FF:10831-111D3: Difference between revisions
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{{f5samples | {{f5samples | ||
| | |DRA_sample_Accession=CAGE@SAMD00005714 | ||
| | |accession_numbers=CAGE;DRX007808;DRR008680;DRZ000105;DRZ001490;DRZ011455;DRZ012840 | ||
| | |ancestors_in_anatomy_facet= | ||
| | |ancestors_in_cell_lineage_facet=CL:0000000,CL:0000003,CL:0000988,CL:0000548,CL:0000763,CL:0002371,CL:0000255 | ||
| | |ancestors_in_disease_facet=DOID:4,DOID:0050686,DOID:162,DOID:2531,DOID:14566,DOID:0060083,DOID:1240,DOID:8692 | ||
|ancestors_in_ff_facet=FF:0000102,FF:0000003,FF:0000210,FF:0000101,FF:0000001,FF:0100737,FF:0101035,FF:0101883,FF:0100740 | |||
| | |comment= | ||
|created_by= | |||
|creation_date= | |||
|data_phase=2 | |||
| | |datafreeze_phase=2 | ||
| | |def= | ||
| | |expression_enrichment_score=chr20:31350184..31350200,+!p1@DNMT3B!1.91!163.71!DNMT3B;;chr21:39870339..39870443,-!p1@ERG!1.89!75.84!ERG;;chr7:27205136..27205164,-!p1@HOXA9!1.88!74.83!HOXA9;;chr20:62680984..62680999,-!p1@SOX18!1.78!77.54!SOX18;;chr12:54694758..54694805,-!p1@NFE2!1.76!67.72!NFE2;;chr1:25291475..25291511,-!p2@RUNX3!1.74!54.17!RUNX3;;chr11:47400078..47400106,-!p1@SPI1!1.66!44.35!SPI1;;chr2:16080659..16080685,+!p1@MYCN!1.64!42.32!MYCN;;chr19:13213511..13213545,-!p2@LYL1!1.62!43.68!LYL1;;chr12:54694807..54694832,-!p3@NFE2!1.61!40.12!NFE2;;chr2:68592406..68592424,+!p1@PLEK!1.60!38.43!PLEK;;chr9:135854091..135854159,+!p1@GFI1B!1.55!34.70!GFI1B;;chr6:135502501..135502546,+!p1@MYB!1.54!39.78!MYB;;chr19:33793430..33793447,-!p1@CEBPA!1.52!131.71!CEBPA;;chr12:54778471..54778528,-!p1@ZNF385A!1.48!29.29!ZNF385A;;chr17:40441354..40441410,+!p2@STAT5A!1.47!28.44!STAT5A;;chr19:13213662..13213686,-!p1@LYL1!1.45!39.95!LYL1;;chr2:16082155..16082169,+!p3@MYCN!1.45!27.09!MYCN;;chr12:54785074..54785122,-!p2@ZNF385A!1.44!39.95!ZNF385A;;chr5:88178983..88179012,-!p1@MEF2C!1.41!184.36!MEF2C;;chr7:50344289..50344323,+!p1@IKZF1!1.38!22.85!IKZF1;;chr12:96588368..96588394,+!p3@ELK3!1.35!56.20!ELK3;;chr11:47399996..47400014,-!p4@SPI1!1.35!21.50!SPI1;;chr7:115670804..115670825,-!p1@TFEC!1.35!21.16!TFEC;;chr7:27213893..27213954,-!p1@HOXA10!1.33!20.32!HOXA10;;chr9:20382446..20382493,-!p4@MLLT3!1.33!20.15!MLLT3;;chr12:54785054..54785072,-!p4@ZNF385A!1.32!22.69!ZNF385A;;chr7:27205106..27205134,-!p2@HOXA9!1.32!19.81!HOXA9;;chrX:2418949..2419024,-!p1@DHRSX,p1@ZBED1!1.30!18.96!ZBED1;;chr4:57522598..57522664,-!p3@HOPX!1.30!18.96!HOPX;;chr11:47399947..47399961,-!p3@SPI1!1.30!18.79!SPI1;;chr6:15401104..15401166,+!p5@JARID2!1.28!17.94!JARID2;;chr4:57522513..57522548,-!p4@HOPX!1.27!17.78!HOPX;;chr8:60031619..60031676,-!p1@TOX!1.24!35.38!TOX;;chr6:135502408..135502459,+!p2@MYB!1.24!18.96!MYB;;chr7:27192185..27192209,-!p1@HOXA3!1.24!16.42!HOXA3;;chr7:137620650..137620677,-!p3@CREB3L2!1.22!15.74!CREB3L2;;chr18:77155922..77155939,+!p1@NFATC1!1.20!39.95!NFATC1;;chr20:50159198..50159299,-!p1@NFATC2!1.16!19.81!NFATC2;;chr3:128206762..128206781,-!p2@GATA2!1.15!80.92!GATA2;;chr14:75988771..75988826,+!p1@BATF!1.15!17.44!BATF;;chr3:18486354..18486377,-!p2@SATB1!1.15!16.42!SATB1;;chr2:68592394..68592405,+!p2@PLEK!1.13!12.36!PLEK;;chr11:47400062..47400077,-!p2@SPI1!1.13!12.36!SPI1;;chr2:172949484..172949522,+!p1@DLX1!1.09!11.34!DLX1;;chr18:22932080..22932170,-!p1@ZNF521!1.06!44.52!ZNF521;;chr1:25256756..25256774,-!p1@RUNX3!1.06!19.64!RUNX3;;chr3:128212033..128212051,-!p1@GATA2!1.06!10.50!GATA2;;chr8:60031563..60031574,-!p7@TOX!1.06!10.50!TOX;;chr10:94449703..94449718,+!p1@HHEX!1.05!40.29!HHEX;;chr11:47279504..47279563,+!p1@NR1H3!1.05!23.36!NR1H3;;chr3:141747459..141747475,-!p1@TFDP2!1.04!84.98!TFDP2;;chr9:117150254..117150271,-!p1@AKNA!1.03!27.26!AKNA;;chr19:12203100..12203132,+!p1@ZNF788!1.03!19.81!ZNF788;;chr12:11802547..11802560,+!p5@ETV6!1.02!13.20!ETV6;;chr3:168865194..168865245,-!p3@MECOM!1.02!12.36!MECOM;;chr16:88752861..88752884,-!p2@SNAI3!1.02!9.48!SNAI3;;chr2:25475120..25475176,-!p2@DNMT3A!1.01!12.70!DNMT3A;;chr7:50348268..50348366,+!p4@IKZF1!1.01!9.14!IKZF1;;chr5:88179017..88179046,-!p2@MEF2C!1.00!36.74!MEF2C;;chr2:66662281..66662308,+!p1@MEIS1!1.00!31.49!MEIS1;;chr1:3569072..3569093,+!p1@TP73!1.00!8.97!TP73;;chr8:60031534..60031553,-!p8@TOX!0.97!8.30!TOX;;chr2:60780607..60780624,-!p2@BCL11A!0.96!25.73!BCL11A;;chr17:41623692..41623715,-!p1@ETV4!0.95!35.21!ETV4;;chr11:47400032..47400043,-!p5@SPI1!0.95!7.96!SPI1;;chr10:94449675..94449694,+!p2@HHEX!0.94!21.16!HHEX;;chr4:57522674..57522699,-!p5@HOPX!0.94!7.79!HOPX;;chr1:92951607..92951661,-!p1@GFI1!0.94!7.62!GFI1;;chr7:137620684..137620711,-!p4@CREB3L2!0.94!7.62!CREB3L2;;chr19:22817119..22817145,+!p1@ZNF492!0.93!12.70!ZNF492;;chr6:135502472..135502489,+!p3@MYB!0.93!7.45!MYB;;chr3:141747441..141747452,-!p4@TFDP2!0.92!10.50!TFDP2;;chr3:168865250..168865272,-!p5@MECOM!0.92!7.28!MECOM;;chr7:27224842..27224872,-!p1@HOXA11!0.92!7.28!HOXA11;;chr1:47691303..47691319,-!p5@TAL1!0.91!7.11!TAL1;;chr1:221052776..221052799,+!p1@HLX!0.90!12.87!HLX;;chr19:13213555..13213568,-!p5@LYL1!0.90!6.94!LYL1;;chr7:50344251..50344288,+!p3@IKZF1!0.90!6.94!IKZF1;;chr5:321810..321877,+!p1@AHRR!0.89!22.69!AHRR;;chr2:16081912..16081931,+!p2@MYCN!0.89!6.77!MYCN;;chr7:149470641..149470694,-!p1@ZNF467!0.88!30.98!ZNF467;;chr19:20011744..20011770,+!p1@ZNF93!0.87!26.07!ZNF93;;chr17:41277372..41277418,-!p1@BRCA1!0.87!24.55!BRCA1;;chr2:214014959..214015006,-!p4@IKZF2!0.87!6.43!IKZF2;;chr1:92949331..92949377,-!p2@GFI1!0.86!6.26!GFI1;;chr13:41593425..41593480,-!p1@ELF1!0.85!41.31!ELF1;;chr12:54694653..54694672,-!p2@NFE2!0.84!5.93!NFE2;;chr1:25291620..25291635,-!p4@RUNX3!0.84!5.93!RUNX3;;chr12:11802600..11802685,+!p1@ETV6!0.83!94.63!ETV6;;chr17:46622205..46622218,-!p3@HOXB2!0.83!6.77!HOXB2;;chr7:50343634..50343717,+!p2@IKZF1!0.83!5.76!IKZF1;;chr13:36871902..36872023,-!p1@CCDC169-SOHLH2,p1@CCDC169,p1@SOHLH2!0.82!12.87!SOHLH2;;chr1:23857698..23857733,-!p1@E2F2!0.81!10.33!E2F2;;chr3:168864315..168864339,-!p2@MECOM!0.81!9.31!MECOM;;chr11:47400045..47400060,-!p6@SPI1!0.81!5.42!SPI1;;chr17:46675420..46675465,-!p3@HOXB6!0.80!6.26!HOXB6;;chr6:144385698..144385742,-!p2@PLAGL1!0.79!6.43!PLAGL1;;chr1:221052994..221053008,+!p6@HLX!0.79!6.26!HLX;;chr8:145669791..145669834,-!p1@TONSL!0.78!15.41!TONSL;;chr14:89628064..89628109,-!p4@FOXN3!0.78!11.00!FOXN3;;chr3:71355163..71355209,-!p5@FOXP1!0.78!7.28!FOXP1;;chr4:57522166..57522260,-!p2@HOPX!0.78!5.93!HOPX;;chr2:25475094..25475112,-!p3@DNMT3A!0.78!5.08!DNMT3A;;chr21:34442439..34442455,+!p1@OLIG1!0.78!5.08!OLIG1;;chr18:22932004..22932021,-!p2@ZNF521!0.78!5.08!ZNF521;;chr2:63277948..63277974,+!p1@OTX1!0.77!4.91!OTX1;;chr13:100634004..100634025,+!p2@ZIC2!0.77!4.91!ZIC2;;chr8:116681409..116681431,-!p2@TRPS1!0.76!13.88!TRPS1;;chr19:22034809..22034878,-!p2@ZNF43!0.75!17.78!ZNF43;;chr7:27196217..27196246,-!p2@HOXA7!0.75!4.57!HOXA7;;chr22:21771656..21771662,+!p1@HIC2!0.75!4.57!HIC2;;chr17:40440481..40440550,+!p1@STAT5A!0.73!35.38!STAT5A;;chr14:74226961..74227020,-!p1@C14orf43!0.73!32.00!C14orf43;;chr17:46622070..46622109,-!p1@HOXB2!0.73!10.50!HOXB2;;chr21:40177845..40177863,+!p1@ETS2!0.72!286.95!ETS2;;chrX:70503529..70503549,+!p2@NONO!0.72!25.56!NONO;;chr15:66994523..66994541,+!p5@SMAD6!0.72!4.23!SMAD6;;chr11:47399920..47399931,-!p7@SPI1!0.72!4.23!SPI1;;chr2:60780753..60780800,-!p1@BCL11A!0.70!22.35!BCL11A;;chr19:12163769..12163798,-!p1@ZNF878!0.70!5.42!ZNF878;;chr2:100759010..100759035,-!p1@AFF3!0.70!4.06!AFF3;;chr6:21593973..21593988,+!p1@SOX4!0.69!160.32!SOX4;;chr16:29818160..29818188,+!p6@MAZ!0.69!20.48!MAZ;;chr6:20402102..20402152,+!p1@E2F3!0.69!18.11!E2F3;;chr5:88179195..88179224,-!p3@MEF2C!0.69!6.60!MEF2C;;chr2:60778035..60778060,-!p4@BCL11A!0.69!4.74!BCL11A;;chr17:46655672..46655697,-!p3@HOXB4!0.69!3.89!HOXB4;;chr11:32457075..32457095,-!p1@WT1!0.69!3.89!WT1;;chr16:68119324..68119364,+!p1@NFATC3!0.68!18.96!NFATC3;;chr17:46622114..46622138,-!p4@HOXB2!0.68!6.09!HOXB2;;chr8:116680833..116680881,-!p7@TRPS1!0.68!6.09!TRPS1;;chr16:88752889..88752921,-!p1@SNAI3!0.68!4.57!SNAI3;;chr17:46622229..46622257,-!p6@HOXB2!0.68!4.57!HOXB2;;chr6:21597765..21597779,+!p2@SOX4!0.67!33.86!SOX4;;chr14:55493763..55493824,-!p1@WDHD1!0.67!32.00!WDHD1;;chr2:66662249..66662267,+!p2@MEIS1!0.67!15.91!MEIS1;;chr19:20011775..20011800,+!p2@ZNF93!0.67!7.11!ZNF93;;chr7:128577972..128578047,+!p1@IRF5!0.67!6.26!IRF5;;chr17:46667594..46667619,-!p1@HOXB3!0.67!3.72!HOXB3;;chr11:32457103..32457123,-!p3@WT1!0.67!3.72!WT1;;chr14:65568389..65568408,-!p4@MAX!0.67!3.72!MAX;;chr15:66994561..66994597,+!p2@SMAD6!0.66!9.48!SMAD6;;chr8:116680215..116680245,-!p6@TRPS1!0.66!5.93!TRPS1;;chr19:20011731..20011743,+!p3@ZNF93!0.66!4.91!ZNF93;;chr2:16080635..16080650,+!p4@MYCN!0.66!3.56!MYCN;;chr19:45579725..45579743,-!p1@ZNF296!0.65!17.78!ZNF296;;chr19:19976683..19976709,+!p1@ZNF253!0.65!17.61!ZNF253;;chr19:20959098..20959117,+!p1@ZNF66P!0.65!16.25!ZNF66P;;chr21:36421535..36421610,-!p2@RUNX1!0.65!14.22!RUNX1;;chr7:149470540..149470596,-!p2@ZNF467!0.65!4.74!ZNF467;;chr7:64363638..64363667,+!p1@ZNF273!0.64!19.64!ZNF273;;chr5:124084493..124084524,-!p2@ZNF608!0.64!8.30!ZNF608;;chr2:100759037..100759058,-!p2@AFF3!0.64!3.39!AFF3;;chr15:57210961..57211012,+!p3@TCF12!0.63!12.02!TCF12;;chr17:42295777..42295816,-!p7@UBTF!0.63!4.06!UBTF;;chr11:128563948..128564003,+!p1@FLI1!0.62!45.71!FLI1;;chr16:88752836..88752852,-!p3@SNAI3!0.62!3.22!SNAI3;;chr19:13213465..13213478,-!p7@LYL1!0.62!3.22!LYL1;;chr19:13213634..13213645,-!p8@LYL1!0.62!3.22!LYL1;;chr2:66662396..66662407,+!p4@MEIS1!0.62!3.22!MEIS1;;chr6:135513595..135513617,+!p4@MYB!0.62!3.22!MYB;;chr20:35201993..35202050,+!p1@TGIF2!0.61!41.31!TGIF2;;chr14:65569101..65569119,-!p3@MAX!0.61!11.17!MAX;;chr1:247171316..247171336,-!p3@ZNF695!0.61!4.91!ZNF695;;chr1:92950138..92950159,-!p4@GFI1!0.61!3.05!GFI1;;chr11:128562372..128562397,+!p4@FLI1!0.61!3.05!FLI1;;chr12:54694738..54694749,-!p5@NFE2!0.61!3.05!NFE2;;chr17:40440446..40440464,+!p5@STAT5A!0.61!3.05!STAT5A;;chr19:23433144..23433204,-!p1@ZNF724P!0.60!15.91!ZNF724P;;chr8:72756063..72756125,-!p1@MSC!0.60!6.77!MSC;;chr18:47814010..47814021,-!p3@CXXC1!0.60!5.42!CXXC1;;chr11:47236584..47236679,+!p1@DDB2!0.59!38.77!DDB2;;chr16:67063211..67063240,+!p2@CBFB!0.59!16.42!CBFB;;chr7:64126535..64126559,+!p2@ZNF107!0.59!6.94!ZNF107;;chr19:12203069..12203094,+!p2@ZNF788!0.59!4.57!ZNF788;;chr17:40441330..40441344,+!p9@STAT5A!0.59!2.88!STAT5A;;chr12:56415246..56415286,+!p2@IKZF4!0.59!2.88!IKZF4;;chr3:18487057..18487105,-!p4@SATB1!0.59!2.88!SATB1;;chr2:8822176..8822196,+!p1@ID2!0.58!487.05!ID2;;chr19:56988677..56988729,-!p1@ZNF667!0.58!5.59!ZNF667;;chr1:221052733..221052749,+!p2@HLX!0.58!3.89!HLX;;chr1:158979686..158979745,+!p1@IFI16!0.57!112.24!IFI16;;chr19:21264991..21265026,+!p1@ZNF714!0.57!21.67!ZNF714;;chr17:41322281..41322328,-!p2@BRCA1!0.57!9.14!BRCA1;;chr2:214015111..214015179,-!p1@IKZF2!0.57!5.42!IKZF2;;chr1:158985493..158985535,+!p4@IFI16!0.57!4.57!IFI16;;chr1:3569101..3569115,+!p2@TP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| ||
