FF:10834-111D6: Difference between revisions
From FANTOM5_SSTAR
(Created page with "{{f5samples
|id=FF:10834-111D6
|name=acute myeloid leukemia (FAB M5) cell line:U-937 DE-4, biol_rep1
|sample_id=10834
|rna_tube_id=
|rna_box=111
|rna_position=D6
|sampl...") |
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{{f5samples | {{f5samples | ||
| | |DRA_sample_Accession=CAGE@SAMD00004814 | ||
| | |accession_numbers=CAGE;DRX007816;DRR008688;DRZ000113;DRZ001498;DRZ011463;DRZ012848 | ||
| | |ancestors_in_anatomy_facet= | ||
| | |ancestors_in_cell_lineage_facet=CL:0000000,CL:0000003,CL:0000988,CL:0000548,CL:0000763,CL:0002371,CL:0000255 | ||
| | |ancestors_in_disease_facet=DOID:4,DOID:0050686,DOID:162,DOID:2531,DOID:14566,DOID:0060083,DOID:1240,DOID:8692 | ||
|ancestors_in_ff_facet=FF:0000102,FF:0000003,FF:0000210,FF:0000101,FF:0000001,FF:0100737,FF:0101035,FF:0101883,FF:0100740 | |||
| | |comment= | ||
| | |created_by= | ||
|creation_date= | |||
|data_phase=2 | |||
| | |datafreeze_phase=2 | ||
| | |def= | ||
| | |expression_enrichment_score=chr2:68592406..68592424,+!p1@PLEK!2.35!220.79!PLEK;;chr11:47400078..47400106,-!p1@SPI1!2.16!145.17!SPI1;;chr1:92949331..92949377,-!p2@GFI1!2.01!100.23!GFI1;;chr7:50344289..50344323,+!p1@IKZF1!1.98!93.59!IKZF1;;chr6:135502408..135502459,+!p2@MYB!1.93!95.94!MYB;;chr6:135502501..135502546,+!p1@MYB!1.84!80.89!MYB;;chr19:33793430..33793447,-!p1@CEBPA!1.76!228.80!CEBPA;;chr7:137620650..137620677,-!p3@CREB3L2!1.74!53.54!CREB3L2;;chr7:115670804..115670825,-!p1@TFEC!1.72!51.58!TFEC;;chr12:54694758..54694805,-!p1@NFE2!1.71!60.77!NFE2;;chr21:34442439..34442455,+!p1@OLIG1!1.70!49.24!OLIG1;;chr19:13213662..13213686,-!p1@LYL1!1.69!69.56!LYL1;;chr14:75988771..75988826,+!p1@BATF!1.67!59.98!BATF;;chr16:85932760..85932775,+!p1@IRF8!1.61!39.66!IRF8;;chr1:92951607..92951661,-!p1@GFI1!1.58!37.12!GFI1;;chr7:27224842..27224872,-!p1@HOXA11!1.57!35.95!HOXA11;;chr12:54778471..54778528,-!p1@ZNF385A!1.56!35.37!ZNF385A;;chr12:54694807..54694832,-!p3@NFE2!1.53!33.22!NFE2;;chr7:137620684..137620711,-!p4@CREB3L2!1.44!26.57!CREB3L2;;chr7:27205136..27205164,-!p1@HOXA9!1.44!26.38!HOXA9;;chr7:27224795..27224840,-!p2@HOXA11!1.38!23.06!HOXA11;;chr21:34442540..34442560,+!p2@OLIG1!1.32!19.73!OLIG1;;chr10:31288398..31288455,-!p2@ZNF438!1.29!21.49!ZNF438;;chr2:68592394..68592405,+!p2@PLEK!1.29!18.56!PLEK;;chr7:27213893..27213954,-!p1@HOXA10!1.25!16.80!HOXA10;;chr11:47400062..47400077,-!p2@SPI1!1.22!15.63!SPI1;;chr2:60780607..60780624,-!p2@BCL11A!1.20!45.13!BCL11A;;chr2:239148671..239148686,-!p1@HES6!1.18!51.97!HES6;;chr2:172949484..172949522,+!p1@DLX1!1.18!14.26!DLX1;;chr19:13213954..13214021,-!p4@LYL1!1.17!13.68!LYL1;;chr12:54694653..54694672,-!p2@NFE2!1.17!13.68!NFE2;;chr13:72441315..72441454,-!p1@DACH1!1.14!25.60!DACH1;;chr2:100759037..100759058,-!p2@AFF3!1.14!12.90!AFF3;;chr7:27192185..27192209,-!p1@HOXA3!1.14!12.70!HOXA3;;chr7:128577972..128578047,+!p1@IRF5!1.13!19.93!IRF5;;chr2:200322654..200322707,-!p2@SATB2!1.13!18.17!SATB2;;chr6:135502472..135502489,+!p3@MYB!1.12!12.11!MYB;;chr2:145277882..145277967,-!p3@ZEB2!1.10!20.32!ZEB2;;chr12:54410664..54410684,+!p1@HOXC4,p1@HOXC5,p1@HOXC6!1.10!11.53!HOXC5;;chr2:145277640..145277771,-!p1@ZEB2!1.08!147.52!ZEB2;;chr10:31288370..31288393,-!p3@ZNF438!1.08!11.14!ZNF438;;chr11:19262461..19262476,-!p5@E2F8!1.08!11.14!E2F8;;chr1:92952473..92952489,-!p3@GFI1!1.08!11.14!GFI1;;chr7:27205106..27205134,-!p2@HOXA9!1.08!10.94!HOXA9;;chr7:50344251..50344288,+!p3@IKZF1!1.06!10.55!IKZF1;;chr2:200320768..200320800,-!p4@SATB2!1.06!10.36!SATB2;;chr3:18486354..18486377,-!p2@SATB1!1.05!12.90!SATB1;;chr2:60778035..60778060,-!p4@BCL11A!1.05!12.31!BCL11A;;chr11:47399996..47400014,-!p4@SPI1!1.02!9.57!SPI1;;chr6:135516877..135516900,+!p5@MYB!1.01!9.18!MYB;;chr11:128563948..128564003,+!p1@FLI1!1.00!111.76!FLI1;;chr7:50343634..50343717,+!p2@IKZF1!1.00!8.99!IKZF1;;chr1:92949505..92949543,-!p5@GFI1!1.00!8.99!GFI1;;chr20:42295745..42295765,+!p1@MYBL2!0.98!142.44!MYBL2;;chr19:13213704..13213726,-!p3@LYL1!0.98!11.33!LYL1;;chr11:19263160..19263176,-!p1@E2F8!0.95!9.38!E2F8;;chr11:47400045..47400060,-!p6@SPI1!0.95!7.82!SPI1;;chr2:100759010..100759035,-!p1@AFF3!0.95!7.82!AFF3;;chr20:42295713..42295738,+!p2@MYBL2!0.94!47.09!MYBL2;;chr2:60780753..60780800,-!p1@BCL11A!0.94!38.88!BCL11A;;chr7:27239703..27239715,-!p1@HOXA13!0.94!7.62!HOXA13;;chr14:75988831..75988847,+!p2@BATF!0.90!7.03!BATF;;chr13:79177703..79177729,-!p2@POU4F1!0.90!7.03!POU4F1;;chr13:41593425..41593480,-!p1@ELF1!0.88!44.55!ELF1;;chr21:36421535..36421610,-!p2@RUNX1!0.88!24.81!RUNX1;;chr1:23857698..23857733,-!p1@E2F2!0.88!12.50!E2F2;;chr2:102091566..102091581,-!p1@RFX8!0.87!6.45!RFX8;;chr11:47399947..47399961,-!p3@SPI1!0.87!6.45!SPI1;;chr9:77112244..77112262,+!p1@RORB!0.86!7.03!RORB;;chr11:19263192..19263222,-!p2@E2F8!0.85!7.62!E2F8;;chr12:48298785..48298828,-!p1@VDR!0.82!32.04!VDR;;chr17:41277372..41277418,-!p1@BRCA1!0.82!21.69!BRCA1;;chr8:145669791..145669834,-!p1@TONSL!0.82!17.19!TONSL;;chr2:200322711..200322722,-!p10@SATB2!0.82!5.67!SATB2;;chr16:54320675..54320715,-!p1@IRX3!0.79!11.92!IRX3;;chr16:88752889..88752921,-!p1@SNAI3!0.79!6.06!SNAI3;;chr6:144385698..144385742,-!p2@PLAGL1!0.78!6.25!PLAGL1;;chr6:135513595..135513617,+!p4@MYB!0.78!5.08!MYB;;chr11:19262421..19262455,-!p3@E2F8!0.78!5.08!E2F8;;chr13:79177674..79177701,-!p1@POU4F1!0.77!4.88!POU4F1;;chr6:135516909..135516925,+!p6@MYB!0.77!4.88!MYB;;chr1:25256756..25256774,-!p1@RUNX3!0.76!9.38!RUNX3;;chr6:20402102..20402152,+!p1@E2F3!0.74!20.32!E2F3;;chr11:47400032..47400043,-!p5@SPI1!0.74!4.49!SPI1;;chr12:54410639..54410659,+!p2@HOXC4,p2@HOXC5,p2@HOXC6!0.74!4.49!HOXC5;;chr2:113977697..113977733,-!p6@PAX8!0.74!4.49!PAX8;;chr17:41623692..41623715,-!p1@ETV4!0.73!20.52!ETV4;;chr2:66662281..66662308,+!p1@MEIS1!0.72!16.22!MEIS1;;chr19:47538560..47538591,+!p2@NPAS1!0.72!4.30!NPAS1;;chr20:50159198..50159299,-!p1@NFATC2!0.71!6.25!NFATC2;;chr10:31146746..31146755,-!p14@ZNF438!0.71!4.10!ZNF438;;chr12:54380404..54380433,+!p3@HOXC10!0.71!4.10!HOXC10;;chr12:54694738..54694749,-!p5@NFE2!0.71!4.10!NFE2;;chr5:1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| ||
| | |ffid_belonging_in_development=CL:0000049,CL:0000134 | ||
| | |||
| | |||
|fonse_cell_line=FF:0101035 | |fonse_cell_line=FF:0101035 | ||
|fonse_cell_line_closure=FF:0101035 | |fonse_cell_line_closure=FF:0101035 | ||
Line 67: | Line 40: | ||
|fonse_treatment= | |fonse_treatment= | ||
|fonse_treatment_closure= | |fonse_treatment_closure= | ||
|has_quality= | |||
|hg19bam=http://fantom.gsc.riken.jp/5/datafiles/latest/basic/human.cell_line.hCAGE/acute%2520myeloid%2520leukemia%2520%2528FAB%2520M5%2529%2520cell%2520line%253aU-937%2520DE-4.CNhs13058.10834-111D6.hg19.nobarcode.bam | |||
|hg19ctss=http://fantom.gsc.riken.jp/5/datafiles/latest/basic/human.cell_line.hCAGE/acute%2520myeloid%2520leukemia%2520%2528FAB%2520M5%2529%2520cell%2520line%253aU-937%2520DE-4.CNhs13058.10834-111D6.hg19.ctss.bed.gz | |||
|hg19fasta=http://fantom.gsc.riken.jp/5/datafiles/latest/basic/human.cell_line.hCAGE/acute%2520myeloid%2520leukemia%2520%2528FAB%2520M5%2529%2520cell%2520line%253aU-937%2520DE-4.CNhs13058.10834-111D6.hg19.nobarcode.rdna.fa.gz | |||
|hg38bam=http://fantom.gsc.riken.jp/5/datafiles/reprocessed/hg38_v2/basic/human.cell_line.hCAGE/acute%2520myeloid%2520leukemia%2520%2528FAB%2520M5%2529%2520cell%2520line%253aU-937%2520DE-4.CNhs13058.10834-111D6.hg38.nobarcode.bam | |||
|hg38ctss=http://fantom.gsc.riken.jp/5/datafiles/reprocessed/hg38_v2/basic/human.cell_line.hCAGE/acute%2520myeloid%2520leukemia%2520%2528FAB%2520M5%2529%2520cell%2520line%253aU-937%2520DE-4.CNhs13058.10834-111D6.hg38.nobarcode.ctss.bed.gz | |||
|id=FF:10834-111D6 | |||
|is_a=EFO:0002091;;FF:0000210;;FF:0101883 | |||
|is_obsolete= | |||
|library_id=CNhs13058 | |||
|library_id_phase_based=2:CNhs13058 | |||
|microRNAs= | |||
|microRNAs_nn= | |||
|microRNAs_nonnovel_cage=http://fantom.gsc.riken.jp/5/suppl/De_Rie_et_al_2017/vis_viewer/#/human#cage;sample;10834 | |||
|microRNAs_novel_cage=http://fantom.gsc.riken.jp/5/suppl/De_Rie_et_al_2017/vis_viewer_novel/#/human#cage;sample;10834 | |||
|name=acute myeloid leukemia (FAB M5) cell line:U-937 DE-4 | |||
|namespace=FANTOM5 | |||
|part_of= | |||
|profile_cagescan=,,, | |||
|profile_hcage=CNhs13058,LSID1000,release012,COMPLETED | |||
|profile_rnaseq= | |||
|profile_srnaseq=,,, | |||
|refex=http://refex.dbcls.jp/genelist.php?lang | |||
|repeat_enrich_byfamily=0,0,0,0,0,0.200348167154155,0,0.0400301370677686,0.143257247232019,-0.131576050974072,0.14190745071388,0,0,0,0,0,0,0,0,0,0,0,0,0,-0.0100657631164091,0,0,0,0,0,-0.0204489697887544,0,0,0.0673915773752924,0,0,0,0,0,0,0,0,0,0,0,0,-0.0493916379118583,0,0,0,0,0,0,0,0,-0.0242150211128343,0,0,0,0.336925514468038,0,0,0,-0.019483434763302,0,0,0.153454968886757,0,0,0,0,0,0,0,0,0,0,0.0775089264793031,0,0,0.143257247232019,0,0,0,0,0,0,0,0,0,0,-0.419435156804479,0,0,0,0.0164671712179787,-0.0632006059487885,0,0,0,0,-0.0980353512377064,0.00951959594618525,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0.123962338058992,0.0775089264793031,0,0,-0.0997729947203204,-0.198610744597319,0,0,0,0,0,0 | |||
