Novel motif:124

name:	motif124_AATNCANCACT

Association to promoter expression in human samples<b>Summary:</b>Significance of the correlation with CAGE expression, human <br><b>Analyst:</b> Michiel de Hoon<br><br>link to source dataset <br>data

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Association to promoter expression in mouse samples <b>Summary:</b>Significance of the correlation with CAGE expression, mouse <br><b>Analyst:</b> Michiel de Hoon<br><br>link to source dataset <br>data

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GREAT analysis results for human <b>Summary:</b>Genomic Enrichment of Annotations Tool (GREAT, Nat Biotechnol. 2010 May;28(5):495-501) is used to identify, both in human and in mouse, the gene ontology terms of biological processes enriched given the predicted TFBSs, and evaluated the overlap in the top-500 gene ontology terms between human and mouse. For each novel motif, the P value for the overlap was then evaluated by calculating its relative rank with respect to this background distribution.<br>Analyst: Michiel de Hoon<br><br>link to source dataset <br>data

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GO ID	GO Term	p-value
GO:0034332	adherens junction organization	4.676747e-15
GO:0050896	response to stimulus	8.128399e-15
GO:0048583	regulation of response to stimulus	1.587519e-13
GO:0070584	mitochondrion morphogenesis	3.253570e-13
GO:0006955	immune response	5.038678e-13
GO:0023052	signaling	5.292504e-13
GO:0002376	immune system process	6.718726e-13
GO:0007165	signal transduction	6.756497e-13
GO:0007154	cell communication	7.040683e-13
GO:0051716	cellular response to stimulus	2.768604e-12
GO:0065008	regulation of biological quality	1.652654e-11
GO:0070972	protein localization in endoplasmic reticulum	3.910387e-11
GO:0045216	cell-cell junction organization	4.273008e-11
GO:0007166	cell surface receptor linked signaling pathway	5.157190e-11
GO:0032501	multicellular organismal process	2.442033e-10
GO:0034329	cell junction assembly	2.747252e-10
GO:0006626	protein targeting to mitochondrion	1.149764e-9
GO:0071636	positive regulation of transforming growth factor beta production	1.573204e-9
GO:0033036	macromolecule localization	1.786731e-9
GO:0034330	cell junction organization	2.189839e-9
GO:0007186	G-protein coupled receptor protein signaling pathway	3.327249e-9
GO:0007275	multicellular organismal development	3.732867e-9
GO:0006621	protein retention in ER lumen	6.870480e-9
GO:0070585	protein localization in mitochondrion	7.552075e-9
GO:0008104	protein localization	7.776208e-9
GO:0072655	establishment of protein localization in mitochondrion	7.887131e-9
GO:0048513	organ development	8.278199e-9
GO:0048518	positive regulation of biological process	9.035453e-9
GO:0021572	rhombomere 6 development	1.142648e-8
GO:0032502	developmental process	1.260300e-8
GO:0051336	regulation of hydrolase activity	1.464655e-8
GO:0045321	leukocyte activation	1.761741e-8
GO:0001798	positive regulation of type IIa hypersensitivity	2.017845e-8
GO:0006952	defense response	2.242763e-8
GO:0042403	thyroid hormone metabolic process	2.741257e-8
GO:0070050	neuron homeostasis	3.163111e-8
GO:0006612	protein targeting to membrane	3.296047e-8
GO:0002706	regulation of lymphocyte mediated immunity	3.716477e-8
GO:0033365	protein localization to organelle	4.461418e-8
GO:0042110	T cell activation	4.758896e-8
GO:0009913	epidermal cell differentiation	6.269384e-8
GO:0071634	regulation of transforming growth factor beta production	6.346441e-8
GO:0048856	anatomical structure development	6.618919e-8
GO:0001819	positive regulation of cytokine production	7.094939e-8
GO:0045040	protein import into mitochondrial outer membrane	7.383440e-8
GO:0042445	hormone metabolic process	7.557807e-8
GO:0045766	positive regulation of angiogenesis	7.926618e-8
GO:0035621	ER to Golgi ceramide transport	7.982914e-8
GO:0032101	regulation of response to external stimulus	1.020525e-7
GO:0051270	regulation of cellular component movement	1.057842e-7
GO:0048731	system development	1.059735e-7
GO:0001952	regulation of cell-matrix adhesion	1.066097e-7
GO:0002682	regulation of immune system process	1.197280e-7
GO:0008588	release of cytoplasmic sequestered NF-kappaB	1.264918e-7
GO:0072594	establishment of protein localization to organelle	1.279991e-7
GO:0042221	response to chemical stimulus	1.564899e-7
GO:0048630	skeletal muscle tissue growth	1.626688e-7
GO:0042592	homeostatic process	1.839806e-7
GO:0045765	regulation of angiogenesis	1.894823e-7
GO:0006605	protein targeting	2.113010e-7
GO:0002885	positive regulation of hypersensitivity	2.635099e-7
GO:0030216	keratinocyte differentiation	3.369833e-7
GO:0051179	localization	3.480711e-7
GO:0050776	regulation of immune response	3.523247e-7
GO:0040012	regulation of locomotion	3.681285e-7
GO:0007005	mitochondrion organization	3.862986e-7
GO:0010817	regulation of hormone levels	3.867747e-7
GO:0006590	thyroid hormone generation	3.966899e-7
GO:0031641	regulation of myelination	4.038871e-7
GO:0048522	positive regulation of cellular process	4.126423e-7
GO:2000145	regulation of cell motility	4.287227e-7
GO:0001970	positive regulation of activation of membrane attack complex	4.374365e-7
GO:0023051	regulation of signaling	4.475781e-7
GO:0046716	muscle cell homeostasis	4.481278e-7
GO:0045056	transcytosis	4.493270e-7
GO:2000146	negative regulation of cell motility	5.186238e-7
GO:0030336	negative regulation of cell migration	5.327142e-7
GO:0002703	regulation of leukocyte mediated immunity	5.888134e-7
GO:0051271	negative regulation of cellular component movement	6.322929e-7
GO:0090072	positive regulation of sodium ion transport via voltage-gated sodium channel activity	6.351379e-7
GO:0070613	regulation of protein processing	7.637720e-7
GO:0050766	positive regulation of phagocytosis	8.282006e-7
GO:0050793	regulation of developmental process	8.770449e-7
GO:0032879	regulation of localization	9.258649e-7
GO:0030334	regulation of cell migration	9.497591e-7
GO:0042993	positive regulation of transcription factor import into nucleus	1.028797e-6
GO:0009268	response to pH	1.132971e-6
GO:0007267	cell-cell signaling	1.159776e-6
GO:0051893	regulation of focal adhesion assembly	1.162106e-6
GO:0022407	regulation of cell-cell adhesion	1.278853e-6
GO:0030878	thyroid gland development	1.330169e-6
GO:0034619	cellular chaperone-mediated protein complex assembly	1.363757e-6
GO:0002709	regulation of T cell mediated immunity	1.419663e-6
GO:0046649	lymphocyte activation	1.487542e-6
GO:0010575	positive regulation vascular endothelial growth factor production	1.514649e-6
GO:0002883	regulation of hypersensitivity	1.558982e-6
GO:0051056	regulation of small GTPase mediated signal transduction	1.685351e-6
GO:0051131	chaperone-mediated protein complex assembly	1.803495e-6
GO:0032908	regulation of transforming growth factor beta1 production	1.880773e-6
GO:0048468	cell development	1.936457e-6
GO:0001654	eye development	1.960261e-6
GO:0072376	protein activation cascade	1.989450e-6
GO:0046578	regulation of Ras protein signal transduction	1.995367e-6
GO:0050789	regulation of biological process	2.074484e-6
GO:0040013	negative regulation of locomotion	2.089983e-6
GO:0015031	protein transport	2.321496e-6
GO:0048584	positive regulation of response to stimulus	2.703209e-6
GO:0032318	regulation of Ras GTPase activity	2.720702e-6
GO:0032914	positive regulation of transforming growth factor beta1 production	3.302736e-6
GO:0042178	xenobiotic catabolic process	3.544265e-6
GO:0048869	cellular developmental process	3.589194e-6
GO:0010954	positive regulation of protein processing	3.669333e-6
GO:0006184	GTP catabolic process	3.788947e-6
GO:0070727	cellular macromolecule localization	3.790913e-6
GO:0042098	T cell proliferation	3.797002e-6
GO:0034613	cellular protein localization	3.965754e-6
