FF:10843-111E6: Difference between revisions
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{{f5samples | {{f5samples | ||
|ancestors_in_anatomy_facet=UBERON: | |DRA_sample_Accession=CAGE@SAMD00005532 | ||
|ancestors_in_cell_lineage_facet=CL:0000000,CL:0000003,CL: | |DRA_sample_Accession_RNASeq=RNA-Seq@SAMD00005532 | ||
|accession_numbers=CAGE;DRX007933;DRR008805;DRZ000230;DRZ001615;DRZ011580;DRZ012965 | |||
|accession_numbers_RNASeq=RNA-Seq;DRX057149;DRR062908;DRZ007984 | |||
|ancestors_in_anatomy_facet=UBERON:0000468,UBERON:0001003,UBERON:0002097,UBERON:0002199,UBERON:0000483,UBERON:0000479,UBERON:0004121,UBERON:0000062,UBERON:0000061,UBERON:0000465,UBERON:0000467,UBERON:0001062,UBERON:0000480,UBERON:0000119,UBERON:0003102,UBERON:0007376,UBERON:0010371,UBERON:0010317,UBERON:0002416 | |||
|ancestors_in_cell_lineage_facet=CL:0000000,CL:0000003,CL:0000548,CL:0000066,CL:0002371,CL:0000076,CL:0002319,CL:0000095,CL:0000325,CL:0000240,CL:0000311,CL:0000079,CL:0000123,CL:0000312,CL:0000237,CL:0000362,CL:0002159,CL:0000255,CL:0002077,CL:0000242 | |||
|ancestors_in_disease_facet=DOID:4,DOID:162,DOID:14566,DOID:0050687,DOID:305 | |||
|ancestors_in_ff_facet=FF:0000102,FF:0000003,FF:0000210,FF:0000101,FF:0000001,FF:0100297,FF:0101120 | |||
|comment= | |comment= | ||
|created_by= | |created_by= | ||
|creation_date= | |creation_date= | ||
|data_phase=2 | |||
|datafreeze_phase=2 | |||
|def= | |def= | ||
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| |expression_enrichment_score=chr13:79177674..79177701,-!p1@POU4F1!2.65!442.11!POU4F1;;chr19:57352087..57352102,-!p1@PEG3,p1@ZIM2!2.64!436.49!PEG3;;chr13:72441315..72441454,-!p1@DACH1!2.58!724.05!DACH1;;chr4:94749897..94749909,+!p1@ATOH1!2.54!345.16!ATOH1;;chr5:145718398..145718410,+!p1@POU4F3!2.50!314.72!POU4F3;;chr9:77112244..77112262,+!p1@RORB!2.49!339.07!RORB;;chr20:20348740..20348757,+!p1@INSM1!2.40!250.56!INSM1;;chr5:50679228..50679288,+!p1@ISL1!2.33!214.97!ISL1;;chr5:2751762..2751784,-!p1@IRX2!2.33!214.03!IRX2;;chr2:239148671..239148686,-!p1@HES6!2.25!612.58!HES6;;chr6:50786591..50786614,+!p1@TFAP2B!2.20!156.42!TFAP2B;;chr1:160336851..160336868,+!p1@NHLH1!2.17!146.12!NHLH1;;chr5:2751785..2751808,-!p2@IRX2!2.16!144.25!IRX2;;chr12:54785054..54785072,-!p4@ZNF385A!2.15!156.89!ZNF385A;;chr5:170736243..170736279,+!p1@TLX3!1.96!89.92!TLX3;;chr3:181429704..181429722,+!p1@SOX2!1.91!79.62!SOX2;;chr12:54785074..54785122,-!p2@ZNF385A!1.90!118.49!ZNF385A;;chr13:72441074..72441172,-!p2@DACH1!1.90!78.21!DACH1;;chr5:145718596..145718607,+!p2@POU4F3!1.89!76.81!POU4F3;;chr7:156803329..156803362,-!p1@MNX1!1.86!71.19!MNX1;;chr15:57511609..57511651,+!p2@TCF12!1.84!111.00!TCF12;;chr6:10415276..10415341,-!p2@TFAP2A!1.80!74.47!TFAP2A;;chrX:85403445..85403479,+!p2@DACH2!1.80!62.76!DACH2;;chr17:37764128..37764258,-!p1@NEUROD2!1.77!58.54!NEUROD2;;chr6:10412600..10412637,-!p1@TFAP2A!1.73!85.24!TFAP2A;;chr6:10415484..10415508,-!p3@TFAP2A!1.73!52.92!TFAP2A;;chr17:48072574..48072597,-!p1@DLX3!1.72!51.99!DLX3;;chr9:139094988..139095012,-!p1@LHX3!1.70!49.18!LHX3;;chr3:18486354..18486377,-!p2@SATB1!1.68!57.61!SATB1;;chr5:134369879..134369898,-!p2@PITX1!1.63!41.21!PITX1;;chr11:31832658..31832681,-!p1@PAX6!1.62!40.75!PAX6;;chr1:197886461..197886558,+!p1@LHX9!1.60!38.87!LHX9;;chr6:50786571..50786590,+!p2@TFAP2B!1.59!37.94!TFAP2B;;chr8:72756637..72756664,-!p3@MSC!1.58!42.15!MSC;;chr17:48046642..48046667,+!p3@DLX4!1.58!37.00!DLX4;;chr1:92949331..92949377,-!p2@GFI1!1.55!34.19!GFI1;;chr15:68115672..68115691,+!p1@SKOR1!1.52!31.85!SKOR1;;chr1:92949195..92949210,-!p7@GFI1!1.51!31.38!GFI1;;chr7:27196217..27196246,-!p2@HOXA7!1.50!30.91!HOXA7;;chr5:134369905..134369972,-!p1@PITX1!1.47!43.09!PITX1;;chr13:79177703..79177729,-!p2@POU4F1!1.47!28.57!POU4F1;;chr2:105470562..105470582,+!p@chr2:105470562..105470582,+!1.47!28.57!POU3F3;;chr5:158526917..158526932,-!p1@EBF1!1.46!68.38!EBF1;;chr4:174451370..174451387,-!p1@HAND2!1.46!28.10!HAND2;;chr6:50786547..50786564,+!p3@TFAP2B!1.46!27.63!TFAP2B;;chr12:54779511..54779577,-!p5@ZNF385A!1.44!26.70!ZNF385A;;chr1:151032922..151032951,+!p2@MLLT11!1.43!42.15!MLLT11;;chr2:166326200..166326216,+!p1@CSRNP3!1.43!37.47!CSRNP3;;chr9:139096968..139096979,-!p2@LHX3!1.42!25.29!LHX3;;chr8:93107451..93107468,-!p2@RUNX1T1!1.42!25.29!RUNX1T1;;chr2:200325452..200325462,-!p33@SATB2!1.41!24.82!SATB2;;chr7:27205136..27205164,-!p1@HOXA9!1.40!23.89!HOXA9;;chr1:23857325..23857416,-!p2@E2F2!1.39!27.63!E2F2;;chr2:219849012..219849065,-!p1@FEV!1.39!23.42!FEV;;chr13:72441506..72441562,-!p3@DACH1!1.39!23.42!DACH1;;chr11:63684602..63684664,-!p1@RCOR2!1.38!44.96!RCOR2;;chr7:31380292..31380351,-!p1@NEUROD6!1.38!22.95!NEUROD6;;chr3:169381420..169381535,-!p1@MECOM!1.37!26.23!MECOM;;chr17:48049323..48049330,+!p6@DLX4!1.37!22.48!DLX4;;chr9:14314131..14314147,-!p2@NFIB!1.36!119.89!NFIB;;chr1:216896752..216896778,-!p1@ESRRG!1.36!22.01!ESRRG;;chr5:176738887..176738934,-!p1@MXD3!1.35!138.16!MXD3;;chr6:50789717..50789729,+!p4@TFAP2B!1.35!21.54!TFAP2B;;chr20:39317868..39317884,-!p1@MAFB!1.33!232.76!MAFB;;chr3:181429741..181429767,+!p2@SOX2!1.33!20.61!SOX2;;chr17:48046671..48046697,+!p4@DLX4!1.33!20.61!DLX4;;chrX:84499081..84499115,+!p2@ZNF711!1.31!28.10!ZNF711;;chr2:5832508..5832524,+!p1@SOX11!1.31!19.20!SOX11;;chr1:61547894..61547968,+!p2@NFIA!1.30!53.86!NFIA;;chr3:40547564..40547616,+!p1@ZNF620!1.28!25.29!ZNF620;;chr2:185463247..185463263,+!p1@ZNF804A!1.27!30.91!ZNF804A;;chr16:67197654..67197716,+!p3@HSF4!1.27!17.80!HSF4;;chr13:79177629..79177636,-!p4@POU4F1!1.26!17.33!POU4F1;;chr11:31832807..31832823,-!p4@PAX6!1.25!16.86!PAX6;;chr5:170736216..170736238,+!p2@TLX3!1.25!16.86!TLX3;;chr8:72756667..72756736,-!p2@MSC!1.24!25.29!MSC;;chrY:21906594..21906622,-!p1@KDM5D!1.24!16.39!KDM5D;;chr18:6414884..6414942,-!p1@L3MBTL4!1.23!20.14!L3MBTL4;;chr4:299227..299272,-!p1@ZNF732!1.23!15.92!ZNF732;;chr19:13134772..13134822,+!p2@NFIX!1.22!22.95!NFIX;;chr2:239149300..239149321,-!p2@HES6!1.22!15.46!HES6;;chr1:23857698..23857733,-!p1@E2F2!1.20!27.16!E2F2;;chr10:48355030..48355090,+!p1@ZNF488!1.20!19.20!ZNF488;;chr1:61548225..61548299,+!p1@NFIA!1.19!188.74!NFIA;;chrX:84498989..84499003,+!p1@ZNF711!1.19!19.67!ZNF711;;chr9:77112225..77112238,+!p2@RORB!1.19!14.52!RORB;;chr9:126774018..126774055,+!p1@LHX2!1.19!14.52!LHX2;;chr13:72440901..72440968,-!p4@DACH1!1.19!14.52!DACH1;;chr9:139095013..139095024,-!p3@LHX3!1.18!14.05!LHX3;;chr15:68117844..68117858,+!p3@SKOR1!1.18!14.05!SKOR1;;chr6:10419768..10419819,-!p6@TFAP2A!1.18!14.05!TFAP2A;;chr1:61548069..61548102,+!p3@NFIA!1.1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| ||
|ffid_belonging_in_development=CL:0000133,CL:0000357,CL:0000114,CL:0000221 | |||
|fonse_cell_line=FF:0101120 | |fonse_cell_line=FF:0101120 | ||
|fonse_cell_line_closure=FF:0101120 | |fonse_cell_line_closure=FF:0101120 | ||
| Line 35: | Line 43: | ||
|fonse_treatment_closure= | |fonse_treatment_closure= | ||
|has_quality= | |has_quality= | ||
|hg19bam=http://fantom.gsc.riken.jp/5/datafiles/latest/basic/human.cell_line.hCAGE/merkel%2520cell%2520carcinoma%2520cell%2520line%253aMKL-1.CNhs12838.10843-111E6.hg19.nobarcode.bam | |||
|hg19ctss=http://fantom.gsc.riken.jp/5/datafiles/latest/basic/human.cell_line.hCAGE/merkel%2520cell%2520carcinoma%2520cell%2520line%253aMKL-1.CNhs12838.10843-111E6.hg19.ctss.bed.gz | |||
|hg19fasta=http://fantom.gsc.riken.jp/5/datafiles/latest/basic/human.cell_line.hCAGE/merkel%2520cell%2520carcinoma%2520cell%2520line%253aMKL-1.CNhs12838.10843-111E6.hg19.nobarcode.rdna.fa.gz | |||
|hg38bam=http://fantom.gsc.riken.jp/5/datafiles/reprocessed/hg38_v2/basic/human.cell_line.hCAGE/merkel%2520cell%2520carcinoma%2520cell%2520line%253aMKL-1.CNhs12838.10843-111E6.hg38.nobarcode.bam | |||
|hg38ctss=http://fantom.gsc.riken.jp/5/datafiles/reprocessed/hg38_v2/basic/human.cell_line.hCAGE/merkel%2520cell%2520carcinoma%2520cell%2520line%253aMKL-1.CNhs12838.10843-111E6.hg38.nobarcode.ctss.bed.gz | |||
|id=FF:10843-111E6 | |id=FF:10843-111E6 | ||
|is_a=CL:0000242;;EFO:0002091;;FF: | |is_a=CL:0000242;;EFO:0002091;;FF:0000210;;FF:0100297 | ||
|is_obsolete= | |||
|library_id=CNhs12838 | |||
|library_id_phase_based=2:CNhs12838 | |||
|microRNAs= | |||
|microRNAs_nn= | |||
|microRNAs_nonnovel_cage=http://fantom.gsc.riken.jp/5/suppl/De_Rie_et_al_2017/vis_viewer/#/human#cage;sample;10843 | |||
|microRNAs_novel_cage=http://fantom.gsc.riken.jp/5/suppl/De_Rie_et_al_2017/vis_viewer_novel/#/human#cage;sample;10843 | |||
|name=merkel cell carcinoma cell line:MKL-1 | |name=merkel cell carcinoma cell line:MKL-1 | ||
|namespace=FANTOM5 | |namespace=FANTOM5 | ||
| Line 42: | Line 62: | ||
|profile_cagescan=,,, | |profile_cagescan=,,, | ||
|profile_hcage=CNhs12838,LSID973,release012,COMPLETED | |profile_hcage=CNhs12838,LSID973,release012,COMPLETED | ||
|profile_rnaseq= | |profile_rnaseq= | ||
|profile_srnaseq=,,, | |profile_srnaseq=,,, | ||
|refex=http://refex.dbcls.jp/genelist.php?lang | |||
