FF:11892-125E2: Difference between revisions
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{{f5samples | {{f5samples | ||
|ancestors_in_anatomy_facet= | |DRA_sample_Accession=CAGE@SAMD00005885 | ||
|ancestors_in_cell_lineage_facet=CL:0000000,CL:0000003,CL: | |accession_numbers=CAGE;DRX007787;DRR008659;DRZ000084;DRZ001469;DRZ011434;DRZ012819 | ||
|ancestors_in_disease_facet=DOID: | |ancestors_in_anatomy_facet=UBERON:0000468,UBERON:0001737,UBERON:0000064,UBERON:0004119,UBERON:0000062,UBERON:0000061,UBERON:0000465,UBERON:0000063,UBERON:0000477,UBERON:0000467,UBERON:0001062,UBERON:0000480,UBERON:0000072,UBERON:0010317,UBERON:0000065,UBERON:0001004,UBERON:0001557 | ||
|ancestors_in_cell_lineage_facet=CL:0000000,CL:0000003,CL:0000548,CL:0000066,CL:0000255 | |||
|ancestors_in_disease_facet=DOID:4,DOID:162,DOID:14566,DOID:0050687,DOID:305 | |||
|ancestors_in_ff_facet=FF:0000102,FF:0000003,FF:0000210,FF:0000101,FF:0000001,FF:0000625,FF:0000350,FF:0000632,FF:0104978,FF:0000638,FF:0100297,FF:0101120,FF:0011133 | |||
|comment= | |comment= | ||
|created_by= | |created_by= | ||
|creation_date= | |creation_date= | ||
|data_phase=2 | |||
|datafreeze_phase=2 | |||
|def= | |def= | ||
|expression_enrichment_score | |||
|fonse_cell_line=FF:0101120 | |fonse_cell_line=FF:0101120 | ||
|fonse_cell_line_closure=FF:0101120 | |fonse_cell_line_closure=FF:0101120 | ||
| Line 35: | Line 41: | ||
|fonse_treatment_closure=FF:0000625,FF:0000632,FF:0000638,FF:0011133,FF:11892-125E2 | |fonse_treatment_closure=FF:0000625,FF:0000632,FF:0000638,FF:0011133,FF:11892-125E2 | ||
|has_quality= | |has_quality= | ||
|hg19bam=http://fantom.gsc.riken.jp/5/datafiles/latest/basic/human.cell_line.hCAGE/Hep-2%2520cells%2520treated%2520with%2520Streptococci%2520strain%25205448%252c%2520biol_rep3.CNhs13497.11892-125E2.hg19.nobarcode.bam | |||
|hg19ctss=http://fantom.gsc.riken.jp/5/datafiles/latest/basic/human.cell_line.hCAGE/Hep-2%2520cells%2520treated%2520with%2520Streptococci%2520strain%25205448%252c%2520biol_rep3.CNhs13497.11892-125E2.hg19.ctss.bed.gz | |||
|hg19fasta=http://fantom.gsc.riken.jp/5/datafiles/latest/basic/human.cell_line.hCAGE/Hep-2%2520cells%2520treated%2520with%2520Streptococci%2520strain%25205448%252c%2520biol_rep3.CNhs13497.11892-125E2.hg19.nobarcode.rdna.fa.gz | |||
|hg38bam=http://fantom.gsc.riken.jp/5/datafiles/reprocessed/hg38_v2/basic/human.cell_line.hCAGE/Hep-2%2520cells%2520treated%2520with%2520Streptococci%2520strain%25205448%252c%2520biol_rep3.CNhs13497.11892-125E2.hg38.nobarcode.bam | |||
|hg38ctss=http://fantom.gsc.riken.jp/5/datafiles/reprocessed/hg38_v2/basic/human.cell_line.hCAGE/Hep-2%2520cells%2520treated%2520with%2520Streptococci%2520strain%25205448%252c%2520biol_rep3.CNhs13497.11892-125E2.hg38.nobarcode.ctss.bed.gz | |||
|id=FF:11892-125E2 | |id=FF:11892-125E2 | ||
|is_a=EFO:0002091;;FF: | |is_a=EFO:0002091;;FF:0011133 | ||
|is_obsolete= | |||
|library_id=CNhs13497 | |||
|library_id_phase_based=2:CNhs13497 | |||
|microRNAs= | |||
|microRNAs_nn= | |||
|microRNAs_nonnovel_cage=http://fantom.gsc.riken.jp/5/suppl/De_Rie_et_al_2017/vis_viewer/#/human#cage;sample;11892 | |||
|microRNAs_novel_cage=http://fantom.gsc.riken.jp/5/suppl/De_Rie_et_al_2017/vis_viewer_novel/#/human#cage;sample;11892 | |||
|name=Hep-2 cells treated with Streptococci strain 5448, biol_rep3 | |name=Hep-2 cells treated with Streptococci strain 5448, biol_rep3 | ||
|namespace= | |namespace= | ||
| Line 42: | Line 60: | ||
|profile_cagescan=,,, | |profile_cagescan=,,, | ||
|profile_hcage=CNhs13497,LSID1025,release012,COMPLETED | |profile_hcage=CNhs13497,LSID1025,release012,COMPLETED | ||
|profile_rnaseq= | |profile_rnaseq= | ||
|profile_srnaseq=,,, | |profile_srnaseq=,,, | ||
|refex=http://refex.dbcls.jp/genelist.php?lang | |||
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| |||
|rna_box=125 | |rna_box=125 | ||
|rna_catalog_number= | |rna_catalog_number= | ||
| Line 54: | Line 75: | ||
|rna_rin=9.7 | |rna_rin=9.7 | ||
|rna_sample_type=total RNA | |rna_sample_type=total RNA | ||
|rna_tube_id= | |rna_tube_id=1.25E+04 | ||
|rna_weight_ug=10 | |rna_weight_ug=10 | ||
|sample_age=56 | |sample_age=56 | ||
|sample_category=cell lines | |||
|sample_cell_catalog= | |sample_cell_catalog= | ||
|sample_cell_line=Hep-2 | |sample_cell_line=Hep-2 | ||
| Line 69: | Line 91: | ||
|sample_ethnicity= | |sample_ethnicity= | ||
|sample_experimental_condition= | |sample_experimental_condition= | ||
|sample_gostat=GO:0044464;cell part;0!GO:0005622;intracellular;0!GO:0044424;intracellular part;1.16115125487734e-258!GO:0043231;intracellular membrane-bound organelle;4.1114765010597e-213!GO:0043227;membrane-bound organelle;4.1114765010597e-213!GO:0043226;organelle;1.26885347793773e-212!GO:0043229;intracellular organelle;7.34586862426782e-212!GO:0005737;cytoplasm;1.00357993758382e-199!GO:0044422;organelle part;1.14726674341512e-179!GO:0044446;intracellular organelle part;8.77424492282816e-178!GO:0044444;cytoplasmic part;2.47861935365798e-149!GO:0032991;macromolecular complex;3.69782558504912e-123!GO:0030529;ribonucleoprotein complex;1.13526761777028e-102!GO:0005739;mitochondrion;6.97985307381218e-99!GO:0044237;cellular metabolic process;1.13681136805926e-95!GO:0043233;organelle lumen;7.68729105067065e-93!GO:0031974;membrane-enclosed lumen;7.68729105067065e-93!GO:0044238;primary metabolic process;1.23666868906654e-91!GO:0044428;nuclear part;1.81010727342293e-91!GO:0003723;RNA binding;7.69743032434665e-86!GO:0005634;nucleus;2.61996369992041e-83!GO:0043170;macromolecule metabolic process;2.42814403304701e-78!GO:0005515;protein binding;1.29087551795246e-65!GO:0044429;mitochondrial part;1.63753969461572e-64!GO:0006396;RNA processing;1.63753969461572e-64!GO:0043234;protein complex;1.5508775794181e-62!GO:0005840;ribosome;2.45447142537852e-61!GO:0006412;translation;1.05087110189278e-58!GO:0031090;organelle membrane;4.60533305992108e-58!GO:0031967;organelle envelope;2.71960950187501e-56!GO:0031975;envelope;4.35103418014923e-56!GO:0031981;nuclear lumen;2.21430113350499e-54!GO:0003735;structural constituent of ribosome;5.20230996539327e-53!GO:0044249;cellular biosynthetic process;9.48404754842438e-52!GO:0009058;biosynthetic process;1.20558177196481e-51!GO:0016043;cellular component organization and biogenesis;1.45383028343874e-47!GO:0033279;ribosomal subunit;2.29495629708425e-46!GO:0006259;DNA metabolic process;1.65172841947748e-45!GO:0019538;protein metabolic process;4.72591063908173e-44!GO:0043228;non-membrane-bound organelle;7.01421344411096e-44!GO:0043232;intracellular non-membrane-bound organelle;7.01421344411096e-44!GO:0016071;mRNA metabolic process;4.05439167858032e-43!GO:0009059;macromolecule biosynthetic process;8.79634160634835e-43!GO:0015031;protein transport;9.59338672386086e-42!GO:0005829;cytosol;1.03465445814755e-41!GO:0006139;nucleobase, nucleoside, nucleotide and nucleic acid metabolic process;1.12402172380064e-41!GO:0033036;macromolecule localization;2.07405769954086e-41!GO:0005740;mitochondrial envelope;4.60751940786289e-41!GO:0008380;RNA splicing;5.11508497610328e-41!GO:0043283;biopolymer metabolic process;9.91291926399104e-40!GO:0006397;mRNA processing;2.86625507224797e-39!GO:0019866;organelle inner membrane;8.13796512770943e-39!GO:0022613;ribonucleoprotein complex biogenesis and assembly;8.96712449065215e-39!GO:0031966;mitochondrial membrane;1.12873107654707e-38!GO:0044260;cellular macromolecule metabolic process;1.25487806468875e-38!GO:0044267;cellular protein metabolic process;2.38444506693185e-38!GO:0045184;establishment of protein localization;5.46876974922253e-38!GO:0008104;protein localization;2.0428813138425e-37!GO:0006996;organelle organization and biogenesis;7.87548236758563e-37!GO:0005743;mitochondrial inner membrane;1.51659291686698e-36!GO:0065003;macromolecular complex assembly;5.12075500682962e-36!GO:0010467;gene expression;5.37775219980982e-36!GO:0007049;cell cycle;2.12014734842441e-33!GO:0046907;intracellular transport;1.68110918175366e-32!GO:0022607;cellular component assembly;3.32731178906863e-31!GO:0005654;nucleoplasm;4.29686723902807e-31!GO:0005830;cytosolic ribosome (sensu Eukaryota);4.57496624989978e-31!GO:0005681;spliceosome;5.20043193046617e-30!GO:0000166;nucleotide binding;8.9251501431432e-29!GO:0031980;mitochondrial lumen;1.50581256173431e-28!GO:0005759;mitochondrial matrix;1.50581256173431e-28!GO:0006886;intracellular protein transport;1.43928493342813e-27!GO:0005730;nucleolus;3.42959649780475e-27!GO:0016818;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides;3.73959776741915e-27!GO:0016462;pyrophosphatase activity;3.7920783543337e-27!GO:0016817;hydrolase activity, acting on acid anhydrides;5.24707773637857e-27!GO:0006974;response to DNA damage stimulus;2.88519155966779e-26!GO:0017111;nucleoside-triphosphatase activity;3.24080415506635e-26!GO:0044445;cytosolic part;8.6209058181757e-26!GO:0044455;mitochondrial membrane part;8.82855096641218e-26!GO:0006119;oxidative phosphorylation;1.94759382710576e-25!GO:0000278;mitotic cell cycle;3.41286849871193e-25!GO:0015934;large ribosomal subunit;4.5644329477254e-25!GO:0022402;cell cycle process;6.67636584096587e-25!GO:0005694;chromosome;7.52823233217629e-25!GO:0044451;nucleoplasm part;1.20436492421571e-24!GO:0044427;chromosomal part;7.83630455040933e-23!GO:0015935;small