GO:0007156	homophilic cell adhesion	4.078180e-6
GO:0045834	positive regulation of lipid metabolic process	4.417627e-6
GO:0007423	sensory organ development	4.597697e-6
GO:0017038	protein import	4.882954e-6
GO:0030449	regulation of complement activation	5.076239e-6
GO:0048732	gland development	5.281701e-6
GO:0006958	complement activation, classical pathway	5.414634e-6
GO:0042462	eye photoreceptor cell development	5.996158e-6
GO:0050877	neurological system process	6.276163e-6
GO:0002866	positive regulation of acute inflammatory response to antigenic stimulus	6.364837e-6
GO:0033561	regulation of water loss via skin	6.455358e-6
GO:0046039	GTP metabolic process	7.007592e-6
GO:0051641	cellular localization	7.364990e-6
GO:0001953	negative regulation of cell-matrix adhesion	7.586606e-6
GO:0051494	negative regulation of cytoskeleton organization	7.659070e-6
GO:0015705	iodide transport	8.052872e-6
GO:0001775	cell activation	8.269655e-6
GO:0031347	regulation of defense response	9.100673e-6
GO:0065009	regulation of molecular function	9.441228e-6
GO:0045410	positive regulation of interleukin-6 biosynthetic process	9.753657e-6
GO:0071786	endoplasmic reticulum tubular network organization	1.004196e-5
GO:0002088	lens development in camera-type eye	1.016885e-5
GO:0009888	tissue development	1.023020e-5
GO:0009988	cell-cell recognition	1.042520e-5
GO:0051128	regulation of cellular component organization	1.063717e-5
GO:0030155	regulation of cell adhesion	1.109635e-5
GO:0050790	regulation of catalytic activity	1.117189e-5
GO:0042446	hormone biosynthetic process	1.121585e-5
GO:0080134	regulation of response to stress	1.123170e-5
GO:0045184	establishment of protein localization	1.146555e-5
GO:0072595	maintenance of protein localization to organelle	1.177771e-5
GO:0030154	cell differentiation	1.247619e-5
GO:0021571	rhombomere 5 development	1.258227e-5
GO:0050794	regulation of cellular process	1.316846e-5
GO:0070887	cellular response to chemical stimulus	1.379262e-5
GO:0018958	phenol-containing compound metabolic process	1.383282e-5
GO:0019933	cAMP-mediated signaling	1.396794e-5
GO:0008544	epidermis development	1.426051e-5
GO:0032938	negative regulation of translation in response to oxidative stress	1.437359e-5
GO:0030799	regulation of cyclic nucleotide metabolic process	1.441577e-5
GO:0045006	DNA deamination	1.563567e-5
GO:0007191	activation of adenylate cyclase activity by dopamine receptor signaling pathway	1.570841e-5
GO:0046651	lymphocyte proliferation	1.625330e-5
GO:0048294	negative regulation of isotype switching to IgE isotypes	1.682738e-5
GO:0042461	photoreceptor cell development	1.804551e-5
GO:0006810	transport	1.818091e-5
GO:0002456	T cell mediated immunity	1.853072e-5
GO:0044093	positive regulation of molecular function	1.917674e-5
GO:0015889	cobalamin transport	1.965591e-5
GO:0006935	chemotaxis	1.971834e-5
GO:0050764	regulation of phagocytosis	2.143411e-5
GO:0010646	regulation of cell communication	2.216559e-5
GO:0035270	endocrine system development	2.315554e-5
GO:0032320	positive regulation of Ras GTPase activity	2.383691e-5
GO:0002708	positive regulation of lymphocyte mediated immunity	2.481428e-5
GO:2000026	regulation of multicellular organismal development	2.516126e-5
GO:0051234	establishment of localization	2.528793e-5
GO:0032943	mononuclear cell proliferation	2.585807e-5
GO:0048521	negative regulation of behavior	2.599700e-5
GO:0046463	acylglycerol biosynthetic process	2.663209e-5
GO:0043010	camera-type eye development	2.742382e-5
GO:0006140	regulation of nucleotide metabolic process	2.773217e-5
GO:0032368	regulation of lipid transport	2.798266e-5
GO:0046755	non-lytic virus budding	2.845416e-5
GO:0060341	regulation of cellular localization	2.908157e-5
GO:0010765	positive regulation of sodium ion transport	2.948480e-5
GO:0006956	complement activation	2.955885e-5
GO:0035690	cellular response to drug	2.958764e-5
GO:0030217	T cell differentiation	3.021941e-5
GO:0090003	regulation of establishment of protein localization in plasma membrane	3.051608e-5
GO:0009653	anatomical structure morphogenesis	3.086053e-5
GO:0007190	activation of adenylate cyclase activity	3.169257e-5
GO:0050663	cytokine secretion	3.334812e-5
GO:0090273	regulation of somatostatin secretion	3.437419e-5
GO:0001817	regulation of cytokine production	3.488433e-5
GO:0065007	biological regulation	3.497084e-5
GO:0031394	positive regulation of prostaglandin biosynthetic process	3.515199e-5
GO:0071466	cellular response to xenobiotic stimulus	3.531843e-5
GO:0051239	regulation of multicellular organismal process	3.534403e-5
GO:0050808	synapse organization	3.774354e-5
GO:0070206	protein trimerization	3.822147e-5
GO:0002864	regulation of acute inflammatory response to antigenic stimulus	3.897223e-5
GO:0042537	benzene-containing compound metabolic process	3.909810e-5
GO:0006805	xenobiotic metabolic process	3.969776e-5
GO:0046504	glycerol ether biosynthetic process	3.991282e-5
GO:0044281	small molecule metabolic process	4.100101e-5
GO:0043154	negative regulation of caspase activity	4.114292e-5
GO:0019432	triglyceride biosynthetic process	4.148659e-5
GO:0007029	endoplasmic reticulum organization	4.326166e-5
GO:0032851	positive regulation of Rab GTPase activity	4.440055e-5
GO:0009966	regulation of signal transduction	4.510691e-5
GO:0019935	cyclic-nucleotide-mediated signaling	4.588019e-5
GO:0071622	regulation of granulocyte chemotaxis	4.609789e-5
GO:0042346	positive regulation of NF-kappaB import into nucleus	4.652028e-5
GO:0032916	positive regulation of transforming growth factor beta3 production	4.669377e-5
GO:0090201	negative regulation of release of cytochrome c from mitochondria	4.724647e-5
GO:0060249	anatomical structure homeostasis	4.842662e-5
GO:0007043	cell-cell junction assembly	4.848804e-5
GO:0007292	female gamete generation	4.908138e-5
GO:0038003	opioid receptor signaling pathway	4.936786e-5
GO:0006629	lipid metabolic process	4.993196e-5
GO:0018149	peptide cross-linking	5.014018e-5
GO:0002455	humoral immune response mediated by circulating immunoglobulin	5.138595e-5
GO:0030814	regulation of cAMP metabolic process	5.158163e-5
GO:0019216	regulation of lipid metabolic process	5.162478e-5
GO:0031281	positive regulation of cyclase activity	5.493730e-5
GO:0051349	positive regulation of lyase activity	5.691214e-5
GO:0070661	leukocyte proliferation	5.763747e-5
GO:0043162	ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway	5.853829e-5
GO:0010034	response to acetate	5.853829e-5
GO:0042108	positive regulation of cytokine biosynthetic process	6.050085e-5
GO:0048469	cell maturation	6.179853e-5
GO:2000191	regulation of fatty acid transport	6.222136e-5
GO:0009894	regulation of catabolic process	6.224827e-5
GO:0071260	cellular response to mechanical stimulus	6.348725e-5
GO:0002460	adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains	6.433129e-5
GO:0010574	regulation of vascular endothelial growth factor production	6.457006e-5
GO:0070201	regulation of establishment of protein localization	6.723012e-5
GO:0010639	negative regulation of organelle organization	6.926022e-5
GO:0070163	regulation of adiponectin secretion	6.995524e-5
GO:0030728	ovulation	7.125637e-5
GO:0033617	mitochondrial respiratory chain complex IV assembly	7.153544e-5
GO:0050727	regulation of inflammatory response	7.175597e-5
GO:0060429	epithelium development	7.175955e-5
GO:0071310	cellular response to organic substance	7.200653e-5
GO:0045762	positive regulation of adenylate cyclase activity	7.223118e-5
GO:0048709	oligodendrocyte differentiation	7.387318e-5
GO:0001525	angiogenesis	7.431879e-5
GO:0009410	response to xenobiotic stimulus	7.443467e-5
GO:0043085	positive regulation of catalytic activity	7.484146e-5
GO:0006620	posttranslational protein targeting to membrane	7.528042e-5
GO:0042512	negative regulation of tyrosine phosphorylation of Stat1 protein	7.528042e-5
