FF:11387-118C1: Difference between revisions
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{{f5samples | {{f5samples | ||
| | |DRA_sample_Accession=CAGE@SAMD00005757 | ||
|DRA_sample_Accession_RNASeq=sRNA-Seq@SAMD00005757 | |||
|accession_numbers=CAGE;DRX008372;DRR009244;DRZ000669;DRZ002054;DRZ012019;DRZ013404 | |||
|accession_numbers_RNASeq=sRNA-Seq;DRX037169;DRR041535;DRZ007177 | |||
|ancestors_in_anatomy_facet= | |||
|ancestors_in_cell_lineage_facet=CL:0000000,CL:0000003,CL:0000988,CL:0000548,CL:0002371,CL:0000542,CL:0000219,CL:0000738,CL:0002087,CL:0002242,CL:0000255,CL:0000623 | |||
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|ancestors_in_cell_lineage_facet=CL:0000000,CL:0000003,CL: | |||
|ancestors_in_disease_facet= | |ancestors_in_disease_facet= | ||
| | |ancestors_in_ff_facet=FF:0000102,FF:0000210,FF:0000002,FF:0000101,FF:0000001,FF:0000119 | ||
|comment= | |||
|created_by= | |||
|creation_date= | |||
|data_phase=2 | |||
|datafreeze_phase=2 | |||
|def= | |||
|expression_enrichment_score=chr1:25256756..25256774,-!p1@RUNX3!2.49!555.21!RUNX3;;chr2:192015701..192015743,-!p1@STAT4!2.29!261.69!STAT4;;chr17:45810594..45810608,+!p1@TBX21!2.13!135.15!TBX21;;chr2:145271342..145271377,-!p5@ZEB2!2.00!98.82!ZEB2;;chr20:50159198..50159299,-!p1@NFATC2!1.98!136.69!NFATC2;;chr19:45971246..45971265,+!p1@FOSB!1.93!1456.31!FOSB;;chr2:157189180..157189290,-!p1@NR4A2!1.87!358.72!NR4A2;;chr9:117150254..117150271,-!p1@AKNA!1.84!180.96!AKNA;;chr7:50343634..50343717,+!p2@IKZF1!1.82!65.71!IKZF1;;chr2:68592406..68592424,+!p1@PLEK!1.80!61.48!PLEK;;chr2:192015677..192015691,-!p3@STAT4!1.75!55.19!STAT4;;chr6:106546808..106546833,+!p3@PRDM1!1.74!67.77!PRDM1;;chr16:85932760..85932775,+!p1@IRF8!1.74!53.90!IRF8;;chr15:60884706..60884743,-!p1@RORA!1.73!257.07!RORA;;chr19:54041669..54041697,+!p2@ZNF331!1.73!52.11!ZNF331;;chr14:75745523..75745537,+!p1@FOS!1.72!5814.07!FOS;;chr19:54058073..54058088,+!p1@ZNF331!1.71!50.70!ZNF331;;chr17:38020392..38020477,-!p1@IKZF3!1.67!46.20!IKZF3;;chr10:8096631..8096660,+!p1@GATA3!1.65!52.88!GATA3;;chr1:25291475..25291511,-!p2@RUNX3!1.65!44.02!RUNX3;;chr20:56195474..56195506,-!p1@ZBP1!1.65!43.25!ZBP1;;chr1:59249688..59249703,-!p3@JUN!1.64!245.91!JUN;;chr8:123793988..123794016,+!p1@ZHX2!1.64!73.16!ZHX2;;chr3:63953435..63953499,+!p1@ATXN7!1.64!42.61!ATXN7;;chr14:64971288..64971316,-!p2@ZBTB25!1.61!117.56!ZBTB25;;chr3:39195075..39195088,-!p1@CSRNP1!1.58!224.34!CSRNP1;;chr9:3525727..3525828,-!p2@RFX3!1.57!90.61!RFX3;;chr12:72056800..72056834,+!p1@THAP2!1.57!48.77!THAP2;;chr8:81397820..81397836,+!p2@ZBTB10!1.57!45.31!ZBTB10;;chr9:102584262..102584276,+!p1@NR4A3!1.56!76.24!NR4A3;;chr1:59249707..59249727,-!p1@JUN!1.55!1359.79!JUN;;chrX:106960285..106960299,-!p1@TSC22D3!1.55!874.40!TSC22D3;;chr5:133450365..133450444,+!p1@TCF7!1.55!152.86!TCF7;;chr10:8096772..8096787,+!p2@GATA3!1.55!40.81!GATA3;;chr5:133451294..133451310,+!p2@TCF7!1.55!34.65!TCF7;;chr2:231090433..231090469,+!p1@SP140!1.53!33.24!SP140;;chrY:21906594..21906622,-!p1@KDM5D!1.52!32.34!KDM5D;;chr2:192015750..192015793,-!p2@STAT4!1.50!41.07!STAT4;;chr4:57522166..57522260,-!p2@HOPX!1.50!34.78!HOPX;;chr10:35484053..35484076,+!p1@CREM!1.49!72.26!CREM;;chr8:81397876..81397898,+!p5@ZBTB10!1.49!35.17!ZBTB10;;chr10:3824332..3824425,-!p4@KLF6!1.48!46.08!KLF6;;chr19:16435625..16435682,+!p1@KLF2!1.47!874.27!KLF2;;chr14:75746722..75746777,+!p2@FOS!1.47!36.32!FOS;;chr1:151030536..151030549,+!p8@MLLT11!1.47!28.75!MLLT11;;chr2:145277640..145277771,-!p1@ZEB2!1.44!339.21!ZEB2;;chr6:391743..391759,+!p1@IRF4!1.43!25.80!IRF4;;chr8:67525443..67525459,-!p2@MYBL1!1.42!37.60!MYBL1;;chr8:81397846..81397860,+!p3@ZBTB10!1.42!31.44!ZBTB10;;chr14:35873947..35873965,-!p1@NFKBIA!1.41!1511.37!NFKBIA;;chr5:131826457..131826514,-!p1@IRF1!1.41!928.05!IRF1;;chr3:5020939..5020952,+!p2@BHLHE40!1.41!75.98!BHLHE40;;chr17:37934365..37934387,-!p2@IKZF3!1.41!24.77!IKZF3;;chr12:72056773..72056796,+!p3@THAP2!1.40!31.06!THAP2;;chr13:74707894..74707947,-!p6@KLF12!1.39!26.44!KLF12;;chr4:57522598..57522664,-!p3@HOPX!1.39!23.74!HOPX;;chr4:103422499..103422632,+!p1@NFKB1!1.38!459.21!NFKB1;;chr19:19729477..19729542,-!p1@PBX4!1.37!46.72!PBX4;;chr2:61108878..61108891,+!p5@REL!1.37!22.33!REL;;chrX:106960180..106960197,-!p2@TSC22D3!1.36!82.14!TSC22D3;;chr7:104654690..104654704,+!p2@MLL5!1.36!42.87!MLL5;;chr2:231090471..231090504,+!p2@SP140!1.35!21.18!SP140;;chrX:106960221..106960236,-!p3@TSC22D3!1.34!56.98!TSC22D3;;chr6:91006518..91006570,-!p1@BACH2!1.34!47.74!BACH2;;chr6:106546834..106546850,+!p4@PRDM1!1.34!21.05!PRDM1;;chr7:50343895..50343936,+!p5@IKZF1!1.34!20.66!IKZF1;;chr10:35416142..35416169,+!p3@CREM!1.32!52.36!CREM;;chr11:47400078..47400106,-!p1@SPI1!1.32!20.02!SPI1;;chr4:57522674..57522699,-!p5@HOPX!1.32!19.89!HOPX;;chr17:38497662..38497713,+!p4@RARA!1.31!22.59!RARA;;chr3:23986824..23986848,+!p2@NR1D2!1.30!103.70!NR1D2;;chr19:45972701..45972774,+!p2@FOSB!1.30!25.80!FOSB;;chr10:104154415..104154434,+!p5@NFKB2!1.30!19.12!NFKB2;;chr2:61108695..61108753,+!p1@REL!1.29!125.13!REL;;chr7:50344289..50344323,+!p1@IKZF1!1.29!18.61!IKZF1;;chr21:36421347..36421380,-!p8@RUNX1!1.29!18.61!RUNX1;;chr7:104654718..104654741,+!p3@MLL5!1.28!26.05!MLL5;;chr4:109087445..109087463,-!p1@LEF1!1.28!17.84!LEF1;;chr9:102584128..102584144,+!p3@NR4A3!1.27!33.11!NR4A3;;chr8:123793252..123793266,+!p10@ZHX2!1.27!17.71!ZHX2;;chr14:35874077..35874091,-!p8@NFKBIA!1.27!17.45!NFKBIA;;chr1:10754477..10754517,-!p1@CASZ1!1.26!28.24!CASZ1;;chr1:25256175..25256228,-!p5@RUNX3!1.26!17.33!RUNX3;;chr10:3827389..3827408,-!p1@KLF6!1.25!1258.28!KLF6;;chr17:7388010..7388017,-!p5@ZBTB4!1.25!28.11!ZBTB4;;chr11:113930425..113930471,+!p1@ZBTB16!1.25!23.87!ZBTB16;;chr2:208394817..208394834,+!p3@CREB1!1.24!65.45!CREB1;;chr3:18486354..18486377,-!p2@SATB1!1.24!20.28!SATB1;;chr2:68592394..68592405,+!p2@PLEK!1.24!16.56!PLEK;;chr6:106546731..106546755,+!p5@PRDM1!1.23!15.91!PRDM1;;chr19:47616992..47617011,-!p4@ZC3H4!1.22!33.50!ZC3H4;;chr19:12902289..12902307,+!p1@JUNB!1.21!3387.36!JUNB;;chr9:102584159..102584174,+!p2@NR4A3!1.21!27.59!NR4A3;;chr18:3449330..3449344,+!p10@TGIF1!1.21!20.28!TGIF1;;chr6:106546786..106546802,+!p6@PRDM1!1.21!15.27!PRDM1;;chr7:50344251..50344288,+!p3@IKZF1!1.21!15.27!IKZF1;;chr3:71542615..71542644,-!p12@FOXP1!1.21!15.14!FOXP1;;chr3:39195037..39195069,-!p2@CSRNP1!1.20!90.61!CSRNP1;;chr2:61108808..61108821,+!p3@REL!1.20!18.61!REL;;chr3:27763807..27763822,-!p1@EOMES!1.20!15.02!EOMES;;chr17:38020516..38020544,-!p5@IKZF3!1.20!15.02!IKZF3;;chr2:97202480..97202499,+!p1@ARID5A!1.19!146.31!ARID5A;;chr14:35872962..35873025,-!p3@NFKBIA!1.19!36.32!NFKBIA;;chr8:123794038..123794056,+!p5@ZHX2!1.19!14.50!ZHX2;;chr7:137620650..137620677,-!p3@CREB3L2!1.18!14.25!CREB3L2;;chr19:54041645..54041661,+!p5@ZNF331!1.18!14.25!ZNF331;;chr1:26697243..26697258,-!p1@ZNF683!1.18!14.12!ZNF683;;chr2:157189617..157189667,-!p4@NR4A2!1.18!14.12!NR4A2;;chr10:104154246..104154347,+!p3@NFKB2!1.17!84.58!NFKB2;;chr1:91487774..91487802,-!p2@ZNF644!1.16!35.17!ZNF644;;chr3:101546827..101546847,+!p2@NFKBIZ!1.16!18.99!NFKBIZ;;chr12:72056749..72056767,+!p6@THAP2!1.16!15.02!THAP2;;chr2:43453734..43453751,-!p1@ZFP36L2!1.15!1394.19!ZFP36L2;;chr10:3827371..3827386,-!p2@KLF6!1.15!109.86!KLF6;;chr9:102584241..102584261,+!p4@NR4A3!1.15!20.41!NR4A3;;chr1:37940170..37940190,+!p1@ZC3H12A!1.14!156.07!ZC3H12A;;chr1:59249645..59249656,-!p4@JUN!1.14!32.09!JUN;;chr14:99738138..99738163,-!p1@BCL11B!1.14!12.83!BCL11B;;chr7:99680193..99680204,-!p2@ZNF3!1.14!12.71!ZNF3;;chr8:102218439..102218455,-!p3@ZNF706!1.13!12.58!ZNF706;;chr4:38665769..38665801,+!p2@KLF3!1.12!108.71!KLF3;;chr7:106809470..106809481,+!p2@HBP1!1.12!17.33!HBP1;;chr1:25256439..25256476,-!p3@RUNX3!1.12!12.19!RUNX3;;chr6:91006575..91006602,-!p2@BACH2!1.11!17.58!BACH2;;chr4:109090075..109090095,-!p2@LEF1!1.11!11.94!LEF1;;chr4:57522513..57522548,-!p4@HOPX!1.11!11.81!HOPX;;chr19:18392422..18392440,-!p1@JUND!1.10!1604.42!JUND;;chr22:38597987..38598021,+!p2@MAFF!1.10!71.36!MAFF;;chr2:145275162..145275202,-!p2@ZEB2!1.10!69.05!ZEB2;;chr3:39195139..39195150,-!p3@CSRNP1!1.10!14.89!CSRNP1;;chr14:69262947..69262986,-!p3@ZFP36L1!1.10!14.25!ZFP36L1;;chr17:38020557..38020572,-!p4@IKZF3!1.10!11.55!IKZF3;;chr11:67007548..67007610,+!p3@KDM2A!1.09!83.94!KDM2A;;chr8:41909982..41910009,-!p2@KAT6A!1.09!12.83!KAT6A;;chr11:85375237..85375277,-!p4@CREBZF!1.08!12.83!CREBZF;;chr14:35872453..35872485,-!p2@NFKBIA!1.07!26.82!NFKBIA;;chr8:67525473..67525518,-!p1@MYBL1!1.07!25.03!MYBL1;;chr8:60031619..60031676,-!p1@TOX!1.07!23.36!TOX;;chr17:36861675..36861697,+!p3@MLLT6!1.06!24.64!MLLT6;;chr12:51158359..51158395,+!p4@ATF1!1.06!10.40!ATF1;;chr19:45504688..45504782,+!p1@RELB!1.05!62.76!RELB;;chr15:60884747..60884774,-!p3@RORA!1.05!25.16!RORA;;chr11:67007611..67007622,+!p6@KDM2A!1.05!13.86!KDM2A;;chr18:46475696..46475713,-!p1@SMAD7!1.05!11.42!SMAD7;;chr16:89789271..89789291,+!p5@ZNF276!1.05!10.27!ZNF276;;chr17:45810816..45810838,+!p2@TBX21!1.05!10.14!TBX21;;chr3:101568349..101568365,+!p1@NFKBIZ!1.04!522.36!NFKBIZ;;chr12:57914286..57914304,-!p1@DDIT3!1.04!363.47!DDIT3;;chrX:106960249..106960260,-!p5@TSC22D3!1.04!15.79!TSC22D3;;chr10:35484090..35484104,+!p6@CREM!1.04!10.01!CREM;;chr7:50344144..50344157,+!p6@IKZF1!1.04!9.88!IKZF1;;chr11:128392085..128392232,-!p1@ETS1!1.03!328.30!ETS1;;chr14:64971461..64971542,+!p1@ZBTB1!1.03!198.03!ZBTB1;;chr14:64971438..64971450,+!p2@ZBTB1!1.03!22.72!ZBTB1;;chr6:12009042..12009092,+!p6@HIVEP1!1.03!12.83!HIVEP1;;chr9:102584278..102584285,+!p5@NR4A3!1.03!9.75!NR4A3;;chr12:54778471..54778528,-!p1@ZNF385A!1.03!9.75!ZNF385A;;chr1:92951607..92951661,-!p1@GFI1!1.03!9.75!GFI1;;chr17:38497715..38497734,+!p8@RARA!1.03!9.63!RARA;;chr6:12011943..12012015,+!p2@HIVEP1!1.02!31.19!HIVEP1;;chr19:12721790..12721810,+!p2@ZNF791!1.02!26.44!ZNF791;;chr15:57211634..57211657,+!p5@TCF12!1.02!14.50!TCF12;;chr11:13299319..13299424,+!p1@ARNTL!1.01!95.87!ARNTL;;chr20:44600199..44600219,-!p3@ZNF335!1.01!12.58!ZNF335;;chr14:90085458..90085557,-!p1@FOXN3!1.00!96.64!FOXN3;;chr5:172483347..172483407,+!p1@C5orf41!1.00!69.31!CREBRF;;chr2:28616358..28616380,+!p3@FOSL2!1.00!47.87!FOSL2;;chr19:45252008..45252024,+!p2@BCL3!1.00!30.42!BCL3;;chr15:90544532..90544563,+!p1@ZNF710!1.00!18.35!ZNF710;;chr2:97203110..97203159,+!p4@ARID5A!1.00!8.98!ARID5A;;chr2:174828545..174828644,-!p1@SP3!0.99!137.84!SP3;;chr7:127032330..127032356,-!p3@ZNF800!0.99!11.29!ZNF800;;chr10:35416223..35416234,+!p12@CREM!0.99!8.86!CREM;;chr15:31619326..31619390,+!p2@KLF13!0.98!102.16!KLF13;;chr13:74708029..74708077,-!p2@KLF12!0.98!24.77!KLF12;;chr1:45805693..45805718,+!p3@TOE1!0.98!18.87!TOE1;;chr13:41593425..41593480,-!p1@ELF1!0.97!54.29!ELF1;;chr6:143266297..143266356,-!p1@HIVEP2!0.97!41.07!HIVEP2;;chr16:68119324..68119364,+!p1@NFATC3!0.97!38.50!NFATC3;;chr19:53289995..53290050,-!p1@ZNF600!0.97!35.29!ZNF600;;chr9:73028332..73028385,-!p3@KLF9!0.97!29.90!KLF9;;chr9:32550839..32550962,-!p3@TOPORS!0.97!21.18!TOPORS;;chr6:157098579..157098634,+!p4@ARID1B!0.97!18.99!ARID1B;;chr9:3526360..3526421,-!p5@RFX3!0.97!15.79!RFX3;;chr14:35872926..35872951,-!p4@NFKBIA!0.97!11.81!NFKBI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| |||