ribosomal subunit;1.68729316810199e-22!GO:0006281;DNA repair;2.20425395991568e-22!GO:0003676;nucleic acid binding;4.14394545684299e-22!GO:0051186;cofactor metabolic process;6.16917028844028e-22!GO:0006457;protein folding;1.0697760920126e-21!GO:0012505;endomembrane system;1.55393989989066e-21!GO:0016874;ligase activity;3.97158087470964e-21!GO:0005783;endoplasmic reticulum;1.03504732848188e-20!GO:0006260;DNA replication;1.87417004146392e-20!GO:0051649;establishment of cellular localization;1.87575728977937e-20!GO:0042254;ribosome biogenesis and assembly;2.2842157143224e-20!GO:0051641;cellular localization;2.35775148451557e-20!GO:0022403;cell cycle phase;3.76425453556554e-20!GO:0009719;response to endogenous stimulus;8.47717154134368e-20!GO:0032553;ribonucleotide binding;1.13980674361144e-19!GO:0032555;purine ribonucleotide binding;1.13980674361144e-19!GO:0017076;purine nucleotide binding;1.28124877845336e-19!GO:0005746;mitochondrial respiratory chain;2.5869322402672e-19!GO:0022618;protein-RNA complex assembly;5.42839847951375e-19!GO:0005761;mitochondrial ribosome;5.8057644567063e-19!GO:0000313;organellar ribosome;5.8057644567063e-19!GO:0000087;M phase of mitotic cell cycle;1.80721404393515e-18!GO:0044432;endoplasmic reticulum part;2.35866792225517e-18!GO:0016887;ATPase activity;2.49824079232339e-18!GO:0007067;mitosis;3.80242307373109e-18!GO:0016655;oxidoreductase activity, acting on NADH or NADPH, quinone or similar compound as acceptor;5.9455102929496e-18!GO:0051276;chromosome organization and biogenesis;1.09664356947785e-17!GO:0042623;ATPase activity, coupled;1.3405070850456e-17!GO:0000502;proteasome complex (sensu Eukaryota);1.4221253008569e-17!GO:0005524;ATP binding;1.52399801167735e-17!GO:0006732;coenzyme metabolic process;1.96424596974707e-17!GO:0032559;adenyl ribonucleotide binding;2.16575225074559e-17!GO:0030554;adenyl nucleotide binding;4.09379911650083e-17!GO:0044265;cellular macromolecule catabolic process;4.24652753367451e-17!GO:0050136;NADH dehydrogenase (quinone) activity;4.53849972165132e-17!GO:0003954;NADH dehydrogenase activity;4.53849972165132e-17!GO:0008137;NADH dehydrogenase (ubiquinone) activity;4.53849972165132e-17!GO:0044248;cellular catabolic process;4.58466396582271e-17!GO:0008135;translation factor activity, nucleic acid binding;5.15383800971349e-17!GO:0006399;tRNA metabolic process;5.61562696409534e-17!GO:0005842;cytosolic large ribosomal subunit (sensu Eukaryota);1.63187807603596e-16!GO:0051301;cell division;1.8456278038905e-16!GO:0006512;ubiquitin cycle;2.46716193349627e-16!GO:0044453;nuclear membrane part;3.04960176712963e-16!GO:0000279;M phase;6.48061374104433e-16!GO:0005635;nuclear envelope;1.00896402784758e-15!GO:0000398;nuclear mRNA splicing, via spliceosome;2.08035743655608e-15!GO:0000375;RNA splicing, via transesterification reactions;2.08035743655608e-15!GO:0000377;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile;2.08035743655608e-15!GO:0051603;proteolysis involved in cellular protein catabolic process;2.23329334023237e-15!GO:0006605;protein targeting;2.55836142204468e-15!GO:0042775;organelle ATP synthesis coupled electron transport;3.04210259364635e-15!GO:0042773;ATP synthesis coupled electron transport;3.04210259364635e-15!GO:0031965;nuclear membrane;3.15496897903397e-15!GO:0019941;modification-dependent protein catabolic process;3.96283880417932e-15!GO:0043632;modification-dependent macromolecule catabolic process;3.96283880417932e-15!GO:0005843;cytosolic small ribosomal subunit (sensu Eukaryota);4.37975155225454e-15!GO:0030964;NADH dehydrogenase complex (quinone);5.240536412545e-15!GO:0045271;respiratory chain complex I;5.240536412545e-15!GO:0005747;mitochondrial respiratory chain complex I;5.240536412545e-15!GO:0044257;cellular protein catabolic process;6.14251105828224e-15!GO:0051082;unfolded protein binding;6.35728873411316e-15!GO:0006511;ubiquitin-dependent protein catabolic process;9.46049867083881e-15!GO:0006120;mitochondrial electron transport, NADH to ubiquinone;1.63154909597634e-14!GO:0042175;nuclear envelope-endoplasmic reticulum network;2.09878842367263e-14!GO:0006325;establishment and/or maintenance of chromatin architecture;2.78883299949865e-14!GO:0048770;pigment granule;3.14472564405908e-14!GO:0042470;melanosome;3.14472564405908e-14!GO:0016651;oxidoreductase activity, acting on NADH or NADPH;3.67449528745156e-14!GO:0009057;macromolecule catabolic process;4.09543676735621e-14!GO:0006364;rRNA processing;4.95073069069588e-14!GO:0000785;chromatin;5.52880378098405e-14!GO:0043285;biopolymer catabolic process;5.52880378098405e-14!GO:0005789;endoplasmic reticulum membrane;5.55078115096719e-14!GO:0005643;nuclear pore;6.09153279443607e-14!GO:0009055;electron carrier activity;8.35400676741738e-14!GO:0006323;DNA packaging;9.63566510072502e-14!GO:0016072;rRNA metabolic process;1.49555794214085e-13!GO:0003743;translation initiation factor activity;2.91151792951385e-13!GO:0008134;transcription factor binding;3.51195399950718e-13!GO:0065002;intracellular protein transport across a membrane;3.76010835342754e-13!GO:0009259;ribonucleotide metabolic process;8.23451790298875e-13!GO:0016070;RNA metabolic process;8.23451790298875e-13!GO:0000074;regulation of progression through cell cycle;9.69834474897285e-13!GO:0051726;regulation of cell cycle;1.02329250139589e-12!GO:0051188;cofactor biosynthetic process;1.34209029141656e-12!GO:0048193;Golgi vesicle transport;1.7136541570374e-12!GO:0050657;nucleic acid transport;1.91359573956694e-12!GO:0051236;establishment of RNA localization;1.91359573956694e-12!GO:0050658;RNA transport;1.91359573956694e-12!GO:0006403;RNA localization;2.56852836357885e-12!GO:0006333;chromatin assembly or disassembly;2.88573978663369e-12!GO:0004386;helicase activity;2.88852280829628e-12!GO:0006163;purine nucleotide metabolic process;3.22147860178023e-12!GO:0006413;translational initiation;4.28469893878522e-12!GO:0046930;pore complex;8.27200342363799e-12!GO:0008026;ATP-dependent helicase activity;1.03918150456498e-11!GO:0006913;nucleocytoplasmic transport;1.04331354393137e-11!GO:0055086;nucleobase, nucleoside and nucleotide metabolic process;1.3689079504623e-11!GO:0065004;protein-DNA complex assembly;1.3689079504623e-11!GO:0030163;protein catabolic process;1.43019279798833e-11!GO:0016604;nuclear body;1.43019279798833e-11!GO:0051169;nuclear transport;3.17026268355046e-11!GO:0009150;purine ribonucleotide metabolic process;3.52135009402003e-11!GO:0009260;ribonucleotide biosynthetic process;3.5714328931713e-11!GO:0046961;hydrogen ion transporting ATPase activity, rotational mechanism;5.37468366092193e-11!GO:0006164;purine nucleotide biosynthetic process;5.89303656139353e-11!GO:0015931;nucleobase, nucleoside, nucleotide and nucleic acid transport;6.83457847595029e-11!GO:0016879;ligase activity, forming carbon-nitrogen bonds;1.33882062913809e-10!GO:0051028;mRNA transport;1.67322116726612e-10!GO:0008565;protein transporter activity;1.68716444544786e-10!GO:0005794;Golgi apparatus;1.80527284314011e-10!GO:0016876;ligase activity, forming aminoacyl-tRNA and related compounds;2.04143334817709e-10!GO:0004812;aminoacyl-tRNA ligase activity;2.04143334817709e-10!GO:0016875;ligase activity, forming carbon-oxygen bonds;2.04143334817709e-10!GO:0016491;oxidoreductase activity;2.07592154020734e-10!GO:0009108;coenzyme biosynthetic process;2.30160148611551e-10!GO:0007005;mitochondrion organization and biogenesis;2.34256551570499e-10!GO:0012501;programmed cell death;2.48743957416069e-10!GO:0009117;nucleotide metabolic process;2.90140686313153e-10!GO:0046933;hydrogen ion transporting ATP synthase activity, rotational mechanism;4.17921982267722e-10!GO:0006461;protein complex assembly;4.21396311353111e-10!GO:0006915;apoptosis;4.28345640064424e-10!GO:0009060;aerobic respiration;4.6317316456488e-10!GO:0043038;amino acid activation;4.6317316456488e-10!GO:0006418;tRNA aminoacylation for protein translation;4.6317316456488e-10!GO:0043039;tRNA aminoacylation;4.6317316456488e-10!GO:0006261;DNA-dependent DNA replication;5.52563397211565e-10!GO:0009199;ribonucleoside triphosphate metabolic process;5.63209406186155e-10!GO:0016779;nucleotidyltransferase activity;5.68989958187942e-10!GO:0009152;purine ribonucleotide biosynthetic process;6.28254271382934e-10!GO:0016192;vesicle-mediated transport;6.35488326223443e-10!GO:0009141;nucleoside triphosphate metabolic process;6.63107450360535e-10!GO:0030532;small nuclear ribonucleoprotein complex;8.80999211247266e-10!GO:0006446;regulation of translational initiation;9.77701149531747e-10!GO:0006334;nucleosome assembly;9.89593058539175e-10!GO:0016787;hydrolase activity;1.2393825382804e-09!GO:0009205;purine ribonucleoside triphosphate metabolic process;1.44775627179715e-09!GO:0009144;purine nucleoside triphosphate metabolic process;1.44775627179715e-09!GO:0045333;cellular respiration;1.45543035984556e-09!GO:0015986;ATP synthesis coupled proton transport;1.70624823696829e-09!GO:0015985;energy coupled proton transport, down electrochemical gradient;1.70624823696829e-09!GO:0043412;biopolymer modification;1.71515218730037e-09!GO:0009056;catabolic process;2.28680431579785e-09!GO:0003697;single-stranded DNA binding;2.34651525645563e-09!GO:0008639;small protein conjugating enzyme activity;2.3953425853715e-09!GO:0031497;chromatin