Small window open)


FF samples<br>It includes FANTOM5 samples that overlay the Cell ontology.



Enrichment analysis: top 100 FFCP enriched with this ontology termTOP 100 FANTOM5 Cage Peaks enriched with CL:0000051 (common lymphoid progenitor), sorted by p-values <br>Analyst: Hideya Kawaji<br><br>link to source dataset <br>human : data <br>mouse : data

P-valueFFCPShort description
2.13e-82FFCP PHASE2:Hg19::chr5:150521260..150521277,-#_12273b98a1733528fe967a17c35b8d6ep5@ANXA6
2.13e-82FFCP PHASE1:Hg19::chr5:150521260..150521277,-#_12273b98a1733528fe967a17c35b8d6ep5@ANXA6
3.17e-82FFCP PHASE2:Hg19::chr11:67206142..67206156,-#_9871f788cee925c362976be782eccf93p@chr11:67206142..67206156, -
3.17e-82FFCP PHASE1:Hg19::chr11:67206142..67206156,-#_9871f788cee925c362976be782eccf93p@chr11:67206142..67206156, -
6.87e-78FFCP PHASE1:Hg19::chr12:9822355..9822366,+#_90c63f745b2fc35da8f8635a49c47e9cp3@CLEC2D
6.87e-78FFCP PHASE2:Hg19::chr12:9822355..9822366,+#_90c63f745b2fc35da8f8635a49c47e9cp3@CLEC2D
8.78e-77FFCP PHASE2:Hg19::chr9:35650572..35650659,-#_b1400c8440a631e060b0d4937fa83bbap2@SIT1
8.78e-77FFCP PHASE1:Hg19::chr9:35650572..35650659,-#_b1400c8440a631e060b0d4937fa83bbap2@SIT1
1.12e-76FFCP PHASE2:Hg19::chr9:140356580..140356585,+#_5b193074986188dfc21b599ca885e7bdp@chr9:140356580..140356585, +
1.12e-76FFCP PHASE1:Hg19::chr9:140356580..140356585,+#_5b193074986188dfc21b599ca885e7bdp@chr9:140356580..140356585, +
9.3e-76FFCP PHASE1:Hg19::chr17:37934188..37934202,-#_a42511396c462029edf5a3c3d03c2f00p8@IKZF3
9.3e-76FFCP PHASE2:Hg19::chr17:37934188..37934202,-#_a42511396c462029edf5a3c3d03c2f00p8@IKZF3
1.29e-75FFCP PHASE2:Hg19::chr11:118754537..118754552,+#_944a418b9ec8bfafd80274d37b90d60dp3@CXCR5
1.29e-75FFCP PHASE1:Hg19::chr11:118754537..118754552,+#_944a418b9ec8bfafd80274d37b90d60dp3@CXCR5
1.3e-75FFCP PHASE2:Hg19::chr17:38020481..38020506,-#_091cdf7e5aa9f32da0ef8c53cc906abdp7@IKZF3
1.3e-75FFCP PHASE1:Hg19::chr17:38020481..38020506,-#_091cdf7e5aa9f32da0ef8c53cc906abdp7@IKZF3
2.49e-75FFCP PHASE1:Hg19::chr1:207096529..207096554,-#_0651a8680660a94e0fca5d1bbb944c74p5@FAIM3
2.49e-75FFCP PHASE2:Hg19::chr1:207096529..207096554,-#_0651a8680660a94e0fca5d1bbb944c74p5@FAIM3
7.9e-73FFCP PHASE2:Hg19::chr1:27953007..27953025,-#_f6328af2e01596a86224dabd4894a19cp12@FGR
7.9e-73FFCP PHASE1:Hg19::chr1:27953007..27953025,-#_f6328af2e01596a86224dabd4894a19cp12@FGR
7.87e-72FFCP PHASE1:Hg19::chr6:31540403..31540430,-#_0d9a92e6ac4630421a2b3194c09f436ap1@LOC100287329
7.87e-72FFCP PHASE2:Hg19::chr6:31540403..31540430,-#_0d9a92e6ac4630421a2b3194c09f436ap1@LOC100287329
2.14e-71FFCP PHASE1:Hg19::chr14:20811696..20811707,+#_31d9387bfbe031ad80d3c91fbd6f63bfp4@PARP2
