MCL coexpression mm9:617: Difference between revisions
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{{MCL_coexpression_mm9 | {{MCL_coexpression_mm9|coexpression_dpi_cluster_scores_mean=-0.00566105209370606,-0.0318454690256817,-0.0182735718347087,-0.0318454690256817,-0.0171495921893905,-0.0114670365336689,-0.0126235581679738,-0.0318454690256817,-0.0270783674348844,-0.0318454690256817,-0.0261256584849588,-0.0318454690256817,-0.0318454690256817,-0.0288123459365134,-0.021439976642769,-0.0318454690256817,-0.0318454690256817,-0.0265448279128523,-0.0318454690256817,-0.0318454690256817,0.319907514969602,-0.0318454690256817,-0.0318454690256817,-0.0117506448241768,-0.0318454690256817,-0.0318454690256817,-0.0318454690256817,-0.0247834119770814,-0.0201876501386138,-0.0114665635173195,-0.00614216790261999,-0.0318454690256817,-0.0318454690256817,-0.0318454690256817,-0.0318454690256817,-0.0318454690256817,-0.0251215047696112,-0.0318454690256817,-0.0318454690256817,-0.0318454690256817,-0.0318454690256817,-0.0130041479330472,-0.0175224954508958,-0.0318454690256817,-0.0248561397308746,-0.0257466841928727,0.0535674409537565,0.00512467301535393,0.0336693353453249,0.058528238589905,0.0213274135876544,-0.0318454690256817,-0.026231968841186,-0.0318454690256817,-0.0318454690256817,-0.0318454690256817,-0.0318454690256817,-0.0061968427650591,0.0632766914307918,0.0403758920315139,-0.0140781990856438,-0.0318454690256817,-0.0318454690256817,-0.0318454690256817,-0.0318454690256817,-0.0318454690256817,-0.00536942063047558,0.00766944792998779,-0.00591590685320469,-0.022679113399615,-0.0318454690256817,0.0505932836028927,0.0957627014084885,-0.00762118198714421,-0.0219081397531094,-0.00825176184665173,0.134416969044102,0.319044028901699,0.279001061626592,0.0691677265313335,0.0414134041128075,0.0243401845601459,0.29437937493462,0.139310643511969,0.250831088114575,0.159372357060422,0.148148646696067,0.0867113447899311,-0.0140490325532315,-0.00452397258359013,0.00522860088996059,-0.0318454690256817,-0.0130703130940997,-0.0318454690256817,-0.0318454690256817,-0.0318454690256817,0.0737166427059776,-0.0261500053074247,-0.0318454690256817,-0.0318454690256817,-1.49956562956414e-05,-0.0318454690256817,-0.0318454690256817,-0.0318454690256817,-0.0318454690256817,-0.0318454690256817,-0.0318454690256817,0.0556208688494552,-0.00611840478863683,0.0791651199659732,0.0336500026061029,0.0538290035404862,0.0241710382418128,0.0589921321247832,0.10501352682871,0.046217444428617,-0.0158564107150293,0.0419879799707028,0.0752117865102407,0.112758429982028,0.091455668837156,0.136136951914916,0.0364046072033415,0.953352929481542,1.01237728745348,0.0427579273753009,-0.0318454690256817,-0.0318454690256817,-0.0318454690256817,0.312841760140995,0.457843024448206,0.0728173868978296,0.524140526280546,0.523155113574809,0.369756601344405,0.409076274780001,0.144640051765646,0.116431446178977,0.146315715127915,0.736195172065172,0.034165236261972,0.0257182777805362,0.0379098475951119,0.177012044711535,0.256563030784096,0.3475852334454,0.366248997051143,0.820675634031191,-0.0106506549832754,0.0263821881981638,0.079043466579272,0.0642299957046219,0.156729487517351,0.151207443990819,0.158965692515121,0.0565909456057824,-0.0318454690256817,-0.0318454690256817,-0.0318454690256817,-0.018220048633532,-0.0165954253561368,-0.0138692569785371,-0.00877545142776705,0.00216749670360105,-0.00769563626416761,-0.0180239898718999,0.00255882577353531,0.021608524361546,0.0352678386878195,0.0635511844778617,0.0551455753629362,0.0536818120461771,0.0821212951996916,0.0842913130164691,0.401662605967698,0.185556311862682,-0.0318454690256817,0.00276332236195026,0.0459675686415226,0.0670122696347449,0.0848271511226099,0.0507276345849092,0.083014353234238,0.071649949262632,0.0590796876576837,0.0425124029906904,0.0626384766309161,0.0643086063195758,0.0585965347461221,0.0518011117702489,0.0699957991013425,0.0382172305840532,-0.00134986566595757,0.0381237517547122,0.065488261