|repeat_enrich_byname=0,0,0,0.0775089264793031,-0.0980353512377064,0,0,0.250798596099854,0,0,0,0,0,0,0,0,-0.247178875285564,0,0.0241235462631129,0.0568330246306828,0.0716286236160095,0,-0.0998547282499805,0,0,0,0.0252276512816407,0,0,0,0,0,-0.128119866952565,0,0.0928446956427037,0,0,0,0,-0.0186252810838506,0.310079046510685,0,-0.0740839775724325,-0.0683442610773682,0,0,0,0,-0.131312122517595,0,-0.0433705573144375,0.254205346144621,-0.221611588102807,-0.494092920168616,-0.055712496781182,0,0,0,-0.544509709385122,0.380129401235365,0,0,-0.121779851751874,0.309869986291145,0,0,-0.391044581551635,0,-0.403162318602606,-0.248868050382253,0,0.357329286497461,0,0,0,0,0,0.143257247232019,0,0,0,0,0,-0.0574934668214365,-0.126640429524814,0.11284726639444,0,0,0,-0.46268105154519,0,0,0.242265121452525,-0.269631976484861,-0.030232669375406,0.100044810283696,0,0.138282136952994,0.0636744811688724,-0.313354244856909,-0.108348805159363,-0.147401849371139,-0.189981719549847,-0.00108427570986314,0.093045679984485,0.0623493934676316,0.0289825501314817,-0.295638097495106,0.0578943115193208,-0.507252446833978,-0.634054329931234,0,0,0,-0.356377429528836,0,0.0769997299958278,-0.0813483567681803,-0.141116715795178,-0.484236176488978,-0.229461408695094,-0.243452578602683,0.136795788978845,-0.0395325284566706,-0.457436452896595,-0.0447091474583761,0.0027386863871219,0,0.0775089264793031,-0.0877514257027229,-0.084011636147625,0.108325472972867,0.629883563083893,0,-0.109647730384617,0.182454335022486,0.0387544632396516,-0.0296626425058767,-0.0180537378435459,0,-0.0575569105386846,-0.501268304392109,0,0,0.213903842308843,0,0.250798596099854,0.0330488211482367,-0.339143975876012,-0.0325073944013901,0,-0.103817462077883,0.0387544632396516,-0.09290290149829,0,-0.153061187911254,-0.0685009709780911,-0.220565225881989,0.00389521079251787,0,0.0297085131430436,0.197575711132077,-0.174799476909834,-0.126401211897577,0.711277676765512,0.260420062850456,-0.0351409178645207,0.0164671712179787,0.126426171702168,0,0.207866761018873,-0.148229863355785,-0.474778392809787,-0.00625839773571935,-0.0671184743413296,-0.357610575276738,0,-0.395038893555252,0,-0.133600341890486,0,0.48324812377872,-0.099761887510333,0.560182740662871,0.673589938904644,0,-0.250106362910869,-0.788130937773974,0,-0.00015765040099458,-0.0609424593286269,0,-0.0728581568553362,-0.697695966512583,0.377949733589476,-0.100234993439543,0,-0.646822911157638,0,0,-0.374150216269177,0.10144947670365,0,-0.0189920184718773,0.0264414136387828,-0.055207229040921,-0.115971073434934,0.0775089264793031,0,-0.308774823524686,0.0488015400250079,0,-0.405579896663876,-0.0636048451378017,-0.419435156804479,-0.253326341486756,0,0.228302705013782,0,0,-0.177527765965176,0.690883485486872,0.15565133877434,0,0,-0.110952749782095,0,0,0.125399298049927,0,-0.0472688938106838,0,-0.0589565109853561,0,0,0,0,0,-0.0103699265847237,0.0539330274921453,0,0,0,0,0,0,0,-0.129406115216345,0,0,0.068002101494033,-0.0161356764825316,0.0202398315555983,0,0,0,0,-0.215723402553475,-0.125727635615421,0,-0.0543537800183286,0,0.0387544632396516,0,0,-0.0861409897892114,0,0,0,0,0.142617710100491,0.0303942300447013,0,0,0,0.0190391918923705,0,0,0,0,-0.0418139143636003,0,0,0,0,-0.027170991715308,0.0616753676851771,0,0.361024885838823,-0.236014989430039,-0.673976012796283,0,0.0775089264793031,-0.261347131789888,0,0,0.15868398068391,0,0,0,0,0,0,0,0,0,-0.071057265167737,0.0387544632396516,0,0,0,0,0.200348167154155,0,0.0775089264793031,0,0,0,-0.401263145950552,0.203769536835651,0,0,0,0,0,0,0,-0.0241060230789031,0.0246511685561065,0.0180645247757917,0,0,0,0,0,0,0,0.312484102581383,0,0,0,0,0,-0.019483434763302,0,0.0775089264793031,0,0,0.283814901427759,0,0,0.0595633822745243,0,0,0,0,0,0,0,0,0,0,0,0,0,0.0199381611965708,-0.18684131677012,0,0,0,0,0,0.143257247232019,0,-0.131576050974072,0,0,0,0,-0.113884373708977,0,0,0,0.0384608624428621,0,0.0400301370677686,0.200348167154155,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,-0.10549214416936,0,-0.00178810747697833,0,0,0,-0.232628352633041,0,0,0,0,0,0,0.0402881995874822,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0.0775089264793031,0,0,0,0,0,0,-0.0340979760341503,0,0,0,0,0,0,0,-0.0204489697887544,0,0,-0.0920328098005262,0,0,0,0,0,0,-0.0835936618024128,-0.144291853006419,-0.0255253632235602,0,0,0.0775089264793031,0.299533594665243,0.336925514468038,0,0,0,-0.0667773874189013,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,-0.0100657631164091,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0.0775089264793031,0.0387544632396516,0,0,0,0,0,0,-0.0340113632754165,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0.0387544632396516,0,0,0,0,0,0.170780127831215,0,0,0,-0.213086229657044,0,0,0,0,0,0,0.0775089264793031,0,0.143257247232019,0,0,0,0,0,0,0,0,0,0,0,0.0775089264793031,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,-0.20508069979624,0,0,0,0,0,0,0,0,0,0,0,0,0,-0.0482220752390542,0,-0.0843766322300271,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0.250798596099854,-0.254510449021551,0,0,0,0,0.0298718158183843,0,0,0,0,0,0,0,0.0767252634877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| |||
|rna_box=111 | |||
|rna_catalog_number= | |||
|rna_concentration=1.40434 | |||
|rna_extraction_protocol=OP-RNA-extraction-totalRNA-miRNeasy_Mini-v1.0 | |||
|rna_lot_number= | |||
|rna_od260/230=2.13 | |||
|rna_od260/280=2.08 | |||
|rna_position=D6 | |||
|rna_rin= | |||
|rna_sample_type=total RNA | |||
|rna_tube_id=111D6 | |||
|rna_weight_ug=126.3906 | |||
|sample_age=37 | |||
|sample_category=cell lines | |||
|sample_cell_catalog=RCB0435 | |||
|sample_cell_line=U-937 DE-4 | |||
|sample_cell_lot= | |||
|sample_cell_type=monoblast | |||
|sample_collaboration=Yukio Nakamura (RIKEN BRC) | |||
|sample_company=RIKEN Bioresource centre | |||
|sample_description= | |||
|sample_dev_stage= | |||
|sample_disease=acute myeloid leukemia (FAB M5) | |||
|sample_donor(cell lot)= | |||
|sample_ethnicity=unknown | |||
|sample_experimental_condition= | |||
|sample_gostat=GO:0044464;cell part;0!GO:0005622;intracellular;0!GO:0044424;intracellular part;3.54047557257489e-235!GO:0043227;membrane-bound organelle;3.01065119591071e-203!GO:0043231;intracellular membrane-bound organelle;8.00813577311593e-203!GO:0043226;organelle;6.96936505672051e-192!GO:0043229;intracellular organelle;3.7345247267152e-191!GO:0005737;cytoplasm;6.50986868909426e-168!GO:0044422;organelle part;9.24460005530634e-165!GO:0044446;intracellular organelle part;1.06749631738735e-162!GO:0044444;cytoplasmic part;2.67805513556568e-125!GO:0032991;macromolecular complex;7.37776618649424e-124!GO:0030529;ribonucleoprotein complex;1.35276826001033e-106!GO:0044237;cellular metabolic process;4.90597418166271e-102!GO:0044428;nuclear part;9.63578482634952e-100!GO:0044238;primary metabolic process;7.45576856861569e-96!GO:0043233;organelle lumen;2.36962535075331e-93!GO:0031974;membrane-enclosed lumen;2.36962535075331e-93!GO:0003723;RNA binding;6.82634666979475e-92!GO:0005739;mitochondrion;3.69703214434903e-89!GO:0005634;nucleus;4.69962371860357e-87!GO:0043170;macromolecule metabolic process;5.72694441679307e-86!GO:0006396;RNA processing;2.74414498358897e-71!GO:0006412;translation;2.59910199771633e-65!GO:0044429;mitochondrial part;1.01964596062768e-61!GO:0043234;protein complex;2.42386892433382e-61!GO:0005840;ribosome;1.20204583950799e-60!GO:0031981;nuclear lumen;8.36498681155675e-57!GO:0009058;biosynthetic process;3.69479321556214e-55!GO:0005515;protein binding;5.10076690045461e-55!GO:0031967;organelle envelope;1.06499515877195e-54!GO:0044249;cellular biosynthetic process;1.34493184176397e-54!GO:0031975;envelope;2.71210748817057e-54!GO:0003735;structural constituent of ribosome;1.71960746094755e-53!GO:0009059;macromolecule biosynthetic process;2.2383340509647e-50!GO:0019538;protein metabolic process;1.48156083165165e-49!GO:0016071;mRNA metabolic process;2.2387295800063e-49!GO:0006259;DNA metabolic process;4.52509460084692e-48!GO:0008380;RNA splicing;9.13785589659909e-47!GO:0043283;biopolymer metabolic process;1.07980297529943e-46!GO:0031090;organelle membrane;3.35304903929932e-46!GO:0044267;cellular protein metabolic process;4.09050974479755e-46!GO:0044260;cellular macromolecule metabolic process;5.07642308248586e-46!GO:0033279;ribosomal subunit;1.3172381747233e-45!GO:0006139;nucleobase, nucleoside, nucleotide and nucleic acid metabolic process;3.68080777346306e-45!GO:0022613;ribonucleoprotein complex biogenesis and assembly;1.45438202942023e-44!GO:0006397;mRNA processing;4.56545512611332e-44!GO:0016043;cellular component organization and biogenesis;1.18617754611565e-41!GO:0010467;gene expression;3.56102582927754e-40!GO:0005829;cytosol;6.16532854200843e-39!GO:0005740;mitochondrial envelope;1.16615679751614e-38!GO:0033036;macromolecule localization;1.49875522451849e-38!GO:0006996;organelle organization and biogenesis;3.03091054085378e-37!GO:0019866;organelle inner membrane;3.32147378519561e-37!GO:0015031;protein transport;8.04723238032486e-36!GO:0031966;mitochondrial membrane;8.04723238032486e-36!GO:0043228;non-membrane-bound organelle;1.75171327488897e-35!GO:0043232;intracellular non-membrane-bound organelle;1.75171327488897e-35!GO:0065003;macromolecular complex assembly;1.30435654171673e-34!GO:0045184;establishment of protein localization;2.24255596535019e-34!GO:0005743;mitochondrial inner membrane;2.32285137172978e-34!GO:0005681;spliceosome;2.37809293097081e-34!GO:0008104;protein localization;9.41334550835815e-34!GO:0007049;cell cycle;4.78419793300901e-33!GO:0005654;nucleoplasm;5.81179996321824e-33!GO:0000166;nucleotide binding;6.84868695796357e-32!GO:0005830;cytosolic ribosome (sensu Eukaryota);4.55014915193063e-31!GO:0046907;intracellular transport;2.14745068177252e-30!GO:0022607;cellular component assembly;3.29176062813361e-29!GO:0005694;chromosome;5.47648893612602e-29!GO:0006974;response to DNA damage stimulus;6.84197354736317e-29!GO:0031980;mitochondrial lumen;1.79670743477571e-27!GO:0005759;mitochondrial matrix;1.79670743477571e-27!GO:0044445;cytosolic part;2.1526298820794e-27!GO:0022402;cell cycle process;3.24164151313841e-27!GO:0000278;mitotic cell cycle;4.82057886380357e-27!GO:0006281;DNA repair;2.98933643261638e-26!GO:0044427;chromosomal part;8.28543008600992e-26!GO:0006886;intracellular protein transport;9.98628107468546e-26!GO:0044451;nucleoplasm part;1.36893834355499e-25!GO:0003676;nucleic acid binding;2.4517300985863e-25!GO:0005730;nucleolus;2.86643317387848e-25!GO:0006119;oxidative phosphorylation;2.90359108177982e-25!GO:0015934;large ribosomal subunit;3.03314855102035e-24!GO:0044455;mitochondrial membrane part;3.9121711316336e-24!GO:0051649;establishment of cellular