Novel motif:44

name:	motif44_TGAAGST

Association to promoter expression in human samples<b>Summary:</b>Significance of the correlation with CAGE expression, human <br><b>Analyst:</b> Michiel de Hoon<br><br>link to source dataset <br>data

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Association to promoter expression in mouse samples <b>Summary:</b>Significance of the correlation with CAGE expression, mouse <br><b>Analyst:</b> Michiel de Hoon<br><br>link to source dataset <br>data

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GREAT analysis results for human <b>Summary:</b>Genomic Enrichment of Annotations Tool (GREAT, Nat Biotechnol. 2010 May;28(5):495-501) is used to identify, both in human and in mouse, the gene ontology terms of biological processes enriched given the predicted TFBSs, and evaluated the overlap in the top-500 gene ontology terms between human and mouse. For each novel motif, the P value for the overlap was then evaluated by calculating its relative rank with respect to this background distribution.<br>Analyst: Michiel de Hoon<br><br>link to source dataset <br>data

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GO ID	GO Term	p-value
GO:0045214	sarcomere organization	1.182871e-71
GO:0030240	skeletal muscle thin filament assembly	4.195586e-54
GO:0030239	myofibril assembly	6.191651e-51
GO:0030049	muscle filament sliding	4.096909e-50
GO:0070252	actin-mediated cell contraction	9.980659e-50
GO:0030048	actin filament-based movement	3.203203e-46
GO:0014866	skeletal myofibril assembly	1.520638e-44
GO:0031032	actomyosin structure organization	5.784375e-44
GO:0048739	cardiac muscle fiber development	1.202482e-42
GO:0006941	striated muscle contraction	9.029672e-38
GO:0048769	sarcomerogenesis	3.558475e-37
GO:0051592	response to calcium ion	1.315867e-35
GO:0032501	multicellular organismal process	2.251025e-35
GO:0055008	cardiac muscle tissue morphogenesis	3.015411e-35
GO:0010038	response to metal ion	5.014138e-35
GO:0010035	response to inorganic substance	1.983928e-33
GO:0055002	striated muscle cell development	9.619855e-33
GO:0007076	mitotic chromosome condensation	3.231179e-32
GO:0060415	muscle tissue morphogenesis	6.696556e-32
GO:0010927	cellular component assembly involved in morphogenesis	2.755351e-31
GO:0055003	cardiac myofibril assembly	7.018271e-31
GO:0048747	muscle fiber development	1.486776e-30
GO:0030241	skeletal muscle myosin thick filament assembly	1.922092e-30
GO:0055001	muscle cell development	3.390425e-30
GO:0002576	platelet degranulation	4.710522e-30
GO:0048644	muscle organ morphogenesis	6.785490e-30
GO:0042692	muscle cell differentiation	2.545612e-29
GO:0051146	striated muscle cell differentiation	5.535588e-29
GO:0030168	platelet activation	2.602803e-27
GO:0007015	actin filament organization	7.600207e-27
GO:0001775	cell activation	3.780504e-26
GO:0050896	response to stimulus	1.817180e-25
GO:0000070	mitotic sister chromatid segregation	2.321943e-25
GO:0000819	sister chromatid segregation	3.742560e-25
GO:0065008	regulation of biological quality	1.196179e-24
GO:0055013	cardiac muscle cell development	4.363673e-24
GO:0048738	cardiac muscle tissue development	8.359943e-24
GO:0007522	visceral muscle development	1.770756e-23
GO:0006928	cellular component movement	4.389078e-23
GO:0006936	muscle contraction	2.538761e-22
GO:0018149	peptide cross-linking	2.808911e-22
GO:0055007	cardiac muscle cell differentiation	5.794231e-22
GO:0016192	vesicle-mediated transport	6.707044e-22
GO:0042060	wound healing	7.450745e-22
GO:0050878	regulation of body fluid levels	2.525361e-21
GO:0061061	muscle structure development	2.615040e-21
GO:0032502	developmental process	5.335608e-21
GO:0003012	muscle system process	5.688239e-21
GO:0030261	chromosome condensation	8.123361e-21
GO:0007596	blood coagulation	8.942012e-21
GO:0007599	hemostasis	3.911885e-20
GO:0071844	cellular component assembly at cellular level	1.107287e-19
GO:0006887	exocytosis	1.414132e-19
GO:0051234	establishment of localization	1.785812e-19
GO:0030029	actin filament-based process	2.630520e-19
GO:0032989	cellular component morphogenesis	2.873211e-19
GO:0032940	secretion by cell	3.522899e-19
GO:0048513	organ development	4.541267e-19
GO:0009611	response to wounding	7.750443e-19
GO:0035051	cardiac cell differentiation	8.125599e-19
GO:0048731	system development	1.723337e-18
GO:0048856	anatomical structure development	1.793984e-18
GO:0007517	muscle organ development	2.984483e-18
GO:0006810	transport	4.578064e-18
GO:0030036	actin cytoskeleton organization	5.083294e-18
GO:0006950	response to stress	6.115623e-18
GO:0046903	secretion	6.266737e-18
GO:0007275	multicellular organismal development	7.850563e-18
GO:0007010	cytoskeleton organization	8.093228e-18
GO:0014706	striated muscle tissue development	1.039163e-17
GO:0060537	muscle tissue development	2.413123e-17
GO:0022607	cellular component assembly	2.866342e-17
GO:0014829	vascular smooth muscle contraction	3.623482e-17
GO:0002376	immune system process	5.462830e-17
GO:0051249	regulation of lymphocyte activation	7.515014e-17
GO:0042221	response to chemical stimulus	7.803833e-17
GO:0010951	negative regulation of endopeptidase activity	4.855386e-16
GO:0050863	regulation of T cell activation	6.223402e-16
GO:0046687	response to chromate	6.859861e-16
GO:0033986	response to methanol	6.859861e-16
GO:0044085	cellular component biogenesis	7.066679e-16
GO:0034330	cell junction organization	2.356977e-15
GO:0034329	cell junction assembly	3.552302e-15
GO:0002694	regulation of leukocyte activation	7.845031e-15
GO:0048869	cellular developmental process	1.000117e-14
GO:0051179	localization	1.686252e-14
GO:0010466	negative regulation of peptidase activity	1.699477e-14
GO:0030154	cell differentiation	5.906702e-14
GO:0034014	response to triglyceride	7.259357e-14
GO:0055009	atrial cardiac muscle tissue morphogenesis	7.519771e-14
GO:0044281	small molecule metabolic process	1.730004e-13
GO:0003008	system process	1.826111e-13
GO:0003007	heart morphogenesis	1.946909e-13
