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{{UBERON
{{UBERON
|id=UBERON:0001103
|alt_id=UBERON:FMA_13295-MA_0001904
|name=diaphragm
|anatomical_img_id=FMA:13295
|namespace=
|def="The diaphragm is a skeletal muscle that is responsible for contraction and expansion of the lungs[GO]." [GO:0060539, Wikipedia:Thoracid_diaphragm]
|xref=BTO:0000341;;EFO:0000937;;EHDAA2:0003495;;EMAPA:17701;;EV:0100376;;FMA:13295;;GAID:158;;MA:0001904;;MAT:0000502;;MESH:A.02.633.567.900.300;;ncithesaurus:Diaphragm;;OpenCyc:Mx4rvVivz5wpEbGdrcN5Y29ycA;;SCTID:181614006;;VHOG:0000713
|is_a=UBERON:0001134;;UBERON:0002426;;UBERON:0003831;;UBERON:0003898;;UBERON:0004830
|synonym="diaphragm muscle" EXACT [BTO:0000341];;"midriff" RELATED [BTO:0000341];;"phren" RELATED [BTO:0000341];;"thoracic diaphragm" EXACT []
|comment=The existence of some membrane separating the pharynx from the stomach can be traced widely among the chordates. Thus amphioxus possesses an atrium by which water exits the pharynx, which has been argued (and disputed) to be homologous to structures in ascidians and hagfishes.[3] The urochordate epicardium separates digestive organs from the pharynx and heart, but the anus returns to the upper compartment to discharge wastes through an outgoing siphon (Thoracic_diaphragm#Comparative_anatomy_and_evolution)
|comment=The existence of some membrane separating the pharynx from the stomach can be traced widely among the chordates. Thus amphioxus possesses an atrium by which water exits the pharynx, which has been argued (and disputed) to be homologous to structures in ascidians and hagfishes.[3] The urochordate epicardium separates digestive organs from the pharynx and heart, but the anus returns to the upper compartment to discharge wastes through an outgoing siphon (Thoracic_diaphragm#Comparative_anatomy_and_evolution)
|alt_id=UBERON:FMA_13295-MA_0001904
|disjoint_from=
|union_of=
|created_by=
|created_by=
|obo_creation_date=
|def="The diaphragm is a skeletal muscle that is responsible for contraction and expansion of the lungs[GO]." [GO:0060539, Wikipedia:Thoracid_diaphragm]
|subset=organ_slim;;uberon_slim
|adjacent_to=
|derives_from=
|derives_from=
|develops_from=UBERON:0010084
|develops_from=UBERON:0010084
|disjoint_from=
|has_quality=
|has_quality=
|id=UBERON:0001103
|is_a=UBERON:0003831 ;;UBERON:0004120 ;;UBERON:0005181
|is_obsolete=
|located_in=
|located_in=
|part_of=UBERON:0001004
|name=diaphragm
|property_value=IAO:0000412 http://purl.obolibrary.org/obo/uberon.owl
|namespace=FANTOM
|obo_creation_date=
|part_of=UBERON:0000915;;UBERON:0001004
|preceded_by=
|property_value=IAO:0000412 http://purl.obolibrary.org/obo/uberon.owl;;RO:0002161 NCBITaxon:8782
|subset=organ_slim;;uberon_slim
|synonym="diaphragm muscle" EXACT [BTO:0000341];;"midriff" RELATED [BTO:0000341];;"phren" RELATED [BTO:0000341];;"thoracic diaphragm" EXACT []
|union_of=
|xref=BTO:0000341;;EFO:0000937;;EHDAA2:0003495;;EMAPA:17701;;EV:0100376;;FMA:13295;;GAID:158;;MA:0001904;;MAT:0000502;;MESH:A.02.633.567.900.300;;ncithesaurus:Diaphragm;;OpenCyc:Mx4rvVivz5wpEbGdrcN5Y29ycA;;SCTID:181614006;;VHOG:0000713
}}
}}