assembly;2.81988627758307e-09!GO:0008219;cell death;3.08305751834617e-09!GO:0016265;death;3.08305751834617e-09!GO:0009142;nucleoside triphosphate biosynthetic process;3.55322582316343e-09!GO:0009201;ribonucleoside triphosphate biosynthetic process;3.55322582316343e-09!GO:0006366;transcription from RNA polymerase II promoter;3.80321473868687e-09!GO:0046034;ATP metabolic process;4.17415541475352e-09!GO:0016607;nuclear speck;5.32980425834035e-09!GO:0019787;small conjugating protein ligase activity;7.58167574689385e-09!GO:0004842;ubiquitin-protein ligase activity;7.73289869368746e-09!GO:0009206;purine ribonucleoside triphosphate biosynthetic process;9.57748086262227e-09!GO:0009145;purine nucleoside triphosphate biosynthetic process;9.57748086262227e-09!GO:0017038;protein import;1.1379018424181e-08!GO:0043566;structure-specific DNA binding;1.20735631987256e-08!GO:0019829;cation-transporting ATPase activity;1.44834521129157e-08!GO:0006754;ATP biosynthetic process;2.21339446202071e-08!GO:0006753;nucleoside phosphate metabolic process;2.21339446202071e-08!GO:0051325;interphase;2.2536462221633e-08!GO:0016740;transferase activity;2.2536462221633e-08!GO:0005819;spindle;2.32802801164572e-08!GO:0051329;interphase of mitotic cell cycle;2.39775788031575e-08!GO:0006099;tricarboxylic acid cycle;2.61587390384903e-08!GO:0046356;acetyl-CoA catabolic process;2.61587390384903e-08!GO:0006084;acetyl-CoA metabolic process;2.69087223036981e-08!GO:0006752;group transfer coenzyme metabolic process;3.94041683365583e-08!GO:0008033;tRNA processing;4.13588332477992e-08!GO:0015078;hydrogen ion transmembrane transporter activity;4.44371621486553e-08!GO:0016881;acid-amino acid ligase activity;5.29419525762978e-08!GO:0016469;proton-transporting two-sector ATPase complex;5.55413124504768e-08!GO:0005793;ER-Golgi intermediate compartment;6.52525251179953e-08!GO:0005657;replication fork;8.76114304807472e-08!GO:0000775;chromosome, pericentric region;9.18770873234599e-08!GO:0006091;generation of precursor metabolites and energy;1.13190084442212e-07!GO:0003712;transcription cofactor activity;1.39974816955348e-07!GO:0016568;chromatin modification;1.74396972921301e-07!GO:0003899;DNA-directed RNA polymerase activity;2.00799588373773e-07!GO:0016591;DNA-directed RNA polymerase II, holoenzyme;2.01557041635367e-07!GO:0006464;protein modification process;2.36248631532109e-07!GO:0045259;proton-transporting ATP synthase complex;2.6805291280015e-07!GO:0008094;DNA-dependent ATPase activity;2.6805291280015e-07!GO:0051187;cofactor catabolic process;3.10018187432857e-07!GO:0005762;mitochondrial large ribosomal subunit;3.20520316762851e-07!GO:0000315;organellar large ribosomal subunit;3.20520316762851e-07!GO:0005667;transcription factor complex;3.43554891556548e-07!GO:0043623;cellular protein complex assembly;3.80768241257918e-07!GO:0006888;ER to Golgi vesicle-mediated transport;4.07248884955577e-07!GO:0015630;microtubule cytoskeleton;4.23971404297658e-07!GO:0009109;coenzyme catabolic process;5.09956749563858e-07!GO:0005839;proteasome core complex (sensu Eukaryota);5.36402851631353e-07!GO:0008654;phospholipid biosynthetic process;5.77197188742497e-07!GO:0042981;regulation of apoptosis;6.39632787259431e-07!GO:0000075;cell cycle checkpoint;7.23995782802562e-07!GO:0000245;spliceosome assembly;7.64253323553823e-07!GO:0043067;regulation of programmed cell death;7.69200970085308e-07!GO:0030120;vesicle coat;7.72779444344698e-07!GO:0030662;coated vesicle membrane;7.72779444344698e-07!GO:0007051;spindle organization and biogenesis;9.29721736017934e-07!GO:0032446;protein modification by small protein conjugation;9.83273602304948e-07!GO:0031202;RNA splicing factor activity, transesterification mechanism;1.14019680743092e-06!GO:0000079;regulation of cyclin-dependent protein kinase activity;1.21194375043232e-06!GO:0048475;coated membrane;1.21194375043232e-06!GO:0030117;membrane coat;1.21194375043232e-06!GO:0051427;hormone receptor binding;1.32362678947457e-06!GO:0016567;protein ubiquitination;1.49292714247532e-06!GO:0016853;isomerase activity;1.58345274464719e-06!GO:0005768;endosome;1.58345274464719e-06!GO:0044452;nucleolar part;1.87590223587848e-06!GO:0003724;RNA helicase activity;1.88685313356512e-06!GO:0004298;threonine endopeptidase activity;2.48644172654503e-06!GO:0000786;nucleosome;2.54223821208082e-06!GO:0043687;post-translational protein modification;2.69465283382625e-06!GO:0009165;nucleotide biosynthetic process;2.89152785008898e-06!GO:0035257;nuclear hormone receptor binding;3.31863698402321e-06!GO:0000314;organellar small ribosomal subunit;4.26340636280177e-06!GO:0005763;mitochondrial small ribosomal subunit;4.26340636280177e-06!GO:0051168;nuclear export;4.97172511878815e-06!GO:0016741;transferase activity, transferring one-carbon groups;5.07134680662871e-06!GO:0008168;methyltransferase activity;5.2100664287208e-06!GO:0005788;endoplasmic reticulum lumen;5.81545596950836e-06!GO:0006613;cotranslational protein targeting to membrane;6.25134764031931e-06!GO:0015405;P-P-bond-hydrolysis-driven transmembrane transporter activity;6.28662767173642e-06!GO:0015399;primary active transmembrane transporter activity;6.28662767173642e-06!GO:0006302;double-strand break repair;6.81083999299331e-06!GO:0019752;carboxylic acid metabolic process;6.95884265442444e-06!GO:0006082;organic acid metabolic process;7.042117533441e-06!GO:0015077;monovalent inorganic cation transmembrane transporter activity;7.43962897899318e-06!GO:0000151;ubiquitin ligase complex;7.5506348886774e-06!GO:0051246;regulation of protein metabolic process;7.84896490273229e-06!GO:0046483;heterocycle metabolic process;8.46648242862252e-06!GO:0006626;protein targeting to mitochondrion;8.96376756743463e-06!GO:0051170;nuclear import;9.52716884943374e-06!GO:0006916;anti-apoptosis;9.65873481951726e-06!GO:0005813;centrosome;9.68060637918194e-06!GO:0006414;translational elongation;1.21950370852976e-05!GO:0043069;negative regulation of programmed cell death;1.38193132534578e-05!GO:0048523;negative regulation of cellular process;1.40195821032267e-05!GO:0003924;GTPase activity;1.52189155306089e-05!GO:0019867;outer membrane;1.8538005661494e-05!GO:0045454;cell redox homeostasis;1.9286516315992e-05!GO:0003682;chromatin binding;2.13782838384603e-05!GO:0005815;microtubule organizing center;2.13980383379212e-05!GO:0043066;negative regulation of apoptosis;2.13980383379212e-05!GO:0046474;glycerophospholipid biosynthetic process;2.44052978435734e-05!GO:0031968;organelle outer membrane;2.69472337904704e-05!GO:0006839;mitochondrial transport;2.78710141649678e-05!GO:0006606;protein import into nucleus;3.4447846036779e-05!GO:0015980;energy derivation by oxidation of organic compounds;3.90239477445965e-05!GO:0043123;positive regulation of I-kappaB kinase/NF-kappaB cascade;3.9761722021494e-05!GO:0031324;negative regulation of cellular metabolic process;4.22599882189838e-05!GO:0030867;rough endoplasmic reticulum membrane;5.04728332551039e-05!GO:0043681;protein import into mitochondrion;5.1189071719503e-05!GO:0006383;transcription from RNA polymerase III promoter;5.16048958298112e-05!GO:0016126;sterol biosynthetic process;5.43220367014631e-05!GO:0043021;ribonucleoprotein binding;5.58148503509071e-05!GO:0007249;I-kappaB kinase/NF-kappaB cascade;5.70913627414419e-05!GO:0003684;damaged DNA binding;6.08021113644798e-05!GO:0043122;regulation of I-kappaB kinase/NF-kappaB cascade;7.2769157807316e-05!GO:0030530;heterogeneous nuclear ribonucleoprotein complex;7.31975652539212e-05!GO:0051052;regulation of DNA metabolic process;7.96827957634154e-05!GO:0005753;mitochondrial proton-transporting ATP synthase complex;8.21710733185067e-05!GO:0008186;RNA-dependent ATPase activity;8.47484356070992e-05!GO:0003713;transcription coactivator activity;8.67589458589954e-05!GO:0003755;peptidyl-prolyl cis-trans isomerase activity;8.92684074901691e-05!GO:0044440;endosomal part;9.4169418381306e-05!GO:0010008;endosome membrane;9.4169418381306e-05!GO:0046489;phosphoinositide biosynthetic process;9.8090811961425e-05!GO:0005770;late endosome;9.8096296259707e-05!GO:0016765;transferase activity, transferring alkyl or aryl (other than methyl) groups;0.000101967603953973!GO:0005741;mitochondrial outer membrane;0.000101967603953973!GO:0016859;cis-trans isomerase activity;0.000102079422982755!GO:0007059;chromosome segregation;0.000104942174243195!GO:0003690;double-stranded DNA binding;0.000109468393104502!GO:0045786;negative regulation of progression through cell cycle;0.000112985991217608!GO:0000776;kinetochore;0.000115862986137961!GO:0016627;oxidoreductase activity, acting on the CH-CH group of donors;0.000120033262103889!GO:0016772;transferase activity, transferring phosphorus-containing groups;0.000120033262103889!GO:0007088;regulation of mitosis;0.000121499329511194!GO:0005852;eukaryotic translation initiation factor 3 complex;0.000126190586267132!GO:0006310;DNA recombination;0.000129406128871327!GO:0050662;coenzyme binding;0.000135109415460829!GO:0005525;GTP binding;0.000141791450027205!GO:0004518;nuclease activity;0.000147156592883473!GO:0030880;RNA polymerase complex;0.000154731356145852!GO:0006612;protein targeting to membrane;0.00015515650886972!GO:0009892;negative regulation of metabolic process;0.000161770639334709!GO:0004527;exonuclease