|repeat_enrich_byfamily=0,0,0.14352779145979,0,0,0,0,-0.160318030086386,0,0.479771032013861,0.318424120614209,0,0,0,0,0,0,0,0,0,0,0,0.166825123124581,0,0.227792922231587,0,0,0,0,0,0.0688672268565234,0,0,0.498319145862255,0,0,0,0,0,0,0,0,0,0,0,0,0.306640323519836,0.166825123124581,0,0,0,0,0,0,0,0.059197540449456,0,0,0,0,0,0,0.166825123124581,0.190063221676976,0,0,0.283772305366917,0,0,0,0,0,0,0,0,0.287055582919581,0,0,0,0,0,0,0,0,0.0838190208248572,0,0,0,0,0,0,0.0569083637073688,0.0834125615622905,0,0,0.137567143092435,0.166104762414107,0.14352779145979,0,0,0,-0.0980353512377064,0.322237525871371,0,0,0,0,0,0,0,0,0,0.0834125615622905,0,0,0,0,0,0,0,0.219264273898098,0.287055582919581,0,0,0.496435395908439,0.979554497466599,0,0,0.166825123124581,0,0,0 | |||
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| |||
|rna_box=111 | |rna_box=111 | ||
|rna_catalog_number= | |rna_catalog_number= | ||
| Line 54: | Line 77: | ||
|rna_rin= | |rna_rin= | ||
|rna_sample_type=total RNA | |rna_sample_type=total RNA | ||
|rna_tube_id= | |rna_tube_id=1.11E+08 | ||
|rna_weight_ug=31.35898 | |rna_weight_ug=31.35898 | ||
|rnaseq_library_id=RDhi10092 | |||
|sample_age=26 | |sample_age=26 | ||
|sample_category=cell lines | |||
|sample_cell_catalog=9111801 | |sample_cell_catalog=9111801 | ||
|sample_cell_line=MKL-1 | |sample_cell_line=MKL-1 | ||
| Line 69: | Line 94: | ||
|sample_ethnicity=C | |sample_ethnicity=C | ||
|sample_experimental_condition= | |sample_experimental_condition= | ||
|sample_gostat=GO:0044464;cell part;0!GO:0005622;intracellular;0!GO:0044424;intracellular part;4.6627950529237e-299!GO:0043226;organelle;7.50820433518173e-272!GO:0043229;intracellular organelle;1.44377794854598e-271!GO:0043231;intracellular membrane-bound organelle;3.10562444027327e-270!GO:0043227;membrane-bound organelle;1.00536811553645e-269!GO:0044422;organelle part;3.74090610699503e-174!GO:0044446;intracellular organelle part;2.12592699895992e-173!GO:0005634;nucleus;3.68269040424078e-159!GO:0005737;cytoplasm;2.61566378924845e-138!GO:0032991;macromolecular complex;1.19684423309721e-116!GO:0044237;cellular metabolic process;3.97040239009454e-115!GO:0044238;primary metabolic process;3.07774868948989e-110!GO:0043170;macromolecule metabolic process;1.01298126441572e-108!GO:0044428;nuclear part;5.99210844770691e-101!GO:0044444;cytoplasmic part;5.39778382368093e-99!GO:0006139;nucleobase, nucleoside, nucleotide and nucleic acid metabolic process;3.51309659695973e-96!GO:0030529;ribonucleoprotein complex;5.08318337271358e-88!GO:0043283;biopolymer metabolic process;3.13409951074051e-87!GO:0003723;RNA binding;1.85567194100104e-85!GO:0043233;organelle lumen;2.28385846745238e-82!GO:0031974;membrane-enclosed lumen;2.28385846745238e-82!GO:0010467;gene expression;2.28385846745238e-82!GO:0003676;nucleic acid binding;7.92038941261225e-70!GO:0006396;RNA processing;1.27293637347096e-62!GO:0005739;mitochondrion;2.03737918825495e-62!GO:0043234;protein complex;1.0017730916831e-61!GO:0006259;DNA metabolic process;7.4829482496559e-59!GO:0016043;cellular component organization and biogenesis;3.16353772413037e-57!GO:0031981;nuclear lumen;1.03741845556534e-55!GO:0016070;RNA metabolic process;3.97943255160334e-54!GO:0006996;organelle organization and biogenesis;1.95477480198813e-53!GO:0005515;protein binding;2.86085162954057e-53!GO:0016071;mRNA metabolic process;5.36026827955597e-50!GO:0043228;non-membrane-bound organelle;1.12853961643939e-48!GO:0043232;intracellular non-membrane-bound organelle;1.12853961643939e-48!GO:0008380;RNA splicing;8.08076712834318e-47!GO:0005840;ribosome;9.42042110027606e-47!GO:0044429;mitochondrial part;1.24071508250207e-44!GO:0031967;organelle envelope;1.63948023427523e-44!GO:0031090;organelle membrane;3.95978687321613e-44!GO:0031975;envelope;3.98944981140099e-44!GO:0006397;mRNA processing;4.70190284255722e-44!GO:0006412;translation;5.16956857612306e-40!GO:0003735;structural constituent of ribosome;1.74469543646011e-39!GO:0033036;macromolecule localization;3.15854228031562e-39!GO:0005694;chromosome;8.84991763226875e-38!GO:0015031;protein transport;3.45130680514201e-37!GO:0007049;cell cycle;6.12024913683526e-37!GO:0005654;nucleoplasm;4.59799498860277e-35!GO:0033279;ribosomal subunit;4.85244083743014e-35!GO:0046907;intracellular transport;8.63013956336485e-35!GO:0008104;protein localization;2.00066373904857e-34!GO:0065003;macromolecular complex assembly;3.7881921979445e-34!GO:0022613;ribonucleoprotein complex biogenesis and assembly;9.77686576485223e-34!GO:0045184;establishment of protein localization;5.71380690056734e-33!GO:0051276;chromosome organization and biogenesis;1.24832029707805e-32!GO:0005681;spliceosome;1.26450649841919e-32!GO:0044427;chromosomal part;1.75138935272524e-32!GO:0000166;nucleotide binding;2.49685931862957e-31!GO:0022607;cellular component assembly;3.03343030420058e-31!GO:0006974;response to DNA damage stimulus;3.21785629289349e-31!GO:0006281;DNA repair;3.5743844490521e-30!GO:0044249;cellular biosynthetic process;4.88977567532815e-30!GO:0009058;biosynthetic process;9.99782664376097e-30!GO:0009059;macromolecule biosynthetic process;3.26343794023785e-29!GO:0019538;protein metabolic process;1.05407463162224e-28!GO:0000278;mitotic cell cycle;1.76933727072172e-28!GO:0005740;mitochondrial envelope;3.14109168453772e-28!GO:0022402;cell cycle process;7.25729468086114e-28!GO:0051649;establishment of cellular localization;8.93122122887401e-28!GO:0044451;nucleoplasm part;9.14807288605396e-28!GO:0019866;organelle inner membrane;9.66083644279382e-28!GO:0051641;cellular localization;5.30568372897616e-27!GO:0044267;cellular protein metabolic process;8.27133358590919e-27!GO:0031966;mitochondrial membrane;3.12756298607979e-26!GO:0044260;cellular macromolecule metabolic process;3.37884999630936e-26!GO:0016462;pyrophosphatase activity;8.78920920797341e-26!GO:0022403;cell cycle phase;1.272030479535e-25!GO:0016818;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides;1.27568589940759e-25!GO:0006325;establishment and/or maintenance of chromatin architecture;1.31205045106082e-25!GO:0016817;hydrolase activity, acting on acid anhydrides;1.49193781891822e-25!GO:0017111;nucleoside-triphosphatase activity;3.35565621341328e-25!GO:0000087;M phase of mitotic cell cycle;5.4604248748023e-25!GO:0005743;mitochondrial inner membrane;8.37917775611851e-25!GO:0005829;cytosol;8.41941766105936e-25!GO:0006323;DNA packaging;1.11184788027998e-24!GO:0006886;intracellular protein transport;1.40945588743126e-24!GO:0007067;mitosis;2.16439418624638e-24!GO:0005830;cytosolic ribosome (sensu Eukaryota);6.54779069944807e-24!GO:0000279;M phase;3.45016085912234e-23!GO:0006119;oxidative phosphorylation;4.04194649547413e-23!GO:0006260;DNA replication;9.5371216976085e-23!GO:0051301;cell division;1.42073628537703e-21!GO:0044445;cytosolic part;2.6588243573675e-21!GO:0044455;mitochondrial membrane part;2.84639033220006e-21!GO:0005730;nucleolus;1.04907546790152e-20!GO:0032553;ribonucleotide binding;1.52682202772725e-20!GO:0032555;purine ribonucleotide binding;1.52682202772725e-20!GO:0005524;ATP binding;1.92091629436137e-20!GO:0016887;ATPase activity;2.48880329712743e-20!GO:0022618;protein-RNA complex assembly;3.54219768637175e-20!GO:0031980;mitochondrial lumen;6.6807570502727e-20!GO:0005759;mitochondrial matrix;6.6807570502727e-20!GO:0032559;adenyl ribonucleotide binding;1.33471896750604e-19!GO:0009719;response to endogenous stimulus;1.33471896750604e-19!GO:0017076;purine nucleotide binding;1.77377176818627e-19!GO:0042623;ATPase activity, coupled;3.99961198836016e-19!GO:0031965;nuclear membrane;5.68765947931255e-19!GO:0006350;transcription;1.04450009491811e-18!GO:0015935;small ribosomal subunit;1.06922867508588e-18!GO:0019222;regulation of metabolic process;1.76296306347856e-18!GO:0006333;chromatin assembly or disassembly;2.20848673361377e-18!GO:0030554;adenyl nucleotide binding;3.26792116798458e-18!GO:0006512;ubiquitin cycle;4.02153350902611e-18!GO:0000785;chromatin;4.08702786444566e-18!GO:0012505;endomembrane system;5.29451169812535e-18!GO:0005635;nuclear envelope;1.48700015637359e-17!GO:0015934;large ribosomal subunit;1.57154542452665e-17!GO:0005746;mitochondrial respiratory chain;1.9966752928938e-17!GO:0015630;microtubule cytoskeleton;2.29888485841914e-17!GO:0003677;DNA binding;7.74678694122515e-17!GO:0044453;nuclear membrane part;8.41893806530037e-17!GO:0016604;nuclear body;8.74122273556883e-17!GO:0016874;ligase activity;1.12035664780627e-16!GO:0008135;translation factor activity, nucleic acid binding;1.60200296541879e-16!GO:0000398;nuclear mRNA splicing, via spliceosome;2.4408913969385e-16!GO:0000375;RNA splicing, via transesterification reactions;2.4408913969385e-16!GO:0000377;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile;2.4408913969385e-16!GO:0050136;NADH dehydrogenase (quinone) activity;3.00336254873774e-16!GO:0003954;NADH dehydrogenase activity;3.00336254873774e-16!GO:0008137;NADH dehydrogenase (ubiquinone) activity;3.00336254873774e-16!GO:0032774;RNA biosynthetic process;3.02440396781353e-16!GO:0008134;transcription factor binding;3.42467150565529e-16!GO:0031323;regulation of cellular metabolic process;5.21645155874204e-16!GO:0006351;transcription, DNA-dependent;5.46829599138809e-16!GO:0019219;regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process;8.46602421931714e-16!GO:0006457;protein