UBERON:0002107: Difference between revisions
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|has_quality= | |has_quality= | ||
|id=UBERON:0002107 | |id=UBERON:0002107 | ||
|is_a=UBERON:0002365;;UBERON:0004119;;UBERON:0005172;;UBERON:0006925 | |is_a=UBERON:0002365 ;;UBERON:0004119 ;;UBERON:0005172 ;;UBERON:0006925 | ||
|is_obsolete= | |is_obsolete= | ||
|located_in= | |located_in= | ||
|name=liver | |name=liver | ||
|namespace= | |namespace=FANTOM | ||
|obo_creation_date= | |obo_creation_date= | ||
|part_of=UBERON:0000916;;UBERON:0000949;;UBERON:0001007;;UBERON:0002330;;UBERON:0002423 | |part_of=UBERON:0000916;;UBERON:0000949;;UBERON:0001007;;UBERON:0002330;;UBERON:0002423 |
Latest revision as of 17:26, 12 September 2014
Name: | liver | ||
---|---|---|---|
Namespace: | FANTOM | ||
Definition: | "An exocrine gland which secretes bile and functions in metabolism of protein and carbohydrate and fat, synthesizes substances involved in the clotting of the blood, synthesizes vitamin A, detoxifies poisonous substances, stores glycogen, and breaks down worn-out erythrocytes[GO]." [BTO:0000759, Wikipedia:Liver] | ||
Xrefs: |
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Synonyms: | "jecur, iecer" RELATED LATIN [Wikipedia:Liver] | ||
Comments: | AO notes: Only ZFA considers this part_of immune system - we weaken this to an overlaps relation, as in general it's only a subset of cells that have clear immune function. Taxon notes: WP: The liver is found in all vertebrates, and is typically the largest visceral organ. Its form varies considerably in different species, and is largely determined by the shape and arrangement of the surrounding organs. Nonetheless, in most species it is divided into right and left lobes; exceptions to this general rule include snakes, where the shape of the body necessitates a simple cigar-like form. The internal structure of the liver is broadly similar in all vertebrates.[7] An organ sometimes referred to as a liver is found associated with the digestive tract of the primitive chordate Amphioxus. However, this is an enzyme secreting gland, not a metabolic organ, and it is unclear how truly homologous it is to the vertebrate liver. | ||
Alt_id: | UBERON:FMA_7197-MA_0000358-MIAA_0000097-XAO_0000133-ZFA_0000123 | ||
Subset: |
major_organ organ_slim uberon_slim vertebrate_core |
Ontology association<br>Each term has an is_a parent in the Uberon Ontology, which has a linkage to an another entity and FANTOM5 samples.Libraries were grouped into mutually exclusive facets according to the FANTOM5 sample ontology mapping to UBERON ontologies.<br><br>link to ontology dataset<br>data
Parents
is_a: | UBERON:0002365(exocrine gland),UBERON:0004119(endoderm-derived structure),UBERON:0005172(abdomen element),UBERON:0006925(digestive gland) |