GO:0015966	diadenosine tetraphosphate biosynthetic process	7.659548e-5
GO:0071345	cellular response to cytokine stimulus	8.131703e-5
GO:0032066	nucleolus to nucleoplasm transport	8.179299e-5
GO:0070105	positive regulation of interleukin-6-mediated signaling pathway	8.179299e-5
GO:0071675	regulation of mononuclear cell migration	8.234875e-5
GO:0019932	second-messenger-mediated signaling	8.308609e-5
GO:0007289	spermatid nucleus differentiation	8.350849e-5
GO:0042574	retinal metabolic process	8.551227e-5
GO:0043374	CD8-positive, alpha-beta T cell differentiation	8.735758e-5
GO:0021553	olfactory nerve development	9.485714e-5
GO:0051050	positive regulation of transport	1.007892e-4
GO:0033043	regulation of organelle organization	1.027293e-4
GO:0043001	Golgi to plasma membrane protein transport	1.028954e-4
GO:0010823	negative regulation of mitochondrion organization	1.028954e-4
GO:0030817	regulation of cAMP biosynthetic process	1.029740e-4
GO:0010759	positive regulation of macrophage chemotaxis	1.033210e-4
GO:0006954	inflammatory response	1.048397e-4
GO:0051240	positive regulation of multicellular organismal process	1.083047e-4
GO:0048293	regulation of isotype switching to IgE isotypes	1.108608e-4
GO:0007600	sensory perception	1.120052e-4
GO:0032231	regulation of actin filament bundle assembly	1.135563e-4
GO:0010951	negative regulation of endopeptidase activity	1.136103e-4
GO:0002250	adaptive immune response	1.163697e-4
GO:0071712	ER-associated misfolded protein catabolic process	1.178129e-4
GO:0050778	positive regulation of immune response	1.183146e-4
GO:0030802	regulation of cyclic nucleotide biosynthetic process	1.209716e-4
GO:0009146	purine nucleoside triphosphate catabolic process	1.266802e-4
GO:0010466	negative regulation of peptidase activity	1.286823e-4
GO:0002829	negative regulation of type 2 immune response	1.290102e-4
GO:0002689	negative regulation of leukocyte chemotaxis	1.290102e-4
GO:0046826	negative regulation of protein export from nucleus	1.290689e-4
GO:0032880	regulation of protein localization	1.303233e-4
GO:0052548	regulation of endopeptidase activity	1.334983e-4
GO:0051492	regulation of stress fiber assembly	1.367174e-4
GO:0060043	regulation of cardiac muscle cell proliferation	1.374779e-4
GO:0046825	regulation of protein export from nucleus	1.388462e-4
GO:0071897	DNA biosynthetic process	1.406423e-4
GO:0030098	lymphocyte differentiation	1.419389e-4
GO:0050922	negative regulation of chemotaxis	1.422312e-4
GO:0006097	glyoxylate cycle	1.445696e-4
GO:0006959	humoral immune response	1.463496e-4
GO:0018879	biphenyl metabolic process	1.479341e-4
GO:0006921	cellular component disassembly involved in apoptosis	1.494100e-4
GO:0031349	positive regulation of defense response	1.494637e-4
GO:0043316	cytotoxic T cell degranulation	1.521503e-4
GO:0006911	phagocytosis, engulfment	1.536109e-4
GO:0030432	peristalsis	1.554852e-4
GO:0040011	locomotion	1.602386e-4
GO:0010754	negative regulation of cGMP-mediated signaling	1.616628e-4
GO:0043652	engulfment of apoptotic cell	1.616628e-4
GO:0002605	negative regulation of dendritic cell antigen processing and presentation	1.616628e-4
GO:0010751	negative regulation of nitric oxide mediated signal transduction	1.616628e-4
GO:0002581	negative regulation of antigen processing and presentation of peptide or polysaccharide antigen via MHC class II	1.616628e-4
GO:0043242	negative regulation of protein complex disassembly	1.639800e-4
GO:0050795	regulation of behavior	1.647141e-4
GO:0006426	glycyl-tRNA aminoacylation	1.669895e-4
GO:0002822	regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains	1.675263e-4
GO:0046677	response to antibiotic	1.713892e-4
GO:0030593	neutrophil chemotaxis	1.731743e-4
GO:0009143	nucleoside triphosphate catabolic process	1.751162e-4
GO:0001568	blood vessel development	1.781441e-4
GO:0033600	negative regulation of mammary gland epithelial cell proliferation	1.797068e-4
GO:0010758	regulation of macrophage chemotaxis	1.803509e-4
GO:0009207	purine ribonucleoside triphosphate catabolic process	1.814050e-4
GO:0002253	activation of immune response	1.841635e-4
GO:0051094	positive regulation of developmental process	1.845876e-4
GO:0033124	regulation of GTP catabolic process	1.854985e-4
GO:0009605	response to external stimulus	1.965104e-4
GO:0071285	cellular response to lithium ion	1.968839e-4
GO:0032989	cellular component morphogenesis	1.985838e-4
GO:0035338	long-chain fatty-acyl-CoA biosynthetic process	1.994458e-4
GO:0002673	regulation of acute inflammatory response	2.008070e-4
GO:0090267	positive regulation of mitotic cell cycle spindle assembly checkpoint	2.040083e-4
GO:0050996	positive regulation of lipid catabolic process	2.080974e-4
GO:0048537	mucosal-associated lymphoid tissue development	2.105081e-4
GO:0010033	response to organic substance	2.258899e-4
GO:0030300	regulation of intestinal cholesterol absorption	2.294108e-4
GO:0060355	positive regulation of cell adhesion molecule production	2.346430e-4
GO:0070164	negative regulation of adiponectin secretion	2.346430e-4
GO:0035505	positive regulation of myosin light chain kinase activity	2.346430e-4
GO:0006725	cellular aromatic compound metabolic process	2.396671e-4
GO:0051493	regulation of cytoskeleton organization	2.433572e-4
GO:0001754	eye photoreceptor cell differentiation	2.468054e-4
GO:0071639	positive regulation of monocyte chemotactic protein-1 production	2.493488e-4
GO:0048585	negative regulation of response to stimulus	2.503342e-4
GO:0032731	positive regulation of interleukin-1 beta production	2.628876e-4
GO:0002696	positive regulation of leukocyte activation	2.650831e-4
GO:0048514	blood vessel morphogenesis	2.677616e-4
GO:0040009	regulation of growth rate	2.694561e-4
GO:0016052	carbohydrate catabolic process	2.739175e-4
GO:0001944	vasculature development	2.746233e-4
GO:0046326	positive regulation of glucose import	2.852337e-4
GO:0016486	peptide hormone processing	2.888290e-4
GO:0034589	hydroxyproline transport	2.895110e-4
GO:0000958	mitochondrial mRNA catabolic process	2.895110e-4
GO:0015826	threonine transport	2.895110e-4
GO:0000965	mitochondrial RNA 3'-end processing	2.895110e-4
GO:0000962	positive regulation of mitochondrial RNA catabolic process	2.895110e-4
GO:0045796	negative regulation of intestinal cholesterol absorption	3.004303e-4
GO:0010949	negative regulation of intestinal phytosterol absorption	3.004303e-4
GO:0048741	skeletal muscle fiber development	3.040775e-4
GO:0043087	regulation of GTPase activity	3.042175e-4
GO:0048878	chemical homeostasis	3.061297e-4
GO:0032713	negative regulation of interleukin-4 production	3.145816e-4
GO:0017085	response to insecticide	3.178340e-4
GO:0060847	endothelial cell fate specification	3.313652e-4
GO:0050920	regulation of chemotaxis	3.319699e-4
GO:0001659	temperature homeostasis	3.351513e-4
GO:0007189	activation of adenylate cyclase activity by G-protein signaling pathway	3.376401e-4
GO:2000116	regulation of cysteine-type endopeptidase activity	3.385271e-4
GO:0030182	neuron differentiation	3.482698e-4
GO:0007155	cell adhesion	3.517396e-4
GO:0006637	acyl-CoA metabolic process	3.523195e-4
GO:0046949	fatty-acyl-CoA biosynthetic process	3.568882e-4
GO:0032369	negative regulation of lipid transport	3.635196e-4
GO:0031058	positive regulation of histone modification	3.637077e-4
GO:0051930	regulation of sensory perception of pain	3.691055e-4
GO:0006082	organic acid metabolic process	3.707936e-4
GO:0000902	cell morphogenesis	3.726398e-4
GO:0006014	D-ribose metabolic process	3.727702e-4
GO:0008283	cell proliferation	3.731723e-4
GO:0050867	positive regulation of cell activation	3.758537e-4
GO:0002711	positive regulation of T cell mediated immunity	3.799656e-4
GO:0031536	positive regulation of exit from mitosis	3.843169e-4