| | |ffid_belonging_in_development=CL:0000049,CL:0000134 | ||
| | |||
| | |||
| | |||
|fonse_cell_line=FF:0101035 | |fonse_cell_line=FF:0101035 | ||
|fonse_cell_line_closure=FF:0101035 | |fonse_cell_line_closure=FF:0101035 | ||
Line 66: | Line 40: | ||
|fonse_treatment= | |fonse_treatment= | ||
|fonse_treatment_closure= | |fonse_treatment_closure= | ||
|has_quality= | |has_quality= | ||
|is_a=EFO:0002091;;FF: | |hg19bam=http://fantom.gsc.riken.jp/5/datafiles/latest/basic/human.cell_line.hCAGE/acute%2520myeloid%2520leukemia%2520%2528FAB%2520M4%2529%2520cell%2520line%253aHNT-34.CNhs13504.10831-111D3.hg19.nobarcode.bam | ||
|hg19ctss=http://fantom.gsc.riken.jp/5/datafiles/latest/basic/human.cell_line.hCAGE/acute%2520myeloid%2520leukemia%2520%2528FAB%2520M4%2529%2520cell%2520line%253aHNT-34.CNhs13504.10831-111D3.hg19.ctss.bed.gz | |||
|hg19fasta=http://fantom.gsc.riken.jp/5/datafiles/latest/basic/human.cell_line.hCAGE/acute%2520myeloid%2520leukemia%2520%2528FAB%2520M4%2529%2520cell%2520line%253aHNT-34.CNhs13504.10831-111D3.hg19.nobarcode.rdna.fa.gz | |||
|hg38bam=http://fantom.gsc.riken.jp/5/datafiles/reprocessed/hg38_v2/basic/human.cell_line.hCAGE/acute%2520myeloid%2520leukemia%2520%2528FAB%2520M4%2529%2520cell%2520line%253aHNT-34.CNhs13504.10831-111D3.hg38.nobarcode.bam | |||
|hg38ctss=http://fantom.gsc.riken.jp/5/datafiles/reprocessed/hg38_v2/basic/human.cell_line.hCAGE/acute%2520myeloid%2520leukemia%2520%2528FAB%2520M4%2529%2520cell%2520line%253aHNT-34.CNhs13504.10831-111D3.hg38.nobarcode.ctss.bed.gz | |||
|id=FF:10831-111D3 | |||
|is_a=EFO:0002091;;FF:0000210;;FF:0101883 | |||
|is_obsolete= | |||
|library_id=CNhs13504 | |||
|library_id_phase_based=2:CNhs13504 | |||
|microRNAs= | |||
|microRNAs_nn= | |||
|microRNAs_nonnovel_cage=http://fantom.gsc.riken.jp/5/suppl/De_Rie_et_al_2017/vis_viewer/#/human#cage;sample;10831 | |||
|microRNAs_novel_cage=http://fantom.gsc.riken.jp/5/suppl/De_Rie_et_al_2017/vis_viewer_novel/#/human#cage;sample;10831 | |||
|name=acute myeloid leukemia (FAB M4) cell line:HNT-34 | |||
|namespace=FANTOM5 | |namespace=FANTOM5 | ||
|part_of= | |part_of= | ||
|profile_cagescan=,,, | |||
|profile_hcage=CNhs13504,LSID1025,release012,COMPLETED | |||
|profile_rnaseq= | |||
|profile_srnaseq=,,, | |||
|refex=http://refex.dbcls.jp/genelist.php?lang | |||
|repeat_enrich_byfamily=0,0,0,0,0,0,0,-0.160318030086386,0,-0.150716646767817,0.330562735382307,0,0,0,0,0,0,0,0,0,0,0.0679228958305446,0.224576337417664,0,-0.0266775249227309,0,0,0,0,0.0679228958305446,0.0804075405890025,0,0,0.394684250693829,0,0,0,0,0,0,0.337174208843801,0,0,0,0,0,-0.0825769742531647,0.0679228958305446,0,0,0,0,0,0,0,0.279365102084731,0,0,0,0.0679228958305446,0,-0.0425581723543812,0,0.169347281383047,0,0,-0.0294207313825524,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,-0.115193843580584,0,0,0,-0.123516132890877,0.258348669475303,0.0633227427128485,0,0,0,-0.0301124554071618,0.17400110607178,0,0,0,0.0679228958305446,0,0,0.0679228958305446,0,0,0,0,0,0,0,0,0,0,0.015914574786371,0.0679228958305446,0,0,-0.0552799687432409,-0.255457806909247,0,0,0.149373675564245,0,0,0 | |||
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| |||
|rna_box=111 | |||
|rna_catalog_number= | |||
|rna_concentration=0.876 | |||
|rna_extraction_protocol=OP-RNA-extraction-totalRNA-miRNeasy_Mini-v1.0 | |||
|rna_lot_number= | |||
|rna_od260/230=2.03 | |||
|rna_od260/280=1.98 | |||
|rna_position=D3 | |||
|rna_rin= | |||
|rna_sample_type=total RNA | |||
|rna_tube_id=111D3 | |||
|rna_weight_ug=10.5 | |||
|sample_age=45 | |||
|sample_category=cell lines | |||
|sample_cell_catalog=RCB1296 | |||
|sample_cell_line=HNT-34 | |||
|sample_cell_lot= | |||
|sample_cell_type=myeloid progenitor cell | |||
|sample_collaboration=Yukio Nakamura (RIKEN BRC) | |||
|sample_company=RIKEN Bioresource centre | |||
|sample_description= | |||
|sample_dev_stage= | |||
|sample_disease=acute myeloid leukemia (FAB M4) | |||
|sample_donor(cell lot)= | |||
|sample_ethnicity=unknown | |||
|sample_experimental_condition= | |||
|sample_gostat=GO:0044464;cell part;0!GO:0005622;intracellular;0!GO:0044424;intracellular part;1.78241139048104e-261!GO:0043227;membrane-bound organelle;8.18868135304801e-233!GO:0043231;intracellular membrane-bound organelle;2.8095939727106e-232!GO:0043226;organelle;1.51582710492199e-220!GO:0043229;intracellular organelle;1.11938279373041e-219!GO:0044422;organelle part;2.77652291499064e-154!GO:0005737;cytoplasm;8.98545897679596e-154!GO:0044446;intracellular organelle part;1.1173761077025e-152!GO:0005634;nucleus;6.9638279098854e-125!GO:0032991;macromolecular complex;1.01104259094348e-121!GO:0044237;cellular metabolic process;8.10192434764875e-119!GO:0044238;primary metabolic process;4.77515773438054e-115!GO:0043170;macromolecule metabolic process;4.70329031818371e-111!GO:0044444;cytoplasmic part;1.74758506397429e-110!GO:0030529;ribonucleoprotein complex;1.1462169501523e-103!GO:0044428;nuclear part;2.7881120710611e-98!GO:0043233;organelle lumen;3.43019644971907e-91!GO:0031974;membrane-enclosed lumen;3.43019644971907e-91!GO:0003723;RNA binding;1.5899824769371e-90!GO:0005739;mitochondrion;8.8115519268055e-79!GO:0006139;nucleobase, nucleoside, nucleotide and nucleic acid metabolic process;4.03843958373176e-73!GO:0043283;biopolymer metabolic process;9.5373959082012e-73!GO:0010467;gene expression;3.72128078273238e-67!GO:0006396;RNA processing;8.9995535071327e-66!GO:0005515;protein binding;3.33087581346259e-64!GO:0043234;protein complex;8.41316559210089e-61!GO:0031981;nuclear lumen;2.54924653387949e-59!GO:0005840;ribosome;2.87345047582356e-58!GO:0006412;translation;4.776086093404e-58!GO:0006259;DNA metabolic process;8.34381876043864e-55!GO:0044429;mitochondrial part;1.82621122084941e-53!GO:0003735;structural constituent of ribosome;1.63324737239172e-50!GO:0016071;mRNA metabolic process;2.42366131677417e-49!GO:0019538;protein metabolic process;3.05649911458752e-49!GO:0003676;nucleic acid binding;2.6373125722644e-47!GO:0044249;cellular biosynthetic process;3.43135459954538e-47!GO:0031967;organelle envelope;1.41512048139895e-45!GO:0008380;RNA splicing;1.63357514446417e-45!GO:0031975;envelope;3.35217688231147e-45!GO:0044267;cellular protein metabolic process;1.46111574548517e-44!GO:0044260;cellular macromolecule metabolic process;4.4032709861906e-44!GO:0009058;biosynthetic process;1.48033093639683e-43!GO:0006397;mRNA processing;1.75421042792095e-43!GO:0033279;ribosomal subunit;4.14885274182666e-43!GO:0009059;macromolecule biosynthetic process;1.26063223848427e-42!GO:0016043;cellular component organization and biogenesis;1.91194143469262e-42!GO:0031090;organelle membrane;2.30344103597241e-40!GO:0022613;ribonucleoprotein complex biogenesis and assembly;4.87191181359286e-40!GO:0005829;cytosol;1.13238653177026e-38!GO:0033036;macromolecule localization;2.93849144939161e-38!GO:0006996;organelle organization and biogenesis;3.95930935126264e-38!GO:0015031;protein transport;1.23001915779383e-36!GO:0005654;nucleoplasm;1.74491073236601e-36!GO:0043228;non-membrane-bound organelle;3.71074196387296e-36!GO:0043232;intracellular non-membrane-bound organelle;3.71074196387296e-36!GO:0065003;macromolecular complex assembly;5.84809461840789e-36!GO:0007049;cell cycle;2.07540863888293e-35!GO:0045184;establishment of protein localization;5.74602234281152e-34!GO:0008104;protein localization;1.12848650048826e-33!GO:0005740;mitochondrial envelope;1.63652032975287e-33!GO:0016070;RNA metabolic process;2.47505512284708e-33!GO:0019866;organelle inner membrane;2.94650193962561e-33!GO:0005681;spliceosome;3.31359029663823e-33!GO:0000166;nucleotide binding;7.05776815082199e-33!GO:0006974;response to DNA damage stimulus;1.96160906337499e-32!GO:0046907;intracellular transport;3.57240213454537e-32!GO:0005694;chromosome;9.79299617728477e-32!GO:0022607;cellular component assembly;4.74191500744901e-31!GO:0031966;mitochondrial membrane;5.57889068711625e-31!GO:0005743;mitochondrial inner membrane;1.45017038542253e-30!GO:0005830;cytosolic ribosome (sensu Eukaryota);1.54756100406355e-30!GO:0006886;intracellular protein transport;6.9284547958947e-29!GO:0044451;nucleoplasm part;4.90018655969873e-28!GO:0044445;cytosolic part;8.33408555124397e-28!GO:0022402;cell cycle process;1.1874223513972e-27!GO:0044427;chromosomal part;1.43765048244125e-27!GO:0006281;DNA repair;1.79668682523792e-27!GO:0044455;mitochondrial membrane part;6.85467620353339e-25!GO:0005730;nucleolus;1.08356846538297e-24!GO:0006119;oxidative phosphorylation;2.60389677928526e-24!GO:0031980;mitochondrial lumen;3.23946231630595e-24!GO:0005759;mitochondrial matrix;3.23946231630595e-24!GO:0016462;pyrophosphatase activity;4.01346043609572e-24!GO:0016818;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides;4.46586261652785e-24!GO:0051276;chromosome organization and biogenesis;5.36191721843734e-24!GO:0016817;hydrolase activity, acting on acid anhydrides;6.10435774240336e-24!GO:0000278;mitotic cell cycle;7.11434474766117e-24!GO:0051649;establishment of cellular localization;2.6019659970622e-23!GO:0017111;nucleoside-triphosphatase activity;4.29768296020311e-23!GO:0032553;ribonucleotide binding;8.37627557407523e-23!GO:0032555;purine ribonucleotide binding;8.37627557407523e-23!GO:0051641;cellular localization;9.19234840294888e-23!GO:0009719;response to