folding;1.155663124617e-15!GO:0044265;cellular macromolecule catabolic process;1.19975216344214e-15!GO:0065004;protein-DNA complex assembly;1.63935326404309e-15!GO:0010468;regulation of gene expression;2.00731610232363e-15!GO:0004386;helicase activity;2.48120143503382e-15!GO:0016568;chromatin modification;3.21935127859761e-15!GO:0016655;oxidoreductase activity, acting on NADH or NADPH, quinone or similar compound as acceptor;6.04693784624294e-15!GO:0005643;nuclear pore;9.18822174889406e-15!GO:0006511;ubiquitin-dependent protein catabolic process;9.87941250069774e-15!GO:0005761;mitochondrial ribosome;1.47671812787259e-14!GO:0000313;organellar ribosome;1.47671812787259e-14!GO:0051603;proteolysis involved in cellular protein catabolic process;2.17615794138474e-14!GO:0042254;ribosome biogenesis and assembly;2.38329423841099e-14!GO:0019941;modification-dependent protein catabolic process;2.48319890975869e-14!GO:0043632;modification-dependent macromolecule catabolic process;2.48319890975869e-14!GO:0016607;nuclear speck;3.44387702857333e-14!GO:0050657;nucleic acid transport;3.45652938022263e-14!GO:0051236;establishment of RNA localization;3.45652938022263e-14!GO:0050658;RNA transport;3.45652938022263e-14!GO:0030964;NADH dehydrogenase complex (quinone);4.30406992335865e-14!GO:0045271;respiratory chain complex I;4.30406992335865e-14!GO:0005747;mitochondrial respiratory chain complex I;4.30406992335865e-14!GO:0042775;organelle ATP synthesis coupled electron transport;5.3122135044155e-14!GO:0042773;ATP synthesis coupled electron transport;5.3122135044155e-14!GO:0006403;RNA localization;5.86220006723593e-14!GO:0045449;regulation of transcription;5.89195937738363e-14!GO:0051082;unfolded protein binding;6.59293411040232e-14!GO:0044257;cellular protein catabolic process;6.60834363766698e-14!GO:0006120;mitochondrial electron transport, NADH to ubiquinone;1.48795609843268e-13!GO:0008026;ATP-dependent helicase activity;2.32497304873572e-13!GO:0005843;cytosolic small ribosomal subunit (sensu Eukaryota);2.70969980977032e-13!GO:0006355;regulation of transcription, DNA-dependent;6.85425487107483e-13!GO:0043285;biopolymer catabolic process;7.48641040618439e-13!GO:0031497;chromatin assembly;1.01668144768129e-12!GO:0000775;chromosome, pericentric region;1.25593771185494e-12!GO:0009057;macromolecule catabolic process;1.54404334318306e-12!GO:0003743;translation initiation factor activity;1.60677440470856e-12!GO:0006334;nucleosome assembly;1.85688869556147e-12!GO:0006413;translational initiation;2.39515176467947e-12!GO:0043566;structure-specific DNA binding;2.86672940382444e-12!GO:0046930;pore complex;3.68226900381549e-12!GO:0051028;mRNA transport;3.95639405030284e-12!GO:0015931;nucleobase, nucleoside, nucleotide and nucleic acid transport;4.97951715385137e-12!GO:0000502;proteasome complex (sensu Eukaryota);5.11444507803667e-12!GO:0050794;regulation of cellular process;6.31980072027866e-12!GO:0003697;single-stranded DNA binding;1.31936658843273e-11!GO:0005842;cytosolic large ribosomal subunit (sensu Eukaryota);1.76884557470636e-11!GO:0016651;oxidoreductase activity, acting on NADH or NADPH;3.45881272185914e-11!GO:0006261;DNA-dependent DNA replication;4.18829616735276e-11!GO:0006605;protein targeting;4.20012634225833e-11!GO:0005819;spindle;4.43818574854565e-11!GO:0006446;regulation of translational initiation;5.70075939858591e-11!GO:0005794;Golgi apparatus;8.14001775615082e-11!GO:0009259;ribonucleotide metabolic process;1.09914451561722e-10!GO:0006364;rRNA processing;1.622837294779e-10!GO:0065002;intracellular protein transport across a membrane;1.70489314631711e-10!GO:0006163;purine nucleotide metabolic process;1.73885542410333e-10!GO:0051726;regulation of cell cycle;1.93452786193452e-10!GO:0006399;tRNA metabolic process;1.93452786193452e-10!GO:0046961;hydrogen ion transporting ATPase activity, rotational mechanism;2.01715296467452e-10!GO:0051186;cofactor metabolic process;2.05578911410139e-10!GO:0048770;pigment granule;2.29379579849953e-10!GO:0042470;melanosome;2.29379579849953e-10!GO:0043412;biopolymer modification;2.29379579849953e-10!GO:0030163;protein catabolic process;2.62749945840919e-10!GO:0044248;cellular catabolic process;2.72120786906984e-10!GO:0016072;rRNA metabolic process;3.13584062487221e-10!GO:0030532;small nuclear ribonucleoprotein complex;3.49874547207896e-10!GO:0019829;cation-transporting ATPase activity;3.6989563179693e-10!GO:0016192;vesicle-mediated transport;4.35838543016182e-10!GO:0048193;Golgi vesicle transport;5.01103449780402e-10!GO:0003712;transcription cofactor activity;5.0425722837453e-10!GO:0006913;nucleocytoplasmic transport;6.25353410539229e-10!GO:0000074;regulation of progression through cell cycle;6.4773541930572e-10!GO:0008565;protein transporter activity;6.91446936083205e-10!GO:0006164;purine nucleotide biosynthetic process;1.1957532509953e-09!GO:0008094;DNA-dependent ATPase activity;1.19717456190704e-09!GO:0051169;nuclear transport;1.36314000076904e-09!GO:0009260;ribonucleotide biosynthetic process;1.70107186662066e-09!GO:0009150;purine ribonucleotide metabolic process;1.74454724542545e-09!GO:0005874;microtubule;1.93409917476504e-09!GO:0046933;hydrogen ion transporting ATP synthase activity, rotational mechanism;2.65515036600252e-09!GO:0007017;microtubule-based process;3.6188008238991e-09!GO:0006366;transcription from RNA polymerase II promoter;4.19596439286504e-09!GO:0006732;coenzyme metabolic process;4.97494761323058e-09!GO:0009055;electron carrier activity;5.4844128545228e-09!GO:0009199;ribonucleoside triphosphate metabolic process;7.86672167534558e-09!GO:0016591;DNA-directed RNA polymerase II, holoenzyme;8.33659324045954e-09!GO:0009141;nucleoside triphosphate metabolic process;8.38647268004898e-09!GO:0016779;nucleotidyltransferase activity;8.99064665638209e-09!GO:0006464;protein modification process;1.01737914572566e-08!GO:0050789;regulation of biological process;1.09411668115666e-08!GO:0044432;endoplasmic reticulum part;1.17280213856314e-08!GO:0009152;purine ribonucleotide biosynthetic process;1.20903167580123e-08!GO:0005657;replication fork;1.79108083322457e-08!GO:0005783;endoplasmic reticulum;1.8666453178314e-08!GO:0015986;ATP synthesis coupled proton transport;1.91102408175433e-08!GO:0015985;energy coupled proton transport, down electrochemical gradient;1.91102408175433e-08!GO:0000245;spliceosome assembly;1.95481642846981e-08!GO:0009205;purine ribonucleoside triphosphate metabolic process;1.99643399981232e-08!GO:0009144;purine nucleoside triphosphate metabolic process;1.99643399981232e-08!GO:0005813;centrosome;2.54374671111206e-08!GO:0005815;microtubule organizing center;2.85672574649841e-08!GO:0009142;nucleoside triphosphate biosynthetic process;2.97121137553562e-08!GO:0009201;ribonucleoside triphosphate biosynthetic process;2.97121137553562e-08!GO:0009060;aerobic respiration;3.0772815129398e-08!GO:0015078;hydrogen ion transmembrane transporter activity;4.09768670549984e-08!GO:0007051;spindle organization and biogenesis;4.38019325219979e-08!GO:0046034;ATP metabolic process;5.77358671555983e-08!GO:0003682;chromatin binding;6.06234234135008e-08!GO:0007059;chromosome segregation;6.82097387397218e-08!GO:0009206;purine ribonucleoside triphosphate biosynthetic process;7.89907826844626e-08!GO:0009145;purine nucleoside triphosphate biosynthetic process;7.89907826844626e-08!GO:0016876;ligase activity, forming aminoacyl-tRNA and related compounds;8.39175604430241e-08!GO:0004812;aminoacyl-tRNA ligase activity;8.39175604430241e-08!GO:0016875;ligase activity, forming carbon-oxygen bonds;8.39175604430241e-08!GO:0043687;post-translational protein modification;1.14229733442203e-07!GO:0016879;ligase activity, forming carbon-nitrogen bonds;1.26524428408359e-07!GO:0045333;cellular respiration;1.29101958781364e-07!GO:0016469;proton-transporting two-sector ATPase complex;1.56321622416635e-07!GO:0031202;RNA splicing factor activity, transesterification mechanism;1.75476348027318e-07!GO:0006754;ATP biosynthetic process;1.84001292550034e-07!GO:0006753;nucleoside phosphate metabolic process;1.84001292550034e-07!GO:0000226;microtubule cytoskeleton organization and biogenesis;1.84001292550034e-07!GO:0043038;amino acid activation;2.20990493166559e-07!GO:0006418;tRNA aminoacylation for protein translation;2.20990493166559e-07!GO:0043039;tRNA aminoacylation;2.20990493166559e-07!GO:0043623;cellular protein complex assembly;2.49910383659093e-07!GO:0008639;small protein conjugating enzyme activity;3.46958569493187e-07!GO:0003899;DNA-directed RNA polymerase activity;5.45343280883568e-07!GO:0019787;small conjugating protein ligase activity;5.46416297861243e-07!GO:0000075;cell cycle checkpoint;6.3395596763106e-07!GO:0044431;Golgi apparatus part;6.64393240122075e-07!GO:0004842;ubiquitin-protein ligase activity;7.14268660984271e-07!GO:0055086;nucleobase, nucleoside and nucleotide metabolic process;7.48419322762403e-07!GO:0006302;double-strand break repair;7.9768065641641e-07!GO:0051329;interphase of mitotic cell cycle;8.22894971432778e-07!GO:0032446;protein