457763,0.0673272444052382,0.0465655250922804,0.0388067879826429,0.0246149762504614,0.0244569776948313,0.0300009682374738,0.000169202114912454,-0.0224490813510071,-0.0171582838927648,-0.0198464773103926,-0.0245048689265497,-0.0318454690256817,-0.0318454690256817,-0.0318454690256817,-0.0318454690256817,-0.016242689428128,-0.014285341315735,0.0494286624183914,-0.0318454690256817,0.0117231406397877,-0.00739419802987243,-0.0199021071901648,-0.0318454690256817,-0.00819381623465562,0.00328464108578637,0.0168395965335194,7.37501638904403e-05,-0.0179176131042862,0.0235071583917926,0.00782041074620479,0.0086825081109425,0.0401045862564609,0.0333443565173249,0.0870992934304146,0.0183388241421944,-0.0203152418020225,0.00552159398807834,-0.0318454690256817,-0.00520453086848799,-0.0318454690256817,0.0122500080849891,0.319804811497863,0.366386746175218,-0.0318454690256817,0.0915951469043961,0.0154009685730529,0.0260579734964627,0.0392073696909349,0.00435986640525843,0.018526635296769,-0.00959623280605456,-0.0103798253388171,-0.0318454690256817,0.00129256776152383,0.533375707916519,0.0909965383621414,0.0755531809616676,0.09680634757473,0.0655656959131067,-0.0012720841876416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at_on_MCL_coexpression=GO:0032344;regulation of aldosterone metabolic process;0.00598257820632225;16531!GO:0060082;eye blink reflex;0.00598257820632225;16531!GO:0045794;negative regulation of cell volume;0.00598257820632225;16531!GO:0019228;generation of action potential;0.00598257820632225;16531!GO:0060072;large conductance calcium-activated potassium channel activity;0.00598257820632225;16531!GO:0032341;aldosterone metabolic process;0.00747740333140966;16531!GO:0008212;mineralocorticoid metabolic process;0.00747740333140966;16531!GO:0060083;smooth muscle contraction involved in micturition;0.00747740333140966;16531!GO:0045475;locomotor rhythm;0.00747740333140966;16531!GO:0046541;saliva secretion;0.00747740333140966;16531!GO:0060087;relaxation of vascular smooth muscle;0.00747740333140966;16531!GO:0032350;regulation of hormone metabolic process;0.00747740333140966;16531!GO:0006884;regulation of cell volume;0.00920245371152283;16531!GO:0048512;circadian behavior;0.00934572995597631;16531!GO:0060073;micturition;0.00934572995597631;16531!GO:0045986;negative regulation of smooth muscle contraction;0.00934572995597631;16531!GO:0043195;terminal button;0.00996823240522129;16531!GO:0045932;negative regulation of muscle contraction;0.00996823240522129;16531!GO:0019218;regulation of steroid metabolic process;0.0104660705212238;16531!GO:0007622;rhythmic behavior;0.0104660705212238;16531!GO:0060004;reflex;0.0113910171841284;16531!GO:0033267;axon part;0.0122317288545561;16531!GO:0007589;fluid secretion;0.0137025647441517;16531!GO:0015269;calcium-activated potassium channel activity;0.0137025647441517;16531!GO:0022600;digestive system process;0.0144304228663273;16531!GO:0022839;ion gated channel activity;0.0144304228663273;16531!GO:0005227;calcium activated cation channel activity;0.0144304228663273;16531!GO:0042311;vasodilation;0.0144304228663273;16531!GO:0003014;renal system process;0.0144304228663273;16531!GO:0006940;regulation of smooth muscle contraction;0.0169357831169092;16531!GO:0019216;regulation of lipid metabolic process;0.0183156324409287;16531!GO:0051260;protein homooligomerization;0.0190146248393245;16531!GO:0001666;response to hypoxia;0.0190146248393245;16531!GO:0007628;adult walking behavior;0.0193331386871007;16531!GO:0042491;auditory receptor cell differentiation;0.0196333582008793;16531!GO:0006939;smooth muscle contraction;0.0215741766630153;16531!GO:0060113;inner ear receptor cell differentiation;0.0217972456042262;16531!GO:0051241;negative regulation of multicellular organismal process;0.0220695770245465;16531!GO:0007623;circadian rhythm;0.0220695770245465;16531!GO:0051259;protein oligomerization;0.0220695770245465;16531!GO:0050885;neuromuscular process controlling