Latest revision as of 17:15, 12 September 2014

Name:diaphragm
Namespace:FANTOM
Definition:"The diaphragm is a skeletal muscle that is responsible for contraction and expansion of the lungs[GO]." [GO:0060539, Wikipedia:Thoracid_diaphragm]
Xrefs:
links:

BTO:0000341
EFO:0000937
EHDAA2:0003495
EMAPA:17701
EV:0100376
FMA:13295
GAID:158
MA:0001904
MAT:0000502
MESH:A.02.633.567.900.300
ncithesaurus:Diaphragm
OpenCyc:Mx4rvVivz5wpEbGdrcN5Y29ycA
SCTID:181614006

VHOG:0000713
Synonyms: "diaphragm muscle" EXACT [BTO:0000341]
"midriff" RELATED [BTO:0000341]
"phren" RELATED [BTO:0000341]
"thoracic diaphragm" EXACT []
Comments:The existence of some membrane separating the pharynx from the stomach can be traced widely among the chordates. Thus amphioxus possesses an atrium by which water exits the pharynx, which has been argued (and disputed) to be homologous to structures in ascidians and hagfishes.[3] The urochordate epicardium separates digestive organs from the pharynx and heart, but the anus returns to the upper compartment to discharge wastes through an outgoing siphon (Thoracic_diaphragm#Comparative_anatomy_and_evolution)
Alt_id: UBERON:FMA_13295-MA_0001904
Subset: organ_slim
uberon_slim

Ontology association<br>Each term has an is_a parent in the Uberon Ontology, which has a linkage to an another entity and FANTOM5 samples.Libraries were grouped into mutually exclusive facets according to the FANTOM5 sample ontology mapping to UBERON ontologies.<br><br>link to ontology dataset<br>data

Parents

is_a:UBERON:0003831(respiratory system muscle),UBERON:0004120(mesoderm-derived structure),UBERON:0005181(thoracic segment organ)
develops_from:UBERON:0010084(future diaphragm)
part_of:UBERON:0000915(thoracic segment of trunk),UBERON:0001004(respiratory system)



Children

derives from:FF:0010069 (human diaphragm - fetal sample)
part of:FF:0010069 (human diaphragm - fetal sample)

Ontology Tree: Loaded from BioPortal

Ontorolgy tree(Small window open)

FF samples<br>It includes FANTOM5 samples that overlay the Uberon ontology

Human (Homo sapiens)


Enrichment analysis: top 100 FFCP enriched with this ontology term TOP 100 FANTOM5 Cage Peaks enriched with UBERON:0001103 (diaphragm), sorted by p-values <br>Analyst: Hideya Kawaji<br><br>link to source dataset <br>human : data <br>mouse : data