modification by small protein conjugation;8.57837636413835e-07!GO:0015077;monovalent inorganic cation transmembrane transporter activity;9.93321936103877e-07!GO:0006084;acetyl-CoA metabolic process;1.03122353938639e-06!GO:0000786;nucleosome;1.09140833949881e-06!GO:0017038;protein import;1.15918172803307e-06!GO:0045259;proton-transporting ATP synthase complex;1.2367651268219e-06!GO:0042175;nuclear envelope-endoplasmic reticulum network;1.2367651268219e-06!GO:0003724;RNA helicase activity;1.24821295020942e-06!GO:0006099;tricarboxylic acid cycle;1.27012049598038e-06!GO:0046356;acetyl-CoA catabolic process;1.27012049598038e-06!GO:0007005;mitochondrion organization and biogenesis;1.34811749723544e-06!GO:0042625;ATPase activity, coupled to transmembrane movement of ions;1.35476388709462e-06!GO:0000776;kinetochore;1.46490288416973e-06!GO:0051325;interphase;1.64059826064418e-06!GO:0005667;transcription factor complex;2.17182604388483e-06!GO:0005789;endoplasmic reticulum membrane;2.31994253702946e-06!GO:0000228;nuclear chromosome;2.41735534376733e-06!GO:0016363;nuclear matrix;2.44172849975898e-06!GO:0007010;cytoskeleton organization and biogenesis;2.53296609950697e-06!GO:0016567;protein ubiquitination;2.60765500967048e-06!GO:0006461;protein complex assembly;2.70300496226328e-06!GO:0003729;mRNA binding;3.1654397623727e-06!GO:0006752;group transfer coenzyme metabolic process;3.31258990551725e-06!GO:0016881;acid-amino acid ligase activity;3.53241556319236e-06!GO:0000151;ubiquitin ligase complex;3.74459218914773e-06!GO:0051168;nuclear export;4.72788610007711e-06!GO:0048475;coated membrane;5.00925198125045e-06!GO:0030117;membrane coat;5.00925198125045e-06!GO:0003678;DNA helicase activity;5.86325925282936e-06!GO:0051188;cofactor biosynthetic process;6.14829226593764e-06!GO:0003690;double-stranded DNA binding;1.01848179489431e-05!GO:0006310;DNA recombination;1.0232823889048e-05!GO:0008168;methyltransferase activity;1.07828835185627e-05!GO:0005768;endosome;1.07828835185627e-05!GO:0016741;transferase activity, transferring one-carbon groups;1.12545146333262e-05!GO:0009117;nucleotide metabolic process;1.20598124573981e-05!GO:0005762;mitochondrial large ribosomal subunit;1.3005564997126e-05!GO:0000315;organellar large ribosomal subunit;1.3005564997126e-05!GO:0009109;coenzyme catabolic process;1.36422613722078e-05!GO:0016740;transferase activity;1.42625874567619e-05!GO:0015631;tubulin binding;1.67838486094615e-05!GO:0006613;cotranslational protein targeting to membrane;1.75774048727002e-05!GO:0003713;transcription coactivator activity;1.83354984642335e-05!GO:0000792;heterochromatin;1.92057841935678e-05!GO:0045045;secretory pathway;2.08179878758721e-05!GO:0000139;Golgi membrane;2.48169501977687e-05!GO:0030530;heterogeneous nuclear ribonucleoprotein complex;2.54599612464004e-05!GO:0003684;damaged DNA binding;2.87562425883278e-05!GO:0009108;coenzyme biosynthetic process;3.33183856254958e-05!GO:0008186;RNA-dependent ATPase activity;3.98557271968614e-05!GO:0030120;vesicle coat;4.82626773091502e-05!GO:0030662;coated vesicle membrane;4.82626773091502e-05!GO:0016772;transferase activity, transferring phosphorus-containing groups;4.95152889968296e-05!GO:0008022;protein C-terminus binding;6.00265770472527e-05!GO:0044440;endosomal part;6.07377485165684e-05!GO:0010008;endosome membrane;6.07377485165684e-05!GO:0006888;ER to Golgi vesicle-mediated transport;6.49017130386509e-05!GO:0000314;organellar small ribosomal subunit;6.5537246309334e-05!GO:0005763;mitochondrial small ribosomal subunit;6.5537246309334e-05!GO:0006383;transcription from RNA polymerase III promoter;6.88648446009311e-05!GO:0051427;hormone receptor binding;7.78011553156407e-05!GO:0009056;catabolic process;7.99391075664336e-05!GO:0051187;cofactor catabolic process;8.08096929233119e-05!GO:0006338;chromatin remodeling;8.62137757868308e-05!GO:0032508;DNA duplex unwinding;0.000110266826952035!GO:0032392;DNA geometric change;0.000110266826952035!GO:0007088;regulation of mitosis;0.000111744036420812!GO:0000059;protein import into nucleus, docking;0.000121273313880855!GO:0016023;cytoplasmic membrane-bound vesicle;0.000122691657308641!GO:0015405;P-P-bond-hydrolysis-driven transmembrane transporter activity;0.000127493434649921!GO:0015399;primary active transmembrane transporter activity;0.000127493434649921!GO:0031988;membrane-bound vesicle;0.00012772707555687!GO:0004004;ATP-dependent RNA helicase activity;0.000128719234917842!GO:0006405;RNA export from nucleus;0.000136465716326874!GO:0006357;regulation of transcription from RNA polymerase II promoter;0.000154470918102184!GO:0008654;phospholipid biosynthetic process;0.000155355319423547!GO:0006284;base-excision repair;0.000168224081533731!GO:0035257;nuclear hormone receptor binding;0.000172102808692587!GO:0004527;exonuclease activity;0.000173740805278962!GO:0007052;mitotic spindle organization and biogenesis;0.000176046976307485!GO:0031982;vesicle;0.00018858358145596!GO:0044454;nuclear chromosome part;0.000189068852154442!GO:0006839;mitochondrial transport;0.000191967999162626!GO:0009165;nucleotide biosynthetic process;0.000197065487812937!GO:0031410;cytoplasmic vesicle;0.000200336922993335!GO:0005876;spindle microtubule;0.000214963556222898!GO:0006414;translational elongation;0.000218016946634459!GO:0043021;ribonucleoprotein binding;0.000223257851253801!GO:0006270;DNA replication initiation;0.000229713776105844!GO:0005793;ER-Golgi intermediate compartment;0.000229713776105844!GO:0031072;heat shock protein binding;0.000233072337002915!GO:0008270;zinc ion binding;0.000238538655648174!GO:0000819;sister chromatid segregation;0.00024035601303734!GO:0005798;Golgi-associated vesicle;0.000253776149153025!GO:0006268;DNA unwinding during replication;0.000290091023815601!GO:0006352;transcription initiation;0.000292364237918436!GO:0005637;nuclear inner membrane;0.000303171985614768!GO:0008033;tRNA processing;0.000305918418487372!GO:0051170;nuclear import;0.000307073863833904!GO:0007006;mitochondrial membrane organization and biogenesis;0.000311071490724396!GO:0000070;mitotic sister chromatid segregation;0.000319637642242512!GO:0003924;GTPase activity;0.000326410785597774!GO:0065007;biological regulation;0.000337950764466155!GO:0048471;perinuclear region of cytoplasm;0.000353037517601539!GO:0044452;nucleolar part;0.000389447765089307!GO:0004003;ATP-dependent DNA helicase activity;0.000389447765089307!GO:0008017;microtubule binding;0.00039196314737884!GO:0005753;mitochondrial proton-transporting ATP synthase complex;0.000394467518629828!GO:0043596;nuclear replication fork;0.000397023450955704!GO:0046474;glycerophospholipid biosynthetic process;0.00040136234869454!GO:0003714;transcription corepressor activity;0.0004204965783264!GO:0005684;U2-dependent spliceosome;0.00042267566738616!GO:0006606;protein import into nucleus;0.000422981223383211!GO:0016853;isomerase activity;0.000425611163887566!GO:0000922;spindle pole;0.000429653689288221!GO:0016787;hydrolase activity;0.000442680139487304!GO:0031124;mRNA 3'-end processing;0.000489263818264099!GO:0033178;proton-transporting two-sector ATPase complex, catalytic domain;0.000573508788545635!GO:0045261;proton-transporting ATP synthase complex, catalytic core F(1);0.000591067185965325!GO:0005852;eukaryotic translation initiation factor 3 complex;0.000596757060095657!GO:0042393;histone binding;0.000603572157687055!GO:0004674;protein serine/threonine kinase activity;0.0006367271329134!GO:0016679;oxidoreductase activity, acting on diphenols and related substances as donors;0.000707015238550385!GO:0016681;oxidoreductase activity, acting on diphenols and related substances as donors, cytochrome as acceptor;0.000707015238550385!GO:0008121;ubiquinol-cytochrome-c reductase activity;0.000707015238550385!GO:0043681;protein import into mitochondrion;0.000715982667827281!GO:0003711;transcription elongation regulator activity;0.000773064398008093!GO:0005048;signal sequence binding;0.000862475874820362!GO:0043492;ATPase activity, coupled to movement of substances;0.000871895837290097!GO:0015992;proton transport;0.000873598845111804!GO:0006289;nucleotide-excision repair;0.000935188279571044!GO:0030118;clathrin coat;0.000947755331161511!GO:0006818;hydrogen transport;0.000963468577005282!GO:0006793;phosphorus metabolic process;0.000963468577005282!GO:0006796;phosphate metabolic process;0.000963468577005282!GO:0051052;regulation of DNA metabolic process;0.00097782909469451!GO:0008276;protein methyltransferase activity;0.00104680976906416!GO:0016564;transcription repressor activity;0.00105236562855919!GO:0032259;methylation;0.00114939133698753!GO:0007093;mitotic cell cycle checkpoint;0.0011655937631336!GO:0046489;phosphoinositide biosynthetic process;0.00120441469773417!GO:0048500;signal recognition particle;0.00120519686471499!GO:0000287;magnesium ion binding;0.00120519686471499!GO:0042626;ATPase activity, coupled to transmembrane movement of substances;0.00120903520595758!GO:0016859;cis-trans isomerase activity;0.00121459463139831!GO:0000790;nuclear chromatin;0.00122188548296733!GO:0019867;outer