FF:10788-110H5: Difference between revisions
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{{f5samples | {{f5samples | ||
| | |DRA_sample_Accession=CAGE@SAMD00004756 | ||
| | |accession_numbers=CAGE;DRX007803;DRR008675;DRZ000100;DRZ001485;DRZ011450;DRZ012835 | ||
| | |ancestors_in_anatomy_facet= | ||
| | |ancestors_in_cell_lineage_facet=CL:0000000,CL:0000003,CL:0000988,CL:0000548,CL:0000763,CL:0002371,CL:0000255 | ||
| | |ancestors_in_disease_facet=DOID:4,DOID:0050686,DOID:162,DOID:2531,DOID:14566,DOID:0060083,DOID:1240,DOID:8692 | ||
|ancestors_in_ff_facet=FF:0000102,FF:0000003,FF:0000210,FF:0000101,FF:0000001,FF:0100737,FF:0101035,FF:0101883,FF:0100740 | |||
| | |comment= | ||
| | |created_by= | ||
|creation_date= | |||
|data_phase=2 | |||
| | |datafreeze_phase=2 | ||
| | |def= | ||
| | |expression_enrichment_score=chr2:68592406..68592424,+!p1@PLEK!2.36!229.51!PLEK;;chr6:135502501..135502546,+!p1@MYB!2.03!124.98!MYB;;chr1:92949331..92949377,-!p2@GFI1!1.98!95.44!GFI1;;chr11:47400078..47400106,-!p1@SPI1!1.90!78.88!SPI1;;chr19:13213662..13213686,-!p1@LYL1!1.78!87.00!LYL1;;chr6:135502408..135502459,+!p2@MYB!1.77!67.52!MYB;;chr7:50344289..50344323,+!p1@IKZF1!1.74!53.56!IKZF1;;chr21:39870339..39870443,-!p1@ERG!1.71!50.32!ERG;;chr1:92951607..92951661,-!p1@GFI1!1.63!41.23!GFI1;;chr7:137620650..137620677,-!p3@CREB3L2!1.49!30.19!CREB3L2;;chr22:19748231..19748317,+!p1@TBX1!1.44!26.62!TBX1;;chr7:115670804..115670825,-!p1@TFEC!1.43!25.97!TFEC;;chr5:88178983..88179012,-!p1@MEF2C!1.25!126.28!MEF2C;;chr6:144385698..144385742,-!p2@PLAGL1!1.25!20.45!PLAGL1;;chr11:47399996..47400014,-!p4@SPI1!1.25!16.88!SPI1;;chr7:137620684..137620711,-!p4@CREB3L2!1.24!16.56!CREB3L2;;chr6:135502472..135502489,+!p3@MYB!1.23!15.91!MYB;;chr2:68592394..68592405,+!p2@PLEK!1.22!15.58!PLEK;;chr16:54320646..54320672,-!p2@IRX3!1.20!22.72!IRX3;;chr2:145277640..145277771,-!p1@ZEB2!1.17!181.14!ZEB2;;chr19:13213954..13214021,-!p4@LYL1!1.17!13.96!LYL1;;chr21:36421535..36421610,-!p2@RUNX1!1.16!47.72!RUNX1;;chr2:185463247..185463263,+!p1@ZNF804A!1.15!23.37!ZNF804A;;chr3:18486354..18486377,-!p2@SATB1!1.15!16.56!SATB1;;chr3:71631151..71631194,-!p15@FOXP1!1.15!14.93!FOXP1;;chr10:70320074..70320106,+!p1@TET1!1.13!25.32!TET1;;chr10:94449703..94449718,+!p1@HHEX!1.12!47.07!HHEX;;chr11:47399947..47399961,-!p3@SPI1!1.11!12.01!SPI1;;chr11:128563948..128564003,+!p1@FLI1!1.09!136.34!FLI1;;chr2:60780607..60780624,-!p2@BCL11A!1.08!33.76!BCL11A;;chr16:54320617..54320643,-!p3@IRX3!1.08!14.28!IRX3;;chr11:47400062..47400077,-!p2@SPI1!1.08!11.04!SPI1;;chr1:92949505..92949543,-!p5@GFI1!1.08!11.04!GFI1;;chr8:128748308..128748324,+!p2@MYC!1.07!299.95!MYC;;chr3:71630980..71631110,-!p3@FOXP1!1.06!36.68!FOXP1;;chr7:64126535..64126559,+!p2@ZNF107!1.05!22.07!ZNF107;;chr2:74726710..74726736,-!p3@LBX2!1.04!10.06!LBX2;;chr7:50343634..50343717,+!p2@IKZF1!1.02!9.41!IKZF1;;chr4:81118647..81118666,+!p1@PRDM8!1.00!12.01!PRDM8;;chr16:54320675..54320715,-!p1@IRX3!0.97!18.50!IRX3;;chr10:94449675..94449694,+!p2@HHEX!0.96!22.40!HHEX;;chr7:113726357..113726443,+!p1@FOXP2!0.93!13.31!FOXP2;;chr16:54319010..54319041,-!p8@IRX3!0.93!7.47!IRX3;;chr17:42295777..42295816,-!p7@UBTF!0.91!8.76!UBTF;;chr2:60780753..60780800,-!p1@BCL11A!0.90!35.71!BCL11A;;chr5:88120151..88120177,-!p6@MEF2C!0.89!6.82!MEF2C;;chr11:47400045..47400060,-!p6@SPI1!0.89!6.82!SPI1;;chr12:54778471..54778528,-!p1@ZNF385A!0.89!6.82!ZNF385A;;chr21:36260980..36261011,-!p1@RUNX1!0.88!198.67!RUNX1;;chr8:145669791..145669834,-!p1@TONSL!0.87!19.15!TONSL;;chr12:11802547..11802560,+!p5@ETV6!0.87!9.09!ETV6;;chrX:84499081..84499115,+!p2@ZNF711!0.86!9.41!ZNF711;;chr14:75988771..75988826,+!p1@BATF!0.86!8.44!BATF;;chr17:42295682..42295731,-!p17@UBTF!0.84!5.84!UBTF;;chr7:50344251..50344288,+!p3@IKZF1!0.84!5.84!IKZF1;;chr11:47400032..47400043,-!p5@SPI1!0.84!5.84!SPI1;;chr1:167298300..167298319,+!p2@POU2F1!0.84!5.84!POU2F1;;chrX:66763856..66763896,+!p1@AR!0.83!8.44!AR;;chrX:131624056..131624069,-!p2@MBNL3!0.83!8.12!MBNL3;;chr17:40440481..40440550,+!p1@STAT5A!0.82!42.85!STAT5A;;chr7:128577972..128578047,+!p1@IRF5!0.82!9.09!IRF5;;chr16:54964740..54964789,+!p1@IRX5!0.82!8.44!IRX5;;chr19:13213704..13213726,-!p3@LYL1!0.81!7.47!LYL1;;chr2:25475120..25475176,-!p2@DNMT3A!0.81!7.47!DNMT3A;;chr10:31288398..31288455,-!p2@ZNF438!0.81!6.49!ZNF438;;chr16:54320280..54320291,-!p9@IRX3!0.81!5.52!IRX3;;chr16:54320302..54320317,-!p10@IRX3!0.81!5.52!IRX3;;chr1:92952473..92952489,-!p3@GFI1!0.81!5.52!GFI1;;chr6:135516877..135516900,+!p5@MYB!0.81!5.52!MYB;;chr7:27183291..27183324,-!p1@HOXA5!0.81!5.52!HOXA5;;chr19:11959532..11959593,+!p1@ZNF439!0.80!21.75!ZNF439;;chr20:42295745..42295765,+!p1@MYBL2!0.79!91.22!MYBL2;;chrX:101186981..101187030,-!p1@ZMAT1!0.79!18.18!ZMAT1;;chr8:60031619..60031676,-!p1@TOX!0.79!11.69!TOX;;chr6:126240463..126240489,+!p6@NCOA7!0.79!5.84!NCOA7;;chr16:31885093..31885165,+!p1@ZNF267!0.78!84.73!ZNF267;;chr5:176738887..176738934,-!p1@MXD3!0.77!35.38!MXD3;;chr13:41593425..41593480,-!p1@ELF1!0.77!34.09!ELF1;;chr10:51572408..51572454,+!p3@NCOA4!0.77!31.49!NCOA4;;chr10:111967345..111967422,+!p1@MXI1!0.76!86.67!MXI1;;chrX:66763815..66763854,+!p2@AR!0.76!6.49!AR;;chr19:13213511..13213545,-!p2@LYL1!0.76!5.19!LYL1;;chr11:130184470..130184533,-!p2@ZBTB44!0.75!13.63!ZBTB44;;chr5:88179195..88179224,-!p3@MEF2C!0.75!7.79!MEF2C;;chr6:21597765..21597779,+!p2@SOX4!0.74!40.58!SOX4;;chr2:60778035..60778060,-!p4@BCL11A!0.74!5.52!BCL11A;;chr6:135513595..135513617,+!p4@MYB!0.74!4.54!MYB;;chr7:27183263..27183284,-!p2@HOXA5!0.74!4.54!HOXA5;;chr19:12203100..12203132,+!p1@ZNF788!0.73!9.41!ZNF788;;chr16:54320158..54320200,-!p5@IRX3!0.73!6.49!IRX3;;chr1:153940354..153940395,+!p1@CREB3L4!0.72!19.15!CREB3L4;;chr1:93544791..93544807,+!p2@MTF2!0.72!6.82!MTF2;;chr12:11802600..11802685,+!p1@ETV6!0.71!70.44!ETV6;;chr7:149470641..149470694,-!p1@ZNF467!0.70!20.45!ZNF467;;chr5:88179017..88179046,-!p2@MEF2C!0.70!17.85!MEF2C;;chr5:138609782..138609826,+!p5@MATR3!0.69!28.89!MATR3;;chr6:100061724..100061753,+!p1@PRDM13!0.69!3.90!PRDM13;;chr14:23588242..23588262,-!p1@CEBPE!0.69!3.90!CEBPE;;chr16:54320322..54320343,-!p7@IRX3!0.69!3.90!IRX3;;chr2:25475094..25475112,-!p3@DNMT3A!0.69!3.90!DNMT3A;;chr6:21593973..21593988,+!p1@SOX4!0.68!158.09!SOX4;;chr6:15246200..15246214,+!p2@JARID2!0.68!11.69!JARID2;;chr10:76585205..76585251,+!p3@KAT6B!0.68!9.09!KAT6B;;chr6:126240380..126240430,+!p2@NCOA7!0.67!10.71!NCOA7;;chr6:45390300..45390335,+!p4@RUNX2!0.67!6.17!RUNX2;;chr1:247171316..247171336,-!p3@ZNF695!0.67!5.84!ZNF695;;chrX:70503529..70503549,+!p2@NONO!0.66!22.07!NONO;;chrX:131623982..131624011,-!p6@MBNL3!0.66!5.52!MBNL3;;chr11:32457103..32457123,-!p3@WT1!0.66!3.57!WT1;;chr2:185463521..185463557,+!p3@ZNF804A!0.66!3.57!ZNF804A;;chr14:45722360..45722415,-!p1@MIS18BP1!0.65!62.98!MIS18BP1;;chr2:239148671..239148686,-!p1@HES6!0.64!14.28!HES6;;chr10:51572339..51572376,+!p4@NCOA4!0.64!8.44!NCOA4;;chr6:21597514..21597578,+!p4@SOX4!0.64!6.17!SOX4;;chr3:42947600..42947680,+!p1@ZNF662!0.64!5.19!ZNF662;;chr19:45579725..45579743,-!p1@ZNF296!0.63!17.20!ZNF296;;chr19:20011744..20011770,+!p1@ZNF93!0.63!14.61!ZNF93;;chr2:169312725..169312810,+!p1@CERS6!0.62!91.22!CERS6;;chr14:74353454..74353469,+!p4@ZNF410!0.62!6.82!ZNF410;;chr11:130184311..130184362,-!p4@ZBTB44!0.62!6.17!ZBTB44;;chr22:29196547..29196563,-!p2@XBP1!0.61!136.67!XBP1;;chr6:42419649..42419673,-!p3@TRERF1!0.61!5.84!TRERF1;;chr7:149470540..149470596,-!p2@ZNF467!0.61!4.22!ZNF467;;chr8:128748470..128748487,+!p1@MYC!0.60!399.93!MYC;;chr6:41040678..41040722,+!p1@NFYA!0.60!73.36!NFYA;;chr19:23433144..23433204,-!p1@ZNF724P!0.60!15.91!ZNF724P;;chr4:47916543..47916580,-!p2@NFXL1!0.60!11.69!NFXL1;;chr19:12035937..12035969,+!p3@ZNF700,p4@ZNF763!0.60!4.22!ZNF700;;chr19:48774586..48774670,+!p1@ZNF114!0.60!3.90!ZNF114;;chr19:47538560..47538591,+!p2@NPAS1!0.59!2.92!NPAS1;;chr1:92950138..92950159,-!p4@GFI1!0.59!2.92!GFI1;;chr6:135516909..135516925,+!p6@MYB!0.59!2.92!MYB;;chr20:42295713..42295738,+!p2@MYBL2!0.58!20.13!MYBL2;;chr10:44101850..44101896,+!p1@ZNF485!0.58!10.39!ZNF485;;chr6:45390269..45390298,+!p5@RUNX2!0.58!5.19!RUNX2;;chr10:38383255..38383324,+!p1@ZNF37A!0.57!31.49!ZNF37A;;chr1:202777535..202777556,-!p1@KDM5B!0.56!111.02!KDM5B;;chr11:695006..695074,-!p1@DEAF1!0.56!51.94!DEAF1;;chr19:20188776..20188826,+!p1@ZNF90!0.56!8.44!ZNF90;;chr10:48355030..48355090,+!p1@ZNF488!0.56!3.57!ZNF488;;chr1:158985469..158985489,+!p7@IFI16!0.56!3.25!IFI16;;chr21:38071403..38071428,+!p2@SIM2!0.56!2.60!SIM2;;chr11:47399920..47399931,-!p7@SPI1!0.56!2.60!SPI1;;chr2:145277589..145277612,-!p12@ZEB2!0.56!2.60!ZEB2;;chr15:90544182..90544195,+!p7@ZNF710!0.56!2.60!ZNF710;;chr19:13213634..13213645,-!p8@LYL1!0.56!2.60!LYL1;;chr19:13213691..13213696,-!p9@LYL1!0.56!2.60!LYL1;;chr8:123793708..123793723,+!p6@ZHX2!0.56!2.60!ZHX2;;chr6:7107999..7108031,+!p2@RREB1!0.55!16.88!RREB1;;chr6:20402102..20402152,+!p1@E2F3!0.55!12.66!E2F3;;chr3:44626446..44626477,+!p1@ZNF660!0.55!5.19!ZNF660;;chr16:54320101..54320125,-!p4@IRX3!0.55!3.90!IRX3;;chr4:331578..331615,+!p1@ZNF141!0.54!33.76!ZNF141;;chr7:64126503..64126528,+!p1@ZNF107!0.54!22.07!ZNF107;;chr14:74226961..74227020,-!p1@C14orf43!0.54!20.45!C14orf43;;chr6:144329500..144329526,-!p4@PLAGL1!0.54!6.82!PLAGL1;;chr14:89628064..89628109,-!p4@FOXN3!0.54!5.84!FOXN3;;chr6:45390002..45390023,+!p6@RUNX2!0.54!4.87!RUNX2;;chr6:45296048..45296082,+!p1@RUNX2!0.54!2.92!RUNX2;;chr17:61920023..61920110,-!p1@SMARCD2!0.53!43.50!SMARCD2;;chr22:20748434..20748455,+!p1@ZNF74!0.53!9.09!ZNF74;;chr19:37096139..37096170,-!p2@ZNF529!0.53!8.12!ZNF529;;chr22:50247528..50247568,+!p2@ZBED4!0.53!6.82!ZBED4;;chr1:25256756..25256774,-!p1@RUNX3!0.53!5.19!RUNX3;;chr19:20011775..20011800,+!p2@ZNF93!0.53!4.87!ZNF93;;chr15:77713299..77713316,+!p3@HMG20A!0.53!4.22!HMG20A;;chr10:21823243..21823290,+!p2@MLLT10!0.52!12.66!MLLT10;;chr4:81104895..81104920,+!p2@PRDM8!0.52!3.90!PRDM8;;chr6:34204642..34204664,+!p2@HMGA1!0.51!392.79!HMGA1;;chr16:68119324..68119364,+!p1@NFATC3!0.51!12.66!NFATC3;;chr19:33793430..33793447,-!p1@CEBPA!0.51!12.01!CEBPA;;chr6:45390025..45390076,+!p2@RUNX2!0.51!6.49!RUNX2;;chr18:47814010..47814021,-!p3@CXXC1!0.51!4.22!CXXC1;;chr20:35202909..35202963,+!p2@TGIF2,p3@C20orf24!0.51!3.57!TGIF2;;chr2:208031943..208031978,-!p5@KLF7!0.51!3.25!KLF7;;chr4:81104985..81105005,+!p4@PRDM8!0.51!2.92!PRDM8;;chr22:21771656..21771662,+!p1@HIC2!0.51!2.27!HIC2;;chr7:27224842..27224872,-!p1@HOXA11!0.51!2.27!HOXA11;;chr9:124976299..124976327,-!p3@LHX6!0.51!2.27!LHX6;;chr9:124976328..124976372,-!p2@LHX6!0.51!2.27!LHX6;;chr10:38299412..38299430,+!p2@ZNF33A!0.51!2.27!ZNF33A;;chr10:70320041..70320065,+!p2@TET1!0.51!2.27!TET1;;chr14:23588458..23588473,-!p2@CEBPE!0.51!2.27!CEBPE;;chr9:37027156..37027193,-!p4@PAX5!0.51!2.27!PAX5;;chr1:158978768..158978800,+!p8@IFI16!0.51!2.27!IFI16;;chr21:36421147..36421193,-!p10@RUNX1!0.51!2.27!RUNX1;;chr19:36705998..36706021,+!p2@ZNF146!0.50!41.55!ZNF146;;chr19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| ||