balance;0.0220695770245465;16531!GO:0042490;mechanoreceptor differentiation;0.0220695770245465;16531!GO:0006937;regulation of muscle contraction;0.0220695770245465;16531!GO:0003018;vascular process in circulatory system;0.0220695770245465;16531!GO:0035150;regulation of tube size;0.0220695770245465;16531!GO:0050880;regulation of blood vessel size;0.0220695770245465;16531!GO:0007586;digestion;0.0254034203893136;16531!GO:0008344;adult locomotory behavior;0.0255820679322074;16531!GO:0042391;regulation of membrane potential;0.0255820679322074;16531!GO:0050905;neuromuscular process;0.0280473105145699;16531!GO:0016324;apical plasma membrane;0.0286643199364667;16531!GO:0008076;voltage-gated potassium channel complex;0.0309732709122608;16531!GO:0030534;adult behavior;0.0342297737221806;16531!GO:0030424;axon;0.0342297737221806;16531!GO:0044463;cell projection part;0.0365964280469895;16531!GO:0050878;regulation of body fluid levels;0.0365964280469895;16531!GO:0048839;inner ear development;0.0365964280469895;16531!GO:0048469;cell maturation;0.0380122815999812;16531!GO:0043583;ear development;0.0382285833979674;16531!GO:0045177;apical part of cell;0.0382285833979674;16531!GO:0042445;hormone metabolic process;0.038619253433346;16531!GO:0003012;muscle system process;0.038619253433346;16531!GO:0005249;voltage-gated potassium channel activity;0.038619253433346;16531!GO:0006936;muscle contraction;0.038619253433346;16531!GO:0021700;developmental maturation;0.0414892090984599;16531!GO:0007605;sensory perception of sound;0.0414892090984599;16531!GO:0008015;blood circulation;0.0415752100295672;16531!GO:0003013;circulatory system process;0.0415752100295672;16531!GO:0050954;sensory perception of mechanical stimulus;0.0418306613280087;16531!GO:0045211;postsynaptic membrane;0.0460676981297058;16531!GO:0030955;potassium ion binding;0.0460676981297058;16531!GO:0022843;voltage-gated cation channel activity;0.0472339476899721;16531!GO:0043005;neuron projection;0.0472339476899721;16531!GO:0044456;synapse part;0.0483364338596647;16531!GO:0005267;potassium channel activity;0.0483364338596647;16531!GO:0006461;protein complex 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| |||
|coexpression_dpi_cluster_scores_median=0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0.257056954190279,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0.0837385476634741,0,0,0,0,0.268265648242696,0.140471483716244,0,0.0190094117790312,0,0.264238928079949,0.145470913910986,0.24486099132265,0.145177779261325,0.0783604393173399,0.0371154675793343,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0.0234784353458152,0,0,0,0,0,0.03048532897689,0.0482820047261801,0,0,0.00203244474419316,0,0.0651189800845078,0,0,0,0.837394991652415,0.922937812069745,0,0,0,0,0.265541541797723,0.402281617672439,0.0467415735589952,0.488690613285645,0.443773638492404,0.389965922625323,0.390018921364508,0.0613144345794207,0.0509235292940968,0,0.593693241804618,0,0,0,0.138207433048781,0.188729419737229,0.324137036422789,0.282812357304689,0.761341716438561,0,0,0,0,0,0,0.0812688455295622,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0.0660154575426048,0,0,0,0,0.288576182241383,0.116844694267823,0,0,0,0,0.0263214775189998,0,0,0,0,0,0,0,0,0,0,0,0,0.0234910315133595,0,0.040250349638994,0,0.0147194505648231,0,0,0.013722283512511,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0.0321269055488328,0,0,0,0,0,0,0,0.255936214892323,0.243898642715919,0,0.00046172880201073,0,0,0,0,0,0,0,0,0,0.571449189726263,0,0,0,0,0,0,0,0.037813311251513,0,0,0,0,0.0198022793348323,0,0,0,0.12724725138213,0,0,0,0,0.0534664588774845,0.0661577744756082,0,0,0,0.122614493264369,0.0331417600494206,0,0.037447345818524,0,0,0,0.24833528381516,0,0,0,0,0,0,0,0,0,0,0,0,0.0849373898696927,0.0412290086072516,0,0,0.017244733229267,0,0,0,0,0,0,0,0.0263777085807213,0.0338991055318041,0.0698792936134432,0.100511416252052,0.117400313648829,0.19381699336556,0.109925980570702,