2.14e-71FFCP PHASE2:Hg19::chr14:20811696..20811707,+#_31d9387bfbe031ad80d3c91fbd6f63bfp4@PARP2
2.73e-71FFCP PHASE1:Hg19::chr17:38020607..38020621,-#_042476cde7ec12d7b07c68570e677bd0p9@IKZF3
2.73e-71FFCP PHASE2:Hg19::chr17:38020607..38020621,-#_042476cde7ec12d7b07c68570e677bd0p9@IKZF3
5.67e-71FFCP PHASE1:Hg19::chr8:71564073..71564104,+#_267ce9af9d0364bac16bb8830154c11bp@chr8:71564073..71564104, +
5.67e-71FFCP PHASE2:Hg19::chr8:71564073..71564104,+#_267ce9af9d0364bac16bb8830154c11bp@chr8:71564073..71564104, +
1.15e-70FFCP PHASE2:Hg19::chr11:64107589..64107604,-#_5f0895b225b7cc30ace8adf6e054be3bp@chr11:64107589..64107604, -
1.15e-70FFCP PHASE1:Hg19::chr11:64107589..64107604,-#_5f0895b225b7cc30ace8adf6e054be3bp@chr11:64107589..64107604, -
1.75e-70FFCP PHASE2:Hg19::chr17:37934204..37934241,-#_ea2bbd8217c0a5a85d68a2ce831ce734p3@IKZF3
1.75e-70FFCP PHASE1:Hg19::chr17:37934204..37934241,-#_ea2bbd8217c0a5a85d68a2ce831ce734p3@IKZF3
5.83e-70FFCP PHASE2:Hg19::chr3:107844539..107844555,-#_9176c5e37bfce914b95fd9f3d513ebbbp@chr3:107844539..107844555, -
5.83e-70FFCP PHASE1:Hg19::chr3:107844539..107844555,-#_9176c5e37bfce914b95fd9f3d513ebbbp@chr3:107844539..107844555, -
6.85e-70FFCP PHASE1:Hg19::chr14:23000807..23000874,+#_88cb65d9e8457c329d2e17ce1ff3798ap1@TRAJ12
6.85e-70FFCP PHASE2:Hg19::chr14:23000807..23000874,+#_88cb65d9e8457c329d2e17ce1ff3798ap1@TRAJ12
9.9e-70FFCP PHASE2:Hg19::chr11:111224819..111224845,+#_6be8f1895456268501e4991ebfbce540p2@CU689419
9.9e-70FFCP PHASE1:Hg19::chr11:111224819..111224845,+#_6be8f1895456268501e4991ebfbce540p2@CU689419
2.85e-69FFCP PHASE1:Hg19::chr17:38020557..38020572,-#_769368fcd1fa10c7346e16af4bdbc41fp4@IKZF3
2.85e-69FFCP PHASE2:Hg19::chr17:38020557..38020572,-#_769368fcd1fa10c7346e16af4bdbc41fp4@IKZF3
3.14e-69FFCP PHASE2:Hg19::chr5:150521234..150521251,-#_87bd3b67701db323c3737fee58a30b00p4@ANXA6
3.14e-69FFCP PHASE1:Hg19::chr5:150521234..150521251,-#_87bd3b67701db323c3737fee58a30b00p4@ANXA6
5.7e-69FFCP PHASE1:Hg19::chr19:39108644..39108658,-#_af6a9c24fafc7e4d4932f7b4ca8fe137p2@MAP4K1
5.7e-69FFCP PHASE2:Hg19::chr19:39108644..39108658,-#_af6a9c24fafc7e4d4932f7b4ca8fe137p2@MAP4K1
1.0e-68FFCP PHASE2:Hg19::chr17:38020516..38020544,-#_5e335da75e465498ff8b7e25ce40315dp5@IKZF3
1.0e-68FFCP PHASE1:Hg19::chr17:38020516..38020544,-#_5e335da75e465498ff8b7e25ce40315dp5@IKZF3
2.01e-68FFCP PHASE1:Hg19::chr1:207096678..207096699,+#_d5d6d87784db40944bb0bf989ed5fc46p@chr1:207096678..207096699, +
2.01e-68FFCP PHASE2:Hg19::chr1:207096678..207096699,+#_d5d6d87784db40944bb0bf989ed5fc46p@chr1:207096678..207096699, +
8.76e-68FFCP PHASE2:Hg19::chr7:50348268..50348366,+#_7928539f173b95102bafe18635529c83p4@IKZF1
8.76e-68FFCP PHASE1:Hg19::chr7:50348268..50348366,+#_7928539f173b95102bafe18635529c83p4@IKZF1