| | |ffid_belonging_in_development=CL:0000049,CL:0000134 | ||
| | |||
| | |||
|fonse_cell_line=FF:0101035 | |fonse_cell_line=FF:0101035 | ||
|fonse_cell_line_closure=FF:0101035 | |fonse_cell_line_closure=FF:0101035 | ||
Line 66: | Line 40: | ||
|fonse_treatment= | |fonse_treatment= | ||
|fonse_treatment_closure= | |fonse_treatment_closure= | ||
|has_quality= | |has_quality= | ||
|is_a=EFO:0002091;;FF: | |hg19bam=http://fantom.gsc.riken.jp/5/datafiles/latest/basic/human.cell_line.hCAGE/acute%2520myeloid%2520leukemia%2520%2528FAB%2520M2%2529%2520cell%2520line%253aKasumi-1.CNhs13502.10788-110H5.hg19.nobarcode.bam | ||
|hg19ctss=http://fantom.gsc.riken.jp/5/datafiles/latest/basic/human.cell_line.hCAGE/acute%2520myeloid%2520leukemia%2520%2528FAB%2520M2%2529%2520cell%2520line%253aKasumi-1.CNhs13502.10788-110H5.hg19.ctss.bed.gz | |||
|hg19fasta=http://fantom.gsc.riken.jp/5/datafiles/latest/basic/human.cell_line.hCAGE/acute%2520myeloid%2520leukemia%2520%2528FAB%2520M2%2529%2520cell%2520line%253aKasumi-1.CNhs13502.10788-110H5.hg19.nobarcode.rdna.fa.gz | |||
|hg38bam=http://fantom.gsc.riken.jp/5/datafiles/reprocessed/hg38_v2/basic/human.cell_line.hCAGE/acute%2520myeloid%2520leukemia%2520%2528FAB%2520M2%2529%2520cell%2520line%253aKasumi-1.CNhs13502.10788-110H5.hg38.nobarcode.bam | |||
|hg38ctss=http://fantom.gsc.riken.jp/5/datafiles/reprocessed/hg38_v2/basic/human.cell_line.hCAGE/acute%2520myeloid%2520leukemia%2520%2528FAB%2520M2%2529%2520cell%2520line%253aKasumi-1.CNhs13502.10788-110H5.hg38.nobarcode.ctss.bed.gz | |||
|id=FF:10788-110H5 | |||
|is_a=EFO:0002091;;FF:0000210;;FF:0101883 | |||
|is_obsolete= | |||
|library_id=CNhs13502 | |||
|library_id_phase_based=2:CNhs13502 | |||
|microRNAs= | |||
|microRNAs_nn= | |||
|microRNAs_nonnovel_cage=http://fantom.gsc.riken.jp/5/suppl/De_Rie_et_al_2017/vis_viewer/#/human#cage;sample;10788 | |||
|microRNAs_novel_cage=http://fantom.gsc.riken.jp/5/suppl/De_Rie_et_al_2017/vis_viewer_novel/#/human#cage;sample;10788 | |||
|name=acute myeloid leukemia (FAB M2) cell line:Kasumi-1 | |||
|namespace=FANTOM5 | |namespace=FANTOM5 | ||
|part_of= | |part_of= | ||
|profile_cagescan=,,, | |||
|profile_hcage=CNhs13502,LSID1025,release012,COMPLETED | |||
|profile_rnaseq= | |||
|profile_srnaseq=,,, | |||
|refex=http://refex.dbcls.jp/genelist.php?lang | |||
|repeat_enrich_byfamily=0,0,0,0,0,0,0,-0.0382260859123901,0,0.141454321456163,0.38001083618335,0,0,0,0,0,0,0,0,0,0,0,0.122091944173996,0,-0.153323010348428,0,0,0,0,0,0.0241340479059385,0,0,0.556837207863413,0,0,0,0,0,0,0,0,0,0,0,0,0.0851015608366818,0.122091944173996,0,0,0,0,0,0,0,-0.0242150211128343,0,0,0,0.893043486838571,0,0,0.122091944173996,0.321824092407072,0,0,-0.097343627213097,0,0,0,0,0,0,0,0,0,0,0.122091944173996,0,0,0.122091944173996,0,0,0,0,0,0,0,0,0,-0.0504125515893149,-0.200966870308956,0,0,0,0.0255472762784867,0.0462327091040758,0.061045972086998,0,0,0,0.0240565929362896,0.341414202416334,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,-0.096373593922461,0,0,0,0.0638909101038396,0.00403795742644695,0,0,0.122091944173996,0,0,0 | |||
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| |||
|rna_box=110 | |||
|rna_catalog_number= | |||
|rna_concentration=0.17814 | |||
|rna_extraction_protocol=OP-RNA-extraction-totalRNA-miRNeasy_Mini-v1.0 | |||
|rna_lot_number= | |||
|rna_od260/230=1.61 | |||
|rna_od260/280=2.04 | |||
|rna_position=H5 | |||
|rna_rin= | |||
|rna_sample_type=total RNA | |||
|rna_tube_id=110H5 | |||
|rna_weight_ug=4.80978 | |||
|sample_age=7 | |||
|sample_category=cell lines | |||
|sample_cell_catalog=jcrb1003 | |||
|sample_cell_line=Kasumi-1 | |||
|sample_cell_lot= | |||
|sample_cell_type=myeloid progenitor cell | |||
|sample_collaboration=FANTOM5 OSC CORE (contact: Al Forrest) | |||
|sample_company=JAPAN HEALTH SCIENCES FOUNDATION - Health Science Research Resources Bank | |||
|sample_description= | |||
|sample_dev_stage= | |||
|sample_disease=acute myeloid leukemia (FAB M2) | |||
|sample_donor(cell lot)= | |||
|sample_ethnicity=J | |||
|sample_experimental_condition= | |||
|sample_gostat=GO:0044464;cell part;0!GO:0005622;intracellular;0!GO:0044424;intracellular part;8.18418452402077e-256!GO:0043227;membrane-bound organelle;1.68564607890622e-226!GO:0043231;intracellular membrane-bound organelle;4.04467362653019e-226!GO:0043226;organelle;1.29716830155552e-210!GO:0043229;intracellular organelle;4.58413776719038e-210!GO:0005737;cytoplasm;3.72617878887729e-168!GO:0044422;organelle part;1.50022867001846e-153!GO:0044446;intracellular organelle part;5.77457425567025e-152!GO:0044444;cytoplasmic part;9.13874068225417e-129!GO:0044237;cellular metabolic process;5.57080198823624e-119!GO:0044238;primary metabolic process;9.93854333924898e-115!GO:0043170;macromolecule metabolic process;3.47009121128408e-105!GO:0032991;macromolecular complex;9.43112767409748e-103!GO:0005634;nucleus;1.46690153554504e-100!GO:0030529;ribonucleoprotein complex;4.08424325060847e-98!GO:0043233;organelle lumen;1.37829143946627e-90!GO:0031974;membrane-enclosed lumen;1.37829143946627e-90!GO:0005739;mitochondrion;1.67771630161948e-87!GO:0044428;nuclear part;3.23018807860163e-87!GO:0003723;RNA binding;4.93393779961337e-87!GO:0006396;RNA processing;1.1858939983624e-64!GO:0043283;biopolymer metabolic process;3.77709392646845e-63!GO:0044429;mitochondrial part;2.47939296810744e-59!GO:0006412;translation;2.77052558716987e-59!GO:0006139;nucleobase, nucleoside, nucleotide and nucleic acid metabolic process;2.79331980101069e-59!GO:0005840;ribosome;1.93266339813621e-58!GO:0010467;gene expression;4.72165599628756e-56!GO:0031981;nuclear lumen;2.96611935747919e-55!GO:0003735;structural constituent of ribosome;1.05959295349547e-51!GO:0019538;protein metabolic process;2.5844472610024e-51!GO:0009058;biosynthetic process;3.62429198975464e-50!GO:0031967;organelle envelope;3.98450361799992e-49!GO:0031975;envelope;1.0095329133578e-48!GO:0043234;protein complex;1.06305922232742e-48!GO:0031090;organelle membrane;1.07998332509824e-48!GO:0044249;cellular biosynthetic process;1.43517363329253e-48!GO:0005515;protein binding;1.53701743569618e-48!GO:0044260;cellular macromolecule metabolic process;1.15512019922905e-47!GO:0009059;macromolecule biosynthetic process;1.40909816925021e-47!GO:0044267;cellular protein metabolic process;2.48636856823929e-47!GO:0016071;mRNA metabolic process;2.55935559176185e-47!GO:0006259;DNA metabolic process;2.12822643958643e-46!GO:0033279;ribosomal subunit;3.30773428428716e-44!GO:0006397;mRNA processing;4.64964304467165e-43!GO:0008380;RNA splicing;5.98235306688833e-43!GO:0033036;macromolecule localization;2.88370055412887e-42!GO:0022613;ribonucleoprotein complex biogenesis and assembly;8.42616442806005e-41!GO:0015031;protein transport;2.78441598115266e-40!GO:0016043;cellular component organization and biogenesis;3.64336879682388e-38!GO:0003676;nucleic acid binding;9.68713706818601e-38!GO:0045184;establishment of protein localization;1.03397084175388e-37!GO:0005740;mitochondrial envelope;1.21036314258749e-37!GO:0008104;protein localization;2.60146955988306e-37!GO:0005829;cytosol;5.26240251016517e-37!GO:0019866;organelle inner membrane;1.90879300274367e-36!GO:0031966;mitochondrial membrane;8.39911447981809e-35!GO:0006996;organelle organization and biogenesis;5.58273581903889e-34!GO:0046907;intracellular transport;1.88112222635577e-33!GO:0005743;mitochondrial inner membrane;2.12196694121867e-33!GO:0065003;macromolecular complex assembly;2.98050498203358e-33!GO:0005654;nucleoplasm;7.39594357051475e-33!GO:0005830;cytosolic ribosome (sensu Eukaryota);1.02191764808461e-31!GO:0000166;nucleotide binding;2.79379424181931e-31!GO:0005681;spliceosome;4.07202826833104e-30!GO:0043228;non-membrane-bound organelle;1.06398374588288e-29!GO:0043232;intracellular non-membrane-bound organelle;1.06398374588288e-29!GO:0006886;intracellular protein transport;4.30273423963957e-29!GO:0007049;cell cycle;8.42181004021004e-29!GO:0022607;cellular component assembly;1.40029859654743e-28!GO:0044445;cytosolic part;6.20171207077399e-27!GO:0016070;RNA metabolic process;1.34217120761884e-26!GO:0031980;mitochondrial lumen;2.99485491893928e-26!GO:0005759;mitochondrial matrix;2.99485491893928e-26!GO:0006974;response to DNA damage stimulus;1.77988944287736e-25!GO:0005694;chromosome;3.16087174837232e-25!GO:0044451;nucleoplasm part;5.70196932755359e-25!GO:0044455;mitochondrial membrane part;1.26343382629359e-24!GO:0051649;establishment of cellular localization;2.3283008885686e-24!GO:0005730;nucleolus;9.50428190824041e-24!GO:0051641;cellular localization;1.08776908984161e-23!GO:0006119;oxidative phosphorylation;1.32875685565573e-23!GO:0006281;DNA repair;6.77118694216137e-23!GO:0006457;protein folding;6.77118694216137e-23!GO:0022402;cell cycle process;8.15630304974264e-23!GO:0051276;chromosome organization and biogenesis;8.79281283450387e-23!GO:0015934;large ribosomal subunit;1.00484549404406e-22!GO:0015935;small ribosomal subunit;1.11562683287301e-22!GO:0044427;chromosomal part;4.2268287479991e-22!GO:0022618;protein-RNA complex assembly;5.32363425209757e-22!GO:0016817;hydrolase activity, acting on acid anhydrides;5.03642986445052e-21!GO:0016818;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides;5.16275262800089e-21!GO:0016462;pyrophosphatase activity;5.16275262800089e-21!GO:0032553;ribonucleotide binding;9.30689241458816e-21!GO:0032555;purine ribonucleotide