|fantom_cat=http://fantom.gsc.riken.jp/5/suppl/Hon_et_al_2016/vis/#/ontologies/CL:0000542;;http://fantom.gsc.riken.jp/5/suppl/Hon_et_al_2016/vis/#/ontologies/CL:0000623;;http://fantom.gsc.riken.jp/5/suppl/Hon_et_al_2016/vis/#/ontologies/CL:0000738;;http://fantom.gsc.riken.jp/5/suppl/Hon_et_al_2016/vis/#/ontologies/CL:0000988 | |||
|ffid_belonging_in_development=CL:0000134,CL:0000051 | |||
|fonse_cell_line= | |fonse_cell_line= | ||
|fonse_cell_line_closure= | |fonse_cell_line_closure= | ||
Line 66: | Line 43: | ||
|fonse_treatment= | |fonse_treatment= | ||
|fonse_treatment_closure= | |fonse_treatment_closure= | ||
|top_motifs= | |has_quality= | ||
|hg19bam=http://fantom.gsc.riken.jp/5/datafiles/latest/basic/human.primary_cell.hCAGE/Natural%2520Killer%2520Cells%252c%2520donor3.CNhs12001.11387-118C1.hg19.nobarcode.bam | |||
|hg19ctss=http://fantom.gsc.riken.jp/5/datafiles/latest/basic/human.primary_cell.hCAGE/Natural%2520Killer%2520Cells%252c%2520donor3.CNhs12001.11387-118C1.hg19.ctss.bed.gz | |||
|hg19fasta=http://fantom.gsc.riken.jp/5/datafiles/latest/basic/human.primary_cell.hCAGE/Natural%2520Killer%2520Cells%252c%2520donor3.CNhs12001.11387-118C1.hg19.nobarcode.rdna.fa.gz | |||
|hg38bam=http://fantom.gsc.riken.jp/5/datafiles/reprocessed/hg38_v2/basic/human.primary_cell.hCAGE/Natural%2520Killer%2520Cells%252c%2520donor3.CNhs12001.11387-118C1.hg38.nobarcode.bam | |||
|hg38ctss=http://fantom.gsc.riken.jp/5/datafiles/reprocessed/hg38_v2/basic/human.primary_cell.hCAGE/Natural%2520Killer%2520Cells%252c%2520donor3.CNhs12001.11387-118C1.hg38.nobarcode.ctss.bed.gz | |||
|id=FF:11387-118C1 | |||
|is_a=EFO:0002091;;FF:0000119 | |||
|is_obsolete= | |||
|library_id=CNhs12001 | |||
|library_id_phase_based=2:CNhs12001 | |||
|microRNAs= | |||
|microRNAs_nn= | |||
|microRNAs_nonnovel_cage=http://fantom.gsc.riken.jp/5/suppl/De_Rie_et_al_2017/vis_viewer/#/human#cage;sample;11387 | |||
|microRNAs_nonnovel_srna=http://fantom.gsc.riken.jp/5/suppl/De_Rie_et_al_2016/vis_viewer/#/human#srna;sample;SRhi10011.CAGATC.11387 | |||
|microRNAs_novel_cage=http://fantom.gsc.riken.jp/5/suppl/De_Rie_et_al_2017/vis_viewer_novel/#/human#cage;sample;11387 | |||
|microRNAs_novel_srna=http://fantom.gsc.riken.jp/5/suppl/De_Rie_et_al_2016/vis_viewer_novel/#/human#srna;sample;SRhi10011.CAGATC.11387 | |||
|name=Natural Killer Cells, donor3 | |||
|namespace=FANTOM5 | |||
|part_of= | |||
|profile_cagescan=,,, | |||
|profile_hcage=CNhs12001,LSID837,release011,COMPLETED | |||
|profile_rnaseq= | |||
|profile_srnaseq=SRhi10011,,, | |||
|refex=http://refex.dbcls.jp/genelist.php?lang | |||
|repeat_enrich_byfamily=0.052441152940763,0,0,0.0275745272549651,0,0,0.052441152940763,0.198269741488802,0.099226801963929,0.104974368557605,0.196954009982115,0,0,0,0.052441152940763,0,0,0,0,0,0,0.052441152940763,0.052441152940763,0,0.331473289799554,0,0,0,0,0.052441152940763,0.368189583541167,0,0,0.14543142229671,0,0,0,0,0,0.052441152940763,0,0,0,0.141458900963942,0.052441152940763,0,0.276194019457651,0.099226801963929,0.052441152940763,0,0,0,0,0,0,0.243970610334261,0,0,0,0.052441152940763,0,-0.0115273090448445,0,0.405684831714477,0,0,0.485122782875044,0,0.099226801963929,0,0,0,0,0.247987550655999,0,0,0,1.7385881915969,0,0,0.446661800390021,0,0,0,0,0,0,0,0.0175420109976594,0,0,0,0,0,0,0.0407799751521038,0.565090992901108,0.0496134009819645,0,0.283819195684492,0,0.707493203270024,0.103920949273096,0,0,0.0262205764703815,0,0,0.331076824682992,0,0,0,0,0,0,0.0262205764703815,0,0,0,0,-0.0701530174520795,0.052441152940763,0,0,0.119053920726158,0.148325824366776,0.099226801963929,0,0.141458900963942,0,0,0 | |||
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| |||
|rna_box=118 | |||
|rna_catalog_number=3H100-50-10 | |||
|rna_concentration=0.983 | |||
|rna_extraction_protocol=OP-RNA-extraction-totalRNA-TRIzol-isopropanol-v1.0 | |||
|rna_lot_number=NK727 | |||
|rna_od260/230= | |||
|rna_od260/280= | |||
|rna_position=C1 | |||
|rna_rin= | |||
|rna_sample_type=total RNA | |||
|rna_tube_id=118C1 | |||
|rna_weight_ug=10 | |||
|rnaseq_library_id=SRhi10011.CAGATC | |||
|sample_age=53 | |||
|sample_category=primary cells | |||
|sample_cell_catalog=N/A | |||
|sample_cell_line= | |||
|sample_cell_lot=N/A | |||
|sample_cell_type=natural killer cell | |||
|sample_collaboration=FANTOM5 OSC CORE (contact: Al Forrest) | |||
|sample_company=3HBiomedical | |||
|sample_description= | |||
|sample_dev_stage=53 years old adult | |||
|sample_disease= | |||
|sample_donor(cell lot)= | |||
|sample_ethnicity=C | |||
|sample_experimental_condition= | |||
|sample_gostat=GO:0044464;cell part;0!GO:0005622;intracellular;0!GO:0044424;intracellular part;1.76007578019509e-219!GO:0043227;membrane-bound organelle;6.25515051143049e-192!GO:0043231;intracellular membrane-bound organelle;1.4169582482272e-191!GO:0043226;organelle;1.58360636595624e-178!GO:0043229;intracellular organelle;8.22091210353835e-178!GO:0005737;cytoplasm;4.10817136979405e-124!GO:0005634;nucleus;1.17473176663397e-115!GO:0043170;macromolecule metabolic process;9.95168722124439e-104!GO:0044422;organelle part;1.04654641231597e-100!GO:0044446;intracellular organelle part;4.58967418260596e-99!GO:0044237;cellular metabolic process;1.77559300399843e-95!GO:0044238;primary metabolic process;9.60766514064356e-95!GO:0043283;biopolymer metabolic process;1.88577974436007e-80!GO:0044428;nuclear part;1.03960847333321e-77!GO:0032991;macromolecular complex;1.84542358894759e-77!GO:0044444;cytoplasmic part;3.25340438563892e-75!GO:0003723;RNA binding;1.23859298040982e-72!GO:0005515;protein binding;2.10762674713506e-70!GO:0010467;gene expression;8.17856280138567e-66!GO:0030529;ribonucleoprotein complex;2.9214207023142e-65!GO:0043233;organelle lumen;8.92457542784952e-61!GO:0031974;membrane-enclosed lumen;8.92457542784952e-61!GO:0006139;nucleobase, nucleoside, nucleotide and nucleic acid metabolic process;1.23331906986626e-58!GO:0031981;nuclear lumen;1.93577866056912e-49!GO:0019538;protein metabolic process;3.30145065599897e-49!GO:0033036;macromolecule localization;1.2458712756092e-47!GO:0044267;cellular protein metabolic process;3.63224478028143e-47!GO:0003676;nucleic acid binding;1.1241839260727e-46!GO:0044260;cellular macromolecule metabolic process;2.4368325130119e-46!GO:0015031;protein transport;5.66122985579258e-46!GO:0045184;establishment of protein localization;2.11453635687681e-44!GO:0008104;protein localization;1.05368327566405e-43!GO:0006396;RNA processing;1.55233498387935e-43!GO:0006412;translation;1.29774905350393e-42!GO:0016071;mRNA metabolic process;3.60456687931329e-41!GO:0016070;RNA metabolic process;6.39247910142234e-40!GO:0043234;protein complex;2.81914588849081e-39!GO:0008380;RNA splicing;1.2737503222013e-35!GO:0006397;mRNA processing;3.40774791292876e-34!GO:0031090;organelle membrane;9.53513167852992e-34!GO:0016043;cellular component organization and biogenesis;1.27464700827029e-33!GO:0046907;intracellular transport;1.84653456201669e-33!GO:0005840;ribosome;4.31984187625357e-33!GO:0005654;nucleoplasm;1.49649029566127e-32!GO:0009059;macromolecule biosynthetic process;3.02427286259594e-32!GO:0006886;intracellular protein transport;8.72672948894678e-32!GO:0005739;mitochondrion;3.21751661420467e-31!GO:0031967;organelle envelope;3.18537412913929e-30!GO:0031975;envelope;6.93898133691652e-30!GO:0005829;cytosol;1.84970398577024e-29!GO:0006259;DNA metabolic process;3.22791699134226e-29!GO:0003735;structural constituent of ribosome;4.78843174997983e-29!GO:0000166;nucleotide binding;1.35436165769897e-28!GO:0033279;ribosomal subunit;2.78966538861547e-27!GO:0044451;nucleoplasm part;6.09108388106829e-27!GO:0006512;ubiquitin cycle;6.18420707513822e-27!GO:0005681;spliceosome;1.01880571247316e-26!GO:0065003;macromolecular complex assembly;1.11534925110637e-26!GO:0050794;regulation of cellular process;1.47953139944052e-26!GO:0043412;biopolymer modification;2.14600167769693e-26!GO:0012501;programmed cell death;5.5311992518863e-26!GO:0005830;cytosolic ribosome (sensu Eukaryota);6.39800809490334e-26!GO:0006915;apoptosis;7.52547137618269e-26!GO:0051641;cellular localization;2.88514955506042e-25!GO:0051649;establishment of cellular localization;3.65764653498984e-25!GO:0008219;cell death;4.72753524084388e-25!GO:0016265;death;4.72753524084388e-25!GO:0044429;mitochondrial part;3.05030954352936e-24!GO:0022607;cellular component assembly;5.85093569685724e-24!GO:0006464;protein modification process;6.94723440006058e-24!GO:0006996;organelle organization and biogenesis;9.54025578819116e-24!GO:0009058;biosynthetic process;1.15787397132328e-23!GO:0043687;post-translational