activity;0.000163477383988897!GO:0000059;protein import into nucleus, docking;0.00019272771494464!GO:0042625;ATPase activity, coupled to transmembrane movement of ions;0.000201531038409182!GO:0006695;cholesterol biosynthetic process;0.000229129455626567!GO:0004004;ATP-dependent RNA helicase activity;0.000230250251682975!GO:0008610;lipid biosynthetic process;0.000239413267161275!GO:0005773;vacuole;0.000243097112933446!GO:0045934;negative regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process;0.000243505081433275!GO:0003678;DNA helicase activity;0.000246129517984376!GO:0043284;biopolymer biosynthetic process;0.000264873784384289!GO:0051789;response to protein stimulus;0.000266661575797595!GO:0006986;response to unfolded protein;0.000266661575797595!GO:0019843;rRNA binding;0.000273265568498826!GO:0044431;Golgi apparatus part;0.000288734236942626!GO:0006793;phosphorus metabolic process;0.000311633653360938!GO:0006796;phosphate metabolic process;0.000311633653360938!GO:0033178;proton-transporting two-sector ATPase complex, catalytic domain;0.000317384420327497!GO:0048519;negative regulation of biological process;0.000318808199784828!GO:0043596;nuclear replication fork;0.000320760047858114!GO:0043492;ATPase activity, coupled to movement of substances;0.00033719805940124!GO:0005791;rough endoplasmic reticulum;0.000350560726096617!GO:0009112;nucleobase metabolic process;0.000362766415497079!GO:0006520;amino acid metabolic process;0.000363161476620152!GO:0031072;heat shock protein binding;0.000372315268384277!GO:0006650;glycerophospholipid metabolic process;0.000372315268384277!GO:0055029;nuclear DNA-directed RNA polymerase complex;0.000392380391629643!GO:0000428;DNA-directed RNA polymerase complex;0.000392380391629643!GO:0006357;regulation of transcription from RNA polymerase II promoter;0.000394229049558467!GO:0048037;cofactor binding;0.000418423065919399!GO:0042626;ATPase activity, coupled to transmembrane movement of substances;0.000424329571345009!GO:0003729;mRNA binding;0.000426205240376606!GO:0051920;peroxiredoxin activity;0.000492216867747874!GO:0005684;U2-dependent spliceosome;0.000492216867747874!GO:0016891;endoribonuclease activity, producing 5'-phosphomonoesters;0.000504456927268513!GO:0005798;Golgi-associated vesicle;0.000522794331224424!GO:0033116;ER-Golgi intermediate compartment membrane;0.000529174197880153!GO:0032508;DNA duplex unwinding;0.000536884077340913!GO:0032392;DNA geometric change;0.000536884077340913!GO:0051540;metal cluster binding;0.00054010674304747!GO:0051536;iron-sulfur cluster binding;0.00054010674304747!GO:0045261;proton-transporting ATP synthase complex, catalytic core F(1);0.00054010674304747!GO:0016820;hydrolase activity, acting on acid anhydrides, catalyzing transmembrane movement of substances;0.00054010674304747!GO:0048471;perinuclear region of cytoplasm;0.000579556606624564!GO:0016363;nuclear matrix;0.000580533182154018!GO:0005048;signal sequence binding;0.000580533182154018!GO:0042802;identical protein binding;0.000586004624283033!GO:0005838;proteasome regulatory particle (sensu Eukaryota);0.000613786924607877!GO:0035258;steroid hormone receptor binding;0.000681219122940446!GO:0007006;mitochondrial membrane organization and biogenesis;0.000682494724157728!GO:0016893;endonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters;0.000695838862010836!GO:0006118;electron transport;0.00069873882413837!GO:0006275;regulation of DNA replication;0.000720624791326536!GO:0000226;microtubule cytoskeleton organization and biogenesis;0.000725258036002055!GO:0008361;regulation of cell size;0.000725258036002055!GO:0045263;proton-transporting ATP synthase complex, coupling factor F(o);0.000727016639126842!GO:0033177;proton-transporting two-sector ATPase complex, proton-transporting domain;0.000727016639126842!GO:0046467;membrane lipid biosynthetic process;0.000728658107761404!GO:0015992;proton transport;0.000737941896286883!GO:0001558;regulation of cell growth;0.000766122769156997!GO:0000323;lytic vacuole;0.000778471568267882!GO:0005764;lysosome;0.000778471568267882!GO:0016564;transcription repressor activity;0.000785777356941731!GO:0031988;membrane-bound vesicle;0.000815697564349406!GO:0016679;oxidoreductase activity, acting on diphenols and related substances as donors;0.000815862166231187!GO:0016681;oxidoreductase activity, acting on diphenols and related substances as donors, cytochrome as acceptor;0.000815862166231187!GO:0008121;ubiquinol-cytochrome-c reductase activity;0.000815862166231187!GO:0016049;cell growth;0.000848326264216242!GO:0006506;GPI anchor biosynthetic process;0.000848326264216242!GO:0006818;hydrogen transport;0.000855495540911244!GO:0005885;Arp2/3 protein complex;0.000855495540911244!GO:0003711;transcription elongation regulator activity;0.000914931175131383!GO:0000049;tRNA binding;0.000922817291490796!GO:0007052;mitotic spindle organization and biogenesis;0.000971408920484113!GO:0006405;RNA export from nucleus;0.000971464076795148!GO:0016563;transcription activator activity;0.000976816855193197!GO:0009451;RNA modification;0.000991128360430509!GO:0009116;nucleoside metabolic process;0.00103595889642569!GO:0000082;G1/S transition of mitotic cell cycle;0.00106027228100248!GO:0051087;chaperone binding;0.00107038023386002!GO:0006270;DNA replication initiation;0.00108181896904273!GO:0016796;exonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters;0.00109782937395255!GO:0016023;cytoplasmic membrane-bound vesicle;0.00111916426553095!GO:0006284;base-excision repair;0.00112053186158158!GO:0032561;guanyl ribonucleotide binding;0.00112843784665968!GO:0019001;guanyl nucleotide binding;0.00112843784665968!GO:0044262;cellular carbohydrate metabolic process;0.00113129311908887!GO:0016310;phosphorylation;0.00115009396890883!GO:0006268;DNA unwinding during replication;0.00117396290645559!GO:0006950;response to stress;0.00121295950834898!GO:0051287;NAD binding;0.00129031142199379!GO:0048500;signal recognition particle;0.00129509407238285!GO:0030132;clathrin coat of coated pit;0.00132800972089225!GO:0006611;protein export from nucleus;0.00138322176035138!GO:0008312;7S RNA binding;0.00139435309880269!GO:0006767;water-soluble vitamin metabolic process;0.00141738801948584!GO:0006505;GPI anchor metabolic process;0.00145258434006502!GO:0005758;mitochondrial intermembrane space;0.00146779795368994!GO:0030384;phosphoinositide metabolic process;0.00147022430532615!GO:0005905;coated pit;0.00148948488264701!GO:0031252;leading edge;0.00157697233560515!GO:0030176;integral to endoplasmic reticulum membrane;0.00158568223532768!GO:0007093;mitotic cell cycle checkpoint;0.00163934588391202!GO:0043601;nuclear replisome;0.00179954620438537!GO:0030894;replisome;0.00179954620438537!GO:0030118;clathrin coat;0.00185214822319158!GO:0008320;protein transmembrane transporter activity;0.00185831007961823!GO:0003746;translation elongation factor activity;0.00193376382993734!GO:0006007;glucose catabolic process;0.00202585237887876!GO:0000139;Golgi membrane;0.00204532035438884!GO:0065009;regulation of a molecular function;0.00205929848017281!GO:0006497;protein amino acid lipidation;0.00209696529461259!GO:0048487;beta-tubulin binding;0.00216164796656136!GO:0008180;signalosome;0.00228170826438348!GO:0051252;regulation of RNA metabolic process;0.00231565887655732!GO:0008757;S-adenosylmethionine-dependent methyltransferase activity;0.00250415992520539!GO:0005876;spindle microtubule;0.00251321002454721!GO:0006352;transcription initiation;0.00251829093049272!GO:0030663;COPI coated vesicle membrane;0.00255285542575874!GO:0030126;COPI vesicle coat;0.00255285542575874!GO:0042770;DNA damage response, signal transduction;0.00261100369425458!GO:0022884;macromolecule transmembrane transporter activity;0.00285614783544062!GO:0015450;P-P-bond-hydrolysis-driven protein transmembrane transporter activity;0.00285614783544062!GO:0000178;exosome (RNase complex);0.00287663744767993!GO:0005637;nuclear inner membrane;0.0029112901411545!GO:0006595;polyamine metabolic process;0.00293130003076948!GO:0000086;G2/M transition of mitotic cell cycle;0.00296156964279729!GO:0006519;amino acid and derivative metabolic process;0.00302714549174581!GO:0005769;early endosome;0.00303625770145004!GO:0016272;prefoldin complex;0.00306930617594096!GO:0008408;3'-5' exonuclease activity;0.00317484949684349!GO:0006733;oxidoreduction coenzyme metabolic process;0.00317484949684349!GO:0006400;tRNA modification;0.00319929510379227!GO:0022890;inorganic cation transmembrane transporter activity;0.00328316424255905!GO:0005786;signal recognition particle, endoplasmic reticulum targeting;0.00334023453675382!GO:0004532;exoribonuclease activity;0.0034003240350957!GO:0016896;exoribonuclease activity, producing 5'-phosphomonoesters;0.0034003240350957!GO:0006614;SRP-dependent cotranslational protein targeting to membrane;0.0034003240350957!GO:0045047;protein targeting to ER;0.0034003240350957!GO:0000096;sulfur amino acid metabolic process;0.00343737148362646!GO:0000287;magnesium ion binding;0.00349231146444539!GO:0006144;purine base metabolic process;0.00349734162575242!GO:0042393;histone binding;0.00353064635377898!GO:0016481;negative regulation of transcription;0.00356156021935092!GO:0006401;RNA catabolic