endogenous stimulus;1.72487753157685e-22!GO:0017076;purine nucleotide binding;2.88476403139187e-22!GO:0015935;small ribosomal subunit;2.91625273506319e-22!GO:0006260;DNA replication;5.26786441494702e-22!GO:0015934;large ribosomal subunit;5.26786441494702e-22!GO:0005524;ATP binding;1.87297187522263e-21!GO:0032559;adenyl ribonucleotide binding;4.93738561852849e-21!GO:0022618;protein-RNA complex assembly;6.78911672425764e-21!GO:0030554;adenyl nucleotide binding;3.07252153800816e-20!GO:0006457;protein folding;3.66950466557183e-20!GO:0042254;ribosome biogenesis and assembly;9.1142647523452e-20!GO:0022403;cell cycle phase;1.02156089378575e-19!GO:0006325;establishment and/or maintenance of chromatin architecture;4.74501231053161e-19!GO:0006512;ubiquitin cycle;5.42613208321361e-19!GO:0005746;mitochondrial respiratory chain;1.1133073047438e-18!GO:0016874;ligase activity;1.8884905189068e-18!GO:0006323;DNA packaging;2.27056311603433e-18!GO:0016887;ATPase activity;2.32004327037612e-18!GO:0044265;cellular macromolecule catabolic process;4.39326394919552e-18!GO:0000087;M phase of mitotic cell cycle;8.75637051616343e-18!GO:0042623;ATPase activity, coupled;1.08877414890954e-17!GO:0007067;mitosis;2.63552075476715e-17!GO:0008135;translation factor activity, nucleic acid binding;3.70480814477408e-17!GO:0016604;nuclear body;4.48944662307296e-17!GO:0051301;cell division;6.56130471243813e-17!GO:0000502;proteasome complex (sensu Eukaryota);7.04070744308434e-17!GO:0016655;oxidoreductase activity, acting on NADH or NADPH, quinone or similar compound as acceptor;8.27400754211963e-17!GO:0000398;nuclear mRNA splicing, via spliceosome;8.85192713585954e-17!GO:0000375;RNA splicing, via transesterification reactions;8.85192713585954e-17!GO:0000377;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile;8.85192713585954e-17!GO:0005761;mitochondrial ribosome;1.2731303596025e-16!GO:0000313;organellar ribosome;1.2731303596025e-16!GO:0050136;NADH dehydrogenase (quinone) activity;2.18638013238721e-16!GO:0003954;NADH dehydrogenase activity;2.18638013238721e-16!GO:0008137;NADH dehydrogenase (ubiquinone) activity;2.18638013238721e-16!GO:0051603;proteolysis involved in cellular protein catabolic process;2.79774221917682e-16!GO:0019941;modification-dependent protein catabolic process;2.97081896856081e-16!GO:0043632;modification-dependent macromolecule catabolic process;2.97081896856081e-16!GO:0006511;ubiquitin-dependent protein catabolic process;3.58289767093799e-16!GO:0043285;biopolymer catabolic process;4.27949949388424e-16!GO:0044257;cellular protein catabolic process;7.82588627495011e-16!GO:0008134;transcription factor binding;9.30057492642399e-16!GO:0000279;M phase;1.35753418358245e-15!GO:0005843;cytosolic small ribosomal subunit (sensu Eukaryota);1.5961174987465e-15!GO:0000785;chromatin;2.18278761819141e-15!GO:0005842;cytosolic large ribosomal subunit (sensu Eukaryota);2.95728899500766e-15!GO:0051186;cofactor metabolic process;3.29174158764825e-15!GO:0044248;cellular catabolic process;4.04333143216524e-15!GO:0009057;macromolecule catabolic process;4.99481306648782e-15!GO:0043412;biopolymer modification;5.67099851392354e-15!GO:0042775;organelle ATP synthesis coupled electron transport;5.92006916548625e-15!GO:0042773;ATP synthesis coupled electron transport;5.92006916548625e-15!GO:0006605;protein targeting;6.25185350529278e-15!GO:0004386;helicase activity;6.47955318796215e-15!GO:0044453;nuclear membrane part;7.20797006830451e-15!GO:0051726;regulation of cell cycle;9.27008015878613e-15!GO:0000074;regulation of progression through cell cycle;1.43581468552251e-14!GO:0030964;NADH dehydrogenase complex (quinone);1.60079089507212e-14!GO:0045271;respiratory chain complex I;1.60079089507212e-14!GO:0005747;mitochondrial respiratory chain complex I;1.60079089507212e-14!GO:0003743;translation initiation factor activity;4.74471031993834e-14!GO:0006120;mitochondrial electron transport, NADH to ubiquinone;5.32328612718815e-14!GO:0031965;nuclear membrane;5.82827559478861e-14!GO:0050657;nucleic acid transport;1.18827491581953e-13!GO:0051236;establishment of RNA localization;1.18827491581953e-13!GO:0050658;RNA transport;1.18827491581953e-13!GO:0006364;rRNA processing;1.74501533694216e-13!GO:0016607;nuclear speck;1.84425712026537e-13!GO:0006403;RNA localization;1.85901157116428e-13!GO:0048770;pigment granule;2.33328315800261e-13!GO:0042470;melanosome;2.33328315800261e-13!GO:0016072;rRNA metabolic process;3.02907573649622e-13!GO:0006913;nucleocytoplasmic transport;3.94569061061229e-13!GO:0012501;programmed cell death;4.48816616087023e-13!GO:0051082;unfolded protein binding;4.48816616087023e-13!GO:0006333;chromatin assembly or disassembly;4.48816616087023e-13!GO:0006915;apoptosis;4.4909032489186e-13!GO:0006413;translational initiation;4.50438317567729e-13!GO:0016568;chromatin modification;5.58261709384157e-13!GO:0005635;nuclear envelope;7.09996435093078e-13!GO:0016651;oxidoreductase activity, acting on NADH or NADPH;8.58645305430169e-13!GO:0012505;endomembrane system;9.2071619205629e-13!GO:0051169;nuclear transport;1.00658269775262e-12!GO:0005643;nuclear pore;1.63313565251579e-12!GO:0030163;protein catabolic process;1.70757450136603e-12!GO:0008026;ATP-dependent helicase activity;2.01956668102233e-12!GO:0006464;protein modification process;2.29705724758338e-12!GO:0065004;protein-DNA complex assembly;3.63140916591291e-12!GO:0006261;DNA-dependent DNA replication;4.72322310911853e-12!GO:0006732;coenzyme metabolic process;6.55217694885799e-12!GO:0006399;tRNA metabolic process;6.78635366324097e-12!GO:0050794;regulation of cellular process;8.85306480378793e-12!GO:0043687;post-translational protein modification;9.9966409540673e-12!GO:0015931;nucleobase, nucleoside, nucleotide and nucleic acid transport;1.06783302838175e-11!GO:0009259;ribonucleotide metabolic process;1.14722953822625e-11!GO:0003697;single-stranded DNA binding;1.27088361491412e-11!GO:0051028;mRNA transport;1.3315583264886e-11!GO:0065002;intracellular protein transport across a membrane;1.57984536635219e-11!GO:0043566;structure-specific DNA binding;1.64417508854713e-11!GO:0006163;purine nucleotide metabolic process;1.79965499050534e-11!GO:0008219;cell death;1.90565566854989e-11!GO:0016265;death;1.90565566854989e-11!GO:0006446;regulation of translational initiation;2.41657063321126e-11!GO:0008565;protein transporter activity;3.01243747699366e-11!GO:0006164;purine nucleotide biosynthetic process;3.09574150337564e-11!GO:0006366;transcription from RNA polymerase II promoter;4.06729983554905e-11!GO:0009260;ribonucleotide biosynthetic process;4.339831886752e-11!GO:0046930;pore complex;7.2410502702176e-11!GO:0030532;small nuclear ribonucleoprotein complex;1.48841228517752e-10!GO:0009150;purine ribonucleotide metabolic process;2.70303610392149e-10!GO:0055086;nucleobase, nucleoside and nucleotide metabolic process;3.38584858092415e-10!GO:0000775;chromosome, pericentric region;4.38866565035765e-10!GO:0009152;purine ribonucleotide biosynthetic process;4.843453890837e-10!GO:0016779;nucleotidyltransferase activity;6.03601836354814e-10!GO:0017038;protein import;6.14447227139126e-10!GO:0019222;regulation of metabolic process;6.14447227139126e-10!GO:0048193;Golgi vesicle transport;6.38250046034717e-10!GO:0046961;hydrogen ion transporting ATPase activity, rotational mechanism;6.45673049547577e-10!GO:0003712;transcription cofactor activity;1.21473304912959e-09!GO:0009060;aerobic respiration;1.7721088974527e-09!GO:0046933;hydrogen ion transporting ATP synthase activity, rotational mechanism;1.85555228029981e-09!GO:0044432;endoplasmic reticulum part;1.97210140338334e-09!GO:0016591;DNA-directed RNA polymerase II, holoenzyme;1.98180623929287e-09!GO:0019829;cation-transporting ATPase activity;3.11854749143207e-09!GO:0006334;nucleosome assembly;4.50721090321234e-09!GO:0016192;vesicle-mediated transport;4.82250015060706e-09!GO:0007005;mitochondrion organization and biogenesis;6.02232238380587e-09!GO:0031497;chromatin assembly;6.26033074666093e-09!GO:0051188;cofactor biosynthetic process;8.94379285246367e-09!GO:0006793;phosphorus metabolic process;9.01514793382899e-09!GO:0006796;phosphate metabolic process;9.01514793382899e-09!GO:0006461;protein complex assembly;9.78158809852632e-09!GO:0015986;ATP synthesis coupled proton transport;1.03978012867951e-08!GO:0015985;energy coupled proton transport, down electrochemical gradient;1.03978012867951e-08!GO:0016876;ligase activity, forming aminoacyl-tRNA and related compounds;1.15961475778532e-08!GO:0004812;aminoacyl-tRNA ligase activity;1.15961475778532e-08!GO:0016875;ligase activity, forming carbon-oxygen bonds;1.15961475778532e-08!GO:0045333;cellular respiration;1.67696286190225e-08!GO:0009142;nucleoside triphosphate biosynthetic process;1.89944373225041e-08!GO:0009201;ribonucleoside triphosphate biosynthetic process;1.89944373225041e-08!GO:0015078;hydrogen ion transmembrane transporter activity;1.9009604720294e-08!GO:0016310;phosphorylation;2.1499098969795e-08!GO:0043038;amino acid activation;2.20713706985815e-08!GO:0006418;tRNA aminoacylation for protein translation;2.20713706985815e-08!GO:0043039;tRNA aminoacylation;2.20713706985815e-08!GO:0009117;nucleotide metabolic process;2.28981291725694e-08!GO:0031323;regulation of cellular metabolic process;2.48627704726819e-08!GO:0009199;ribonucleoside triphosphate metabolic process;2.5343520733753e-08!GO:0009141;nucleoside triphosphate metabolic process;2.551038726872e-08!GO:0003899;DNA-directed RNA polymerase activity;2.75429302697318e-08!GO:0009055;electron carrier activity;2.77810475558046e-08!GO:0005657;replication fork;3.51594365634278e-08!GO:0016787;hydrolase activity;3.73508532818713e-08!GO:0009206;purine ribonucleoside triphosphate biosynthetic process;3.87381503893317e-08!GO:0009145;purine nucleoside triphosphate biosynthetic process;3.87381503893317e-08!GO:0009056;catabolic process;4.09521013948558e-08!GO:0051325;interphase;4.15441479891167e-08!GO:0050789;regulation of biological process;5.01886033256007e-08!GO:0009205;purine ribonucleoside triphosphate metabolic process;5.01886033256007e-08!GO:0009144;purine