binding;9.30689241458816e-21!GO:0017076;purine nucleotide binding;1.29514765276788e-20!GO:0000278;mitotic cell cycle;1.42622787224013e-20!GO:0016874;ligase activity;1.88311450298497e-20!GO:0017111;nucleoside-triphosphatase activity;4.72090169892318e-20!GO:0044265;cellular macromolecule catabolic process;6.61847563408958e-20!GO:0042254;ribosome biogenesis and assembly;1.08583554402137e-19!GO:0005524;ATP binding;1.76633777669852e-19!GO:0032559;adenyl ribonucleotide binding;4.99688469445333e-19!GO:0006325;establishment and/or maintenance of chromatin architecture;7.87257322082812e-19!GO:0030554;adenyl nucleotide binding;9.54225112899175e-19!GO:0005746;mitochondrial respiratory chain;2.89212024425386e-18!GO:0006323;DNA packaging;3.53868163264822e-18!GO:0044248;cellular catabolic process;3.85307923759168e-18!GO:0009719;response to endogenous stimulus;5.57102541156158e-18!GO:0008135;translation factor activity, nucleic acid binding;1.41400159038496e-17!GO:0051186;cofactor metabolic process;1.55240288651128e-17!GO:0006512;ubiquitin cycle;1.73705787814152e-17!GO:0006260;DNA replication;5.6017230503059e-17!GO:0043285;biopolymer catabolic process;7.58978421032518e-17!GO:0009057;macromolecule catabolic process;8.1110562943737e-17!GO:0016887;ATPase activity;9.21029688581211e-17!GO:0042623;ATPase activity, coupled;1.28171769084938e-16!GO:0012505;endomembrane system;1.67002108428587e-16!GO:0005842;cytosolic large ribosomal subunit (sensu Eukaryota);1.7184263432893e-16!GO:0005761;mitochondrial ribosome;3.19543872898352e-16!GO:0000313;organellar ribosome;3.19543872898352e-16!GO:0048770;pigment granule;4.23225990494971e-16!GO:0042470;melanosome;4.23225990494971e-16!GO:0050136;NADH dehydrogenase (quinone) activity;5.35694912790862e-16!GO:0003954;NADH dehydrogenase activity;5.35694912790862e-16!GO:0008137;NADH dehydrogenase (ubiquinone) activity;5.35694912790862e-16!GO:0000502;proteasome complex (sensu Eukaryota);5.50692008251689e-16!GO:0016655;oxidoreductase activity, acting on NADH or NADPH, quinone or similar compound as acceptor;5.8266922072505e-16!GO:0022403;cell cycle phase;1.07714791237732e-15!GO:0000398;nuclear mRNA splicing, via spliceosome;1.2027945695175e-15!GO:0000375;RNA splicing, via transesterification reactions;1.2027945695175e-15!GO:0000377;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile;1.2027945695175e-15!GO:0005843;cytosolic small ribosomal subunit (sensu Eukaryota);1.20438358672897e-15!GO:0006605;protein targeting;1.3173520033532e-15!GO:0051082;unfolded protein binding;2.80339981027543e-15!GO:0044453;nuclear membrane part;2.85563340119277e-15!GO:0051603;proteolysis involved in cellular protein catabolic process;2.99429211841043e-15!GO:0051301;cell division;3.38461704737915e-15!GO:0006511;ubiquitin-dependent protein catabolic process;3.59674632183429e-15!GO:0019941;modification-dependent protein catabolic process;4.6573464975301e-15!GO:0043632;modification-dependent macromolecule catabolic process;4.6573464975301e-15!GO:0044257;cellular protein catabolic process;5.94434954802217e-15!GO:0043412;biopolymer modification;6.7577055718711e-15!GO:0004386;helicase activity;7.80258514388373e-15!GO:0000087;M phase of mitotic cell cycle;8.06734563145577e-15!GO:0006732;coenzyme metabolic process;1.13444507030088e-14!GO:0006399;tRNA metabolic process;1.69436244849521e-14!GO:0006413;translational initiation;2.07896925906544e-14!GO:0007067;mitosis;2.27083008956961e-14!GO:0016604;nuclear body;2.46843787359813e-14!GO:0031965;nuclear membrane;3.75992632116949e-14!GO:0042775;organelle ATP synthesis coupled electron transport;3.78687925873645e-14!GO:0042773;ATP synthesis coupled electron transport;3.78687925873645e-14!GO:0003743;translation initiation factor activity;4.33197028997384e-14!GO:0044432;endoplasmic reticulum part;5.35761102704237e-14!GO:0030964;NADH dehydrogenase complex (quinone);5.69772753205931e-14!GO:0045271;respiratory chain complex I;5.69772753205931e-14!GO:0005747;mitochondrial respiratory chain complex I;5.69772753205931e-14!GO:0050657;nucleic acid transport;9.17520399527321e-14!GO:0051236;establishment of RNA localization;9.17520399527321e-14!GO:0050658;RNA transport;9.17520399527321e-14!GO:0000785;chromatin;1.306333885849e-13!GO:0006403;RNA localization;1.58092490396864e-13!GO:0016568;chromatin modification;1.58092490396864e-13!GO:0006913;nucleocytoplasmic transport;1.65209172663528e-13!GO:0006364;rRNA processing;1.73333438138946e-13!GO:0008134;transcription factor binding;1.77842380682355e-13!GO:0006120;mitochondrial electron transport, NADH to ubiquinone;1.9653053475681e-13!GO:0006446;regulation of translational initiation;2.0696510438679e-13!GO:0016072;rRNA metabolic process;4.0328602975984e-13!GO:0051169;nuclear transport;4.16853089864316e-13!GO:0005783;endoplasmic reticulum;6.88814676967712e-13!GO:0008026;ATP-dependent helicase activity;8.97245214963558e-13!GO:0006464;protein modification process;9.4757566353925e-13!GO:0051726;regulation of cell cycle;9.56212212736964e-13!GO:0005643;nuclear pore;9.57701122080162e-13!GO:0000074;regulation of progression through cell cycle;1.18370194832706e-12!GO:0005635;nuclear envelope;1.25119269442064e-12!GO:0030163;protein catabolic process;2.4158562042846e-12!GO:0016651;oxidoreductase activity, acting on NADH or NADPH;2.58991935245209e-12!GO:0009259;ribonucleotide metabolic process;2.72908188911865e-12!GO:0006163;purine nucleotide metabolic process;3.1901465707132e-12!GO:0000279;M phase;4.48403280197571e-12!GO:0006164;purine nucleotide biosynthetic process;5.06924891566776e-12!GO:0015931;nucleobase, nucleoside, nucleotide and nucleic acid transport;5.39820159226512e-12!GO:0016607;nuclear speck;6.17198441783467e-12!GO:0051028;mRNA transport;6.98090101439184e-12!GO:0009260;ribonucleotide biosynthetic process;1.13437512648481e-11!GO:0006333;chromatin assembly or disassembly;1.21619723346695e-11!GO:0065002;intracellular protein transport across a membrane;1.2569175094565e-11!GO:0016787;hydrolase activity;1.34123270311297e-11!GO:0048193;Golgi vesicle transport;2.11294226129701e-11!GO:0009056;catabolic process;3.93738011625231e-11!GO:0051188;cofactor biosynthetic process;5.56227789577223e-11!GO:0008565;protein transporter activity;5.60088394072529e-11!GO:0009150;purine ribonucleotide metabolic process;6.86263500394642e-11!GO:0046930;pore complex;8.09870538935969e-11!GO:0046961;hydrogen ion transporting ATPase activity, rotational mechanism;1.01284355346618e-10!GO:0009152;purine ribonucleotide biosynthetic process;1.11957154110648e-10!GO:0043687;post-translational protein modification;1.31075745661722e-10!GO:0042175;nuclear envelope-endoplasmic reticulum network;1.49160482449576e-10!GO:0009055;electron carrier activity;1.53703035106078e-10!GO:0017038;protein import;2.90832622050837e-10!GO:0005789;endoplasmic reticulum membrane;3.73138335765574e-10!GO:0016740;transferase activity;5.42618082472202e-10!GO:0016779;nucleotidyltransferase activity;5.47437741808689e-10!GO:0016876;ligase activity, forming aminoacyl-tRNA and related compounds;6.73337010989409e-10!GO:0004812;aminoacyl-tRNA ligase activity;6.73337010989409e-10!GO:0016875;ligase activity, forming carbon-oxygen bonds;6.73337010989409e-10!GO:0055086;nucleobase, nucleoside and nucleotide metabolic process;1.12472950315036e-09!GO:0046933;hydrogen ion transporting ATP synthase activity, rotational mechanism;1.12472950315036e-09!GO:0065004;protein-DNA complex assembly;1.13769845938924e-09!GO:0043038;amino acid activation;1.1448322379149e-09!GO:0006418;tRNA aminoacylation for protein translation;1.1448322379149e-09!GO:0043039;tRNA aminoacylation;1.1448322379149e-09!GO:0016192;vesicle-mediated transport;1.39105493694058e-09!GO:0019829;cation-transporting ATPase activity;2.03702210595526e-09!GO:0016879;ligase activity, forming carbon-nitrogen bonds;2.14351378297012e-09!GO:0008639;small protein conjugating enzyme activity;5.44872949701081e-09!GO:0009060;aerobic respiration;6.80529606023641e-09!GO:0003712;transcription cofactor activity;6.90927869694978e-09!GO:0016591;DNA-directed RNA polymerase II, holoenzyme;7.11262756322064e-09!GO:0012501;programmed cell death;7.44867250428017e-09!GO:0006915;apoptosis;7.6890359739214e-09!GO:0009142;nucleoside triphosphate biosynthetic process;8.00629834278962e-09!GO:0009201;ribonucleoside triphosphate biosynthetic process;8.00629834278962e-09!GO:0015986;ATP synthesis coupled proton transport;8.20778342427921e-09!GO:0015985;energy coupled proton transport, down electrochemical gradient;8.20778342427921e-09!GO:0007005;mitochondrion organization and biogenesis;1.11856865806203e-08!GO:0009199;ribonucleoside triphosphate metabolic process;1.20094917115864e-08!GO:0009141;nucleoside triphosphate metabolic process;1.23207969214432e-08!GO:0004842;ubiquitin-protein ligase activity;1.27630295262568e-08!GO:0009108;coenzyme biosynthetic process;1.42291301706685e-08!GO:0009117;nucleotide metabolic process;1.66902767457932e-08!GO:0005794;Golgi apparatus;1.7549057653389e-08!GO:0009206;purine ribonucleoside triphosphate biosynthetic process;1.80598211062198e-08!GO:0009145;purine nucleoside triphosphate biosynthetic process;1.80598211062198e-08!GO:0019787;small conjugating protein ligase activity;2.18138824884235e-08!GO:0043566;structure-specific DNA binding;2.56534615146954e-08!GO:0009205;purine ribonucleoside triphosphate metabolic process;2.58825925359587e-08!GO:0009144;purine nucleoside triphosphate metabolic process;2.58825925359587e-08!GO:0006461;protein complex assembly;5.51918544752933e-08!GO:0030532;small nuclear ribonucleoprotein complex;5.57365952849937e-08!GO:0006261;DNA-dependent DNA replication;6.38240680581926e-08!GO:0006754;ATP biosynthetic process;7.22906307763108e-08!GO:0006753;nucleoside phosphate metabolic process;7.22906307763108e-08!GO:0045333;cellular respiration;7.32743862221481e-08!GO:0006334;nucleosome assembly;9.78962040163023e-08!GO:0008219;cell death;1.05958251197426e-07!GO:0016265;death;1.05958251197426e-07!GO:0015078;hydrogen ion transmembrane transporter activity;1.0980197412924e-07!GO:0046034;ATP metabolic process;1.46685326391615e-07!GO:0031497;chromatin