process;0.00364490912643226!GO:0016281;eukaryotic translation initiation factor 4F complex;0.00376135843044848!GO:0000228;nuclear chromosome;0.00448129203800718!GO:0046982;protein heterodimerization activity;0.00450769928617974!GO:0031982;vesicle;0.00450769928617974!GO:0016676;oxidoreductase activity, acting on heme group of donors, oxygen as acceptor;0.00452544694271385!GO:0015002;heme-copper terminal oxidase activity;0.00452544694271385!GO:0016675;oxidoreductase activity, acting on heme group of donors;0.00452544694271385!GO:0004129;cytochrome-c oxidase activity;0.00452544694271385!GO:0003725;double-stranded RNA binding;0.00465003905464356!GO:0030137;COPI-coated vesicle;0.00480686343956665!GO:0016628;oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor;0.00509495552767293!GO:0006778;porphyrin metabolic process;0.00524793331004343!GO:0033013;tetrapyrrole metabolic process;0.00524793331004343!GO:0004549;tRNA-specific ribonuclease activity;0.00525871573890536!GO:0008139;nuclear localization sequence binding;0.00533527244213112!GO:0048522;positive regulation of cellular process;0.00540620158408617!GO:0004526;ribonuclease P activity;0.00566199057021993!GO:0009124;nucleoside monophosphate biosynthetic process;0.00584117351699313!GO:0009123;nucleoside monophosphate metabolic process;0.00584117351699313!GO:0045792;negative regulation of cell size;0.00605699910539465!GO:0031970;organelle envelope lumen;0.00622097844142929!GO:0006890;retrograde vesicle-mediated transport, Golgi to ER;0.0064608347979981!GO:0007007;inner mitochondrial membrane organization and biogenesis;0.00652182876921962!GO:0006807;nitrogen compound metabolic process;0.0066875872626134!GO:0031410;cytoplasmic vesicle;0.00673023684596513!GO:0006402;mRNA catabolic process;0.0067709682817073!GO:0009303;rRNA transcription;0.00682756177024271!GO:0006289;nucleotide-excision repair;0.00689255727964215!GO:0030308;negative regulation of cell growth;0.00690923543426151!GO:0016044;membrane organization and biogenesis;0.00696013411775577!GO:0006891;intra-Golgi vesicle-mediated transport;0.00696411905195874!GO:0031570;DNA integrity checkpoint;0.00700682906760615!GO:0004003;ATP-dependent DNA helicase activity;0.00700710512088855!GO:0008632;apoptotic program;0.00700710512088855!GO:0008629;induction of apoptosis by intracellular signals;0.00714445986974786!GO:0000725;recombinational repair;0.00721658507202445!GO:0000724;double-strand break repair via homologous recombination;0.00721658507202445!GO:0042158;lipoprotein biosynthetic process;0.00760237557253076!GO:0051539;4 iron, 4 sulfur cluster binding;0.00772151869715696!GO:0003714;transcription corepressor activity;0.00809516408832028!GO:0043624;cellular protein complex disassembly;0.00818890361567502!GO:0004540;ribonuclease activity;0.00847247290972483!GO:0030521;androgen receptor signaling pathway;0.00848159213271918!GO:0008652;amino acid biosynthetic process;0.00848283396833577!GO:0016407;acetyltransferase activity;0.00850883784195038!GO:0005832;chaperonin-containing T-complex;0.00873579129521393!GO:0046983;protein dimerization activity;0.00876395993611746!GO:0016408;C-acyltransferase activity;0.00907333834698786!GO:0032259;methylation;0.00941243155128572!GO:0040008;regulation of growth;0.00945222574177158!GO:0000922;spindle pole;0.00948854078990194!GO:0016125;sterol metabolic process;0.00952930336131298!GO:0030658;transport vesicle membrane;0.00967535638539422!GO:0000339;RNA cap binding;0.00974983324845566!GO:0051338;regulation of transferase activity;0.00997021310658824!GO:0006509;membrane protein ectodomain proteolysis;0.0100415186980821!GO:0033619;membrane protein proteolysis;0.0100415186980821!GO:0046966;thyroid hormone receptor binding;0.0102661305859332!GO:0009119;ribonucleoside metabolic process;0.0102844477585252!GO:0031124;mRNA 3'-end processing;0.0106304829795041!GO:0043022;ribosome binding;0.0107836128682493!GO:0050681;androgen receptor binding;0.0108979318949393!GO:0000307;cyclin-dependent protein kinase holoenzyme complex;0.0112547204047711!GO:0005665;DNA-directed RNA polymerase II, core complex;0.0114467912648653!GO:0006779;porphyrin biosynthetic process;0.0115103850182228!GO:0033014;tetrapyrrole biosynthetic process;0.0115103850182228!GO:0008022;protein C-terminus binding;0.01160241853963!GO:0009308;amine metabolic process;0.0116380796894089!GO:0000175;3'-5'-exoribonuclease activity;0.011769018135485!GO:0043154;negative regulation of caspase activity;0.0118443152622646!GO:0005744;mitochondrial inner membrane presequence translocase complex;0.012087411651356!GO:0030119;AP-type membrane coat adaptor complex;0.0122647747535127!GO:0050790;regulation of catalytic activity;0.0122814300697853!GO:0004523;ribonuclease H activity;0.0129059945042173!GO:0016862;intramolecular oxidoreductase activity, interconverting keto- and enol-groups;0.0129467405652551!GO:0043414;biopolymer methylation;0.0130697041036118!GO:0043549;regulation of kinase activity;0.0130707204418397!GO:0009161;ribonucleoside monophosphate metabolic process;0.0130707204418397!GO:0009156;ribonucleoside monophosphate biosynthetic process;0.0130707204418397!GO:0015631;tubulin binding;0.0131882356344192!GO:0019899;enzyme binding;0.0132478941398276!GO:0005874;microtubule;0.0132705823662968!GO:0006100;tricarboxylic acid cycle intermediate metabolic process;0.0132705823662968!GO:0005862;muscle thin filament tropomyosin;0.0132705823662968!GO:0007010;cytoskeleton organization and biogenesis;0.013713748723338!GO:0007021;tubulin folding;0.013713748723338!GO:0008637;apoptotic mitochondrial changes;0.01371820873668!GO:0006338;chromatin remodeling;0.014002943688293!GO:0006740;NADPH regeneration;0.014002943688293!GO:0006098;pentose-phosphate shunt;0.014002943688293!GO:0030125;clathrin vesicle coat;0.0141186722474715!GO:0030665;clathrin coated vesicle membrane;0.0141186722474715!GO:0016616;oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor;0.0141695304618862!GO:0043488;regulation of mRNA stability;0.0147847974771643!GO:0043487;regulation of RNA stability;0.0147847974771643!GO:0006096;glycolysis;0.0152795375892773!GO:0016614;oxidoreductase activity, acting on CH-OH group of donors;0.0152965307639782!GO:0030131;clathrin adaptor complex;0.0153428990238985!GO:0042719;mitochondrial intermembrane space protein transporter complex;0.0153428990238985!GO:0045039;protein import into mitochondrial inner membrane;0.0153428990238985!GO:0016780;phosphotransferase activity, for other substituted phosphate groups;0.0156410534455859!GO:0032984;macromolecular complex disassembly;0.0157058737913623!GO:0008234;cysteine-type peptidase activity;0.0162494134788977!GO:0016251;general RNA polymerase II transcription factor activity;0.0164339846461621!GO:0043433;negative regulation of transcription factor activity;0.0164339846461621!GO:0044255;cellular lipid metabolic process;0.0164339846461621!GO:0044438;microbody part;0.0164339846461621!GO:0044439;peroxisomal part;0.0164339846461621!GO:0006066;alcohol metabolic process;0.0165044218577036!GO:0030660;Golgi-associated vesicle membrane;0.0167657523766378!GO:0005663;DNA replication factor C complex;0.0170083322010028!GO:0048146;positive regulation of fibroblast proliferation;0.0170677062497265!GO:0006378;mRNA polyadenylation;0.017183054101584!GO:0030659;cytoplasmic vesicle membrane;0.0172395682843565!GO:0043065;positive regulation of apoptosis;0.0172501980788026!GO:0031902;late endosome membrane;0.017631903972709!GO:0048144;fibroblast proliferation;0.0177299710379469!GO:0048145;regulation of fibroblast proliferation;0.0177299710379469!GO:0000070;mitotic sister chromatid segregation;0.0177870408989381!GO:0043161;proteasomal ubiquitin-dependent protein catabolic process;0.0181908526013437!GO:0007050;cell cycle arrest;0.0183983175004879!GO:0042168;heme metabolic process;0.0183983175004879!GO:0007017;microtubule-based process;0.0184085186152387!GO:0008538;proteasome activator activity;0.0197889487223168!GO:0006354;RNA elongation;0.0199680833950299!GO:0000819;sister chromatid segregation;0.0200279583370427!GO:0006730;one-carbon compound metabolic process;0.0200279583370427!GO:0000030;mannosyltransferase activity;0.0202885914769968!GO:0007243;protein kinase cascade;0.0203658552135318!GO:0046519;sphingoid metabolic process;0.0205409241248143!GO:0043241;protein complex disassembly;0.0212506477230869!GO:0007034;vacuolar transport;0.0212506477230869!GO:0050178;phenylpyruvate tautomerase activity;0.0216901323470211!GO:0016788;hydrolase activity, acting on ester bonds;0.0224976860218759!GO:0045859;regulation of protein kinase activity;0.0225086086631576!GO:0051053;negative regulation of DNA metabolic process;0.0226297797431177!GO:0046365;monosaccharide catabolic process;0.0230909175594146!GO:0016667;oxidoreductase activity, acting on sulfur group of donors;0.0231844868367766!GO:0031903;microbody membrane;0.0233190082772866!GO:0005778;peroxisomal membrane;0.0233190082772866!GO:0006596;polyamine biosynthetic process;0.0234261580996263!GO:0005869;dynactin complex;0.0234261580996263!GO:0019783;small conjugating protein-specific protease activity;0.0234261580996263!GO:0043068;positive regulation of programmed cell death;0.0236451511787198!GO:0032981;mitochondrial respiratory chain complex I assembly;0.0237461025314602!GO:0010257;NADH