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MCL coexpression mm9:1306: Difference between revisions

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{{MCL_coexpression_mm9|gostat_on_MCL_coexpression=GO:0004839;ubiquitin activating enzyme activity;0.0157752026064506;!GO:0008641;small protein activating enzyme activity;0.0157752026064506;!}}
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activating enzyme activity;0.0157752026064506;!GO:0008641;small protein activating enzyme activity;0.0157752026064506;!|ontology_enrichment_celltype=|ontology_enrichment_disease=|ontology_enrichment_uberon=UBERON:0004177!8.53e-14!29;UBERON:0005057!8.53e-14!29;UBERON:0002390!2.56e-12!45;UBERON:0003061!2.56e-12!45;UBERON:0002193!8.45e-12!48;UBERON:0002405!8.45e-12!48;UBERON:0000077!1.12e-11!35;UBERON:0001041!2.91e-11!80;UBERON:0003408!2.19e-10!24;UBERON:0002370!3.10e-10!23;UBERON:0000974!3.10e-10!23;UBERON:0004807!3.10e-10!23;UBERON:0005058!3.10e-10!23;UBERON:0003351!3.10e-10!23;UBERON:0009113!3.10e-10!23;UBERON:0003295!3.10e-10!23;UBERON:0009722!3.10e-10!23;UBERON:0005562!3.10e-10!23;UBERON:0007690!3.10e-10!23;UBERON:0006562!1.93e-09!24;UBERON:0001557!1.93e-09!24;UBERON:0001042!1.93e-09!24;UBERON:0008814!1.93e-09!24;UBERON:0009145!1.93e-09!24;UBERON:0000949!9.99e-09!72;UBERON:0000475!7.30e-08!150;UBERON:0001004!7.99e-08!42;UBERON:0005911!9.02e-08!69;UBERON:0000065!1.25e-07!41;UBERON:0002368!1.41e-07!60;UBERON:0002530!1.81e-07!65;UBERON:0000072!1.83e-07!27;UBERON:0003929!5.17e-07!55;UBERON:0003081!5.88e-07!87|tfbs_overrepresentation_for_novel_motifs=0.491922,0.473747,0.464605,0.535892,0.346849,0.550971,0.645383,0.691572,0.257202,0.0835344,0.599767,0.632897,0.247704,0.6581,0.364314,0,0.856992,0.338549,0.656199,0.143775,1.09054,0.108444,0.657163,0.345236,0.472505,0.686615,0.63639,0.572827,0.394364,0.181062,0.558142,0.960397,0.336199,0.204204,0.364821,0.144368,0.326478,0.629145,0.303703,0.27383,0.342638,0.56353,0.327433,0.366415,0.161543,0.524258,0.77511,0.589246,0.284064,0.397446,0.839084,0.714419,0.517905,1.10437,1.12205,0.66551,0.406788,0.619643,0.21472,0.663395,0.939962,0.724164,0.269393,0.827522,0.677043,0.869046,1.2599,1.61148,0.935192,1.46355,0.444872,0.253541,0.11437,1.156,0.208101,0.19692,0.204132,0.763395,0.922432,0.430551,0.254777,0.874787,0.722675,0.240896,1.03903,0.0539203,0.220054,1.02367,0.780154,1.77427,1.33021,1.04409,0.973447,1.66204,0.2995,0.281222,0.685716,0.976308,0.775372,0.938145,0.326561,0.960112,1.08669,0.839694,0.838613,0.563071,0.8998,0.585058,0.435642,0.428007,0.484547,1.0885,0.431734,0.605144,1.33732,0.340765,0.0704207,0.53982,0.858327,0.322606,1.16147,0.805995,0.688501,0.762461,1.39185,0.926209,0.65384,0.966541,1.25836,0.356163,1.06946,0.52828,1.2285,0.679647,1.35909,0.106956,0.500709,0.564999,1.30952,2.14327,1.74232,1.26465,0.700956,0.971067,0.831964,0.564002,0.778321,2.10357,0.503174,0.348692,0.183562,0.0987301,1.10596,1.42796,0.678689,1.18867,0.71546,0.376898,1.22669,0.500417,1.31911,1.03816,0.926663,0.482185,0.82857,0.671017,0.325308,0.63125,0.30995|tfbs_overrepresentation_jaspar=MA0003.1;0.00973143,MA0004.1;0.536396,MA0006.1;0.359699,MA0007.1;0.52077,MA0009.1;0.987341,MA0014.1;0.12867,MA0017.1;1.00628,MA0019.1;0.800946,MA0024.1;0.942716,MA0025.1;1.22395,MA0027.1;2.64231,MA0028.1;0.370592,MA0029.1;0.920529,MA0030.1;0.927235,MA0031.1;0.890871,MA0038.1;0.686534,MA0040.1;1.00009,MA0041.1;0.457338,MA0042.1;0.443591,MA0043.1;1.08567,MA0046.1;1.02391,MA0048.1;0.161427,MA0050.1;0.57678,MA0051.1;0.695779,MA0052.1;1.00829,MA0055.1;0.0585191,MA0056.1;0,MA0057.1;0.895081,MA0058.1;0.436487,MA0059.1;0.449345,MA0060.1;0.275911,MA0061.1;0.307097,MA0063.1;0,MA0066.1;0.675169,MA0067.1;1.33603,MA0068.1;0.911705,MA0069.1;1.00864,MA0070.1;0.998765,MA0071.1;0.575909,MA0072.1;0.990133,MA0073.1;0.00638767,MA0074.1;0.638014,MA0076.1;0.407465,MA0077.1;0.968053,MA0078.1;0.729877,MA0081.1;1.19271,MA0083.1;1.08487,MA0084.1;1.66561,MA0087.1;1.04109,MA0088.1;0.358337,MA0089.1;0,MA0090.1;0.500693,MA0091.1;0.55008,MA0092.1;0.501022,MA0093.1;0.379257,MA0095.1;0,MA0098.1;0,MA0100.1;0.626021,MA0101.1;1.16089,MA0103.1;0.398766,MA0105.1;0.199622,MA0106.1;0.737893,MA0107.1;0.392331,MA0108.2;0.824407,MA0109.1;0,MA0111.1;0.515457,MA0113.1;0.708789,MA0114.1;1.49046,MA0115.1;1.08851,MA0116.1;0.944657,MA0117.1;1.05576,MA0119.1;0.459301,MA0122.1;1.07591,MA0124.1;1.28237,MA0125.1;1.20757,MA0130.1;0,MA0131.1;0.796279,MA0132.1;0,MA0133.1;0,MA0135.1;1.1226,MA0136.1;0.658622,MA0139.1;0.243463,MA0140.1;0.625902,MA0141.1;0.419361,MA0142.1;0.876028,MA0143.1;0.725672,MA0144.1;0.307873,MA0145.1;0.119202,MA0146.1;0.353523,MA0147.1;0.320675,MA0148.1;1.3627,MA0149.1;0.464445,MA0062.2;0.204999,MA0035.2;0.630778,MA0039.2;0.0823004,MA0138.2;0.788113,MA0002.2;0.689262,MA0137.2;0.416331,MA0104.2;0.261255,MA0047.2;0.685741,MA0112.2;0.37938,MA0065.2;1.24784,MA0150.1;0.520653,MA0151.1;0,MA0152.1;0.685852,MA0153.1;1.13945,MA0154.1;0.480757,MA0155.1;0.822245,MA0156.1;0.406559,MA0157.1;0.843181,MA0158.1;0,MA0159.1;0.331229,MA0160.1;0.556423,MA0161.1;0,MA0162.1;0.0465447,MA0163.1;0.372305,MA0164.1;0.658997,MA0080.2;1.01893,MA0018.2;0.669032,MA0099.2;0.781628,MA0079.2;0.221916,MA0102.2;1.7182,MA0258.1;0.290587,MA0259.1;0.309517,MA0442.1;0}}