protein modification;4.79890637900345e-23!GO:0008134;transcription factor binding;5.18184841309555e-23!GO:0022613;ribonucleoprotein complex biogenesis and assembly;6.72121636751711e-23!GO:0044249;cellular biosynthetic process;1.0511561569845e-22!GO:0044445;cytosolic part;9.97740093397019e-22!GO:0032553;ribonucleotide binding;1.03833933698833e-20!GO:0032555;purine ribonucleotide binding;1.03833933698833e-20!GO:0019222;regulation of metabolic process;2.46326319915824e-20!GO:0050789;regulation of biological process;4.80360743817642e-20!GO:0019941;modification-dependent protein catabolic process;8.57106307274517e-20!GO:0043632;modification-dependent macromolecule catabolic process;8.57106307274517e-20!GO:0051603;proteolysis involved in cellular protein catabolic process;9.22074401278528e-20!GO:0006511;ubiquitin-dependent protein catabolic process;1.10521377968663e-19!GO:0017076;purine nucleotide binding;1.13449241335568e-19!GO:0044257;cellular protein catabolic process;2.92404604717314e-19!GO:0044265;cellular macromolecule catabolic process;4.22162217843105e-19!GO:0017111;nucleoside-triphosphatase activity;6.48545418275625e-19!GO:0016462;pyrophosphatase activity;1.31585024218654e-18!GO:0006605;protein targeting;1.47815935136406e-18!GO:0016818;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides;1.57440337684894e-18!GO:0016817;hydrolase activity, acting on acid anhydrides;2.09409617875381e-18!GO:0016874;ligase activity;2.96332319419799e-18!GO:0006913;nucleocytoplasmic transport;3.69842371957146e-18!GO:0016604;nuclear body;5.19381150150989e-18!GO:0042981;regulation of apoptosis;5.44316390439969e-18!GO:0051169;nuclear transport;7.90838540904559e-18!GO:0043067;regulation of programmed cell death;9.95585006313906e-18!GO:0031323;regulation of cellular metabolic process;2.95949051660165e-17!GO:0007049;cell cycle;3.08584725507929e-17!GO:0005740;mitochondrial envelope;8.22362739175745e-17!GO:0043285;biopolymer catabolic process;1.03036044025132e-16!GO:0005524;ATP binding;1.10398228898016e-16!GO:0005730;nucleolus;1.63606732904281e-16!GO:0022618;protein-RNA complex assembly;1.901755678086e-16!GO:0031966;mitochondrial membrane;2.09455672330233e-16!GO:0006325;establishment and/or maintenance of chromatin architecture;2.47494998569088e-16!GO:0032559;adenyl ribonucleotide binding;3.87405286306872e-16!GO:0006350;transcription;9.98623629107459e-16!GO:0019866;organelle inner membrane;1.38141321150591e-15!GO:0006323;DNA packaging;1.56456703379219e-15!GO:0051276;chromosome organization and biogenesis;2.11844091483781e-15!GO:0043228;non-membrane-bound organelle;3.84953284598869e-15!GO:0043232;intracellular non-membrane-bound organelle;3.84953284598869e-15!GO:0016607;nuclear speck;3.91437164831682e-15!GO:0030554;adenyl nucleotide binding;5.02176416711023e-15!GO:0010468;regulation of gene expression;5.52733510752595e-15!GO:0005635;nuclear envelope;9.60951324589674e-15!GO:0006974;response to DNA damage stimulus;1.9948027950469e-14!GO:0008135;translation factor activity, nucleic acid binding;2.29565832220979e-14!GO:0006119;oxidative phosphorylation;2.58131898694204e-14!GO:0015934;large ribosomal subunit;2.99226167438833e-14!GO:0003712;transcription cofactor activity;3.16662930216553e-14!GO:0012505;endomembrane system;4.54536900105483e-14!GO:0015935;small ribosomal subunit;4.55108436230148e-14!GO:0009057;macromolecule catabolic process;4.78732758306849e-14!GO:0030163;protein catabolic process;6.59352569930765e-14!GO:0048523;negative regulation of cellular process;6.59453976916558e-14!GO:0031965;nuclear membrane;6.76085711772201e-14!GO:0006793;phosphorus metabolic process;6.78325043393423e-14!GO:0006796;phosphate metabolic process;6.78325043393423e-14!GO:0019219;regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process;7.45978371522587e-14!GO:0065007;biological regulation;8.66631133624221e-14!GO:0006366;transcription from RNA polymerase II promoter;1.55200005824052e-13!GO:0005843;cytosolic small ribosomal subunit (sensu Eukaryota);1.57354015535776e-13!GO:0005743;mitochondrial inner membrane;2.92005676188234e-13!GO:0005842;cytosolic large ribosomal subunit (sensu Eukaryota);4.69930772484009e-13!GO:0017038;protein import;7.29875349135322e-13!GO:0000398;nuclear mRNA splicing, via spliceosome;8.85896321453574e-13!GO:0000375;RNA splicing, via transesterification reactions;8.85896321453574e-13!GO:0000377;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile;8.85896321453574e-13!GO:0032774;RNA biosynthetic process;1.34220468082334e-12!GO:0006351;transcription, DNA-dependent;1.40557583993611e-12!GO:0007243;protein kinase cascade;2.35813285810042e-12!GO:0045449;regulation of transcription;3.0207938441592e-12!GO:0005794;Golgi apparatus;3.1221267708279e-12!GO:0016568;chromatin modification;3.36538406453212e-12!GO:0048770;pigment granule;4.03290434953656e-12!GO:0042470;melanosome;4.03290434953656e-12!GO:0048519;negative regulation of biological process;4.42538763617971e-12!GO:0042623;ATPase activity, coupled;4.42538763617971e-12!GO:0004386;helicase activity;5.27012657571779e-12!GO:0051726;regulation of cell cycle;6.08663855378773e-12!GO:0044453;nuclear membrane part;6.24259350089494e-12!GO:0022402;cell cycle process;6.32834677556459e-12!GO:0044455;mitochondrial membrane part;1.17372493612651e-11!GO:0000074;regulation of progression through cell cycle;1.217903938948e-11!GO:0008639;small protein conjugating enzyme activity;1.28091924427968e-11!GO:0016310;phosphorylation;1.29866298940272e-11!GO:0016887;ATPase activity;1.47676277337953e-11!GO:0000502;proteasome complex (sensu Eukaryota);1.66470396460805e-11!GO:0016192;vesicle-mediated transport;1.67174419886233e-11!GO:0004842;ubiquitin-protein ligase activity;1.67174419886233e-11!GO:0006281;DNA repair;1.95498501108092e-11!GO:0031324;negative regulation of cellular metabolic process;2.7466823265636e-11!GO:0006457;protein folding;3.00450693096526e-11!GO:0044248;cellular catabolic process;3.62047367042583e-11!GO:0008270;zinc ion binding;4.18429665337508e-11!GO:0019787;small conjugating protein ligase activity;4.54432930353012e-11!GO:0007249;I-kappaB kinase/NF-kappaB cascade;4.60747000249915e-11!GO:0007242;intracellular signaling cascade;5.53819482724246e-11!GO:0003743;translation initiation factor activity;6.37658146206599e-11!GO:0006606;protein import into nucleus;6.52663415347394e-11!GO:0051170;nuclear import;7.28386709589547e-11!GO:0048193;Golgi vesicle transport;1.2646558107219e-10!GO:0006355;regulation of transcription, DNA-dependent;1.54241478747247e-10!GO:0043122;regulation of I-kappaB kinase/NF-kappaB cascade;1.54241478747247e-10!GO:0050657;nucleic acid transport;1.7847118679355e-10!GO:0051236;establishment of RNA localization;1.7847118679355e-10!GO:0050658;RNA transport;1.7847118679355e-10!GO:0006413;translational initiation;1.88326158279323e-10!GO:0008026;ATP-dependent helicase activity;2.47835290743775e-10!GO:0006403;RNA localization;2.51666382869488e-10!GO:0005643;nuclear pore;2.57857639129269e-10!GO:0005768;endosome;2.85271531816817e-10!GO:0016564;transcription repressor activity;3.5895060743011e-10!GO:0006446;regulation of translational initiation;3.90377566793171e-10!GO:0005694;chromosome;4.0193813816918e-10!GO:0051246;regulation of protein metabolic process;5.56045530444517e-10!GO:0045934;negative regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process;6.28724745158144e-10!GO:0005746;mitochondrial respiratory chain;6.41627534849814e-10!GO:0006333;chromatin assembly or disassembly;6.56304401905419e-10!GO:0065004;protein-DNA complex assembly;6.9313121023728e-10!GO:0065009;regulation of a molecular function;1.09690934878629e-09!GO:0031980;mitochondrial lumen;1.19283412423959e-09!GO:0005759;mitochondrial matrix;1.19283412423959e-09!GO:0009892;negative regulation of metabolic process;1.79948679492352e-09!GO:0016481;negative regulation of transcription;1.97384812089497e-09!GO:0043123;positive regulation of I-kappaB kinase/NF-kappaB cascade;2.44690823806214e-09!GO:0016879;ligase activity, forming carbon-nitrogen bonds;3.01954769688379e-09!GO:0016881;acid-amino acid ligase activity;3.34665590296763e-09!GO:0016563;transcription activator activity;4.73014512801859e-09!GO:0050136;NADH dehydrogenase (quinone) activity;5.20403603916229e-09!GO:0003954;NADH dehydrogenase activity;5.20403603916229e-09!GO:0008137;NADH dehydrogenase (ubiquinone) activity;5.20403603916229e-09!GO:0016772;transferase activity, transferring phosphorus-containing groups;7.23764629704259e-09!GO:0006917;induction of apoptosis;7.37447946549315e-09!GO:0043065;positive regulation of apoptosis;7.50053408771751e-09!GO:0009719;response to endogenous stimulus;8.12710230338812e-09!GO:0003713;transcription coactivator activity;8.1605660933627e-09!GO:0051082;unfolded protein binding;8.41378008594229e-09!GO:0045786;negative regulation of progression through cell cycle;9.72109629156785e-09!GO:0051028;mRNA transport;1.00490037887896e-08!GO:0043068;positive regulation of programmed cell death;1.18807168925065e-08!GO:0003677;DNA binding;1.33072485235281e-08!GO:0012502;induction of programmed cell death;1.34823070928871e-08!GO:0044427;chromosomal part;1.46530600228373e-08!GO:0043069;negative regulation of programmed cell death;1.60907493317988e-08!GO:0016591;DNA-directed RNA polymerase II, holoenzyme;1.99556782575532e-08!GO:0043066;negative regulation of apoptosis;2.37702518193215e-08!GO:0016655;oxidoreductase activity, acting on NADH or NADPH, quinone or similar compound as acceptor;2.56160075206556e-08!GO:0046930;pore complex;3.05032446510551e-08!GO:0008565;protein transporter activity;3.46630118302216e-08!GO:0043566;structure-specific DNA binding;3.63531765834802e-08!GO:0016740;transferase activity;5.14803703435701e-08!GO:0065002;intracellular protein transport across a membrane;5.53447680006989e-08!GO:0042775;organelle