dehydrogenase complex assembly;0.0237461025314602!GO:0033108;mitochondrial respiratory chain complex assembly;0.0237461025314602!GO:0004860;protein kinase inhibitor activity;0.0238589585178304!GO:0016706;oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, 2-oxoglutarate as one donor, and incorporation of one atom each of oxygen into both donors;0.0242984744320581!GO:0006672;ceramide metabolic process;0.0243764456407168!GO:0044454;nuclear chromosome part;0.0243814764879344!GO:0008250;oligosaccharyl transferase complex;0.0245724657251843!GO:0005853;eukaryotic translation elongation factor 1 complex;0.0247765468089144!GO:0030508;thiol-disulfide exchange intermediate activity;0.0252108621151662!GO:0004576;oligosaccharyl transferase activity;0.0252108621151662!GO:0016790;thiolester hydrolase activity;0.0252957312840324!GO:0003923;GPI-anchor transamidase activity;0.0254703319016507!GO:0016255;attachment of GPI anchor to protein;0.0254703319016507!GO:0042765;GPI-anchor transamidase complex;0.0254703319016507!GO:0030134;ER to Golgi transport vesicle;0.0254967612172517!GO:0000726;non-recombinational repair;0.0255706549726221!GO:0009003;signal peptidase activity;0.0255706549726221!GO:0022411;cellular component disassembly;0.0257920002225658!GO:0030133;transport vesicle;0.0258355704651233!GO:0005732;small nucleolar ribonucleoprotein complex;0.0258359058240107!GO:0017166;vinculin binding;0.0267065940799071!GO:0007346;regulation of progression through mitotic cell cycle;0.0268093978862229!GO:0031529;ruffle organization and biogenesis;0.0268585465988925!GO:0006643;membrane lipid metabolic process;0.02701130352782!GO:0050794;regulation of cellular process;0.0271954210752863!GO:0043189;H4/H2A histone acetyltransferase complex;0.0276110829145186!GO:0006360;transcription from RNA polymerase I promoter;0.0276694886707463!GO:0004843;ubiquitin-specific protease activity;0.0277905848152192!GO:0000077;DNA damage checkpoint;0.0281372359925834!GO:0006417;regulation of translation;0.0285895811237962!GO:0008536;Ran GTPase binding;0.0296369024474758!GO:0005669;transcription factor TFIID complex;0.0296612417021363!GO:0000781;chromosome, telomeric region;0.0296612417021363!GO:0006979;response to oxidative stress;0.0298125848084621!GO:0031123;RNA 3'-end processing;0.0298224758289645!GO:0006356;regulation of transcription from RNA polymerase I promoter;0.0298861113545539!GO:0051059;NF-kappaB binding;0.0301013731855044!GO:0046112;nucleobase biosynthetic process;0.030229235590179!GO:0006376;mRNA splice site selection;0.0302472995069626!GO:0000389;nuclear mRNA 3'-splice site recognition;0.0302472995069626!GO:0006213;pyrimidine nucleoside metabolic process;0.0302523684058791!GO:0005996;monosaccharide metabolic process;0.0303413066651252!GO:0046164;alcohol catabolic process;0.0308299054269989!GO:0005850;eukaryotic translation initiation factor 2 complex;0.0308575054874619!GO:0046128;purine ribonucleoside metabolic process;0.0308575054874619!GO:0042278;purine nucleoside metabolic process;0.0308575054874619!GO:0006220;pyrimidine nucleotide metabolic process;0.031083213271911!GO:0004579;dolichyl-diphosphooligosaccharide-protein glycotransferase activity;0.0314019313068353!GO:0008299;isoprenoid biosynthetic process;0.031966192864417!GO:0003702;RNA polymerase II transcription factor activity;0.0321867135181311!GO:0015036;disulfide oxidoreductase activity;0.0323941168006264!GO:0006769;nicotinamide metabolic process;0.032677470415884!GO:0045926;negative regulation of growth;0.0328474196908302!GO:0019318;hexose metabolic process;0.0330504496367479!GO:0030677;ribonuclease P complex;0.0331255706661459!GO:0045045;secretory pathway;0.0331835238098938!GO:0009066;aspartate family amino acid metabolic process;0.0331835238098938!GO:0001522;pseudouridine synthesis;0.033821854937428!GO:0005774;vacuolar membrane;0.0338926201736423!GO:0003857;3-hydroxyacyl-CoA dehydrogenase activity;0.0339484027386588!GO:0004861;cyclin-dependent protein kinase inhibitor activity;0.0340623064589103!GO:0006368;RNA elongation from RNA polymerase II promoter;0.0342512157982882!GO:0004659;prenyltransferase activity;0.0345160825344732!GO:0032200;telomere organization and biogenesis;0.0345823487802728!GO:0000723;telomere maintenance;0.0345823487802728!GO:0044433;cytoplasmic vesicle part;0.0345823487802728!GO:0019320;hexose catabolic process;0.0348767716513051!GO:0050811;GABA receptor binding;0.0356677350152597!GO:0006518;peptide metabolic process;0.0360538725482566!GO:0005658;alpha DNA polymerase:primase complex;0.0360554525562139!GO:0030127;COPII vesicle coat;0.0361671058570066!GO:0012507;ER to Golgi transport vesicle membrane;0.0361671058570066!GO:0005784;translocon complex;0.0361671058570066!GO:0006541;glutamine metabolic process;0.0370758486528929!GO:0006739;NADP metabolic process;0.0370761176350509!GO:0004448;isocitrate dehydrogenase activity;0.037461949715977!GO:0000792;heterochromatin;0.0375276878124469!GO:0012506;vesicle membrane;0.0381065065347388!GO:0042769;DNA damage response, detection of DNA damage;0.0381065065347388!GO:0000152;nuclear ubiquitin ligase complex;0.0383853448983848!GO:0005777;peroxisome;0.0383853448983848!GO:0042579;microbody;0.0383853448983848!GO:0008173;RNA methyltransferase activity;0.0386424561821818!GO:0035267;NuA4 histone acetyltransferase complex;0.038717684708277!GO:0006783;heme biosynthetic process;0.038717684708277!GO:0016197;endosome transport;0.0392339712189602!GO:0019362;pyridine nucleotide metabolic process;0.039647879306047!GO:0006006;glucose metabolic process;0.039647879306047!GO:0051128;regulation of cellular component organization and biogenesis;0.0403159396664087!GO:0003756;protein disulfide isomerase activity;0.0403868926101058!GO:0016864;intramolecular oxidoreductase activity, transposing S-S bonds;0.0403868926101058!GO:0051716;cellular response to stimulus;0.0408616544327932!GO:0042364;water-soluble vitamin biosynthetic process;0.0410419377109883!GO:0003985;acetyl-CoA C-acetyltransferase activity;0.0423108432235026!GO:0008426;protein kinase C inhibitor activity;0.0423654813425663!GO:0031371;ubiquitin conjugating enzyme complex;0.0423654813425663!GO:0031625;ubiquitin protein ligase binding;0.0427674154163068!GO:0040029;regulation of gene expression, epigenetic;0.0433341536486152!GO:0006644;phospholipid metabolic process;0.0433341536486152!GO:0009225;nucleotide-sugar metabolic process;0.0433341536486152!GO:0030911;TPR domain binding;0.0439329800836172!GO:0005971;ribonucleoside-diphosphate reductase complex;0.0440484461962961!GO:0042026;protein refolding;0.0449169143340024!GO:0016417;S-acyltransferase activity;0.0452312821605321!GO:0004748;ribonucleoside-diphosphate reductase activity;0.0453119534647994!GO:0016728;oxidoreductase activity, acting on CH or CH2 groups, disulfide as acceptor;0.0453119534647994!GO:0008276;protein methyltransferase activity;0.0453161673628616!GO:0008409;5'-3' exonuclease activity;0.045698020302008!GO:0004221;ubiquitin thiolesterase activity;0.0457139135736709!GO:0007040;lysosome organization and biogenesis;0.045827804647369!GO:0018196;peptidyl-asparagine modification;0.045827804647369!GO:0018279;protein amino acid N-linked glycosylation via asparagine;0.045827804647369!GO:0008203;cholesterol metabolic process;0.0458490239445819!GO:0009067;aspartate family amino acid biosynthetic process;0.0458933153972425!GO:0009396;folic acid and derivative biosynthetic process;0.046960265174354!GO:0008156;negative regulation of DNA replication;0.0477486878943334!GO:0030330;DNA damage response, signal transduction by p53 class mediator;0.0478156211576818!GO:0004536;deoxyribonuclease activity;0.0478156211576818!GO:0016791;phosphoric monoester hydrolase activity;0.0478982818088128!GO:0006308;DNA catabolic process;0.0482433604831181!GO:0030518;steroid hormone receptor signaling pathway;0.0490035005811713!GO:0006406;mRNA export from nucleus;0.049015338253122!GO:0001836;release of cytochrome c from mitochondria;0.0493103712844815!GO:0009081;branched chain family amino acid metabolic process;0.0495837424607255 | |||
|sample_id=11892 | |sample_id=11892 | ||
|sample_note= | |sample_note= | ||
| Line 76: | Line 99: | ||
|sample_tissue= | |sample_tissue= | ||