localization;3.93163139580402e-24!GO:0022403;cell cycle phase;7.2593499568942e-24!GO:0051641;cellular localization;2.74734672109151e-23!GO:0042254;ribosome biogenesis and assembly;9.33208213818734e-23!GO:0000087;M phase of mitotic cell cycle;1.46326284965774e-22!GO:0015935;small ribosomal subunit;1.68440711671581e-22!GO:0022618;protein-RNA complex assembly;2.64497070978427e-22!GO:0016462;pyrophosphatase activity;3.21717023574576e-22!GO:0016818;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides;3.28366802547329e-22!GO:0051276;chromosome organization and biogenesis;4.24531583416302e-22!GO:0007067;mitosis;4.4069575571364e-22!GO:0016817;hydrolase activity, acting on acid anhydrides;4.4069575571364e-22!GO:0017076;purine nucleotide binding;5.6998722867436e-22!GO:0016874;ligase activity;5.74478559870601e-22!GO:0017111;nucleoside-triphosphatase activity;7.34177178011363e-22!GO:0032553;ribonucleotide binding;1.3844516932558e-21!GO:0032555;purine ribonucleotide binding;1.3844516932558e-21!GO:0005524;ATP binding;4.13674651153036e-21!GO:0030554;adenyl nucleotide binding;5.47582148576443e-21!GO:0032559;adenyl ribonucleotide binding;7.97786470556228e-21!GO:0000279;M phase;1.77272064058052e-20!GO:0006260;DNA replication;3.81886755579494e-20!GO:0006457;protein folding;6.94703225781039e-20!GO:0051301;cell division;1.3469922204139e-19!GO:0005746;mitochondrial respiratory chain;1.90906367810342e-19!GO:0051186;cofactor metabolic process;3.72362414566378e-19!GO:0005761;mitochondrial ribosome;3.92892477735006e-19!GO:0000313;organellar ribosome;3.92892477735006e-19!GO:0009719;response to endogenous stimulus;5.40970995086138e-19!GO:0044265;cellular macromolecule catabolic process;6.27556126645842e-19!GO:0016887;ATPase activity;1.24086263525517e-18!GO:0044248;cellular catabolic process;4.18371348992512e-18!GO:0006399;tRNA metabolic process;6.18954552187923e-18!GO:0042623;ATPase activity, coupled;7.83320751503458e-18!GO:0000398;nuclear mRNA splicing, via spliceosome;1.16053495075446e-17!GO:0000375;RNA splicing, via transesterification reactions;1.16053495075446e-17!GO:0000377;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile;1.16053495075446e-17!GO:0000502;proteasome complex (sensu Eukaryota);1.17003678338799e-17!GO:0008135;translation factor activity, nucleic acid binding;1.32197168815018e-17!GO:0016655;oxidoreductase activity, acting on NADH or NADPH, quinone or similar compound as acceptor;2.65682323522924e-17!GO:0050136;NADH dehydrogenase (quinone) activity;6.10037553221094e-17!GO:0003954;NADH dehydrogenase activity;6.10037553221094e-17!GO:0008137;NADH dehydrogenase (ubiquinone) activity;6.10037553221094e-17!GO:0006325;establishment and/or maintenance of chromatin architecture;7.92875627249904e-17!GO:0009057;macromolecule catabolic process;1.40588632858181e-16!GO:0043285;biopolymer catabolic process;1.52189501072396e-16!GO:0005635;nuclear envelope;1.84811907534441e-16!GO:0044453;nuclear membrane part;2.01564835218714e-16!GO:0006512;ubiquitin cycle;2.40090190120848e-16!GO:0006323;DNA packaging;2.92292311304789e-16!GO:0005842;cytosolic large ribosomal subunit (sensu Eukaryota);3.55162676373232e-16!GO:0006364;rRNA processing;7.08738850506885e-16!GO:0031965;nuclear membrane;8.48972508427867e-16!GO:0012505;endomembrane system;1.34936817791574e-15!GO:0016604;nuclear body;1.51857224932574e-15!GO:0016072;rRNA metabolic process;1.77264689720504e-15!GO:0042775;organelle ATP synthesis coupled electron transport;2.01880339646448e-15!GO:0042773;ATP synthesis coupled electron transport;2.01880339646448e-15!GO:0006732;coenzyme metabolic process;3.03415663864832e-15!GO:0005843;cytosolic small ribosomal subunit (sensu Eukaryota);4.984977938979e-15!GO:0006913;nucleocytoplasmic transport;5.69886457216853e-15!GO:0030964;NADH dehydrogenase complex (quinone);7.34163356126058e-15!GO:0045271;respiratory chain complex I;7.34163356126058e-15!GO:0005747;mitochondrial respiratory chain complex I;7.34163356126058e-15!GO:0006605;protein targeting;7.6345216843911e-15!GO:0003743;translation initiation factor activity;1.35782028764992e-14!GO:0016070;RNA metabolic process;1.38067003513576e-14!GO:0051169;nuclear transport;1.8752114570914e-14!GO:0050657;nucleic acid transport;1.99488715629767e-14!GO:0051236;establishment of RNA localization;1.99488715629767e-14!GO:0050658;RNA transport;1.99488715629767e-14!GO:0006120;mitochondrial electron transport, NADH to ubiquinone;2.15938560769802e-14!GO:0006403;RNA localization;2.47703242630716e-14!GO:0006413;translational initiation;3.21854372120167e-14!GO:0051082;unfolded protein binding;5.40398099859426e-14!GO:0048770;pigment granule;5.4258933477469e-14!GO:0042470;melanosome;5.4258933477469e-14!GO:0005643;nuclear pore;6.36365133116908e-14!GO:0051603;proteolysis involved in cellular protein catabolic process;1.79336197061047e-13!GO:0006511;ubiquitin-dependent protein catabolic process;2.41651695344154e-13!GO:0019941;modification-dependent protein catabolic process;2.4959639934812e-13!GO:0043632;modification-dependent macromolecule catabolic process;2.4959639934812e-13!GO:0044257;cellular protein catabolic process;3.64938845659173e-13!GO:0043412;biopolymer modification;5.55753108105572e-13!GO:0004386;helicase activity;6.86517494600064e-13!GO:0016876;ligase activity, forming aminoacyl-tRNA and related compounds;7.19690316520506e-13!GO:0004812;aminoacyl-tRNA ligase activity;7.19690316520506e-13!GO:0016875;ligase activity, forming carbon-oxygen bonds;7.19690316520506e-13!GO:0016651;oxidoreductase activity, acting on NADH or NADPH;9.15634642727575e-13!GO:0009259;ribonucleotide metabolic process;1.31689996281997e-12!GO:0000785;chromatin;1.59140704247051e-12!GO:0043038;amino acid activation;1.70967164957383e-12!GO:0006418;tRNA aminoacylation for protein translation;1.70967164957383e-12!GO:0043039;tRNA aminoacylation;1.70967164957383e-12!GO:0065002;intracellular protein transport across a membrane;2.20039186073114e-12!GO:0051726;regulation of cell cycle;2.26029241576232e-12!GO:0006446;regulation of translational initiation;2.28838416521268e-12!GO:0051028;mRNA transport;2.54576394978077e-12!GO:0000074;regulation of progression through cell cycle;3.03671329712913e-12!GO:0006163;purine nucleotide metabolic process;3.07249456672911e-12!GO:0046930;pore complex;4.22433379776279e-12!GO:0009260;ribonucleotide biosynthetic process;6.0209093647127e-12!GO:0015931;nucleobase, nucleoside, nucleotide and nucleic acid transport;7.32891353531146e-12!GO:0006164;purine nucleotide biosynthetic process;7.97947788079749e-12!GO:0000775;chromosome, pericentric region;8.20959921865129e-12!GO:0008026;ATP-dependent helicase activity;8.7181691769686e-12!GO:0006333;chromatin assembly or disassembly;9.07596667679865e-12!GO:0008134;transcription factor binding;1.13880446457148e-11!GO:0016779;nucleotidyltransferase activity;1.15032811115255e-11!GO:0030163;protein catabolic process;1.38866676550641e-11!GO:0016607;nuclear speck;1.40339271242928e-11!GO:0012501;programmed cell death;1.68395844331847e-11!GO:0006915;apoptosis;1.75137618674684e-11!GO:0009150;purine ribonucleotide metabolic process;2.43324952872339e-11!GO:0044432;endoplasmic reticulum part;3.42564813686133e-11!GO:0016568;chromatin modification;3.54211163373534e-11!GO:0009060;aerobic respiration;6.15931978402693e-11!GO:0009152;purine ribonucleotide biosynthetic process;6.26802424980013e-11!GO:0065004;protein-DNA complex assembly;6.52243975683357e-11!GO:0009056;catabolic process;7.98716132032216e-11!GO:0051188;cofactor biosynthetic process;8.38518449891695e-11!GO:0017038;protein import;8.66565889712558e-11!GO:0030532;small nuclear ribonucleoprotein complex;9.24556401914375e-11!GO:0009055;electron carrier activity;9.89538077818263e-11!GO:0006464;protein modification process;1.20681931466738e-10!GO:0046961;hydrogen ion transporting ATPase activity, rotational mechanism;1.60262008792068e-10!GO:0006261;DNA-dependent DNA replication;1.63427642987532e-10!GO:0016591;DNA-directed RNA polymerase II, holoenzyme;2.12698473038468e-10!GO:0008219;cell death;2.2301216660594e-10!GO:0016265;death;2.2301216660594e-10!GO:0016787;hydrolase activity;2.40905314686617e-10!GO:0003697;single-stranded DNA binding;2.42017808508256e-10!GO:0055086;nucleobase, nucleoside and nucleotide metabolic process;3.51173040814265e-10!GO:0045333;cellular respiration;5.0155420866403e-10!GO:0005783;endoplasmic reticulum;7.38151029781364e-10!GO:0046933;hydrogen ion transporting ATP synthase activity, rotational mechanism;1.11149408447888e-09!GO:0043566;structure-specific DNA binding;2.04020259881906e-09!GO:0016740;transferase activity;3.12535978589873e-09!GO:0048193;Golgi vesicle transport;3.34662315037708e-09!GO:0016879;ligase activity, forming carbon-nitrogen bonds;3.43124714503232e-09!GO:0015986;ATP synthesis coupled proton transport;3.73760989847723e-09!GO:0015985;energy coupled proton transport, down electrochemical gradient;3.73760989847723e-09!GO:0006099;tricarboxylic acid cycle;4.18360398339337e-09!GO:0046356;acetyl-CoA catabolic process;4.18360398339337e-09!GO:0008565;protein transporter activity;4.22915049682315e-09!GO:0019829;cation-transporting ATPase activity;4.30643829253751e-09!GO:0006084;acetyl-CoA metabolic process;4.78484621663561e-09!GO:0003899;DNA-directed RNA polymerase activity;4.85529581521287e-09!GO:0009117;nucleotide metabolic process;6.81021373159715e-09!GO:0009141;nucleoside triphosphate metabolic process;8.63932490251471e-09!GO:0043687;post-translational protein modification;8.83860227040543e-09!GO:0009199;ribonucleoside triphosphate metabolic process;8.90853713397167e-09!GO:0051246;regulation of protein metabolic process;1.34891889879855e-08!GO:0042175;nuclear envelope-endoplasmic reticulum network;1.41721693602619e-08!GO:0009142;nucleoside triphosphate biosynthetic process;1.63090283438198e-08!GO:0009201;ribonucleoside triphosphate biosynthetic process;1.63090283438198e-08!GO:0000075;cell