GO:0050870	positive regulation of T cell activation	2.264780e-13
GO:0002696	positive regulation of leukocyte activation	2.302870e-13
GO:0008217	regulation of blood pressure	2.650518e-13
GO:0051251	positive regulation of lymphocyte activation	2.788444e-13
GO:0021509	roof plate formation	4.723566e-13
GO:0031113	regulation of microtubule polymerization	5.312137e-13
GO:0043623	cellular protein complex assembly	5.486863e-13
GO:0051649	establishment of localization in cell	5.651054e-13
GO:0050865	regulation of cell activation	5.852145e-13
GO:0006953	acute-phase response	6.545414e-13
GO:0034332	adherens junction organization	7.141468e-13
GO:0051641	cellular localization	9.357784e-13
GO:0042310	vasoconstriction	1.045295e-12
GO:0016043	cellular component organization	1.254621e-12
GO:0072358	cardiovascular system development	1.416694e-12
GO:0051716	cellular response to stimulus	2.087102e-12
GO:0043462	regulation of ATPase activity	2.734427e-12
GO:0050867	positive regulation of cell activation	3.115146e-12
GO:0009888	tissue development	7.823102e-12
GO:0031424	keratinization	8.968906e-12
GO:0048685	negative regulation of collateral sprouting of intact axon in response to injury	2.207344e-11
GO:0043503	skeletal muscle fiber adaptation	2.223154e-11
GO:0007165	signal transduction	2.374911e-11
GO:0071840	cellular component organization or biogenesis	2.385773e-11
GO:0009156	ribonucleoside monophosphate biosynthetic process	3.155546e-11
GO:0048468	cell development	4.080104e-11
GO:0009653	anatomical structure morphogenesis	4.239984e-11
GO:0050900	leukocyte migration	5.083942e-11
GO:0023052	signaling	5.093491e-11
GO:0007186	G-protein coupled receptor protein signaling pathway	5.188069e-11
GO:0009161	ribonucleoside monophosphate metabolic process	5.439615e-11
GO:0009617	response to bacterium	6.108073e-11
GO:0048646	anatomical structure formation involved in morphogenesis	6.332806e-11
GO:0051346	negative regulation of hydrolase activity	6.769523e-11
GO:0051707	response to other organism	1.170352e-10
GO:0009607	response to biotic stimulus	1.386549e-10
GO:0007507	heart development	1.840181e-10
GO:0007059	chromosome segregation	2.181660e-10
GO:0008207	C21-steroid hormone metabolic process	4.332224e-10
GO:0007154	cell communication	4.421327e-10
GO:0071379	cellular response to prostaglandin stimulus	4.791066e-10
GO:0050892	intestinal absorption	7.619922e-10
GO:0007166	cell surface receptor linked signaling pathway	9.148791e-10
GO:0006642	triglyceride mobilization	1.179813e-9
GO:0045216	cell-cell junction organization	1.226859e-9
GO:0042159	lipoprotein catabolic process	1.536711e-9
GO:0009168	purine ribonucleoside monophosphate biosynthetic process	2.043622e-9
GO:0008202	steroid metabolic process	2.148646e-9
GO:0018350	protein esterification	2.231805e-9
GO:0044258	intestinal lipid catabolic process	2.231805e-9
GO:0007155	cell adhesion	2.536298e-9
GO:0050907	detection of chemical stimulus involved in sensory perception	2.706711e-9
GO:0031112	positive regulation of microtubule polymerization or depolymerization	2.750219e-9
GO:0009167	purine ribonucleoside monophosphate metabolic process	4.101531e-9
GO:0002027	regulation of heart rate	4.828808e-9
GO:0071842	cellular component organization at cellular level	5.182505e-9
GO:0032886	regulation of microtubule-based process	6.277485e-9
GO:0044282	small molecule catabolic process	6.824389e-9
GO:0009117	nucleotide metabolic process	7.147202e-9
GO:0030509	BMP signaling pathway	7.241381e-9
GO:0042632	cholesterol homeostasis	7.323156e-9
GO:0009605	response to external stimulus	7.971385e-9
GO:0050911	detection of chemical stimulus involved in sensory perception of smell	8.291873e-9
GO:0045621	positive regulation of lymphocyte differentiation	1.231377e-8
GO:0006898	receptor-mediated endocytosis	1.231455e-8
GO:0050670	regulation of lymphocyte proliferation	1.389485e-8
GO:0031295	T cell costimulation	1.411829e-8
GO:0006952	defense response	1.431482e-8
GO:0031110	regulation of microtubule polymerization or depolymerization	1.443064e-8
GO:0045582	positive regulation of T cell differentiation	1.467223e-8
GO:0002526	acute inflammatory response	1.523234e-8
GO:0009259	ribonucleotide metabolic process	1.533880e-8
GO:0050880	regulation of blood vessel size	1.638868e-8
GO:0060571	morphogenesis of an epithelial fold	1.659278e-8
GO:0002504	antigen processing and presentation of peptide or polysaccharide antigen via MHC class II	1.807158e-8
GO:0071841	cellular component organization or biogenesis at cellular level	1.846491e-8
GO:0006629	lipid metabolic process	1.979601e-8
GO:0007512	adult heart development	2.042885e-8
GO:0070663	regulation of leukocyte proliferation	2.069232e-8
GO:0006955	immune response	2.073457e-8
GO:0009191	ribonucleoside diphosphate catabolic process	2.330905e-8
GO:0035150	regulation of tube size	2.411376e-8
GO:0008015	blood circulation	2.620166e-8
GO:0003013	circulatory system process	2.806398e-8
GO:0002026	regulation of the force of heart contraction	2.835688e-8
GO:0010288	response to lead ion	2.878851e-8
GO:0055086	nucleobase-containing small molecule metabolic process	2.998263e-8
GO:0032944	regulation of mononuclear cell proliferation	3.158493e-8
GO:0052547	regulation of peptidase activity	3.320504e-8
GO:0048305	immunoglobulin secretion	3.481475e-8
GO:0007608	sensory perception of smell	3.552159e-8
GO:0009612	response to mechanical stimulus	3.633941e-8
GO:0030299	intestinal cholesterol absorption	3.876206e-8
GO:0000902	cell morphogenesis	4.701737e-8
GO:0046483	heterocycle metabolic process	5.111681e-8
GO:0045110	intermediate filament bundle assembly	5.219265e-8
GO:0007320	insemination	5.745600e-8
GO:0032924	activin receptor signaling pathway	5.893544e-8
GO:0006725	cellular aromatic compound metabolic process	6.405881e-8
GO:0019538	protein metabolic process	7.345191e-8
GO:0009124	nucleoside monophosphate biosynthetic process	7.481622e-8
GO:0045580	regulation of T cell differentiation	7.823933e-8
GO:0009181	purine ribonucleoside diphosphate catabolic process	9.392867e-8