|top_motifs=ARNT_ARNT2_BHLHB2_MAX_MYC_USF1:1.97158083286;PPARG:1.68965928692;E2F1..5:1.67966199956;ESRRA:1.58294403347;RXR{A,B,G}_{NR1H2,PPAR}dimers:1.4522542598;HIF1A:1.43824588767;FOXQ1:1.38065397486;ELK1,4_GABP{A,B1}:1.34732775747;NR5A1,2:1.33602562339;HES1:1.25986406071;PAX1,9:1.02988135225;NKX3-1:0.978248450803;NRF1:0.887920152188;FOXM1:0.884348537475;bHLH_family:0.871135329683;FOXN1:0.865957670402;YY1:0.861405988662;ZNF143:0.738004706452;NFY{A,B,C}:0.733679642513;MYB:0.687639316972;HNF4A_NR2F1,2:0.684852046957;TEF:0.605529987302;SNAI1..3:0.582569899735;HOX{A6,A7,B6,B7}:0.574966970954;PAX8:0.543573419827;ZEB1:0.508627772364;NKX3-2:0.496201286603;TFDP1:0.493340033229;NR6A1:0.481517588115;MYOD1:0.459289736048;PAX5:0.442668523143;TEAD1:0.442586051606;GCM1,2:0.423525520694;VSX1,2:0.389475622695;IKZF1:0.376477086274;ARID5B:0.353780247403;BREu{core}:0.332191981575;ZNF148:0.319520345603;POU1F1:0.317207980766;IRF7:0.310714777451;TBX4,5:0.271004601933;TP53:0.26873595286;EP300:0.250489280567;CREB1:0.248896182391;PAX2:0.227765129236;GFI1:0.215269157246;LEF1_TCF7_TCF7L1,2:0.211024960819;MYBL2:0.197995002462;CDC5L:0.191926170918;PBX1:0.186820548995;RORA:0.184730978375;LHX3,4:0.183411727041;UFEwm:0.170871788033;IKZF2:0.140061836113;RXR{A,B,G}:0.123923594283;HLF:0.119055198379;NFE2L2:0.115695393165;NFE2L1:0.11125011068;PDX1:0.107819549938;FOX{I1,J2}:0.106293062705;EN1,2:0.106147621883;FOXL1:0.101206448215;OCT4_SOX2{dimer}:0.10000242623;NFE2:0.0985478290482;AHR_ARNT_ARNT2:0.0844823590832;HAND1,2:0.0595287959271;FOXD3:0.0508497147381;RFX2..5_RFXANK_RFXAP:0.0490585534442;GTF2A1,2:0.0475534972056;GZF1:0.0375576954817;HOX{A5,B5}:0.0365695227422;ZBTB16:0.0362915173912;PITX1..3:0.0319761205542;HOXA9_MEIS1:0.0317114355225;GFI1B:0.0277019960291;BACH2:0.0229387841186;MTF1:0.0177817422073;STAT5{A,B}:0.0101634298751;HNF1A:-0.00153378691119;ALX4:-0.006104996118;SOX{8,9,10}:-0.0152644940657;CUX2:-0.0268988151906;NR3C1:-0.0440449256764;FOS_FOS{B,L1}_JUN{B,D}:-0.0546286646189;FOX{F1,F2,J1}:-0.0686534999428;ATF5_CREB3:-0.0823173263565;NANOG:-0.103741661666;ZNF423:-0.106473598741;POU3F1..4:-0.114188288101;CDX1,2,4:-0.118526731379;ZNF384:-0.135681311071;PRRX1,2:-0.139334734247;MEF2{A,B,C,D}:-0.145799703451;HSF1,2:-0.155808279918;CEBPA,B_DDIT3:-0.163765873524;MAFB:-0.165276142081;DBP:-0.16866958539;NR1H4:-0.174061411669;NKX6-1,2:-0.174245015059;NKX2-2,8:-0.174269583732;PAX3,7:-0.181347737933;ZBTB6:-0.187129336289;LMO2:-0.205300496007;HOX{A4,D4}:-0.207678130007;STAT2,4,6:-0.219597205945;ZFP161:-0.23443070117;ADNP_IRX_SIX_ZHX:-0.252262639036;POU2F1..3:-0.255519374694;ONECUT1,2:-0.255588434228;NFIL3:-0.265495236732;ELF1,2,4:-0.270188376162;FOSL2:-0.28718082286;BPTF:-0.306836047712;NFKB1_REL_RELA:-0.317780353775;T:-0.326171397789;RBPJ:-0.328425599132;TLX1..3_NFIC{dimer}:-0.336462703511;ESR1:-0.351453542259;TFAP2{A,C}:-0.352861394984;JUN:-0.36107063723;TBP:-0.36865191205;HBP1_HMGB_SSRP1_UBTF:-0.369085073199;HMGA1,2:-0.382025454647;CRX:-0.383293764433;GLI1..3:-0.402438704355;AIRE:-0.406939076255;ATF6:-0.409573699769;ATF4:-0.415649264928;NKX2-3_NKX2-5:-0.416891694037;POU5F1:-0.438985280002;IRF1,2:-0.445080924378;SREBF1,2:-0.446418651443;KLF4:-0.45975878527;EVI1:-0.467348825716;RXRA_VDR{dimer}:-0.47016854561;HIC1:-0.479542929394;TFAP2B:-0.497203247358;GATA6:-0.510087302391;EBF1:-0.526140188521;NKX2-1,4:-0.527770318748;SPIB:-0.529902794412;GTF2I:-0.530981979659;RFX1:-0.532894277167;PAX6:-0.544007390126;FOXP3:-0.547763769092;TFCP2:-0.554506905759;ALX1:-0.55472912494;REST:-0.562809786174;FOXP1:-0.564680636345;PAX4:-0.579719201154;SOX5:-0.582127654899;MED-1{core}:-0.583537370733;EGR1..3:-0.600557219694;SOX2:-0.605570154791;SOX17:-0.63229827808;SPI1:-0.677413074399;RUNX1..3:-0.68273855223;GATA4:-0.696158807243;MTE{core}:-0.703308164752;TAL1_TCF{3,4,12}:-0.721417847944;NHLH1,2:-0.724139713592;ZIC1..3:-0.72560894613;ETS1,2:-0.739186416767;POU6F1:-0.742207764025;SP1:-0.748906617871;AR:-0.770380579085;FOXA2:-0.784218580306;SRF:-0.79703082471;TFAP4:-0.813353112976;DMAP1_NCOR{1,2}_SMARC:-0.85348453153;TOPORS:-0.897930723111;NFATC1..3:-0.967775195887;MAZ:-0.981662608773;ZNF238:-0.983524709386;MYFfamily:-0.988110706052;SMAD1..7,9:-0.998110566936;ATF2:-1.02480761464;XCPE1{core}:-1.0265168785;FOX{D1,D2}:-1.03910848171;RREB1:-1.08591484195;HMX1:-1.12134173461;PRDM1:-1.14031654145;NFIX:-1.14401473001;FOXO1,3,4:-1.15680433704;XBP1:-1.16787429588;MZF1:-1.21651485734;STAT1,3:-1.22897122701;TGIF1:-1.31926749007;PATZ1:-1.40345636777;TLX2:-1.67091037947;NANOG{mouse}:-1.68391633036;SPZ1:-1.78961199005 | |top_motifs=ARNT_ARNT2_BHLHB2_MAX_MYC_USF1:1.97158083286;PPARG:1.68965928692;E2F1..5:1.67966199956;ESRRA:1.58294403347;RXR{A,B,G}_{NR1H2,PPAR}dimers:1.4522542598;HIF1A:1.43824588767;FOXQ1:1.38065397486;ELK1,4_GABP{A,B1}:1.34732775747;NR5A1,2:1.33602562339;HES1:1.25986406071;PAX1,9:1.02988135225;NKX3-1:0.978248450803;NRF1:0.887920152188;FOXM1:0.884348537475;bHLH_family:0.871135329683;FOXN1:0.865957670402;YY1:0.861405988662;ZNF143:0.738004706452;NFY{A,B,C}:0.733679642513;MYB:0.687639316972;HNF4A_NR2F1,2:0.684852046957;TEF:0.605529987302;SNAI1..3:0.582569899735;HOX{A6,A7,B6,B7}:0.574966970954;PAX8:0.543573419827;ZEB1:0.508627772364;NKX3-2:0.496201286603;TFDP1:0.493340033229;NR6A1:0.481517588115;MYOD1:0.459289736048;PAX5:0.442668523143;TEAD1:0.442586051606;GCM1,2:0.423525520694;VSX1,2:0.389475622695;IKZF1:0.376477086274;ARID5B:0.353780247403;BREu{core}:0.332191981575;ZNF148:0.319520345603;POU1F1:0.317207980766;IRF7:0.310714777451;TBX4,5:0.271004601933;TP53:0.26873595286;EP300:0.250489280567;CREB1:0.248896182391;PAX2:0.227765129236;GFI1:0.215269157246;LEF1_TCF7_TCF7L1,2:0.211024960819;MYBL2:0.197995002462;CDC5L:0.191926170918;PBX1:0.186820548995;RORA:0.184730978375;LHX3,4:0.183411727041;UFEwm:0.170871788033;IKZF2:0.140061836113;RXR{A,B,G}:0.123923594283;HLF:0.119055198379;NFE2L2:0.115695393165;NFE2L1:0.11125011068;PDX1:0.107819549938;FOX{I1,J2}:0.106293062705;EN1,2:0.106147621883;FOXL1:0.101206448215;OCT4_SOX2{dimer}:0.10000242623;NFE2:0.0985478290482;AHR_ARNT_ARNT2:0.0844823590832;HAND1,2:0.0595287959271;FOXD3:0.0508497147381;RFX2..5_RFXANK_RFXAP:0.0490585534442;GTF2A1,2:0.0475534972056;GZF1:0.0375576954817;HOX{A5,B5}:0.0365695227422;ZBTB16:0.0362915173912;PITX1..3:0.0319761205542;HOXA9_MEIS1:0.0317114355225;GFI1B:0.0277019960291;BACH2:0.0229387841186;MTF1:0.0177817422073;STAT5{A,B}:0.0101634298751;HNF1A:-0.00153378691119;ALX4:-0.006104996118;SOX{8,9,10}:-0.0152644940657;CUX2:-0.0268988151906;NR3C1:-0.0440449256764;FOS_FOS{B,L1}_JUN{B,D}:-0.0546286646189;FOX{F1,F2,J1}:-0.0686534999428;ATF5_CREB3:-0.0823173263565;NANOG:-0.103741661666;ZNF423:-0.106473598741;POU3F1..4:-0.114188288101;CDX1,2,4:-0.118526731379;ZNF384:-0.135681311071;PRRX1,2:-0.139334734247;MEF2{A,B,C,D}:-0.145799703451;HSF1,2:-0.155808279918;CEBPA,B_DDIT3:-0.163765873524;MAFB:-0.165276142081;DBP:-0.16866958539;NR1H4:-0.174061411669;NKX6-1,2:-0.174245015059;NKX2-2,8:-0.174269583732;PAX3,7:-0.181347737933;ZBTB6:-0.187129336289;LMO2:-0.205300496007;HOX{A4,D4}:-0.207678130007;STAT2,4,6:-0.219597205945;ZFP161:-0.23443070117;ADNP_IRX_SIX_ZHX:-0.252262639036;POU2F1..3:-0.255519374694;ONECUT1,2:-0.255588434228;NFIL3:-0.265495236732;ELF1,2,4:-0.270188376162;FOSL2:-0.28718082286;BPTF:-0.306836047712;NFKB1_REL_RELA:-0.317780353775;T:-0.326171397789;RBPJ:-0.328425599132;TLX1..3_NFIC{dimer}:-0.336462703511;ESR1:-0.351453542259;TFAP2{A,C}:-0.352861394984;JUN:-0.36107063723;TBP:-0.36865191205;HBP1_HMGB_SSRP1_UBTF:-0.369085073199;HMGA1,2:-0.382025454647;CRX:-0.383293764433;GLI1..3:-0.402438704355;AIRE:-0.406939076255;ATF6:-0.409573699769;ATF4:-0.415649264928;NKX2-3_NKX2-5:-0.416891694037;POU5F1:-0.438985280002;IRF1,2:-0.445080924378;SREBF1,2:-0.446418651443;KLF4:-0.45975878527;EVI1:-0.467348825716;RXRA_VDR{dimer}:-0.47016854561;HIC1:-0.479542929394;TFAP2B:-0.497203247358;GATA6:-0.510087302391;EBF1:-0.526140188521;NKX2-1,4:-0.527770318748;SPIB:-0.529902794412;GTF2I:-0.530981979659;RFX1:-0.532894277167;PAX6:-0.544007390126;FOXP3:-0.547763769092;TFCP2:-0.554506905759;ALX1:-0.55472912494;REST:-0.562809786174;FOXP1:-0.564680636345;PAX4:-0.579719201154;SOX5:-0.582127654899;MED-1{core}:-0.583537370733;EGR1..3:-0.600557219694;SOX2:-0.605570154791;SOX17:-0.63229827808;SPI1:-0.677413074399;RUNX1..3:-0.68273855223;GATA4:-0.696158807243;MTE{core}:-0.703308164752;TAL1_TCF{3,4,12}:-0.721417847944;NHLH1,2:-0.724139713592;ZIC1..3:-0.72560894613;ETS1,2:-0.739186416767;POU6F1:-0.742207764025;SP1:-0.748906617871;AR:-0.770380579085;FOXA2:-0.784218580306;SRF:-0.79703082471;TFAP4:-0.813353112976;DMAP1_NCOR{1,2}_SMARC:-0.85348453153;TOPORS:-0.897930723111;NFATC1..3:-0.967775195887;MAZ:-0.981662608773;ZNF238:-0.983524709386;MYFfamily:-0.988110706052;SMAD1..7,9:-0.998110566936;ATF2:-1.02480761464;XCPE1{core}:-1.0265168785;FOX{D1,D2}:-1.03910848171;RREB1:-1.08591484195;HMX1:-1.12134173461;PRDM1:-1.14031654145;NFIX:-1.14401473001;FOXO1,3,4:-1.15680433704;XBP1:-1.16787429588;MZF1:-1.21651485734;STAT1,3:-1.22897122701;TGIF1:-1.31926749007;PATZ1:-1.40345636777;TLX2:-1.67091037947;NANOG{mouse}:-1.68391633036;SPZ1:-1.78961199005 | ||
|xref= | |||
|zenbu_report=https://fantom.gsc.riken.jp/zenbu/reports/#miRNA_expression_atlas_human;search_select_hide=table111:FF:11892-125E2;search_select_hide=table117:FF:11892-125E2 | |||
}} | }} | ||
Latest revision as of 18:27, 4 June 2020
| Name: | Hep-2 cells treated with Streptococci strain 5448, biol_rep3 |
|---|---|
| Species: | Human (Homo sapiens) |
| Library ID: | CNhs13497 |
| Sample type: | cell lines |
| Genomic View: | UCSC |
| RefEX: | Specific genes |
| CAGEd-oPOSSUM: | link |
| ZENBU report : | link |
| Additional information | ||||||||||||||||||||||||||||
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Sample information
RNA information
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| CAGE Accession numbers | ||||||||||||||||||||||||||||||||||||||||||||||
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| Download raw sequence, BAM & CTSS | ||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
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Relative expression to median (log10)
Transcription factors with enriched expression in this sampleRanked list of transcription factor promoter expression in this sample relative to the median expression in the FANTOM5 collection is shown. Value is log10 transformed.