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develops_from: | UBERON:0003894(liver primordium),UBERON:0004161(septum transversum),UBERON:0008836(liver bud) |
part_of: | UBERON:0000916(abdomen),UBERON:0000949(endocrine system),UBERON:0001007(digestive system),UBERON:0002330(exocrine system),UBERON:0002423(hepatobiliary system) |
Children
derives from: | FF:0010018 (human liver - adult sample),FF:0010086 (human liver - fetal sample),FF:0011320 (mouse liver- embryo E12 sample),FF:0011328 (mouse liver- embryo E13 sample),FF:0011340 (mouse liver- embryo E14 sample),FF:0011349 (mouse liver- embryo E15 sample),FF:0011361 (mouse liver- embryo E16 sample),FF:0011369 (mouse liver- embryo E17 sample),FF:0011376 (mouse liver- embryo E18 sample),FF:0011379 (mouse liver- adult pregnant day01 sample),FF:0011395 (mouse liver- neonate N00 sample),FF:0011403 (mouse liver- neonate N06 sample),FF:0011409 (mouse liver- neonate N07 sample),FF:0011416 (mouse liver- neonate N10 sample),FF:0011429 (mouse liver- neonate N20 sample),FF:0011484 (mouse liver- neonate N03 sample),FF:0011485 (mouse liver- neonate N25 sample),FF:0011486 (mouse liver- neonate N30 sample),FF:0100224 (liver cell line sample) |
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part of: | CL:0000182 (hepatocyte),CL:0000632 (hepatic stellate cell),UBERON:0001280 (liver parenchyma),UBERON:0001281 (hepatic sinusoid),CL:0002195 (hepatic stem cell),CL:0002571 (hepatic mesenchymal stem cell),UBERON:0003704 (intrahepatic bile duct),UBERON:0006877 (vasculature of liver),UBERON:0015796 (liver blood vessel) |
Ontology Tree: Loaded from BioPortal
Ontorolgy tree(Small window open)
FF samples<br>It includes FANTOM5 samples that overlay the Uberon ontology
Human (Homo sapiens)
- 10018-101C9 (liver, adult, pool1)
- 10086-102B5 (liver, fetal, pool1)
- 10089-102B8
- 10484-107A7 (hepatoma cell line:Li-7)
- 10536-107G5 (cholangiocellular carcinoma cell line:HuH-28)
- 10629-108H8
- 10630-108H9
- 10632-108I2
- 10633-108I3 (hepatoblastoma cell line:HuH-6)
- 10706-109H4 (pleomorphic hepatocellular carcinoma cell line:SNU-387)
... further results Mouse (Mus musculus)
- 10018-101C9 (liver, adult, pool1)
- 10086-102B5 (liver, fetal, pool1)
- 10089-102B8
- 10484-107A7 (hepatoma cell line:Li-7)
- 10536-107G5 (cholangiocellular carcinoma cell line:HuH-28)
- 10629-108H8
- 10630-108H9
- 10632-108I2
- 10633-108I3 (hepatoblastoma cell line:HuH-6)
- 10706-109H4 (pleomorphic hepatocellular carcinoma cell line:SNU-387)
Enrichment analysis: top 100 FFCP enriched with this ontology term TOP 100 FANTOM5 Cage Peaks enriched with UBERON:0002107 (liver), sorted by p-values <br>Analyst: Hideya Kawaji<br><br>link to source dataset <br>human : data <br>mouse : data
P-value | FFCP | Short description |
---|---|---|
3.93e-83 | FFCP PHASE2:Hg19::chr12:100867777..100867788,+#_d23f8b9a7a7fa496066ab77ee2f7eaa2 | p5@NR1H4 |
3.93e-83 | FFCP PHASE1:Hg19::chr12:100867777..100867788,+#_d23f8b9a7a7fa496066ab77ee2f7eaa2 | p5@NR1H4 |