P-valueFFCPShort description
5.42e-195FFCP PHASE1:Hg19::chr18:10458574..10458579,-#_d8ffc08e39395d28d89353f6f1c7e0f7p@chr18:10458574..10458579, -
5.42e-195FFCP PHASE2:Hg19::chr18:10458574..10458579,-#_d8ffc08e39395d28d89353f6f1c7e0f7p@chr18:10458574..10458579, -
2.55e-98FFCP PHASE2:Hg19::chr9:101832711..101832718,+#_a67630c7dab3c7081c1e156d5c8c1c3dp@chr9:101832711..101832718, +
2.55e-98FFCP PHASE2:Hg19::chr17:39388700..39388702,+#_a67630c7dab3c7081c1e156d5c8c1c3dp1@KRTAP9-3, p1@KRTAP9-9
2.55e-98FFCP PHASE1:Hg19::chr9:101832711..101832718,+#_a67630c7dab3c7081c1e156d5c8c1c3dp@chr9:101832711..101832718, +
2.55e-98FFCP PHASE1:Hg19::chr20:31571662..31571664,+#_a67630c7dab3c7081c1e156d5c8c1c3dp@chr20:31571662..31571664, +
2.55e-98FFCP PHASE1:Hg19::chr1:223065664..223065673,+#_a67630c7dab3c7081c1e156d5c8c1c3dp@chr1:223065664..223065673, +
2.55e-98FFCP PHASE1:Hg19::chr17:39324471..39324474,-#_a67630c7dab3c7081c1e156d5c8c1c3dp1@KRTAP4-3
2.55e-98FFCP PHASE1:Hg19::chr3:112929906..112929910,+#_a67630c7dab3c7081c1e156d5c8c1c3dp13@BOC
2.55e-98FFCP PHASE2:Hg19::chr17:39394250..39394253,+#_a67630c7dab3c7081c1e156d5c8c1c3dp1@KRTAP9-8
2.55e-98FFCP PHASE1:Hg19::chr11:64518023..64518030,-#_a67630c7dab3c7081c1e156d5c8c1c3dp19@PYGM
2.55e-98FFCP PHASE1:Hg19::chr17:39334471..39334474,-#_a67630c7dab3c7081c1e156d5c8c1c3dp1@KRTAP4-2
2.55e-98FFCP PHASE2:Hg19::chr17:10428881..10428898,+#_a67630c7dab3c7081c1e156d5c8c1c3dp@chr17:10428881..10428898, +
2.55e-98FFCP PHASE2:Hg19::chr1:223065647..223065654,+#_a67630c7dab3c7081c1e156d5c8c1c3dp@chr1:223065647..223065654, +
2.55e-98FFCP PHASE2:Hg19::chr17:39306068..39306077,-#_a67630c7dab3c7081c1e156d5c8c1c3dp1@KRTAP4-5
2.55e-98FFCP PHASE2:Hg19::chr11:64518023..64518030,-#_a67630c7dab3c7081c1e156d5c8c1c3dp19@PYGM
2.55e-98FFCP PHASE1:Hg19::chr17:39388700..39388702,+#_a67630c7dab3c7081c1e156d5c8c1c3dp1@KRTAP9-3, p1@KRTAP9-9
2.55e-98FFCP PHASE2:Hg19::chr1:223065664..223065673,+#_a67630c7dab3c7081c1e156d5c8c1c3dp@chr1:223065664..223065673, +
2.55e-98FFCP PHASE2:Hg19::chr20:31571662..31571664,+#_a67630c7dab3c7081c1e156d5c8c1c3dp@chr20:31571662..31571664, +
2.55e-98FFCP PHASE1:Hg19::chr8:115584851..115584862,+#_a67630c7dab3c7081c1e156d5c8c1c3dp@chr8:115584851..115584862, +
2.55e-98FFCP PHASE2:Hg19::chr17:39324471..39324474,-#_a67630c7dab3c7081c1e156d5c8c1c3dp1@KRTAP4-3
2.55e-98FFCP PHASE2:Hg19::chr3:112929906..112929910,+#_a67630c7dab3c7081c1e156d5c8c1c3dp13@BOC
2.55e-98FFCP PHASE2:Hg19::chr8:115584851..115584862,+#_a67630c7dab3c7081c1e156d5c8c1c3dp@chr8:115584851..115584862, +
2.55e-98FFCP PHASE1:Hg19::chr17:39394250..39394253,+#_a67630c7dab3c7081c1e156d5c8c1c3dp1@KRTAP9-8
2.55e-98FFCP PHASE1:Hg19::chr17:10428881..10428898,+#_a67630c7dab3c7081c1e156d5c8c1c3dp@chr17:10428881..10428898, +