ATP synthesis coupled electron transport;5.76378486300999e-08!GO:0042773;ATP synthesis coupled electron transport;5.76378486300999e-08!GO:0003697;single-stranded DNA binding;8.0153757422038e-08!GO:0042254;ribosome biogenesis and assembly;8.0576340598147e-08!GO:0019829;cation-transporting ATPase activity;8.51204234373421e-08!GO:0000785;chromatin;9.54583293339438e-08!GO:0015931;nucleobase, nucleoside, nucleotide and nucleic acid transport;1.01534755344647e-07!GO:0019899;enzyme binding;1.02245674633781e-07!GO:0030964;NADH dehydrogenase complex (quinone);1.25079895407868e-07!GO:0045271;respiratory chain complex I;1.25079895407868e-07!GO:0005747;mitochondrial respiratory chain complex I;1.25079895407868e-07!GO:0006916;anti-apoptosis;1.25309558700851e-07!GO:0032446;protein modification by small protein conjugation;1.47548189985715e-07!GO:0048522;positive regulation of cellular process;1.59115285308461e-07!GO:0046914;transition metal ion binding;1.82191954573196e-07!GO:0004674;protein serine/threonine kinase activity;1.90336207756349e-07!GO:0046961;hydrogen ion transporting ATPase activity, rotational mechanism;2.2019878989137e-07!GO:0006120;mitochondrial electron transport, NADH to ubiquinone;2.49526591839195e-07!GO:0016567;protein ubiquitination;2.64646416734198e-07!GO:0006357;regulation of transcription from RNA polymerase II promoter;2.88359963471315e-07!GO:0016787;hydrolase activity;4.9421927828347e-07!GO:0003924;GTPase activity;7.3377325448916e-07!GO:0046933;hydrogen ion transporting ATP synthase activity, rotational mechanism;8.10941466556082e-07!GO:0007264;small GTPase mediated signal transduction;1.27821865072396e-06!GO:0000151;ubiquitin ligase complex;1.33054849044475e-06!GO:0005773;vacuole;1.5555031545953e-06!GO:0005525;GTP binding;1.58063432572528e-06!GO:0006417;regulation of translation;1.63436059070917e-06!GO:0005783;endoplasmic reticulum;1.95377164029433e-06!GO:0044432;endoplasmic reticulum part;2.02519261318796e-06!GO:0030532;small nuclear ribonucleoprotein complex;2.0589910805691e-06!GO:0003714;transcription corepressor activity;2.17737781727559e-06!GO:0044440;endosomal part;2.81771799152785e-06!GO:0010008;endosome membrane;2.81771799152785e-06!GO:0050790;regulation of catalytic activity;3.20271206631888e-06!GO:0051168;nuclear export;3.33746969691855e-06!GO:0031497;chromatin assembly;3.61174981646008e-06!GO:0006260;DNA replication;4.40997851774318e-06!GO:0000278;mitotic cell cycle;4.44399955278914e-06!GO:0006888;ER to Golgi vesicle-mediated transport;5.31736296289523e-06!GO:0006334;nucleosome assembly;5.33867836047501e-06!GO:0051186;cofactor metabolic process;5.41724624972595e-06!GO:0048518;positive regulation of biological process;5.74029996782467e-06!GO:0005839;proteasome core complex (sensu Eukaryota);5.76430463823274e-06!GO:0003724;RNA helicase activity;5.91752391235748e-06!GO:0015986;ATP synthesis coupled proton transport;6.45916550528457e-06!GO:0015985;energy coupled proton transport, down electrochemical gradient;6.45916550528457e-06!GO:0005793;ER-Golgi intermediate compartment;6.58545585100955e-06!GO:0045892;negative regulation of transcription, DNA-dependent;6.80069655347071e-06!GO:0008632;apoptotic program;7.07050731179874e-06!GO:0009259;ribonucleotide metabolic process;7.97322550168382e-06!GO:0031202;RNA splicing factor activity, transesterification mechanism;8.12390323062953e-06!GO:0042110;T cell activation;8.31985849251064e-06!GO:0060090;molecular adaptor activity;9.22484840312936e-06!GO:0000323;lytic vacuole;9.22484840312936e-06!GO:0005764;lysosome;9.22484840312936e-06!GO:0006461;protein complex assembly;9.22484840312936e-06!GO:0009056;catabolic process;9.29774970316377e-06!GO:0006401;RNA catabolic process;9.81189391440045e-06!GO:0009967;positive regulation of signal transduction;1.0411791045202e-05!GO:0016651;oxidoreductase activity, acting on NADH or NADPH;1.05388334868735e-05!GO:0009260;ribonucleotide biosynthetic process;1.16707281016592e-05!GO:0009966;regulation of signal transduction;1.22208352178543e-05!GO:0016072;rRNA metabolic process;1.26964249936923e-05!GO:0000245;spliceosome assembly;1.26964249936923e-05!GO:0044431;Golgi apparatus part;1.27207329066734e-05!GO:0031326;regulation of cellular biosynthetic process;1.37884607727449e-05!GO:0006364;rRNA processing;1.38090740747272e-05!GO:0048475;coated membrane;1.38608687871301e-05!GO:0030117;membrane coat;1.38608687871301e-05!GO:0005770;late endosome;1.45795327950422e-05!GO:0009615;response to virus;1.49571251070032e-05!GO:0030120;vesicle coat;1.54326798125386e-05!GO:0030662;coated vesicle membrane;1.54326798125386e-05!GO:0009152;purine ribonucleotide biosynthetic process;1.54383503040739e-05!GO:0004298;threonine endopeptidase activity;1.61510207891013e-05!GO:0009060;aerobic respiration;1.82972131546584e-05!GO:0046649;lymphocyte activation;1.8787265810485e-05!GO:0016363;nuclear matrix;1.92304979969289e-05!GO:0005813;centrosome;2.45108131057757e-05!GO:0006164;purine nucleotide biosynthetic process;2.45267441480377e-05!GO:0009150;purine ribonucleotide metabolic process;2.45267441480377e-05!GO:0042175;nuclear envelope-endoplasmic reticulum network;2.50737377608842e-05!GO:0015078;hydrogen ion transmembrane transporter activity;2.52561361663378e-05!GO:0006399;tRNA metabolic process;2.60643554078657e-05!GO:0005761;mitochondrial ribosome;2.69106194561558e-05!GO:0000313;organellar ribosome;2.69106194561558e-05!GO:0032561;guanyl ribonucleotide binding;2.69106194561558e-05!GO:0019001;guanyl nucleotide binding;2.69106194561558e-05!GO:0016469;proton-transporting two-sector ATPase complex;2.6988164410742e-05!GO:0006402;mRNA catabolic process;2.78727663617814e-05!GO:0007265;Ras protein signal transduction;3.1541463849149e-05!GO:0009889;regulation of biosynthetic process;3.3880905729831e-05!GO:0006163;purine nucleotide metabolic process;3.46005149424316e-05!GO:0005789;endoplasmic reticulum membrane;3.49612275154474e-05!GO:0045321;leukocyte activation;4.52059296879526e-05!GO:0016301;kinase activity;4.80385908774228e-05!GO:0006754;ATP biosynthetic process;4.83701209005927e-05!GO:0006753;nucleoside phosphate metabolic process;4.83701209005927e-05!GO:0016197;endosome transport;5.36689085636061e-05!GO:0008234;cysteine-type peptidase activity;5.46021893062431e-05!GO:0045259;proton-transporting ATP synthase complex;5.46564980566659e-05!GO:0006732;coenzyme metabolic process;5.72396717861973e-05!GO:0015405;P-P-bond-hydrolysis-driven transmembrane transporter activity;6.07760721146506e-05!GO:0015399;primary active transmembrane transporter activity;6.07760721146506e-05!GO:0009142;nucleoside triphosphate biosynthetic process;6.07760721146506e-05!GO:0009201;ribonucleoside triphosphate biosynthetic process;6.07760721146506e-05!GO:0002376;immune system process;7.35735490269564e-05!GO:0005815;microtubule organizing center;7.49128389194323e-05!GO:0042625;ATPase activity, coupled to transmembrane movement of ions;7.90028583576672e-05!GO:0048468;cell development;8.00227244421586e-05!GO:0008186;RNA-dependent ATPase activity;8.3088262006719e-05!GO:0030695;GTPase regulator activity;8.56599154061606e-05!GO:0006613;cotranslational protein targeting to membrane;8.73473670548115e-05!GO:0016773;phosphotransferase activity, alcohol group as acceptor;0.000100663257597067!GO:0005769;early endosome;0.000105701689594327!GO:0016779;nucleotidyltransferase activity;0.000112193922301365!GO:0009199;ribonucleoside triphosphate metabolic process;0.000112625858651789!GO:0009206;purine ribonucleoside triphosphate biosynthetic process;0.00011317601319448!GO:0009145;purine nucleoside triphosphate biosynthetic process;0.00011317601319448!GO:0046034;ATP metabolic process;0.000134048505078374!GO:0001772;immunological synapse;0.000149630116375711!GO:0003729;mRNA binding;0.000150604564275022!GO:0007005;mitochondrion organization and biogenesis;0.000150842237536892!GO:0016876;ligase activity, forming aminoacyl-tRNA and related compounds;0.000163176845846563!GO:0004812;aminoacyl-tRNA ligase activity;0.000163176845846563!GO:0016875;ligase activity, forming carbon-oxygen bonds;0.000163176845846563!GO:0051427;hormone receptor binding;0.000165401317453868!GO:0045333;cellular respiration;0.00019370912787863!GO:0009141;nucleoside triphosphate metabolic process;0.000197615222025165!GO:0009205;purine ribonucleoside triphosphate metabolic process;0.00020196943911925!GO:0009144;purine nucleoside triphosphate metabolic process;0.00020196943911925!GO:0043623;cellular protein complex assembly;0.000202003154379954!GO:0005070;SH3/SH2 adaptor activity;0.000202003154379954!GO:0008047;enzyme activator activity;0.000211663859374437!GO:0006352;transcription initiation;0.000234544790203195!GO:0030530;heterogeneous nuclear ribonucleoprotein complex;0.000235383748747759!GO:0004004;ATP-dependent RNA helicase activity;0.000255238390298669!GO:0005667;transcription factor complex;0.000258304847583769!GO:0000139;Golgi membrane;0.000296903169010688!GO:0035257;nuclear hormone receptor binding;0.000304841743264548!GO:0008654;phospholipid biosynthetic process;0.000304841743264548!GO:0022415;viral reproductive process;0.000317053779785774!GO:0022403;cell cycle phase;0.000318073885326747!GO:0043038;amino acid activation;0.000319771028551409!GO:0006418;tRNA aminoacylation for protein translation;0.000319771028551409!GO:0043039;tRNA aminoacylation;0.000319771028551409!GO:0019783;small conjugating protein-specific protease activity;0.000323432667267527!GO:0005774;vacuolar membrane;0.000327179426001307!GO:0000122;negative regulation of transcription from RNA polymerase II promoter;0.000329209550893522!GO:0015631;tubulin binding;0.000357417654559983!GO:0007050;cell cycle arrest;0.000360169252011487!GO:0016251;general RNA polymerase II transcription factor activity;0.000370500038532967!GO:0005083;small GTPase regulator