1.46e-82 | FFCP PHASE1:Hg19::chr8:144417558..144417572,-#_820e70d67b222ca2e5c6c419e4e0f4cc | p7@TOP1MT |
1.46e-82 | FFCP PHASE1:Hg19::chr2:21233797..21233804,-#_820e70d67b222ca2e5c6c419e4e0f4cc | p58@APOB |
1.46e-82 | FFCP PHASE2:Hg19::chr2:21233797..21233804,-#_820e70d67b222ca2e5c6c419e4e0f4cc | p58@APOB |
1.46e-82 | FFCP PHASE2:Hg19::chr8:144417558..144417572,-#_820e70d67b222ca2e5c6c419e4e0f4cc | p7@TOP1MT |
5.75e-76 | FFCP PHASE2:Hg19::chrX:153769426..153769436,+#_8b260d0a09e3f2a5a56a640a1c773a67 | p18@IKBKG |
5.75e-76 | FFCP PHASE1:Hg19::chrX:153769426..153769436,+#_8b260d0a09e3f2a5a56a640a1c773a67 | p18@IKBKG |
9.69e-76 | FFCP PHASE1:Hg19::chr10:7745167..7745178,+#_fbadd152fd9675cef01f72d0c072597a | p3@ITIH2 |
9.69e-76 | FFCP PHASE2:Hg19::chr10:7745167..7745178,+#_fbadd152fd9675cef01f72d0c072597a | p3@ITIH2 |
1.94e-75 | FFCP PHASE2:Hg19::chr2:97216132..97216143,+#_500b02183908449299436f1b80831ed4 | p@chr2:97216132..97216143, + |
1.94e-75 | FFCP PHASE1:Hg19::chr2:97216132..97216143,+#_500b02183908449299436f1b80831ed4 | p@chr2:97216132..97216143, + |
1.74e-73 | FFCP PHASE1:Hg19::chr20:10349456..10349475,-#_f9f0d93bb84ba861f1b3d3787127c201 | p1@ENST00000421143 |
1.74e-73 | FFCP PHASE2:Hg19::chr2:21239379..21239390,-#_f9f0d93bb84ba861f1b3d3787127c201 | p@chr2:21239379..21239390, - |
1.74e-73 | FFCP PHASE1:Hg19::chr10:82049381..82049384,-#_f9f0d93bb84ba861f1b3d3787127c201 | p9@MAT1A |
1.74e-73 | FFCP PHASE2:Hg19::chr2:21258509..21258518,-#_f9f0d93bb84ba861f1b3d3787127c201 | p@chr2:21258509..21258518, - |
1.74e-73 | FFCP PHASE2:Hg19::chr2:21228233..21228242,-#_f9f0d93bb84ba861f1b3d3787127c201 | p56@APOB |
1.74e-73 | FFCP PHASE1:Hg19::chr2:21258509..21258518,-#_f9f0d93bb84ba861f1b3d3787127c201 | p@chr2:21258509..21258518, - |
1.74e-73 | FFCP PHASE1:Hg19::chr2:21228233..21228242,-#_f9f0d93bb84ba861f1b3d3787127c201 | p56@APOB |
1.74e-73 | FFCP PHASE2:Hg19::chr20:10349456..10349475,-#_f9f0d93bb84ba861f1b3d3787127c201 | p1@ENST00000421143 |
1.74e-73 | FFCP PHASE2:Hg19::chr20:22566089..22566097,-#_f9f0d93bb84ba861f1b3d3787127c201 | p6@FOXA2 |
1.74e-73 | FFCP PHASE1:Hg19::chr2:21239379..21239390,-#_f9f0d93bb84ba861f1b3d3787127c201 | p@chr2:21239379..21239390, - |
1.74e-73 | FFCP PHASE2:Hg19::chr10:82049381..82049384,-#_f9f0d93bb84ba861f1b3d3787127c201 | p9@MAT1A |
1.74e-73 | FFCP PHASE1:Hg19::chr20:22566089..22566097,-#_f9f0d93bb84ba861f1b3d3787127c201 | p6@FOXA2 |
2.11e-73 | FFCP PHASE2:Hg19::chr1:230846000..230846009,-#_5cdf544678ddc8e12f47e026ad59a679 | p@chr1:230846000..230846009, - |
2.11e-73 | FFCP PHASE1:Hg19::chr14:94844853..94844862,-#_5cdf544678ddc8e12f47e026ad59a679 | p35@SERPINA1 |
2.11e-73 | FFCP PHASE2:Hg19::chr14:94844853..94844862,-#_5cdf544678ddc8e12f47e026ad59a679 | p35@SERPINA1 |
2.11e-73 | FFCP PHASE1:Hg19::chr1:230846000..230846009,-#_5cdf544678ddc8e12f47e026ad59a679 | p@chr1:230846000..230846009, - |