GO:0007606	sensory perception of chemical stimulus	9.863658e-8
GO:0065007	biological regulation	9.948536e-8
GO:0006066	alcohol metabolic process	1.023954e-7
GO:0046314	phosphocreatine biosynthetic process	1.039207e-7
GO:0006323	DNA packaging	1.136171e-7
GO:0000904	cell morphogenesis involved in differentiation	1.268846e-7
GO:0070507	regulation of microtubule cytoskeleton organization	1.335374e-7
GO:0001692	histamine metabolic process	1.492778e-7
GO:0010715	regulation of extracellular matrix disassembly	1.635728e-7
GO:0042953	lipoprotein transport	1.673279e-7
GO:0044240	multicellular organismal lipid catabolic process	1.711709e-7
GO:0006457	protein folding	1.723233e-7
GO:0008211	glucocorticoid metabolic process	1.742792e-7
GO:0031116	positive regulation of microtubule polymerization	1.934074e-7
GO:0006600	creatine metabolic process	2.042531e-7
GO:0031115	negative regulation of microtubule polymerization	2.106375e-7
GO:0055088	lipid homeostasis	2.131887e-7
GO:0001694	histamine biosynthetic process	2.164366e-7
GO:0045575	basophil activation	2.164366e-7
GO:0044271	cellular nitrogen compound biosynthetic process	2.165817e-7
GO:0046709	IDP catabolic process	2.247873e-7
GO:0046032	ADP catabolic process	2.247873e-7
GO:0090082	positive regulation of heart induction by negative regulation of canonical Wnt receptor signaling pathway	2.653822e-7
GO:0009150	purine ribonucleotide metabolic process	2.789343e-7
GO:0050790	regulation of catalytic activity	3.030328e-7
GO:0071396	cellular response to lipid	3.055644e-7
GO:0002684	positive regulation of immune system process	3.241250e-7
GO:0034379	very-low-density lipoprotein particle assembly	3.312306e-7
GO:0006144	purine base metabolic process	3.327479e-7
GO:0006775	fat-soluble vitamin metabolic process	3.442802e-7
GO:0051336	regulation of hydrolase activity	3.854012e-7
GO:0009309	amine biosynthetic process	3.894918e-7
GO:0043086	negative regulation of catalytic activity	4.238840e-7
GO:0030888	regulation of B cell proliferation	4.418576e-7
GO:0009593	detection of chemical stimulus	4.688837e-7
GO:0001578	microtubule bundle formation	4.931556e-7
GO:0010040	response to iron(II) ion	5.337767e-7
GO:0007618	mating	5.404710e-7
GO:0048753	pigment granule organization	5.665025e-7
GO:0071243	cellular response to arsenic-containing substance	5.743127e-7
GO:0042396	phosphagen biosynthetic process	5.772405e-7
GO:0051250	negative regulation of lymphocyte activation	6.516364e-7
GO:0050776	regulation of immune response	7.896118e-7
GO:0019882	antigen processing and presentation	8.522136e-7
GO:0048545	response to steroid hormone stimulus	9.011679e-7
GO:0019433	triglyceride catabolic process	9.033148e-7
GO:0031111	negative regulation of microtubule polymerization or depolymerization	9.554065e-7
GO:0009169	purine ribonucleoside monophosphate catabolic process	9.965368e-7
GO:0051915	induction of synaptic plasticity by chemical substance	1.035820e-6
GO:0003127	detection of nodal flow	1.061282e-6
GO:0071103	DNA conformation change	1.068987e-6
GO:0003308	negative regulation of Wnt receptor signaling pathway involved in heart development	1.092649e-6
GO:0006163	purine nucleotide metabolic process	1.159915e-6
GO:0030317	sperm motility	1.177970e-6
GO:0002697	regulation of immune effector process	1.200869e-6
GO:0032496	response to lipopolysaccharide	1.202861e-6
GO:0042363	fat-soluble vitamin catabolic process	1.239934e-6
GO:2000514	regulation of CD4-positive, alpha-beta T cell activation	1.300120e-6
GO:0046503	glycerolipid catabolic process	1.332973e-6
GO:0046464	acylglycerol catabolic process	1.350858e-6
GO:0002090	regulation of receptor internalization	1.367012e-6
GO:0043370	regulation of CD4-positive, alpha-beta T cell differentiation	1.407575e-6
GO:0002237	response to molecule of bacterial origin	1.431994e-6
GO:0051704	multi-organism process	1.441376e-6
GO:0006824	cobalt ion transport	1.451248e-6
GO:0033137	negative regulation of peptidyl-serine phosphorylation	1.532138e-6
GO:0008544	epidermis development	1.534300e-6
GO:0040011	locomotion	1.542158e-6
GO:0006508	proteolysis	1.576434e-6
GO:0034369	plasma lipoprotein particle remodeling	1.725870e-6
GO:0009887	organ morphogenesis	1.732577e-6
GO:0006576	cellular biogenic amine metabolic process	1.800830e-6
GO:0009112	nucleobase metabolic process	1.906672e-6
GO:0045622	regulation of T-helper cell differentiation	1.930524e-6
GO:0061088	regulation of sequestering of zinc ion	1.980280e-6
GO:0010716	negative regulation of extracellular matrix disassembly	1.980280e-6
GO:0003198	epithelial to mesenchymal transition involved in endocardial cushion formation	2.105832e-6
GO:0042742	defense response to bacterium	2.119734e-6
GO:0016337	cell-cell adhesion	2.159360e-6
GO:0050869	negative regulation of B cell activation	2.191585e-6
GO:2000021	regulation of ion homeostasis	2.233560e-6
GO:0006547	histidine metabolic process	2.240943e-6
GO:0048878	chemical homeostasis	2.275927e-6
GO:0050671	positive regulation of lymphocyte proliferation	2.292401e-6
GO:0033693	neurofilament bundle assembly	2.536993e-6
GO:0006959	humoral immune response	2.667300e-6
GO:0051606	detection of stimulus	2.699876e-6
GO:0009310	amine catabolic process	2.726872e-6
GO:0050906	detection of stimulus involved in sensory perception	2.746258e-6
GO:0006811	ion transport	2.758959e-6
GO:0003209	cardiac atrium morphogenesis	2.767739e-6
GO:0009261	ribonucleotide catabolic process	2.770426e-6
GO:0044241	lipid digestion	2.806926e-6
GO:0010043	response to zinc ion	2.947911e-6
GO:0032438	melanosome organization	2.968992e-6
GO:0070863	positive regulation of protein exit from endoplasmic reticulum	3.045029e-6
GO:0016050	vesicle organization	3.049062e-6
GO:0015015	heparan sulfate proteoglycan biosynthetic process, enzymatic modification	3.068791e-6
GO:0071577	zinc ion transmembrane transport	3.072503e-6
GO:0042537	benzene-containing compound metabolic process	3.088253e-6
GO:0006548	histidine catabolic process	3.198658e-6
GO:0034754	cellular hormone metabolic process	3.258208e-6