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0.379358589281386,0.368482786744713,0.51072496385796,0.460186694697268,0.300699880676714,0.244374584202533,0.29754841187768,0.325073160817734,0.443392237382217,0.487285649470539,0,0,0.0501869017813935,0.0472542065752338,0,0,0.0750151328830584,0.081359932135904,0,0,0,0.0750453505157095,0.0388749848471105,0.0523284672130554,0.0794275503022596,0,0.0690741623162511,0.0766073954291401,0,0.0858532545793502,0.0824587512862088,0.0709519923534245,0,0.108051585821735,0.0748964051866952,0.0830715518132696,0.104181599639904,0.0940886679317074,0.0521766646345615,0,0.0486884105045233,0.0408018333703219,0,0.0625582350728301,0.0383032227056179,0.0968441960560167,0.091291089277545,0,0.070344611177821,0,0 | |||
|gostat_on_MCL_coexpression=GO:0032344;regulation of aldosterone metabolic process;0.00598257820632225;16531!GO:0060082;eye blink reflex;0.00598257820632225;16531!GO:0045794;negative regulation of cell volume;0.00598257820632225;16531!GO:0019228;generation of action potential;0.00598257820632225;16531!GO:0060072;large conductance calcium-activated potassium channel activity;0.00598257820632225;16531!GO:0032341;aldosterone metabolic process;0.00747740333140966;16531!GO:0008212;mineralocorticoid metabolic process;0.00747740333140966;16531!GO:0060083;smooth muscle contraction involved in micturition;0.00747740333140966;16531!GO:0045475;locomotor rhythm;0.00747740333140966;16531!GO:0046541;saliva secretion;0.00747740333140966;16531!GO:0060087;relaxation of vascular smooth muscle;0.00747740333140966;16531!GO:0032350;regulation of hormone metabolic process;0.00747740333140966;16531!GO:0006884;regulation of cell volume;0.00920245371152283;16531!GO:0048512;circadian behavior;0.00934572995597631;16531!GO:0060073;micturition;0.00934572995597631;16531!GO:0045986;negative regulation of smooth muscle contraction;0.00934572995597631;16531!GO:0043195;terminal button;0.00996823240522129;16531!GO:0045932;negative regulation of muscle contraction;0.00996823240522129;16531!GO:0019218;regulation of steroid metabolic process;0.0104660705212238;16531!GO:0007622;rhythmic behavior;0.0104660705212238;16531!GO:0060004;reflex;0.0113910171841284;16531!GO:0033267;axon part;0.0122317288545561;16531!GO:0007589;fluid secretion;0.0137025647441517;16531!GO:0015269;calcium-activated potassium channel activity;0.0137025647441517;16531!GO:0022600;digestive system process;0.0144304228663273;16531!GO:0022839;ion gated channel activity;0.0144304228663273;16531!GO:0005227;calcium activated cation channel activity;0.0144304228663273;16531!GO:0042311;vasodilation;0.0144304228663273;16531!GO:0003014;renal system process;0.0144304228663273;16531!GO:0006940;regulation of smooth muscle contraction;0.0169357831169092;16531!GO:0019216;regulation of lipid metabolic process;0.0183156324409287;16531!GO:0051260;protein homooligomerization;0.0190146248393245;16531!GO:0001666;response to hypoxia;0.0190146248393245;16531!GO:0007628;adult walking behavior;0.0193331386871007;16531!GO:0042491;auditory receptor cell differentiation;0.0196333582008793;16531!GO:0006939;smooth muscle contraction;0.0215741766630153;16531!GO:0060113;inner ear receptor cell differentiation;0.0217972456042262;16531!GO:0051241;negative regulation of multicellular organismal process;0.0220695770245465;16531!GO:0007623;circadian rhythm;0.0220695770245465;16531!GO:0051259;protein oligomerization;0.0220695770245465;16531!GO:0050885;neuromuscular process controlling balance;0.0220695770245465;16531!GO:0042490;mechanoreceptor differentiation;0.0220695770245465;16531!GO:0006937;regulation of muscle contraction;0.0220695770245465;16531!GO:0003018;vascular process in circulatory system;0.0220695770245465;16531!GO:0035150;regulation of tube size;0.0220695770245465;16531!GO:0050880;regulation of blood vessel size;0.0220695770245465;16531!GO:0007586;digestion;0.0254034203893136;16531!GO:0008344;adult locomotory behavior;0.0255820679322074;16531!GO:0042391;regulation