nucleoside triphosphate metabolic process;5.01886033256007e-08!GO:0008639;small protein conjugating enzyme activity;5.96819925858369e-08!GO:0051329;interphase of mitotic cell cycle;6.50000500208997e-08!GO:0000075;cell cycle checkpoint;6.96320920431546e-08!GO:0006099;tricarboxylic acid cycle;7.10713774772098e-08!GO:0046356;acetyl-CoA catabolic process;7.10713774772098e-08!GO:0006084;acetyl-CoA metabolic process;8.70518936887074e-08!GO:0006754;ATP biosynthetic process;8.86667034966177e-08!GO:0006753;nucleoside phosphate metabolic process;8.86667034966177e-08!GO:0000245;spliceosome assembly;9.02929849711569e-08!GO:0016879;ligase activity, forming carbon-nitrogen bonds;1.10932246953147e-07!GO:0016469;proton-transporting two-sector ATPase complex;1.12152890280351e-07!GO:0004842;ubiquitin-protein ligase activity;1.13469600780892e-07!GO:0008094;DNA-dependent ATPase activity;1.31881218598416e-07!GO:0005819;spindle;1.42809182376214e-07!GO:0016740;transferase activity;1.43251788511102e-07!GO:0005783;endoplasmic reticulum;1.47671285999036e-07!GO:0042981;regulation of apoptosis;1.60942183798234e-07!GO:0046034;ATP metabolic process;1.69899498761985e-07!GO:0019787;small conjugating protein ligase activity;2.14637068533864e-07!GO:0043067;regulation of programmed cell death;2.25955758229231e-07!GO:0005839;proteasome core complex (sensu Eukaryota);2.83120009170495e-07!GO:0006350;transcription;3.96975289745262e-07!GO:0045259;proton-transporting ATP synthase complex;4.01447020057165e-07!GO:0006752;group transfer coenzyme metabolic process;4.01465182930665e-07!GO:0042175;nuclear envelope-endoplasmic reticulum network;5.12912368622857e-07!GO:0051187;cofactor catabolic process;5.12912368622857e-07!GO:0045786;negative regulation of progression through cell cycle;5.33531482154378e-07!GO:0006606;protein import into nucleus;6.07332846477773e-07!GO:0031202;RNA splicing factor activity, transesterification mechanism;6.46978372836719e-07!GO:0051170;nuclear import;6.55299041180953e-07!GO:0051246;regulation of protein metabolic process;7.00087611379128e-07!GO:0009109;coenzyme catabolic process;8.11545723169225e-07!GO:0003724;RNA helicase activity;8.37655229230974e-07!GO:0006310;DNA recombination;9.43679884018373e-07!GO:0005789;endoplasmic reticulum membrane;1.03049887052411e-06!GO:0005815;microtubule organizing center;1.13126742496906e-06!GO:0005813;centrosome;1.13740125419472e-06!GO:0009108;coenzyme biosynthetic process;1.22854011486859e-06!GO:0007051;spindle organization and biogenesis;1.38208660608818e-06!GO:0003713;transcription coactivator activity;1.41523787544187e-06!GO:0015077;monovalent inorganic cation transmembrane transporter activity;1.42186158856691e-06!GO:0010468;regulation of gene expression;1.54187829999154e-06!GO:0032446;protein modification by small protein conjugation;1.59256282815704e-06!GO:0019899;enzyme binding;1.5948406606927e-06!GO:0004298;threonine endopeptidase activity;1.61440622240367e-06!GO:0048523;negative regulation of cellular process;1.62927511042571e-06!GO:0009165;nucleotide biosynthetic process;1.79163346688099e-06!GO:0003690;double-stranded DNA binding;2.02264288109516e-06!GO:0006302;double-strand break repair;2.06036913567993e-06!GO:0016741;transferase activity, transferring one-carbon groups;3.22985009297407e-06!GO:0016567;protein ubiquitination;3.84395508079649e-06!GO:0005793;ER-Golgi intermediate compartment;3.91810620455483e-06!GO:0008168;methyltransferase activity;3.95826354371923e-06!GO:0016881;acid-amino acid ligase activity;4.62499431923164e-06!GO:0005794;Golgi apparatus;4.71414756112401e-06!GO:0007249;I-kappaB kinase/NF-kappaB cascade;5.03565724719104e-06!GO:0048475;coated membrane;5.40971164846962e-06!GO:0030117;membrane coat;5.40971164846962e-06!GO:0015630;microtubule cytoskeleton;5.40971164846962e-06!GO:0005762;mitochondrial large ribosomal subunit;5.7264667243374e-06!GO:0000315;organellar large ribosomal subunit;5.7264667243374e-06!GO:0051168;nuclear export;6.40057947109486e-06!GO:0043623;cellular protein complex assembly;6.53463870773951e-06!GO:0016564;transcription repressor activity;6.81895546692258e-06!GO:0043122;regulation of I-kappaB kinase/NF-kappaB cascade;6.92776571283619e-06!GO:0006888;ER to Golgi vesicle-mediated transport;7.06193707436378e-06!GO:0044452;nucleolar part;7.30185512083799e-06!GO:0043123;positive regulation of I-kappaB kinase/NF-kappaB cascade;7.39186524109736e-06!GO:0016772;transferase activity, transferring phosphorus-containing groups;7.61789073163661e-06!GO:0005667;transcription factor complex;7.75319071587425e-06!GO:0000776;kinetochore;7.8558067801987e-06!GO:0000786;nucleosome;8.84101993489592e-06!GO:0031324;negative regulation of cellular metabolic process;9.13400909440076e-06!GO:0019219;regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process;9.1615915637596e-06!GO:0005852;eukaryotic translation initiation factor 3 complex;9.33781516485595e-06!GO:0016563;transcription activator activity;9.70261883660745e-06!GO:0065009;regulation of a molecular function;1.00333504601406e-05!GO:0016363;nuclear matrix;1.11517113692915e-05!GO:0006613;cotranslational protein targeting to membrane;1.13216352484637e-05!GO:0042625;ATPase activity, coupled to transmembrane movement of ions;1.37766712080556e-05!GO:0030120;vesicle coat;1.41967213045366e-05!GO:0030662;coated vesicle membrane;1.41967213045366e-05!GO:0000314;organellar small ribosomal subunit;1.43162017328303e-05!GO:0005763;mitochondrial small ribosomal subunit;1.43162017328303e-05!GO:0003677;DNA binding;1.58067247095849e-05!GO:0047485;protein N-terminus binding;1.7531782624735e-05!GO:0007059;chromosome segregation;1.91540591796585e-05!GO:0030530;heterogeneous nuclear ribonucleoprotein complex;2.18695307601605e-05!GO:0015405;P-P-bond-hydrolysis-driven transmembrane transporter activity;2.2170108641701e-05!GO:0015399;primary active transmembrane transporter activity;2.2170108641701e-05!GO:0006414;translational elongation;2.2721375930295e-05!GO:0003678;DNA helicase activity;2.49937101004287e-05!GO:0045934;negative regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process;2.9182496863645e-05!GO:0003755;peptidyl-prolyl cis-trans isomerase activity;3.282134860007e-05!GO:0030880;RNA polymerase complex;3.44272974994926e-05!GO:0065007;biological regulation;3.52239554971519e-05!GO:0006839;mitochondrial transport;3.57430757199887e-05!GO:0048519;negative regulation of biological process;3.58699243038905e-05!GO:0003684;damaged DNA binding;3.68961446750502e-05!GO:0016491;oxidoreductase activity;3.98502350455776e-05!GO:0046483;heterocycle metabolic process;4.11877509494485e-05!GO:0051427;hormone receptor binding;4.16294946795469e-05!GO:0016859;cis-trans isomerase activity;4.34301568161912e-05!GO:0000151;ubiquitin ligase complex;4.56586030093877e-05!GO:0000228;nuclear chromosome;4.77537389452128e-05!GO:0006357;regulation of transcription from RNA polymerase II promoter;4.83527901926818e-05!GO:0003729;mRNA binding;4.97347544340619e-05!GO:0006091;generation of precursor metabolites and energy;5.16935167045181e-05!GO:0007243;protein kinase cascade;5.27372599657044e-05!GO:0008186;RNA-dependent ATPase activity;5.60888832524569e-05!GO:0003682;chromatin binding;5.86938028823061e-05!GO:0016853;isomerase activity;5.93097076397501e-05!GO:0005768;endosome;6.67370579400648e-05!GO:0032774;RNA biosynthetic process;7.04640821708667e-05!GO:0006352;transcription initiation;7.09622432892671e-05!GO:0043021;ribonucleoprotein binding;7.59841401591702e-05!GO:0043681;protein import into mitochondrion;7.70180329303319e-05!GO:0008033;tRNA processing;8.53546682612206e-05!GO:0006383;transcription from RNA polymerase III promoter;8.80859238809941e-05!GO:0055029;nuclear DNA-directed RNA polymerase complex;8.90677151632559e-05!GO:0000428;DNA-directed RNA polymerase complex;8.90677151632559e-05!GO:0051052;regulation of DNA metabolic process;8.90677151632559e-05!GO:0035257;nuclear hormone receptor binding;9.00352973595453e-05!GO:0006405;RNA export from nucleus;9.03786437575675e-05!GO:0045454;cell redox homeostasis;9.32564086208793e-05!GO:0006351;transcription, DNA-dependent;9.58293713344992e-05!GO:0000079;regulation of cyclin-dependent protein kinase activity;9.81945422496792e-05!GO:0006401;RNA catabolic process;0.000110965816767752!GO:0006402;mRNA catabolic process;0.000113626108646149!GO:0008654;phospholipid biosynthetic process;0.000118657074287267!GO:0032508;DNA duplex unwinding;0.000125760268156219!GO:0032392;DNA geometric change;0.000125760268156219!GO:0042770;DNA damage response, signal transduction;0.000133461396335454!GO:0005753;mitochondrial proton-transporting ATP synthase complex;0.000137247483902032!GO:0006626;protein targeting to mitochondrion;0.000143704788810269!GO:0008632;apoptotic program;0.000162106637522518!GO:0009892;negative regulation of metabolic process;0.000162616178292156!GO:0004004;ATP-dependent RNA helicase activity;0.000173870994601245!GO:0005885;Arp2/3 protein complex;0.000177073264568704!GO:0006818;hydrogen transport;0.000187554179193975!GO:0004527;exonuclease activity;0.000193977100647429!GO:0015992;proton transport;0.000193977100647429!GO:0000082;G1/S transition of mitotic cell cycle;0.000200727019613101!GO:0005770;late endosome;0.000205428709815637!GO:0006270;DNA replication initiation;0.00020771156411984!GO:0004518;nuclease activity;0.000215936026685007!GO:0015980;energy derivation by oxidation of organic compounds;0.000218122457814443!GO:0007006;mitochondrial membrane organization and biogenesis;0.000230226690059177!GO:0033178;proton-transporting two-sector ATPase complex, catalytic domain;0.000254905487210305!GO:0051087;chaperone binding;0.000261646211842846!GO:0006268;DNA unwinding during replication;0.000262952845516229!GO:0045449;regulation of transcription;0.000286465686308999!GO:0003924;GTPase activity;0.000297227739141221!GO:0019752;carboxylic acid metabolic process;0.000309161759381629!GO:0009112;nucleobase metabolic process;0.000310830191103609!GO:0006082;organic acid metabolic process;0.000318337439465766!GO:0043596;nuclear replication fork;0.000321901323905012!GO:0005525;GTP