assembly;1.76384929252328e-07!GO:0045259;proton-transporting ATP synthase complex;2.01105058485081e-07!GO:0016469;proton-transporting two-sector ATPase complex;2.04217961903571e-07!GO:0006366;transcription from RNA polymerase II promoter;2.04217961903571e-07!GO:0016491;oxidoreductase activity;2.05580799674483e-07!GO:0003697;single-stranded DNA binding;2.17058928964319e-07!GO:0016881;acid-amino acid ligase activity;2.22304077006233e-07!GO:0005793;ER-Golgi intermediate compartment;2.26505029582301e-07!GO:0000775;chromosome, pericentric region;2.41733486414574e-07!GO:0006752;group transfer coenzyme metabolic process;2.63376560600164e-07!GO:0051329;interphase of mitotic cell cycle;3.2938738298974e-07!GO:0051170;nuclear import;3.29879792439061e-07!GO:0006084;acetyl-CoA metabolic process;3.85990928217091e-07!GO:0006099;tricarboxylic acid cycle;4.03169600694738e-07!GO:0046356;acetyl-CoA catabolic process;4.03169600694738e-07!GO:0000245;spliceosome assembly;4.42753033959002e-07!GO:0003899;DNA-directed RNA polymerase activity;5.18502052490746e-07!GO:0006793;phosphorus metabolic process;5.24494865231754e-07!GO:0006796;phosphate metabolic process;5.24494865231754e-07!GO:0051246;regulation of protein metabolic process;5.41988552656308e-07!GO:0051325;interphase;6.61979442614669e-07!GO:0006606;protein import into nucleus;8.33958522904766e-07!GO:0008094;DNA-dependent ATPase activity;8.52652885461271e-07!GO:0005813;centrosome;1.42483078898548e-06!GO:0005839;proteasome core complex (sensu Eukaryota);1.42483078898548e-06!GO:0005819;spindle;1.51132897944104e-06!GO:0050794;regulation of cellular process;1.86750577357155e-06!GO:0009109;coenzyme catabolic process;1.9609155973217e-06!GO:0043623;cellular protein complex assembly;2.35754503809667e-06!GO:0031202;RNA splicing factor activity, transesterification mechanism;2.49037062475495e-06!GO:0003724;RNA helicase activity;2.7932900468979e-06!GO:0000075;cell cycle checkpoint;2.80412665472542e-06!GO:0003713;transcription coactivator activity;3.26813285976382e-06!GO:0019222;regulation of metabolic process;3.43430467804198e-06!GO:0051168;nuclear export;3.68556481398001e-06!GO:0016853;isomerase activity;3.68556481398001e-06!GO:0016741;transferase activity, transferring one-carbon groups;3.68556481398001e-06!GO:0005815;microtubule organizing center;4.19739088569505e-06!GO:0006888;ER to Golgi vesicle-mediated transport;4.39578613184241e-06!GO:0007051;spindle organization and biogenesis;4.39578613184241e-06!GO:0016310;phosphorylation;4.45183169962716e-06!GO:0032446;protein modification by small protein conjugation;4.53018710797905e-06!GO:0042981;regulation of apoptosis;4.68537396262572e-06!GO:0005667;transcription factor complex;4.98888104704275e-06!GO:0008033;tRNA processing;5.10629013480236e-06!GO:0008168;methyltransferase activity;5.15643445703957e-06!GO:0004298;threonine endopeptidase activity;6.15002185356343e-06!GO:0043067;regulation of programmed cell death;6.43437171254291e-06!GO:0005657;replication fork;7.50717953126431e-06!GO:0005768;endosome;8.21648759261078e-06!GO:0000314;organellar small ribosomal subunit;8.51189754846206e-06!GO:0005763;mitochondrial small ribosomal subunit;8.51189754846206e-06!GO:0003682;chromatin binding;9.04479697260133e-06!GO:0006091;generation of precursor metabolites and energy;9.15454152971903e-06!GO:0044452;nucleolar part;9.43071676071426e-06!GO:0016567;protein ubiquitination;9.55541196955766e-06!GO:0003678;DNA helicase activity;9.71114487888851e-06!GO:0009165;nucleotide biosynthetic process;9.83048627398977e-06!GO:0015077;monovalent inorganic cation transmembrane transporter activity;9.88783472365699e-06!GO:0006613;cotranslational protein targeting to membrane;1.20498928559335e-05!GO:0005762;mitochondrial large ribosomal subunit;1.23778022188363e-05!GO:0000315;organellar large ribosomal subunit;1.23778022188363e-05!GO:0006310;DNA recombination;1.39427507239615e-05!GO:0003690;double-stranded DNA binding;1.67519534754935e-05!GO:0042625;ATPase activity, coupled to transmembrane movement of ions;1.82389554351954e-05!GO:0016363;nuclear matrix;1.88004564785054e-05!GO:0051187;cofactor catabolic process;2.10080864861597e-05!GO:0006401;RNA catabolic process;2.1421005799938e-05!GO:0005773;vacuole;2.19984649579237e-05!GO:0005788;endoplasmic reticulum lumen;2.42589728318109e-05!GO:0006839;mitochondrial transport;2.42589728318109e-05!GO:0048475;coated membrane;2.4328602903069e-05!GO:0030117;membrane coat;2.4328602903069e-05!GO:0003729;mRNA binding;2.54370146240196e-05!GO:0015630;microtubule cytoskeleton;2.69155125790938e-05!GO:0016772;transferase activity, transferring phosphorus-containing groups;2.94121057809792e-05!GO:0015405;P-P-bond-hydrolysis-driven transmembrane transporter activity;3.07404221459967e-05!GO:0015399;primary active transmembrane transporter activity;3.07404221459967e-05!GO:0000323;lytic vacuole;3.30827600200456e-05!GO:0005764;lysosome;3.30827600200456e-05!GO:0045786;negative regulation of progression through cell cycle;3.60302127558619e-05!GO:0003755;peptidyl-prolyl cis-trans isomerase activity;3.95212038744134e-05!GO:0030120;vesicle coat;4.14702778771726e-05!GO:0030662;coated vesicle membrane;4.14702778771726e-05!GO:0030530;heterogeneous nuclear ribonucleoprotein complex;4.46678450202645e-05!GO:0005852;eukaryotic translation initiation factor 3 complex;4.66868945697172e-05!GO:0008654;phospholipid biosynthetic process;4.71571417293268e-05!GO:0051427;hormone receptor binding;5.04241672149027e-05!GO:0000151;ubiquitin ligase complex;5.06270944777349e-05!GO:0016859;cis-trans isomerase activity;5.35088734101902e-05!GO:0043021;ribonucleoprotein binding;5.38986270931529e-05!GO:0045454;cell redox homeostasis;6.61683604389225e-05!GO:0006302;double-strand break repair;7.25110276631703e-05!GO:0005753;mitochondrial proton-transporting ATP synthase complex;7.57181649137971e-05!GO:0006405;RNA export from nucleus;7.76634169679934e-05!GO:0004518;nuclease activity;9.01313442173001e-05!GO:0000786;nucleosome;9.01313442173001e-05!GO:0019752;carboxylic acid metabolic process;9.39730063373744e-05!GO:0006082;organic acid metabolic process;9.65159012512232e-05!GO:0043681;protein import into mitochondrion;9.86812605201529e-05!GO:0007006;mitochondrial membrane organization and biogenesis;9.91275739174403e-05!GO:0006916;anti-apoptosis;9.96499465640334e-05!GO:0008186;RNA-dependent ATPase activity;0.000103709254170948!GO:0016765;transferase activity, transferring alkyl or aryl (other than methyl) groups;0.000108230785936875!GO:0035257;nuclear hormone receptor binding;0.000109803684891921!GO:0031323;regulation of cellular metabolic process;0.000116268027556117!GO:0006626;protein targeting to mitochondrion;0.000119204759436421!GO:0048523;negative regulation of cellular process;0.000122288243798494!GO:0030880;RNA polymerase complex;0.000124748118362248!GO:0065009;regulation of a molecular function;0.000155280244770659!GO:0016563;transcription activator activity;0.000155512669592527!GO:0015980;energy derivation by oxidation of organic compounds;0.000155593292845289!GO:0006414;translational elongation;0.000160510110216911!GO:0016281;eukaryotic translation initiation factor 4F complex;0.00018105003094743!GO:0031324;negative regulation of cellular metabolic process;0.000190276886707493!GO:0005798;Golgi-associated vesicle;0.000225987240877869!GO:0006520;amino acid metabolic process;0.000228742503144446!GO:0044262;cellular carbohydrate metabolic process;0.000267567444640702!GO:0015992;proton transport;0.000273762222225596!GO:0006818;hydrogen transport;0.000282765359356967!GO:0032508;DNA duplex unwinding;0.000305262065294628!GO:0032392;DNA geometric change;0.000305262065294628!GO:0006383;transcription from RNA polymerase III promoter;0.000305677300872526!GO:0055029;nuclear DNA-directed RNA polymerase complex;0.000311888372957347!GO:0000428;DNA-directed RNA polymerase complex;0.000311888372957347!GO:0005885;Arp2/3 protein complex;0.000313414716355545!GO:0006402;mRNA catabolic process;0.000315272593167975!GO:0031968;organelle outer membrane;0.000316591050694624!GO:0004004;ATP-dependent RNA helicase activity;0.000316591050694624!GO:0043069;negative regulation of programmed cell death;0.000336205408498043!GO:0000776;kinetochore;0.000352595661724805!GO:0000059;protein import into nucleus, docking;0.000360833774847566!GO:0019867;outer membrane;0.000404888445994035!GO:0005525;GTP binding;0.000415404800700764!GO:0043066;negative regulation of apoptosis;0.000419616236862108!GO:0004527;exonuclease activity;0.00045830485741696!GO:0007059;chromosome segregation;0.000459975255947905!GO:0045261;proton-transporting ATP synthase complex, catalytic core F(1);0.00048573567818392!GO:0033178;proton-transporting two-sector ATPase complex, catalytic domain;0.000511913276403311!GO:0046483;heterocycle metabolic process;0.00052173704108585!GO:0050662;coenzyme binding;0.000528668098670766!GO:0005769;early endosome;0.000549297257680371!GO:0006350;transcription;0.000601679295433924!GO:0030384;phosphoinositide metabolic process;0.000604436667538168!GO:0044431;Golgi apparatus part;0.000619739923859182!GO:0045934;negative regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process;0.000626170553967517!GO:0031072;heat shock protein binding;0.000633443374785794!GO:0045263;proton-transporting ATP synthase complex, coupling factor F(o);0.000637165469771282!GO:0033177;proton-transporting two-sector ATPase complex, proton-transporting domain;0.000637165469771282!GO:0043492;ATPase activity, coupled to movement of substances;0.000674841279926745!GO:0019899;enzyme binding;0.000674951519463806!GO:0000082;G1/S transition of mitotic cell cycle;0.000684306861348694!GO:0000049;tRNA binding;0.000696862049308509!GO:0003684;damaged DNA binding;0.000706909609594039!GO:0006612;protein targeting to membrane;0.000706909609594039!GO:0016564;transcription repressor activity;0.000745869499851505!GO:0005741;mitochondrial outer membrane;0.000795039788372774!GO:0046474;glycerophospholipid biosynthetic process;0.000825345005958035!GO:0005770;late endosome;0.000827769319265851!GO:0016679;oxidoreductase activity, acting on diphenols and related substances as