1.22e-72 | FFCP PHASE2:Mm9::chr5:90897694..90897705,+#_565549a1af54e13e94a0e201aea4352b | p@chr5:90897694..90897705, + |
1.22e-72 | FFCP PHASE1:Mm9::chr5:90897694..90897705,+#_565549a1af54e13e94a0e201aea4352b | p@chr5:90897694..90897705, + |
1.97e-72 | FFCP PHASE2:Hg19::chr2:21256369..21256378,-#_4333af4ef5bec69e8628066b0a707a19 | p@chr2:21256369..21256378, - |
1.97e-72 | FFCP PHASE1:Hg19::chr2:21232865..21232870,-#_4333af4ef5bec69e8628066b0a707a19 | p10@BC172787 |
1.97e-72 | FFCP PHASE1:Hg19::chr2:21256369..21256378,-#_4333af4ef5bec69e8628066b0a707a19 | p@chr2:21256369..21256378, - |
1.97e-72 | FFCP PHASE1:Hg19::chr10:7763609..7763619,+#_4333af4ef5bec69e8628066b0a707a19 | p@chr10:7763609..7763619, + |
1.97e-72 | FFCP PHASE1:Hg19::chr2:44066386..44066398,-#_4333af4ef5bec69e8628066b0a707a19 | p6@ABCG5 |
1.97e-72 | FFCP PHASE2:Hg19::chr10:7763609..7763619,+#_4333af4ef5bec69e8628066b0a707a19 | p@chr10:7763609..7763619, + |
1.97e-72 | FFCP PHASE1:Hg19::chr12:57828432..57828442,+#_4333af4ef5bec69e8628066b0a707a19 | p7@INHBC |
1.97e-72 | FFCP PHASE2:Hg19::chr2:21230675..21230682,-#_4333af4ef5bec69e8628066b0a707a19 | p51@APOB |
1.97e-72 | FFCP PHASE1:Hg19::chr2:21234502..21234510,-#_4333af4ef5bec69e8628066b0a707a19 | p43@APOB |
1.97e-72 | FFCP PHASE2:Hg19::chr2:21232865..21232870,-#_4333af4ef5bec69e8628066b0a707a19 | p10@BC172787 |
1.97e-72 | FFCP PHASE2:Hg19::chr2:21234502..21234510,-#_4333af4ef5bec69e8628066b0a707a19 | p43@APOB |
1.97e-72 | FFCP PHASE2:Hg19::chr2:20793103..20793113,-#_4333af4ef5bec69e8628066b0a707a19 | p@chr2:20793103..20793113, - |
1.97e-72 | FFCP PHASE2:Hg19::chr17:7082861..7082882,-#_4333af4ef5bec69e8628066b0a707a19 | p9@ASGR1 |
1.97e-72 | FFCP PHASE2:Hg19::chr12:57828432..57828442,+#_4333af4ef5bec69e8628066b0a707a19 | p7@INHBC |
1.97e-72 | FFCP PHASE1:Hg19::chr2:20793103..20793113,-#_4333af4ef5bec69e8628066b0a707a19 | p@chr2:20793103..20793113, - |
1.97e-72 | FFCP PHASE1:Hg19::chr17:7082861..7082882,-#_4333af4ef5bec69e8628066b0a707a19 | p9@ASGR1 |
1.97e-72 | FFCP PHASE1:Hg19::chr2:21231676..21231681,-#_4333af4ef5bec69e8628066b0a707a19 | p75@APOB |
1.97e-72 | FFCP PHASE1:Hg19::chr2:21230675..21230682,-#_4333af4ef5bec69e8628066b0a707a19 | p51@APOB |
1.97e-72 | FFCP PHASE2:Hg19::chr2:44066386..44066398,-#_4333af4ef5bec69e8628066b0a707a19 | p6@ABCG5 |
1.97e-72 | FFCP PHASE2:Hg19::chr2:21231676..21231681,-#_4333af4ef5bec69e8628066b0a707a19 | p75@APOB |
2.2e-72 | FFCP PHASE1:Mm9::chr19:25169885..25169900,+#_c2d617a45ba2d7071a2463b464b49e57 | p@chr19:25169885..25169900, + |
2.2e-72 | FFCP PHASE2:Mm9::chr19:25169885..25169900,+#_c2d617a45ba2d7071a2463b464b49e57 | p@chr19:25169885..25169900, + |
5.51e-71 | FFCP PHASE1:Mm9::chr7:121912281..121912295,+#_de7762314134dc18c1a4b343c879bc20 | p6@Insc |
5.51e-71 | FFCP PHASE2:Mm9::chr7:121912281..121912295,+#_de7762314134dc18c1a4b343c879bc20 | p6@Insc |