of membrane potential;0.0255820679322074;16531!GO:0050905;neuromuscular process;0.0280473105145699;16531!GO:0016324;apical plasma membrane;0.0286643199364667;16531!GO:0008076;voltage-gated potassium channel complex;0.0309732709122608;16531!GO:0030534;adult behavior;0.0342297737221806;16531!GO:0030424;axon;0.0342297737221806;16531!GO:0044463;cell projection part;0.0365964280469895;16531!GO:0050878;regulation of body fluid levels;0.0365964280469895;16531!GO:0048839;inner ear development;0.0365964280469895;16531!GO:0048469;cell maturation;0.0380122815999812;16531!GO:0043583;ear development;0.0382285833979674;16531!GO:0045177;apical part of cell;0.0382285833979674;16531!GO:0042445;hormone metabolic process;0.038619253433346;16531!GO:0003012;muscle system process;0.038619253433346;16531!GO:0005249;voltage-gated potassium channel activity;0.038619253433346;16531!GO:0006936;muscle contraction;0.038619253433346;16531!GO:0021700;developmental maturation;0.0414892090984599;16531!GO:0007605;sensory perception of sound;0.0414892090984599;16531!GO:0008015;blood circulation;0.0415752100295672;16531!GO:0003013;circulatory system process;0.0415752100295672;16531!GO:0050954;sensory perception of mechanical stimulus;0.0418306613280087;16531!GO:0045211;postsynaptic membrane;0.0460676981297058;16531!GO:0030955;potassium ion binding;0.0460676981297058;16531!GO:0022843;voltage-gated cation channel activity;0.0472339476899721;16531!GO:0043005;neuron projection;0.0472339476899721;16531!GO:0044456;synapse part;0.0483364338596647;16531!GO:0005267;potassium channel activity;0.0483364338596647;16531!GO:0006461;protein complex assembly;0.0488653389425182;16531! | |||
|ontology_enrichment_celltype= | |||
|ontology_enrichment_disease= | |||
|ontology_enrichment_uberon=UBERON:0002346!8.13e-18!64;UBERON:0003075!8.13e-18!64;UBERON:0007284!8.13e-18!64;UBERON:0000073!3.67e-16!54;UBERON:0001049!6.20e-16!52;UBERON:0005068!6.20e-16!52;UBERON:0006241!6.20e-16!52;UBERON:0007135!6.20e-16!52;UBERON:0010371!1.69e-15!73;UBERON:0003056!2.49e-14!49;UBERON:0000955!3.14e-14!47;UBERON:0006238!3.14e-14!47;UBERON:0002616!2.43e-13!46;UBERON:0002021!1.74e-11!10;UBERON:0000411!1.74e-11!10;UBERON:0001950!1.74e-11!10;UBERON:0002020!2.06e-11!34;UBERON:0004121!2.87e-11!95;UBERON:0000924!2.87e-11!95;UBERON:0006601!2.87e-11!95;UBERON:0003080!3.98e-11!40;UBERON:0001017!8.84e-11!73;UBERON:0002780!2.15e-10!39;UBERON:0001890!2.15e-10!39;UBERON:0006240!2.15e-10!39;UBERON:0001016!3.55e-10!75;UBERON:0010314!3.57e-10!92;UBERON:0003528!1.06e-09!29;UBERON:0002791!1.06e-09!29;UBERON:0001893!1.06e-09!29;UBERON:0002619!4.74e-08!17;UBERON:0000956!4.38e-07!21;UBERON:0001869!4.38e-07!21;UBERON:0000203!4.38e-07!21 | |||
|tfbs_overrepresentation_for_novel_motifs=0.267173,0.409645,0.686572,0.303186,0.1565,0.315748,0.396495,0.0908011,0.0967611,0.336879,0.357058,0.385627,0.304329,1.05028,0.974258,0,0.587245,0.459418,0.279039,0.143041,0.215242,0.0948826,0.406794,0.917766,0.251585,0.432737,0.265362,0.334131,0.191143,0.766158,0.321757,0.683831,0.14899,0.234079,0.169391,0.0172637,1.39042,0.382372,0.126724,0.107198,0.153518,0.870859,0.0186013,0.508662,0.283915,0.293566,0.512146,0.34807,0.169751,1.68948,0.570705,0.457464,0.736781,0.82076,0.837732,1.06445,0.581069,0.977003,0.912284,0.412262,0.664611,0.46618,1.68413,0.560059,0.424276,0.598412,0.970969,1.3158,0.660133,1.17005,0.229771,0.0945081,0.102623,0.870406,0.883633,0.222652,0.0658238,1.2527,0.648171,0.218647,0.316038,0.60374,0.464847,0.293128,0.758319,4.3544,3.49902,0.198381,0.516731,1.47691,1.03946,0.763136,0.696137,0.16091,1.27589,0.11194,0.622881,0.698838,0.512384,0.379245,0.438441,0.683562,0.803823,0.571268,0.57027,0.3259,0.627019,0.344504,0.222586,0.216685,0.261228,0.805555,0.219561,0.361667,1.04639,0.463309,1.39764,0.826326,0.58848,0.43155,0.875675,0.540309,0.434408,0.500675,1.09972,0.651709,0.403884,0.689622,0.969481,0.49047,0.787341,0.296885,0.940498,0.426575,1.06766,0.231689,0.274293,0.327523,1.01927,1.84381,1.44523,0.975592,0.445463,0.693891,0.564145,0.326684,0.515065,1.80426,0.276297,4.46106,0.201988,2.768,0.822286,0.115938,0.425729,0.901933,0.458393,0.178202,0.73227,0.274055,1.02862,0.757491,0.652135,0.25933,0.561023,0.418964,0.436256,0.384198,2.09567 | |||