membrane;0.0012766219843149!GO:0000725;recombinational repair;0.0013147421886204!GO:0000724;double-strand break repair via homologous recombination;0.0013147421886204!GO:0005905;coated pit;0.00132052046454724!GO:0016820;hydrolase activity, acting on acid anhydrides, catalyzing transmembrane movement of substances;0.0013391710240763!GO:0004576;oligosaccharyl transferase activity;0.00134803616803754!GO:0000079;regulation of cyclin-dependent protein kinase activity;0.00135964544948117!GO:0003755;peptidyl-prolyl cis-trans isomerase activity;0.00135964544948117!GO:0006626;protein targeting to mitochondrion;0.00137805126265919!GO:0031123;RNA 3'-end processing;0.00138137501884272!GO:0006612;protein targeting to membrane;0.00141996143557406!GO:0005839;proteasome core complex (sensu Eukaryota);0.00143277245016588!GO:0031968;organelle outer membrane;0.00144530784921218!GO:0016126;sterol biosynthetic process;0.00147586201482927!GO:0005838;proteasome regulatory particle (sensu Eukaryota);0.00148463699475471!GO:0005741;mitochondrial outer membrane;0.00150488382216477!GO:0051920;peroxiredoxin activity;0.00153532056794579!GO:0030880;RNA polymerase complex;0.00153532056794579!GO:0040029;regulation of gene expression, epigenetic;0.0016467867361292!GO:0016310;phosphorylation;0.00184029568568786!GO:0003702;RNA polymerase II transcription factor activity;0.00189581342249232!GO:0000184;mRNA catabolic process, nonsense-mediated decay;0.00191949210986561!GO:0006378;mRNA polyadenylation;0.00192774030932555!GO:0007018;microtubule-based movement;0.00193148249252552!GO:0008312;7S RNA binding;0.00193606062715282!GO:0005875;microtubule associated complex;0.00193606062715282!GO:0008139;nuclear localization sequence binding;0.00194608588569774!GO:0005788;endoplasmic reticulum lumen;0.0019991620927915!GO:0006402;mRNA catabolic process;0.00200080113250275!GO:0008250;oligosaccharyl transferase complex;0.00211351590293077!GO:0005525;GTP binding;0.00215708134617028!GO:0004518;nuclease activity;0.00220719135312526!GO:0019783;small conjugating protein-specific protease activity;0.00232770000919903!GO:0006401;RNA catabolic process;0.00233254407887126!GO:0006730;one-carbon compound metabolic process;0.00235004693261007!GO:0045263;proton-transporting ATP synthase complex, coupling factor F(o);0.00241204023652308!GO:0033177;proton-transporting two-sector ATPase complex, proton-transporting domain;0.00241204023652308!GO:0005770;late endosome;0.00244069976370667!GO:0051087;chaperone binding;0.00253041145822375!GO:0051287;NAD binding;0.00256026028932761!GO:0016563;transcription activator activity;0.00267609620727967!GO:0000910;cytokinesis;0.00272990333645493!GO:0016251;general RNA polymerase II transcription factor activity;0.0027389698265442!GO:0004579;dolichyl-diphosphooligosaccharide-protein glycotransferase activity;0.00274885806424743!GO:0046467;membrane lipid biosynthetic process;0.00277156996390465!GO:0043601;nuclear replisome;0.0030676912685066!GO:0030894;replisome;0.0030676912685066!GO:0035258;steroid hormone receptor binding;0.00308195357793675!GO:0000049;tRNA binding;0.00315366927996528!GO:0005786;signal recognition particle, endoplasmic reticulum targeting;0.00315366927996528!GO:0005769;early endosome;0.00319618989044871!GO:0004843;ubiquitin-specific protease activity;0.00324930446257139!GO:0045786;negative regulation of progression through cell cycle;0.0032954813504106!GO:0045454;cell redox homeostasis;0.00330432692315609!GO:0032940;secretion by cell;0.00330432692315609!GO:0009892;negative regulation of metabolic process;0.00337824544854678!GO:0043414;biopolymer methylation;0.00342759041934872!GO:0055029;nuclear DNA-directed RNA polymerase complex;0.0035286033256864!GO:0000428;DNA-directed RNA polymerase complex;0.0035286033256864!GO:0031324;negative regulation of cellular metabolic process;0.00356389108848752!GO:0022890;inorganic cation transmembrane transporter activity;0.00359444217545031!GO:0015980;energy derivation by oxidation of organic compounds;0.00362895841717668!GO:0045934;negative regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process;0.00368734340368967!GO:0006614;SRP-dependent cotranslational protein targeting to membrane;0.00370169170606346!GO:0045047;protein targeting to ER;0.00370169170606346!GO:0006695;cholesterol biosynthetic process;0.0038694707998954!GO:0008757;S-adenosylmethionine-dependent methyltransferase activity;0.00398661245996809!GO:0006611;protein export from nucleus;0.00401150417452066!GO:0032200;telomere organization and biogenesis;0.00408547302406959!GO:0000723;telomere maintenance;0.00408547302406959!GO:0048487;beta-tubulin binding;0.00424871178326444!GO:0016676;oxidoreductase activity, acting on heme group of donors, oxygen as acceptor;0.00432983062534802!GO:0015002;heme-copper terminal oxidase activity;0.00432983062534802!GO:0016675;oxidoreductase activity, acting on heme group of donors;0.00432983062534802!GO:0004129;cytochrome-c oxidase activity;0.00432983062534802!GO:0006144;purine base metabolic process;0.00437696414002779!GO:0046914;transition metal ion binding;0.00445469282979133!GO:0004298;threonine endopeptidase activity;0.00448812963411366!GO:0000118;histone deacetylase complex;0.004558885910731!GO:0030132;clathrin coat of coated pit;0.00457095552855047!GO:0000793;condensed chromosome;0.00457095552855047!GO:0008408;3'-5' exonuclease activity;0.00479231878334864!GO:0004221;ubiquitin thiolesterase activity;0.00483404062733!GO:0005663;DNA replication factor C complex;0.00496390476683793!GO:0006891;intra-Golgi vesicle-mediated transport;0.00504641162214288!GO:0003746;translation elongation factor activity;0.00513512808156085!GO:0006367;transcription initiation from RNA polymerase II promoter;0.00514168990569664!GO:0006595;polyamine metabolic process;0.00521802111070031!GO:0044450;microtubule organizing center part;0.00527893342983099!GO:0005885;Arp2/3 protein complex;0.00552418924262009!GO:0030521;androgen receptor signaling pathway;0.00563066285396826!GO:0051539;4 iron, 4 sulfur cluster binding;0.00569275579630525!GO:0019205;nucleobase, nucleoside, nucleotide kinase activity;0.00569275579630525!GO:0000178;exosome (RNase complex);0.00581503715045139!GO:0019899;enzyme binding;0.00589828905372914!GO:0030867;rough endoplasmic reticulum membrane;0.00596873948729591!GO:0016790;thiolester hydrolase activity;0.00616127484177696!GO:0009112;nucleobase metabolic process;0.00624284379937467!GO:0006406;mRNA export from nucleus;0.00641504486095739!GO:0006650;glycerophospholipid metabolic process;0.00676457037701205!GO:0008180;signalosome;0.00679162666308507!GO:0005669;transcription factor TFIID complex;0.0069050864074038!GO:0031570;DNA integrity checkpoint;0.0069050864074038!GO:0005521;lamin binding;0.00700895274502687!GO:0000082;G1/S transition of mitotic cell cycle;0.00701800171073258!GO:0005720;nuclear heterochromatin;0.00719318220970097!GO:0051128;regulation of cellular component organization and biogenesis;0.00720763540541492!GO:0006376;mRNA splice site selection;0.00727016065768064!GO:0000389;nuclear mRNA 3'-splice site recognition;0.00727016065768064!GO:0016796;exonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters;0.00733921038472307!GO:0043130;ubiquitin binding;0.00755972273609647!GO:0032182;small conjugating protein binding;0.00755972273609647!GO:0009116;nucleoside metabolic process;0.00794347585378688!GO:0030137;COPI-coated vesicle;0.00800514162983448!GO:0051246;regulation of protein metabolic process;0.00809331900375579!GO:0006497;protein amino acid lipidation;0.00845531858688168!GO:0043631;RNA polyadenylation;0.00918111044948663!GO:0006091;generation of precursor metabolites and energy;0.00928735036060232!GO:0016584;nucleosome positioning;0.00932098871972173!GO:0016272;prefoldin complex;0.00934523309070746!GO:0008287;protein serine/threonine phosphatase complex;0.00950446943620956!GO:0000209;protein polyubiquitination;0.00971708915327301!GO:0006505;GPI anchor metabolic process;0.0101557833770319!GO:0005832;chaperonin-containing T-complex;0.0101557833770319!GO:0030384;phosphoinositide metabolic process;0.0104657063229503!GO:0000726;non-recombinational repair;0.0108402158179598!GO:0018196;peptidyl-asparagine modification;0.0108449880235753!GO:0018279;protein amino acid N-linked glycosylation via asparagine;0.0108449880235753!GO:0005758;mitochondrial intermembrane space;0.0115119860239973!GO:0000781;chromosome, telomeric region;0.0116762433130743!GO:0044430;cytoskeletal part;0.0117001021916952!GO:0005869;dynactin complex;0.0118786439138447!GO:0032561;guanyl ribonucleotide binding;0.0118786439138447!GO:0019001;guanyl nucleotide binding;0.0118786439138447!GO:0006506;GPI anchor biosynthetic process;0.0121194527277174!GO:0042054;histone methyltransferase activity;0.0121444862601796!GO:0031970;organelle envelope lumen;0.0123051399376841!GO:0000152;nuclear ubiquitin ligase complex;0.0128445322805426!GO:0031577;spindle checkpoint;0.0128448729008699!GO:0005652;nuclear lamina;0.0129292619204146!GO:0003730;mRNA 3'-UTR binding;0.0130037806274548!GO:0004532;exoribonuclease