activity;0.000377678503960952!GO:0051188;cofactor biosynthetic process;0.000388345097637285!GO:0008287;protein serine/threonine phosphatase complex;0.000412158946310487!GO:0006468;protein amino acid phosphorylation;0.000429427554557705!GO:0042101;T cell receptor complex;0.000430339668690768!GO:0030384;phosphoinositide metabolic process;0.000437725752573634!GO:0045935;positive regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process;0.000461036433319158!GO:0046983;protein dimerization activity;0.000473566243132731!GO:0004843;ubiquitin-specific protease activity;0.000476206325973655!GO:0015630;microtubule cytoskeleton;0.000493462867722647!GO:0005885;Arp2/3 protein complex;0.000505808845939589!GO:0043492;ATPase activity, coupled to movement of substances;0.000509244691395167!GO:0003690;double-stranded DNA binding;0.000509244691395167!GO:0006310;DNA recombination;0.000509857237011278!GO:0046822;regulation of nucleocytoplasmic transport;0.000534671114234249!GO:0042626;ATPase activity, coupled to transmembrane movement of substances;0.000564735145206748!GO:0006607;NLS-bearing substrate import into nucleus;0.000564968058359873!GO:0006261;DNA-dependent DNA replication;0.000567836695378567!GO:0006612;protein targeting to membrane;0.000607968788461585!GO:0031252;leading edge;0.000615433713876156!GO:0005765;lysosomal membrane;0.000645140814294032!GO:0015077;monovalent inorganic cation transmembrane transporter activity;0.000654369040933171!GO:0016820;hydrolase activity, acting on acid anhydrides, catalyzing transmembrane movement of substances;0.000746484591761282!GO:0006611;protein export from nucleus;0.000776768727490687!GO:0005798;Golgi-associated vesicle;0.000786137694150512!GO:0051223;regulation of protein transport;0.000792986985761411!GO:0001819;positive regulation of cytokine production;0.000807854971499613!GO:0006099;tricarboxylic acid cycle;0.000813240200165557!GO:0046356;acetyl-CoA catabolic process;0.000813240200165557!GO:0031902;late endosome membrane;0.000826061678989482!GO:0045941;positive regulation of transcription;0.000866891080086677!GO:0048471;perinuclear region of cytoplasm;0.000866891080086677!GO:0033178;proton-transporting two-sector ATPase complex, catalytic domain;0.000890690227140903!GO:0016311;dephosphorylation;0.00103196947220839!GO:0044437;vacuolar part;0.00105584906832303!GO:0051090;regulation of transcription factor activity;0.0010932532048079!GO:0051251;positive regulation of lymphocyte activation;0.0011059850243333!GO:0005637;nuclear inner membrane;0.00115217757173707!GO:0051336;regulation of hydrolase activity;0.00117447249856162!GO:0009055;electron carrier activity;0.00125769618002389!GO:0006650;glycerophospholipid metabolic process;0.00128030201034054!GO:0004221;ubiquitin thiolesterase activity;0.00130120154564758!GO:0009108;coenzyme biosynthetic process;0.00131514096323456!GO:0045893;positive regulation of transcription, DNA-dependent;0.00132664526324151!GO:0006891;intra-Golgi vesicle-mediated transport;0.00133917847364519!GO:0006950;response to stress;0.00138769851718446!GO:0051338;regulation of transferase activity;0.00140036557659792!GO:0032940;secretion by cell;0.00144972395528663!GO:0005741;mitochondrial outer membrane;0.00147880302116379!GO:0006084;acetyl-CoA metabolic process;0.00149398205254813!GO:0002474;antigen processing and presentation of peptide antigen via MHC class I;0.00153118199555484!GO:0030658;transport vesicle membrane;0.00162434229488097!GO:0042802;identical protein binding;0.00165826987910963!GO:0007034;vacuolar transport;0.00173780478607175!GO:0045261;proton-transporting ATP synthase complex, catalytic core F(1);0.00176380206725029!GO:0003725;double-stranded RNA binding;0.00193651382863164!GO:0006752;group transfer coenzyme metabolic process;0.00204842185485776!GO:0043549;regulation of kinase activity;0.00208645449879546!GO:0043021;ribonucleoprotein binding;0.00210650491069618!GO:0051329;interphase of mitotic cell cycle;0.0021145231271165!GO:0019867;outer membrane;0.00215821865835856!GO:0009893;positive regulation of metabolic process;0.00219894141245932!GO:0046966;thyroid hormone receptor binding;0.0021992915399868!GO:0005096;GTPase activator activity;0.00229546170857177!GO:0033673;negative regulation of kinase activity;0.00235565945790944!GO:0006469;negative regulation of protein kinase activity;0.00235565945790944!GO:0031968;organelle outer membrane;0.00242697768541516!GO:0051789;response to protein stimulus;0.00243283747472129!GO:0006986;response to unfolded protein;0.00243283747472129!GO:0051252;regulation of RNA metabolic process;0.00244073817736367!GO:0046489;phosphoinositide biosynthetic process;0.00248350707180494!GO:0005048;signal sequence binding;0.00256328361724341!GO:0030097;hemopoiesis;0.00265563219328652!GO:0000087;M phase of mitotic cell cycle;0.0027197331872105!GO:0051325;interphase;0.00276437541870675!GO:0006414;translational elongation;0.00294988518410882!GO:0006919;caspase activation;0.00297932187990495!GO:0043488;regulation of mRNA stability;0.00316431223950234!GO:0043487;regulation of RNA stability;0.00316431223950234!GO:0051348;negative regulation of transferase activity;0.00321769125639196!GO:0031625;ubiquitin protein ligase binding;0.00321885191180931!GO:0031982;vesicle;0.00322726897703537!GO:0008139;nuclear localization sequence binding;0.00350526119326577!GO:0019843;rRNA binding;0.0035599201431112!GO:0008017;microtubule binding;0.0035599201431112!GO:0030660;Golgi-associated vesicle membrane;0.0035599201431112!GO:0007067;mitosis;0.00356772721451636!GO:0005753;mitochondrial proton-transporting ATP synthase complex;0.00362602752656036!GO:0016585;chromatin remodeling complex;0.0038303542970534!GO:0045859;regulation of protein kinase activity;0.00385649495604096!GO:0006338;chromatin remodeling;0.0038574485590415!GO:0006405;RNA export from nucleus;0.00398626024893968!GO:0016584;nucleosome positioning;0.00402459656326659!GO:0005852;eukaryotic translation initiation factor 3 complex;0.00412732635716784!GO:0016791;phosphoric monoester hydrolase activity;0.004167384903044!GO:0001775;cell activation;0.00418980524227237!GO:0045045;secretory pathway;0.00428660671623342!GO:0031072;heat shock protein binding;0.00429720984654205!GO:0051301;cell division;0.00430359020982347!GO:0008022;protein C-terminus binding;0.00446491852848474!GO:0043280;positive regulation of caspase activity;0.00449237781656549!GO:0017091;AU-rich element binding;0.00449237781656549!GO:0050779;RNA destabilization;0.00449237781656549!GO:0000289;poly(A) tail shortening;0.00449237781656549!GO:0043281;regulation of caspase activity;0.00461431050457731!GO:0009109;coenzyme catabolic process;0.00471875003779542!GO:0003746;translation elongation factor activity;0.00475629646671858!GO:0004722;protein serine/threonine phosphatase activity;0.00493803822045254!GO:0000184;mRNA catabolic process, nonsense-mediated decay;0.00513230414970787!GO:0018193;peptidyl-amino acid modification;0.00514223744732191!GO:0016679;oxidoreductase activity, acting on diphenols and related substances as donors;0.00527782917205639!GO:0016681;oxidoreductase activity, acting on diphenols and related substances as donors, cytochrome as acceptor;0.00527782917205639!GO:0008121;ubiquinol-cytochrome-c reductase activity;0.00527782917205639!GO:0002520;immune system development;0.00534042698535723!GO:0006383;transcription from RNA polymerase III promoter;0.00539842640829138!GO:0016281;eukaryotic translation initiation factor 4F complex;0.00540894245919882!GO:0005057;receptor signaling protein activity;0.00541717552967874!GO:0005669;transcription factor TFIID complex;0.0054545660246854!GO:0030518;steroid hormone receptor signaling pathway;0.00567165255621256!GO:0019904;protein domain specific binding;0.00591093197205738!GO:0004428;inositol or phosphatidylinositol kinase activity;0.00592660733486919!GO:0046474;glycerophospholipid biosynthetic process;0.00592836986256735!GO:0005684;U2-dependent spliceosome;0.00596491072257571!GO:0051092;activation of NF-kappaB transcription factor;0.00603909309991908!GO:0051052;regulation of DNA metabolic process;0.00611560014899793!GO:0003682;chromatin binding;0.00611560014899793!GO:0008637;apoptotic mitochondrial changes;0.00628745230413944!GO:0030258;lipid modification;0.00628745230413944!GO:0004715;non-membrane spanning protein tyrosine kinase activity;0.00632632360637981!GO:0033157;regulation of intracellular protein transport;0.00632632360637981!GO:0042306;regulation of protein import into nucleus;0.00632632360637981!GO:0006367;transcription initiation from RNA polymerase II promoter;0.00636078227016254!GO:0019901;protein kinase binding;0.0065012260781824!GO:0002757;immune response-activating signal transduction;0.00652542836775123!GO:0006470;protein amino acid dephosphorylation;0.00674549653828272!GO:0003899;DNA-directed RNA polymerase activity;0.00678662206396979!GO:0045603;positive regulation of endothelial cell differentiation;0.00693613637967266!GO:0051098;regulation of binding;0.00700783554158795!GO:0004672;protein kinase activity;0.00717315292861234!GO:0016605;PML body;0.00730215407800748!GO:0051187;cofactor catabolic process;0.00733538113525472!GO:0043087;regulation of GTPase activity;0.00766875602226955!GO:0042287;MHC protein binding;0.007671337456098!GO:0003702;RNA polymerase II transcription factor activity;0.00789059355425762!GO:0002429;immune response-activating cell surface receptor signaling pathway;0.00794895534145133!GO:0048500;signal recognition particle;0.00816202706458074!GO:0004721;phosphoprotein phosphatase activity;0.00823194527028468!GO:0016790;thiolester hydrolase activity;0.00839245444272742!GO:0030118;clathrin coat;0.00871783294303087!GO:0055086;nucleobase, nucleoside and nucleotide metabolic process;0.00884132646849067!GO:0006984;ER-nuclear signaling