cycle checkpoint;1.7950464933171e-08!GO:0005819;spindle;1.79785931645825e-08!GO:0009205;purine ribonucleoside triphosphate metabolic process;1.93622628336785e-08!GO:0009144;purine nucleoside triphosphate metabolic process;1.93622628336785e-08!GO:0009108;coenzyme biosynthetic process;2.13944003708787e-08!GO:0006334;nucleosome assembly;2.16705964762374e-08!GO:0046034;ATP metabolic process;2.56826895406983e-08!GO:0005789;endoplasmic reticulum membrane;3.03720786432825e-08!GO:0006754;ATP biosynthetic process;3.18079802499175e-08!GO:0006753;nucleoside phosphate metabolic process;3.18079802499175e-08!GO:0008639;small protein conjugating enzyme activity;3.34393194389544e-08!GO:0005839;proteasome core complex (sensu Eukaryota);3.34393194389544e-08!GO:0009206;purine ribonucleoside triphosphate biosynthetic process;3.59751294144794e-08!GO:0009145;purine nucleoside triphosphate biosynthetic process;3.59751294144794e-08!GO:0015078;hydrogen ion transmembrane transporter activity;4.01088955843878e-08!GO:0006461;protein complex assembly;4.44838101551929e-08!GO:0005657;replication fork;6.39589996443666e-08!GO:0031497;chromatin assembly;6.6150628803994e-08!GO:0009109;coenzyme catabolic process;7.2095111425958e-08!GO:0016469;proton-transporting two-sector ATPase complex;7.95431202543829e-08!GO:0000245;spliceosome assembly;8.23722433266999e-08!GO:0004842;ubiquitin-protein ligase activity;8.8649292140267e-08!GO:0051187;cofactor catabolic process;9.5532605296695e-08!GO:0003712;transcription cofactor activity;1.19520007589985e-07!GO:0008094;DNA-dependent ATPase activity;1.44342488184048e-07!GO:0051170;nuclear import;1.51842974488818e-07!GO:0006752;group transfer coenzyme metabolic process;1.58360346595378e-07!GO:0019787;small conjugating protein ligase activity;1.64824531670871e-07!GO:0015630;microtubule cytoskeleton;1.71733976926533e-07!GO:0007005;mitochondrion organization and biogenesis;1.73248350003954e-07!GO:0051329;interphase of mitotic cell cycle;1.75130363673665e-07!GO:0016192;vesicle-mediated transport;1.84094190653656e-07!GO:0051325;interphase;2.19359409287455e-07!GO:0007051;spindle organization and biogenesis;2.23386956369097e-07!GO:0045259;proton-transporting ATP synthase complex;2.66759395250598e-07!GO:0031202;RNA splicing factor activity, transesterification mechanism;3.36944705431034e-07!GO:0004298;threonine endopeptidase activity;3.53120054836265e-07!GO:0003724;RNA helicase activity;4.17370155370996e-07!GO:0051168;nuclear export;4.40433488585628e-07!GO:0006606;protein import into nucleus;4.6065988395103e-07!GO:0042981;regulation of apoptosis;4.82598434529194e-07!GO:0005813;centrosome;5.13900072309856e-07!GO:0005762;mitochondrial large ribosomal subunit;5.19782007459646e-07!GO:0000315;organellar large ribosomal subunit;5.19782007459646e-07!GO:0016741;transferase activity, transferring one-carbon groups;6.17873061224493e-07!GO:0044452;nucleolar part;6.38180767215948e-07!GO:0043067;regulation of programmed cell death;6.7211624059803e-07!GO:0008033;tRNA processing;6.72563733686481e-07!GO:0005793;ER-Golgi intermediate compartment;7.38204891386078e-07!GO:0005815;microtubule organizing center;1.08175949356176e-06!GO:0005794;Golgi apparatus;1.13332467348305e-06!GO:0016881;acid-amino acid ligase activity;1.18166759462434e-06!GO:0008168;methyltransferase activity;1.20909381143141e-06!GO:0006082;organic acid metabolic process;1.29661487875206e-06!GO:0019752;carboxylic acid metabolic process;1.29976868493881e-06!GO:0006302;double-strand break repair;1.57244972431333e-06!GO:0004518;nuclease activity;1.6078087434711e-06!GO:0016491;oxidoreductase activity;1.88428090635821e-06!GO:0016363;nuclear matrix;1.89186352948754e-06!GO:0006888;ER to Golgi vesicle-mediated transport;2.1418794511447e-06!GO:0016853;isomerase activity;2.30108531776265e-06!GO:0006793;phosphorus metabolic process;2.33632130695663e-06!GO:0006796;phosphate metabolic process;2.33632130695663e-06!GO:0006401;RNA catabolic process;2.5256939129867e-06!GO:0007059;chromosome segregation;3.21771200099324e-06!GO:0000314;organellar small ribosomal subunit;3.91820739835555e-06!GO:0005763;mitochondrial small ribosomal subunit;3.91820739835555e-06!GO:0032446;protein modification by small protein conjugation;3.95386879282944e-06!GO:0015077;monovalent inorganic cation transmembrane transporter activity;4.45426079461189e-06!GO:0006091;generation of precursor metabolites and energy;4.8597612235272e-06!GO:0000776;kinetochore;6.41942406566747e-06!GO:0016567;protein ubiquitination;7.08359668887614e-06!GO:0006310;DNA recombination;7.5119228409475e-06!GO:0006950;response to stress;7.57976092395538e-06!GO:0016310;phosphorylation;7.57976092395538e-06!GO:0009165;nucleotide biosynthetic process;9.55987201283667e-06!GO:0006366;transcription from RNA polymerase II promoter;9.61080936080307e-06!GO:0043623;cellular protein complex assembly;1.01820612500374e-05!GO:0046483;heterocycle metabolic process;1.20458151071952e-05!GO:0006520;amino acid metabolic process;1.22562473590527e-05!GO:0005773;vacuole;1.24049308207532e-05!GO:0000786;nucleosome;1.26310552159819e-05!GO:0006613;cotranslational protein targeting to membrane;1.26563433252516e-05!GO:0008654;phospholipid biosynthetic process;1.37260743687166e-05!GO:0030880;RNA polymerase complex;1.45603192837859e-05!GO:0003713;transcription coactivator activity;1.49757500880039e-05!GO:0042625;ATPase activity, coupled to transmembrane movement of ions;1.60995687609049e-05!GO:0000323;lytic vacuole;1.65039658379188e-05!GO:0005764;lysosome;1.65039658379188e-05!GO:0015405;P-P-bond-hydrolysis-driven transmembrane transporter activity;1.86946056724133e-05!GO:0015399;primary active transmembrane transporter activity;1.86946056724133e-05!GO:0007088;regulation of mitosis;2.1061322336136e-05!GO:0016772;transferase activity, transferring phosphorus-containing groups;2.12083367301658e-05!GO:0000151;ubiquitin ligase complex;2.50697205717458e-05!GO:0008186;RNA-dependent ATPase activity;2.57060827216869e-05!GO:0003684;damaged DNA binding;2.63117884896331e-05!GO:0043021;ribonucleoprotein binding;2.84185913551486e-05!GO:0045454;cell redox homeostasis;3.17715440637168e-05!GO:0006626;protein targeting to mitochondrion;3.23021814484738e-05!GO:0030120;vesicle coat;3.31489833109319e-05!GO:0030662;coated vesicle membrane;3.31489833109319e-05!GO:0055029;nuclear DNA-directed RNA polymerase complex;3.89512781419916e-05!GO:0000428;DNA-directed RNA polymerase complex;3.89512781419916e-05!GO:0006405;RNA export from nucleus;4.36595133257366e-05!GO:0048475;coated membrane;4.39046245444497e-05!GO:0030117;membrane coat;4.39046245444497e-05!GO:0030530;heterogeneous nuclear ribonucleoprotein complex;4.39393906383674e-05!GO:0005768;endosome;4.4745142882404e-05!GO:0006383;transcription from RNA polymerase III promoter;4.61723490166645e-05!GO:0003690;double-stranded DNA binding;5.32057276821224e-05!GO:0043681;protein import into mitochondrion;5.59034303905831e-05!GO:0004527;exonuclease activity;6.4332820316115e-05!GO:0032508;DNA duplex unwinding;6.50198879669722e-05!GO:0032392;DNA geometric change;6.50198879669722e-05!GO:0006916;anti-apoptosis;6.51487890273585e-05!GO:0004004;ATP-dependent RNA helicase activity;8.07833184639031e-05!GO:0005753;mitochondrial proton-transporting ATP synthase complex;9.38168311200629e-05!GO:0051052;regulation of DNA metabolic process;9.59264982094616e-05!GO:0007093;mitotic cell cycle checkpoint;9.87965338175949e-05!GO:0015980;energy derivation by oxidation of organic compounds;0.000116605986927259!GO:0006268;DNA unwinding during replication;0.000122476200930487!GO:0003729;mRNA binding;0.000142870990561323!GO:0005667;transcription factor complex;0.000145446751866692!GO:0006414;translational elongation;0.000147899591700643!GO:0003678;DNA helicase activity;0.000162218573834624!GO:0003682;chromatin binding;0.000163438463504291!GO:0005788;endoplasmic reticulum lumen;0.000164620439543392!GO:0000082;G1/S transition of mitotic cell cycle;0.000168323951560248!GO:0019899;enzyme binding;0.000179174300996521!GO:0006818;hydrogen transport;0.000179536576256934!GO:0015992;proton transport;0.000196927843795173!GO:0000049;tRNA binding;0.000202966508518729!GO:0009112;nucleobase metabolic process;0.000203913672345292!GO:0046474;glycerophospholipid biosynthetic process;0.000218161799464232!GO:0006519;amino acid and derivative metabolic process;0.000227175311800852!GO:0043492;ATPase activity, coupled to movement of substances;0.000239928716798667!GO:0005885;Arp2/3 protein complex;0.000247981636184174!GO:0043069;negative regulation of programmed cell death;0.000255509297294683!GO:0006839;mitochondrial transport;0.000273378955723683!GO:0006270;DNA replication initiation;0.000275382363952429!GO:0005684;U2-dependent spliceosome;0.000280711047674804!GO:0042626;ATPase activity, coupled to transmembrane movement of substances;0.000287776329039691!GO:0000079;regulation of cyclin-dependent protein kinase activity;0.000290227926032792!GO:0065009;regulation of a molecular function;0.000304265393084767!GO:0007052;mitotic spindle organization and biogenesis;0.000313069985763413!GO:0009124;nucleoside monophosphate biosynthetic process;0.000315099847823432!GO:0009123;nucleoside monophosphate metabolic process;0.000315099847823432!GO:0043066;negative regulation of apoptosis;0.000334664557104019!GO:0016281;eukaryotic translation initiation factor 4F complex;0.000357833061376201!GO:0019867;outer membrane;0.00036135272668587!GO:0043596;nuclear replication fork;0.00036135272668587!GO:0016820;hydrolase activity, acting on acid anhydrides, catalyzing transmembrane movement of substances;0.00037568354942515!GO:0005758;mitochondrial intermembrane space;0.000393721511170246!GO:0033178;proton-transporting two-sector ATPase complex, catalytic domain;0.000396926279972381!GO:0030384;phosphoinositide metabolic process;0.000402228526890595!GO:0031968;organelle outer