Latest revision as of 16:43, 17 September 2013


Phase1 CAGE Peaks

 Short description
Mm9::chr11:87570427..87570431,+p2@Mir142
Mm9::chr1:167615652..167615656,-p@chr1:167615652..167615656
-
Mm9::chr5:86539268..86539274,+p@chr5:86539268..86539274
+
Mm9::chr6:145070282..145070315,+p1@Lrmp
Mm9::chr6:145072003..145072005,+p@chr6:145072003..145072005
+
Mm9::chr6:145111646..145111650,+p@chr6:145111646..145111650
+


Enriched pathways on this co-expression cluster<b>Summary:</b><br>Canonical pathway gene sets were compiled from Reactome, Wikipathways and KEGG. For the major signaling pathways, the transcriptionally-regulated genes (downstream targets) were obtained from Netpath. Combined, the canonical pathways and downstream targets totaled 489 human gene sets. The corresponding M. musculus gene sets were inferred by homology using the HomoloGene database. Enrichment for each of the canonical 489 pathways and gene sets included in the co-expression cluster was assessed by the hypergeometric probability. The resulting P values were also then adjusted by the Benjamini-Hochberg method for multiple comparisons.<br><b>Analyst: </b>Emmanuel Dimont<br><br>link to source dataset<br>data

GO IDGO nameFDR corrected p-value
GO:0004839ubiquitin activating enzyme activity0.0157752026064506
GO:0008641small protein activating enzyme activity0.0157752026064506



Relative expression of the co-expression cluster over median <br>Analyst:




Enriched sample ontology terms on this co-expression cluster<b>Summary:</b>To summarize promoter activities (expression profile of a TSS region) across ~1000 samples, we performed enrichment analysis based on FANTOM5 Sample Ontology (FF ontology). The question here is “in which type of samples the promoter is more active”. To answer this question, we compared expressions (TPMs) in the samples associated with a sample ontology term and the rest of the samples by using the Mann-Whitney rank sum test. To summarize ontologies enriched in this co-expression cluster, we ran the same analysis on an averaged expression profile of all promoters that make up. <b>Analyst:</b> Hideya Kawaji <br><br>links to source dataset<br><br><br>uberon_data<br><br>