GO:0014050	negative regulation of glutamate secretion	3.894053e-4
GO:0048592	eye morphogenesis	3.929825e-4
GO:0051130	positive regulation of cellular component organization	3.936005e-4
GO:0046415	urate metabolic process	3.944918e-4
GO:0051346	negative regulation of hydrolase activity	3.965892e-4
GO:0022409	positive regulation of cell-cell adhesion	4.007124e-4
GO:0031279	regulation of cyclase activity	4.012077e-4
GO:0034201	response to oleic acid	4.121104e-4
GO:0019725	cellular homeostasis	4.191230e-4
GO:0030855	epithelial cell differentiation	4.338901e-4
GO:0031424	keratinization	4.359952e-4
GO:0044057	regulation of system process	4.370504e-4
GO:0009154	purine ribonucleotide catabolic process	4.392294e-4
GO:0071229	cellular response to acid	4.422112e-4
GO:0031329	regulation of cellular catabolic process	4.447376e-4
GO:0045017	glycerolipid biosynthetic process	4.460033e-4
GO:0006950	response to stress	4.510158e-4
GO:0044087	regulation of cellular component biogenesis	4.544011e-4
GO:0048646	anatomical structure formation involved in morphogenesis	4.577460e-4
GO:0032725	positive regulation of granulocyte macrophage colony-stimulating factor production	4.624668e-4
GO:0001910	regulation of leukocyte mediated cytotoxicity	4.640137e-4
GO:0015959	diadenosine polyphosphate metabolic process	4.641558e-4
GO:0055021	regulation of cardiac muscle tissue growth	4.692867e-4
GO:0060022	hard palate development	4.721004e-4
GO:0035036	sperm-egg recognition	4.924212e-4
GO:0051339	regulation of lyase activity	4.998492e-4
GO:0033129	positive regulation of histone phosphorylation	5.019513e-4
GO:0009261	ribonucleotide catabolic process	5.054336e-4
GO:0007188	G-protein signaling, coupled to cAMP nucleotide second messenger	5.110655e-4
GO:0009408	response to heat	5.208829e-4
GO:0046883	regulation of hormone secretion	5.218606e-4
GO:0046530	photoreceptor cell differentiation	5.266405e-4
GO:0046473	phosphatidic acid metabolic process	5.319590e-4
GO:0035284	brain segmentation	5.366899e-4
GO:0007187	G-protein signaling, coupled to cyclic nucleotide second messenger	5.421336e-4
GO:0042851	L-alanine metabolic process	5.477952e-4
GO:0045087	innate immune response	5.547531e-4
GO:0022603	regulation of anatomical structure morphogenesis	5.567446e-4
GO:0000904	cell morphogenesis involved in differentiation	5.610546e-4
GO:0006066	alcohol metabolic process	5.610688e-4
GO:0045047	protein targeting to ER	5.640255e-4
GO:0030212	hyaluronan metabolic process	5.648414e-4
GO:0030837	negative regulation of actin filament polymerization	5.677176e-4
GO:0015825	L-serine transport	5.738204e-4
GO:0051835	positive regulation of synapse structural plasticity	5.803689e-4
GO:0043163	cell envelope organization	5.803689e-4
GO:0008616	queuosine biosynthetic process	5.861770e-4
GO:0032956	regulation of actin cytoskeleton organization	5.872861e-4
GO:0043281	regulation of cysteine-type endopeptidase activity involved in apoptotic process	5.919261e-4
GO:0007528	neuromuscular junction development	6.005991e-4
GO:0023057	negative regulation of signaling	6.084468e-4
GO:0051574	positive regulation of histone H3-K9 methylation	6.166346e-4
GO:0044085	cellular component biogenesis	6.181023e-4
GO:0007026	negative regulation of microtubule depolymerization	6.195709e-4
GO:0022607	cellular component assembly	6.283883e-4
GO:0032910	regulation of transforming growth factor beta3 production	6.323754e-4
GO:0060695	negative regulation of cholesterol transporter activity	6.388101e-4
GO:0010648	negative regulation of cell communication	6.410094e-4
GO:0015698	inorganic anion transport	6.416939e-4
GO:0032103	positive regulation of response to external stimulus	6.471053e-4
GO:0002819	regulation of adaptive immune response	6.526804e-4
GO:0032854	positive regulation of Rap GTPase activity	6.568623e-4
GO:0048871	multicellular organismal homeostasis	6.584919e-4
GO:0060045	positive regulation of cardiac muscle cell proliferation	6.737941e-4
GO:0071236	cellular response to antibiotic	6.747661e-4
GO:0045760	positive regulation of action potential	6.747661e-4
GO:0051049	regulation of transport	6.774452e-4
GO:0090004	positive regulation of establishment of protein localization in plasma membrane	6.858265e-4
GO:0045761	regulation of adenylate cyclase activity	6.949107e-4
GO:0033632	regulation of cell-cell adhesion mediated by integrin	7.036661e-4
GO:0045646	regulation of erythrocyte differentiation	7.118131e-4
GO:0045161	neuronal ion channel clustering	7.224282e-4
GO:0009628	response to abiotic stimulus	7.227975e-4
GO:0040037	negative regulation of fibroblast growth factor receptor signaling pathway	7.268046e-4
GO:0032763	regulation of mast cell cytokine production	7.360318e-4
GO:0048041	focal adhesion assembly	7.466628e-4
GO:0009056	catabolic process	7.563061e-4
GO:0071637	regulation of monocyte chemotactic protein-1 production	7.849820e-4
GO:0002684	positive regulation of immune system process	8.143269e-4
GO:0046631	alpha-beta T cell activation	8.478384e-4
GO:0034340	response to type I interferon	8.532271e-4
GO:0032673	regulation of interleukin-4 production	8.917342e-4
GO:0052547	regulation of peptidase activity	8.957542e-4
GO:0010638	positive regulation of organelle organization	9.157401e-4
GO:0045070	positive regulation of viral genome replication	9.310412e-4
GO:0007214	gamma-aminobutyric acid signaling pathway	9.419214e-4
GO:0048541	Peyer's patch development	9.499197e-4
GO:0007193	inhibition of adenylate cyclase activity by G-protein signaling pathway	9.576791e-4
GO:0016337	cell-cell adhesion	9.604378e-4
GO:0006032	chitin catabolic process	1.000644e-3
GO:0051345	positive regulation of hydrolase activity	1.014425e-3
GO:0034764	positive regulation of transmembrane transport	1.016193e-3
GO:0042127	regulation of cell proliferation	1.028011e-3
GO:0006461	protein complex assembly	1.029783e-3
GO:0006575	cellular modified amino acid metabolic process	1.033117e-3
GO:0050919	negative chemotaxis	1.040174e-3
GO:0006195	purine nucleotide catabolic process	1.044675e-3
GO:0000731	DNA synthesis involved in DNA repair	1.047553e-3
GO:0048519	negative regulation of biological process	1.052366e-3
GO:0007416	synapse assembly	1.053196e-3
GO:0070271	protein complex biogenesis	1.054358e-3
GO:0032743	positive regulation of interleukin-2 production	1.066957e-3
GO:0001666	response to hypoxia	1.068470e-3
GO:0051704	multi-organism process	1.092140e-3
GO:0031114	regulation of microtubule depolymerization	1.092349e-3
GO:0019693	ribose phosphate metabolic process	1.114487e-3
GO:0060166	olfactory pit development	1.123082e-3
GO:0019695	choline metabolic process	1.128665e-3
GO:0006893	Golgi to plasma membrane transport	1.147636e-3
GO:0016525	negative regulation of angiogenesis	1.153906e-3
GO:0034762	regulation of transmembrane transport	1.157964e-3
GO:0060326	cell chemotaxis	1.172669e-3
GO:0021514	ventral spinal cord interneuron differentiation	1.180470e-3
GO:0002443	leukocyte mediated immunity	1.183489e-3
GO:0051495	positive regulation of cytoskeleton organization	1.184032e-3
GO:0007268	synaptic transmission	1.185015e-3
GO:0045647	negative regulation of erythrocyte differentiation	1.197389e-3
GO:0055082	cellular chemical homeostasis	1.201314e-3
GO:0051129	negative regulation of cellular component organization	1.215353e-3
GO:0044255	cellular lipid metabolic process	1.223781e-3
GO:0031644	regulation of neurological system process	1.225829e-3
GO:0007204	elevation of cytosolic calcium ion concentration	1.231839e-3
GO:0010755	regulation of plasminogen activation	1.270994e-3
GO:0045408	regulation of interleukin-6 biosynthetic process	1.290154e-3
GO:0051051	negative regulation of transport	1.290445e-3
GO:0042063	gliogenesis	1.294590e-3
GO:0042307	positive regulation of protein import into nucleus	1.304229e-3
GO:0006680	glucosylceramide catabolic process	1.316911e-3