GO:0030901	midbrain development	3.299497e-6
GO:0019896	axon transport of mitochondrion	3.322907e-6
GO:0014888	striated muscle adaptation	3.361546e-6
GO:0016049	cell growth	3.663196e-6
GO:0048683	regulation of collateral sprouting of intact axon in response to injury	3.728881e-6
GO:0048662	negative regulation of smooth muscle cell proliferation	3.756265e-6
GO:0042276	error-prone translesion synthesis	4.015428e-6
GO:0043501	skeletal muscle adaptation	4.042751e-6
GO:0046131	pyrimidine ribonucleoside metabolic process	4.215854e-6
GO:0048853	forebrain morphogenesis	4.382136e-6
GO:0044243	multicellular organismal catabolic process	4.382557e-6
GO:0072521	purine-containing compound metabolic process	4.492286e-6
GO:0006829	zinc ion transport	4.539079e-6
GO:0009154	purine ribonucleotide catabolic process	4.579871e-6
GO:0045923	positive regulation of fatty acid metabolic process	4.852910e-6
GO:0034383	low-density lipoprotein particle clearance	4.869851e-6
GO:0031175	neuron projection development	5.012625e-6
GO:0032946	positive regulation of mononuclear cell proliferation	5.091126e-6
GO:0090081	regulation of heart induction by regulation of canonical Wnt receptor signaling pathway	5.174219e-6
GO:0044106	cellular amine metabolic process	5.358731e-6
GO:0030889	negative regulation of B cell proliferation	5.650923e-6
GO:0048729	tissue morphogenesis	5.668187e-6
GO:0048671	negative regulation of collateral sprouting	5.760910e-6
GO:0019932	second-messenger-mediated signaling	5.780212e-6
GO:0031581	hemidesmosome assembly	5.978960e-6
GO:0010886	positive regulation of cholesterol storage	5.988029e-6
GO:0042129	regulation of T cell proliferation	6.980114e-6
GO:0002502	peptide antigen assembly with MHC class I protein complex	6.996146e-6
GO:0015918	sterol transport	7.030801e-6
GO:0003230	cardiac atrium development	7.107061e-6
GO:0003307	regulation of Wnt receptor signaling pathway involved in heart development	7.303093e-6
GO:0034377	plasma lipoprotein particle assembly	7.437878e-6
GO:0002637	regulation of immunoglobulin production	7.702822e-6
GO:0051023	regulation of immunoglobulin secretion	7.727196e-6
GO:0021527	spinal cord association neuron differentiation	7.727196e-6
GO:0050801	ion homeostasis	8.183372e-6
GO:0008652	cellular amino acid biosynthetic process	8.350138e-6
GO:0043372	positive regulation of CD4-positive, alpha-beta T cell differentiation	8.528151e-6
GO:0034723	DNA replication-dependent nucleosome organization	8.538927e-6
GO:0002682	regulation of immune system process	8.570978e-6
GO:0045619	regulation of lymphocyte differentiation	8.680881e-6
GO:0045624	positive regulation of T-helper cell differentiation	9.284078e-6
GO:0046700	heterocycle catabolic process	9.451142e-6
GO:0002695	negative regulation of leukocyte activation	9.667723e-6
GO:0019800	peptide cross-linking via chondroitin 4-sulfate glycosaminoglycan	9.714135e-6
GO:0043627	response to estrogen stimulus	9.796713e-6
GO:0018904	organic ether metabolic process	9.861837e-6
GO:0055069	zinc ion homeostasis	9.981460e-6
GO:0070271	protein complex biogenesis	1.012565e-5
GO:0048870	cell motility	1.016376e-5
GO:0030301	cholesterol transport	1.078696e-5
GO:0048245	eosinophil chemotaxis	1.146820e-5
GO:0031623	receptor internalization	1.157375e-5
GO:0009743	response to carbohydrate stimulus	1.160831e-5
GO:0008089	anterograde axon cargo transport	1.181412e-5
GO:0003018	vascular process in circulatory system	1.231849e-5
GO:0034776	response to histamine	1.236778e-5
GO:0006029	proteoglycan metabolic process	1.262995e-5
GO:0071466	cellular response to xenobiotic stimulus	1.283700e-5
GO:0055082	cellular chemical homeostasis	1.362355e-5
GO:0002699	positive regulation of immune effector process	1.386748e-5
GO:0044242	cellular lipid catabolic process	1.390411e-5
GO:0042592	homeostatic process	1.415112e-5
GO:0006461	protein complex assembly	1.435869e-5
GO:0014012	peripheral nervous system axon regeneration	1.454296e-5
GO:0070665	positive regulation of leukocyte proliferation	1.475080e-5
GO:0010970	microtubule-based transport	1.478033e-5
GO:0031579	membrane raft organization	1.500403e-5
GO:0034622	cellular macromolecular complex assembly	1.618849e-5
GO:0043516	regulation of DNA damage response, signal transduction by p53 class mediator	1.691635e-5
GO:0015889	cobalamin transport	1.719332e-5
GO:0007585	respiratory gaseous exchange	1.723150e-5
GO:0009052	pentose-phosphate shunt, non-oxidative branch	1.814873e-5
GO:0050868	negative regulation of T cell activation	1.935787e-5
GO:0009308	amine metabolic process	1.964522e-5
GO:0044092	negative regulation of molecular function	2.088029e-5
GO:0051258	protein polymerization	2.256076e-5
GO:0048676	axon extension involved in development	2.334160e-5
GO:0006897	endocytosis	2.335485e-5
GO:0034374	low-density lipoprotein particle remodeling	2.343387e-5
GO:0006584	catecholamine metabolic process	2.345802e-5
GO:0065009	regulation of molecular function	2.459174e-5
GO:0009987	cellular process	2.509017e-5
GO:0030216	keratinocyte differentiation	2.530646e-5
GO:0042157	lipoprotein metabolic process	2.623104e-5
GO:0006196	AMP catabolic process	2.655491e-5
GO:0046164	alcohol catabolic process	2.678695e-5
GO:0031214	biomineral tissue development	2.689485e-5
GO:0019725	cellular homeostasis	2.696606e-5
GO:0007044	cell-substrate junction assembly	2.710951e-5
GO:0050864	regulation of B cell activation	2.763156e-5
GO:0033059	cellular pigmentation	2.839132e-5
GO:0070741	response to interleukin-6	2.853767e-5
GO:0042127	regulation of cell proliferation	2.860921e-5
GO:0030201	heparan sulfate proteoglycan metabolic process	2.863380e-5
GO:0009410	response to xenobiotic stimulus	2.918867e-5
GO:0060638	mesenchymal-epithelial cell signaling	2.931733e-5
GO:0046321	positive regulation of fatty acid oxidation	3.040248e-5
GO:0060665	regulation of branching involved in salivary gland morphogenesis by mesenchymal-epithelial signaling	3.088243e-5
GO:0045104	intermediate filament cytoskeleton organization	3.125258e-5