}} |
Latest revision as of 15:36, 17 September 2013
Phase1 CAGE Peaks
Short description | |
---|---|
Mm9::chr14:24823506..24823522,- | p2@Kcnma1 |
Mm9::chr15:39325197..39325201,+ | p@chr15:39325197..39325201 + |
Mm9::chr2:164821483..164821487,+ | p@chr2:164821483..164821487 + |
Mm9::chr2:77358766..77358770,- | p@chr2:77358766..77358770 - |
Mm9::chr2:77654650..77654685,- | p3@Zfp385b |
Mm9::chr2:77654793..77654805,- | p7@Zfp385b |
Mm9::chr2:77654815..77654872,- | p2@Zfp385b |
Mm9::chr5:148770934..148770945,+ | p@chr5:148770934..148770945 + |
Mm9::chr5:34562809..34562811,- | p@chr5:34562809..34562811 - |
Mm9::chr7:82344162..82344165,- | p@chr7:82344162..82344165 - |
Mm9::chr9:40183798..40183848,- | p12@Gramd1b |
Mm9::chr9:40184415..40184432,- | p27@Gramd1b |
Enriched pathways on this co-expression cluster<b>Summary:</b><br>Canonical pathway gene sets were compiled from Reactome, Wikipathways and KEGG. For the major signaling pathways, the transcriptionally-regulated genes (downstream targets) were obtained from Netpath. Combined, the canonical pathways and downstream targets totaled 489 human gene sets. The corresponding M. musculus gene sets were inferred by homology using the HomoloGene database. Enrichment for each of the canonical 489 pathways and gene sets included in the co-expression cluster was assessed by the hypergeometric probability. The resulting P values were also then adjusted by the Benjamini-Hochberg method for multiple comparisons.<br><b>Analyst: </b>Emmanuel Dimont<br><br>link to source dataset<br>data
GO ID | GO name | FDR corrected p-value |
---|---|---|
GO:0032344 | regulation of aldosterone metabolic process | 0.00598257820632225 |
GO:0060082 | eye blink reflex | 0.00598257820632225 |
GO:0045794 | negative regulation of cell volume | 0.00598257820632225 |
GO:0019228 | generation of action potential | 0.00598257820632225 |
GO:0060072 | large conductance calcium-activated potassium channel activity | 0.00598257820632225 |
GO:0032341 | aldosterone metabolic process | 0.00747740333140966 |
GO:0008212 | mineralocorticoid metabolic process | 0.00747740333140966 |
GO:0060083 | smooth muscle contraction involved in micturition | 0.00747740333140966 |
GO:0045475 | locomotor rhythm | 0.00747740333140966 |
GO:0046541 | saliva secretion | 0.00747740333140966 |
GO:0060087 | relaxation of vascular smooth muscle | 0.00747740333140966 |
GO:0032350 | regulation of hormone metabolic process | 0.00747740333140966 |
GO:0006884 | regulation of cell volume | 0.00920245371152283 |
GO:0048512 | circadian behavior | 0.00934572995597631 |
GO:0060073 | micturition | 0.00934572995597631 |
GO:0045986 | negative regulation of smooth muscle contraction | 0.00934572995597631 |
GO:0043195 | terminal button | 0.00996823240522129 |
GO:0045932 | negative regulation of muscle contraction | 0.00996823240522129 |
GO:0019218 | regulation of steroid metabolic process | 0.0104660705212238 |
GO:0007622 | rhythmic behavior | 0.0104660705212238 |
GO:0060004 | reflex | 0.0113910171841284 |
GO:0033267 | axon part | 0.0122317288545561 |
GO:0007589 | fluid secretion | 0.0137025647441517 |
GO:0015269 | calcium-activated potassium channel activity | 0.0137025647441517 |
GO:0022600 | digestive system process | 0.0144304228663273 |
GO:0022839 | ion gated channel activity | 0.0144304228663273 |
GO:0005227 | calcium activated cation channel activity | 0.0144304228663273 |
GO:0042311 | vasodilation | 0.0144304228663273 |
GO:0003014 | renal system process | 0.0144304228663273 |
GO:0006940 | regulation of smooth muscle contraction | 0.0169357831169092 |
GO:0019216 | regulation of lipid metabolic process | 0.0183156324409287 |