Uber Anatomy
Ontology termp-valuen
hemopoietic organ8.53e-1429
immune organ8.53e-1429
hematopoietic system2.56e-1245
blood island2.56e-1245
hemolymphoid system8.45e-1248
immune system8.45e-1248
mixed endoderm/mesoderm-derived structure1.12e-1135
foregut2.91e-1180
gland of gut2.19e-1024
thymus3.10e-1023
neck3.10e-1023
respiratory system epithelium3.10e-1023
hemolymphoid system gland3.10e-1023
pharyngeal epithelium3.10e-1023
thymic region3.10e-1023
pharyngeal gland3.10e-1023
entire pharyngeal arch endoderm3.10e-1023
thymus primordium3.10e-1023
early pharyngeal endoderm3.10e-1023
pharynx1.93e-0924
upper respiratory tract1.93e-0924
chordate pharynx1.93e-0924
pharyngeal arch system1.93e-0924
pharyngeal region of foregut1.93e-0924
endocrine system9.99e-0972
organism subdivision7.30e-08150
respiratory system7.99e-0842
endo-epithelium9.02e-0869
respiratory tract1.25e-0741
endocrine gland1.41e-0760
gland1.81e-0765
segment of respiratory tract1.83e-0727
gut epithelium5.17e-0755
lateral plate mesoderm5.88e-0787


TFBS overrepresentation<b>Summary:</b>The values shown are the p-values for overrepresentation of the motif in this coexpression cluster. So a small p-value means a strong overrepresentation. <b>Analyst:</b> Michiel de Hoon <br><br>link to source data <br> Novel motifs <br>data <br><br> Jaspar motifs <br>data

Novel motifs




JASPAR motifs


Motifs-log10(p-value)
MA0003.10.00973143
MA0004.10.536396
MA0006.10.359699
MA0007.10.52077
MA0009.10.987341
MA0014.10.12867
MA0017.11.00628
MA0019.10.800946
MA0024.10.942716
MA0025.11.22395
MA0027.12.64231
MA0028.10.370592
MA0029.10.920529
MA0030.10.927235
MA0031.10.890871
MA0038.10.686534
MA0040.11.00009
MA0041.10.457338
MA0042.10.443591
MA0043.11.08567
MA0046.11.02391
MA0048.10.161427
MA0050.10.57678
MA0051.10.695779
MA0052.11.00829
MA0055.10.0585191
MA0056.10
MA0057.10.895081
MA0058.10.436487
MA0059.10.449345
MA0060.10.275911
MA0061.10.307097
MA0063.10
MA0066.10.675169
MA0067.11.33603
MA0068.10.911705
MA0069.11.00864
MA0070.10.998765
MA0071.10.575909
MA0072.10.990133
MA0073.10.00638767
MA0074.10.638014
MA0076.10.407465
MA0077.10.968053
MA0078.10.729877
MA0081.11.19271
MA0083.11.08487
MA0084.11.66561
MA0087.11.04109
MA0088.10.358337
MA0089.10
MA0090.10.500693
MA0091.10.55008
MA0092.10.501022
MA0093.10.379257
MA0095.10
MA0098.10
MA0100.10.626021
MA0101.11.16089
MA0103.10.398766
MA0105.10.199622
MA0106.10.737893
MA0107.10.392331
MA0108.20.824407
MA0109.10
MA0111.10.515457
MA0113.10.708789
MA0114.11.49046
MA0115.11.08851
MA0116.10.944657
MA0117.11.05576
MA0119.10.459301
MA0122.11.07591
MA0124.11.28237
MA0125.11.20757
MA0130.10
MA0131.10.796279
MA0132.10
MA0133.10
MA0135.11.1226
MA0136.10.658622
MA0139.10.243463
MA0140.10.625902
MA0141.10.419361
MA0142.10.876028
MA0143.10.725672
MA0144.10.307873
MA0145.10.119202
MA0146.10.353523
MA0147.10.320675
MA0148.11.3627
MA0149.10.464445
MA0062.20.204999
MA0035.20.630778
MA0039.20.0823004
MA0138.20.788113
MA0002.20.689262
MA0137.20.416331
MA0104.20.261255
MA0047.20.685741
MA0112.20.37938
MA0065.21.24784
MA0150.10.520653
MA0151.10
MA0152.10.685852
MA0153.11.13945
MA0154.10.480757
MA0155.10.822245
MA0156.10.406559
MA0157.10.843181
MA0158.10
MA0159.10.331229
MA0160.10.556423
MA0161.10
MA0162.10.0465447
MA0163.10.372305
MA0164.10.658997
MA0080.21.01893
MA0018.20.669032
MA0099.20.781628
MA0079.20.221916
MA0102.21.7182
MA0258.10.290587
MA0259.10.309517
MA0442.10
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