donors;0.000836352055663625!GO:0016681;oxidoreductase activity, acting on diphenols and related substances as donors, cytochrome as acceptor;0.000836352055663625!GO:0008121;ubiquinol-cytochrome-c reductase activity;0.000836352055663625!GO:0016820;hydrolase activity, acting on acid anhydrides, catalyzing transmembrane movement of substances;0.00084178775876797!GO:0051052;regulation of DNA metabolic process;0.00084178775876797!GO:0006338;chromatin remodeling;0.000848507803900861!GO:0006268;DNA unwinding during replication;0.000857778388308823!GO:0042626;ATPase activity, coupled to transmembrane movement of substances;0.000872549737449697!GO:0005637;nuclear inner membrane;0.000872666968759536!GO:0030867;rough endoplasmic reticulum membrane;0.000882916655122317!GO:0006650;glycerophospholipid metabolic process;0.00092820961140203!GO:0005684;U2-dependent spliceosome;0.00104423027215284!GO:0006950;response to stress;0.00109884795613336!GO:0008757;S-adenosylmethionine-dependent methyltransferase activity;0.00111853806496706!GO:0009124;nucleoside monophosphate biosynthetic process;0.00116826130252027!GO:0009123;nucleoside monophosphate metabolic process;0.00116826130252027!GO:0048500;signal recognition particle;0.00127688312080074!GO:0007052;mitotic spindle organization and biogenesis;0.00127853687415181!GO:0050789;regulation of biological process;0.00128782877452956!GO:0005048;signal sequence binding;0.00135225963704864!GO:0048519;negative regulation of biological process;0.00143585883325441!GO:0051087;chaperone binding;0.00144679481642655!GO:0006144;purine base metabolic process;0.00148843226373083!GO:0046489;phosphoinositide biosynthetic process;0.00151465813875598!GO:0000079;regulation of cyclin-dependent protein kinase activity;0.00152179667283906!GO:0006352;transcription initiation;0.00152179667283906!GO:0016251;general RNA polymerase II transcription factor activity;0.00159488972353229!GO:0008312;7S RNA binding;0.00162727051834759!GO:0003711;transcription elongation regulator activity;0.00164671073491243!GO:0007088;regulation of mitosis;0.00172435630960707!GO:0051252;regulation of RNA metabolic process;0.00177265964623581!GO:0004003;ATP-dependent DNA helicase activity;0.00200798048616657!GO:0005838;proteasome regulatory particle (sensu Eukaryota);0.00205035407029515!GO:0031124;mRNA 3'-end processing;0.00207432899363825!GO:0000287;magnesium ion binding;0.00207432899363825!GO:0031988;membrane-bound vesicle;0.00212092414297739!GO:0044440;endosomal part;0.0021968343774839!GO:0010008;endosome membrane;0.0021968343774839!GO:0016197;endosome transport;0.00220106499896278!GO:0043284;biopolymer biosynthetic process;0.00235341900386987!GO:0010468;regulation of gene expression;0.00243401237374175!GO:0005996;monosaccharide metabolic process;0.00247730794682564!GO:0007050;cell cycle arrest;0.00255103629550747!GO:0009892;negative regulation of metabolic process;0.00255863593235802!GO:0009161;ribonucleoside monophosphate metabolic process;0.00269407509470517!GO:0009156;ribonucleoside monophosphate biosynthetic process;0.00269407509470517!GO:0000178;exosome (RNase complex);0.00274624433949061!GO:0006890;retrograde vesicle-mediated transport, Golgi to ER;0.00287720817059657!GO:0019318;hexose metabolic process;0.00292198283193244!GO:0051789;response to protein stimulus;0.0030442514685886!GO:0006986;response to unfolded protein;0.0030442514685886!GO:0043123;positive regulation of I-kappaB kinase/NF-kappaB cascade;0.0030442514685886!GO:0006417;regulation of translation;0.00308958159441626!GO:0043122;regulation of I-kappaB kinase/NF-kappaB cascade;0.00319379309968055!GO:0007093;mitotic cell cycle checkpoint;0.00320611505976821!GO:0006519;amino acid and derivative metabolic process;0.00325998863848516!GO:0006614;SRP-dependent cotranslational protein targeting to membrane;0.00330748544460816!GO:0045047;protein targeting to ER;0.00330748544460816!GO:0006595;polyamine metabolic process;0.003313583737272!GO:0009112;nucleobase metabolic process;0.0033176564961564!GO:0005758;mitochondrial intermembrane space;0.00338925864953769!GO:0016272;prefoldin complex;0.00348928841916881!GO:0005786;signal recognition particle, endoplasmic reticulum targeting;0.00360040391080569!GO:0008276;protein methyltransferase activity;0.00360534774280415!GO:0032561;guanyl ribonucleotide binding;0.0037476811927602!GO:0019001;guanyl nucleotide binding;0.0037476811927602!GO:0051287;NAD binding;0.00385805553347449!GO:0031982;vesicle;0.00398167887661882!GO:0006406;mRNA export from nucleus;0.00398167887661882!GO:0042393;histone binding;0.00422641476115822!GO:0006270;DNA replication initiation;0.00425702827449032!GO:0016023;cytoplasmic membrane-bound vesicle;0.00428152801275626!GO:0048037;cofactor binding;0.00428152801275626!GO:0016676;oxidoreductase activity, acting on heme group of donors, oxygen as acceptor;0.0045146303205997!GO:0015002;heme-copper terminal oxidase activity;0.0045146303205997!GO:0016675;oxidoreductase activity, acting on heme group of donors;0.0045146303205997!GO:0004129;cytochrome-c oxidase activity;0.0045146303205997!GO:0016481;negative regulation of transcription;0.00455361363152185!GO:0006378;mRNA polyadenylation;0.00481493685562084!GO:0051539;4 iron, 4 sulfur cluster binding;0.00503714049038936!GO:0000922;spindle pole;0.00503714049038936!GO:0006891;intra-Golgi vesicle-mediated transport;0.00508726566950077!GO:0006497;protein amino acid lipidation;0.00508726566950077!GO:0007021;tubulin folding;0.00510194594359831!GO:0007249;I-kappaB kinase/NF-kappaB cascade;0.00517147987585769!GO:0031123;RNA 3'-end processing;0.00528431844629972!GO:0035258;steroid hormone receptor binding;0.00539483179836682!GO:0005665;DNA-directed RNA polymerase II, core complex;0.00565842206908828!GO:0008632;apoptotic program;0.00573329299625468!GO:0050790;regulation of catalytic activity;0.00577612988427063!GO:0019219;regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process;0.00582240574185184!GO:0019843;rRNA binding;0.00596247229272227!GO:0006357;regulation of transcription from RNA polymerase II promoter;0.00619270095163337!GO:0006506;GPI anchor biosynthetic process;0.00623339843621601!GO:0031570;DNA integrity checkpoint;0.00624972652907354!GO:0043596;nuclear replication fork;0.00627647757351887!GO:0006289;nucleotide-excision repair;0.00644760841516548!GO:0051920;peroxiredoxin activity;0.00645663871642694!GO:0009451;RNA modification;0.00652320322814651!GO:0003924;GTPase activity;0.00653965711831149!GO:0009081;branched chain family amino acid metabolic process;0.00669822393843633!GO:0003887;DNA-directed DNA polymerase activity;0.00679733919869613!GO:0005876;spindle microtubule;0.00682744916403127!GO:0006007;glucose catabolic process;0.00697121905374792!GO:0006779;porphyrin biosynthetic process;0.00699747915151019!GO:0033014;tetrapyrrole biosynthetic process;0.00699747915151019!GO:0008139;nuclear localization sequence binding;0.00707941618854296!GO:0016126;sterol biosynthetic process;0.00709172914537691!GO:0000139;Golgi membrane;0.00714512741860259!GO:0043022;ribosome binding;0.00714904636988433!GO:0042802;identical protein binding;0.00745032269849172!GO:0032200;telomere organization and biogenesis;0.00745032269849172!GO:0000723;telomere maintenance;0.00745032269849172!GO:0016862;intramolecular oxidoreductase activity, interconverting keto- and enol-groups;0.00746919243801309!GO:0006505;GPI anchor metabolic process;0.0076349300097858!GO:0048487;beta-tubulin binding;0.0076349300097858!GO:0005669;transcription factor TFIID complex;0.00767557647120558!GO:0016407;acetyltransferase activity;0.00767557647120558!GO:0030663;COPI coated vesicle membrane;0.00769168698928104!GO:0030126;COPI vesicle coat;0.00769168698928104!GO:0003714;transcription corepressor activity;0.00792489507013003!GO:0031410;cytoplasmic vesicle;0.00794722203566286!GO:0004532;exoribonuclease activity;0.00801433303809428!GO:0016896;exoribonuclease activity, producing 5'-phosphomonoesters;0.00801433303809428!GO:0000339;RNA cap binding;0.00815399528481578!GO:0022890;inorganic cation transmembrane transporter activity;0.00828290018016376!GO:0031326;regulation of cellular biosynthetic process;0.00840761669453572!GO:0006284;base-excision repair;0.00855968509286672!GO:0043488;regulation of mRNA stability;0.00859841700743315!GO:0043487;regulation of RNA stability;0.00859841700743315!GO:0005832;chaperonin-containing T-complex;0.00882644426656287!GO:0016891;endoribonuclease activity, producing 5'-phosphomonoesters;0.00902762873243756!GO:0016893;endonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters;0.00910990975777968!GO:0006733;oxidoreduction coenzyme metabolic process;0.00911707302094209!GO:0006220;pyrimidine nucleotide metabolic process;0.00918417922748745!GO:0000118;histone deacetylase complex;0.00921574121558424!GO:0030176;integral to endoplasmic reticulum membrane;0.00929322862871896!GO:0009116;nucleoside metabolic process;0.00948490461321575!GO:0016627;oxidoreductase activity, acting on the CH-CH group of donors;0.00969167816080216!GO:0007034;vacuolar transport;0.00970678862820233!GO:0006695;cholesterol biosynthetic process;0.00981559132947253!GO:0005975;carbohydrate metabolic process;0.00985196436046554!GO:0051540;metal cluster binding;0.0100151809349588!GO:0051536;iron-sulfur cluster binding;0.0100151809349588!GO:0051053;negative regulation of DNA metabolic process;0.0100359247107325!GO:0000096;sulfur amino acid metabolic process;0.0101273373596116!GO:0000228;nuclear chromosome;0.0101327636203493!GO:0043161;proteasomal ubiquitin-dependent protein catabolic process;0.0101619730786347!GO:0006740;NADPH regeneration;0.0107210712562143!GO:0006098;pentose-phosphate shunt;0.0107210712562143!GO:0009127;purine nucleoside monophosphate biosynthetic process;0.0107512606836385!GO:0009167;purine ribonucleoside monophosphate metabolic process;0.0107512606836385!GO:0009126;purine nucleoside monophosphate metabolic process;0.0107512606836385!GO:0009168;purine ribonucleoside monophosphate biosynthetic process;0.0107512606836385!GO:0006807;nitrogen compound metabolic process;0.0107590750986515!GO:0016408;C-acyltransferase