UBERON:0007100: Difference between revisions
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|is_obsolete= | |is_obsolete= | ||
|located_in= | |located_in= | ||
|name=circulatory organ | |name=primary circulatory organ | ||
|namespace= | |namespace=FANTOM | ||
|obo_creation_date= | |obo_creation_date= | ||
|part_of=UBERON:0001009 | |part_of=UBERON:0001009 |
Latest revision as of 18:00, 12 September 2014
Name: | primary circulatory organ | |
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Namespace: | FANTOM | |
Definition: | "A hollow, muscular organ, which, by contracting rhythmically, keeps up the circulation of the blood[GO]." [GO:0007507] | |
Xrefs: |
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Synonyms: |
"adult heart" RELATED [FBbt:00003154] "cardiac pump" EXACT [] "cardiac structure" RELATED [] "dorsal tube" NARROW [Wikipedia:Heart] "heart" NARROW [GO:0007507] "heart or heart like organ" EXACT [] | |
Comments: | editor note: we need to find the appropriate GO process to use for the definition - 'blood circulation' may not apply to invertebrates; 'circulatory system process' is circular. Note we cannot use a part_of-based definition as this results in the iris and all vascular elements being categorized as circulatory organs. Taxon notes: note we reserve the subclass 'heart' from the vertebrate multi-chambered heart. "The first heart-like organ is believed to have appeared 500my ago in an ancestral bilaterian". Amniotes: four-chambered heart. Amphibians: two atria, one ventricle, pulmonary; fish: single atrium and ventricle; amphioxus: tubular, non-striated, closed, unidirectional; ascidians: tubular, striated, open, bidirectional; arthropods: tubular, open; C elegans: contractile pharynx; Cnideria: striated muscle cells associated with gastrodermis. Gene notes: Bmp, Nkx, Gata | |
Subset: | grouping_class |
Ontology association<br>Each term has an is_a parent in the Uberon Ontology, which has a linkage to an another entity and FANTOM5 samples.Libraries were grouped into mutually exclusive facets according to the FANTOM5 sample ontology mapping to UBERON ontologies.<br><br>link to ontology dataset<br>data
Parents
is_a: | UBERON:0015228(circulatory organ) |
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part_of: | UBERON:0001009(circulatory system) |
Children
is a: | UBERON:0000948 (heart) |
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part of: | CL:0000746 (cardiac muscle cell),CL:0002494 (cardiocyte) |
Ontology Tree: Loaded from BioPortal
Ontorolgy tree(Small window open)
FF samples<br>It includes FANTOM5 samples that overlay the Uberon ontology
Human (Homo sapiens)
- 10016-101C7 (heart, adult, pool1)
- 10046-101G1 (heart, fetal, pool1)
- 10050-101G5 (heart, adult, diseased post-infarction, donor1)
- 10051-101G6 (heart, adult, diseased, donor1)
- 10078-102A6 (left ventricle, adult, donor1)
- 10079-102A7 (left atrium, adult, donor1)
- 10087-102B6
- 10205-103F7 (heart - mitral valve, adult)
- 10206-103F8 (heart - pulmonic valve, adult)
- 10207-103F9 (heart - tricuspid valve, adult)
... further results Mouse (Mus musculus)
- 10016-101C7 (heart, adult, pool1)
- 10046-101G1 (heart, fetal, pool1)
- 10050-101G5 (heart, adult, diseased post-infarction, donor1)
- 10051-101G6 (heart, adult, diseased, donor1)
- 10078-102A6 (left ventricle, adult, donor1)
- 10079-102A7 (left atrium, adult, donor1)
- 10087-102B6
- 10205-103F7 (heart - mitral valve, adult)
- 10206-103F8 (heart - pulmonic valve, adult)
- 10207-103F9 (heart - tricuspid valve, adult)
Enrichment analysis: top 100 FFCP enriched with this ontology term TOP 100 FANTOM5 Cage Peaks enriched with UBERON:0007100 (primary circulatory organ), sorted by p-values <br>Analyst: Hideya Kawaji<br><br>link to source dataset <br>human : data <br>mouse : data