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Coexpression cluster:C2647: Difference between revisions

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{{Coexpression_clusters
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|coexpression_dpi_cluster_scores_median=0.

Latest revision as of 12:10, 17 September 2013


Full id: C2647_Adipocyte_Preadipocyte_tenocyte_Osteoblast_basal_Mesenchymal_Olfactory



Phase1 CAGE Peaks

Hg19::chr22:43023683..43023702,-p@chr22:43023683..43023702
-
Hg19::chr22:43024232..43024253,-p5@CYB5R3
Hg19::chr22:43026936..43026976,-p4@CYB5R3
Hg19::chr22:43026982..43027003,-p10@CYB5R3


Enriched pathways on this co-expression cluster<b>Summary:</b><br>Canonical pathway gene sets were compiled from Reactome, Wikipathways and KEGG. For the major signaling pathways, the transcriptionally-regulated genes (downstream targets) were obtained from Netpath. Combined, the canonical pathways and downstream targets totaled 489 human gene sets. The corresponding M. musculus gene sets were inferred by homology using the HomoloGene database. Enrichment for each of the canonical 489 pathways and gene sets included in the co-expression cluster was assessed by the hypergeometric probability. The resulting P values were also then adjusted by the Benjamini-Hochberg method for multiple comparisons.<br><b>Analyst: </b>Emmanuel Dimont<br><br>link to source dataset<br>data

No results for this coexpression

Enriched Gene Ontology terms on this co-expression cluster<b>Summary:</b> Results for GOStat analysis on co-expressed clusters. Each cluster with promoters mapping to at least two different genes was analysed with GOStat (PMID: 14962934) with default parameter. <br><b>Analyst:</b> Erik Arner<br><br>link to source dataset<br>data

No GOStat results

Enriched sample ontology terms on this co-expression cluster<b>Summary:</b>To summarize promoter activities (expression profile of a TSS region) across ~1000 samples, we performed enrichment analysis based on FANTOM5 Sample Ontology (FF ontology). The question here is “in which type of samples the promoter is more active”. To answer this question, we compared expressions (TPMs) in the samples associated with a sample ontology term and the rest of the samples by using the Mann-Whitney rank sum test. To summarize ontologies enriched in this co-expression cluster, we ran the same analysis on an averaged expression profile of all promoters that make up. <b>Analyst:</b> Hideya Kawaji <br><br>links to source dataset<br><br>cell_data<br>uberon_data<br><br>

Cell Type
Ontology termp-valuen
fibroblast2.39e-1476
somatic cell6.52e-14588
mesodermal cell1.21e-10121
somatic stem cell8.74e-09433
fat cell1.05e-0815
multi fate stem cell1.20e-08427
embryonic cell4.48e-08250
stem cell6.33e-08441
contractile cell7.65e-0859
animal cell1.12e-07679
eukaryotic cell1.12e-07679
smooth muscle cell2.21e-0743
smooth muscle myoblast2.21e-0743
muscle precursor cell2.48e-0758
myoblast2.48e-0758
multi-potent skeletal muscle stem cell2.48e-0758
Uber Anatomy
Ontology termp-valuen
epithelial vesicle4.65e-1178
trunk mesenchyme5.56e-11122
mesoderm1.17e-10315
mesoderm-derived structure1.17e-10315
presumptive mesoderm1.17e-10315
mesenchyme8.55e-10160
entire embryonic mesenchyme8.55e-10160
vasculature1.53e-0978
vascular system1.53e-0978
multi-cellular organism2.79e-09656
epithelial tube3.51e-09117
somite8.95e-0971
presomitic mesoderm8.95e-0971
presumptive segmental plate8.95e-0971
dermomyotome8.95e-0971
trunk paraxial mesoderm8.95e-0971
vessel9.11e-0968
dense mesenchyme tissue9.80e-0973
paraxial mesoderm1.07e-0872
presumptive paraxial mesoderm1.07e-0872
surface structure3.56e-0899
multilaminar epithelium5.00e-0883
integument6.28e-0846
integumental system6.28e-0846
anatomical system6.64e-08624
anatomical group8.90e-08625
splanchnic layer of lateral plate mesoderm2.66e-0783
epithelial tube open at both ends3.01e-0759
blood vessel3.01e-0759
blood vasculature3.01e-0759
vascular cord3.01e-0759
skeletal muscle tissue6.19e-0762
striated muscle tissue6.19e-0762
myotome6.19e-0762
unilaminar epithelium7.54e-07148
circulatory system8.10e-07112
muscle tissue8.59e-0764
musculature8.59e-0764
musculature of body8.59e-0764