2.55e-98FFCP PHASE2:Hg19::chr17:39334471..39334474,-#_a67630c7dab3c7081c1e156d5c8c1c3dp1@KRTAP4-2
2.55e-98FFCP PHASE1:Hg19::chr1:223065647..223065654,+#_a67630c7dab3c7081c1e156d5c8c1c3dp@chr1:223065647..223065654, +
2.55e-98FFCP PHASE1:Hg19::chr17:39306068..39306077,-#_a67630c7dab3c7081c1e156d5c8c1c3dp1@KRTAP4-5
1.23e-66FFCP PHASE1:Hg19::chr10:75226166..75226169,-#_925471bc7373bb933351ef5d38cfe180p6@PPP3CB
1.23e-66FFCP PHASE2:Hg19::chr19:50994855..50994864,-#_925471bc7373bb933351ef5d38cfe180p@chr19:50994855..50994864, -
1.23e-66FFCP PHASE2:Hg19::chr10:75226166..75226169,-#_925471bc7373bb933351ef5d38cfe180p6@PPP3CB
1.23e-66FFCP PHASE2:Hg19::chr12:102075405..102075407,+#_925471bc7373bb933351ef5d38cfe180p@chr12:102075405..102075407, +
1.23e-66FFCP PHASE1:Hg19::chr12:102075405..102075407,+#_925471bc7373bb933351ef5d38cfe180p@chr12:102075405..102075407, +
1.23e-66FFCP PHASE1:Hg19::chr19:50994855..50994864,-#_925471bc7373bb933351ef5d38cfe180p@chr19:50994855..50994864, -
1.23e-66FFCP PHASE2:Hg19::chr11:126077478..126077485,-#_925471bc7373bb933351ef5d38cfe180p4@RPUSD4
1.23e-66FFCP PHASE1:Hg19::chr11:126077478..126077485,-#_925471bc7373bb933351ef5d38cfe180p4@RPUSD4
2.39e-66FFCP PHASE1:Hg19::chr2:179588230..179588237,-#_b35d78b88276d23fc72523af44aa9341p@chr2:179588230..179588237, -
2.39e-66FFCP PHASE2:Hg19::chr10:24407264..24407270,-#_b35d78b88276d23fc72523af44aa9341p@chr10:24407264..24407270, -
2.39e-66FFCP PHASE2:Hg19::chr11:1955193..1955200,+#_b35d78b88276d23fc72523af44aa9341p23@TNNT3
2.39e-66FFCP PHASE1:Hg19::chr2:179548750..179548755,-#_b35d78b88276d23fc72523af44aa9341p@chr2:179548750..179548755, -
2.39e-66FFCP PHASE2:Hg19::chr2:26700872..26700884,-#_b35d78b88276d23fc72523af44aa9341p5@OTOF
2.39e-66FFCP PHASE2:Hg19::chr17:10533450..10533457,+#_b35d78b88276d23fc72523af44aa9341p@chr17:10533450..10533457, +
2.39e-66FFCP PHASE1:Hg19::chr2:179542420..179542428,-#_b35d78b88276d23fc72523af44aa9341p@chr2:179542420..179542428, -
2.39e-66FFCP PHASE2:Hg19::chr15:99548796..99548805,-#_b35d78b88276d23fc72523af44aa9341p3@PGPEP1L
2.39e-66FFCP PHASE1:Hg19::chr5:7727283..7727284,+#_b35d78b88276d23fc72523af44aa9341p19@ADCY2
2.39e-66FFCP PHASE2:Hg19::chr12:68185216..68185218,+#_b35d78b88276d23fc72523af44aa9341p@chr12:68185216..68185218, +
2.39e-66FFCP PHASE2:Hg19::chr2:179588230..179588237,-#_b35d78b88276d23fc72523af44aa9341p@chr2:179588230..179588237, -
2.39e-66FFCP PHASE1:Hg19::chr15:99548796..99548805,-#_b35d78b88276d23fc72523af44aa9341p3@PGPEP1L
2.39e-66FFCP PHASE1:Hg19::chr4:26165179..26165190,+#_b35d78b88276d23fc72523af44aa9341p47@RBPJ
2.39e-66FFCP PHASE1:Hg19::chr19:50997736..50997745,-#_b35d78b88276d23fc72523af44aa9341p@chr19:50997736..50997745, -