activity;0.0108335945535417!GO:0043065;positive regulation of apoptosis;0.0109428303870476!GO:0031970;organelle envelope lumen;0.0109783591801177!GO:0006611;protein export from nucleus;0.0112420888392728!GO:0006730;one-carbon compound metabolic process;0.0112470889366093!GO:0008610;lipid biosynthetic process;0.0114308923963358!GO:0046467;membrane lipid biosynthetic process;0.0115135080699711!GO:0003746;translation elongation factor activity;0.0118822944547998!GO:0009303;rRNA transcription;0.0120162888310654!GO:0043414;biopolymer methylation;0.0120654170679212!GO:0035267;NuA4 histone acetyltransferase complex;0.0120745084151677!GO:0030137;COPI-coated vesicle;0.0121479397212161!GO:0004540;ribonuclease activity;0.0122452323502988!GO:0007007;inner mitochondrial membrane organization and biogenesis;0.0124687811138809!GO:0004674;protein serine/threonine kinase activity;0.0127824556370896!GO:0033116;ER-Golgi intermediate compartment membrane;0.0127824556370896!GO:0042158;lipoprotein biosynthetic process;0.0128177449637273!GO:0047485;protein N-terminus binding;0.0130206835290563!GO:0006118;electron transport;0.0130397828098334!GO:0000184;mRNA catabolic process, nonsense-mediated decay;0.0133055205746475!GO:0006376;mRNA splice site selection;0.0134588094735746!GO:0000389;nuclear mRNA 3'-splice site recognition;0.0134588094735746!GO:0048471;perinuclear region of cytoplasm;0.0134862079437748!GO:0008097;5S rRNA binding;0.0135092057647532!GO:0045045;secretory pathway;0.0135092057647532!GO:0015036;disulfide oxidoreductase activity;0.0135489049585639!GO:0043068;positive regulation of programmed cell death;0.0135489049585639!GO:0043189;H4/H2A histone acetyltransferase complex;0.0135489049585639!GO:0009308;amine metabolic process;0.0135489049585639!GO:0008320;protein transmembrane transporter activity;0.0138013619058224!GO:0022884;macromolecule transmembrane transporter activity;0.0141641851721504!GO:0015450;P-P-bond-hydrolysis-driven protein transmembrane transporter activity;0.0141641851721504!GO:0032259;methylation;0.0143005210383328!GO:0006672;ceramide metabolic process;0.014915160260724!GO:0046983;protein dimerization activity;0.0150440573038874!GO:0030658;transport vesicle membrane;0.0153227685455657!GO:0030145;manganese ion binding;0.0154270617510206!GO:0004576;oligosaccharyl transferase activity;0.0156098634914274!GO:0000726;non-recombinational repair;0.0157145419762489!GO:0032774;RNA biosynthetic process;0.0158469887828023!GO:0005850;eukaryotic translation initiation factor 2 complex;0.0158469887828023!GO:0006275;regulation of DNA replication;0.0159414969656594!GO:0015631;tubulin binding;0.0160472356714293!GO:0032981;mitochondrial respiratory chain complex I assembly;0.0163397497875069!GO:0010257;NADH dehydrogenase complex assembly;0.0163397497875069!GO:0033108;mitochondrial respiratory chain complex assembly;0.0163397497875069!GO:0008250;oligosaccharyl transferase complex;0.0163397497875069!GO:0003677;DNA binding;0.0165122914177714!GO:0008652;amino acid biosynthetic process;0.0177644975577682!GO:0046519;sphingoid metabolic process;0.0181124843319263!GO:0046966;thyroid hormone receptor binding;0.0181869629495214!GO:0003725;double-stranded RNA binding;0.0181885115432231!GO:0000792;heterochromatin;0.0182342361437691!GO:0006351;transcription, DNA-dependent;0.018376761795425!GO:0022411;cellular component disassembly;0.018595120814574!GO:0016584;nucleosome positioning;0.0186698056912151!GO:0000077;DNA damage checkpoint;0.0187368227500589!GO:0004579;dolichyl-diphosphooligosaccharide-protein glycotransferase activity;0.0191215563216987!GO:0000781;chromosome, telomeric region;0.0191215563216987!GO:0019377;glycolipid catabolic process;0.0194339256700364!GO:0046365;monosaccharide catabolic process;0.0195081546734419!GO:0006767;water-soluble vitamin metabolic process;0.0198269890545863!GO:0046479;glycosphingolipid catabolic process;0.0203519734292222!GO:0043631;RNA polyadenylation;0.0203944452518958!GO:0030134;ER to Golgi transport vesicle;0.0207479255246582!GO:0000725;recombinational repair;0.0213889367685974!GO:0000724;double-strand break repair via homologous recombination;0.0213889367685974!GO:0008538;proteasome activator activity;0.021527236604723!GO:0008234;cysteine-type peptidase activity;0.0215702157325175!GO:0004177;aminopeptidase activity;0.022139377546647!GO:0030521;androgen receptor signaling pathway;0.0224260286854079!GO:0006379;mRNA cleavage;0.0224734022765799!GO:0007040;lysosome organization and biogenesis;0.0226771686314715!GO:0009067;aspartate family amino acid biosynthetic process;0.0227793838055785!GO:0032984;macromolecular complex disassembly;0.0230628207510116!GO:0006643;membrane lipid metabolic process;0.0230822971513982!GO:0008408;3'-5' exonuclease activity;0.0234279618139524!GO:0045947;negative regulation of translational initiation;0.0234279618139524!GO:0008144;drug binding;0.0236205086209349!GO:0019206;nucleoside kinase activity;0.023733493637607!GO:0051098;regulation of binding;0.0237618992070985!GO:0046128;purine ribonucleoside metabolic process;0.023876715770966!GO:0042278;purine nucleoside metabolic process;0.023876715770966!GO:0030433;ER-associated protein catabolic process;0.023919208537399!GO:0006515;misfolded or incompletely synthesized protein catabolic process;0.023919208537399!GO:0044438;microbody part;0.023919208537399!GO:0044439;peroxisomal part;0.023919208537399!GO:0007243;protein kinase cascade;0.024367929767514!GO:0016279;protein-lysine N-methyltransferase activity;0.0248706856699862!GO:0018024;histone-lysine N-methyltransferase activity;0.0248706856699862!GO:0016278;lysine N-methyltransferase activity;0.0248706856699862!GO:0030041;actin filament polymerization;0.0248706856699862!GO:0030660;Golgi-associated vesicle membrane;0.0248706856699862!GO:0003756;protein disulfide isomerase activity;0.0248706856699862!GO:0016864;intramolecular oxidoreductase activity, transposing S-S bonds;0.0248706856699862!GO:0032603;fractalkine production;0.0248706856699862!GO:0050725;positive regulation of interleukin-1 beta biosynthetic process;0.0248706856699862!GO:0050752;regulation of fractalkine biosynthetic process;0.0248706856699862!GO:0045362;positive regulation of interleukin-1 biosynthetic process;0.0248706856699862!GO:0050754;positive regulation of fractalkine biosynthetic process;0.0248706856699862!GO:0001774;microglial cell activation;0.0248706856699862!GO:0050756;fractalkine metabolic process;0.0248706856699862!GO:0005766;primary lysosome;0.0248706856699862!GO:0050751;fractalkine biosynthetic process;0.0248706856699862!GO:0042222;interleukin-1 biosynthetic process;0.0248706856699862!GO:0050722;regulation of interleukin-1 beta biosynthetic process;0.0248706856699862!GO:0045360;regulation of interleukin-1 biosynthetic process;0.0248706856699862!GO:0042582;azurophil granule;0.0248706856699862!GO:0050720;interleukin-1 beta biosynthetic process;0.0248706856699862!GO:0030127;COPII vesicle coat;0.0248706856699862!GO:0012507;ER to Golgi transport vesicle membrane;0.0248706856699862!GO:0016788;hydrolase activity, acting on ester bonds;0.0249964888466994!GO:0015923;mannosidase activity;0.0250289200017891!GO:0016018;cyclosporin A binding;0.0251357829923696!GO:0000910;cytokinesis;0.0251620321810535!GO:0042770;DNA damage response, signal transduction;0.025253938428337!GO:0051338;regulation of transferase activity;0.0254149354295854!GO:0042054;histone methyltransferase activity;0.0255778924405431!GO:0046164;alcohol catabolic process;0.0256446897912708!GO:0000123;histone acetyltransferase complex;0.0262113486277735!GO:0009066;aspartate family amino acid metabolic process;0.0263466160274401!GO:0005791;rough endoplasmic reticulum;0.0266812677241296!GO:0006778;porphyrin metabolic process;0.0269449958806624!GO:0033013;tetrapyrrole metabolic process;0.0269449958806624!GO:0005652;nuclear lamina;0.0269919943818686!GO:0000175;3'-5'-exoribonuclease activity;0.0271565295918408!GO:0043549;regulation of kinase activity;0.0272307718093479!GO:0004722;protein serine/threonine phosphatase activity;0.0272633691394157!GO:0016569;covalent chromatin modification;0.0277499523316764!GO:0005869;dynactin complex;0.0277738129121275!GO:0016860;intramolecular oxidoreductase activity;0.0280638380202453!GO:0043241;protein complex disassembly;0.028074456414428!GO:0030118;clathrin coat;0.0280782692168081!GO:0003923;GPI-anchor transamidase activity;0.028121501336018!GO:0016255;attachment of GPI anchor to protein;0.028121501336018!GO:0042765;GPI-anchor transamidase complex;0.028121501336018!GO:0019783;small conjugating protein-specific protease activity;0.0281668708371265!GO:0008022;protein C-terminus binding;0.0288101817416085!GO:0046112;nucleobase biosynthetic process;0.0289079662544597!GO:0006066;alcohol metabolic process;0.02927895795434!GO:0006783;heme biosynthetic process;0.0293071740267411!GO:0000819;sister chromatid segregation;0.0300785172352714!GO:0050178;phenylpyruvate tautomerase activity;0.0300785172352714!GO:0000226;microtubule cytoskeleton organization and biogenesis;0.0302580033543412!GO:0000070;mitotic sister chromatid segregation;0.0302580033543412!GO:0019320;hexose catabolic process;0.0302580033543412!GO:0016667;oxidoreductase activity, acting on sulfur group of donors;0.0303961296116423!GO:0006596;polyamine biosynthetic process;0.030523191501477!GO:0006400;tRNA modification;0.030523191501477!GO:0031903;microbody membrane;0.030591126211392!GO:0005778;peroxisomal membrane;0.030591126211392!GO:0009083;branched chain family amino acid catabolic process;0.030591126211392!GO:0009889;regulation of biosynthetic process;0.0306377405509958!GO:0031577;spindle checkpoint;0.0306900321375133!GO:0032940;secretion by cell;0.0307534801011015!GO:0008287;protein serine/threonine phosphatase complex;0.0310470348412711!GO:0006266;DNA ligation;0.0310791850991169!GO:0009113;purine base biosynthetic process;0.0311748418084057!GO:0016790;thiolester hydrolase activity;0.0315259686012399!GO:0030132;clathrin coat of coated pit;0.0315927989183448!GO:0003988;acetyl-CoA C-acyltransferase activity;0.031819349114288!GO:0006607;NLS-bearing substrate import into