GO:0009712	catechol-containing compound metabolic process	3.160852e-5
GO:0060539	diaphragm development	3.356162e-5
GO:0019883	antigen processing and presentation of endogenous antigen	3.356162e-5
GO:0051953	negative regulation of amine transport	3.378822e-5
GO:0006873	cellular ion homeostasis	3.606904e-5
GO:0009165	nucleotide biosynthetic process	3.670857e-5
GO:0006447	regulation of translational initiation by iron	3.698783e-5
GO:0048012	hepatocyte growth factor receptor signaling pathway	3.712809e-5
GO:0031630	regulation of synaptic vesicle fusion to presynaptic membrane	3.952365e-5
GO:0048790	maintenance of presynaptic active zone structure	3.952365e-5
GO:0016042	lipid catabolic process	3.963438e-5
GO:0006213	pyrimidine nucleoside metabolic process	3.986803e-5
GO:0019752	carboxylic acid metabolic process	4.030446e-5
GO:0042445	hormone metabolic process	4.187394e-5
GO:0006116	NADH oxidation	4.253406e-5
GO:0045423	regulation of granulocyte macrophage colony-stimulating factor biosynthetic process	4.273314e-5
GO:0018958	phenol-containing compound metabolic process	4.467445e-5
GO:0006458	'de novo' protein folding	4.617118e-5
GO:0006996	organelle organization	4.624786e-5
GO:0007409	axonogenesis	4.669085e-5
GO:0045109	intermediate filament organization	4.699119e-5
GO:0046649	lymphocyte activation	4.761854e-5
GO:0072523	purine-containing compound catabolic process	4.788290e-5
GO:0048660	regulation of smooth muscle cell proliferation	4.812336e-5
GO:0046634	regulation of alpha-beta T cell activation	4.971722e-5
GO:0042524	negative regulation of tyrosine phosphorylation of Stat5 protein	5.005208e-5
GO:0044270	cellular nitrogen compound catabolic process	5.108818e-5
GO:0090381	regulation of heart induction	5.151498e-5
GO:0048858	cell projection morphogenesis	5.308798e-5
GO:0001964	startle response	5.476417e-5
GO:0046395	carboxylic acid catabolic process	5.670729e-5
GO:0009063	cellular amino acid catabolic process	5.760460e-5
GO:0042325	regulation of phosphorylation	5.855879e-5
GO:0045348	positive regulation of MHC class II biosynthetic process	5.950132e-5
GO:0015698	inorganic anion transport	5.962782e-5
GO:0050789	regulation of biological process	6.056027e-5
GO:0042832	defense response to protozoan	6.143729e-5
GO:0034654	nucleobase-containing compound biosynthetic process	6.190443e-5
GO:0008285	negative regulation of cell proliferation	6.241237e-5
GO:0019220	regulation of phosphate metabolic process	6.286957e-5
GO:0010155	regulation of proton transport	6.289358e-5
GO:0006207	'de novo' pyrimidine base biosynthetic process	6.317847e-5
GO:0001932	regulation of protein phosphorylation	6.318589e-5
GO:0046635	positive regulation of alpha-beta T cell activation	6.331971e-5
GO:0048666	neuron development	6.430682e-5
GO:0032844	regulation of homeostatic process	6.435209e-5
GO:0031099	regeneration	6.453758e-5
GO:0006957	complement activation, alternative pathway	6.458626e-5
GO:0090181	regulation of cholesterol metabolic process	6.663952e-5
GO:0019217	regulation of fatty acid metabolic process	6.835961e-5
GO:0048854	brain morphogenesis	6.909818e-5
GO:0009100	glycoprotein metabolic process	7.046074e-5
GO:0048667	cell morphogenesis involved in neuron differentiation	7.070762e-5
GO:0002819	regulation of adaptive immune response	7.075177e-5
GO:0006869	lipid transport	7.087093e-5
GO:0006335	DNA replication-dependent nucleosome assembly	7.155703e-5
GO:0060070	canonical Wnt receptor signaling pathway	7.343429e-5
GO:0060134	prepulse inhibition	7.356681e-5
GO:0032990	cell part morphogenesis	7.375297e-5
GO:0030030	cell projection organization	7.698020e-5
GO:0052548	regulation of endopeptidase activity	7.705719e-5
GO:0044356	clearance of foreign intracellular DNA by conversion of DNA cytidine to uridine	7.709911e-5
GO:0015012	heparan sulfate proteoglycan biosynthetic process	7.780275e-5
GO:0090066	regulation of anatomical structure size	7.810739e-5
GO:0042180	cellular ketone metabolic process	7.854604e-5
GO:0042102	positive regulation of T cell proliferation	7.860171e-5
GO:0009791	post-embryonic development	7.879451e-5
GO:0007156	homophilic cell adhesion	7.972983e-5
GO:0010977	negative regulation of neuron projection development	7.974271e-5
GO:0035358	regulation of peroxisome proliferator activated receptor signaling pathway	8.009553e-5
GO:0032355	response to estradiol stimulus	8.169189e-5
GO:0050866	negative regulation of cell activation	8.224320e-5
GO:0045321	leukocyte activation	8.365605e-5
GO:0046637	regulation of alpha-beta T cell differentiation	8.665930e-5
GO:0045019	negative regulation of nitric oxide biosynthetic process	8.783699e-5
GO:0009260	ribonucleotide biosynthetic process	8.934091e-5
GO:0034694	response to prostaglandin stimulus	8.961460e-5
GO:0048812	neuron projection morphogenesis	9.101115e-5
GO:0050778	positive regulation of immune response	9.223561e-5
GO:0007259	JAK-STAT cascade	9.321442e-5
GO:0034655	nucleobase-containing compound catabolic process	9.356439e-5
GO:0044283	small molecule biosynthetic process	9.507804e-5
GO:0045425	positive regulation of granulocyte macrophage colony-stimulating factor biosynthetic process	9.509391e-5
GO:0050709	negative regulation of protein secretion	9.565995e-5
GO:0047497	mitochondrion transport along microtubule	9.687613e-5
GO:0006805	xenobiotic metabolic process	9.760101e-5
GO:0050852	T cell receptor signaling pathway	9.789202e-5
GO:0030953	astral microtubule organization	1.006090e-4
GO:2000820	negative regulation of transcription from RNA polymerase II promoter involved in smooth muscle cell differentiation	1.018591e-4
GO:0031399	regulation of protein modification process	1.019527e-4
GO:0009056	catabolic process	1.045626e-4
GO:0003203	endocardial cushion morphogenesis	1.049224e-4
GO:0016477	cell migration	1.053425e-4
GO:0009913	epidermal cell differentiation	1.054391e-4
GO:0042483	negative regulation of odontogenesis	1.069067e-4
GO:0016246	RNA interference	1.069067e-4
GO:0035360	positive regulation of peroxisome proliferator activated receptor signaling pathway	1.075057e-4
