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{{MCL_coexpression_mm9
{
|coexpression_dpi_cluster_scores_mean=0.520918001481458

Latest revision as of 19:16, 17 September 2013


Phase1 CAGE Peaks

 Short description
Mm9::chr14:35315849..35315901,-p2@Bmpr1a
Mm9::chr8:131209774..131209811,+p3@Itgb1
Mm9::chr8:131209812..131209823,+p4@Itgb1


Enriched pathways on this co-expression cluster<b>Summary:</b><br>Canonical pathway gene sets were compiled from Reactome, Wikipathways and KEGG. For the major signaling pathways, the transcriptionally-regulated genes (downstream targets) were obtained from Netpath. Combined, the canonical pathways and downstream targets totaled 489 human gene sets. The corresponding M. musculus gene sets were inferred by homology using the HomoloGene database. Enrichment for each of the canonical 489 pathways and gene sets included in the co-expression cluster was assessed by the hypergeometric probability. The resulting P values were also then adjusted by the Benjamini-Hochberg method for multiple comparisons.<br><b>Analyst: </b>Emmanuel Dimont<br><br>link to source dataset<br>data

GO IDGO nameFDR corrected p-value
GO:0007507heart development0.00314103617670155
GO:0008284positive regulation of cell proliferation0.00314103617670155
GO:0042684cardioblast cell fate commitment0.00314103617670155
GO:0042685cardioblast cell fate specification0.00314103617670155
GO:0048382mesendoderm development0.00314103617670155
GO:0001880Mullerian duct regression0.00314103617670155
GO:0042127regulation of cell proliferation0.00628172816797938
GO:0010002cardioblast differentiation0.00628172816797938
GO:0060033anatomical structure regression0.00628172816797938
GO:0009950dorsal/ventral axis specification0.00753786729032103
GO:0008283cell proliferation0.00999617726056794
GO:0045214sarcomere organization0.0134564208330796
GO:0004675transmembrane receptor protein serine/threonine kinase activity0.0134564208330796
GO:0005024transforming growth factor beta receptor activity0.0134564208330796
GO:0031594neuromuscular junction0.0134564208330796
GO:0030239myofibril assembly0.0134564208330796
GO:0055002striated muscle cell development0.0134564208330796
GO:0048522positive regulation of cellular process0.0134564208330796
GO:0050679positive regulation of epithelial cell proliferation0.0134564208330796
GO:0055001muscle cell development0.0134564208330796
GO:0035051cardiac cell differentiation0.0134564208330796
GO:0009798axis specification0.0139237070595951
GO:0007492endoderm development0.0139237070595951
GO:0048518positive regulation of biological process0.0141257569973187
GO:0031032actomyosin structure organization and biogenesis0.0141257569973187
GO:0048628myoblast maturation0.0141257569973187
GO:0048627myoblast development0.0141257569973187
GO:0005178integrin binding0.0141257569973187
GO:0035137hindlimb morphogenesis0.0141257569973187
GO:0001708cell fate specification0.0141257569973187
GO:0050678regulation of epithelial cell proliferation0.0141257569973187
GO:0000082G1/S transition of mitotic cell cycle0.0141257569973187
GO:0046661male sex differentiation0.0154086494961967
GO:0042383sarcolemma0.0155089344533936
GO:0051146striated muscle cell differentiation0.01560345934
GO:0050673epithelial cell proliferation0.0162153497277896
GO:0008305integrin complex0.0173024896210547
GO:0045445myoblast differentiation0.0178371922030721
GO:0051325interphase0.0192962050831568
GO:0051329interphase of mitotic cell cycle0.0192962050831568
GO:0009953dorsal/ventral pattern formation0.0197428032994193
GO:0004702receptor signaling protein serine/threonine kinase activity0.020048920647292
GO:0048513organ development0.020048920647292
GO:0051216cartilage development0.020048920647292
GO:0007498mesoderm development0.020048920647292
GO:0032403protein complex binding0.020048920647292
GO:0019717synaptosome0.0208220025003276
GO:0042692muscle cell differentiation0.0225101491194736
GO:0007160cell-matrix adhesion0.0225101491194736
GO:0048741skeletal muscle fiber development0.0225101491194736
GO:0030324lung development0.0225101491194736
GO:0048747muscle fiber development0.0225101491194736
GO:0030323respiratory tube development0.0225101491194736
GO:0031589cell-substrate adhesion0.0225101491194736
GO:0043235receptor complex0.0225101491194736
GO:0019199transmembrane receptor protein kinase activity0.0225101491194736
GO:0007548sex differentiation0.0225101491194736
GO:0048731system development0.0225101491194736
GO:0048469cell maturation0.0225101491194736
GO:0035107appendage morphogenesis0.0225101491194736
GO:0035108limb morphogenesis0.0225101491194736
GO:0048869cellular developmental process0.0225101491194736
GO:0030154cell differentiation0.0225101491194736
GO:0060173limb development0.0225101491194736
GO:0048736appendage development0.0225101491194736
GO:0007178transmembrane receptor protein serine/threonine kinase signaling pathway0.0225101491194736
GO:0045596negative regulation of cell differentiation0.0234347923769146
GO:0005057receptor signaling protein activity0.0234347923769146
GO:0003006reproductive developmental process0.0234347923769146
GO:0007229integrin-mediated signaling pathway0.0240954568246319
GO:0021700developmental maturation0.0240954568246319
GO:0009952anterior/posterior pattern formation0.0244627432461561
GO:0007519skeletal muscle development0.0244627432461561
GO:0048856anatomical structure development0.0249770199198955
GO:0045165cell fate commitment0.0249770199198955
GO:0007398ectoderm development0.0249770199198955
GO:0051093negative regulation of developmental process0.0253828078295289
GO:0001701in utero embryonic development0.0286596186228907
GO:0014706striated muscle development0.0290078124494747
GO:0007275multicellular organismal development0.029292524320212
GO:0030145manganese ion binding0.0299091014344784
GO:0003002regionalization0.033650165201287
GO:0045595regulation of cell differentiation0.0344065819266945
GO:0030036actin cytoskeleton organization and biogenesis0.0344065819266945
GO:0030029actin filament-based process0.0358386395598984
GO:0007517muscle development0.0358386395598984
GO:0007166cell surface receptor linked signal transduction0.0358386395598984
GO:0001501skeletal development0.0383600521512519
GO:0035295tube development0.0423296095286837
GO:0022414reproductive process0.0428946476526525
GO:0004872receptor activity0.0435784814301501
GO:0032502developmental process0.0441059329296329
GO:0043009chordate embryonic development0.044165931537471
GO:0009792embryonic development ending in birth or egg hatching0.044165931537471
GO:0000278mitotic cell cycle0.044165931537471
GO:0007389pattern specification process0.0456444403706497
GO:0004871signal transducer activity0.0467989271816792
GO:0060089molecular transducer activity0.0467989271816792
GO:0050793regulation of developmental process0.0483932215224717
GO:0007167enzyme linked receptor protein signaling pathway0.0497670129224057
GO:0022403cell cycle phase0.0498889685485099
GO:0050794regulation of cellular process0.0498889685485099