GO:0051260 | protein homooligomerization | 0.0190146248393245 |
GO:0001666 | response to hypoxia | 0.0190146248393245 |
GO:0007628 | adult walking behavior | 0.0193331386871007 |
GO:0042491 | auditory receptor cell differentiation | 0.0196333582008793 |
GO:0006939 | smooth muscle contraction | 0.0215741766630153 |
GO:0060113 | inner ear receptor cell differentiation | 0.0217972456042262 |
GO:0051241 | negative regulation of multicellular organismal process | 0.0220695770245465 |
GO:0007623 | circadian rhythm | 0.0220695770245465 |
GO:0051259 | protein oligomerization | 0.0220695770245465 |
GO:0050885 | neuromuscular process controlling balance | 0.0220695770245465 |
GO:0042490 | mechanoreceptor differentiation | 0.0220695770245465 |
GO:0006937 | regulation of muscle contraction | 0.0220695770245465 |
GO:0003018 | vascular process in circulatory system | 0.0220695770245465 |
GO:0035150 | regulation of tube size | 0.0220695770245465 |
GO:0050880 | regulation of blood vessel size | 0.0220695770245465 |
GO:0007586 | digestion | 0.0254034203893136 |
GO:0008344 | adult locomotory behavior | 0.0255820679322074 |
GO:0042391 | regulation of membrane potential | 0.0255820679322074 |
GO:0050905 | neuromuscular process | 0.0280473105145699 |
GO:0016324 | apical plasma membrane | 0.0286643199364667 |
GO:0008076 | voltage-gated potassium channel complex | 0.0309732709122608 |
GO:0030534 | adult behavior | 0.0342297737221806 |
GO:0030424 | axon | 0.0342297737221806 |
GO:0044463 | cell projection part | 0.0365964280469895 |
GO:0050878 | regulation of body fluid levels | 0.0365964280469895 |
GO:0048839 | inner ear development | 0.0365964280469895 |
GO:0048469 | cell maturation | 0.0380122815999812 |
GO:0043583 | ear development | 0.0382285833979674 |
GO:0045177 | apical part of cell | 0.0382285833979674 |
GO:0042445 | hormone metabolic process | 0.038619253433346 |
GO:0003012 | muscle system process | 0.038619253433346 |
GO:0005249 | voltage-gated potassium channel activity | 0.038619253433346 |
GO:0006936 | muscle contraction | 0.038619253433346 |
GO:0021700 | developmental maturation | 0.0414892090984599 |
GO:0007605 | sensory perception of sound | 0.0414892090984599 |
GO:0008015 | blood circulation | 0.0415752100295672 |
GO:0003013 | circulatory system process | 0.0415752100295672 |
GO:0050954 | sensory perception of mechanical stimulus | 0.0418306613280087 |
GO:0045211 | postsynaptic membrane | 0.0460676981297058 |
GO:0030955 | potassium ion binding | 0.0460676981297058 |
GO:0022843 | voltage-gated cation channel activity | 0.0472339476899721 |
GO:0043005 | neuron projection | 0.0472339476899721 |
GO:0044456 | synapse part | 0.0483364338596647 |
GO:0005267 | potassium channel activity | 0.0483364338596647 |
GO:0006461 | protein complex assembly | 0.0488653389425182 |
Relative expression of the co-expression cluster over median <br>Analyst:
Enriched sample ontology terms on this co-expression cluster<b>Summary:</b>To summarize promoter activities (expression profile of a TSS region) across ~1000 samples, we performed enrichment analysis based on FANTOM5 Sample Ontology (FF ontology). The question here is “in which type of samples the promoter is more active”. To answer this question, we compared expressions (TPMs) in the samples associated with a sample ontology term and the rest of the samples by using the Mann-Whitney rank sum test. To summarize ontologies enriched in this co-expression cluster, we ran the same analysis on an averaged expression profile of all promoters that make up. <b>Analyst:</b> Hideya Kawaji <br><br>links to source dataset<br><br><br>uberon_data<br><br>
Ontology term | p-value | n |
---|---|---|
neurectoderm | 8.13e-18 | 64 |
neural plate | 8.13e-18 | 64 |
presumptive neural plate | 8.13e-18 | 64 |
regional part of nervous system | 3.67e-16 | 54 |
neural tube | 6.20e-16 | 52 |
neural rod | 6.20e-16 | 52 |
future spinal cord | 6.20e-16 | 52 |
neural keel | 6.20e-16 | 52 |
ecto-epithelium | 1.69e-15 | 73 |