activity;0.0130037806274548!GO:0016896;exoribonuclease activity, producing 5'-phosphomonoesters;0.0130037806274548!GO:0030663;COPI coated vesicle membrane;0.0131427345673634!GO:0030126;COPI vesicle coat;0.0131427345673634!GO:0016569;covalent chromatin modification;0.0132596762604619!GO:0016481;negative regulation of transcription;0.0138541205906807!GO:0051129;negative regulation of cellular component organization and biogenesis;0.0140621253634387!GO:0016281;eukaryotic translation initiation factor 4F complex;0.0142883396418911!GO:0000339;RNA cap binding;0.0143564517509807!GO:0051540;metal cluster binding;0.0145030306344569!GO:0051536;iron-sulfur cluster binding;0.0145030306344569!GO:0003887;DNA-directed DNA polymerase activity;0.0148585955184381!GO:0007004;telomere maintenance via telomerase;0.0152789191469823!GO:0030133;transport vesicle;0.0156032756815208!GO:0035267;NuA4 histone acetyltransferase complex;0.0163992797132959!GO:0030320;cellular monovalent inorganic anion homeostasis;0.0165828747921957!GO:0055083;monovalent inorganic anion homeostasis;0.0165828747921957!GO:0055064;chloride ion homeostasis;0.0165828747921957!GO:0030644;cellular chloride ion homeostasis;0.0165828747921957!GO:0016891;endoribonuclease activity, producing 5'-phosphomonoesters;0.0172294085880062!GO:0030119;AP-type membrane coat adaptor complex;0.0172540742412833!GO:0051252;regulation of RNA metabolic process;0.0174547311430863!GO:0030658;transport vesicle membrane;0.0176772957032785!GO:0006607;NLS-bearing substrate import into nucleus;0.0176772957032785!GO:0004523;ribonuclease H activity;0.0176825164454925!GO:0006892;post-Golgi vesicle-mediated transport;0.0177593753166238!GO:0033170;DNA-protein loading ATPase activity;0.0182467589113249!GO:0003689;DNA clamp loader activity;0.0182467589113249!GO:0031901;early endosome membrane;0.0182467589113249!GO:0016279;protein-lysine N-methyltransferase activity;0.0187491223216915!GO:0018024;histone-lysine N-methyltransferase activity;0.0187491223216915!GO:0016278;lysine N-methyltransferase activity;0.0187491223216915!GO:0006220;pyrimidine nucleotide metabolic process;0.0194784996272022!GO:0042770;DNA damage response, signal transduction;0.019746781441487!GO:0030705;cytoskeleton-dependent intracellular transport;0.0208595963763569!GO:0016862;intramolecular oxidoreductase activity, interconverting keto- and enol-groups;0.0214649992996918!GO:0006356;regulation of transcription from RNA polymerase I promoter;0.0215393188305777!GO:0043284;biopolymer biosynthetic process;0.0219297237946798!GO:0051789;response to protein stimulus;0.0222782931900232!GO:0006986;response to unfolded protein;0.0222782931900232!GO:0019843;rRNA binding;0.0228344910988518!GO:0005665;DNA-directed RNA polymerase II, core complex;0.0228786137275371!GO:0030518;steroid hormone receptor signaling pathway;0.0232655754716742!GO:0051297;centrosome organization and biogenesis;0.0232655754716742!GO:0031023;microtubule organizing center organization and biogenesis;0.0232655754716742!GO:0008213;protein amino acid alkylation;0.0232655754716742!GO:0006479;protein amino acid methylation;0.0232655754716742!GO:0030496;midbody;0.0233356831879355!GO:0030131;clathrin adaptor complex;0.0234472166068985!GO:0006301;postreplication repair;0.0234730852689583!GO:0008610;lipid biosynthetic process;0.023559760875276!GO:0005938;cell cortex;0.0235678151222375!GO:0046128;purine ribonucleoside metabolic process;0.0236244183106202!GO:0042278;purine nucleoside metabolic process;0.0236244183106202!GO:0008536;Ran GTPase binding;0.0236244183106202!GO:0016585;chromatin remodeling complex;0.0236754697364326!GO:0031371;ubiquitin conjugating enzyme complex;0.0238238775118538!GO:0043022;ribosome binding;0.0238466133229727!GO:0042158;lipoprotein biosynthetic process;0.024160498081303!GO:0030125;clathrin vesicle coat;0.0241799442045463!GO:0030665;clathrin coated vesicle membrane;0.0241799442045463!GO:0031252;leading edge;0.0247963865003246!GO:0000930;gamma-tubulin complex;0.0248489884997562!GO:0030027;lamellipodium;0.0255992637909766!GO:0007098;centrosome cycle;0.0262828943323008!GO:0000077;DNA damage checkpoint;0.0267358697320051!GO:0000123;histone acetyltransferase complex;0.0269208902463259!GO:0030176;integral to endoplasmic reticulum membrane;0.027623932457824!GO:0032981;mitochondrial respiratory chain complex I assembly;0.027705933304789!GO:0010257;NADH dehydrogenase complex assembly;0.027705933304789!GO:0033108;mitochondrial respiratory chain complex assembly;0.027705933304789!GO:0000805;X chromosome;0.0281587786867049!GO:0001740;Barr body;0.0281587786867049!GO:0043189;H4/H2A histone acetyltransferase complex;0.0281901327127656!GO:0006007;glucose catabolic process;0.0282686810776529!GO:0043624;cellular protein complex disassembly;0.0287636295360415!GO:0016893;endonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters;0.0293178359753591!GO:0007021;tubulin folding;0.0294317727456182!GO:0030660;Golgi-associated vesicle membrane;0.0294317727456182!GO:0016835;carbon-oxygen lyase activity;0.0294444235713568!GO:0006541;glutamine metabolic process;0.0297856805806512!GO:0008143;poly(A) binding;0.0299389275454014!GO:0019206;nucleoside kinase activity;0.0301168471155548!GO:0046966;thyroid hormone receptor binding;0.0303868920737712!GO:0051320;S phase;0.0306979118311706!GO:0016197;endosome transport;0.0310384664239096!GO:0005487;nucleocytoplasmic transporter activity;0.0310653916688135!GO:0005658;alpha DNA polymerase:primase complex;0.0313806088156026!GO:0000084;S phase of mitotic cell cycle;0.0319750794335111!GO:0050178;phenylpyruvate tautomerase activity;0.0320812822170288!GO:0042802;identical protein binding;0.0324723538574974!GO:0042769;DNA damage response, detection of DNA damage;0.032847972574729!GO:0051656;establishment of organelle localization;0.032847972574729!GO:0031902;late endosome membrane;0.0330507275479861!GO:0005784;translocon complex;0.0338384046690657!GO:0009124;nucleoside monophosphate biosynthetic process;0.034552332788305!GO:0009123;nucleoside monophosphate metabolic process;0.034552332788305!GO:0008097;5S rRNA binding;0.0345860240371819!GO:0005850;eukaryotic translation initiation factor 2 complex;0.0353584518961154!GO:0042026;protein refolding;0.0354355764910532!GO:0007007;inner mitochondrial membrane organization and biogenesis;0.0362518961144076!GO:0005680;anaphase-promoting complex;0.0363532066373744!GO:0007094;mitotic cell cycle spindle assembly checkpoint;0.0365338900335727!GO:0047485;protein N-terminus binding;0.0368641262701184!GO:0009303;rRNA transcription;0.0369413504875716!GO:0000086;G2/M transition of mitotic cell cycle;0.0381404652379227!GO:0060052;neurofilament cytoskeleton organization and biogenesis;0.0382394476920884!GO:0006275;regulation of DNA replication;0.0388517051664265!GO:0007019;microtubule depolymerization;0.0395377813796212!GO:0003725;double-stranded RNA binding;0.0397352840154307!GO:0033116;ER-Golgi intermediate compartment membrane;0.0422145254658436!GO:0000803;sex chromosome;0.0422145254658436!GO:0001739;sex chromatin;0.0422145254658436!GO:0030911;TPR domain binding;0.0424454775635073!GO:0001832;blastocyst growth;0.0432401040113543!GO:0006890;retrograde vesicle-mediated transport, Golgi to ER;0.0432401040113543!GO:0031625;ubiquitin protein ligase binding;0.043774427577422!GO:0016570;histone modification;0.0442625622432028!GO:0012501;programmed cell death;0.0455952629235973!GO:0030135;coated vesicle;0.0457478882900013!GO:0022406;membrane docking;0.0459691802589453!GO:0048278;vesicle docking;0.0459691802589453!GO:0005881;cytoplasmic microtubule;0.0468136687922108!GO:0046112;nucleobase biosynthetic process;0.0472362088147875!GO:0031111;negative regulation of microtubule polymerization or depolymerization;0.0479024951057463!GO:0032984;macromolecular complex disassembly;0.0493473552893445 | |||
|sample_id=10843 | |sample_id=10843 | ||
|sample_note= | |sample_note= | ||
| Line 76: | Line 102: | ||
|sample_tissue=skin | |sample_tissue=skin | ||