membrane;0.000402228526890595!GO:0044262;cellular carbohydrate metabolic process;0.000411638197516511!GO:0006417;regulation of translation;0.000413361807947257!GO:0046489;phosphoinositide biosynthetic process;0.000424606438515827!GO:0005852;eukaryotic translation initiation factor 3 complex;0.000457786324205946!GO:0007249;I-kappaB kinase/NF-kappaB cascade;0.000459449340968223!GO:0031072;heat shock protein binding;0.000462425758806829!GO:0005770;late endosome;0.000483898558362503!GO:0043122;regulation of I-kappaB kinase/NF-kappaB cascade;0.000490492612538899!GO:0000059;protein import into nucleus, docking;0.00049898446503151!GO:0016563;transcription activator activity;0.000508213828979092!GO:0009451;RNA modification;0.000526902086982939!GO:0045261;proton-transporting ATP synthase complex, catalytic core F(1);0.000529421595220995!GO:0045786;negative regulation of progression through cell cycle;0.000536385816732339!GO:0000228;nuclear chromosome;0.000568893555943838!GO:0016251;general RNA polymerase II transcription factor activity;0.000574793332923113!GO:0006402;mRNA catabolic process;0.000607428741329556!GO:0051427;hormone receptor binding;0.000617996768871713!GO:0006352;transcription initiation;0.000624850390319458!GO:0043123;positive regulation of I-kappaB kinase/NF-kappaB cascade;0.000632074608406529!GO:0000287;magnesium ion binding;0.000644103375160827!GO:0044440;endosomal part;0.000694936562584981!GO:0010008;endosome membrane;0.000694936562584981!GO:0005637;nuclear inner membrane;0.000710060418536598!GO:0016891;endoribonuclease activity, producing 5'-phosphomonoesters;0.000766205171750946!GO:0045263;proton-transporting ATP synthase complex, coupling factor F(o);0.00077065418300584!GO:0033177;proton-transporting two-sector ATPase complex, proton-transporting domain;0.00077065418300584!GO:0007006;mitochondrial membrane organization and biogenesis;0.000818777388248384!GO:0006650;glycerophospholipid metabolic process;0.000853377854655598!GO:0009161;ribonucleoside monophosphate metabolic process;0.00085824742140951!GO:0009156;ribonucleoside monophosphate biosynthetic process;0.00085824742140951!GO:0048523;negative regulation of cellular process;0.000908836832656497!GO:0005741;mitochondrial outer membrane;0.000910641431410119!GO:0050662;coenzyme binding;0.0009187544518963!GO:0004540;ribonuclease activity;0.000970598483838596!GO:0016679;oxidoreductase activity, acting on diphenols and related substances as donors;0.000992610853199539!GO:0016681;oxidoreductase activity, acting on diphenols and related substances as donors, cytochrome as acceptor;0.000992610853199539!GO:0008121;ubiquinol-cytochrome-c reductase activity;0.000992610853199539!GO:0051539;4 iron, 4 sulfur cluster binding;0.000993207273598978!GO:0016893;endonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters;0.00102791995563815!GO:0051540;metal cluster binding;0.00104984523472523!GO:0051536;iron-sulfur cluster binding;0.00104984523472523!GO:0006284;base-excision repair;0.00110354696375436!GO:0000922;spindle pole;0.00118186676880755!GO:0035257;nuclear hormone receptor binding;0.00120721922146279!GO:0022890;inorganic cation transmembrane transporter activity;0.0013406631764374!GO:0031326;regulation of cellular biosynthetic process;0.00136652434186019!GO:0015631;tubulin binding;0.00138304663741939!GO:0031970;organelle envelope lumen;0.00138304663741939!GO:0000725;recombinational repair;0.00148654941746095!GO:0000724;double-strand break repair via homologous recombination;0.00148654941746095!GO:0005665;DNA-directed RNA polymerase II, core complex;0.0015429726570963!GO:0009308;amine metabolic process;0.0015555385772531!GO:0006807;nitrogen compound metabolic process;0.00156685406619792!GO:0043601;nuclear replisome;0.00156996266765891!GO:0030894;replisome;0.00156996266765891!GO:0009116;nucleoside metabolic process;0.00158117737239055!GO:0003711;transcription elongation regulator activity;0.00158509818462053!GO:0008610;lipid biosynthetic process;0.0017508471417667!GO:0000070;mitotic sister chromatid segregation;0.00178953776773702!GO:0016627;oxidoreductase activity, acting on the CH-CH group of donors;0.00197586342469568!GO:0000819;sister chromatid segregation;0.00198313301356933!GO:0031570;DNA integrity checkpoint;0.00203440493343809!GO:0005838;proteasome regulatory particle (sensu Eukaryota);0.00206809064155137!GO:0048500;signal recognition particle;0.00206814929391214!GO:0016272;prefoldin complex;0.0021031821698293!GO:0008312;7S RNA binding;0.00215292995713631!GO:0016796;exonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters;0.00218976916148393!GO:0000178;exosome (RNase complex);0.00228933021404081!GO:0006506;GPI anchor biosynthetic process;0.00229132094255124!GO:0006497;protein amino acid lipidation;0.00233033380323075!GO:0003755;peptidyl-prolyl cis-trans isomerase activity;0.002339656811113!GO:0005048;signal sequence binding;0.00258109071940961!GO:0016859;cis-trans isomerase activity;0.00263992764600863!GO:0008757;S-adenosylmethionine-dependent methyltransferase activity;0.00266082998903244!GO:0003725;double-stranded RNA binding;0.00271167292203748!GO:0000339;RNA cap binding;0.00280858525769163!GO:0051087;chaperone binding;0.00285848019215405!GO:0031124;mRNA 3'-end processing;0.00300806043329575!GO:0000096;sulfur amino acid metabolic process;0.00303477707316248!GO:0005525;GTP binding;0.00304043830787005!GO:0046467;membrane lipid biosynthetic process;0.00307610886813674!GO:0005798;Golgi-associated vesicle;0.00313097660783249!GO:0031252;leading edge;0.00316787971687755!GO:0008408;3'-5' exonuclease activity;0.00326457708659968!GO:0000184;mRNA catabolic process, nonsense-mediated decay;0.00329638908944431!GO:0009303;rRNA transcription;0.00338637804375917!GO:0008139;nuclear localization sequence binding;0.00339476708811673!GO:0030867;rough endoplasmic reticulum membrane;0.00343438834394891!GO:0006595;polyamine metabolic process;0.00347876276965647!GO:0006406;mRNA export from nucleus;0.00348679919508681!GO:0006144;purine base metabolic process;0.0034996129743312!GO:0006505;GPI anchor metabolic process;0.0035270877610937!GO:0006611;protein export from nucleus;0.00355017123769862!GO:0009127;purine nucleoside monophosphate biosynthetic process;0.00362219590975167!GO:0009167;purine ribonucleoside monophosphate metabolic process;0.00362219590975167!GO:0009126;purine nucleoside monophosphate metabolic process;0.00362219590975167!GO:0009168;purine ribonucleoside monophosphate biosynthetic process;0.00362219590975167!GO:0000226;microtubule cytoskeleton organization and biogenesis;0.00363754314013206!GO:0005669;transcription factor TFIID complex;0.00382806439379793!GO:0047485;protein N-terminus binding;0.0040096425666122!GO:0006275;regulation of DNA replication;0.00423530764815462!GO:0008180;signalosome;0.00427895790112369!GO:0006289;nucleotide-excision repair;0.00429381791042708!GO:0033116;ER-Golgi intermediate compartment membrane;0.00433321528145224!GO:0003887;DNA-directed DNA polymerase activity;0.00433590270692478!GO:0032200;telomere organization and biogenesis;0.00443720177700268!GO:0000723;telomere maintenance;0.00443720177700268!GO:0016676;oxidoreductase activity, acting on heme group of donors, oxygen as acceptor;0.00456003421821497!GO:0015002;heme-copper terminal oxidase activity;0.00456003421821497!GO:0016675;oxidoreductase activity, acting on heme group of donors;0.00456003421821497!GO:0004129;cytochrome-c oxidase activity;0.00456003421821497!GO:0008632;apoptotic program;0.00458587047638778!GO:0019843;rRNA binding;0.00469064982985753!GO:0043284;biopolymer biosynthetic process;0.00475816618144248!GO:0005786;signal recognition particle, endoplasmic reticulum targeting;0.00494706597336092!GO:0051053;negative regulation of DNA metabolic process;0.00500043115222496!GO:0006614;SRP-dependent cotranslational protein targeting to membrane;0.00500043115222496!GO:0045047;protein targeting to ER;0.00500043115222496!GO:0006612;protein targeting to membrane;0.00500467889540249!GO:0006778;porphyrin metabolic process;0.00511742726794777!GO:0033013;tetrapyrrole metabolic process;0.00511742726794777!GO:0009889;regulation of biosynthetic process;0.00514739929471832!GO:0005769;early endosome;0.00545660427314998!GO:0000726;non-recombinational repair;0.00560337024537343!GO:0016765;transferase activity, transferring alkyl or aryl (other than methyl) groups;0.00585092973578114!GO:0044431;Golgi apparatus part;0.00593873515172149!GO:0006118;electron transport;0.00597656258856962!GO:0048037;cofactor binding;0.00624246835669194!GO:0000910;cytokinesis;0.00624246835669194!GO:0004532;exoribonuclease activity;0.00632309751956911!GO:0016896;exoribonuclease activity, producing 5'-phosphomonoesters;0.00632309751956911!GO:0048519;negative regulation of biological process;0.00639879178199108!GO:0000781;chromosome, telomeric region;0.00653509235865511!GO:0030658;transport vesicle membrane;0.00657565968137874!GO:0042393;histone binding;0.00673349366743287!GO:0006400;tRNA modification;0.00673349366743287!GO:0031123;RNA 3'-end processing;0.0068722428118534!GO:0044454;nuclear chromosome part;0.00689641099921819!GO:0006779;porphyrin biosynthetic process;0.00693711685269677!GO:0033014;tetrapyrrole biosynthetic process;0.00693711685269677!GO:0004261;cathepsin G activity;0.00696770014021724!GO:0000793;condensed chromosome;0.00700279042993979!GO:0043065;positive regulation of apoptosis;0.00702208532943796!GO:0050790;regulation of catalytic activity;0.00719425939553022!GO:0006367;transcription initiation from RNA polymerase II promoter;0.00727313488104672!GO:0042158;lipoprotein biosynthetic process;0.00737900304689006!GO:0007007;inner mitochondrial membrane organization and biogenesis;0.007523749497389!GO:0051252;regulation of RNA metabolic process;0.00755695458126222!GO:0031988;membrane-bound vesicle;0.00760779483398723!GO:0000077;DNA damage checkpoint;0.00761281707272442!GO:0003924;GTPase