GREAT analysis results for mouseGenomic Enrichment of Annotations Tool (GREAT, Nat Biotechnol. 2010 May;28(5):495-501) is used to identify, both in human and in mouse, the gene ontology terms of biological processes enriched given the predicted TFBSs, and evaluated the overlap in the top-500 gene ontology terms between human and mouse. For each novel motif, the P value for the overlap was then evaluated by calculating its relative rank with respect to this background distribution.<br>Analyst: Michiel de Hoon <br><br>link to source dataset <br>data

---

GO ID	GO Term	p-value
GO:0046627	negative regulation of insulin receptor signaling pathway	1.282270e-15
GO:0050896	response to stimulus	9.924003e-13
GO:0035802	adrenal cortex formation	9.367306e-12
GO:0051180	vitamin transport	1.084091e-11
GO:0046626	regulation of insulin receptor signaling pathway	9.804896e-11
GO:0006950	response to stress	8.030283e-10
GO:0032846	positive regulation of homeostatic process	1.484203e-9
GO:0031100	organ regeneration	1.912120e-9
GO:0070168	negative regulation of biomineral tissue development	2.713651e-9
GO:0072302	negative regulation of metanephric glomerular mesangial cell proliferation	4.578375e-9
GO:2001076	positive regulation of metanephric ureteric bud development	4.578375e-9
GO:0007356	thorax and anterior abdomen determination	4.578375e-9
GO:0030279	negative regulation of ossification	6.231913e-9
GO:0048814	regulation of dendrite morphogenesis	1.324128e-8
GO:0030502	negative regulation of bone mineralization	1.513529e-8
GO:0032501	multicellular organismal process	1.770830e-8
GO:0032502	developmental process	2.434902e-8
GO:0031099	regeneration	3.649988e-8
GO:0072284	metanephric S-shaped body morphogenesis	5.012883e-8
GO:0072278	metanephric comma-shaped body morphogenesis	5.012883e-8
GO:0023052	signaling	8.065820e-8
GO:0050773	regulation of dendrite development	9.031383e-8
GO:0048583	regulation of response to stimulus	9.576017e-8
GO:0007185	transmembrane receptor protein tyrosine phosphatase signaling pathway	1.126985e-7
GO:0007154	cell communication	1.500891e-7
GO:0007354	zygotic determination of anterior/posterior axis, embryo	1.841700e-7
GO:0045780	positive regulation of bone resorption	1.882004e-7
GO:0060923	cardiac muscle cell fate commitment	2.036609e-7
GO:0010902	positive regulation of very-low-density lipoprotein particle remodeling	2.613894e-7
GO:0006952	defense response	2.986983e-7
GO:0007275	multicellular organismal development	3.251832e-7
GO:0001542	ovulation from ovarian follicle	3.463273e-7
GO:0046649	lymphocyte activation	3.654545e-7
GO:0048856	anatomical structure development	3.947620e-7
GO:0006420	arginyl-tRNA aminoacylation	4.942287e-7
GO:0045807	positive regulation of endocytosis	5.025633e-7
GO:0006955	immune response	6.068436e-7
GO:0010873	positive regulation of cholesterol esterification	6.502125e-7
GO:0042448	progesterone metabolic process	6.577852e-7
GO:0034105	positive regulation of tissue remodeling	8.577611e-7
GO:0002376	immune system process	9.412014e-7
GO:0010872	regulation of cholesterol esterification	9.453399e-7
GO:0045065	cytotoxic T cell differentiation	1.015930e-6
GO:0010951	negative regulation of endopeptidase activity	1.280619e-6
GO:0070837	dehydroascorbic acid transport	1.339896e-6
GO:0050766	positive regulation of phagocytosis	1.426795e-6
GO:0072166	posterior mesonephric tubule development	1.470166e-6
GO:0009258	10-formyltetrahydrofolate catabolic process	1.624850e-6
GO:0045911	positive regulation of DNA recombination	2.178885e-6
GO:0030728	ovulation	2.179367e-6
GO:0045188	regulation of circadian sleep/wake cycle, non-REM sleep	2.194659e-6
GO:0031640	killing of cells of other organism	2.215504e-6
GO:0051239	regulation of multicellular organismal process	2.797533e-6
GO:0072301	regulation of metanephric glomerular mesangial cell proliferation	3.029566e-6
GO:0048731	system development	3.103538e-6
GO:0002077	acrosome matrix dispersal	3.192638e-6
GO:0046010	positive regulation of circadian sleep/wake cycle, non-REM sleep	3.496462e-6
GO:0051716	cellular response to stimulus	3.984246e-6
GO:0051240	positive regulation of multicellular organismal process	4.229893e-6
GO:0048584	positive regulation of response to stimulus	4.298541e-6
GO:0002385	mucosal immune response	4.973526e-6
GO:0034370	triglyceride-rich lipoprotein particle remodeling	5.897979e-6
GO:0051883	killing of cells in other organism involved in symbiotic interaction	5.897979e-6
GO:0032957	inositol trisphosphate metabolic process	6.547369e-6
GO:0006982	response to lipid hydroperoxide	6.720784e-6
GO:0060539	diaphragm development	7.777949e-6
GO:0010898	positive regulation of triglyceride catabolic process	7.789745e-6
GO:0050775	positive regulation of dendrite morphogenesis	8.525678e-6
GO:0001944	vasculature development	8.788784e-6
GO:0046850	regulation of bone remodeling	9.075072e-6
GO:0019430	removal of superoxide radicals	9.108173e-6
GO:0002251	organ or tissue specific immune response	9.292100e-6
GO:0044243	multicellular organismal catabolic process	9.331399e-6
GO:0000305	response to oxygen radical	9.352343e-6
GO:0072539	T-helper 17 cell differentiation	9.784431e-6
GO:0001516	prostaglandin biosynthetic process	9.888913e-6
GO:0019836	hemolysis by symbiont of host erythrocytes	1.058248e-5
GO:0055090	acylglycerol homeostasis	1.061786e-5
GO:0007159	leukocyte cell-cell adhesion	1.066049e-5
GO:0001701	in utero embryonic development	1.102770e-5
GO:0032844	regulation of homeostatic process	1.124584e-5
GO:0018158	protein oxidation	1.142038e-5
GO:0033194	response to hydroperoxide	1.150232e-5
GO:0008595	anterior/posterior axis specification, embryo	1.387825e-5
GO:0045577	regulation of B cell differentiation	1.390244e-5
GO:0060397	JAK-STAT cascade involved in growth hormone signaling pathway	1.449478e-5
GO:0019371	cyclooxygenase pathway	1.590412e-5
GO:0007281	germ cell development	1.602837e-5
GO:0006633	fatty acid biosynthetic process	1.670361e-5
GO:0006953	acute-phase response	1.685248e-5
GO:0044003	modification by symbiont of host morphology or physiology	2.026607e-5
GO:0007165	signal transduction	2.047628e-5
GO:0042744	hydrogen peroxide catabolic process	2.118812e-5
GO:0060627	regulation of vesicle-mediated transport	2.146423e-5
GO:0048265	response to pain	2.256445e-5
GO:0032817	regulation of natural killer cell proliferation	2.473489e-5
GO:0014034	neural crest cell fate commitment	2.513400e-5
GO:0090050	positive regulation of cell migration involved in sprouting angiogenesis	2.515839e-5
GO:0050748	negative regulation of lipoprotein metabolic process	2.837833e-5
GO:0060421	positive regulation of heart growth	2.936633e-5
GO:0001568	blood vessel development	3.012197e-5
GO:0072273	metanephric nephron morphogenesis	3.057297e-5
GO:0045926	negative regulation of growth	3.325819e-5
GO:2000195	negative regulation of female gonad development	3.366799e-5
GO:0002440	production of molecular mediator of immune response	3.377899e-5
GO:0003006	developmental process involved in reproduction	3.397250e-5
GO:0060911	cardiac cell fate commitment	3.612009e-5
GO:0090074	negative regulation of protein homodimerization activity	3.815481e-5
GO:0051659	maintenance of mitochondrion location	3.843069e-5
GO:0042753	positive regulation of circadian rhythm	3.843069e-5
GO:0001658	branching involved in ureteric bud morphogenesis	4.041618e-5
GO:0023051	regulation of signaling	4.209327e-5
GO:0071436	sodium ion export	4.460615e-5
GO:0000462	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)	4.460615e-5
GO:0045321	leukocyte activation	4.481435e-5
GO:0051006	positive regulation of lipoprotein lipase activity	4.527183e-5
GO:2000020	positive regulation of male gonad development	4.936165e-5
GO:0048513	organ development	5.130514e-5
GO:0034103	regulation of tissue remodeling	5.382978e-5
GO:0050865	regulation of cell activation	5.409395e-5