1.11e-67FFCP PHASE2:Hg19::chr11:67203630..67203643,-#_a684453f2a5e6fedd67af866e5fe764dp2@PTPRCAP
1.11e-67FFCP PHASE1:Hg19::chr11:67203630..67203643,-#_a684453f2a5e6fedd67af866e5fe764dp2@PTPRCAP
2.67e-67FFCP PHASE2:Mm9::chr4:32335511..32335532,+#_85dab843ac32c8dcd7cb1b008a7baae1p@chr4:32335511..32335532, +
2.67e-67FFCP PHASE1:Mm9::chr4:32335511..32335532,+#_85dab843ac32c8dcd7cb1b008a7baae1p@chr4:32335511..32335532, +
8.25e-67FFCP PHASE2:Hg19::chr13:30951074..30951122,-#_8396ae5124cea8d360d67b97f93d72c4p1@LINC00426
8.25e-67FFCP PHASE1:Hg19::chr13:30951074..30951122,-#_8396ae5124cea8d360d67b97f93d72c4p1@LINC00426
8.97e-67FFCP PHASE2:Hg19::chr18:60825437..60825471,-#_cd3f2f5f8bc8a668dc56b660e910137ap@chr18:60825437..60825471, -
8.97e-67FFCP PHASE1:Hg19::chr18:60825437..60825471,-#_cd3f2f5f8bc8a668dc56b660e910137ap@chr18:60825437..60825471, -
1.18e-66FFCP PHASE1:Hg19::chr8:28747682..28747705,-#_e22c587125abd623130560e8476a51e0p2@INTS9
1.18e-66FFCP PHASE2:Hg19::chr8:28747682..28747705,-#_e22c587125abd623130560e8476a51e0p2@INTS9
1.3e-66FFCP PHASE2:Mm9::chr5:123440767..123440778,+#_51446c338142d253b86571136ce0e5d8p@chr5:123440767..123440778, +
1.3e-66FFCP PHASE2:Mm9::chr7:132751140..132751183,+#_51446c338142d253b86571136ce0e5d8p@chr7:132751140..132751183, +
1.3e-66FFCP PHASE1:Mm9::chr4:32422919..32422935,+#_51446c338142d253b86571136ce0e5d8p@chr4:32422919..32422935, +
1.3e-66FFCP PHASE1:Mm9::chr7:132751140..132751183,+#_51446c338142d253b86571136ce0e5d8p@chr7:132751140..132751183, +
1.3e-66FFCP PHASE1:Mm9::chr6:99215016..99215036,+#_51446c338142d253b86571136ce0e5d8p@chr6:99215016..99215036, +
1.3e-66FFCP PHASE2:Mm9::chr6:99215016..99215036,+#_51446c338142d253b86571136ce0e5d8p@chr6:99215016..99215036, +
1.3e-66FFCP PHASE1:Mm9::chr5:123440486..123440504,-#_51446c338142d253b86571136ce0e5d8p@chr5:123440486..123440504, -
1.3e-66FFCP PHASE2:Mm9::chr5:123440486..123440504,-#_51446c338142d253b86571136ce0e5d8p@chr5:123440486..123440504, -
1.3e-66FFCP PHASE2:Mm9::chr4:32422919..32422935,+#_51446c338142d253b86571136ce0e5d8p@chr4:32422919..32422935, +
1.3e-66FFCP PHASE1:Mm9::chr5:123440767..123440778,+#_51446c338142d253b86571136ce0e5d8p@chr5:123440767..123440778, +
2.39e-66FFCP PHASE2:Hg19::chr17:37934280..37934299,-#_366835de3f40311d2cff838607da28cbp6@IKZF3
2.39e-66FFCP PHASE1:Hg19::chr17:37934280..37934299,-#_366835de3f40311d2cff838607da28cbp6@IKZF3
2.74e-66FFCP PHASE2:Hg19::chr22:24823517..24823546,+#_027d7ee4672a6615d6da9071f066fd54p5@ADORA2A
2.74e-66FFCP PHASE1:Hg19::chr22:24823517..24823546,+#_027d7ee4672a6615d6da9071f066fd54p5@ADORA2A
2.91e-66FFCP PHASE2:Hg19::chr11:64107610..64107648,-#_5682e34c1f3ec8dedac1767b065ad0e4p@chr11:64107610..64107648, -