GO:0044248	cellular catabolic process	1.106279e-4
GO:0002683	negative regulation of immune system process	1.119972e-4
GO:0007354	zygotic determination of anterior/posterior axis, embryo	1.136007e-4
GO:0046496	nicotinamide nucleotide metabolic process	1.149828e-4
GO:0042758	long-chain fatty acid catabolic process	1.163959e-4

GREAT analysis results for mouseGenomic Enrichment of Annotations Tool (GREAT, Nat Biotechnol. 2010 May;28(5):495-501) is used to identify, both in human and in mouse, the gene ontology terms of biological processes enriched given the predicted TFBSs, and evaluated the overlap in the top-500 gene ontology terms between human and mouse. For each novel motif, the P value for the overlap was then evaluated by calculating its relative rank with respect to this background distribution.<br>Analyst: Michiel de Hoon <br><br>link to source dataset <br>data

---

GO ID	GO Term	p-value
GO:0006952	defense response	2.872061e-21
GO:0050896	response to stimulus	3.411238e-21
GO:0042221	response to chemical stimulus	5.401943e-17
GO:0003012	muscle system process	4.129777e-15
GO:0010035	response to inorganic substance	4.196731e-15
GO:0008202	steroid metabolic process	4.096180e-14
GO:0055114	oxidation-reduction process	5.876185e-14
GO:0007512	adult heart development	7.017106e-14
GO:0050863	regulation of T cell activation	3.309280e-13
GO:0006936	muscle contraction	3.390505e-13
GO:0006950	response to stress	5.065262e-13
GO:0051249	regulation of lymphocyte activation	9.351243e-13
GO:0050870	positive regulation of T cell activation	1.771400e-12
GO:0051704	multi-organism process	2.103048e-12
GO:0006629	lipid metabolic process	4.611151e-12
GO:0050867	positive regulation of cell activation	9.730386e-12
GO:0002694	regulation of leukocyte activation	1.570509e-11
GO:0050865	regulation of cell activation	1.766020e-11
GO:0010033	response to organic substance	1.846643e-11
GO:0002696	positive regulation of leukocyte activation	3.753842e-11
GO:0009607	response to biotic stimulus	6.520185e-11
GO:0043056	forward locomotion	1.199314e-10
GO:0002684	positive regulation of immune system process	1.630675e-10
GO:0016125	sterol metabolic process	1.859426e-10
GO:0043434	response to peptide hormone stimulus	2.639800e-10
GO:0051707	response to other organism	2.658711e-10
GO:0046464	acylglycerol catabolic process	3.018532e-10
GO:0009725	response to hormone stimulus	4.397127e-10
GO:0034369	plasma lipoprotein particle remodeling	6.089500e-10
GO:0051251	positive regulation of lymphocyte activation	7.449254e-10
GO:0042742	defense response to bacterium	7.708096e-10
GO:0008203	cholesterol metabolic process	1.380030e-9
GO:0044255	cellular lipid metabolic process	1.409595e-9
GO:0033058	directional locomotion	2.870317e-9
GO:0006278	RNA-dependent DNA replication	3.251837e-9
GO:0046503	glycerolipid catabolic process	3.471468e-9
GO:0002376	immune system process	4.314723e-9
GO:0006955	immune response	4.854363e-9
GO:0050670	regulation of lymphocyte proliferation	5.147050e-9
GO:0010873	positive regulation of cholesterol esterification	6.059455e-9
GO:0031341	regulation of cell killing	6.502499e-9
GO:0006066	alcohol metabolic process	8.463896e-9
GO:0032101	regulation of response to external stimulus	8.636001e-9
GO:0070663	regulation of leukocyte proliferation	8.638410e-9
GO:0002682	regulation of immune system process	9.412806e-9
GO:0032944	regulation of mononuclear cell proliferation	9.464120e-9
GO:0010038	response to metal ion	1.131302e-8
GO:0009617	response to bacterium	1.309904e-8
GO:0016042	lipid catabolic process	1.485850e-8
GO:0042129	regulation of T cell proliferation	1.758007e-8
GO:0001910	regulation of leukocyte mediated cytotoxicity	1.944963e-8
GO:0031347	regulation of defense response	2.933404e-8
GO:0051716	cellular response to stimulus	3.097122e-8
GO:0002891	positive regulation of immunoglobulin mediated immune response	3.529359e-8
GO:0060052	neurofilament cytoskeleton organization	3.601014e-8
GO:0032501	multicellular organismal process	3.966204e-8
GO:0006953	acute-phase response	4.219883e-8
GO:0044242	cellular lipid catabolic process	4.252859e-8
GO:0006941	striated muscle contraction	4.460392e-8
GO:0009719	response to endogenous stimulus	6.648532e-8
GO:0010872	regulation of cholesterol esterification	7.522188e-8
GO:0033687	osteoblast proliferation	7.869269e-8
GO:0051346	negative regulation of hydrolase activity	8.246991e-8
GO:0002227	innate immune response in mucosa	8.432834e-8
GO:0071827	plasma lipoprotein particle organization	8.792418e-8
GO:0055090	acylglycerol homeostasis	8.925492e-8
GO:0002706	regulation of lymphocyte mediated immunity	9.496292e-8
GO:0019218	regulation of steroid metabolic process	1.059840e-7
GO:0033275	actin-myosin filament sliding	1.116609e-7
GO:0008588	release of cytoplasmic sequestered NF-kappaB	1.324793e-7
GO:0071396	cellular response to lipid	1.397267e-7
GO:0043648	dicarboxylic acid metabolic process	1.406927e-7
GO:0065008	regulation of biological quality	1.664837e-7
GO:0002707	negative regulation of lymphocyte mediated immunity	1.867730e-7
GO:0030240	skeletal muscle thin filament assembly	1.944342e-7
GO:0006082	organic acid metabolic process	1.962659e-7
GO:0019433	triglyceride catabolic process	2.012786e-7
GO:0045103	intermediate filament-based process	2.174078e-7
GO:0034374	low-density lipoprotein particle remodeling	2.493114e-7
GO:0050930	induction of positive chemotaxis	2.854668e-7
GO:0044281	small molecule metabolic process	2.859051e-7
GO:0031295	T cell costimulation	3.053732e-7
GO:0070252	actin-mediated cell contraction	3.063864e-7
GO:0060754	positive regulation of mast cell chemotaxis	3.136801e-7
GO:0019285	glycine betaine biosynthetic process from choline	3.319573e-7
GO:0045104	intermediate filament cytoskeleton organization	3.745304e-7
GO:0002708	positive regulation of lymphocyte mediated immunity	4.007213e-7
GO:0002027	regulation of heart rate	4.891257e-7
GO:0014866	skeletal myofibril assembly	5.627796e-7
GO:0018904	organic ether metabolic process	6.823722e-7