GO:0040008	regulation of growth	5.416755e-5
GO:0072125	negative regulation of glomerular mesangial cell proliferation	5.600119e-5
GO:0090049	regulation of cell migration involved in sprouting angiogenesis	5.631098e-5
GO:0045938	positive regulation of circadian sleep/wake cycle, sleep	5.713468e-5
GO:0042346	positive regulation of NF-kappaB import into nucleus	5.861341e-5
GO:0019358	nicotinate nucleotide salvage	5.942473e-5
GO:0016337	cell-cell adhesion	5.970797e-5
GO:0048268	clathrin coat assembly	6.170400e-5
GO:0061032	visceral serous pericardium development	6.264916e-5
GO:0002526	acute inflammatory response	6.348027e-5
GO:0050746	regulation of lipoprotein metabolic process	6.624245e-5
GO:0030100	regulation of endocytosis	7.030475e-5
GO:0035095	behavioral response to nicotine	7.079931e-5
GO:0006901	vesicle coating	7.193737e-5
GO:0032733	positive regulation of interleukin-10 production	7.205091e-5
GO:0050668	positive regulation of homocysteine metabolic process	7.479944e-5
GO:0045963	negative regulation of dopamine metabolic process	7.479944e-5
GO:2000194	regulation of female gonad development	7.594919e-5
GO:0070904	transepithelial L-ascorbic acid transport	8.233239e-5
GO:0009311	oligosaccharide metabolic process	8.430967e-5
GO:0002227	innate immune response in mucosa	8.456088e-5
GO:0006760	folic acid-containing compound metabolic process	8.682744e-5
GO:0060395	SMAD protein signal transduction	8.763683e-5
GO:0035117	embryonic arm morphogenesis	8.841543e-5
GO:0051924	regulation of calcium ion transport	8.968929e-5
GO:0032879	regulation of localization	9.327315e-5
GO:0042345	regulation of NF-kappaB import into nucleus	9.442025e-5
GO:0090273	regulation of somatostatin secretion	9.620226e-5
GO:0035104	positive regulation of transcription via sterol regulatory element binding	9.771680e-5
GO:0030838	positive regulation of actin filament polymerization	9.961951e-5
GO:0042908	xenobiotic transport	1.011182e-4
GO:0048609	multicellular organismal reproductive process	1.027585e-4
GO:0006599	phosphagen metabolic process	1.053688e-4
GO:0044130	negative regulation of growth of symbiont in host	1.094845e-4
GO:0050996	positive regulation of lipid catabolic process	1.094845e-4
GO:0045830	positive regulation of isotype switching	1.111499e-4
GO:0070541	response to platinum ion	1.130037e-4
GO:0035590	purinergic nucleotide receptor signaling pathway	1.176437e-4
GO:0002694	regulation of leukocyte activation	1.181768e-4
GO:0006471	protein ADP-ribosylation	1.201460e-4
GO:2000271	positive regulation of fibroblast apoptosis	1.237820e-4
GO:2000270	negative regulation of fibroblast apoptosis	1.237820e-4
GO:0044345	stromal-epithelial cell signaling involved in prostate gland development	1.237820e-4
GO:2000080	negative regulation of canonical Wnt receptor signaling pathway involved in controlling type B pancreatic cell proliferation	1.237820e-4
GO:0045578	negative regulation of B cell differentiation	1.246330e-4
GO:0014043	negative regulation of neuron maturation	1.246330e-4
GO:0051657	maintenance of organelle location	1.296038e-4
GO:0060137	maternal process involved in parturition	1.310665e-4
GO:0009408	response to heat	1.351909e-4
GO:0002377	immunoglobulin production	1.373161e-4
GO:0006941	striated muscle contraction	1.392892e-4
GO:0048266	behavioral response to pain	1.399644e-4
GO:0060732	positive regulation of inositol phosphate biosynthetic process	1.407809e-4
GO:0006693	prostaglandin metabolic process	1.434592e-4
GO:0042110	T cell activation	1.469487e-4
GO:0034445	negative regulation of plasma lipoprotein particle oxidation	1.499287e-4
GO:0043903	regulation of symbiosis, encompassing mutualism through parasitism	1.520197e-4
GO:0006713	glucocorticoid catabolic process	1.568136e-4
GO:0050795	regulation of behavior	1.592927e-4
GO:0051176	positive regulation of sulfur metabolic process	1.630765e-4
GO:0043901	negative regulation of multi-organism process	1.645191e-4
GO:0003166	bundle of His development	1.798484e-4
GO:0009611	response to wounding	1.838503e-4
GO:0010919	regulation of inositol phosphate biosynthetic process	1.940884e-4
GO:2000079	regulation of canonical Wnt receptor signaling pathway involved in controlling type B pancreatic cell proliferation	1.958985e-4
GO:0071380	cellular response to prostaglandin E stimulus	1.958985e-4
GO:0006994	positive regulation of transcription via sterol regulatory element binding involved in ER-nuclear sterol response pathway	1.958985e-4
GO:0000303	response to superoxide	1.963600e-4
GO:0003161	cardiac conduction system development	1.972523e-4
GO:0050850	positive regulation of calcium-mediated signaling	1.986530e-4
GO:0034372	very-low-density lipoprotein particle remodeling	1.993279e-4
GO:0045124	regulation of bone resorption	2.027594e-4
GO:0033600	negative regulation of mammary gland epithelial cell proliferation	2.061984e-4
GO:0072015	glomerular visceral epithelial cell development	2.128582e-4
GO:0014029	neural crest formation	2.128582e-4
GO:0030278	regulation of ossification	2.163602e-4
GO:0070389	chaperone cofactor-dependent protein refolding	2.176597e-4
GO:0033239	negative regulation of cellular amine metabolic process	2.176597e-4
GO:0061008	hepaticobiliary system development	2.220528e-4
GO:0051127	positive regulation of actin nucleation	2.233292e-4
GO:0019953	sexual reproduction	2.281449e-4
GO:0001889	liver development	2.373299e-4
GO:0048610	cellular process involved in reproduction	2.391434e-4
GO:0072124	regulation of glomerular mesangial cell proliferation	2.428466e-4
GO:0006810	transport	2.451084e-4
GO:0043647	inositol phosphate metabolic process	2.471600e-4
GO:0002639	positive regulation of immunoglobulin production	2.496718e-4
GO:0002683	negative regulation of immune system process	2.502506e-4
GO:0001775	cell activation	2.524522e-4
GO:0010033	response to organic substance	2.540280e-4
GO:0034442	regulation of lipoprotein oxidation	2.552720e-4
GO:0051234	establishment of localization	2.556599e-4
GO:0030574	collagen catabolic process	2.558262e-4
GO:0008284	positive regulation of cell proliferation	2.558577e-4
GO:0014829	vascular smooth muscle contraction	2.561432e-4
GO:0060231	mesenchymal to epithelial transition	2.626745e-4
GO:0060136	embryonic process involved in female pregnancy	2.641764e-4
GO:2000018	regulation of male gonad development	2.641764e-4
GO:0060133	somatotropin secreting cell development	2.714882e-4
GO:0034553	mitochondrial respiratory chain complex II assembly	2.714882e-4
GO:0010845	positive regulation of reciprocal meiotic recombination	2.714882e-4
GO:0045187	regulation of circadian sleep/wake cycle, sleep	2.726864e-4
GO:0008207	C21-steroid hormone metabolic process	2.829022e-4
GO:0048304	positive regulation of isotype switching to IgG isotypes	2.901428e-4
GO:0015669	gas transport	2.910892e-4
GO:0006590	thyroid hormone generation	3.136061e-4
GO:0051049	regulation of transport	3.353976e-4
GO:0051607	defense response to virus	3.363508e-4
GO:0050764	regulation of phagocytosis	3.373273e-4
GO:0045137	development of primary sexual characteristics	3.419895e-4
GO:0001906	cell killing	3.455113e-4
GO:0007292	female gamete generation	3.489879e-4
GO:0007341	penetration of zona pellucida	3.552450e-4
GO:0009966	regulation of signal transduction	3.676079e-4
GO:0009948	anterior/posterior axis specification	3.731745e-4
GO:0051125	regulation of actin nucleation	3.747246e-4
GO:0007271	synaptic transmission, cholinergic	3.756613e-4
GO:2000466	negative regulation of glycogen (starch) synthase activity	3.776702e-4
GO:0006107	oxaloacetate metabolic process	3.924081e-4
GO:0072358	cardiovascular system development	3.962670e-4
GO:0002706	regulation of lymphocyte mediated immunity	3.978943e-4
GO:0045588	positive regulation of gamma-delta T cell differentiation	4.076797e-4
GO:0042993	positive regulation of transcription factor import into nucleus	4.099524e-4