2.39e-66FFCP PHASE1:Hg19::chr12:68185216..68185218,+#_b35d78b88276d23fc72523af44aa9341p@chr12:68185216..68185218, +
2.39e-66FFCP PHASE2:Hg19::chr7:123241760..123241766,-#_b35d78b88276d23fc72523af44aa9341p@chr7:123241760..123241766, -
2.39e-66FFCP PHASE1:Hg19::chr7:123241760..123241766,-#_b35d78b88276d23fc72523af44aa9341p@chr7:123241760..123241766, -
2.39e-66FFCP PHASE2:Hg19::chr2:179548750..179548755,-#_b35d78b88276d23fc72523af44aa9341p@chr2:179548750..179548755, -
2.39e-66FFCP PHASE1:Hg19::chr2:26700872..26700884,-#_b35d78b88276d23fc72523af44aa9341p5@OTOF
2.39e-66FFCP PHASE2:Hg19::chr14:97684658..97684662,+#_b35d78b88276d23fc72523af44aa9341p@chr14:97684658..97684662, +
2.39e-66FFCP PHASE1:Hg19::chr17:10533450..10533457,+#_b35d78b88276d23fc72523af44aa9341p@chr17:10533450..10533457, +
2.39e-66FFCP PHASE2:Hg19::chr4:26165179..26165190,+#_b35d78b88276d23fc72523af44aa9341p47@RBPJ
2.39e-66FFCP PHASE2:Hg19::chr2:179542420..179542428,-#_b35d78b88276d23fc72523af44aa9341p@chr2:179542420..179542428, -
2.39e-66FFCP PHASE2:Hg19::chr5:7727283..7727284,+#_b35d78b88276d23fc72523af44aa9341p19@ADCY2
2.39e-66FFCP PHASE1:Hg19::chr10:99343436..99343448,+#_b35d78b88276d23fc72523af44aa9341p@chr10:99343436..99343448, +
2.39e-66FFCP PHASE1:Hg19::chr14:97684658..97684662,+#_b35d78b88276d23fc72523af44aa9341p@chr14:97684658..97684662, +
2.39e-66FFCP PHASE1:Hg19::chr10:24407264..24407270,-#_b35d78b88276d23fc72523af44aa9341p@chr10:24407264..24407270, -
2.39e-66FFCP PHASE2:Hg19::chr10:99343436..99343448,+#_b35d78b88276d23fc72523af44aa9341p@chr10:99343436..99343448, +
2.39e-66FFCP PHASE2:Hg19::chr19:50997736..50997745,-#_b35d78b88276d23fc72523af44aa9341p@chr19:50997736..50997745, -
2.39e-66FFCP PHASE1:Hg19::chr11:1955193..1955200,+#_b35d78b88276d23fc72523af44aa9341p23@TNNT3
4.66e-66FFCP PHASE2:Hg19::chr2:152419209..152419216,-#_da4f32d7ac5a48e875c701177db561a4p@chr2:152419209..152419216, -
4.66e-66FFCP PHASE1:Hg19::chr2:152393686..152393693,-#_da4f32d7ac5a48e875c701177db561a4p@chr2:152393686..152393693, -
4.66e-66FFCP PHASE1:Hg19::chr2:152476098..152476105,-#_da4f32d7ac5a48e875c701177db561a4p@chr2:152476098..152476105, -
4.66e-66FFCP PHASE1:Hg19::chr17:39507076..39507080,-#_da4f32d7ac5a48e875c701177db561a4p1@KRT33A
4.66e-66FFCP PHASE2:Hg19::chr2:168106984..168106993,+#_da4f32d7ac5a48e875c701177db561a4p34@XIRP2
4.66e-66FFCP PHASE2:Hg19::chr2:168105377..168105386,+#_da4f32d7ac5a48e875c701177db561a4p28@XIRP2
4.66e-66FFCP PHASE2:Hg19::chr2:152342364..152342373,-#_da4f32d7ac5a48e875c701177db561a4p@chr2:152342364..152342373, -
4.66e-66FFCP PHASE1:Hg19::chr2:152514527..152514536,-#_da4f32d7ac5a48e875c701177db561a4p@chr2:152514527..152514536, -
4.66e-66FFCP PHASE2:Hg19::chr12:52695617..52695623,+#_da4f32d7ac5a48e875c701177db561a4p4@KRT86