GO:0006982	response to lipid hydroperoxide	7.276128e-7
GO:0010466	negative regulation of peptidase activity	7.437748e-7
GO:0001911	negative regulation of leukocyte mediated cytotoxicity	7.882193e-7
GO:0097006	regulation of plasma lipoprotein particle levels	7.975880e-7
GO:0006890	retrograde vesicle-mediated transport, Golgi to ER	7.995956e-7
GO:0045940	positive regulation of steroid metabolic process	8.080121e-7
GO:0032870	cellular response to hormone stimulus	8.264942e-7
GO:0010927	cellular component assembly involved in morphogenesis	8.634652e-7
GO:0040018	positive regulation of multicellular organism growth	8.655538e-7
GO:0045621	positive regulation of lymphocyte differentiation	9.235397e-7
GO:0031342	negative regulation of cell killing	9.468510e-7
GO:0009743	response to carbohydrate stimulus	9.494175e-7
GO:0043279	response to alkaloid	9.560803e-7
GO:0000305	response to oxygen radical	1.004887e-6
GO:0050766	positive regulation of phagocytosis	1.099025e-6
GO:0019752	carboxylic acid metabolic process	1.153961e-6
GO:0042269	regulation of natural killer cell mediated cytotoxicity	1.163615e-6
GO:0001878	response to yeast	1.169757e-6
GO:0061179	negative regulation of insulin secretion involved in cellular response to glucose stimulus	1.209936e-6
GO:0006820	anion transport	1.212686e-6
GO:0009611	response to wounding	1.213859e-6
GO:0042180	cellular ketone metabolic process	1.234172e-6
GO:0010902	positive regulation of very-low-density lipoprotein particle remodeling	1.291212e-6
GO:0009605	response to external stimulus	1.306613e-6
GO:0002683	negative regulation of immune system process	1.326678e-6
GO:0060695	negative regulation of cholesterol transporter activity	1.367275e-6
GO:0015759	beta-glucoside transport	1.367275e-6
GO:0043462	regulation of ATPase activity	1.408324e-6
GO:0007522	visceral muscle development	1.409690e-6
GO:0030239	myofibril assembly	1.474927e-6
GO:0009056	catabolic process	1.724101e-6
GO:0042743	hydrogen peroxide metabolic process	1.821759e-6
GO:0003008	system process	1.854291e-6
GO:0042439	ethanolamine-containing compound metabolic process	1.952504e-6
GO:0031343	positive regulation of cell killing	2.077419e-6
GO:0045658	regulation of neutrophil differentiation	2.221742e-6
GO:0042946	glucoside transport	2.576669e-6
GO:0001920	negative regulation of receptor recycling	2.576669e-6
GO:0045087	innate immune response	2.592250e-6
GO:0042270	protection from natural killer cell mediated cytotoxicity	2.650946e-6
GO:0000303	response to superoxide	2.672721e-6
GO:0071375	cellular response to peptide hormone stimulus	2.731220e-6
GO:0019430	removal of superoxide radicals	3.068170e-6
GO:0070887	cellular response to chemical stimulus	3.169049e-6
GO:0010901	regulation of very-low-density lipoprotein particle remodeling	3.659589e-6
GO:0006694	steroid biosynthetic process	3.751238e-6
GO:0072593	reactive oxygen species metabolic process	4.239077e-6
GO:0042102	positive regulation of T cell proliferation	4.557628e-6
GO:0030301	cholesterol transport	4.731692e-6
GO:0050672	negative regulation of lymphocyte proliferation	4.945176e-6
GO:0000302	response to reactive oxygen species	4.959085e-6
GO:0034435	cholesterol esterification	5.097483e-6
GO:0002526	acute inflammatory response	5.113353e-6
GO:0032536	regulation of cell projection size	5.211881e-6
GO:0045582	positive regulation of T cell differentiation	5.344842e-6
GO:0002703	regulation of leukocyte mediated immunity	5.646733e-6
GO:0070664	negative regulation of leukocyte proliferation	5.712076e-6
GO:0006801	superoxide metabolic process	5.795923e-6
GO:0031032	actomyosin structure organization	5.887691e-6
GO:0001912	positive regulation of leukocyte mediated cytotoxicity	6.224845e-6
GO:0051241	negative regulation of multicellular organismal process	6.525570e-6
GO:0080134	regulation of response to stress	6.709768e-6
GO:0019216	regulation of lipid metabolic process	6.860460e-6
GO:0032869	cellular response to insulin stimulus	6.948986e-6
GO:0050854	regulation of antigen receptor-mediated signaling pathway	7.205432e-6
GO:0051240	positive regulation of multicellular organismal process	7.549344e-6
GO:0031099	regeneration	7.692773e-6
GO:0050727	regulation of inflammatory response	7.781514e-6
GO:0008610	lipid biosynthetic process	8.090971e-6
GO:0035634	response to stilbenoid	8.506404e-6
GO:0043903	regulation of symbiosis, encompassing mutualism through parasitism	8.556522e-6
GO:0002920	regulation of humoral immune response	8.648345e-6
GO:0007154	cell communication	9.311741e-6
GO:0014070	response to organic cyclic compound	9.535711e-6
GO:0045619	regulation of lymphocyte differentiation	9.977963e-6
GO:0046967	cytosol to ER transport	1.022974e-5
GO:0019060	intracellular transport of viral proteins in host cell	1.022974e-5
GO:2000275	regulation of oxidative phosphorylation uncoupler activity	1.059347e-5
GO:0050746	regulation of lipoprotein metabolic process	1.090066e-5
GO:0002922	positive regulation of humoral immune response	1.172331e-5
GO:0034442	regulation of lipoprotein oxidation	1.183311e-5
GO:0055003	cardiac myofibril assembly	1.203717e-5
GO:0050907	detection of chemical stimulus involved in sensory perception	1.208375e-5
GO:0006816	calcium ion transport	1.258846e-5
GO:0048009	insulin-like growth factor receptor signaling pathway	1.259574e-5
GO:0048545	response to steroid hormone stimulus	1.321872e-5
GO:0071495	cellular response to endogenous stimulus	1.324889e-5
GO:0001970	positive regulation of activation of membrane attack complex	1.326188e-5
GO:0002819	regulation of adaptive immune response	1.352723e-5
GO:0045214	sarcomere organization	1.352731e-5
GO:0034445	negative regulation of plasma lipoprotein particle oxidation	1.390060e-5
GO:0009566	fertilization	1.435589e-5
GO:0023052	signaling	1.490203e-5
GO:0043086	negative regulation of catalytic activity	1.506150e-5
GO:0006639	acylglycerol metabolic process	1.532688e-5
GO:0050764	regulation of phagocytosis	1.546359e-5
GO:0045671	negative regulation of osteoclast differentiation	1.666942e-5