pathway;0.00888719497855617!GO:0031410;cytoplasmic vesicle;0.00899576707030694!GO:0048487;beta-tubulin binding;0.0089967899302313!GO:0030521;androgen receptor signaling pathway;0.00911239422896266!GO:0004437;inositol or phosphatidylinositol phosphatase activity;0.00928885928251116!GO:0030127;COPII vesicle coat;0.00958096507908174!GO:0012507;ER to Golgi transport vesicle membrane;0.00958096507908174!GO:0000118;histone deacetylase complex;0.00963099064085106!GO:0007041;lysosomal transport;0.00987087132817114!GO:0003684;damaged DNA binding;0.00998138246295822!GO:0046467;membrane lipid biosynthetic process;0.0099879883663282!GO:0051059;NF-kappaB binding;0.0100500324883463!GO:0000786;nucleosome;0.0100853058963153!GO:0031901;early endosome membrane;0.0102983207242352!GO:0000059;protein import into nucleus, docking;0.0103176490495412!GO:0006818;hydrogen transport;0.0103176490495412!GO:0003678;DNA helicase activity;0.010390492174537!GO:0000082;G1/S transition of mitotic cell cycle;0.0106396707787264!GO:0030217;T cell differentiation;0.0110998569229227!GO:0015992;proton transport;0.0117067933634888!GO:0019210;kinase inhibitor activity;0.0117459339696302!GO:0016788;hydrolase activity, acting on ester bonds;0.0118144001578735!GO:0019058;viral infectious cycle;0.0118399626353763!GO:0003711;transcription elongation regulator activity;0.0120658064875869!GO:0051235;maintenance of localization;0.012082743787268!GO:0031325;positive regulation of cellular metabolic process;0.0121716997279525!GO:0000209;protein polyubiquitination;0.0123748944094292!GO:0006302;double-strand break repair;0.0123819052317281!GO:0031988;membrane-bound vesicle;0.012391773435106!GO:0043433;negative regulation of transcription factor activity;0.012391773435106!GO:0033116;ER-Golgi intermediate compartment membrane;0.012391773435106!GO:0030867;rough endoplasmic reticulum membrane;0.0124527483193133!GO:0006376;mRNA splice site selection;0.0124664531420672!GO:0000389;nuclear mRNA 3'-splice site recognition;0.0124664531420672!GO:0032200;telomere organization and biogenesis;0.0128951617792615!GO:0000723;telomere maintenance;0.0128951617792615!GO:0043407;negative regulation of MAP kinase activity;0.012935852942763!GO:0019079;viral genome replication;0.013200461665342!GO:0000079;regulation of cyclin-dependent protein kinase activity;0.013200461665342!GO:0002764;immune response-regulating signal transduction;0.0133470439480046!GO:0004860;protein kinase inhibitor activity;0.0137021429736937!GO:0001817;regulation of cytokine production;0.0137326135052088!GO:0030968;unfolded protein response;0.0141177719577309!GO:0030134;ER to Golgi transport vesicle;0.0145842534302805!GO:0030522;intracellular receptor-mediated signaling pathway;0.0147677193026029!GO:0005657;replication fork;0.0148630315929882!GO:0008624;induction of apoptosis by extracellular signals;0.0148729733687414!GO:0050865;regulation of cell activation;0.0149141242135623!GO:0005521;lamin binding;0.0149571236251511!GO:0031098;stress-activated protein kinase signaling pathway;0.014984582766953!GO:0043621;protein self-association;0.0152324046049245!GO:0004527;exonuclease activity;0.0152661451806967!GO:0042990;regulation of transcription factor import into nucleus;0.0157199145974278!GO:0042991;transcription factor import into nucleus;0.0157199145974278!GO:0051539;4 iron, 4 sulfur cluster binding;0.0157199145974278!GO:0043414;biopolymer methylation;0.0157754911988573!GO:0040029;regulation of gene expression, epigenetic;0.0157959578173152!GO:0006614;SRP-dependent cotranslational protein targeting to membrane;0.0157959578173152!GO:0045047;protein targeting to ER;0.0157959578173152!GO:0045069;regulation of viral genome replication;0.0157997888553389!GO:0002768;immune response-regulating cell surface receptor signaling pathway;0.016485506124339!GO:0008312;7S RNA binding;0.0165356289480358!GO:0044452;nucleolar part;0.0165561580425508!GO:0050871;positive regulation of B cell activation;0.0168540711180276!GO:0030036;actin cytoskeleton organization and biogenesis;0.0171170344938983!GO:0006955;immune response;0.017456358113722!GO:0046854;phosphoinositide phosphorylation;0.0175174330207733!GO:0005819;spindle;0.0175361885567128!GO:0042771;DNA damage response, signal transduction by p53 class mediator resulting in induction of apoptosis;0.017566131953995!GO:0000119;mediator complex;0.0176254609555495!GO:0000279;M phase;0.0177198800314247!GO:0008276;protein methyltransferase activity;0.0178864920587892!GO:0051249;regulation of lymphocyte activation;0.0180445389875863!GO:0032318;regulation of Ras GTPase activity;0.0181320008700034!GO:0005791;rough endoplasmic reticulum;0.0182826895423693!GO:0005762;mitochondrial large ribosomal subunit;0.0183775003320959!GO:0000315;organellar large ribosomal subunit;0.0183775003320959!GO:0000049;tRNA binding;0.0184508269398783!GO:0035026;leading edge cell differentiation;0.0186122953033267!GO:0047485;protein N-terminus binding;0.0191847996251617!GO:0005838;proteasome regulatory particle (sensu Eukaryota);0.0192289656802796!GO:0008601;protein phosphatase type 2A regulator activity;0.0196103566017446!GO:0015923;mannosidase activity;0.0202417026907281!GO:0045058;T cell selection;0.0202507345975089!GO:0022411;cellular component disassembly;0.0207162683140359!GO:0000781;chromosome, telomeric region;0.0212438987809575!GO:0048534;hemopoietic or lymphoid organ development;0.0212467464339178!GO:0050811;GABA receptor binding;0.0213116455526523!GO:0050870;positive regulation of T cell activation;0.0213144994636255!GO:0043022;ribosome binding;0.0215838170333058!GO:0000060;protein import into nucleus, translocation;0.0216339808699982!GO:0030330;DNA damage response, signal transduction by p53 class mediator;0.0223061044923225!GO:0043681;protein import into mitochondrion;0.0224837463494778!GO:0006661;phosphatidylinositol biosynthetic process;0.0225588461426686!GO:0032386;regulation of intracellular transport;0.0227787342286989!GO:0008629;induction of apoptosis by intracellular signals;0.0231650896284975!GO:0046578;regulation of Ras protein signal transduction;0.0233079870116322!GO:0006643;membrane lipid metabolic process;0.0233357578112504!GO:0033549;MAP kinase phosphatase activity;0.023577777614715!GO:0017017;MAP kinase tyrosine/serine/threonine phosphatase activity;0.023577777614715!GO:0045746;negative regulation of Notch signaling pathway;0.023577777614715!GO:0005786;signal recognition particle, endoplasmic reticulum targeting;0.0242260525144508!GO:0001726;ruffle;0.0243022365779782!GO:0030099;myeloid cell differentiation;0.0243022365779782!GO:0006672;ceramide metabolic process;0.0247728469437291!GO:0016023;cytoplasmic membrane-bound vesicle;0.0248627746302202!GO:0019900;kinase binding;0.0248723118312797!GO:0046426;negative regulation of JAK-STAT cascade;0.0248723118312797!GO:0032508;DNA duplex unwinding;0.0249606190410827!GO:0032392;DNA geometric change;0.0249606190410827!GO:0002521;leukocyte differentiation;0.0250498693357232!GO:0003755;peptidyl-prolyl cis-trans isomerase activity;0.0250919571694086!GO:0000188;inactivation of MAPK activity;0.0253004646598044!GO:0005665;DNA-directed RNA polymerase II, core complex;0.0253004646598044!GO:0045263;proton-transporting ATP synthase complex, coupling factor F(o);0.0259163641716078!GO:0033177;proton-transporting two-sector ATPase complex, proton-transporting domain;0.0259163641716078!GO:0051091;positive regulation of transcription factor activity;0.0260294966441972!GO:0046834;lipid phosphorylation;0.0263197733563264!GO:0005869;dynactin complex;0.0263197733563264!GO:0045185;maintenance of protein localization;0.0265001714593081!GO:0004402;histone acetyltransferase activity;0.026852995453782!GO:0004468;lysine N-acetyltransferase activity;0.026852995453782!GO:0007006;mitochondrial membrane organization and biogenesis;0.027167091343702!GO:0002440;production of molecular mediator of immune response;0.0272056410447326!GO:0006595;polyamine metabolic process;0.0276213307819064!GO:0016044;membrane organization and biogenesis;0.027863602820727!GO:0006289;nucleotide-excision repair;0.0279239245433426!GO:0008168;methyltransferase activity;0.0286038681436234!GO:0046979;TAP2 binding;0.0286038681436234!GO:0046977;TAP binding;0.0286038681436234!GO:0046978;TAP1 binding;0.0286038681436234!GO:0016279;protein-lysine N-methyltransferase activity;0.0286220801449347!GO:0018024;histone-lysine N-methyltransferase activity;0.0286220801449347!GO:0016278;lysine N-methyltransferase activity;0.0286220801449347!GO:0000287;magnesium ion binding;0.0286947181705333!GO:0046519;sphingoid metabolic process;0.0289576350416859!GO:0007004;telomere maintenance via telomerase;0.0290003291213906!GO:0007254;JNK cascade;0.0293214656497579!GO:0031461;cullin-RING ubiquitin ligase complex;0.0293710753517826!GO:0045637;regulation of myeloid cell differentiation;0.02937384214985!GO:0016741;transferase activity, transferring one-carbon groups;0.0296230643108128!GO:0030880;RNA polymerase complex;0.030291184175833!GO:0005099;Ras GTPase activator activity;0.0313158377691968!GO:0006914;autophagy;0.0313158377691968!GO:0004518;nuclease activity;0.0315001962411423!GO:0003950;NAD+ ADP-ribosyltransferase activity;0.0316630280277376!GO:0030145;manganese ion binding;0.0318807787493742!GO:0032259;methylation;0.0319443881106953!GO:0016569;covalent chromatin modification;0.0323084973707767!GO:0030374;ligand-dependent nuclear receptor transcription coactivator activity;0.0324727146532992!GO:0006354;RNA elongation;0.0324727146532992!GO:0007259;JAK-STAT cascade;0.0324727146532992!GO:0016859;cis-trans isomerase activity;0.0325256232125625!GO:0016566;specific transcriptional repressor activity;0.0330877254279188!GO:0050851;antigen receptor-mediated signaling pathway;0.0343480499958757!GO:0000303;response to superoxide;0.0344127367260638!GO:0032507;maintenance