GO:0045663	positive regulation of myoblast differentiation	4.132142e-4
GO:0042127	regulation of cell proliferation	4.188453e-4
GO:0045766	positive regulation of angiogenesis	4.204986e-4
GO:0065007	biological regulation	4.207469e-4
GO:0006103	2-oxoglutarate metabolic process	4.280693e-4
GO:0007167	enzyme linked receptor protein signaling pathway	4.343493e-4
GO:0050727	regulation of inflammatory response	4.361813e-4
GO:0048537	mucosal-associated lymphoid tissue development	4.376866e-4
GO:0010591	regulation of lamellipodium assembly	4.376866e-4
GO:0006688	glycosphingolipid biosynthetic process	4.386396e-4
GO:0090362	positive regulation of platelet-derived growth factor production	4.429590e-4
GO:0090336	positive regulation of brown fat cell differentiation	4.429590e-4
GO:0008208	C21-steroid hormone catabolic process	4.429590e-4
GO:0090271	positive regulation of fibroblast growth factor production	4.429590e-4
GO:0016192	vesicle-mediated transport	4.432817e-4
GO:0008054	cyclin catabolic process	4.436484e-4
GO:0048514	blood vessel morphogenesis	4.547112e-4
GO:0007276	gamete generation	4.560001e-4
GO:0060762	regulation of branching involved in mammary gland duct morphogenesis	4.722572e-4
GO:0009247	glycolipid biosynthetic process	4.878516e-4
GO:0007585	respiratory gaseous exchange	4.968098e-4
GO:0042221	response to chemical stimulus	5.000501e-4
GO:0010896	regulation of triglyceride catabolic process	5.087787e-4
GO:0035645	enteric smooth muscle cell differentiation	5.166526e-4
GO:0007497	posterior midgut development	5.166526e-4
GO:0014041	regulation of neuron maturation	5.242774e-4
GO:2000653	regulation of genetic imprinting	5.347088e-4
GO:0015670	carbon dioxide transport	5.384466e-4
GO:0006491	N-glycan processing	5.422706e-4
GO:0035360	positive regulation of peroxisome proliferator activated receptor signaling pathway	5.808050e-4
GO:0006888	ER to Golgi vesicle-mediated transport	5.827992e-4
GO:0003338	metanephros morphogenesis	5.849731e-4
GO:0006954	inflammatory response	6.275244e-4
GO:0060540	diaphragm morphogenesis	6.303845e-4
GO:0060464	lung lobe formation	6.303845e-4
GO:0035589	G-protein coupled purinergic nucleotide receptor signaling pathway	6.341216e-4
GO:0001910	regulation of leukocyte mediated cytotoxicity	6.500371e-4
GO:0032819	positive regulation of natural killer cell proliferation	6.654999e-4
GO:0022412	cellular process involved in reproduction in multicellular organism	6.690176e-4
GO:0001912	positive regulation of leukocyte mediated cytotoxicity	6.720083e-4
GO:0032962	positive regulation of inositol trisphosphate biosynthetic process	6.768602e-4
GO:0046070	dGTP metabolic process	6.768602e-4
GO:0061002	negative regulation of dendritic spine morphogenesis	6.768602e-4
GO:0045338	farnesyl diphosphate metabolic process	6.768602e-4
GO:0048520	positive regulation of behavior	6.804951e-4
GO:0010646	regulation of cell communication	6.813925e-4
GO:0051050	positive regulation of transport	6.869770e-4
GO:0007517	muscle organ development	6.893208e-4
GO:0002682	regulation of immune system process	6.895765e-4
GO:0048646	anatomical structure formation involved in morphogenesis	6.927197e-4
GO:0003171	atrioventricular valve development	7.009014e-4
GO:0031347	regulation of defense response	7.036377e-4
GO:0002381	immunoglobulin production involved in immunoglobulin mediated immune response	7.186877e-4
GO:0019233	sensory perception of pain	7.339558e-4
GO:0007166	cell surface receptor linked signaling pathway	7.349815e-4
GO:0090208	positive regulation of triglyceride metabolic process	7.393165e-4
GO:0000003	reproduction	7.578737e-4
GO:0000090	mitotic anaphase	7.701782e-4
GO:0016973	poly(A)+ mRNA export from nucleus	7.701782e-4
GO:0030490	maturation of SSU-rRNA	7.718836e-4
GO:0014821	phasic smooth muscle contraction	7.890195e-4
GO:0034435	cholesterol esterification	7.983396e-4
GO:0043496	regulation of protein homodimerization activity	8.041051e-4
GO:0070167	regulation of biomineral tissue development	8.116879e-4
GO:2000026	regulation of multicellular organismal development	8.342834e-4
GO:0033700	phospholipid efflux	8.590038e-4
GO:2000021	regulation of ion homeostasis	8.827485e-4
GO:0010592	positive regulation of lamellipodium assembly	8.907110e-4
GO:0061138	morphogenesis of a branching epithelium	8.926811e-4
GO:0060055	angiogenesis involved in wound healing	9.084909e-4
GO:0072050	S-shaped body morphogenesis	9.186267e-4
GO:0072049	comma-shaped body morphogenesis	9.186267e-4
GO:0015914	phospholipid transport	9.191714e-4
GO:0001657	ureteric bud development	9.211297e-4
GO:0072283	metanephric renal vesicle morphogenesis	9.304335e-4
GO:0035587	purinergic receptor signaling pathway	9.391836e-4
GO:0050871	positive regulation of B cell activation	9.434431e-4
GO:0002291	T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell	9.947117e-4
GO:0003181	atrioventricular valve morphogenesis	1.024126e-3
GO:0030500	regulation of bone mineralization	1.078773e-3
GO:0001892	embryonic placenta development	1.089905e-3
GO:0044106	cellular amine metabolic process	1.120339e-3
GO:0006939	smooth muscle contraction	1.124122e-3
GO:0060675	ureteric bud morphogenesis	1.127776e-3
GO:0032958	inositol phosphate biosynthetic process	1.139212e-3
GO:0002268	follicular dendritic cell differentiation	1.172359e-3
GO:0000578	embryonic axis specification	1.191330e-3
GO:0097039	protein linear polyubiquitination	1.195784e-3
GO:0072520	seminiferous tubule development	1.195784e-3
GO:0051383	kinetochore organization	1.203028e-3
GO:0030382	sperm mitochondrion organization	1.203028e-3
GO:0000132	establishment of mitotic spindle orientation	1.230413e-3
GO:0010901	regulation of very-low-density lipoprotein particle remodeling	1.244903e-3
GO:0000018	regulation of DNA recombination	1.290641e-3
GO:0035050	embryonic heart tube development	1.297228e-3
GO:0008202	steroid metabolic process	1.313832e-3
GO:0031341	regulation of cell killing	1.314068e-3
GO:0022414	reproductive process	1.319767e-3
GO:0043519	regulation of myosin II filament organization	1.344574e-3
GO:0070672	response to interleukin-15	1.344574e-3
GO:0043206	fibril organization	1.347317e-3
GO:0001893	maternal placenta development	1.361235e-3
GO:0014826	vein smooth muscle contraction	1.411945e-3
GO:0001911	negative regulation of leukocyte mediated cytotoxicity	1.445708e-3
GO:0033108	mitochondrial respiratory chain complex assembly	1.449067e-3
GO:0006600	creatine metabolic process	1.454014e-3
GO:0002456	T cell mediated immunity	1.455989e-3
GO:0006090	pyruvate metabolic process	1.465085e-3
GO:0046620	regulation of organ growth	1.466735e-3
GO:0006481	C-terminal protein methylation	1.480589e-3
GO:0000461	endonucleolytic cleavage to generate mature 3'-end of SSU-rRNA from (SSU-rRNA, 5.8S rRNA, LSU-rRNA)	1.480589e-3
GO:0000447	endonucleolytic cleavage in ITS1 to separate SSU-rRNA from 5.8S rRNA and LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)	1.480589e-3
GO:0031343	positive regulation of cell killing	1.503197e-3
GO:0008406	gonad development	1.505288e-3
GO:0046653	tetrahydrofolate metabolic process	1.529140e-3
GO:0070460	thyroid-stimulating hormone secretion	1.536673e-3
GO:0048738	cardiac muscle tissue development	1.540125e-3
GO:0060993	kidney morphogenesis	1.550327e-3
GO:0031342	negative regulation of cell killing	1.552960e-3
GO:0008594	photoreceptor cell morphogenesis	1.593210e-3
GO:0061011	hepatic duct development	1.593210e-3
GO:0051641	cellular localization	1.645424e-3
GO:0002920	regulation of humoral immune response	1.651090e-3
GO:0046394	carboxylic acid biosynthetic process	1.685661e-3
GO:0060158	activation of phospholipase C activity by dopamine receptor signaling pathway	1.697588e-3
GO:0042304	regulation of fatty acid biosynthetic process	1.713680e-3
GO:2000507	positive regulation of energy homeostasis	1.731189e-3