activity;0.00792860168053496!GO:0005774;vacuolar membrane;0.00806295868822027!GO:0007017;microtubule-based process;0.00808733670516069!GO:0005832;chaperonin-containing T-complex;0.00819970744353751!GO:0016126;sterol biosynthetic process;0.00829982217362192!GO:0006338;chromatin remodeling;0.00833131999000127!GO:0004448;isocitrate dehydrogenase activity;0.00847802850589389!GO:0006378;mRNA polyadenylation;0.00865798878890652!GO:0008276;protein methyltransferase activity;0.00867359524070951!GO:0007021;tubulin folding;0.00876309876922517!GO:0005876;spindle microtubule;0.00876309876922517!GO:0008652;amino acid biosynthetic process;0.00888835929264208!GO:0004003;ATP-dependent DNA helicase activity;0.00896297986326825!GO:0048487;beta-tubulin binding;0.00900916721925225!GO:0003746;translation elongation factor activity;0.00912077796301432!GO:0043068;positive regulation of programmed cell death;0.00919353359058016!GO:0006695;cholesterol biosynthetic process;0.00971607831157565!GO:0005996;monosaccharide metabolic process;0.00979632942798493!GO:0031324;negative regulation of cellular metabolic process;0.00998638756653217!GO:0016408;C-acyltransferase activity;0.0101121020893351!GO:0043022;ribosome binding;0.0103535978771895!GO:0051287;NAD binding;0.010569774612424!GO:0035258;steroid hormone receptor binding;0.0106091911436301!GO:0019318;hexose metabolic process;0.0106506452309261!GO:0016862;intramolecular oxidoreductase activity, interconverting keto- and enol-groups;0.0106688156535183!GO:0042802;identical protein binding;0.0108339583805639!GO:0030663;COPI coated vesicle membrane;0.0108743544529288!GO:0030126;COPI vesicle coat;0.0108743544529288!GO:0006740;NADPH regeneration;0.0109171426470686!GO:0006098;pentose-phosphate shunt;0.0109171426470686!GO:0006007;glucose catabolic process;0.0110052255558824!GO:0030660;Golgi-associated vesicle membrane;0.0114809828203252!GO:0031982;vesicle;0.0117228902303014!GO:0005663;DNA replication factor C complex;0.0120865004230084!GO:0046112;nucleobase biosynthetic process;0.0123068740756621!GO:0000792;heterochromatin;0.0130964616981059!GO:0003857;3-hydroxyacyl-CoA dehydrogenase activity;0.0132881443202408!GO:0035267;NuA4 histone acetyltransferase complex;0.0133196480967397!GO:0016584;nucleosome positioning;0.0133196480967397!GO:0005874;microtubule;0.0135977468326749!GO:0004523;ribonuclease H activity;0.0136197161287343!GO:0043189;H4/H2A histone acetyltransferase complex;0.0136619197546534!GO:0042168;heme metabolic process;0.013705869495144!GO:0000139;Golgi membrane;0.0137356132193304!GO:0015036;disulfide oxidoreductase activity;0.0138609194430401!GO:0004519;endonuclease activity;0.0141961801209929!GO:0007040;lysosome organization and biogenesis;0.0142396122582078!GO:0016023;cytoplasmic membrane-bound vesicle;0.0144431544181344!GO:0000152;nuclear ubiquitin ligase complex;0.0145120404864617!GO:0007243;protein kinase cascade;0.0146640732200989!GO:0032259;methylation;0.0148288710606613!GO:0043161;proteasomal ubiquitin-dependent protein catabolic process;0.0148959521897214!GO:0016667;oxidoreductase activity, acting on sulfur group of donors;0.0149558357707647!GO:0032561;guanyl ribonucleotide binding;0.0149558357707647!GO:0019001;guanyl nucleotide binding;0.0149558357707647!GO:0030176;integral to endoplasmic reticulum membrane;0.0152625446118461!GO:0042719;mitochondrial intermembrane space protein transporter complex;0.0153300194513243!GO:0045039;protein import into mitochondrial inner membrane;0.0153300194513243!GO:0042770;DNA damage response, signal transduction;0.0153606666490717!GO:0044437;vacuolar part;0.0155542075275032!GO:0008017;microtubule binding;0.0156381697281245!GO:0007033;vacuole organization and biogenesis;0.0156849150775292!GO:0005732;small nucleolar ribonucleoprotein complex;0.0161729315065851!GO:0030521;androgen receptor signaling pathway;0.0163479659080505!GO:0004674;protein serine/threonine kinase activity;0.0163740456786695!GO:0006607;NLS-bearing substrate import into nucleus;0.0164449212882744!GO:0007034;vacuolar transport;0.016527510002827!GO:0045934;negative regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process;0.0167116653798243!GO:0005765;lysosomal membrane;0.0171976373901029!GO:0001726;ruffle;0.0174094843100905!GO:0006376;mRNA splice site selection;0.017491692810131!GO:0000389;nuclear mRNA 3'-splice site recognition;0.017491692810131!GO:0006733;oxidoreduction coenzyme metabolic process;0.0180147305068838!GO:0051656;establishment of organelle localization;0.0180147305068838!GO:0032940;secretion by cell;0.0180973906160407!GO:0051320;S phase;0.0182259814226845!GO:0006783;heme biosynthetic process;0.0182651065764781!GO:0000175;3'-5'-exoribonuclease activity;0.0184198749571457!GO:0016860;intramolecular oxidoreductase activity;0.0184198749571457!GO:0051789;response to protein stimulus;0.0184198749571457!GO:0006986;response to unfolded protein;0.0184198749571457!GO:0033367;protein localization in mast cell secretory granule;0.0184198749571457!GO:0033365;protein localization in organelle;0.0184198749571457!GO:0033371;T cell secretory granule organization and biogenesis;0.0184198749571457!GO:0033373;maintenance of protease localization in mast cell secretory granule;0.0184198749571457!GO:0033375;protease localization in T cell secretory granule;0.0184198749571457!GO:0042629;mast cell granule;0.0184198749571457!GO:0033377;maintenance of protein localization in T cell secretory granule;0.0184198749571457!GO:0033364;mast cell secretory granule organization and biogenesis;0.0184198749571457!GO:0033380;granzyme B localization in T cell secretory granule;0.0184198749571457!GO:0033379;maintenance of protease localization in T cell secretory granule;0.0184198749571457!GO:0033370;maintenance of protein localization in mast cell secretory granule;0.0184198749571457!GO:0033368;protease localization in mast cell secretory granule;0.0184198749571457!GO:0033366;protein localization in secretory granule;0.0184198749571457!GO:0033382;maintenance of granzyme B localization in T cell secretory granule;0.0184198749571457!GO:0033374;protein localization in T cell secretory granule;0.0184198749571457!GO:0031577;spindle checkpoint;0.0184598430109439!GO:0008156;negative regulation of DNA replication;0.0185628632412991!GO:0006213;pyrimidine nucleoside metabolic process;0.0193382914855719!GO:0005975;carbohydrate metabolic process;0.0194505539598924!GO:0046822;regulation of nucleocytoplasmic transport;0.0202648538510234!GO:0006672;ceramide metabolic process;0.0202669898376292!GO:0046365;monosaccharide catabolic process;0.0208634085801672!GO:0030508;thiol-disulfide exchange intermediate activity;0.0211461488979223!GO:0007050;cell cycle arrest;0.0219198760265804!GO:0000123;histone acetyltransferase complex;0.0219771969844354!GO:0045045;secretory pathway;0.0225170267688881!GO:0016197;endosome transport;0.0229198165535677!GO:0008250;oligosaccharyl transferase complex;0.0230765961026424!GO:0008047;enzyme activator activity;0.0234872261951274!GO:0043414;biopolymer methylation;0.0235885599746494!GO:0006891;intra-Golgi vesicle-mediated transport;0.0238651547531046!GO:0004576;oligosaccharyl transferase activity;0.0240586074374503!GO:0009119;ribonucleoside metabolic process;0.0244760555129492!GO:0044438;microbody part;0.024635213570043!GO:0044439;peroxisomal part;0.024635213570043!GO:0004659;prenyltransferase activity;0.0252091125657625!GO:0051098;regulation of binding;0.0262495165520311!GO:0006643;membrane lipid metabolic process;0.0263415644053425!GO:0000307;cyclin-dependent protein kinase holoenzyme complex;0.0264330673073279!GO:0009081;branched chain family amino acid metabolic process;0.0265822018432558!GO:0006220;pyrimidine nucleotide metabolic process;0.0265822018432558!GO:0032981;mitochondrial respiratory chain complex I assembly;0.0265822018432558!GO:0010257;NADH dehydrogenase complex assembly;0.0265822018432558!GO:0033108;mitochondrial respiratory chain complex assembly;0.0265822018432558!GO:0030137;COPI-coated vesicle;0.0267579228363224!GO:0031410;cytoplasmic vesicle;0.0267579228363224!GO:0016564;transcription repressor activity;0.0269519666637503!GO:0004526;ribonuclease P activity;0.0275042835595535!GO:0009892;negative regulation of metabolic process;0.0277899570744704!GO:0046164;alcohol catabolic process;0.0277899570744704!GO:0030118;clathrin coat;0.0278157814655888!GO:0032039;integrator complex;0.0283168926969332!GO:0001522;pseudouridine synthesis;0.0284310284410245!GO:0006356;regulation of transcription from RNA polymerase I promoter;0.0286136359857813!GO:0005850;eukaryotic translation initiation factor 2 complex;0.0292090200429286!GO:0009066;aspartate family amino acid metabolic process;0.0300949487723851!GO:0006730;one-carbon compound metabolic process;0.0310881886071786!GO:0043631;RNA polyadenylation;0.0312178568445283!GO:0004579;dolichyl-diphosphooligosaccharide-protein glycotransferase activity;0.0313266320645844!GO:0019320;hexose catabolic process;0.0318074898349798!GO:0004185;serine carboxypeptidase activity;0.0318892150408087!GO:0005869;dynactin complex;0.0320429007826495!GO:0009615;response to virus;0.0322664246997278!GO:0005658;alpha DNA polymerase:primase complex;0.0323305790407799!GO:0006635;fatty acid beta-oxidation;0.032591423695244!GO:0031903;microbody membrane;0.0335641407444709!GO:0005778;peroxisomal membrane;0.0335641407444709!GO:0006516;glycoprotein catabolic process;0.0339493979808707!GO:0002763;positive regulation of myeloid leukocyte differentiation;0.0340491513398632!GO:0032984;macromolecular complex disassembly;0.0342772763128748!GO:0003756;protein disulfide isomerase activity;0.0348779878206053!GO:0016864;intramolecular oxidoreductase activity, transposing S-S bonds;0.0348779878206053!GO:0030134;ER to Golgi transport vesicle;0.0350106808898863!GO:0001832;blastocyst growth;0.0350493847442508!GO:0008144;drug