pre-chordal neural plate | 2.49e-14 | 49 |
brain | 3.14e-14 | 47 |
future brain | 3.14e-14 | 47 |
regional part of brain | 2.43e-13 | 46 |
occipital lobe | 1.74e-11 | 10 |
visual cortex | 1.74e-11 | 10 |
neocortex | 1.74e-11 | 10 |
gray matter | 2.06e-11 | 34 |
ectoderm-derived structure | 2.87e-11 | 95 |
ectoderm | 2.87e-11 | 95 |
presumptive ectoderm | 2.87e-11 | 95 |
anterior neural tube | 3.98e-11 | 40 |
central nervous system | 8.84e-11 | 73 |
regional part of forebrain | 2.15e-10 | 39 |
forebrain | 2.15e-10 | 39 |
future forebrain | 2.15e-10 | 39 |
nervous system | 3.55e-10 | 75 |
structure with developmental contribution from neural crest | 3.57e-10 | 92 |
brain grey matter | 1.06e-09 | 29 |
regional part of telencephalon | 1.06e-09 | 29 |
telencephalon | 1.06e-09 | 29 |
regional part of cerebral cortex | 4.74e-08 | 17 |
cerebral cortex | 4.38e-07 | 21 |
cerebral hemisphere | 4.38e-07 | 21 |
pallium | 4.38e-07 | 21 |
TFBS overrepresentation<b>Summary:</b>The values shown are the p-values for overrepresentation of the motif in this coexpression cluster. So a small p-value means a strong overrepresentation. <b>Analyst:</b> Michiel de Hoon <br><br>link to source data <br> Novel motifs <br>data <br><br> Jaspar motifs <br>data
Novel motifs
JASPAR motifs
Motifs | -log10(p-value) |
---|---|
MA0003.1 | 5.78107 |
MA0004.1 | 0.303605 |
MA0006.1 | 0.496735 |
MA0007.1 | 0.290695 |
MA0009.1 | 0.709264 |
MA0014.1 | 0.109847 |
MA0017.1 | 0.186015 |
MA0019.1 | 0.535691 |
MA0024.1 | 0.667197 |
MA0025.1 | 2.15573 |
MA0027.1 | 2.34178 |
MA0028.1 | 0.173587 |
MA0029.1 | 0.64639 |
MA0030.1 | 0.65267 |
MA0031.1 | 0.618697 |
MA0038.1 | 0.432665 |
MA0040.1 | 0.721328 |
MA0041.1 | 0.239557 |
MA0042.1 | 0.228771 |
MA0043.1 | 0.802848 |
MA0046.1 | 0.743934 |
MA0048.1 | 0.168666 |
MA0050.1 | 0.337476 |
MA0051.1 | 0.440863 |
MA0052.1 | 0.729105 |
MA0055.1 | 0.226387 |
MA0056.1 | 0 |
MA0057.1 | 0.151898 |
MA0058.1 | 0.223242 |
MA0059.1 | 0.233271 |
MA0060.1 | 0.108526 |
MA0061.1 | 1.89666 |
MA0063.1 | 0 |
MA0066.1 | 0.422624 |
MA0067.1 | 1.04514 |
MA0068.1 | 0.157638 |
MA0069.1 | 0.729433 |
MA0070.1 | 0.720077 |
MA0071.1 | 0.336739 |
MA0072.1 | 0.711905 |
MA0073.1 | 1.92927 |
MA0074.1 | 1.01196 |
MA0076.1 | 0.200996 |
MA0077.1 | 0.691048 |
MA0078.1 | 0.471303 |
MA0081.1 | 0.252371 |
MA0083.1 | 0.802078 |
MA0084.1 | 1.3693 |
MA0087.1 | 0.760279 |
MA0088.1 | 0.459114 |
MA0089.1 | 0 |
MA0090.1 | 0.753315 |
MA0091.1 | 0.315003 |
MA0092.1 | 0.274547 |
MA0093.1 | 0.179936 |
MA0095.1 | 0 |
MA0098.1 | 0 |
MA0100.1 | 0.379666 |
MA0101.1 | 0.675688 |
MA0103.1 | 0.566591 |
MA0105.1 | 2.34739 |
MA0106.1 | 0.478503 |
MA0107.1 | 1.66802 |
MA0108.2 | 1.37095 |
MA0109.1 | 0 |
MA0111.1 | 0.286331 |
MA0113.1 | 0.452439 |
MA0114.1 | 0.127366 |
MA0115.1 | 0.805567 |
MA0116.1 | 0.165534 |
MA0117.1 | 0.774259 |
MA0119.1 | 0.676816 |
MA0122.1 | 0.793507 |
MA0124.1 | 0.992825 |
MA0125.1 | 0.920215 |
MA0130.1 | 0 |
MA0131.1 | 0.531427 |
MA0132.1 | 0 |
MA0133.1 | 0 |
MA0135.1 | 0.838263 |
MA0136.1 | 0.408073 |
MA0139.1 | 0.61859 |
MA0140.1 | 0.379562 |
MA0141.1 | 0.210047 |
MA0142.1 | 0.604892 |
MA0143.1 | 0.467531 |
MA0144.1 | 0.807435 |
MA0145.1 | 0.264944 |
MA0146.1 | 0.910217 |
MA0147.1 | 0.428193 |
MA0148.1 | 0.317692 |
MA0149.1 | 0.245177 |
MA0062.2 | 0.235333 |
MA0035.2 | 0.383789 |
MA0039.2 | 0.262354 |
MA0138.2 | 0.523978 |
MA0002.2 | 0.627335 |
MA0137.2 | 0.207733 |
MA0104.2 | 0.326825 |
MA0047.2 | 0.431964 |
MA0112.2 | 1.15536 |
MA0065.2 | 0.265926 |
MA0150.1 | 0.290598 |
MA0151.1 | 0 |
MA0152.1 | 0.432062 |
MA0153.1 | 0.854464 |
MA0154.1 | 0.16541 |
MA0155.1 | 0.127763 |
MA0156.1 | 0.200311 |
MA0157.1 | 0.574484 |
MA0158.1 | 0 |
MA0159.1 | 0.145521 |
MA0160.1 | 0.320315 |
MA0161.1 | 0 |
MA0162.1 | 0.748622 |
MA0163.1 | 0.692813 |
MA0164.1 | 0.408402 |
MA0080.2 | 0.190316 |
MA0018.2 | 0.417217 |
MA0099.2 | 0.518072 |
MA0079.2 | 0.275611 |
MA0102.2 | 1.42135 |
MA0258.1 | 0.118033 |
MA0259.1 | 0.130633 |
MA0442.1 | 0 |