binding;0.000326859878941432!GO:0016481;negative regulation of transcription;0.000351383407882542!GO:0043069;negative regulation of programmed cell death;0.000352592282140174!GO:0005788;endoplasmic reticulum lumen;0.000360216456445952!GO:0006950;response to stress;0.000395216373837376!GO:0043066;negative regulation of apoptosis;0.00043762536093287!GO:0043492;ATPase activity, coupled to movement of substances;0.00044659389945769!GO:0000922;spindle pole;0.000456570343398422!GO:0005684;U2-dependent spliceosome;0.000461362433465225!GO:0006612;protein targeting to membrane;0.000484225993169933!GO:0045261;proton-transporting ATP synthase complex, catalytic core F(1);0.000494789965530492!GO:0000792;heterochromatin;0.000524283194767279!GO:0007093;mitotic cell cycle checkpoint;0.00053609380486555!GO:0007088;regulation of mitosis;0.000557868072895766!GO:0042626;ATPase activity, coupled to transmembrane movement of substances;0.000612029161692017!GO:0022890;inorganic cation transmembrane transporter activity;0.00064574891738688!GO:0016281;eukaryotic translation initiation factor 4F complex;0.000669015656347232!GO:0005798;Golgi-associated vesicle;0.00071037485214485!GO:0003714;transcription corepressor activity;0.000743729795608689!GO:0016251;general RNA polymerase II transcription factor activity;0.000761820398033635!GO:0006916;anti-apoptosis;0.000766828454925702!GO:0016679;oxidoreductase activity, acting on diphenols and related substances as donors;0.000768114866136819!GO:0016681;oxidoreductase activity, acting on diphenols and related substances as donors, cytochrome as acceptor;0.000768114866136819!GO:0008121;ubiquinol-cytochrome-c reductase activity;0.000768114866136819!GO:0016820;hydrolase activity, acting on acid anhydrides, catalyzing transmembrane movement of substances;0.000782749901158303!GO:0006520;amino acid metabolic process;0.000888672646465377!GO:0005637;nuclear inner membrane;0.000917648161829141!GO:0050790;regulation of catalytic activity;0.000948195127385455!GO:0008629;induction of apoptosis by intracellular signals;0.000972713774960517!GO:0000059;protein import into nucleus, docking;0.00100106900509485!GO:0031982;vesicle;0.00111209892566213!GO:0045263;proton-transporting ATP synthase complex, coupling factor F(o);0.00114169272282003!GO:0033177;proton-transporting two-sector ATPase complex, proton-transporting domain;0.00114169272282003!GO:0005769;early endosome;0.00114723291009918!GO:0030384;phosphoinositide metabolic process;0.00118888146904176!GO:0051252;regulation of RNA metabolic process;0.0011946178926195!GO:0005665;DNA-directed RNA polymerase II, core complex;0.00122291477379223!GO:0042802;identical protein binding;0.00138468475382647!GO:0007052;mitotic spindle organization and biogenesis;0.00138719132273089!GO:0004674;protein serine/threonine kinase activity;0.00140372410514344!GO:0043065;positive regulation of apoptosis;0.00146400523010619!GO:0008757;S-adenosylmethionine-dependent methyltransferase activity;0.0014810521693669!GO:0000184;mRNA catabolic process, nonsense-mediated decay;0.0014811137189602!GO:0005048;signal sequence binding;0.00150307057144154!GO:0043414;biopolymer methylation;0.00158631139332349!GO:0019843;rRNA binding;0.00160857772689437!GO:0000049;tRNA binding;0.00162704319246689!GO:0031570;DNA integrity checkpoint;0.00167107519563808!GO:0035258;steroid hormone receptor binding;0.00170183125433656!GO:0048500;signal recognition particle;0.00170467579597115!GO:0031252;leading edge;0.00175289595710767!GO:0044454;nuclear chromosome part;0.00176650289674945!GO:0009124;nucleoside monophosphate biosynthetic process;0.00182484918805015!GO:0009123;nucleoside monophosphate metabolic process;0.00182484918805015!GO:0043068;positive regulation of programmed cell death;0.0018723032268981!GO:0005838;proteasome regulatory particle (sensu Eukaryota);0.00193925999448745!GO:0008312;7S RNA binding;0.00193925999448745!GO:0051539;4 iron, 4 sulfur cluster binding;0.00195357368386196!GO:0005773;vacuole;0.00199997504935663!GO:0043601;nuclear replisome;0.00208961847622012!GO:0030894;replisome;0.00208961847622012!GO:0050662;coenzyme binding;0.00211234319355179!GO:0000226;microtubule cytoskeleton organization and biogenesis;0.00211234319355179!GO:0044440;endosomal part;0.00211234319355179!GO:0010008;endosome membrane;0.00211234319355179!GO:0006417;regulation of translation;0.00211869204076633!GO:0006275;regulation of DNA replication;0.00215662997309599!GO:0006284;base-excision repair;0.00215662997309599!GO:0000178;exosome (RNase complex);0.00223295492410557!GO:0000287;magnesium ion binding;0.00234628697974308!GO:0005758;mitochondrial intermembrane space;0.00234628697974308!GO:0006144;purine base metabolic process;0.00236586955159788!GO:0032561;guanyl ribonucleotide binding;0.00239223700235591!GO:0019001;guanyl nucleotide binding;0.00239223700235591!GO:0006289;nucleotide-excision repair;0.00250595672525986!GO:0032259;methylation;0.00266609677492501!GO:0005876;spindle microtubule;0.00268860931918787!GO:0009116;nucleoside metabolic process;0.00280783748860916!GO:0003711;transcription elongation regulator activity;0.0028097248300107!GO:0031124;mRNA 3'-end processing;0.00300746427147357!GO:0032200;telomere organization and biogenesis;0.0030406028045538!GO:0000723;telomere maintenance;0.0030406028045538!GO:0009451;RNA modification;0.00310508922236635!GO:0015036;disulfide oxidoreductase activity;0.00318028757169715!GO:0007050;cell cycle arrest;0.00336181875498439!GO:0031410;cytoplasmic vesicle;0.00342663127453823!GO:0051540;metal cluster binding;0.00355627066922813!GO:0051536;iron-sulfur cluster binding;0.00355627066922813!GO:0040029;regulation of gene expression, epigenetic;0.00362460162425572!GO:0005786;signal recognition particle, endoplasmic reticulum targeting;0.00363922928856629!GO:0048522;positive regulation of cellular process;0.00367448558470069!GO:0031072;heat shock protein binding;0.0037209849163278!GO:0006355;regulation of transcription, DNA-dependent;0.00377161245349674!GO:0046474;glycerophospholipid biosynthetic process;0.00377372950687305!GO:0007242;intracellular signaling cascade;0.00377419413869445!GO:0044431;Golgi apparatus part;0.00378443636000735!GO:0004003;ATP-dependent DNA helicase activity;0.00380317862512079!GO:0000307;cyclin-dependent protein kinase holoenzyme complex;0.00383067835295342!GO:0008408;3'-5' exonuclease activity;0.00389271250764884!GO:0043433;negative regulation of transcription factor activity;0.00390546774180393!GO:0043284;biopolymer biosynthetic process;0.00429464748161518!GO:0006614;SRP-dependent cotranslational protein targeting to membrane;0.00434397169109208!GO:0045047;protein targeting to ER;0.00434397169109208!GO:0000725;recombinational repair;0.00443202261793479!GO:0000724;double-strand break repair via homologous recombination;0.00443202261793479!GO:0016272;prefoldin complex;0.00443552028368894!GO:0031988;membrane-bound vesicle;0.00446898566541446!GO:0003746;translation elongation factor activity;0.00457967020036304!GO:0009161;ribonucleoside monophosphate metabolic process;0.00459929504653197!GO:0009156;ribonucleoside monophosphate biosynthetic process;0.00459929504653197!GO:0016765;transferase activity, transferring alkyl or aryl (other than methyl) groups;0.00460062563763936!GO:0008047;enzyme activator activity;0.00468010445992153!GO:0046489;phosphoinositide biosynthetic process;0.00472206865391501!GO:0000323;lytic vacuole;0.00474555757029038!GO:0005764;lysosome;0.00474555757029038!GO:0043488;regulation of mRNA stability;0.00476499393355457!GO:0043487;regulation of RNA stability;0.00476499393355457!GO:0016407;acetyltransferase activity;0.00482058825824405!GO:0006917;induction of apoptosis;0.00482058825824405!GO:0046128;purine ribonucleoside metabolic process;0.00487998084772394!GO:0042278;purine nucleoside metabolic process;0.00487998084772394!GO:0006650;glycerophospholipid metabolic process;0.00489380372496555!GO:0030521;androgen receptor signaling pathway;0.00492162955755608!GO:0006778;porphyrin metabolic process;0.00501823219845773!GO:0033013;tetrapyrrole metabolic process;0.00501823219845773!GO:0006338;chromatin remodeling;0.00518157562938574!GO:0016796;exonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters;0.00522825368977744!GO:0030118;clathrin coat;0.0054136530912445!GO:0006595;polyamine metabolic process;0.00560449827019159!GO:0030658;transport vesicle membrane;0.00589129826140394!GO:0000339;RNA cap binding;0.00609635268326841!GO:0000077;DNA damage checkpoint;0.00625583865177661!GO:0005853;eukaryotic translation elongation factor 1 complex;0.00626575397999246!GO:0012502;induction of programmed cell death;0.00630224474532213!GO:0031968;organelle outer membrane;0.00666006004864908!GO:0006378;mRNA polyadenylation;0.00688532512739515!GO:0042393;histone binding;0.00688532512739515!GO:0006519;amino acid and derivative metabolic process;0.00689437753417834!GO:0051098;regulation of binding;0.00698360241439593!GO:0030330;DNA damage response, signal transduction by p53 class mediator;0.00698370872103818!GO:0051287;NAD binding;0.00704631834286773!GO:0019867;outer membrane;0.00704631834286773!GO:0000070;mitotic sister chromatid segregation;0.00723358927657656!GO:0046112;nucleobase biosynthetic process;0.00723358927657656!GO:0004532;exoribonuclease activity;0.00723358927657656!GO:0016896;exoribonuclease activity, producing 5'-phosphomonoesters;0.00723358927657656!GO:0005774;vacuolar membrane;0.00724051146675395!GO:0009081;branched chain family amino acid metabolic process;0.00731209635563126!GO:0015631;tubulin binding;0.0073463875132855!GO:0006406;mRNA export from nucleus;0.00751648513576808!GO:0051101;regulation of DNA binding;0.00754995704909681!GO:0016584;nucleosome positioning;0.00758973005791079!GO:0006730;one-carbon compound metabolic process;0.00767295973308915!GO:0031123;RNA 3'-end processing;0.00799901355817353!GO:0008234;cysteine-type peptidase activity;0.00818163217290801!GO:0000726;non-recombinational repair;0.00819776104912056!GO:0000819;sister chromatid segregation;0.00821173278579916!GO:0005832;chaperonin-containing