nucleus;0.0320749859960184!GO:0006979;response to oxidative stress;0.032117580275742!GO:0043601;nuclear replisome;0.0324922106977302!GO:0030894;replisome;0.0324922106977302!GO:0000152;nuclear ubiquitin ligase complex;0.0337380675110379!GO:0006769;nicotinamide metabolic process;0.0343803561002592!GO:0006917;induction of apoptosis;0.0347135510687086!GO:0004843;ubiquitin-specific protease activity;0.0352239729719672!GO:0018196;peptidyl-asparagine modification;0.0352239729719672!GO:0018279;protein amino acid N-linked glycosylation via asparagine;0.0352239729719672!GO:0008156;negative regulation of DNA replication;0.035229667838693!GO:0030518;steroid hormone receptor signaling pathway;0.0357142039943686!GO:0006516;glycoprotein catabolic process;0.0357480076341223!GO:0006509;membrane protein ectodomain proteolysis;0.0362032368813918!GO:0033619;membrane protein proteolysis;0.0362032368813918!GO:0006301;postreplication repair;0.0366559449043662!GO:0007041;lysosomal transport;0.0371176414593937!GO:0042719;mitochondrial intermembrane space protein transporter complex;0.0373649556844503!GO:0045039;protein import into mitochondrial inner membrane;0.0373649556844503!GO:0003857;3-hydroxyacyl-CoA dehydrogenase activity;0.0376581794100042!GO:0030149;sphingolipid catabolic process;0.0385053348486897!GO:0005092;GDP-dissociation inhibitor activity;0.0396228300786617!GO:0016780;phosphotransferase activity, for other substituted phosphate groups;0.040617897078286!GO:0005744;mitochondrial inner membrane presequence translocase complex;0.0406417401001006!GO:0006518;peptide metabolic process;0.0414470561403539!GO:0004448;isocitrate dehydrogenase activity;0.0415487788209062!GO:0006635;fatty acid beta-oxidation;0.0417188560414693!GO:0031647;regulation of protein stability;0.0417352812808474!GO:0045859;regulation of protein kinase activity;0.0419142922748445!GO:0006356;regulation of transcription from RNA polymerase I promoter;0.0422981653784377!GO:0012502;induction of programmed cell death;0.042519018011918!GO:0044454;nuclear chromosome part;0.0425702793726538!GO:0004239;methionyl aminopeptidase activity;0.0429479353977709!GO:0016311;dephosphorylation;0.0429479353977709!GO:0006367;transcription initiation from RNA polymerase II promoter;0.0429479353977709!GO:0045449;regulation of transcription;0.0429479353977709!GO:0022415;viral reproductive process;0.0432938784874063!GO:0007033;vacuole organization and biogenesis;0.0433529981927733!GO:0000097;sulfur amino acid biosynthetic process;0.0436823374083301!GO:0007004;telomere maintenance via telomerase;0.0439583148900459!GO:0002763;positive regulation of myeloid leukocyte differentiation;0.0440715587971077!GO:0006644;phospholipid metabolic process;0.044236731723388!GO:0006555;methionine metabolic process;0.0444673907827825!GO:0051059;NF-kappaB binding;0.0446736580032536!GO:0016796;exonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters;0.0447312519565746!GO:0017134;fibroblast growth factor binding;0.0451788303888123!GO:0030133;transport vesicle;0.04558134684125!GO:0008047;enzyme activator activity;0.0458282640287464!GO:0040029;regulation of gene expression, epigenetic;0.0459071801400701!GO:0005663;DNA replication factor C complex;0.0463854425584461!GO:0030508;thiol-disulfide exchange intermediate activity;0.0468021884017836!GO:0042769;DNA damage response, detection of DNA damage;0.0471138218843353!GO:0003702;RNA polymerase II transcription factor activity;0.047449738316798!GO:0022406;membrane docking;0.0474654234111302!GO:0048278;vesicle docking;0.0474654234111302!GO:0004300;enoyl-CoA hydratase activity;0.0475415962122746!GO:0032039;integrator complex;0.0478855240298172!GO:0050681;androgen receptor binding;0.0483196332029611!GO:0016791;phosphoric monoester hydrolase activity;0.0484818261360722!GO:0004659;prenyltransferase activity;0.0484818261360722!GO:0009396;folic acid and derivative biosynthetic process;0.0486975262624594!GO:0004221;ubiquitin thiolesterase activity;0.049117006737229!GO:0043624;cellular protein complex disassembly;0.0493389850935297!GO:0008629;induction of apoptosis by intracellular signals;0.0494729432536835!GO:0030119;AP-type membrane coat adaptor complex;0.0499707215357129 | |||
|sample_id=10788 | |||
|sample_note= | |||
|sample_sex=male | |||
|sample_species=Human (Homo sapiens) | |||
|sample_strain= | |||
|sample_tissue=blood | |||
|top_motifs=MYB:1.82704963719;ARNT_ARNT2_BHLHB2_MAX_MYC_USF1:1.4335273445;ALX1:1.37159163859;ZBTB16:1.31766274203;E2F1..5:1.30368852188;PITX1..3:1.29363408264;FOXQ1:1.25809531449;HIF1A:1.19132682975;CUX2:1.13609330267;bHLH_family:1.07752680743;HES1:1.06032790961;PAX8:1.04553067059;FOXD3:0.967759618711;YY1:0.949062410156;TEF:0.878461721501;IKZF2:0.755087176259;NKX2-2,8:0.749586245426;SPIB:0.733955598927;POU1F1:0.717869936511;RXR{A,B,G}_{NR1H2,PPAR}dimers:0.704861116268;NRF1:0.696024307608;PRRX1,2:0.680386660242;NR5A1,2:0.643178298609;GATA6:0.580739197247;DMAP1_NCOR{1,2}_SMARC:0.58022040769;PAX4:0.578799309744;CDX1,2,4:0.548312117768;BREu{core}:0.532066265656;SPI1:0.50384118154;ELF1,2,4:0.461616986586;NFY{A,B,C}:0.453128823154;ONECUT1,2:0.430427506151;CRX:0.417336632189;PBX1:0.388071413339;POU2F1..3:0.359473027254;HOX{A4,D4}:0.347074240561;FOXA2:0.320773380493;MYOD1:0.306694406236;FOX{I1,J2}:0.292749109241;PPARG:0.278936854664;RXR{A,B,G}:0.275384610027;GCM1,2:0.254497747558;ZNF143:0.252665184886;FOXP1:0.221991304313;NANOG{mouse}:0.219447512527;ZNF384:0.214865067282;NR6A1:0.194989458204;HOX{A6,A7,B6,B7}:0.17119297152;STAT5{A,B}:0.170966559094;ETS1,2:0.169076083177;RUNX1..3:0.162911037967;RORA:0.161911643177;FOXM1:0.109597206116;AR:0.0980194106877;NANOG:0.0926331928776;NFIL3:0.0914716723282;ARID5B:0.0871012385416;AIRE:0.0708437664122;TOPORS:0.0614345856309;REST:0.0588345962256;PAX5:0.0571590929151;OCT4_SOX2{dimer}:-0.00768894382981;ZEB1:-0.0102144385865;NKX2-1,4:-0.0129279404143;GZF1:-0.0137267092179;DBP:-0.0140138535165;HAND1,2:-0.018984371015;VSX1,2:-0.033800569545;NKX2-3_NKX2-5:-0.0373544982679;HOXA9_MEIS1:-0.0535374595111;FOXN1:-0.0652922711118;BPTF:-0.070025009937;PAX2:-0.0830058752315;LHX3,4:-0.11182316797;NKX6-1,2:-0.124487669791;SNAI1..3:-0.134342379439;KLF4:-0.135723027985;HSF1,2:-0.145366287069;HOX{A5,B5}:-0.148781548611;RXRA_VDR{dimer}:-0.184554754034;POU5F1:-0.225613625366;HNF1A:-0.232400350993;UFEwm:-0.239259161889;STAT1,3:-0.248382868516;NKX3-2:-0.254473396075;ELK1,4_GABP{A,B1}:-0.269096624297;MEF2{A,B,C,D}:-0.292443128158;HBP1_HMGB_SSRP1_UBTF:-0.317966664711;FOXP3:-0.329782533476;HNF4A_NR2F1,2:-0.33291669187;SOX17:-0.337991449115;NFKB1_REL_RELA:-0.342861403163;ATF5_CREB3:-0.355218860061;TFDP1:-0.357296831703;SOX2:-0.368954228435;SOX5:-0.3772745893;ZFP161:-0.382684289034;NHLH1,2:-0.392020941839;SOX{8,9,10}:-0.395680079153;AHR_ARNT_ARNT2:-0.415405595178;XBP1:-0.430412658434;PRDM1:-0.431626356162;NFIX:-0.438663391547;GFI1:-0.439650891075;CREB1:-0.441871190556;FOX{F1,F2,J1}:-0.443610100038;TGIF1:-0.444974965562;TLX2:-0.449959410926;ZNF238:-0.466219155526;POU6F1:-0.471412742871;ZIC1..3:-0.479191650613;RBPJ:-0.487079590748;MYBL2:-0.492595680245;FOSL2:-0.497027976042;PAX6:-0.504576123289;CEBPA,B_DDIT3:-0.50500083935;POU3F1..4:-0.520059637702;HLF:-0.532737453203;TAL1_TCF{3,4,12}:-0.547944305763;HMGA1,2:-0.558881790315;PAX1,9:-0.566188138368;LEF1_TCF7_TCF7L1,2:-0.575050728948;NFE2:-0.581736777793;RFX2..5_RFXANK_RFXAP:-0.585820628751;PDX1:-0.609373816503;FOS_FOS{B,L1}_JUN{B,D}:-0.619178559947;EVI1:-0.619574960175;CDC5L:-0.627581355157;BACH2:-0.647811267891;EP300:-0.649476024612;ESRRA:-0.655649114785;MYFfamily:-0.656127647437;MZF1:-0.656287482866;ZBTB6:-0.656787959839;IRF1,2:-0.665476822638;ALX4:-0.669549443028;NKX3-1:-0.675374616333;IRF7:-0.68329038545;GATA4:-0.728498256237;HIC1:-0.745214675504;EN1,2:-0.745244143243;ESR1:-0.748604761275;ADNP_IRX_SIX_ZHX:-0.807779589873;ZNF423:-0.816556156909;RFX1:-0.833980114457;MAFB:-0.845680929488;NR1H4:-0.856755188274;FOXL1:-0.871368178606;IKZF1:-0.887461912845;TBP:-0.900267650351;PAX3,7:-0.903716547879;TEAD1:-0.982733492678;SMAD1..7,9:-0.989901835985;NFE2L2:-1.02400012828;TFAP4:-1.02591142499;LMO2:-1.04820561813;ATF4:-1.07063335593;TLX1..3_NFIC{dimer}:-1.07808584751;ZNF148:-1.07917277904;GTF2I:-1.11826055469;MTF1:-1.12301643277;MED-1{core}:-1.12550013222;FOX{D1,D2}:-1.12614381482;TP53:-1.14753690759;RREB1:-1.18043745749;SREBF1,2:-1.19347739343;PATZ1:-1.20235298043;NFE2L1:-1.23547772692;T:-1.23741790082;TFAP2{A,C}:-1.26304115684;STAT2,4,6:-1.26719993318;TFAP2B:-1.27803573645;SRF:-1.28951762388;ATF6:-1.29042112745;TBX4,5:-1.34094585096;ATF2:-1.36924020815;EGR1..3:-1.40697016846;HMX1:-1.40698745975;FOXO1,3,4:-1.41048240531;MAZ:-1.4719940271;EBF1:-1.49711810986;XCPE1{core}:-1.53863886279;SP1:-1.54155638342;GTF2A1,2:-1.55840339805;MTE{core}:-1.57835981461;SPZ1:-1.59958361786;JUN:-1.66391869723;NR3C1:-1.67531521665;NFATC1..3:-1.68132759058;GFI1B:-1.73667855718;TFCP2:-1.77489218129;GLI1..3:-1.88502505423 | |||
|xref= | |||
|zenbu_report=https://fantom.gsc.riken.jp/zenbu/reports/#miRNA_expression_atlas_human;search_select_hide=table111:FF:10788-110H5;search_select_hide=table117:FF:10788-110H5 | |||
}} | }} |
Latest revision as of 15:04, 3 June 2020
Name: | acute myeloid leukemia (FAB M2) cell line:Kasumi-1 |
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Species: | Human (Homo sapiens) |
Library ID: | CNhs13502 |
Sample type: | cell lines |
Genomic View: | UCSC |
RefEX: | Specific genes |
CAGEd-oPOSSUM: | link |
ZENBU report : | link |
Additional information | ||||||||||||||||||||||||||||
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Sample information
RNA information
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CAGE Accession numbers | ||||||||||||||||||||||||||||||||||||||||||||||
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Download raw sequence, BAM & CTSS | ||||||||||||||
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Relative expression to median (log10)
Transcription factors with enriched expression in this sampleRanked list of transcription factor promoter expression in this sample relative to the median expression in the FANTOM5 collection is shown. Value is log10 transformed.