2.91e-66FFCP PHASE1:Hg19::chr11:64107610..64107648,-#_5682e34c1f3ec8dedac1767b065ad0e4p@chr11:64107610..64107648, -
3.71e-66FFCP PHASE2:Hg19::chr9:37037005..37037011,+#_4b71f98f8da93b06edf5877a0ca24b22p@chr9:37037005..37037011, +
3.71e-66FFCP PHASE1:Hg19::chr9:37037005..37037011,+#_4b71f98f8da93b06edf5877a0ca24b22p@chr9:37037005..37037011, +
1.64e-65FFCP PHASE1:Hg19::chr4:40198602..40198614,+#_6423826807d77cefa2bd2ebc6f604063p3@RHOH
1.64e-65FFCP PHASE2:Hg19::chr4:40198602..40198614,+#_6423826807d77cefa2bd2ebc6f604063p3@RHOH
2.06e-65FFCP PHASE1:Hg19::chr6:159528034..159528048,+#_7d2066fa5fb8fa3e1108ba030f551e99p@chr6:159528034..159528048, +
2.06e-65FFCP PHASE2:Hg19::chr6:159528034..159528048,+#_7d2066fa5fb8fa3e1108ba030f551e99p@chr6:159528034..159528048, +
3.38e-65FFCP PHASE1:Hg19::chr22:50318813..50318835,+#_5140abb2db8e89c118574e5cbcae72c6p@chr22:50318813..50318835, +
3.38e-65FFCP PHASE2:Hg19::chr22:50318813..50318835,+#_5140abb2db8e89c118574e5cbcae72c6p@chr22:50318813..50318835, +
5.98e-65FFCP PHASE2:Hg19::chr17:43487780..43487792,-#_ffdde82e7eeb0c8b2ffba2fd2e6e582ep5@ARHGAP27
5.98e-65FFCP PHASE1:Hg19::chr17:43487780..43487792,-#_ffdde82e7eeb0c8b2ffba2fd2e6e582ep5@ARHGAP27
6.07e-65FFCP PHASE2:Hg19::chr12:111106975..111106991,-#_8a72cd43772b448f52044779ffe9df17p@chr12:111106975..111106991, -
6.07e-65FFCP PHASE1:Hg19::chr12:111106975..111106991,-#_8a72cd43772b448f52044779ffe9df17p@chr12:111106975..111106991, -
6.91e-65FFCP PHASE1:Hg19::chr12:9822334..9822351,+#_f3221fe7e2dd4cca0ff54be37a01fe65p2@CLEC2D
6.91e-65FFCP PHASE2:Hg19::chr12:9822334..9822351,+#_f3221fe7e2dd4cca0ff54be37a01fe65p2@CLEC2D
1.1e-64FFCP PHASE1:Hg19::chr17:37917880..37917904,-#_1f5beaa7f8024df1b93efaeb00f99611p1@AK128436
1.1e-64FFCP PHASE2:Hg19::chr17:37917880..37917904,-#_1f5beaa7f8024df1b93efaeb00f99611p1@AK128436
1.11e-64FFCP PHASE2:Hg19::chr17:66176843..66176848,+#_05222c1503d5fc04c990ca1e928ef751p@chr17:66176843..66176848, +
1.11e-64FFCP PHASE1:Hg19::chr17:66176843..66176848,+#_05222c1503d5fc04c990ca1e928ef751p@chr17:66176843..66176848, +
1.25e-64FFCP PHASE2:Hg19::chr9:98257510..98257517,-#_184d929e35b523ddb1bcc9a722d4fbfbp@chr9:98257510..98257517, -
1.25e-64FFCP PHASE1:Hg19::chr9:98257510..98257517,-#_184d929e35b523ddb1bcc9a722d4fbfbp@chr9:98257510..98257517, -
1.33e-64FFCP PHASE1:Hg19::chr1:207085241..207085281,-#_9993875c82a7170903151bcbce0ba36ep@chr1:207085241..207085281, -
1.33e-64FFCP PHASE2:Hg19::chr1:207085241..207085281,-#_9993875c82a7170903151bcbce0ba36ep@chr1:207085241..207085281, -
1.78e-64FFCP PHASE2:Hg19::chr9:35650900..35650967,-#_88d9a3497aa56c26583ea0b3ed5660f6p1@SIT1
1.78e-64FFCP PHASE1:Hg19::chr9:35650900..35650967,-#_88d9a3497aa56c26583ea0b3ed5660f6p1@SIT1

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