of cellular protein localization;0.0347622586718727!GO:0000159;protein phosphatase type 2A complex;0.0349010679065065!GO:0006626;protein targeting to mitochondrion;0.0352663611279226!GO:0030137;COPI-coated vesicle;0.0354660606184085!GO:0016570;histone modification;0.0356029144687351!GO:0002763;positive regulation of myeloid leukocyte differentiation;0.0358087259729675!GO:0006368;RNA elongation from RNA polymerase II promoter;0.0360215974802359!GO:0050863;regulation of T cell activation;0.036098759166685!GO:0030674;protein binding, bridging;0.0362919026892397!GO:0001667;ameboidal cell migration;0.0367782991221075!GO:0032027;myosin light chain binding;0.0367782991221075!GO:0051056;regulation of small GTPase mediated signal transduction;0.037067546977595!GO:0030218;erythrocyte differentiation;0.0375591751038763!GO:0050852;T cell receptor signaling pathway;0.0375591751038763!GO:0045736;negative regulation of cyclin-dependent protein kinase activity;0.0376456976140916!GO:0043161;proteasomal ubiquitin-dependent protein catabolic process;0.0381221204873766!GO:0007030;Golgi organization and biogenesis;0.0384452925498768!GO:0022890;inorganic cation transmembrane transporter activity;0.0386251797223593!GO:0030433;ER-associated protein catabolic process;0.0386251797223593!GO:0006515;misfolded or incompletely synthesized protein catabolic process;0.0386251797223593!GO:0033239;negative regulation of amine metabolic process;0.0391833319620335!GO:0045763;negative regulation of amino acid metabolic process;0.0391833319620335!GO:0001933;negative regulation of protein amino acid phosphorylation;0.0391833319620335!GO:0042532;negative regulation of tyrosine phosphorylation of STAT protein;0.0397306897560913!GO:0042518;negative regulation of tyrosine phosphorylation of Stat3 protein;0.0397306897560913!GO:0050732;negative regulation of peptidyl-tyrosine phosphorylation;0.0397306897560913!GO:0048002;antigen processing and presentation of peptide antigen;0.0398321905695362!GO:0004197;cysteine-type endopeptidase activity;0.0402443493626944!GO:0055029;nuclear DNA-directed RNA polymerase complex;0.0412614819190608!GO:0000428;DNA-directed RNA polymerase complex;0.0412614819190608!GO:0001836;release of cytochrome c from mitochondria;0.0413930462789693!GO:0030176;integral to endoplasmic reticulum membrane;0.0414603039709149!GO:0000339;RNA cap binding;0.0416348011275079!GO:0045926;negative regulation of growth;0.0416626657950803!GO:0019220;regulation of phosphate metabolic process;0.0417792625323236!GO:0051174;regulation of phosphorus metabolic process;0.0417792625323236!GO:0045792;negative regulation of cell size;0.0417960490033363!GO:0030663;COPI coated vesicle membrane;0.0419931389417258!GO:0030126;COPI vesicle coat;0.0419931389417258!GO:0009299;mRNA transcription;0.0420459028087716!GO:0000288;mRNA catabolic process, deadenylation-dependent decay;0.0420896608054192!GO:0009117;nucleotide metabolic process;0.0430959518813536!GO:0030125;clathrin vesicle coat;0.0433976240473826!GO:0030665;clathrin coated vesicle membrane;0.0433976240473826!GO:0006839;mitochondrial transport;0.0443550626485072!GO:0008033;tRNA processing;0.04506933179617!GO:0005788;endoplasmic reticulum lumen;0.0452651878938055!GO:0046982;protein heterodimerization activity;0.0453583713163046!GO:0035035;histone acetyltransferase binding;0.046176468708046!GO:0008536;Ran GTPase binding;0.0466455733479642!GO:0051087;chaperone binding;0.0467059633771125!GO:0019883;antigen processing and presentation of endogenous antigen;0.0474731275463052!GO:0031647;regulation of protein stability;0.0474877452102421!GO:0008097;5S rRNA binding;0.0474877452102421!GO:0042608;T cell receptor binding;0.0482083811837243!GO:0051051;negative regulation of transport;0.0487647104505779!GO:0006926;virus-infected cell apoptosis;0.0493629990209338 | |||
|sample_id=11387 | |||
|sample_note= | |||
|sample_sex=male | |||
|sample_species=Human (Homo sapiens) | |||
|sample_strain= | |||
|sample_tissue=blood | |||
|top_motifs=PAX3,7:3.92480849766;RORA:3.73620423722;CREB1:3.68674465084;ATF4:3.63012502111;ATF5_CREB3:3.44412721674;RFX2..5_RFXANK_RFXAP:3.44029153181;RUNX1..3:3.43134499472;NFKB1_REL_RELA:3.12909292256;FOX{D1,D2}:3.05498544283;BPTF:2.98591698289;PAX2:2.74528227082;FOXO1,3,4:2.74501368098;PITX1..3:2.72120159627;T:2.71767618255;FOXP1:2.58713334956;ELF1,2,4:2.57384628841;ETS1,2:2.52063711526;RFX1:2.44107169574;FOXN1:2.40690427759;DMAP1_NCOR{1,2}_SMARC:2.38468603333;ZBTB16:2.13484100227;FOX{F1,F2,J1}:2.10619523971;SPI1:2.06438895822;JUN:2.0554202911;TOPORS:1.97796580652;NKX2-1,4:1.95532649486;HMX1:1.95189728709;TGIF1:1.89082753814;TBX4,5:1.70250588751;IRF1,2:1.52938073082;ATF2:1.52463012005;SPIB:1.49430755133;HIF1A:1.43663195025;NKX6-1,2:1.40769414308;IKZF2:1.33153359243;ATF6:1.33067541288;TLX2:1.20564941322;ZNF384:1.19336299375;BREu{core}:1.10065316064;FOS_FOS{B,L1}_JUN{B,D}:0.983151606592;FOSL2:0.905133608831;NANOG{mouse}:0.781848940111;EP300:0.767804095243;SREBF1,2:0.736269348331;MAFB:0.729746173847;NFATC1..3:0.682424079553;BACH2:0.679165109207;EGR1..3:0.667408452412;LEF1_TCF7_TCF7L1,2:0.654244549567;HMGA1,2:0.634055894021;NFIL3:0.625452805661;PAX4:0.556246146659;PAX6:0.543744976305;FOXL1:0.535916661894;IRF7:0.530712341122;SOX2:0.48014415846;ELK1,4_GABP{A,B1}:0.478598204674;NFE2:0.472038133611;TFDP1:0.453954143316;HBP1_HMGB_SSRP1_UBTF:0.453666655493;FOX{I1,J2}:0.435228203696;FOXP3:0.432626957951;RREB1:0.359189040709;MYB:0.333809826416;AIRE:0.279035260919;CDX1,2,4:0.261993492421;PPARG:0.26034512684;FOXD3:0.223294580474;SMAD1..7,9:0.213097413236;NFE2L1:0.18946495382;RXRA_VDR{dimer}:0.184735543017;CEBPA,B_DDIT3:0.162450726986;STAT2,4,6:0.120654024656;PDX1:0.0772346801502;NKX3-1:0.0664982221682;GATA6:0.0289088812657;AHR_ARNT_ARNT2:-0.0120545226916;NFY{A,B,C}:-0.0258419509301;NFE2L2:-0.0681142430653;MYFfamily:-0.137199516987;HLF:-0.159529597683;RBPJ:-0.200602240108;GCM1,2:-0.218355503542;POU2F1..3:-0.232171271951;SOX5:-0.24523193276;ZFP161:-0.267535098022;NR5A1,2:-0.278513958142;MTE{core}:-0.285403098934;HOX{A6,A7,B6,B7}:-0.291883676843;FOXQ1:-0.299972236965;CUX2:-0.327915709262;E2F1..5:-0.400414353566;ZEB1:-0.420383909147;PATZ1:-0.439290727055;SRF:-0.441392545521;TFAP4:-0.469489594471;TFAP2B:-0.469937069326;MED-1{core}:-0.493229563993;NRF1:-0.500997638832;DBP:-0.525706976257;PBX1:-0.530572951725;CRX:-0.536391767306;GLI1..3:-0.552040100678;SNAI1..3:-0.57615677679;NFIX:-0.614070308138;TAL1_TCF{3,4,12}:-0.628804859141;SPZ1:-0.629089041132;ALX4:-0.629400099529;EVI1:-0.650517596087;STAT1,3:-0.657599486531;HSF1,2:-0.660563545074;MTF1:-0.673693397071;HES1:-0.718998924499;GATA4:-0.731623819227;TFAP2{A,C}:-0.747445400382;HNF4A_NR2F1,2:-0.75108296308;MYOD1:-0.753025991391;PRRX1,2:-0.754240897065;SP1:-0.755986683022;bHLH_family:-0.759203044154;PAX5:-0.76144782323;SOX{8,9,10}:-0.764981160838;REST:-0.799957375451;NR1H4:-0.807886323915;AR:-0.81262956688;MAZ:-0.839635965756;FOXM1:-0.859759850214;XBP1:-0.863368998753;NHLH1,2:-0.863633170719;HOXA9_MEIS1:-0.86837378506;MZF1:-0.897404438168;NANOG:-0.90484884546;STAT5{A,B}:-0.927294783197;HNF1A:-0.968206371602;LMO2:-0.975936915545;TFCP2:-0.984058285625;MEF2{A,B,C,D}:-0.991978473541;OCT4_SOX2{dimer}:-1.07058860464;ZBTB6:-1.07110933561;FOXA2:-1.12264287471;RXR{A,B,G}:-1.13351958682;HIC1:-1.1689183495;ZNF148:-1.17656983839;ARNT_ARNT2_BHLHB2_MAX_MYC_USF1:-1.21194681187;ZNF423:-1.22844595361;YY1:-1.24261706425;NKX2-2,8:-1.24517739811;RXR{A,B,G}_{NR1H2,PPAR}dimers:-1.27592821182;GFI1:-1.27726376992;ESRRA:-1.30511482754;TBP:-1.3226187504;XCPE1{core}:-1.32822936312;PAX8:-1.36683687291;TEF:-1.3814368194;ZNF143:-1.39027863908;LHX3,4:-1.39068265841;ZIC1..3:-1.39409330054;HOX{A5,B5}:-1.47777336293;MYBL2:-1.50513773126;POU1F1:-1.5751053838;UFEwm:-1.59439041146;POU5F1:-1.61780822371;TP53:-1.66604228805;SOX17:-1.71782285438;GTF2I:-1.77799094264;GTF2A1,2:-1.80919707849;EN1,2:-1.83127851788;ZNF238:-1.84384728114;POU6F1:-1.95510460988;TEAD1:-1.9784583252;TLX1..3_NFIC{dimer}:-2.02775002797;ALX1:-2.04307080094;GZF1:-2.04525542833;PRDM1:-2.06644064359;NKX2-3_NKX2-5:-2.07608325412;CDC5L:-2.09379686633;HAND1,2:-2.09986465821;ONECUT1,2:-2.13379626881;NR6A1:-2.16005508702;GFI1B:-2.16131707284;ESR1:-2.16515454006;ARID5B:-2.18761884913;VSX1,2:-2.19238122958;IKZF1:-2.24033576453;EBF1:-2.31124151104;POU3F1..4:-2.3121966674;HOX{A4,D4}:-2.32105220445;KLF4:-2.50480617668;NKX3-2:-2.89118297256;ADNP_IRX_SIX_ZHX:-2.94545569043;PAX1,9:-2.97362319685;NR3C1:-3.6136818736 | |||
|xref= | |||
|zenbu_report=https://fantom.gsc.riken.jp/zenbu/reports/#miRNA_expression_atlas_human;search_select_hide=table111:FF:11387-118C1;search_select_hide=table117:FF:11387-118C1 | |||
}} | }} |
Latest revision as of 17:56, 4 June 2020
Name: | Natural Killer Cells, donor3 |
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Species: | Human (Homo sapiens) |
Library ID: | CNhs12001 |
Sample type: | primary cells |
Genomic View: | UCSC |
RefEX: | Specific genes |
FANTOM CAT: | 1, 2, 3, 4 |
CAGEd-oPOSSUM: | link |
ZENBU report : | link |
Additional information | ||||||||||||||||||||||||||||
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Sample information
RNA information
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CAGE Accession numbers | ||||||||||||||||||||||||||||||||||||||||||||||
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Download raw sequence, BAM & CTSS | ||||||||||||||
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RNA-Seq Accession numbers | ||||||||||||||||||||||||||||||||
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Relative expression to median (log10)
Transcription factors with enriched expression in this sampleRanked list of transcription factor promoter expression in this sample relative to the median expression in the FANTOM5 collection is shown. Value is log10 transformed.