T-complex;0.00843880874859402!GO:0051789;response to protein stimulus;0.00897446443138569!GO:0006986;response to unfolded protein;0.00897446443138569!GO:0000096;sulfur amino acid metabolic process;0.00901339332166834!GO:0008139;nuclear localization sequence binding;0.00904413947534358!GO:0006376;mRNA splice site selection;0.0090918574226328!GO:0000389;nuclear mRNA 3'-splice site recognition;0.0090918574226328!GO:0005744;mitochondrial inner membrane presequence translocase complex;0.00932219244778951!GO:0031326;regulation of cellular biosynthetic process;0.00932219244778951!GO:0009119;ribonucleoside metabolic process;0.00943400187706051!GO:0000118;histone deacetylase complex;0.00944991436404787!GO:0008180;signalosome;0.0094761943653111!GO:0006891;intra-Golgi vesicle-mediated transport;0.00976138987753333!GO:0030867;rough endoplasmic reticulum membrane;0.00984266036093575!GO:0016023;cytoplasmic membrane-bound vesicle;0.00984798069086342!GO:0030663;COPI coated vesicle membrane;0.00990131521601197!GO:0030126;COPI vesicle coat;0.00990131521601197!GO:0031970;organelle envelope lumen;0.00990131521601197!GO:0009303;rRNA transcription;0.010303777517512!GO:0006607;NLS-bearing substrate import into nucleus;0.010303777517512!GO:0006779;porphyrin biosynthetic process;0.0103353857437396!GO:0033014;tetrapyrrole biosynthetic process;0.0103353857437396!GO:0006367;transcription initiation from RNA polymerase II promoter;0.0104714111916679!GO:0045892;negative regulation of transcription, DNA-dependent;0.0107922619744591!GO:0006740;NADPH regeneration;0.0110468731207935!GO:0006098;pentose-phosphate shunt;0.0110468731207935!GO:0008276;protein methyltransferase activity;0.0110739525522476!GO:0043161;proteasomal ubiquitin-dependent protein catabolic process;0.0113449075472418!GO:0044450;microtubule organizing center part;0.0114483593057921!GO:0005663;DNA replication factor C complex;0.011718545073769!GO:0007017;microtubule-based process;0.0120435160094718!GO:0016676;oxidoreductase activity, acting on heme group of donors, oxygen as acceptor;0.0122450089649111!GO:0015002;heme-copper terminal oxidase activity;0.0122450089649111!GO:0016675;oxidoreductase activity, acting on heme group of donors;0.0122450089649111!GO:0004129;cytochrome-c oxidase activity;0.0122450089649111!GO:0000790;nuclear chromatin;0.0123574959984848!GO:0004177;aminopeptidase activity;0.0126237239373335!GO:0005741;mitochondrial outer membrane;0.0129126694456131!GO:0042168;heme metabolic process;0.0129126694456131!GO:0030660;Golgi-associated vesicle membrane;0.0129126694456131!GO:0006360;transcription from RNA polymerase I promoter;0.0129775782100679!GO:0051053;negative regulation of DNA metabolic process;0.0131093852346995!GO:0030119;AP-type membrane coat adaptor complex;0.0133135927033297!GO:0000781;chromosome, telomeric region;0.0133996592094981!GO:0008630;DNA damage response, signal transduction resulting in induction of apoptosis;0.013403904550322!GO:0046822;regulation of nucleocytoplasmic transport;0.0137436769798928!GO:0003887;DNA-directed DNA polymerase activity;0.0138482471975533!GO:0007007;inner mitochondrial membrane organization and biogenesis;0.0139625504421585!GO:0044437;vacuolar part;0.0145227707023748!GO:0045045;secretory pathway;0.0145955797849701!GO:0008637;apoptotic mitochondrial changes;0.0145973594785344!GO:0008022;protein C-terminus binding;0.0146933969179173!GO:0016862;intramolecular oxidoreductase activity, interconverting keto- and enol-groups;0.0147835295453515!GO:0009967;positive regulation of signal transduction;0.0149475372603245!GO:0048487;beta-tubulin binding;0.0150848412170362!GO:0043022;ribosome binding;0.0151972138884081!GO:0030137;COPI-coated vesicle;0.0153356881789167!GO:0004722;protein serine/threonine phosphatase activity;0.0153715266245181!GO:0006220;pyrimidine nucleotide metabolic process;0.0155897056294416!GO:0035267;NuA4 histone acetyltransferase complex;0.0157222906712485!GO:0046467;membrane lipid biosynthetic process;0.0158393468447822!GO:0019783;small conjugating protein-specific protease activity;0.0158923880675655!GO:0016790;thiolester hydrolase activity;0.0170473804811771!GO:0000209;protein polyubiquitination;0.0170473804811771!GO:0051090;regulation of transcription factor activity;0.0177447245530438!GO:0022884;macromolecule transmembrane transporter activity;0.0179214323517705!GO:0015450;P-P-bond-hydrolysis-driven protein transmembrane transporter activity;0.0179214323517705!GO:0016627;oxidoreductase activity, acting on the CH-CH group of donors;0.0179214323517705!GO:0006611;protein export from nucleus;0.0179759516812777!GO:0007264;small GTPase mediated signal transduction;0.0179962749436819!GO:0043189;H4/H2A histone acetyltransferase complex;0.018091471705251!GO:0004843;ubiquitin-specific protease activity;0.0182252840129386!GO:0008320;protein transmembrane transporter activity;0.0185080996934447!GO:0042771;DNA damage response, signal transduction by p53 class mediator resulting in induction of apoptosis;0.0192180577056468!GO:0030518;steroid hormone receptor signaling pathway;0.0193619578230857!GO:0048037;cofactor binding;0.0195990389547898!GO:0008097;5S rRNA binding;0.0196079742363967!GO:0007021;tubulin folding;0.0196532985024188!GO:0030131;clathrin adaptor complex;0.0197872648661283!GO:0016197;endosome transport;0.0200898827605074!GO:0003725;double-stranded RNA binding;0.0203315140078417!GO:0006266;DNA ligation;0.0204106548941621!GO:0004576;oligosaccharyl transferase activity;0.0206460401532238!GO:0008538;proteasome activator activity;0.0208346663561803!GO:0032984;macromolecular complex disassembly;0.0209520270172764!GO:0009127;purine nucleoside monophosphate biosynthetic process;0.0215860448451774!GO:0009167;purine ribonucleoside monophosphate metabolic process;0.0215860448451774!GO:0009126;purine nucleoside monophosphate metabolic process;0.0215860448451774!GO:0009168;purine ribonucleoside monophosphate biosynthetic process;0.0215860448451774!GO:0005765;lysosomal membrane;0.0215860448451774!GO:0043281;regulation of caspase activity;0.0216222061449761!GO:0000139;Golgi membrane;0.0217416644647571!GO:0006635;fatty acid beta-oxidation;0.0221041976756054!GO:0031902;late endosome membrane;0.022626706810666!GO:0048518;positive regulation of biological process;0.0227404394814335!GO:0001726;ruffle;0.0229810613669806!GO:0022411;cellular component disassembly;0.0232703343296856!GO:0051656;establishment of organelle localization;0.0235745665084883!GO:0006301;postreplication repair;0.0235745665084883!GO:0006356;regulation of transcription from RNA polymerase I promoter;0.0235745665084883!GO:0000123;histone acetyltransferase complex;0.0236710901844459!GO:0033673;negative regulation of kinase activity;0.0237981843850181!GO:0006469;negative regulation of protein kinase activity;0.0237981843850181!GO:0006400;tRNA modification;0.0238457408060563!GO:0002763;positive regulation of myeloid leukocyte differentiation;0.0238457408060563!GO:0003702;RNA polymerase II transcription factor activity;0.0239009871849511!GO:0006506;GPI anchor biosynthetic process;0.0241151421909331!GO:0009889;regulation of biosynthetic process;0.0243051796443668!GO:0032039;integrator complex;0.0245982568350959!GO:0005669;transcription factor TFIID complex;0.0248628378457569!GO:0005869;dynactin complex;0.0250031718660562!GO:0000793;condensed chromosome;0.0253834904094585!GO:0000152;nuclear ubiquitin ligase complex;0.0254615800485927!GO:0008250;oligosaccharyl transferase complex;0.0257953286215937!GO:0032981;mitochondrial respiratory chain complex I assembly;0.0258396371172508!GO:0010257;NADH dehydrogenase complex assembly;0.0258396371172508!GO:0033108;mitochondrial respiratory chain complex assembly;0.0258396371172508!GO:0031625;ubiquitin protein ligase binding;0.0258457366789179!GO:0030134;ER to Golgi transport vesicle;0.0258620215242822!GO:0030508;thiol-disulfide exchange intermediate activity;0.0260752240460942!GO:0000080;G1 phase of mitotic cell cycle;0.0266471154468529!GO:0005652;nuclear lamina;0.0266525722000607!GO:0006783;heme biosynthetic process;0.0266957197831078!GO:0004659;prenyltransferase activity;0.027805793116754!GO:0004579;dolichyl-diphosphooligosaccharide-protein glycotransferase activity;0.0278761130142256!GO:0004221;ubiquitin thiolesterase activity;0.0279307259105714!GO:0004748;ribonucleoside-diphosphate reductase activity;0.0279841903634804!GO:0016728;oxidoreductase activity, acting on CH or CH2 groups, disulfide as acceptor;0.0279841903634804!GO:0043631;RNA polyadenylation;0.0280002027598571!GO:0005658;alpha DNA polymerase:primase complex;0.0282628538775437!GO:0016891;endoribonuclease activity, producing 5'-phosphomonoesters;0.0283955167063809!GO:0043549;regulation of kinase activity;0.0287936912308653!GO:0051235;maintenance of localization;0.0292162678997749!GO:0009083;branched chain family amino acid catabolic process;0.0296146392740485!GO:0006007;glucose catabolic process;0.0297666255831383!GO:0007004;telomere maintenance via telomerase;0.0300479389253284!GO:0030027;lamellipodium;0.0301410897573237!GO:0000910;cytokinesis;0.03044505470099!GO:0006505;GPI anchor metabolic process;0.0304811778794777!GO:0046426;negative regulation of JAK-STAT cascade;0.0307419777464749!GO:0008144;drug binding;0.0307789631027584!GO:0005720;nuclear heterochromatin;0.030840068174406!GO:0051348;negative regulation of transferase activity;0.0308782562768242!GO:0004448;isocitrate dehydrogenase activity;0.0308782562768242!GO:0033116;ER-Golgi intermediate compartment membrane;0.031042891429648!GO:0030218;erythrocyte differentiation;0.0312412135109856!GO:0030132;clathrin coat of coated pit;0.0312412135109856!GO:0006118;electron transport;0.031395815904799!GO:0042719;mitochondrial intermembrane space protein transporter complex;0.0318493516434426!GO:0045039;protein import into mitochondrial inner membrane;0.0318493516434426!GO:0043241;protein complex disassembly;0.0318804634230712!GO:0043624;cellular protein complex disassembly;0.0319302738725031!GO:0019206;nucleoside kinase activity;0.032053874321844!GO:0018193;peptidyl-amino acid