1.05e-70 | FFCP PHASE2:Hg19::chr12:100867695..100867706,+#_94921d8a33827bc3b39a7dc4bc6132da | p6@NR1H4 |
1.05e-70 | FFCP PHASE1:Hg19::chr12:100867695..100867706,+#_94921d8a33827bc3b39a7dc4bc6132da | p6@NR1H4 |
1.7e-70 | FFCP PHASE1:Mm9::chr8:131012371..131012382,-#_6f8686f7a6eab1e2b12e797c6370ac00 | p2@uc009nzu.1 |
1.7e-70 | FFCP PHASE2:Mm9::chr8:131012371..131012382,-#_6f8686f7a6eab1e2b12e797c6370ac00 | p2@uc009nzu.1 |
8.65e-70 | FFCP PHASE1:Hg19::chr17:7082560..7082572,-#_b58309d53618b2c18e19c2f7d1e28eed | p4@ASGR1 |
8.65e-70 | FFCP PHASE2:Hg19::chr17:7082560..7082572,-#_b58309d53618b2c18e19c2f7d1e28eed | p4@ASGR1 |
1.02e-69 | FFCP PHASE2:Hg19::chr10:72083665..72083701,-#_3d720e4866b53bded86b24a6851bdfef | p2@LRRC20 |
1.02e-69 | FFCP PHASE1:Hg19::chr10:72083665..72083701,-#_3d720e4866b53bded86b24a6851bdfef | p2@LRRC20 |
1.64e-69 | FFCP PHASE2:Hg19::chr1:11107289..11107304,-#_b8329beff6e9adf606f6fe8855e32d53 | p1@MASP2 |
1.64e-69 | FFCP PHASE2:Hg19::chr9:116838918..116838930,-#_b8329beff6e9adf606f6fe8855e32d53 | p@chr9:116838918..116838930, - |
1.64e-69 | FFCP PHASE1:Hg19::chr9:116838918..116838930,-#_b8329beff6e9adf606f6fe8855e32d53 | p@chr9:116838918..116838930, - |
1.64e-69 | FFCP PHASE1:Hg19::chr1:11107289..11107304,-#_b8329beff6e9adf606f6fe8855e32d53 | p1@MASP2 |
2.08e-69 | FFCP PHASE1:Hg19::chr3:197300199..197300219,-#_82bc304d773def4212e36234058ef628 | p2@BDH1 |
2.08e-69 | FFCP PHASE2:Hg19::chr3:197300199..197300219,-#_82bc304d773def4212e36234058ef628 | p2@BDH1 |
2.25e-69 | FFCP PHASE2:Hg19::chr4:155528001..155528060,-#_9d96dfd9e226208cbb11bb2ff74842ed | p@chr4:155528001..155528060, - |
2.25e-69 | FFCP PHASE2:Hg19::chr19:45430057..45430062,+#_9d96dfd9e226208cbb11bb2ff74842ed | p1@APOC1P1 |
2.25e-69 | FFCP PHASE1:Hg19::chr9:116838988..116838999,-#_9d96dfd9e226208cbb11bb2ff74842ed | p@chr9:116838988..116838999, - |
2.25e-69 | FFCP PHASE2:Hg19::chr9:116838988..116838999,-#_9d96dfd9e226208cbb11bb2ff74842ed | p@chr9:116838988..116838999, - |
2.25e-69 | FFCP PHASE1:Hg19::chr4:155528001..155528060,-#_9d96dfd9e226208cbb11bb2ff74842ed | p@chr4:155528001..155528060, - |
2.25e-69 | FFCP PHASE1:Hg19::chr19:45430057..45430062,+#_9d96dfd9e226208cbb11bb2ff74842ed | p1@APOC1P1 |
2.64e-69 | FFCP PHASE2:Hg19::chr17:7017634..7017649,-#_8c2be9342882878c94e62c405896e73f | p7@ASGR2 |
2.64e-69 | FFCP PHASE1:Hg19::chr17:7017634..7017649,-#_8c2be9342882878c94e62c405896e73f | p7@ASGR2 |
2.64e-69 | FFCP PHASE1:Hg19::chr11:116662593..116662620,-#_8c2be9342882878c94e62c405896e73f | p1@APOA5 |
2.64e-69 | FFCP PHASE2:Hg19::chr11:116662593..116662620,-#_8c2be9342882878c94e62c405896e73f | p1@APOA5 |
1.28e-68 | FFCP PHASE2:Mm9::chr13:94407586..94407604,-#_b978123e099b6fbd3786a886d768a653 | p5@Bhmt |
1.28e-68 | FFCP PHASE1:Mm9::chr13:94407586..94407604,-#_b978123e099b6fbd3786a886d768a653 | p5@Bhmt |
2.72e-68 | FFCP PHASE2:Mm9::chr1:162917234..162917248,+#_91bb96e93653bb7a10680f38a36f2fb3 | p@chr1:162917234..162917248, + |