Relative expression of the co-expression cluster over median <br>Analyst:




Enriched sample ontology terms on this co-expression cluster<b>Summary:</b>To summarize promoter activities (expression profile of a TSS region) across ~1000 samples, we performed enrichment analysis based on FANTOM5 Sample Ontology (FF ontology). The question here is “in which type of samples the promoter is more active”. To answer this question, we compared expressions (TPMs) in the samples associated with a sample ontology term and the rest of the samples by using the Mann-Whitney rank sum test. To summarize ontologies enriched in this co-expression cluster, we ran the same analysis on an averaged expression profile of all promoters that make up. <b>Analyst:</b> Hideya Kawaji <br><br>links to source dataset<br><br><br>uberon_data<br><br>

Uber Anatomy
Ontology termp-valuen
multi-cellular organism8.90e-07333


TFBS overrepresentation<b>Summary:</b>The values shown are the p-values for overrepresentation of the motif in this coexpression cluster. So a small p-value means a strong overrepresentation. <b>Analyst:</b> Michiel de Hoon <br><br>link to source data <br> Novel motifs <br>data <br><br> Jaspar motifs <br>data

Novel motifs




JASPAR motifs


Motifs-log10(p-value)
MA0003.11.87396
MA0004.10.801718
MA0006.11.46714
MA0007.10.784593
MA0009.11.27673
MA0014.12.60474
MA0017.10.635031
MA0019.11.08369
MA0024.11.23079
MA0025.11.51835
MA0027.12.9431
MA0028.10.61552
MA0029.11.20789
MA0030.11.21482
MA0031.11.17722
MA0038.10.963265
MA0040.11.28983
MA0041.10.714279
MA0042.10.69885
MA0043.11.3775
MA0046.11.31428
MA0048.10.932001
MA0050.10.845669
MA0051.10.973068
MA0052.11.29825
MA0055.10.190475
MA0056.10
MA0057.12.43475
MA0058.10.690848
MA0059.10.705317
MA0060.10.502699
MA0061.10.5406
MA0063.10
MA0066.10.951196
MA0067.11.63197
MA0068.10.343188
MA0069.11.29861
MA0070.11.28847
MA0071.10.844726
MA0072.11.2796
MA0073.10.25258
MA0074.10.911576
MA0076.10.657929
MA0077.11.2569
MA0078.11.0091
MA0081.10.732313
MA0083.11.37668
MA0084.11.96428
MA0087.11.33189
MA0088.11.40099
MA0089.10
MA0090.11.7994
MA0091.10.816659
MA0092.10.762845
MA0093.10.62555
MA0095.10
MA0098.10
MA0100.10.89873
MA0101.10.71579
MA0103.10.647985
MA0105.11.04599
MA0106.11.01755
MA0107.10.640607
MA0108.21.10817
MA0109.10
MA0111.10.778753
MA0113.10.986839
MA0114.10.537669
MA0115.11.38041
MA0116.10.602598
MA0117.12.98823
MA0119.10.716476
MA0122.11.36752
MA0124.11.57762
MA0125.11.5017
MA0130.10
MA0131.12.44622
MA0132.10
MA0133.10
MA0135.11.4152
MA0136.10.933582
MA0139.10.462282
MA0140.10.898603
MA0141.10.671467
MA0142.11.16183
MA0143.11.00467
MA0144.10.541532
MA0145.10.292366
MA0146.14.37098
MA0147.10.556853
MA0148.10.820161
MA0149.10.722227
MA0062.21.86813
MA0035.20.903829
MA0039.23.25387
MA0138.21.07027
MA0002.20.466067
MA0137.20.668025
MA0104.20.48458
MA0047.20.962424
MA0112.20.29236
MA0065.21.44804
MA0150.10.784464
MA0151.10
MA0152.10.962542
MA0153.11.43238
MA0154.10.35067
MA0155.10.312898
MA0156.10.656895
MA0157.11.12772
MA0158.10
MA0159.10.569393
MA0160.10.823568
MA0161.10
MA0162.17.41514
MA0163.10.927936
MA0164.10.933981
MA0080.20.64167
MA0018.20.944669
MA0099.21.06348
MA0079.27.3104
MA0102.22.01714
MA0258.10.520639
MA0259.10.543506
MA0442.10
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