Co-expression clusters with enriched expression in this sampleRanked list of co-expression cluster expression in this sample relative to the median expression in the FANTOM5 collection is shown. Value is log10 transformed. <br>Analyst:NA <br><br>link to dataset.<br>data
Repeat families with enriched expression in this sample<b>Summary:</b>Ranked list of repeat family expression in this sample relative tothe median expression in the FANTOM5 collection is shown. Value is log10transformed.<br><b>Analyst:</b>NA<br><br>link to dataset.<br>data
TFBS(DNA)motifs over-represented in proximal region of promoters active in this sample
JASPAR motifs<b>Summary:</b>Association of JASPAR motif to the promoter expression in thissample. Pearson's correlation between the number of TFBSs estimated byusing the position-weight matrix for each promoter and its expression isexpressed as Z-score by taking the ones based on random position-weightmatrix, and the tail probability of the normal distribution correspondingto the Z-score is taken as the resulting P-value. Lower P-value indicatesmore (non-random) association of the motif to promoter expression<br><b>Analyst:</b> Michiel de Hoon <br><br><br>link to dataset.<br>data
library id: CNhs13502
FANTOM5 phase1 novel unique motifs<b>Summary:</b>Association of the 169 novel and unique motifs discovered in FANTOM5 phase1 in this sample. Among the de-novo motifs discovered by DMF, HOMER,ChIPMunk, and ScanAll, only novel motifs are selected after comparison with known motif sets, and their clustering based on MACRO-APE resulted in169 novel and unique motifs. Their association to the promoter expression is evaluated in the same way to the JASPAR motif above<br><b>Analyst:</b> Michiel de Hoon <br><br><br>link to dataset.<br>data
library id: CNhs13502
Novel motif | Logo | P-value |
---|---|---|
1 | 1 | 0.0884 |
10 | 10 | 0.0163 |
100 | 100 | 0.342 |
101 | 101 | 0.19 |
102 | 102 | 0.455 |
103 | 103 | 0.605 |
104 | 104 | 0.702 |
105 | 105 | 0.232 |
106 | 106 | 0.474 |
107 | 107 | 0.165 |
108 | 108 | 0.863 |
109 | 109 | 0.0702 |
11 | 11 | 0.0508 |
110 | 110 | 0.138 |
111 | 111 | 0.0101 |
112 | 112 | 0.261 |
113 | 113 | 0.715 |
114 | 114 | 0.0055 |
115 | 115 | 0.435 |
116 | 116 | 0.201 |
117 | 117 | 0.0342 |
118 | 118 | 0.027 |
119 | 119 | 0.772 |
12 | 12 | 0.586 |
120 | 120 | 0.134 |
121 | 121 | 0.833 |
122 | 122 | 0.662 |
123 | 123 | 0.00617 |
124 | 124 | 0.169 |
125 | 125 | 0.259 |
126 | 126 | 0.0871 |
127 | 127 | 0.0421 |
128 | 128 | 0.992 |
129 | 129 | 0.29 |
13 | 13 | 0.0076 |
130 | 130 | 0.613 |
131 | 131 | 0.298 |
132 | 132 | 0.824 |
133 | 133 | 0.814 |
134 | 134 | 0.548 |
135 | 135 | 0.92 |
136 | 136 | 0.102 |
137 | 137 | 0.251 |
138 | 138 | 0.651 |
139 | 139 | 0.12 |
14 | 14 | 0.592 |
140 | 140 | 0.193 |
141 | 141 | 0.215 |
142 | 142 | 0.0706 |
143 | 143 | 0.67 |
144 | 144 | 0.859 |
145 | 145 | 0.735 |
146 | 146 | 0.948 |
147 | 147 | 0.192 |
148 | 148 | 0.0404 |
149 | 149 | 0.454 |
15 | 15 | 0.273 |
150 | 150 | 0.97 |
151 | 151 | 0.566 |
152 | 152 | 0.135 |
153 | 153 | 0.977 |
154 | 154 | 0.918 |
155 | 155 | 0.0336 |
156 | 156 | 0.981 |
157 | 157 | 0.301 |
158 | 158 | 0.478 |
159 | 159 | 0.674 |
16 | 16 | 0.673 |
160 | 160 | 0.0896 |
161 | 161 | 0.0993 |
162 | 162 | 0.13 |
163 | 163 | 0.344 |
164 | 164 | 0.0348 |
165 | 165 | 0.516 |
166 | 166 | 0.199 |
167 | 167 | 0.00919 |
168 | 168 | 0.164 |
169 | 169 | 0.468 |
17 | 17 | 0.801 |
18 | 18 | 0.734 |
19 | 19 | 0.781 |
2 | 2 | 0.568 |
20 | 20 | 0.335 |
21 | 21 | 0.0363 |
22 | 22 | 0.979 |
23 | 23 | 0.149 |
24 | 24 | 0.226 |
25 | 25 | 0.279 |
26 | 26 | 0.0209 |
27 | 27 | 0.532 |
28 | 28 | 0.978 |
29 | 29 | 0.0431 |
3 | 3 | 0.169 |
30 | 30 | 0.0787 |
31 | 31 | 0.379 |
32 | 32 | 0.349 |
33 | 33 | 0.737 |
34 | 34 | 0.706 |
35 | 35 | 0.158 |
36 | 36 | 0.0388 |
37 | 37 | 0.389 |
38 | 38 | 0.826 |
39 | 39 | 0.579 |
4 | 4 | 0.065 |
40 | 40 | 0.334 |
41 | 41 | 0.702 |
42 | 42 | 0.246 |
43 | 43 | 0.496 |
44 | 44 | 0.115 |
45 | 45 | 0.575 |
46 | 46 | 0.0985 |
47 | 47 | 0.0417 |
48 | 48 | 0.0499 |
49 | 49 | 0.272 |
5 | 5 | 0.982 |
50 | 50 | 0.952 |
51 | 51 | 0.856 |
52 | 52 | 0.189 |
53 | 53 | 0.512 |
54 | 54 | 0.51 |
55 | 55 | 0.369 |
56 | 56 | 0.969 |
57 | 57 | 0.00562 |
58 | 58 | 0.255 |
59 | 59 | 0.517 |
6 | 6 | 0.328 |
60 | 60 | 0.975 |
61 | 61 | 0.121 |
62 | 62 | 0.151 |
63 | 63 | 0.485 |
64 | 64 | 0.231 |
65 | 65 | 0.491 |
66 | 66 | 0.0813 |
67 | 67 | 0.744 |
68 | 68 | 0.413 |
69 | 69 | 0.325 |
7 | 7 | 0.0587 |
70 | 70 | 0.424 |
71 | 71 | 0.0357 |
72 | 72 | 0.858 |
73 | 73 | 0.987 |
74 | 74 | 0.552 |
75 | 75 | 0.0163 |
76 | 76 | 0.0882 |
77 | 77 | 0.725 |
78 | 78 | 0.0147 |
79 | 79 | 0.166 |
8 | 8 | 0.048 |
80 | 80 | 0.204 |
81 | 81 | 0.121 |
82 | 82 | 0.267 |
83 | 83 | 0.521 |
84 | 84 | 0.299 |
85 | 85 | 0.605 |
86 | 86 | 0.609 |
87 | 87 | 0.504 |
88 | 88 | 0.471 |
89 | 89 | 0.606 |
9 | 9 | 0.825 |
90 | 90 | 0.00348 |
91 | 91 | 0.784 |
92 | 92 | 0.857 |
93 | 93 | 0.726 |
94 | 94 | 0.583 |
95 | 95 | 0.129 |
96 | 96 | 0.593 |
97 | 97 | 0.366 |
98 | 98 | 0.175 |
99 | 99 | 0.508 |
de novo motifs identified by HOMER in promoters active in this sample<b>Summary:</b>The result of HOMER in this sample is shown.<br><b>Analyst:</b>NA <br>
library id: CNhs13502
FANTOM5 (FF) ontology
Direct parent terms
is_a relathionship
EFO:0002091 biological replicate
FF:0000210 human sample
FF:0101883 acute myeloid leukemia cell line sample
Ancestor terms (non development)<b>Summary:</b>Connected ontology terms with is_a, part_of or located_in relationship <br><b>Analyst:</b> Hideya Kawaji<br><br>link to source data<br>data
CL: Cell type
0000000 (cell), 0000000 (cell)
0000003 (native cell)
0000988 (hematopoietic cell)
0000548 (animal cell)
0000763 (myeloid cell)
0002371 (somatic cell)
0000255 (eukaryotic cell)
DOID: Disease
4 (disease)
0050686 (organ system cancer)
162 (cancer)
2531 (hematologic cancer)
14566 (disease of cellular proliferation)
0060083 (immune system cancer)
1240 (leukemia)
8692 (myeloid leukemia)
FF: FANTOM5
0000102 (sample by type)
0000003 (cell line sample)
0000210 (human sample)
0000101 (sample by species)
0000001 (sample)
0100737 (leukemia cell line sample)
0101035 (hematopoietic cell line sample)
0101883 (acute myeloid leukemia cell line sample)
0100740 (myeloid leukemia cell line sample)
Ancestor terms (development)<b>Summary:</b>Connected ontology terms with develops_from, derives_from or preceded_by relationship <br><b>Analyst:</b> Hideya Kawaji <br><br>link to source data<br>data
CL:0000049 (common myeloid progenitor)
CL:0000134 (mesenchymal cell)