binding;0.0360443571732405!GO:0019206;nucleoside kinase activity;0.0362015734134519!GO:0006767;water-soluble vitamin metabolic process;0.03626327742884!GO:0008538;proteasome activator activity;0.0366646157782602!GO:0005784;translocon complex;0.0366646157782602!GO:0000097;sulfur amino acid biosynthetic process;0.0367558682792898!GO:0048471;perinuclear region of cytoplasm;0.0380475725238583!GO:0009262;deoxyribonucleotide metabolic process;0.0385899982709542!GO:0008287;protein serine/threonine phosphatase complex;0.0389252773091236!GO:0030518;steroid hormone receptor signaling pathway;0.03911080120166!GO:0031371;ubiquitin conjugating enzyme complex;0.0394988648426857!GO:0006303;double-strand break repair via nonhomologous end joining;0.0396954919790229!GO:0009067;aspartate family amino acid biosynthetic process;0.0397338122247129!GO:0033170;DNA-protein loading ATPase activity;0.0416730051922937!GO:0003689;DNA clamp loader activity;0.0416730051922937!GO:0005689;U12-dependent spliceosome;0.041745996378269!GO:0003923;GPI-anchor transamidase activity;0.0418255293891116!GO:0016255;attachment of GPI anchor to protein;0.0418255293891116!GO:0042765;GPI-anchor transamidase complex;0.0418255293891116!GO:0007094;mitotic cell cycle spindle assembly checkpoint;0.0420044556462232!GO:0048522;positive regulation of cellular process;0.042469491879316!GO:0008536;Ran GTPase binding;0.0426124890310133!GO:0042026;protein refolding;0.0427353396541727!GO:0004815;aspartate-tRNA ligase activity;0.0427353396541727!GO:0006422;aspartyl-tRNA aminoacylation;0.0427353396541727!GO:0030127;COPII vesicle coat;0.0427353396541727!GO:0012507;ER to Golgi transport vesicle membrane;0.0427353396541727!GO:0022411;cellular component disassembly;0.0427504300267179!GO:0051881;regulation of mitochondrial membrane potential;0.0427586405772896!GO:0006917;induction of apoptosis;0.0433815062974633!GO:0050178;phenylpyruvate tautomerase activity;0.0434649630037165!GO:0003893;epsilon DNA polymerase activity;0.043499378966778!GO:0003709;RNA polymerase III transcription factor activity;0.0437463135634157!GO:0006379;mRNA cleavage;0.0439975331558662!GO:0051059;NF-kappaB binding;0.0440561578027369!GO:0031647;regulation of protein stability;0.0440561578027369!GO:0051920;peroxiredoxin activity;0.0441263932250312!GO:0008097;5S rRNA binding;0.045077117995127!GO:0006555;methionine metabolic process;0.0457061642255687!GO:0007004;telomere maintenance via telomerase;0.0461538859438927!GO:0046479;glycosphingolipid catabolic process;0.0464777782622187!GO:0016279;protein-lysine N-methyltransferase activity;0.0467202161980256!GO:0018024;histone-lysine N-methyltransferase activity;0.0467202161980256!GO:0016278;lysine N-methyltransferase activity;0.0467202161980256!GO:0019901;protein kinase binding;0.0472419950967863!GO:0009396;folic acid and derivative biosynthetic process;0.0477747251860253!GO:0018196;peptidyl-asparagine modification;0.0477747251860253!GO:0018279;protein amino acid N-linked glycosylation via asparagine;0.0477747251860253!GO:0006596;polyamine biosynthetic process;0.047894406284977!GO:0006644;phospholipid metabolic process;0.0479145609460189!GO:0022415;viral reproductive process;0.0483427358888484!GO:0030132;clathrin coat of coated pit;0.0483525974807309!GO:0003988;acetyl-CoA C-acyltransferase activity;0.0483525974807309!GO:0016407;acetyltransferase activity;0.0484078522567276!GO:0004536;deoxyribonuclease activity;0.0486006318933923!GO:0006301;postreplication repair;0.0488218079289526!GO:0042054;histone methyltransferase activity;0.048838965751141!GO:0003985;acetyl-CoA C-acetyltransferase activity;0.0492401027078558!GO:0030174;regulation of DNA replication initiation;0.0492849979395009!GO:0051090;regulation of transcription factor activity;0.0492955057363943!GO:0032404;mismatch repair complex binding;0.0493962542716767!GO:0051338;regulation of transferase activity;0.0497169952418711!GO:0008320;protein transmembrane transporter activity;0.0499476962124649 | |||
|sample_id=10834 | |||
|sample_note= | |||
|sample_sex=male | |||
|sample_species=Human (Homo sapiens) | |||
|sample_strain= | |||
|sample_tissue=blood | |||
|top_motifs=MYB:2.12193472649;E2F1..5:1.96508115438;ARNT_ARNT2_BHLHB2_MAX_MYC_USF1:1.72351301129;NKX2-2,8:1.58475360192;RXR{A,B,G}_{NR1H2,PPAR}dimers:1.54325434651;SPIB:1.15692297003;ELK1,4_GABP{A,B1}:1.06325320151;YY1:1.04702702955;ELF1,2,4:1.03623542647;SPI1:0.93329196574;FOXA2:0.837737617839;NRF1:0.813004664377;NR5A1,2:0.733981495862;ETS1,2:0.728710933839;DMAP1_NCOR{1,2}_SMARC:0.727920221489;NR6A1:0.712671274516;GATA4:0.625674746471;NANOG{mouse}:0.62479530329;ZNF143:0.617941184437;PAX3,7:0.612197130094;RUNX1..3:0.60936935402;POU5F1:0.575670559776;IKZF2:0.569033722877;NFY{A,B,C}:0.56271226132;FOXP3:0.534010135185;TEF:0.519347723217;ESRRA:0.518625458309;TFDP1:0.508292351407;NKX3-2:0.493892744442;CEBPA,B_DDIT3:0.493386552529;CRX:0.482933439031;KLF4:0.470256954899;BREu{core}:0.456126067261;AIRE:0.4297550484;bHLH_family:0.427028350364;GATA6:0.407542898388;CUX2:0.39490117495;HOX{A5,B5}:0.37877684418;FOXD3:0.363824389373;FOXQ1:0.348293601132;HAND1,2:0.340246803081;GCM1,2:0.332570823988;ARID5B:0.309089207413;RXRA_VDR{dimer}:0.292122258625;PITX1..3:0.235727867039;POU2F1..3:0.226123155581;ZNF238:0.225878919531;NKX3-1:0.199323335452;HNF4A_NR2F1,2:0.190733854185;ZBTB16:0.177871439317;OCT4_SOX2{dimer}:0.173597767616;PAX8:0.162380885586;NANOG:0.155568428843;NFIL3:0.141228006825;EN1,2:0.129165832893;GFI1:0.110863384943;HOX{A6,A7,B6,B7}:0.10177459471;SREBF1,2:0.0695103995582;PRRX1,2:0.0665019800482;NKX6-1,2:0.062889124139;HLF:0.0439098281534;HBP1_HMGB_SSRP1_UBTF:0.0233124144459;VSX1,2:0.0152408850658;PAX5:-0.00560079314208;HOX{A4,D4}:-0.0649046641502;NKX2-3_NKX2-5:-0.0658031341271;REST:-0.0937088341895;HES1:-0.107447886291;IKZF1:-0.137701452483;ALX1:-0.140283592704;PAX2:-0.141082773441;POU1F1:-0.151639532662;MYOD1:-0.166112606825;AR:-0.172422511288;RFX2..5_RFXANK_RFXAP:-0.185973451892;AHR_ARNT_ARNT2:-0.18599235354;SOX{8,9,10}:-0.206319434778;PRDM1:-0.21519425957;FOX{I1,J2}:-0.219777192888;NFKB1_REL_RELA:-0.226156470494;UFEwm:-0.2274076757;CDX1,2,4:-0.227857826464;ATF5_CREB3:-0.229038112231;T:-0.236856573381;PBX1:-0.237139221072;EP300:-0.246725632103;FOXM1:-0.24785020697;POU6F1:-0.258128263212;PPARG:-0.270000760338;MYBL2:-0.273620206826;MTF1:-0.273871244055;IRF7:-0.2738971037;FOXP1:-0.290248694147;IRF1,2:-0.291791455389;TOPORS:-0.30613402942;HSF1,2:-0.309272757614;ONECUT1,2:-0.311625337211;HNF1A:-0.31294941085;GZF1:-0.335948620778;NFE2:-0.339703138322;MYFfamily:-0.348009806627;NR1H4:-0.353625366743;FOSL2:-0.359338978966;DBP:-0.369651065885;ZEB1:-0.371952889492;SOX17:-0.372555195831;TLX2:-0.375595332898;RORA:-0.377860339666;HMX1:-0.379298473878;SNAI1..3:-0.400385567058;NKX2-1,4:-0.410648012572;ZNF384:-0.428132757626;STAT5{A,B}:-0.433690632679;RBPJ:-0.456850954879;HIF1A:-0.476545455475;TGIF1:-0.481838979176;POU3F1..4:-0.500358648944;NFE2L2:-0.504260979012;XBP1:-0.511713378386;NFE2L1:-0.513280959065;SPZ1:-0.515223893538;MEF2{A,B,C,D}:-0.518675197964;FOX{F1,F2,J1}:-0.521678396194;CREB1:-0.525257864839;FOS_FOS{B,L1}_JUN{B,D}:-0.526701235654;RREB1:-0.584297523375;BACH2:-0.587435300386;PAX6:-0.59493288064;HOXA9_MEIS1:-0.60432328866;LEF1_TCF7_TCF7L1,2:-0.625948231049;ZNF423:-0.628800738992;PDX1:-0.656576792822;RXR{A,B,G}:-0.657559294394;MZF1:-0.663133488701;ESR1:-0.672811342439;ATF4:-0.702169926226;FOXN1:-0.704863255701;EVI1:-0.72432837947;PAX4:-0.736491033641;ALX4:-0.75851729288;NHLH1,2:-0.801412434895;SRF:-0.843251926784;GTF2A1,2:-0.850169114423;ZBTB6:-0.857485639481;LMO2:-0.860197365272;LHX3,4:-0.899137257785;MAFB:-0.904887603027;TAL1_TCF{3,4,12}:-0.916468916977;ZNF148:-0.919787712752;EBF1:-0.922680173021;FOXO1,3,4:-0.93337063271;BPTF:-0.93382649665;TP53:-0.970104945236;HMGA1,2:-0.976410971308;RFX1:-0.98020700609;TFAP2{A,C}:-0.982824664272;ZFP161:-0.984051931461;ADNP_IRX_SIX_ZHX:-0.994064543733;FOXL1:-1.0304703059;CDC5L:-1.05128700985;SOX5:-1.0532960674;GTF2I:-1.05818570199;ZIC1..3:-1.05999748215;MTE{core}:-1.09854689755;NFIX:-1.1244486796;NR3C1:-1.14988747854;TLX1..3_NFIC{dimer}:-1.18101083228;TFCP2:-1.19971643003;PAX1,9:-1.21520081612;SMAD1..7,9:-1.22841482146;STAT2,4,6:-1.23581093606;TFAP4:-1.2425827708;MED-1{core}:-1.30604743678;TEAD1:-1.31063590068;SP1:-1.32439622133;TBX4,5:-1.34141495552;NFATC1..3:-1.35167589785;ATF2:-1.35795676084;GLI1..3:-1.36161695242;HIC1:-1.39024483808;TBP:-1.41001430299;SOX2:-1.45514277181;STAT1,3:-1.48589770496;ATF6:-1.51752521759;GFI1B:-1.52741655813;PATZ1:-1.57552798655;TFAP2B:-1.58496211421;FOX{D1,D2}:-1.62694136197;JUN:-1.72460706571;XCPE1{core}:-1.76266522846;EGR1..3:-1.83691570777;MAZ:-1.89078906967 | |||
|xref= | |||
|zenbu_report=https://fantom.gsc.riken.jp/zenbu/reports/#miRNA_expression_atlas_human;search_select_hide=table111:FF:10834-111D6;search_select_hide=table117:FF:10834-111D6 | |||
}} | }} |
Latest revision as of 15:08, 3 June 2020
Name: | acute myeloid leukemia (FAB M5) cell line:U-937 DE-4 |
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Species: | Human (Homo sapiens) |
Library ID: | CNhs13058 |
Sample type: | cell lines |
Genomic View: | UCSC |
RefEX: | Specific genes |
CAGEd-oPOSSUM: | link |
ZENBU report : | link |
Additional information | ||||||||||||||||||||||||||||
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Sample information
RNA information
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CAGE Accession numbers | ||||||||||||||||||||||||||||||||||||||||||||||
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Download raw sequence, BAM & CTSS | ||||||||||||||
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Relative expression to median (log10)
Transcription factors with enriched expression in this sampleRanked list of transcription factor promoter expression in this sample relative to the median expression in the FANTOM5 collection is shown. Value is log10 transformed.