modification;0.0320991450542171!GO:0005850;eukaryotic translation initiation factor 2 complex;0.0322650596926031!GO:0016044;membrane organization and biogenesis;0.03259388292242!GO:0030127;COPII vesicle coat;0.0328828067317282!GO:0012507;ER to Golgi transport vesicle membrane;0.0328828067317282!GO:0006890;retrograde vesicle-mediated transport, Golgi to ER;0.0332418674403482!GO:0005732;small nucleolar ribonucleoprotein complex;0.0342151915817879!GO:0048471;perinuclear region of cytoplasm;0.0343432963081749!GO:0006497;protein amino acid lipidation;0.0344247710197383!GO:0050681;androgen receptor binding;0.0344592933884171!GO:0045859;regulation of protein kinase activity;0.0347951587889496!GO:0000175;3'-5'-exoribonuclease activity;0.034863335358112!GO:0005096;GTPase activator activity;0.0350452835335101!GO:0005095;GTPase inhibitor activity;0.0351682172167559!GO:0051338;regulation of transferase activity;0.0351682172167559!GO:0005784;translocon complex;0.0359883867640793!GO:0016893;endonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters;0.0362432082551006!GO:0008017;microtubule binding;0.0365990752838527!GO:0051336;regulation of hydrolase activity;0.0367262307912723!GO:0005092;GDP-dissociation inhibitor activity;0.0372452615225997!GO:0022415;viral reproductive process;0.0373095795319317!GO:0032404;mismatch repair complex binding;0.0384976611328424!GO:0005874;microtubule;0.0393862615308191!GO:0050178;phenylpyruvate tautomerase activity;0.0397379297534531!GO:0006368;RNA elongation from RNA polymerase II promoter;0.0397703008301404!GO:0032405;MutLalpha complex binding;0.0397703008301404!GO:0051920;peroxiredoxin activity;0.0400559201433173!GO:0017069;snRNA binding;0.0403371917798535!GO:0017166;vinculin binding;0.0407002115034966!GO:0031577;spindle checkpoint;0.0407788185325491!GO:0033170;DNA-protein loading ATPase activity;0.0407788185325491!GO:0003689;DNA clamp loader activity;0.0407788185325491!GO:0042769;DNA damage response, detection of DNA damage;0.041262217149022!GO:0030433;ER-associated protein catabolic process;0.041541138073713!GO:0006515;misfolded or incompletely synthesized protein catabolic process;0.041541138073713!GO:0004523;ribonuclease H activity;0.0419653555298716!GO:0004239;methionyl aminopeptidase activity;0.0420127636138709!GO:0015035;protein disulfide oxidoreductase activity;0.0421225992166461!GO:0042026;protein refolding;0.0428315343132389!GO:0000805;X chromosome;0.0428315343132389!GO:0001740;Barr body;0.0428315343132389!GO:0000122;negative regulation of transcription from RNA polymerase II promoter;0.0429869707188896!GO:0008537;proteasome activator complex;0.0433565360088047!GO:0000097;sulfur amino acid biosynthetic process;0.0437561608567406!GO:0042809;vitamin D receptor binding;0.0439987696897923!GO:0030695;GTPase regulator activity;0.0442455275899883!GO:0051320;S phase;0.0446591811096969!GO:0017134;fibroblast growth factor binding;0.0452280497247356!GO:0009113;purine base biosynthetic process;0.0452421920516524!GO:0008287;protein serine/threonine phosphatase complex;0.0452821645940266!GO:0031371;ubiquitin conjugating enzyme complex;0.046515309777161!GO:0035259;glucocorticoid receptor binding;0.0467910160821567!GO:0003756;protein disulfide isomerase activity;0.0471906439696545!GO:0016864;intramolecular oxidoreductase activity, transposing S-S bonds;0.0471906439696545!GO:0051318;G1 phase;0.0475259250082607!GO:0030911;TPR domain binding;0.0475819881245246!GO:0008156;negative regulation of DNA replication;0.0475848672179985!GO:0006278;RNA-dependent DNA replication;0.0477313811744768!GO:0051219;phosphoprotein binding;0.0478722914210683!GO:0030174;regulation of DNA replication initiation;0.0481401218141504!GO:0009396;folic acid and derivative biosynthetic process;0.04841578146149!GO:0032507;maintenance of cellular protein localization;0.0488629833472256!GO:0009067;aspartate family amino acid biosynthetic process;0.0488677072419968!GO:0005528;FK506 binding;0.0488677072419968!GO:0005527;macrolide binding;0.0488677072419968!GO:0008652;amino acid biosynthetic process;0.049124914569151!GO:0030522;intracellular receptor-mediated signaling pathway;0.0495158598977064 | |||
|sample_id=10831 | |||
|sample_note= | |||
|sample_sex=female | |||
|sample_species=Human (Homo sapiens) | |||
|sample_strain= | |||
|sample_tissue=blood | |||
|top_motifs=PAX4:2.07953789872;YY1:1.69469659723;E2F1..5:1.5738767742;ALX1:1.50578694898;FOX{I1,J2}:1.3529437393;GATA6:1.21525800452;IKZF2:1.14929773385;TEF:1.12686522253;MYB:1.11979076133;ELF1,2,4:1.04323356621;ZBTB16:1.03229796035;PDX1:0.97238284352;ARID5B:0.971182463046;SPIB:0.965544485896;FOXP3:0.948598415977;PBX1:0.900561552307;ONECUT1,2:0.88359950571;PITX1..3:0.877293562549;CDX1,2,4:0.870116969145;DMAP1_NCOR{1,2}_SMARC:0.855648337371;NANOG:0.847314197489;ZNF143:0.813918551618;FOXQ1:0.788196254384;NANOG{mouse}:0.714499628108;SPI1:0.662744890803;HAND1,2:0.661562384426;RXR{A,B,G}_{NR1H2,PPAR}dimers:0.651362512569;POU1F1:0.625748136984;AIRE:0.616578781021;RXRA_VDR{dimer}:0.614304940496;NKX2-3_NKX2-5:0.593402586778;RUNX1..3:0.572486485743;BREu{core}:0.560984160054;TLX2:0.558164491057;CUX2:0.551926204196;NRF1:0.544265323838;PAX8:0.541938106671;NR5A1,2:0.516665268688;NFY{A,B,C}:0.47250441515;OCT4_SOX2{dimer}:0.429281959325;PAX6:0.420503475811;HOXA9_MEIS1:0.409686928504;FOXD3:0.396959596176;ETS1,2:0.390672429797;NKX6-1,2:0.379601429382;ZNF148:0.369408891308;ELK1,4_GABP{A,B1}:0.332633033103;TFDP1:0.325003340432;NKX3-2:0.305331649175;GCM1,2:0.301052923197;POU2F1..3:0.291959147358;RORA:0.279728804049;POU6F1:0.244108389139;RBPJ:0.241554133673;GATA4:0.217665408057;VSX1,2:0.147041518391;ARNT_ARNT2_BHLHB2_MAX_MYC_USF1:0.141888654804;FOXA2:0.139437599574;HOX{A4,D4}:0.137665912566;FOXP1:0.137548342365;IRF1,2:0.132183735052;TOPORS:0.131156114603;ESR1:0.130314891253;POU3F1..4:0.122680132422;NFIX:0.117092682525;SOX5:0.0646977475258;HES1:0.0527059720903;NKX2-1,4:0.043501729003;SNAI1..3:0.0336562871704;FOX{F1,F2,J1}:0.0325828709732;SOX17:0.0150020650652;NKX2-2,8:0.00956342427633;HBP1_HMGB_SSRP1_UBTF:0.00813906573087;T:-0.002889866035;FOXN1:-0.00897500645713;EVI1:-0.0196770048115;HNF4A_NR2F1,2:-0.026118958086;AR:-0.0332911421262;CRX:-0.0420619306424;LHX3,4:-0.0464383219188;BPTF:-0.0507747767849;STAT1,3:-0.0682988841013;EP300:-0.0684564300276;UFEwm:-0.0872400330429;PPARG:-0.0976139005516;STAT5{A,B}:-0.103227910704;ZNF384:-0.116403671418;NKX3-1:-0.116421014951;ZNF238:-0.11778246784;TGIF1:-0.126199982852;PRRX1,2:-0.130040890246;KLF4:-0.147767499194;MYBL2:-0.153301825731;PAX3,7:-0.155578495694;PAX1,9:-0.176909652835;HOX{A6,A7,B6,B7}:-0.185727179671;AHR_ARNT_ARNT2:-0.196101273338;RXR{A,B,G}:-0.200211858722;ZEB1:-0.231131495664;SOX{8,9,10}:-0.231570145211;POU5F1:-0.238258350003;HMGA1,2:-0.260948374242;HNF1A:-0.261340417309;bHLH_family:-0.26962921227;NR6A1:-0.282341466899;ATF5_CREB3:-0.328665347337;DBP:-0.376428022215;XBP1:-0.377586998688;NFKB1_REL_RELA:-0.383834397392;GFI1:-0.386271898383;MYOD1:-0.387102736957;LMO2:-0.421847379579;REST:-0.425618989841;RFX2..5_RFXANK_RFXAP:-0.426650420537;GZF1:-0.440017339187;RREB1:-0.44229292927;NFIL3:-0.443132309965;FOXM1:-0.445350465587;ZBTB6:-0.456780194367;FOSL2:-0.489384617052;HSF1,2:-0.495833146439;MEF2{A,B,C,D}:-0.512661191318;MZF1:-0.519793078323;EN1,2:-0.52374489671;NR1H4:-0.555138579669;PRDM1:-0.562947001002;NFE2:-0.5754734691;PAX2:-0.593472452823;TP53:-0.59525096731;LEF1_TCF7_TCF7L1,2:-0.599959773884;HOX{A5,B5}:-0.601550154546;SMAD1..7,9:-0.605104458191;IRF7:-0.608770727393;ZIC1..3:-0.619121024089;GTF2I:-0.624016743241;FOS_FOS{B,L1}_JUN{B,D}:-0.643341065302;BACH2:-0.650483982468;CEBPA,B_DDIT3:-0.651084508663;IKZF1:-0.65906111172;FOXO1,3,4:-0.670280446712;GTF2A1,2:-0.680878213971;MYFfamily:-0.693641609794;ZNF423:-0.696487110736;NFE2L2:-0.715645967435;ATF4:-0.721118362825;MED-1{core}:-0.73556981776;PATZ1:-0.741473423616;CREB1:-0.768284216612;SREBF1,2:-0.776862538214;HIC1:-0.791881184391;NHLH1,2:-0.793905147023;CDC5L:-0.805649450743;TFAP2B:-0.819846567959;TBX4,5:-0.840158897008;TFAP4:-0.856765056375;TFAP2{A,C}:-0.860403327552;PAX5:-0.861230964351;STAT2,4,6:-0.863059064401;SPZ1:-0.871744608361;EBF1:-0.876374798931;ATF2:-0.878790501888;ZFP161:-0.888583102403;MAZ:-0.911613186503;HMX1:-0.913907178255;NFATC1..3:-0.928913059528;HLF:-0.930825788104;FOX{D1,D2}:-0.973484876673;SOX2:-0.981962754917;ESRRA:-1.03679741378;NFE2L1:-1.0537582627;FOXL1:-1.08621245133;SRF:-1.09519979757;TEAD1:-1.096091569;RFX1:-1.09742313268;TBP:-1.10854479974;ALX4:-1.13247858998;TAL1_TCF{3,4,12}:-1.1645883548;EGR1..3:-1.16991637932;GLI1..3:-1.18021041764;MTE{core}:-1.21789479219;GFI1B:-1.22883278958;TLX1..3_NFIC{dimer}:-1.23543955323;NR3C1:-1.24151927559;XCPE1{core}:-1.29515661194;MAFB:-1.36062338876;MTF1:-1.3731649821;JUN:-1.68097163863;ADNP_IRX_SIX_ZHX:-1.68647584012;TFCP2:-1.69306322576;HIF1A:-1.75190328845;ATF6:-1.76264916721;SP1:-1.85441696882 | |||
|xref= | |||
|zenbu_report=https://fantom.gsc.riken.jp/zenbu/reports/#miRNA_expression_atlas_human;search_select_hide=table111:FF:10831-111D3;search_select_hide=table117:FF:10831-111D3 | |||
}} | }} |
Latest revision as of 15:08, 3 June 2020
Name: | acute myeloid leukemia (FAB M4) cell line:HNT-34 |
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Species: | Human (Homo sapiens) |
Library ID: | CNhs13504 |
Sample type: | cell lines |
Genomic View: | UCSC |
RefEX: | Specific genes |
CAGEd-oPOSSUM: | link |
ZENBU report : | link |
Additional information | ||||||||||||||||||||||||||||
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Sample information
RNA information
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CAGE Accession numbers | ||||||||||||||||||||||||||||||||||||||||||||||
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Download raw sequence, BAM & CTSS | ||||||||||||||
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Relative expression to median (log10)
Transcription factors with enriched expression in this sampleRanked list of transcription factor promoter expression in this sample relative to the median expression in the FANTOM5 collection is shown. Value is log10 transformed.