GO:0001831	trophectodermal cellular morphogenesis	1.731189e-3
GO:2000253	positive regulation of feeding behavior	1.731189e-3
GO:0009617	response to bacterium	1.740511e-3
GO:0044236	multicellular organismal metabolic process	1.750897e-3
GO:0071560	cellular response to transforming growth factor beta stimulus	1.774591e-3
GO:0010959	regulation of metal ion transport	1.820882e-3
GO:0022410	circadian sleep/wake cycle process	1.840016e-3
GO:0042113	B cell activation	1.853548e-3
GO:0033555	multicellular organismal response to stress	1.858823e-3
GO:0006730	one-carbon metabolic process	1.870367e-3
GO:0060262	negative regulation of N-terminal protein palmitoylation	1.915396e-3
GO:2000009	negative regulation of protein localization at cell surface	1.915396e-3
GO:0021771	lateral geniculate nucleus development	1.915396e-3
GO:0009443	pyridoxal 5'-phosphate salvage	1.915396e-3
GO:0040001	establishment of mitotic spindle localization	1.915592e-3
GO:0071214	cellular response to abiotic stimulus	1.937620e-3
GO:0033554	cellular response to stress	1.967185e-3
GO:0060537	muscle tissue development	1.983500e-3
GO:0030308	negative regulation of cell growth	1.985099e-3
GO:0002637	regulation of immunoglobulin production	1.999329e-3
GO:0031344	regulation of cell projection organization	2.031194e-3
GO:0051382	kinetochore assembly	2.071655e-3
GO:0060252	positive regulation of glial cell proliferation	2.081995e-3
GO:0016554	cytidine to uridine editing	2.086063e-3
GO:0006979	response to oxidative stress	2.104048e-3
GO:0051255	spindle midzone assembly	2.118740e-3
GO:0042592	homeostatic process	2.139374e-3
GO:0001710	mesodermal cell fate commitment	2.185653e-3
GO:0042840	D-glucuronate catabolic process	2.188875e-3
GO:0010667	negative regulation of cardiac muscle cell apoptosis	2.191717e-3
GO:0045747	positive regulation of Notch signaling pathway	2.198779e-3
GO:0051817	modification of morphology or physiology of other organism involved in symbiotic interaction	2.246621e-3
GO:0048535	lymph node development	2.246738e-3
GO:0072077	renal vesicle morphogenesis	2.269136e-3
GO:0071481	cellular response to X-ray	2.345221e-3
GO:0015884	folic acid transport	2.345221e-3
GO:0051649	establishment of localization in cell	2.368221e-3
GO:0048302	regulation of isotype switching to IgG isotypes	2.404990e-3
GO:0032101	regulation of response to external stimulus	2.411763e-3
GO:0046185	aldehyde catabolic process	2.419287e-3
GO:0005989	lactose biosynthetic process	2.446438e-3
GO:0046544	development of secondary male sexual characteristics	2.446438e-3
GO:0045579	positive regulation of B cell differentiation	2.450693e-3
GO:0009312	oligosaccharide biosynthetic process	2.465752e-3
GO:0060056	mammary gland involution	2.477415e-3
GO:0003229	ventricular cardiac muscle tissue development	2.514256e-3
GO:0050864	regulation of B cell activation	2.584066e-3
GO:0003283	atrial septum development	2.599006e-3
GO:0009719	response to endogenous stimulus	2.644347e-3
GO:0050789	regulation of biological process	2.662138e-3
GO:0009988	cell-cell recognition	2.699858e-3
GO:0050848	regulation of calcium-mediated signaling	2.720407e-3
GO:0009725	response to hormone stimulus	2.736791e-3
GO:0044281	small molecule metabolic process	2.737466e-3
GO:0060126	somatotropin secreting cell differentiation	2.741774e-3
GO:0045079	negative regulation of chemokine biosynthetic process	2.741774e-3
GO:0033128	negative regulation of histone phosphorylation	2.824722e-3
GO:0003094	glomerular filtration	2.824722e-3
GO:0042745	circadian sleep/wake cycle	2.874028e-3
GO:0032496	response to lipopolysaccharide	2.892201e-3
GO:0006936	muscle contraction	2.903496e-3
GO:0050866	negative regulation of cell activation	2.912642e-3
GO:0050432	catecholamine secretion	2.926073e-3
GO:0071257	cellular response to electrical stimulus	2.944010e-3
GO:0051179	localization	2.952309e-3
GO:0016553	base conversion or substitution editing	2.954591e-3
GO:0032864	activation of Cdc42 GTPase activity	2.954591e-3
GO:0032653	regulation of interleukin-10 production	2.976955e-3
GO:0007204	elevation of cytosolic calcium ion concentration	2.985564e-3
GO:0007163	establishment or maintenance of cell polarity	2.987364e-3
GO:0006575	cellular modified amino acid metabolic process	2.988536e-3
GO:0070669	response to interleukin-2	3.036297e-3
GO:0060022	hard palate development	3.047068e-3
GO:2000027	regulation of organ morphogenesis	3.113510e-3
GO:0010613	positive regulation of cardiac muscle hypertrophy	3.132606e-3
GO:0046651	lymphocyte proliferation	3.182134e-3
GO:0071305	cellular response to vitamin D	3.184392e-3
GO:0051891	positive regulation of cardioblast differentiation	3.184392e-3
GO:0019054	modulation by virus of host cellular process	3.210535e-3
GO:0001702	gastrulation with mouth forming second	3.369413e-3
GO:0009266	response to temperature stimulus	3.378531e-3
GO:0030098	lymphocyte differentiation	3.378537e-3
GO:0032259	methylation	3.390937e-3
GO:0072028	nephron morphogenesis	3.456666e-3
GO:0003218	cardiac left ventricle formation	3.488595e-3
GO:0001573	ganglioside metabolic process	3.513487e-3
GO:0032472	Golgi calcium ion transport	3.517247e-3
GO:0032468	Golgi calcium ion homeostasis	3.517247e-3
GO:0030026	cellular manganese ion homeostasis	3.517247e-3
GO:0060420	regulation of heart growth	3.525135e-3
GO:0046456	icosanoid biosynthetic process	3.540455e-3
GO:0050873	brown fat cell differentiation	3.540455e-3
GO:0002707	negative regulation of lymphocyte mediated immunity	3.546084e-3
GO:0009628	response to abiotic stimulus	3.594440e-3
GO:0018345	protein palmitoylation	3.595658e-3
GO:0001675	acrosome assembly	3.598207e-3
GO:0002252	immune effector process	3.638379e-3
GO:0071371	cellular response to gonadotropin stimulus	3.670112e-3
GO:0006344	maintenance of chromatin silencing	3.689123e-3
GO:2000522	positive regulation of immunological synapse formation	3.691243e-3
GO:0072500	negative regulation of transcription from RNA polymerase II promoter by nuclear hormone receptor	3.691243e-3
GO:0010918	positive regulation of mitochondrial membrane potential	3.691243e-3
GO:0050925	negative regulation of negative chemotaxis	3.731049e-3
GO:0048241	epinephrine transport	3.731070e-3
GO:0051004	regulation of lipoprotein lipase activity	3.735166e-3
GO:0000479	endonucleolytic cleavage of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)	3.765153e-3
GO:0001915	negative regulation of T cell mediated cytotoxicity	3.779006e-3
GO:0006900	membrane budding	3.811709e-3
GO:0048630	skeletal muscle tissue growth	3.812768e-3
GO:0006868	glutamine transport	3.812768e-3
GO:0045743	positive regulation of fibroblast growth factor receptor signaling pathway	3.820284e-3
GO:0035335	peptidyl-tyrosine dephosphorylation	3.827519e-3
GO:0019439	aromatic compound catabolic process	3.874073e-3
GO:0046622	positive regulation of organ growth	3.973917e-3
GO:0051249	regulation of lymphocyte activation	3.974832e-3
GO:0016310	phosphorylation	4.000181e-3
GO:0070849	response to epidermal growth factor stimulus	4.064082e-3
GO:0048242	epinephrine secretion	4.096357e-3
GO:0002689	negative regulation of leukocyte chemotaxis	4.096357e-3
GO:0042098	T cell proliferation	4.120886e-3
GO:0002820	negative regulation of adaptive immune response	4.126005e-3
GO:0090276	regulation of peptide hormone secretion	4.162827e-3
GO:0050796	regulation of insulin secretion	4.210090e-3
GO:0072511	divalent inorganic cation transport	4.231899e-3
GO:0010647	positive regulation of cell communication	4.293947e-3
GO:0001821	histamine secretion	4.318980e-3
GO:0050912	detection of chemical stimulus involved in sensory perception of taste	4.366347e-3
GO:2000117	negative regulation of cysteine-type endopeptidase activity	4.398476e-3
GO:0006520	cellular amino acid metabolic process	4.414776e-3
GO:0022603	regulation of anatomical structure morphogenesis	4.425143e-3