4.66e-66FFCP PHASE1:Hg19::chr12:52695617..52695623,+#_da4f32d7ac5a48e875c701177db561a4p4@KRT86
4.66e-66FFCP PHASE1:Hg19::chr17:38911580..38911584,-#_da4f32d7ac5a48e875c701177db561a4p1@KRT25
4.66e-66FFCP PHASE2:Hg19::chr13:28961100..28961122,-#_da4f32d7ac5a48e875c701177db561a4p14@FLT1
4.66e-66FFCP PHASE1:Hg19::chr13:28961100..28961122,-#_da4f32d7ac5a48e875c701177db561a4p14@FLT1
4.66e-66FFCP PHASE2:Hg19::chr17:10544511..10544520,-#_da4f32d7ac5a48e875c701177db561a4p@chr17:10544511..10544520, -
4.66e-66FFCP PHASE1:Hg19::chr17:38938796..38938803,-#_da4f32d7ac5a48e875c701177db561a4p1@KRT27
4.66e-66FFCP PHASE2:Hg19::chr8:82373809..82373815,-#_da4f32d7ac5a48e875c701177db561a4p1@FABP9
4.66e-66FFCP PHASE1:Hg19::chr8:82373809..82373815,-#_da4f32d7ac5a48e875c701177db561a4p1@FABP9
4.66e-66FFCP PHASE1:Hg19::chr2:152419209..152419216,-#_da4f32d7ac5a48e875c701177db561a4p@chr2:152419209..152419216, -
4.66e-66FFCP PHASE2:Hg19::chr2:152393686..152393693,-#_da4f32d7ac5a48e875c701177db561a4p@chr2:152393686..152393693, -
4.66e-66FFCP PHASE2:Hg19::chr2:152476098..152476105,-#_da4f32d7ac5a48e875c701177db561a4p@chr2:152476098..152476105, -
4.66e-66FFCP PHASE2:Hg19::chr17:39507076..39507080,-#_da4f32d7ac5a48e875c701177db561a4p1@KRT33A
4.66e-66FFCP PHASE1:Hg19::chr2:168106984..168106993,+#_da4f32d7ac5a48e875c701177db561a4p34@XIRP2
4.66e-66FFCP PHASE1:Hg19::chr2:168105377..168105386,+#_da4f32d7ac5a48e875c701177db561a4p28@XIRP2
4.66e-66FFCP PHASE2:Hg19::chr2:152514527..152514536,-#_da4f32d7ac5a48e875c701177db561a4p@chr2:152514527..152514536, -
4.66e-66FFCP PHASE1:Hg19::chr2:152342364..152342373,-#_da4f32d7ac5a48e875c701177db561a4p@chr2:152342364..152342373, -
4.66e-66FFCP PHASE2:Hg19::chr17:38911580..38911584,-#_da4f32d7ac5a48e875c701177db561a4p1@KRT25
4.66e-66FFCP PHASE1:Hg19::chr17:10544511..10544520,-#_da4f32d7ac5a48e875c701177db561a4p@chr17:10544511..10544520, -
4.66e-66FFCP PHASE2:Hg19::chr17:38938796..38938803,-#_da4f32d7ac5a48e875c701177db561a4p1@KRT27
1.46e-50FFCP PHASE2:Hg19::chr1:236861252..236861256,+#_93c3b131f2fe605bb88959af7590dcbfp@chr1:236861252..236861256, +
1.46e-50FFCP PHASE2:Hg19::chr10:35104131..35104138,-#_93c3b131f2fe605bb88959af7590dcbfp4@PARD3
1.46e-50FFCP PHASE2:Hg19::chr2:152520289..152520294,-#_93c3b131f2fe605bb88959af7590dcbfp@chr2:152520289..152520294, -
1.46e-50FFCP PHASE1:Hg19::chr22:32647133..32647135,-#_93c3b131f2fe605bb88959af7590dcbfp@chr22:32647133..32647135, -
1.46e-50FFCP PHASE2:Hg19::chr11:94476841..94476846,+#_93c3b131f2fe605bb88959af7590dcbfp@chr11:94476841..94476846, +
1.46e-50FFCP PHASE1:Hg19::chrX:21672387..21672391,-#_93c3b131f2fe605bb88959af7590dcbfp@chrX:21672387..21672391, -

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