Co-expression clusters with enriched expression in this sampleRanked list of co-expression cluster expression in this sample relative to the median expression in the FANTOM5 collection is shown. Value is log10 transformed. <br>Analyst:NA <br><br>link to dataset.<br>data
Repeat families with enriched expression in this sample<b>Summary:</b>Ranked list of repeat family expression in this sample relative tothe median expression in the FANTOM5 collection is shown. Value is log10transformed.<br><b>Analyst:</b>NA<br><br>link to dataset.<br>data
TFBS(DNA)motifs over-represented in proximal region of promoters active in this sample
JASPAR motifs<b>Summary:</b>Association of JASPAR motif to the promoter expression in thissample. Pearson's correlation between the number of TFBSs estimated byusing the position-weight matrix for each promoter and its expression isexpressed as Z-score by taking the ones based on random position-weightmatrix, and the tail probability of the normal distribution correspondingto the Z-score is taken as the resulting P-value. Lower P-value indicatesmore (non-random) association of the motif to promoter expression<br><b>Analyst:</b> Michiel de Hoon <br><br><br>link to dataset.<br>data
library id: CNhs13504
FANTOM5 phase1 novel unique motifs<b>Summary:</b>Association of the 169 novel and unique motifs discovered in FANTOM5 phase1 in this sample. Among the de-novo motifs discovered by DMF, HOMER,ChIPMunk, and ScanAll, only novel motifs are selected after comparison with known motif sets, and their clustering based on MACRO-APE resulted in169 novel and unique motifs. Their association to the promoter expression is evaluated in the same way to the JASPAR motif above<br><b>Analyst:</b> Michiel de Hoon <br><br><br>link to dataset.<br>data
library id: CNhs13504
Novel motif | Logo | P-value |
---|---|---|
1 | 1 | 0.073 |
10 | 10 | 0.046 |
100 | 100 | 0.789 |
101 | 101 | 0.276 |
102 | 102 | 0.488 |
103 | 103 | 0.0723 |
104 | 104 | 0.639 |
105 | 105 | 0.825 |
106 | 106 | 0.963 |
107 | 107 | 0.777 |
108 | 108 | 0.841 |
109 | 109 | 0.133 |
11 | 11 | 0.0846 |
110 | 110 | 0.198 |
111 | 111 | 0.0485 |
112 | 112 | 0.861 |
113 | 113 | 0.76 |
114 | 114 | 0.029 |
115 | 115 | 0.447 |
116 | 116 | 0.266 |
117 | 117 | 0.0441 |
118 | 118 | 0.0488 |
119 | 119 | 0.693 |
12 | 12 | 0.66 |
120 | 120 | 0.253 |
121 | 121 | 0.259 |
122 | 122 | 0.954 |
123 | 123 | 0.00826 |
124 | 124 | 0.0046 |
125 | 125 | 0.0888 |
126 | 126 | 0.218 |
127 | 127 | 0.136 |
128 | 128 | 0.947 |
129 | 129 | 0.0577 |
13 | 13 | 0.0114 |
130 | 130 | 0.683 |
131 | 131 | 0.384 |
132 | 132 | 0.883 |
133 | 133 | 0.878 |
134 | 134 | 0.577 |
135 | 135 | 0.621 |
136 | 136 | 0.146 |
137 | 137 | 0.636 |
138 | 138 | 0.3 |
139 | 139 | 0.496 |
14 | 14 | 0.801 |
140 | 140 | 0.191 |
141 | 141 | 0.124 |
142 | 142 | 0.414 |
143 | 143 | 0.305 |
144 | 144 | 0.564 |
145 | 145 | 0.119 |
146 | 146 | 0.917 |
147 | 147 | 0.0536 |
148 | 148 | 0.224 |
149 | 149 | 0.816 |
15 | 15 | 0.28 |
150 | 150 | 0.788 |
151 | 151 | 0.8 |
152 | 152 | 0.25 |
153 | 153 | 0.8 |
154 | 154 | 0.897 |
155 | 155 | 0.0951 |
156 | 156 | 0.72 |
157 | 157 | 0.216 |
158 | 158 | 0.707 |
159 | 159 | 0.698 |
16 | 16 | 0.455 |
160 | 160 | 0.049 |
161 | 161 | 0.00837 |
162 | 162 | 0.584 |
163 | 163 | 0.986 |
164 | 164 | 0.335 |
165 | 165 | 0.448 |
166 | 166 | 0.705 |
167 | 167 | 0.0827 |
168 | 168 | 0.873 |
169 | 169 | 0.409 |
17 | 17 | 0.824 |
18 | 18 | 0.733 |
19 | 19 | 0.811 |
2 | 2 | 0.76 |
20 | 20 | 0.761 |
21 | 21 | 0.23 |
22 | 22 | 0.743 |
23 | 23 | 0.0251 |
24 | 24 | 0.104 |
25 | 25 | 0.288 |
26 | 26 | 0.0584 |
27 | 27 | 0.537 |
28 | 28 | 0.84 |
29 | 29 | 0.0532 |
3 | 3 | 0.0878 |
30 | 30 | 0.333 |
31 | 31 | 0.672 |
32 | 32 | 0.0787 |
33 | 33 | 0.182 |
34 | 34 | 0.862 |
35 | 35 | 0.154 |
36 | 36 | 0.0515 |
37 | 37 | 0.17 |
38 | 38 | 0.499 |
39 | 39 | 0.562 |
4 | 4 | 0.172 |
40 | 40 | 0.291 |
41 | 41 | 0.822 |
42 | 42 | 0.129 |
43 | 43 | 0.484 |
44 | 44 | 0.12 |
45 | 45 | 0.801 |
46 | 46 | 0.072 |
47 | 47 | 0.0449 |
48 | 48 | 0.0541 |
49 | 49 | 0.183 |
5 | 5 | 0.863 |
50 | 50 | 0.815 |
51 | 51 | 0.687 |
52 | 52 | 0.379 |
53 | 53 | 0.523 |
54 | 54 | 0.751 |
55 | 55 | 0.323 |
56 | 56 | 0.525 |
57 | 57 | 0.0562 |
58 | 58 | 0.193 |
59 | 59 | 0.381 |
6 | 6 | 0.582 |
60 | 60 | 0.962 |
61 | 61 | 0.11 |
62 | 62 | 0.129 |
63 | 63 | 0.595 |
64 | 64 | 0.232 |
65 | 65 | 0.544 |
66 | 66 | 0.0826 |
67 | 67 | 0.897 |
68 | 68 | 0.837 |
69 | 69 | 0.494 |
7 | 7 | 0.0318 |
70 | 70 | 0.304 |
71 | 71 | 0.0147 |
72 | 72 | 0.893 |
73 | 73 | 0.773 |
74 | 74 | 0.987 |
75 | 75 | 0.032 |
76 | 76 | 0.426 |
77 | 77 | 0.972 |
78 | 78 | 0.00476 |
79 | 79 | 0.0656 |
8 | 8 | 0.0354 |
80 | 80 | 0.185 |
81 | 81 | 0.419 |
82 | 82 | 0.601 |
83 | 83 | 0.784 |
84 | 84 | 0.689 |
85 | 85 | 0.421 |
86 | 86 | 0.748 |
87 | 87 | 0.779 |
88 | 88 | 0.285 |
89 | 89 | 0.841 |
9 | 9 | 0.912 |
90 | 90 | 0.0456 |
91 | 91 | 0.74 |
92 | 92 | 0.888 |
93 | 93 | 0.968 |
94 | 94 | 0.961 |
95 | 95 | 0.0819 |
96 | 96 | 0.838 |
97 | 97 | 0.336 |
98 | 98 | 0.159 |
99 | 99 | 0.772 |
de novo motifs identified by HOMER in promoters active in this sample<b>Summary:</b>The result of HOMER in this sample is shown.<br><b>Analyst:</b>NA <br>
library id: CNhs13504
FANTOM5 (FF) ontology
Direct parent terms
is_a relathionship
EFO:0002091 biological replicate
FF:0000210 human sample
FF:0101883 acute myeloid leukemia cell line sample
Ancestor terms (non development)<b>Summary:</b>Connected ontology terms with is_a, part_of or located_in relationship <br><b>Analyst:</b> Hideya Kawaji<br><br>link to source data<br>data
CL: Cell type
0000000 (cell), 0000000 (cell)
0000003 (native cell)
0000988 (hematopoietic cell)
0000548 (animal cell)
0000763 (myeloid cell)
0002371 (somatic cell)
0000255 (eukaryotic cell)
DOID: Disease
4 (disease)
0050686 (organ system cancer)
162 (cancer)
2531 (hematologic cancer)
14566 (disease of cellular proliferation)
0060083 (immune system cancer)
1240 (leukemia)
8692 (myeloid leukemia)
FF: FANTOM5
0000102 (sample by type)
0000003 (cell line sample)
0000210 (human sample)
0000101 (sample by species)
0000001 (sample)
0100737 (leukemia cell line sample)
0101035 (hematopoietic cell line sample)
0101883 (acute myeloid leukemia cell line sample)
0100740 (myeloid leukemia cell line sample)
Ancestor terms (development)<b>Summary:</b>Connected ontology terms with develops_from, derives_from or preceded_by relationship <br><b>Analyst:</b> Hideya Kawaji <br><br>link to source data<br>data
CL:0000049 (common myeloid progenitor)
CL:0000134 (mesenchymal cell)