2.72e-68 | FFCP PHASE1:Mm9::chr1:162917234..162917248,+#_91bb96e93653bb7a10680f38a36f2fb3 | p@chr1:162917234..162917248, + |
3.5e-68 | FFCP PHASE2:Mm9::chr9:110892216..110892232,-#_62d7fd9a88d2e0adb17ae4e355b468b0 | p1@Rtp3 |
3.5e-68 | FFCP PHASE1:Mm9::chr9:110892216..110892232,-#_62d7fd9a88d2e0adb17ae4e355b468b0 | p1@Rtp3 |
2.47e-67 | FFCP PHASE2:Mm9::chr9:110892239..110892252,-#_6ac68a5ff2955cba481f45fd8664c6db | p2@Rtp3 |
2.47e-67 | FFCP PHASE2:Mm9::chr7:112744083..112744109,-#_6ac68a5ff2955cba481f45fd8664c6db | p@chr7:112744083..112744109, - |
2.47e-67 | FFCP PHASE1:Mm9::chr7:112744083..112744109,-#_6ac68a5ff2955cba481f45fd8664c6db | p@chr7:112744083..112744109, - |
2.47e-67 | FFCP PHASE1:Mm9::chr9:110892239..110892252,-#_6ac68a5ff2955cba481f45fd8664c6db | p2@Rtp3 |
6.55e-67 | FFCP PHASE2:Mm9::chr13:23928766..23928779,+#_4b3a9f9dbad3c4262694112a89ffce45 | p@chr13:23928766..23928779, + |
6.55e-67 | FFCP PHASE1:Mm9::chr13:23928766..23928779,+#_4b3a9f9dbad3c4262694112a89ffce45 | p@chr13:23928766..23928779, + |
7.85e-67 | FFCP PHASE2:Mm9::chr7:28237436..28237488,+#_81dc07a7d10185efce398654f09850e4 | p3@Blvrb |
7.85e-67 | FFCP PHASE1:Mm9::chr7:28237436..28237488,+#_81dc07a7d10185efce398654f09850e4 | p3@Blvrb |
1.58e-66 | FFCP PHASE2:Mm9::chr12:105004018..105004046,-#_89ca54c41602cbe2f12290a07b4cbb2f | p@chr12:105004018..105004046, - |
1.58e-66 | FFCP PHASE1:Mm9::chr12:105004018..105004046,-#_89ca54c41602cbe2f12290a07b4cbb2f | p@chr12:105004018..105004046, - |
1.58e-66 | FFCP PHASE1:Mm9::chr2:10041210..10041222,-#_89ca54c41602cbe2f12290a07b4cbb2f | p@chr2:10041210..10041222, - |
1.58e-66 | FFCP PHASE1:Mm9::chr16:22894900..22894910,+#_89ca54c41602cbe2f12290a07b4cbb2f | p@chr16:22894900..22894910, + |
1.58e-66 | FFCP PHASE2:Mm9::chr2:10041210..10041222,-#_89ca54c41602cbe2f12290a07b4cbb2f | p@chr2:10041210..10041222, - |
1.58e-66 | FFCP PHASE2:Mm9::chr6:128436166..128436185,-#_89ca54c41602cbe2f12290a07b4cbb2f | p@chr6:128436166..128436185, - |
1.58e-66 | FFCP PHASE1:Mm9::chr16:22898981..22898988,-#_89ca54c41602cbe2f12290a07b4cbb2f | p@chr16:22898981..22898988, - |
1.58e-66 | FFCP PHASE2:Mm9::chr16:22898981..22898988,-#_89ca54c41602cbe2f12290a07b4cbb2f | p@chr16:22898981..22898988, - |
Property "Property value" (as page type) with input value "UBPROP:0000001 "Organ which secretes bile and participates in formation of certain blood proteins.[AAO]" xsd:string" contains invalid characters or is incomplete and therefore can cause unexpected results during a query or annotation process., Property "Property value" (as page type) with input value "UBPROP:0000002 "relationship type change: differentiates_from endoderm (AAO:0000139) CHANGED TO: develops_from endoderm (UBERON:0000925)[AAO]" xsd:string" contains invalid characters or is incomplete and therefore can cause unexpected results during a query or annotation process.