Overrepresented TFBS (DNA) motifs on this co-expression cluster<b>Summary:</b>The values shown are the p-values for overrepresentation of the motif in this coexpression cluster. So a small p-value means a strong overrepresentation. <b>Analyst:</b> Michiel de Hoon <br><br>link to source data <br> Novel motifs <br>data <br><br> Jaspar motifs <br>data

Novel motifs



JASPAR motifs

Motifs-log10(p-value)
MA0003.10.0938548
MA0004.10.71247
MA0006.10.532262
MA0007.10.6918
MA0009.11.20602
MA0014.10.0695829
MA0017.11.41335
MA0019.10.873355
MA0024.11.09684
MA0025.11.34373
MA0027.12.83281
MA0028.11.35734
MA0029.11.11704
MA0030.11.10506
MA0031.11.03735
MA0038.10.824639
MA0040.11.12314
MA0041.10.732902
MA0042.10.697662
MA0043.11.20635
MA0046.11.19471
MA0048.10.25531
MA0050.10.69864
MA0051.10.820063
MA0052.11.12718
MA0055.10.791759
MA0056.10
MA0057.10.69331
MA0058.10.605914
MA0059.10.604454
MA0060.10.393285
MA0061.13.49299
MA0063.10
MA0066.13.20189
MA0067.11.53181
MA0068.10.313194
MA0069.11.19071
MA0070.11.17908
MA0071.11.8408
MA0072.11.1744
MA0073.12.83685
MA0074.10.819248
MA0076.10.623864
MA0077.11.16637
MA0078.10.926725
MA0081.10.604638
MA0083.11.21381
MA0084.11.72172
MA0087.11.17185
MA0088.11.02755
MA0089.10
MA0090.10.640115
MA0091.10.715356
MA0092.10.673508
MA0093.10.535768
MA0095.10
MA0098.10
MA0100.10.83965
MA0101.12.29123
MA0103.10.521546
MA0105.11.90157
MA0106.10.869173
MA0107.12.98058
MA0108.21.03412
MA0109.10
MA0111.10.655276
MA0113.10.886811
MA0114.11.98562
MA0115.11.45393
MA0116.10.457606
MA0117.11.24497
MA0119.10.586221
MA0122.11.27173
MA0124.11.41151
MA0125.11.32534
MA0130.10
MA0131.10.94608
MA0132.10
MA0133.10
MA0135.11.23748
MA0136.10.832277
MA0139.10.344952
MA0140.10.779643
MA0141.10.602484
MA0142.11.00381
MA0143.10.887001
MA0144.10.430413
MA0145.10.195821
MA0146.10.221129
MA0147.10.46175
MA0148.10.739888
MA0149.10.769072
MA0062.20.353589
MA0035.20.778873
MA0039.20.483275
MA0138.20.928035
MA0002.20.379056
MA0137.20.558189
MA0104.20.392359
MA0047.20.856092
MA0112.20.551048
MA0065.21.09513
MA0150.10.633493
MA0151.10
MA0152.10.78681
MA0153.11.30799
MA0154.11.21162
MA0155.10.180766
MA0156.10.560797
MA0157.10.97481
MA0158.10
MA0159.12.03616
MA0160.10.756582
MA0161.10
MA0162.10.309472
MA0163.10.539587
MA0164.10.90014
MA0080.20.535868
MA0018.22.02192
MA0099.20.7872
MA0079.20.327251
MA0102.21.75932
MA0258.11.07498
MA0259.10.471671
MA0442.10



ENCODE TF ChIP-seq peak enrichment analysis<b>Summary:</b> For each TF and each co-expression cluster, the number of promoters with ENCODE TF ChIP signal was compared with the rest of promoters from the robust set using Fisher's exact test. Clusters with significant ChIP enrichment (q <= 0.05) after Benjamini-Hochberg correction were retained. <br><b>Analyst:</b> Erik Arner<br><br>link to source dataset<br><br>data

No analysis results for this cluster

Relative expression of the co-expression cluster<b>Summary:</b>Co-expression clusters are compared against FANTOM5 samples to obtain relative expression. <br><b>Analyst:</b>NA<br><br>link to data source<br> data

This analysis result is provided for C0 - C305 clusters.

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