Co-expression clusters with enriched expression in this sampleRanked list of co-expression cluster expression in this sample relative to the median expression in the FANTOM5 collection is shown. Value is log10 transformed. <br>Analyst:NA <br><br>link to dataset.<br>data
Repeat families with enriched expression in this sample<b>Summary:</b>Ranked list of repeat family expression in this sample relative tothe median expression in the FANTOM5 collection is shown. Value is log10transformed.<br><b>Analyst:</b>NA<br><br>link to dataset.<br>data
TFBS(DNA)motifs over-represented in proximal region of promoters active in this sample
JASPAR motifs<b>Summary:</b>Association of JASPAR motif to the promoter expression in thissample. Pearson's correlation between the number of TFBSs estimated byusing the position-weight matrix for each promoter and its expression isexpressed as Z-score by taking the ones based on random position-weightmatrix, and the tail probability of the normal distribution correspondingto the Z-score is taken as the resulting P-value. Lower P-value indicatesmore (non-random) association of the motif to promoter expression<br><b>Analyst:</b> Michiel de Hoon <br><br><br>link to dataset.<br>data
library id: CNhs13058
FANTOM5 phase1 novel unique motifs<b>Summary:</b>Association of the 169 novel and unique motifs discovered in FANTOM5 phase1 in this sample. Among the de-novo motifs discovered by DMF, HOMER,ChIPMunk, and ScanAll, only novel motifs are selected after comparison with known motif sets, and their clustering based on MACRO-APE resulted in169 novel and unique motifs. Their association to the promoter expression is evaluated in the same way to the JASPAR motif above<br><b>Analyst:</b> Michiel de Hoon <br><br><br>link to dataset.<br>data
library id: CNhs13058
Novel motif | Logo | P-value |
---|---|---|
1 | 1 | 0.00947 |
10 | 10 | 0.00827 |
100 | 100 | 0.312 |
101 | 101 | 0.262 |
102 | 102 | 0.347 |
103 | 103 | 0.372 |
104 | 104 | 0.943 |
105 | 105 | 0.27 |
106 | 106 | 0.579 |
107 | 107 | 0.366 |
108 | 108 | 0.982 |
109 | 109 | 0.0485 |
11 | 11 | 0.0493 |
110 | 110 | 0.0643 |
111 | 111 | 0.0095 |
112 | 112 | 0.179 |
113 | 113 | 0.556 |
114 | 114 | 0.0683 |
115 | 115 | 0.595 |
116 | 116 | 0.279 |
117 | 117 | 0.0119 |
118 | 118 | 0.0883 |
119 | 119 | 0.675 |
12 | 12 | 0.994 |
120 | 120 | 0.233 |
121 | 121 | 0.674 |
122 | 122 | 0.994 |
123 | 123 | 0.162 |
124 | 124 | 0.0625 |
125 | 125 | 0.0169 |
126 | 126 | 0.0873 |
127 | 127 | 0.0713 |
128 | 128 | 0.511 |
129 | 129 | 0.555 |
13 | 13 | 0.0222 |
130 | 130 | 0.75 |
131 | 131 | 0.259 |
132 | 132 | 0.45 |
133 | 133 | 0.899 |
134 | 134 | 0.844 |
135 | 135 | 0.37 |
136 | 136 | 0.214 |
137 | 137 | 0.126 |
138 | 138 | 0.449 |
139 | 139 | 0.398 |
14 | 14 | 0.975 |
140 | 140 | 0.0751 |
141 | 141 | 0.494 |
142 | 142 | 0.606 |
143 | 143 | 0.228 |
144 | 144 | 0.672 |
145 | 145 | 0.949 |
146 | 146 | 0.841 |
147 | 147 | 0.158 |
148 | 148 | 0.0691 |
149 | 149 | 0.539 |
15 | 15 | 0.0743 |
150 | 150 | 0.841 |
151 | 151 | 0.924 |
152 | 152 | 0.084 |
153 | 153 | 0.304 |
154 | 154 | 0.844 |
155 | 155 | 0.2 |
156 | 156 | 0.868 |
157 | 157 | 0.171 |
158 | 158 | 0.853 |
159 | 159 | 0.892 |
16 | 16 | 0.641 |
160 | 160 | 0.209 |
161 | 161 | 0.0377 |
162 | 162 | 0.834 |
163 | 163 | 0.389 |
164 | 164 | 0.0804 |
165 | 165 | 0.0789 |
166 | 166 | 0.256 |
167 | 167 | 0.25 |
168 | 168 | 0.733 |
169 | 169 | 0.228 |
17 | 17 | 0.712 |
18 | 18 | 0.304 |
19 | 19 | 0.486 |
2 | 2 | 0.726 |
20 | 20 | 0.744 |
21 | 21 | 0.0255 |
22 | 22 | 0.68 |
23 | 23 | 0.24 |
24 | 24 | 0.0227 |
25 | 25 | 0.153 |
26 | 26 | 0.0656 |
27 | 27 | 0.413 |
28 | 28 | 0.85 |
29 | 29 | 0.036 |
3 | 3 | 0.0634 |
30 | 30 | 0.2 |
31 | 31 | 0.634 |
32 | 32 | 0.621 |
33 | 33 | 0.422 |
34 | 34 | 0.887 |
35 | 35 | 0.248 |
36 | 36 | 0.0417 |
37 | 37 | 0.301 |
38 | 38 | 0.31 |
39 | 39 | 0.347 |
4 | 4 | 0.0957 |
40 | 40 | 0.167 |
41 | 41 | 0.336 |
42 | 42 | 0.209 |
43 | 43 | 0.498 |
44 | 44 | 0.0122 |
45 | 45 | 0.453 |
46 | 46 | 0.0941 |
47 | 47 | 0.0454 |
48 | 48 | 0.0255 |
49 | 49 | 0.284 |
5 | 5 | 0.575 |
50 | 50 | 0.904 |
51 | 51 | 0.885 |
52 | 52 | 0.154 |
53 | 53 | 0.738 |
54 | 54 | 0.895 |
55 | 55 | 0.634 |
56 | 56 | 0.81 |
57 | 57 | 0.0696 |
58 | 58 | 0.153 |
59 | 59 | 0.387 |
6 | 6 | 0.303 |
60 | 60 | 0.971 |
61 | 61 | 0.0366 |
62 | 62 | 0.0857 |
63 | 63 | 0.467 |
64 | 64 | 0.107 |
65 | 65 | 0.967 |
66 | 66 | 0.278 |
67 | 67 | 0.399 |
68 | 68 | 0.724 |
69 | 69 | 0.576 |
7 | 7 | 0.09 |
70 | 70 | 0.916 |
71 | 71 | 0.00831 |
72 | 72 | 0.718 |
73 | 73 | 0.586 |
74 | 74 | 0.282 |
75 | 75 | 0.00869 |
76 | 76 | 0.57 |
77 | 77 | 0.79 |
78 | 78 | 0.0305 |
79 | 79 | 0.829 |
8 | 8 | 0.0436 |
80 | 80 | 0.874 |
81 | 81 | 0.127 |
82 | 82 | 0.482 |
83 | 83 | 0.68 |
84 | 84 | 0.566 |
85 | 85 | 0.382 |
86 | 86 | 0.383 |
87 | 87 | 0.235 |
88 | 88 | 0.43 |
89 | 89 | 0.37 |
9 | 9 | 0.56 |
90 | 90 | 0.184 |
91 | 91 | 0.97 |
92 | 92 | 0.694 |
93 | 93 | 0.172 |
94 | 94 | 0.387 |
95 | 95 | 0.0756 |
96 | 96 | 0.554 |
97 | 97 | 0.304 |
98 | 98 | 0.304 |
99 | 99 | 0.368 |
de novo motifs identified by HOMER in promoters active in this sample<b>Summary:</b>The result of HOMER in this sample is shown.<br><b>Analyst:</b>NA <br>
library id: CNhs13058
FANTOM5 (FF) ontology
Direct parent terms
is_a relathionship
EFO:0002091 biological replicate
FF:0000210 human sample
FF:0101883 acute myeloid leukemia cell line sample
Ancestor terms (non development)<b>Summary:</b>Connected ontology terms with is_a, part_of or located_in relationship <br><b>Analyst:</b> Hideya Kawaji<br><br>link to source data<br>data
CL: Cell type
0000000 (cell), 0000000 (cell)
0000003 (native cell)
0000988 (hematopoietic cell)
0000548 (animal cell)
0000763 (myeloid cell)
0002371 (somatic cell)
0000255 (eukaryotic cell)
DOID: Disease
4 (disease)
0050686 (organ system cancer)
162 (cancer)
2531 (hematologic cancer)
14566 (disease of cellular proliferation)
0060083 (immune system cancer)
1240 (leukemia)
8692 (myeloid leukemia)
FF: FANTOM5
0000102 (sample by type)
0000003 (cell line sample)
0000210 (human sample)
0000101 (sample by species)
0000001 (sample)
0100737 (leukemia cell line sample)
0101035 (hematopoietic cell line sample)
0101883 (acute myeloid leukemia cell line sample)
0100740 (myeloid leukemia cell line sample)
Ancestor terms (development)<b>Summary:</b>Connected ontology terms with develops_from, derives_from or preceded_by relationship <br><b>Analyst:</b> Hideya Kawaji <br><br>link to source data<br>data
CL:0000049 (common myeloid progenitor)
CL:0000134 (mesenchymal cell)