Co-expression clusters with enriched expression in this sampleRanked list of co-expression cluster expression in this sample relative to the median expression in the FANTOM5 collection is shown. Value is log10 transformed. <br>Analyst:NA <br><br>link to dataset.<br>data
Repeat families with enriched expression in this sample<b>Summary:</b>Ranked list of repeat family expression in this sample relative tothe median expression in the FANTOM5 collection is shown. Value is log10transformed.<br><b>Analyst:</b>NA<br><br>link to dataset.<br>data
TFBS(DNA)motifs over-represented in proximal region of promoters active in this sample
JASPAR motifs<b>Summary:</b>Association of JASPAR motif to the promoter expression in thissample. Pearson's correlation between the number of TFBSs estimated byusing the position-weight matrix for each promoter and its expression isexpressed as Z-score by taking the ones based on random position-weightmatrix, and the tail probability of the normal distribution correspondingto the Z-score is taken as the resulting P-value. Lower P-value indicatesmore (non-random) association of the motif to promoter expression<br><b>Analyst:</b> Michiel de Hoon <br><br><br>link to dataset.<br>data
library id: CNhs12001
FANTOM5 phase1 novel unique motifs<b>Summary:</b>Association of the 169 novel and unique motifs discovered in FANTOM5 phase1 in this sample. Among the de-novo motifs discovered by DMF, HOMER,ChIPMunk, and ScanAll, only novel motifs are selected after comparison with known motif sets, and their clustering based on MACRO-APE resulted in169 novel and unique motifs. Their association to the promoter expression is evaluated in the same way to the JASPAR motif above<br><b>Analyst:</b> Michiel de Hoon <br><br><br>link to dataset.<br>data
library id: CNhs12001
Novel motif | Logo | P-value |
---|---|---|
1 | 1 | 0.818 |
10 | 10 | 0.0135 |
100 | 100 | 0.722 |
101 | 101 | 0.367 |
102 | 102 | 0.847 |
103 | 103 | 0.419 |
104 | 104 | 0.659 |
105 | 105 | 0.605 |
106 | 106 | 0.214 |
107 | 107 | 0.0441 |
108 | 108 | 0.431 |
109 | 109 | 0.984 |
11 | 11 | 0.945 |
110 | 110 | 0.508 |
111 | 111 | 0.564 |
112 | 112 | 0.848 |
113 | 113 | 0.159 |
114 | 114 | 0.907 |
115 | 115 | 0.268 |
116 | 116 | 0.195 |
117 | 117 | 0.0103 |
118 | 118 | 0.356 |
119 | 119 | 0.458 |
12 | 12 | 0.452 |
120 | 120 | 0.2 |
121 | 121 | 0.331 |
122 | 122 | 0.873 |
123 | 123 | 3.48323e-5 |
124 | 124 | 0.567 |
125 | 125 | 0.86 |
126 | 126 | 0.794 |
127 | 127 | 0.667 |
128 | 128 | 0.895 |
129 | 129 | 0.254 |
13 | 13 | 0.372 |
130 | 130 | 0.207 |
131 | 131 | 0.293 |
132 | 132 | 0.155 |
133 | 133 | 0.569 |
134 | 134 | 0.694 |
135 | 135 | 0.192 |
136 | 136 | 0.698 |
137 | 137 | 0.0302 |
138 | 138 | 0.772 |
139 | 139 | 0.22 |
14 | 14 | 0.447 |
140 | 140 | 0.868 |
141 | 141 | 0.683 |
142 | 142 | 0.526 |
143 | 143 | 0.0325 |
144 | 144 | 0.956 |
145 | 145 | 0.569 |
146 | 146 | 0.405 |
147 | 147 | 0.0253 |
148 | 148 | 0.554 |
149 | 149 | 0.115 |
15 | 15 | 0.445 |
150 | 150 | 0.981 |
151 | 151 | 0.476 |
152 | 152 | 0.983 |
153 | 153 | 0.666 |
154 | 154 | 0.124 |
155 | 155 | 0.139 |
156 | 156 | 0.928 |
157 | 157 | 0.883 |
158 | 158 | 0.0174 |
159 | 159 | 0.632 |
16 | 16 | 0.196 |
160 | 160 | 0.0348 |
161 | 161 | 0.723 |
162 | 162 | 0.0179 |
163 | 163 | 0.897 |
164 | 164 | 0.12 |
165 | 165 | 0.839 |
166 | 166 | 0.385 |
167 | 167 | 0.164 |
168 | 168 | 0.807 |
169 | 169 | 0.24 |
17 | 17 | 0.686 |
18 | 18 | 0.618 |
19 | 19 | 0.0405 |
2 | 2 | 0.0747 |
20 | 20 | 0.0961 |
21 | 21 | 0.818 |
22 | 22 | 0.258 |
23 | 23 | 0.879 |
24 | 24 | 0.589 |
25 | 25 | 0.204 |
26 | 26 | 0.946 |
27 | 27 | 0.316 |
28 | 28 | 0.384 |
29 | 29 | 0.153 |
3 | 3 | 0.768 |
30 | 30 | 0.0582 |
31 | 31 | 0.586 |
32 | 32 | 0.00476 |
33 | 33 | 0.503 |
34 | 34 | 0.449 |
35 | 35 | 0.56 |
36 | 36 | 0.0991 |
37 | 37 | 0.557 |
38 | 38 | 0.69 |
39 | 39 | 0.516 |
4 | 4 | 0.976 |
40 | 40 | 0.751 |
41 | 41 | 0.0788 |
42 | 42 | 0.606 |
43 | 43 | 0.549 |
44 | 44 | 0.449 |
45 | 45 | 0.107 |
46 | 46 | 0.821 |
47 | 47 | 0.989 |
48 | 48 | 0.884 |
49 | 49 | 0.3 |
5 | 5 | 0.611 |
50 | 50 | 0.523 |
51 | 51 | 0.961 |
52 | 52 | 0.909 |
53 | 53 | 0.257 |
54 | 54 | 0.966 |
55 | 55 | 0.358 |
56 | 56 | 0.769 |
57 | 57 | 0.723 |
58 | 58 | 0.233 |
59 | 59 | 0.172 |
6 | 6 | 0.882 |
60 | 60 | 0.56 |
61 | 61 | 0.435 |
62 | 62 | 0.411 |
63 | 63 | 0.676 |
64 | 64 | 0.937 |
65 | 65 | 0.584 |
66 | 66 | 0.285 |
67 | 67 | 0.528 |
68 | 68 | 0.878 |
69 | 69 | 0.681 |
7 | 7 | 0.688 |
70 | 70 | 0.276 |
71 | 71 | 0.31 |
72 | 72 | 0.445 |
73 | 73 | 0.463 |
74 | 74 | 0.694 |
75 | 75 | 0.0953 |
76 | 76 | 0.0548 |
77 | 77 | 0.00278 |
78 | 78 | 0.948 |
79 | 79 | 0.628 |
8 | 8 | 0.221 |
80 | 80 | 0.0724 |
81 | 81 | 0.885 |
82 | 82 | 0.902 |
83 | 83 | 0.925 |
84 | 84 | 0.0775 |
85 | 85 | 0.642 |
86 | 86 | 0.0667 |
87 | 87 | 0.852 |
88 | 88 | 0.775 |
89 | 89 | 0.0023 |
9 | 9 | 0.774 |
90 | 90 | 0.843 |
91 | 91 | 0.879 |
92 | 92 | 0.599 |
93 | 93 | 0.765 |
94 | 94 | 0.283 |
95 | 95 | 0.172 |
96 | 96 | 0.836 |
97 | 97 | 0.463 |
98 | 98 | 0.578 |
99 | 99 | 3.40255e-6 |
de novo motifs identified by HOMER in promoters active in this sample<b>Summary:</b>The result of HOMER in this sample is shown.<br><b>Analyst:</b>NA <br>
library id: CNhs12001
FANTOM5 (FF) ontology
Direct parent terms
Ancestor terms (non development)<b>Summary:</b>Connected ontology terms with is_a, part_of or located_in relationship <br><b>Analyst:</b> Hideya Kawaji<br><br>link to source data<br>data
CL: Cell type
0000000 (cell), 0000000 (cell)
0000003 (native cell)
0000988 (hematopoietic cell)
0000548 (animal cell)
0002371 (somatic cell)
0000542 (lymphocyte)
0000219 (motile cell)
0000738 (leukocyte)
0002087 (nongranular leukocyte)
0002242 (nucleate cell)
0000255 (eukaryotic cell)
0000623 (natural killer cell)
FF: FANTOM5
0000102 (sample by type)
0000210 (human sample)
0000002 (in vivo cell sample)
0000101 (sample by species)
0000001 (sample)
0000119 (human natural killer cell sample)
Ancestor terms (development)<b>Summary:</b>Connected ontology terms with develops_from, derives_from or preceded_by relationship <br><b>Analyst:</b> Hideya Kawaji <br><br>link to source data<br>data
CL:0000134 (mesenchymal cell)
CL:0000051 (common lymphoid progenitor)