Co-expression clusters with enriched expression in this sampleRanked list of co-expression cluster expression in this sample relative to the median expression in the FANTOM5 collection is shown. Value is log10 transformed. <br>Analyst:NA <br><br>link to dataset.<br>data
Repeat families with enriched expression in this sample<b>Summary:</b>Ranked list of repeat family expression in this sample relative tothe median expression in the FANTOM5 collection is shown. Value is log10transformed.<br><b>Analyst:</b>NA<br><br>link to dataset.<br>data
TFBS(DNA)motifs over-represented in proximal region of promoters active in this sample
JASPAR motifs<b>Summary:</b>Association of JASPAR motif to the promoter expression in thissample. Pearson's correlation between the number of TFBSs estimated byusing the position-weight matrix for each promoter and its expression isexpressed as Z-score by taking the ones based on random position-weightmatrix, and the tail probability of the normal distribution correspondingto the Z-score is taken as the resulting P-value. Lower P-value indicatesmore (non-random) association of the motif to promoter expression<br><b>Analyst:</b> Michiel de Hoon <br><br><br>link to dataset.<br>data
library id: CNhs13497
FANTOM5 phase1 novel unique motifs<b>Summary:</b>Association of the 169 novel and unique motifs discovered in FANTOM5 phase1 in this sample. Among the de-novo motifs discovered by DMF, HOMER,ChIPMunk, and ScanAll, only novel motifs are selected after comparison with known motif sets, and their clustering based on MACRO-APE resulted in169 novel and unique motifs. Their association to the promoter expression is evaluated in the same way to the JASPAR motif above<br><b>Analyst:</b> Michiel de Hoon <br><br><br>link to dataset.<br>data
library id: CNhs13497
| Novel motif | Logo | P-value |
|---|---|---|
| 1 | 1 | 0.11 |
| 10 | 10 | 0.0839 |
| 100 | 100 | 0.029 |
| 101 | 101 | 0.243 |
| 102 | 102 | 0.998 |
| 103 | 103 | 0.757 |
| 104 | 104 | 0.765 |
| 105 | 105 | 0.0672 |
| 106 | 106 | 0.00759 |
| 107 | 107 | 0.0741 |
| 108 | 108 | 0.744 |
| 109 | 109 | 0.00345 |
| 11 | 11 | 0.797 |
| 110 | 110 | 0.685 |
| 111 | 111 | 0.413 |
| 112 | 112 | 0.234 |
| 113 | 113 | 0.00236 |
| 114 | 114 | 0.81 |
| 115 | 115 | 0.962 |
| 116 | 116 | 0.487 |
| 117 | 117 | 0.226 |
| 118 | 118 | 0.225 |
| 119 | 119 | 0.923 |
| 12 | 12 | 0.417 |
| 120 | 120 | 0.0603 |
| 121 | 121 | 0.388 |
| 122 | 122 | 0.0491 |
| 123 | 123 | 0.16 |
| 124 | 124 | 0.829 |
| 125 | 125 | 0.871 |
| 126 | 126 | 0.71 |
| 127 | 127 | 0.204 |
| 128 | 128 | 8.72361e-5 |
| 129 | 129 | 0.402 |
| 13 | 13 | 1.51618e-4 |
| 130 | 130 | 0.457 |
| 131 | 131 | 0.625 |
| 132 | 132 | 0.58 |
| 133 | 133 | 0.0942 |
| 134 | 134 | 0.73 |
| 135 | 135 | 0.065 |
| 136 | 136 | 0.00359 |
| 137 | 137 | 0.236 |
| 138 | 138 | 0.662 |
| 139 | 139 | 0.124 |
| 14 | 14 | 0.352 |
| 140 | 140 | 0.345 |
| 141 | 141 | 0.401 |
| 142 | 142 | 0.669 |
| 143 | 143 | 0.296 |
| 144 | 144 | 0.355 |
| 145 | 145 | 0.267 |
| 146 | 146 | 0.917 |
| 147 | 147 | 0.716 |
| 148 | 148 | 0.917 |
| 149 | 149 | 0.287 |
| 15 | 15 | 0.681 |
| 150 | 150 | 0.898 |
| 151 | 151 | 0.689 |
| 152 | 152 | 0.307 |
| 153 | 153 | 0.65 |
| 154 | 154 | 0.347 |
| 155 | 155 | 0.522 |
| 156 | 156 | 0.0192 |
| 157 | 157 | 0.0799 |
| 158 | 158 | 0.209 |
| 159 | 159 | 0.291 |
| 16 | 16 | 0.857 |
| 160 | 160 | 0.675 |
| 161 | 161 | 0.962 |
| 162 | 162 | 0.532 |
| 163 | 163 | 0.181 |
| 164 | 164 | 0.0363 |
| 165 | 165 | 0.982 |
| 166 | 166 | 0.0121 |
| 167 | 167 | 0.106 |
| 168 | 168 | 0.287 |
| 169 | 169 | 0.514 |
| 17 | 17 | 0.783 |
| 18 | 18 | 0.166 |
| 19 | 19 | 0.61 |
| 2 | 2 | 0.402 |
| 20 | 20 | 0.0999 |
| 21 | 21 | 0.531 |
| 22 | 22 | 0.782 |
| 23 | 23 | 0.00235 |
| 24 | 24 | 0.539 |
| 25 | 25 | 0.175 |
| 26 | 26 | 0.763 |
| 27 | 27 | 0.707 |
| 28 | 28 | 0.89 |
| 29 | 29 | 0.0295 |
| 3 | 3 | 0.505 |
| 30 | 30 | 0.465 |
| 31 | 31 | 0.438 |
| 32 | 32 | 0.0558 |
| 33 | 33 | 0.236 |
| 34 | 34 | 0.154 |
| 35 | 35 | 0.793 |
| 36 | 36 | 0.156 |
| 37 | 37 | 0.675 |
| 38 | 38 | 0.908 |
| 39 | 39 | 0.937 |
| 4 | 4 | 0.281 |
| 40 | 40 | 0.0331 |
| 41 | 41 | 0.0961 |
| 42 | 42 | 0.957 |
| 43 | 43 | 0.367 |
| 44 | 44 | 0.081 |
| 45 | 45 | 0.153 |
| 46 | 46 | 0.477 |
| 47 | 47 | 0.504 |
| 48 | 48 | 0.497 |
| 49 | 49 | 0.238 |
| 5 | 5 | 0.299 |
| 50 | 50 | 0.909 |
| 51 | 51 | 0.531 |
| 52 | 52 | 0.273 |
| 53 | 53 | 0.136 |
| 54 | 54 | 0.326 |
| 55 | 55 | 0.0623 |
| 56 | 56 | 0.98 |
| 57 | 57 | 0.459 |
| 58 | 58 | 0.843 |
| 59 | 59 | 0.599 |
| 6 | 6 | 0.585 |
| 60 | 60 | 0.37 |
| 61 | 61 | 0.102 |
| 62 | 62 | 0.779 |
| 63 | 63 | 0.69 |
| 64 | 64 | 0.958 |
| 65 | 65 | 0.252 |
| 66 | 66 | 0.37 |
| 67 | 67 | 0.831 |
| 68 | 68 | 0.663 |
| 69 | 69 | 0.943 |
| 7 | 7 | 0.016 |
| 70 | 70 | 0.101 |
| 71 | 71 | 0.083 |
| 72 | 72 | 0.797 |
| 73 | 73 | 0.739 |
| 74 | 74 | 0.143 |
| 75 | 75 | 0.196 |
| 76 | 76 | 0.237 |
| 77 | 77 | 0.94 |
| 78 | 78 | 0.256 |
| 79 | 79 | 0.504 |
| 8 | 8 | 0.145 |
| 80 | 80 | 0.0447 |
| 81 | 81 | 0.428 |
| 82 | 82 | 0.0237 |
| 83 | 83 | 0.706 |
| 84 | 84 | 0.481 |
| 85 | 85 | 0.00701 |
| 86 | 86 | 0.777 |
| 87 | 87 | 0.00902 |
| 88 | 88 | 0.893 |
| 89 | 89 | 0.782 |
| 9 | 9 | 0.495 |
| 90 | 90 | 0.0105 |
| 91 | 91 | 0.0182 |
| 92 | 92 | 0.0777 |
| 93 | 93 | 0.276 |
| 94 | 94 | 0.503 |
| 95 | 95 | 0.0344 |
| 96 | 96 | 0.586 |
| 97 | 97 | 0.944 |
| 98 | 98 | 0.8 |
| 99 | 99 | 0.516 |
de novo motifs identified by HOMER in promoters active in this sample<b>Summary:</b>The result of HOMER in this sample is shown.<br><b>Analyst:</b>NA <br>
library id: CNhs13497
FANTOM5 (FF) ontology
Direct parent terms
is_a relathionship
EFO:0002091 biological replicate
FF:0011133 human Hep-2 cells treated with Streptococci strain 5448 sample
Ancestor terms (non development)<b>Summary:</b>Connected ontology terms with is_a, part_of or located_in relationship <br><b>Analyst:</b> Hideya Kawaji<br><br>link to source data<br>data
CL: Cell type
0000000 (cell), 0000000 (cell)
0000003 (native cell)
0000548 (animal cell)
0000066 (epithelial cell)
0000255 (eukaryotic cell)
DOID: Disease
4 (disease)
162 (cancer)
14566 (disease of cellular proliferation)
0050687 (cell type cancer)
305 (carcinoma)
UBERON: Anatomy
0000468 (multi-cellular organism)
0001737 (larynx)
0000064 (organ part)
0004119 (endoderm-derived structure)
0000062 (organ)
0000061 (anatomical structure)
0000465 (material anatomical entity)
0000063 (organ segment)
0000477 (anatomical cluster)
0000467 (anatomical system)
0001062 (anatomical entity)
0000480 (anatomical group)
0000072 (segment of respiratory tract)
0010317 (germ layer / neural crest derived structure)
0000065 (respiratory tract)
0001004 (respiratory system)
0001557 (upper respiratory tract)
FF: FANTOM5
0000102 (sample by type)
0000003 (cell line sample)
0000210 (human sample)
0000101 (sample by species)
0000001 (sample)
0000625 (experimental infection sample)
0000350 (experimentally modified sample)
0000632 (group A streptococci treatment sample)
0104978 (HEp-2 cell sample)
0000638 (Streptococcus strain 5448 treatment sample)
0100297 (carcinoma cell line sample)
0101120 (epithelial cell line sample)
0011133 (human Hep-2 cells treated with Streptococci strain 5448 sample)
Ancestor terms (development)<b>Summary:</b>Connected ontology terms with develops_from, derives_from or preceded_by relationship <br><b>Analyst:</b> Hideya Kawaji <br><br>link to source data<br>data
UBERON:0008947 (respiratory primordium)
UBERON:0002532 (epiblast (generic))
UBERON:0006595 (presumptive endoderm)
UBERON:0010316 (germ layer / neural crest)