|top_motifs=POU6F1:3.69163208245;NANOG:3.43252468768;NKX2-3_NKX2-5:2.56793325908;BREu{core}:2.51708414314;E2F1..5:2.48277855737;ADNP_IRX_SIX_ZHX:2.41260920252;TFDP1:2.34113332559;POU1F1:2.33195720848;NFY{A,B,C}:2.25534329513;MYOD1:2.18330820554;LMO2:1.9945859458;NRF1:1.86164993992;FOXQ1:1.85369465812;POU3F1..4:1.832739856;STAT5{A,B}:1.80761012545;SOX{8,9,10}:1.76063104519;TEF:1.61473154478;FOXM1:1.49827732829;YY1:1.46985458834;PDX1:1.46263073569;AHR_ARNT_ARNT2:1.40189109822;ZNF143:1.39159341737;NKX6-1,2:1.33208690801;LHX3,4:1.32269402212;SNAI1..3:1.29741531829;PAX6:1.26872936126;GFI1:1.24716829116;ONECUT1,2:1.22256150421;RBPJ:1.19974040649;PITX1..3:1.16455861361;HOX{A4,D4}:1.14752157016;ZEB1:1.14185262997;DBP:1.12609536937;POU2F1..3:1.10951660327;EVI1:1.10206540895;HOXA9_MEIS1:1.03485472124;PAX5:1.00868094893;AIRE:0.904485228115;SOX17:0.896141473842;ELK1,4_GABP{A,B1}:0.886849016268;MYB:0.87820085342;PBX1:0.860623097114;FOXD3:0.857678563861;PAX3,7:0.85640443753;PAX1,9:0.849087117455;PRRX1,2:0.8405608227;SOX5:0.826235623061;ESRRA:0.805288339724;ZFP161:0.778514661543;RFX2..5_RFXANK_RFXAP:0.727611701886;RXR{A,B,G}_{NR1H2,PPAR}dimers:0.724771787614;FOXP1:0.720739933648;NR1H4:0.697678027345;NKX2-1,4:0.686895496604;STAT1,3:0.683906085104;ZIC1..3:0.65582987438;GFI1B:0.628234127961;CRX:0.621282947209;ZBTB16:0.589007631719;NR6A1:0.582087980533;MZF1:0.575862867338;PAX8:0.570939187466;TOPORS:0.547076360111;KLF4:0.530300631258;ZBTB6:0.528474576196;UFEwm:0.502596278628;ATF4:0.497286722444;CUX2:0.492544374796;TFAP2B:0.487499081143;FOXL1:0.474867689874;FOXA2:0.442888838341;T:0.424143001329;REST:0.412788223935;MED-1{core}:0.401912383665;POU5F1:0.391523424914;CDX1,2,4:0.380259874809;TGIF1:0.374704223085;RFX1:0.369237694384;ZNF423:0.359977715214;NKX3-1:0.35644105735;EGR1..3:0.344410105222;OCT4_SOX2{dimer}:0.332117342407;FOXN1:0.311673411438;IKZF2:0.304328769033;PATZ1:0.293290140159;AR:0.292555174406;BPTF:0.275271779862;HAND1,2:0.253119459542;TAL1_TCF{3,4,12}:0.248631548401;ZNF384:0.222083307506;PPARG:0.216384216243;PAX4:0.2087246761;FOX{F1,F2,J1}:0.207230844927;XCPE1{core}:0.187045218876;NR5A1,2:0.179260580794;RORA:0.160572289611;ATF5_CREB3:0.15825752657;NFE2L1:0.155532288417;bHLH_family:0.143560910587;RREB1:0.107448525189;HOX{A6,A7,B6,B7}:0.0997231882611;HES1:0.0827148223911;LEF1_TCF7_TCF7L1,2:0.0674961808387;NFIL3:0.0511862460966;GATA4:0.0425684405336;HIC1:-0.0220507915377;MTE{core}:-0.0294472423155;PRDM1:-0.0599985825726;MTF1:-0.063742058695;MYFfamily:-0.0955454881431;GCM1,2:-0.102015817227;SPZ1:-0.130499175357;FOXP3:-0.177410777725;GATA6:-0.190792206923;HNF1A:-0.206630220707;ARID5B:-0.212061601227;ALX4:-0.214255946104;HMGA1,2:-0.224641099568;HOX{A5,B5}:-0.226648033933;NKX2-2,8:-0.230024045396;HSF1,2:-0.267392211736;SOX2:-0.27650844262;GTF2I:-0.339677116029;CDC5L:-0.380377885599;CREB1:-0.391408417591;NKX3-2:-0.423242627251;RUNX1..3:-0.46519502175;MEF2{A,B,C,D}:-0.471929973614;TP53:-0.485997754669;JUN:-0.504525924393;FOX{D1,D2}:-0.513853996386;RXR{A,B,G}:-0.523039468748;EN1,2:-0.54971838345;ARNT_ARNT2_BHLHB2_MAX_MYC_USF1:-0.567401393503;SREBF1,2:-0.578381501717;HBP1_HMGB_SSRP1_UBTF:-0.589537066152;IKZF1:-0.620014490725;TBX4,5:-0.642945271182;TLX1..3_NFIC{dimer}:-0.649618931578;NFKB1_REL_RELA:-0.65557412781;SPI1:-0.661573826186;DMAP1_NCOR{1,2}_SMARC:-0.665613384798;FOSL2:-0.684667386975;BACH2:-0.719039352449;FOXO1,3,4:-0.738644518715;HNF4A_NR2F1,2:-0.738736369075;GTF2A1,2:-0.785479377996;SPIB:-0.787250681552;NHLH1,2:-0.8117037259;FOS_FOS{B,L1}_JUN{B,D}:-0.821391306078;NFE2:-0.846338861174;NFIX:-0.854119073543;EBF1:-0.90011783618;PAX2:-0.908875226257;VSX1,2:-0.937344140507;ATF2:-0.992242157196;NR3C1:-1.0238857301;GZF1:-1.02565281064;HLF:-1.0349672853;NFE2L2:-1.09392289637;TFAP4:-1.11364665967;ZNF238:-1.11556378552;TEAD1:-1.11600768648;MAZ:-1.1322347807;ELF1,2,4:-1.14655176582;SMAD1..7,9:-1.2120866795;ALX1:-1.21504339429;HIF1A:-1.23549079891;IRF7:-1.24288663631;FOX{I1,J2}:-1.24699367968;NANOG{mouse}:-1.26258521464;XBP1:-1.27223780793;ATF6:-1.31963784074;ETS1,2:-1.32012766887;ZNF148:-1.33538566283;ESR1:-1.34430594231;MYBL2:-1.35124791054;TBP:-1.37233202548;CEBPA,B_DDIT3:-1.3906986315;SP1:-1.4330699201;RXRA_VDR{dimer}:-1.43518741179;GLI1..3:-1.44918176028;IRF1,2:-1.47515891704;HMX1:-1.50719840339;NFATC1..3:-1.52037058798;TLX2:-1.54670504109;EP300:-1.58718072272;MAFB:-1.61332223309;TFCP2:-1.83709849028;TFAP2{A,C}:-1.90693881227;STAT2,4,6:-2.02758553786;SRF:-2.20502855927 | |top_motifs=POU6F1:3.69163208245;NANOG:3.43252468768;NKX2-3_NKX2-5:2.56793325908;BREu{core}:2.51708414314;E2F1..5:2.48277855737;ADNP_IRX_SIX_ZHX:2.41260920252;TFDP1:2.34113332559;POU1F1:2.33195720848;NFY{A,B,C}:2.25534329513;MYOD1:2.18330820554;LMO2:1.9945859458;NRF1:1.86164993992;FOXQ1:1.85369465812;POU3F1..4:1.832739856;STAT5{A,B}:1.80761012545;SOX{8,9,10}:1.76063104519;TEF:1.61473154478;FOXM1:1.49827732829;YY1:1.46985458834;PDX1:1.46263073569;AHR_ARNT_ARNT2:1.40189109822;ZNF143:1.39159341737;NKX6-1,2:1.33208690801;LHX3,4:1.32269402212;SNAI1..3:1.29741531829;PAX6:1.26872936126;GFI1:1.24716829116;ONECUT1,2:1.22256150421;RBPJ:1.19974040649;PITX1..3:1.16455861361;HOX{A4,D4}:1.14752157016;ZEB1:1.14185262997;DBP:1.12609536937;POU2F1..3:1.10951660327;EVI1:1.10206540895;HOXA9_MEIS1:1.03485472124;PAX5:1.00868094893;AIRE:0.904485228115;SOX17:0.896141473842;ELK1,4_GABP{A,B1}:0.886849016268;MYB:0.87820085342;PBX1:0.860623097114;FOXD3:0.857678563861;PAX3,7:0.85640443753;PAX1,9:0.849087117455;PRRX1,2:0.8405608227;SOX5:0.826235623061;ESRRA:0.805288339724;ZFP161:0.778514661543;RFX2..5_RFXANK_RFXAP:0.727611701886;RXR{A,B,G}_{NR1H2,PPAR}dimers:0.724771787614;FOXP1:0.720739933648;NR1H4:0.697678027345;NKX2-1,4:0.686895496604;STAT1,3:0.683906085104;ZIC1..3:0.65582987438;GFI1B:0.628234127961;CRX:0.621282947209;ZBTB16:0.589007631719;NR6A1:0.582087980533;MZF1:0.575862867338;PAX8:0.570939187466;TOPORS:0.547076360111;KLF4:0.530300631258;ZBTB6:0.528474576196;UFEwm:0.502596278628;ATF4:0.497286722444;CUX2:0.492544374796;TFAP2B:0.487499081143;FOXL1:0.474867689874;FOXA2:0.442888838341;T:0.424143001329;REST:0.412788223935;MED-1{core}:0.401912383665;POU5F1:0.391523424914;CDX1,2,4:0.380259874809;TGIF1:0.374704223085;RFX1:0.369237694384;ZNF423:0.359977715214;NKX3-1:0.35644105735;EGR1..3:0.344410105222;OCT4_SOX2{dimer}:0.332117342407;FOXN1:0.311673411438;IKZF2:0.304328769033;PATZ1:0.293290140159;AR:0.292555174406;BPTF:0.275271779862;HAND1,2:0.253119459542;TAL1_TCF{3,4,12}:0.248631548401;ZNF384:0.222083307506;PPARG:0.216384216243;PAX4:0.2087246761;FOX{F1,F2,J1}:0.207230844927;XCPE1{core}:0.187045218876;NR5A1,2:0.179260580794;RORA:0.160572289611;ATF5_CREB3:0.15825752657;NFE2L1:0.155532288417;bHLH_family:0.143560910587;RREB1:0.107448525189;HOX{A6,A7,B6,B7}:0.0997231882611;HES1:0.0827148223911;LEF1_TCF7_TCF7L1,2:0.0674961808387;NFIL3:0.0511862460966;GATA4:0.0425684405336;HIC1:-0.0220507915377;MTE{core}:-0.0294472423155;PRDM1:-0.0599985825726;MTF1:-0.063742058695;MYFfamily:-0.0955454881431;GCM1,2:-0.102015817227;SPZ1:-0.130499175357;FOXP3:-0.177410777725;GATA6:-0.190792206923;HNF1A:-0.206630220707;ARID5B:-0.212061601227;ALX4:-0.214255946104;HMGA1,2:-0.224641099568;HOX{A5,B5}:-0.226648033933;NKX2-2,8:-0.230024045396;HSF1,2:-0.267392211736;SOX2:-0.27650844262;GTF2I:-0.339677116029;CDC5L:-0.380377885599;CREB1:-0.391408417591;NKX3-2:-0.423242627251;RUNX1..3:-0.46519502175;MEF2{A,B,C,D}:-0.471929973614;TP53:-0.485997754669;JUN:-0.504525924393;FOX{D1,D2}:-0.513853996386;RXR{A,B,G}:-0.523039468748;EN1,2:-0.54971838345;ARNT_ARNT2_BHLHB2_MAX_MYC_USF1:-0.567401393503;SREBF1,2:-0.578381501717;HBP1_HMGB_SSRP1_UBTF:-0.589537066152;IKZF1:-0.620014490725;TBX4,5:-0.642945271182;TLX1..3_NFIC{dimer}:-0.649618931578;NFKB1_REL_RELA:-0.65557412781;SPI1:-0.661573826186;DMAP1_NCOR{1,2}_SMARC:-0.665613384798;FOSL2:-0.684667386975;BACH2:-0.719039352449;FOXO1,3,4:-0.738644518715;HNF4A_NR2F1,2:-0.738736369075;GTF2A1,2:-0.785479377996;SPIB:-0.787250681552;NHLH1,2:-0.8117037259;FOS_FOS{B,L1}_JUN{B,D}:-0.821391306078;NFE2:-0.846338861174;NFIX:-0.854119073543;EBF1:-0.90011783618;PAX2:-0.908875226257;VSX1,2:-0.937344140507;ATF2:-0.992242157196;NR3C1:-1.0238857301;GZF1:-1.02565281064;HLF:-1.0349672853;NFE2L2:-1.09392289637;TFAP4:-1.11364665967;ZNF238:-1.11556378552;TEAD1:-1.11600768648;MAZ:-1.1322347807;ELF1,2,4:-1.14655176582;SMAD1..7,9:-1.2120866795;ALX1:-1.21504339429;HIF1A:-1.23549079891;IRF7:-1.24288663631;FOX{I1,J2}:-1.24699367968;NANOG{mouse}:-1.26258521464;XBP1:-1.27223780793;ATF6:-1.31963784074;ETS1,2:-1.32012766887;ZNF148:-1.33538566283;ESR1:-1.34430594231;MYBL2:-1.35124791054;TBP:-1.37233202548;CEBPA,B_DDIT3:-1.3906986315;SP1:-1.4330699201;RXRA_VDR{dimer}:-1.43518741179;GLI1..3:-1.44918176028;IRF1,2:-1.47515891704;HMX1:-1.50719840339;NFATC1..3:-1.52037058798;TLX2:-1.54670504109;EP300:-1.58718072272;MAFB:-1.61332223309;TFCP2:-1.83709849028;TFAP2{A,C}:-1.90693881227;STAT2,4,6:-2.02758553786;SRF:-2.20502855927 | ||
|xref= | |||
|zenbu_report=https://fantom.gsc.riken.jp/zenbu/reports/#miRNA_expression_atlas_human;search_select_hide=table111:FF:10843-111E6;search_select_hide=table117:FF:10843-111E6 | |||
}} | }} | ||
Latest revision as of 15:09, 3 June 2020
| Name: | merkel cell carcinoma cell line:MKL-1 |
|---|---|
| Species: | Human (Homo sapiens) |
| Library ID: | CNhs12838 |
| Sample type: | cell lines |
| Genomic View: | UCSC |
| RefEX: | Specific genes |
| CAGEd-oPOSSUM: | link |
| ZENBU report : | link |
| Additional information | ||||||||||||||||||||||||||||
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Sample information
RNA information
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| Download raw sequence, BAM & CTSS | ||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
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| RNA-Seq Accession numbers | ||||||||||||||||||||||||||||||||
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Relative expression to median (log10)
Transcription factors with enriched expression in this sampleRanked list of transcription factor promoter expression in this sample relative to the median expression in the FANTOM5 collection is shown. Value is log10 transformed.
Co-expression clusters with enriched expression in this sampleRanked list of co-expression cluster expression in this sample relative to the median expression in the FANTOM5 collection is shown. Value is log10 transformed. <br>Analyst:NA <br><br>link to dataset.<br>data
Repeat families with enriched expression in this sample<b>Summary:</b>Ranked list of repeat family expression in this sample relative tothe median expression in the FANTOM5 collection is shown. Value is log10transformed.<br><b>Analyst:</b>NA<br><br>link to dataset.<br>data
TFBS(DNA)motifs over-represented in proximal region of promoters active in this sample
JASPAR motifs<b>Summary:</b>Association of JASPAR motif to the promoter expression in thissample. Pearson's correlation between the number of TFBSs estimated byusing the position-weight matrix for each promoter and its expression isexpressed as Z-score by taking the ones based on random position-weightmatrix, and the tail probability of the normal distribution correspondingto the Z-score is taken as the resulting P-value. Lower P-value indicatesmore (non-random) association of the motif to promoter expression<br><b>Analyst:</b> Michiel de Hoon <br><br><br>link to dataset.<br>data
library id: CNhs12838
FANTOM5 phase1 novel unique motifs<b>Summary:</b>Association of the 169 novel and unique motifs discovered in FANTOM5 phase1 in this sample. Among the de-novo motifs discovered by DMF, HOMER,ChIPMunk, and ScanAll, only novel motifs are selected after comparison with known motif sets, and their clustering based on MACRO-APE resulted in169 novel and unique motifs. Their association to the promoter expression is evaluated in the same way to the JASPAR motif above<br><b>Analyst:</b> Michiel de Hoon <br><br><br>link to dataset.<br>data
library id: CNhs12838
| Novel motif | Logo | P-value |
|---|---|---|
| 1 | 1 | 0.753 |
| 10 | 10 | 0.596 |
| 100 | 100 | 0.704 |
| 101 | 101 | 0.375 |
| 102 | 102 | 0.63 |
| 103 | 103 | 0.75 |
| 104 | 104 | 0.662 |
| 105 | 105 | 0.141 |
| 106 | 106 | 4.82172e-4 |
| 107 | 107 | 0.0119 |
| 108 | 108 | 0.979 |
| 109 | 109 | 0.0962 |
| 11 | 11 | 0.385 |
| 110 | 110 | 0.809 |
| 111 | 111 | 0.59 |
| 112 | 112 | 0.157 |
| 113 | 113 | 0.457 |
| 114 | 114 | 0.0985 |
| 115 | 115 | 0.118 |
| 116 | 116 | 0.738 |
| 117 | 117 | 0.765 |
| 118 | 118 | 0.455 |
| 119 | 119 | 0.346 |
| 12 | 12 | 0.543 |
| 120 | 120 | 0.798 |
| 121 | 121 | 0.466 |
| 122 | 122 | 0.844 |
| 123 | 123 | 0.156 |
| 124 | 124 | 0.351 |
| 125 | 125 | 0.144 |
| 126 | 126 | 0.288 |
| 127 | 127 | 0.199 |
| 128 | 128 | 0.0277 |
| 129 | 129 | 0.49 |
| 13 | 13 | 0.577 |
| 130 | 130 | 0.993 |
| 131 | 131 | 0.0848 |
| 132 | 132 | 0.549 |
| 133 | 133 | 0.06 |
| 134 | 134 | 0.568 |
| 135 | 135 | 0.00569 |
| 136 | 136 | 0.597 |
| 137 | 137 | 0.439 |
| 138 | 138 | 0.228 |
| 139 | 139 | 0.0351 |
| 14 | 14 | 0.304 |
| 140 | 140 | 0.923 |
| 141 | 141 | 0.753 |
| 142 | 142 | 0.74 |
| 143 | 143 | 0.147 |
| 144 | 144 | 0.185 |
| 145 | 145 | 0.308 |
| 146 | 146 | 0.748 |
| 147 | 147 | 0.704 |
| 148 | 148 | 0.169 |
| 149 | 149 | 0.0117 |
| 15 | 15 | 0.372 |
| 150 | 150 | 0.545 |
| 151 | 151 | 0.347 |
| 152 | 152 | 0.0102 |
| 153 | 153 | 0.104 |
| 154 | 154 | 0.849 |
| 155 | 155 | 0.473 |
| 156 | 156 | 0.702 |
| 157 | 157 | 0.668 |
| 158 | 158 | 0.544 |
| 159 | 159 | 0.328 |
| 16 | 16 | 0.261 |
| 160 | 160 | 0.45 |
| 161 | 161 | 0.978 |
| 162 | 162 | 0.783 |
| 163 | 163 | 0.275 |
| 164 | 164 | 0.239 |
| 165 | 165 | 0.49 |
| 166 | 166 | 0.602 |
| 167 | 167 | 0.326 |
| 168 | 168 | 0.0729 |
| 169 | 169 | 0.0248 |
| 17 | 17 | 0.305 |
| 18 | 18 | 0.281 |
| 19 | 19 | 0.0846 |
| 2 | 2 | 0.14 |
| 20 | 20 | 0.556 |
| 21 | 21 | 0.229 |
| 22 | 22 | 0.0605 |
| 23 | 23 | 0.00511 |
| 24 | 24 | 0.371 |
| 25 | 25 | 0.995 |
| 26 | 26 | 0.803 |
| 27 | 27 | 0.332 |
| 28 | 28 | 0.976 |
| 29 | 29 | 0.896 |
| 3 | 3 | 0.066 |
| 30 | 30 | 0.21 |
| 31 | 31 | 0.674 |
| 32 | 32 | 0.012 |
| 33 | 33 | 0.573 |
| 34 | 34 | 0.196 |
| 35 | 35 | 0.878 |
| 36 | 36 | 0.73 |
| 37 | 37 | 0.0605 |
| 38 | 38 | 0.739 |
| 39 | 39 | 0.257 |
| 4 | 4 | 0.304 |
| 40 | 40 | 0.188 |
| 41 | 41 | 0.213 |
| 42 | 42 | 0.185 |
| 43 | 43 | 0.168 |
| 44 | 44 | 0.83 |
| 45 | 45 | 0.23 |
| 46 | 46 | 0.751 |
| 47 | 47 | 0.904 |
| 48 | 48 | 0.716 |
| 49 | 49 | 0.419 |
| 5 | 5 | 0.087 |
| 50 | 50 | 0.148 |
| 51 | 51 | 0.419 |
| 52 | 52 | 0.162 |
| 53 | 53 | 0.362 |
| 54 | 54 | 0.133 |
| 55 | 55 | 0.108 |
| 56 | 56 | 0.49 |
| 57 | 57 | 0.837 |
| 58 | 58 | 0.345 |
| 59 | 59 | 0.0865 |
| 6 | 6 | 0.668 |
| 60 | 60 | 0.0155 |
| 61 | 61 | 0.58 |
| 62 | 62 | 0.205 |
| 63 | 63 | 0.16 |
| 64 | 64 | 0.847 |
| 65 | 65 | 0.207 |
| 66 | 66 | 0.119 |
| 67 | 67 | 0.747 |
| 68 | 68 | 0.886 |
| 69 | 69 | 0.455 |
| 7 | 7 | 0.408 |
| 70 | 70 | 0.26 |
| 71 | 71 | 0.313 |
| 72 | 72 | 0.221 |
| 73 | 73 | 0.0106 |
| 74 | 74 | 0.686 |
| 75 | 75 | 0.325 |
| 76 | 76 | 0.781 |
| 77 | 77 | 0.0634 |
| 78 | 78 | 0.943 |
| 79 | 79 | 0.206 |
| 8 | 8 | 0.552 |
| 80 | 80 | 0.0172 |
| 81 | 81 | 0.447 |
| 82 | 82 | 0.321 |
| 83 | 83 | 0.083 |
| 84 | 84 | 0.664 |
| 85 | 85 | 0.00732 |
| 86 | 86 | 0.384 |
| 87 | 87 | 0.785 |
| 88 | 88 | 0.839 |
| 89 | 89 | 0.0956 |
| 9 | 9 | 0.107 |
| 90 | 90 | 0.546 |
| 91 | 91 | 0.299 |
| 92 | 92 | 0.0987 |
| 93 | 93 | 0.239 |
| 94 | 94 | 0.301 |
| 95 | 95 | 0.223 |
| 96 | 96 | 0.204 |
| 97 | 97 | 0.917 |
| 98 | 98 | 0.905 |
| 99 | 99 | 0.619 |
de novo motifs identified by HOMER in promoters active in this sample<b>Summary:</b>The result of HOMER in this sample is shown.<br><b>Analyst:</b>NA <br>
library id: CNhs12838
FANTOM5 (FF) ontology
Direct parent terms
is_a relathionship
CL:0000242 Merkel cell
EFO:0002091 biological replicate
FF:0000210 human sample
FF:0100297 carcinoma cell line sample
Ancestor terms (non development)<b>Summary:</b>Connected ontology terms with is_a, part_of or located_in relationship <br><b>Analyst:</b> Hideya Kawaji<br><br>link to source data<br>data
CL: Cell type
0000000 (cell), 0000000 (cell)
0000003 (native cell)
0000548 (animal cell)
0000066 (epithelial cell)
0002371 (somatic cell)
0000076 (squamous epithelial cell)
0002319 (neural cell)
0000095 (neuron associated cell)
0000325 (stuff accumulating cell)
0000240 (stratified squamous epithelial cell)
0000311 (keratin accumulating cell)
0000079 (stratified epithelial cell)
0000123 (neuron associated cell (sensu Vertebrata))
0000312 (keratinocyte)
0000237 (keratinizing barrier epithelial cell)
0000362 (epidermal cell)
0002159 (general ecto-epithelial cell)
0000255 (eukaryotic cell)
0002077 (ecto-epithelial cell)
0000242 (Merkel cell)
DOID: Disease
4 (disease)
162 (cancer)
14566 (disease of cellular proliferation)
0050687 (cell type cancer)
305 (carcinoma)
UBERON: Anatomy
0000468 (multi-cellular organism)
0001003 (skin epidermis)
0002097 (skin of body)
0002199 (integument)
0000483 (epithelium)
0000479 (tissue)
0004121 (ectoderm-derived structure)
0000062 (organ)
0000061 (anatomical structure)
0000465 (material anatomical entity)
0000467 (anatomical system)
0001062 (anatomical entity)
0000480 (anatomical group)
0000119 (cell layer)
0003102 (surface structure)
0007376 (outer epithelium)
0010371 (ecto-epithelium)
0010317 (germ layer / neural crest derived structure)
0002416 (integumental system)
FF: FANTOM5
0000102 (sample by type)
0000003 (cell line sample)
0000210 (human sample)
0000101 (sample by species)
0000001 (sample)
0100297 (carcinoma cell line sample)
0101120 (epithelial cell line sample)
Ancestor terms (development)<b>Summary:</b>Connected ontology terms with develops_from, derives_from or preceded_by relationship <br><b>Analyst:</b> Hideya Kawaji <br><br>link to source data<br>data
CL:0000133 (neurectodermal cell)
CL:0000357 (stratified epithelial stem cell)
CL:0000114 (surface ectodermal cell)
CL:0000221 (ectodermal cell)