GO:0032656	regulation of interleukin-13 production	1.715680e-5
GO:0002820	negative regulation of adaptive immune response	1.777344e-5
GO:0009052	pentose-phosphate shunt, non-oxidative branch	1.796931e-5
GO:0060716	labyrinthine layer blood vessel development	1.825189e-5
GO:0045580	regulation of T cell differentiation	1.849210e-5
GO:0072511	divalent inorganic cation transport	1.859444e-5
GO:0045109	intermediate filament organization	1.871820e-5
GO:0046340	diacylglycerol catabolic process	1.879617e-5
GO:0040008	regulation of growth	1.938129e-5
GO:0007600	sensory perception	1.969050e-5
GO:0006979	response to oxidative stress	1.981538e-5
GO:0045927	positive regulation of growth	2.106787e-5
GO:0032868	response to insulin stimulus	2.150060e-5
GO:0010269	response to selenium ion	2.165651e-5
GO:0006706	steroid catabolic process	2.181606e-5
GO:0033194	response to hydroperoxide	2.191702e-5
GO:0014834	satellite cell maintenance involved in skeletal muscle regeneration	2.204065e-5
GO:0031133	regulation of axon diameter	2.254589e-5
GO:0032696	negative regulation of interleukin-13 production	2.346504e-5
GO:0010954	positive regulation of protein processing	2.387845e-5
GO:0006638	neutral lipid metabolic process	2.714384e-5
GO:0051250	negative regulation of lymphocyte activation	2.720543e-5
GO:0050671	positive regulation of lymphocyte proliferation	3.205143e-5
GO:0001887	selenium compound metabolic process	3.217100e-5
GO:0046890	regulation of lipid biosynthetic process	3.345315e-5
GO:0051138	positive regulation of NK T cell differentiation	3.437758e-5
GO:0001798	positive regulation of type IIa hypersensitivity	3.437758e-5
GO:0018894	dibenzo-p-dioxin metabolic process	3.437758e-5
GO:0050776	regulation of immune response	3.500959e-5
GO:0006968	cellular defense response	3.635414e-5
GO:0031953	negative regulation of protein autophosphorylation	3.672542e-5
GO:0070838	divalent metal ion transport	3.751164e-5
GO:0030049	muscle filament sliding	3.894694e-5
GO:0002385	mucosal immune response	3.897248e-5
GO:0006014	D-ribose metabolic process	3.975490e-5
GO:0002251	organ or tissue specific immune response	3.975490e-5
GO:0060056	mammary gland involution	4.068184e-5
GO:0002823	negative regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains	4.542420e-5
GO:0070665	positive regulation of leukocyte proliferation	4.554524e-5
GO:0008299	isoprenoid biosynthetic process	4.704681e-5
GO:0042632	cholesterol homeostasis	4.788272e-5
GO:0051239	regulation of multicellular organismal process	4.793375e-5
GO:0006811	ion transport	4.883440e-5
GO:0044243	multicellular organismal catabolic process	4.904467e-5
GO:0017144	drug metabolic process	4.925497e-5
GO:0045751	negative regulation of Toll signaling pathway	4.936350e-5
GO:0032462	regulation of protein homooligomerization	5.016110e-5
GO:0030300	regulation of intestinal cholesterol absorption	5.034161e-5
GO:2000277	positive regulation of oxidative phosphorylation uncoupler activity	5.154706e-5
GO:0032946	positive regulation of mononuclear cell proliferation	5.311726e-5
GO:0014904	myotube cell development	5.329764e-5
GO:0034383	low-density lipoprotein particle clearance	5.707689e-5
GO:0060765	regulation of androgen receptor signaling pathway	5.971241e-5
GO:0050906	detection of stimulus involved in sensory perception	6.070046e-5
GO:0014012	peripheral nervous system axon regeneration	6.087356e-5
GO:0045409	negative regulation of interleukin-6 biosynthetic process	6.154513e-5
GO:0009991	response to extracellular stimulus	6.220401e-5
GO:0001969	regulation of activation of membrane attack complex	7.098644e-5
GO:0043603	cellular amide metabolic process	7.271965e-5
GO:0032094	response to food	7.273276e-5
GO:0015698	inorganic anion transport	7.281276e-5
GO:0048583	regulation of response to stimulus	7.499437e-5
GO:0034381	plasma lipoprotein particle clearance	7.692375e-5
GO:0002889	regulation of immunoglobulin mediated immune response	7.773755e-5
GO:0045660	positive regulation of neutrophil differentiation	7.879549e-5
GO:0042098	T cell proliferation	7.901653e-5
GO:0030321	transepithelial chloride transport	8.185849e-5
GO:0060401	cytosolic calcium ion transport	8.270008e-5
GO:0030001	metal ion transport	8.670533e-5
GO:0034141	positive regulation of toll-like receptor 3 signaling pathway	8.740227e-5
GO:0030048	actin filament-based movement	8.783400e-5
GO:0006662	glycerol ether metabolic process	8.819563e-5
GO:0034284	response to monosaccharide stimulus	9.396448e-5
GO:0032663	regulation of interleukin-2 production	9.613746e-5
GO:0044130	negative regulation of growth of symbiont in host	9.654821e-5
GO:0006578	betaine biosynthetic process	1.007985e-4
GO:0052547	regulation of peptidase activity	1.021049e-4
GO:0007608	sensory perception of smell	1.061622e-4
GO:0044248	cellular catabolic process	1.073950e-4
GO:0051146	striated muscle cell differentiation	1.106454e-4
GO:0032689	negative regulation of interferon-gamma production	1.166488e-4
GO:0051592	response to calcium ion	1.167208e-4
GO:0043503	skeletal muscle fiber adaptation	1.178266e-4
GO:0050769	positive regulation of neurogenesis	1.218316e-4
GO:0045088	regulation of innate immune response	1.259893e-4
GO:0046006	regulation of activated T cell proliferation	1.265597e-4
GO:0070373	negative regulation of ERK1 and ERK2 cascade	1.313707e-4
GO:0044057	regulation of system process	1.323412e-4
GO:0002822	regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains	1.336569e-4
GO:0045953	negative regulation of natural killer cell mediated cytotoxicity	1.337217e-4
GO:0007165	signal transduction	1.343572e-4
GO:0033993	response to lipid	1.395163e-4
GO:0032673	regulation of interleukin-4 production	1.395843e-4
GO:0042104	positive regulation of activated T cell proliferation	1.418154e-4
GO:0006732	coenzyme metabolic process	1.425991e-4
GO:0032459	regulation of protein oligomerization	1.435778e-4
GO:0001560	regulation of cell growth by extracellular stimulus	1.465294e-4
GO:0048739	cardiac muscle fiber development	1.481916e-4
GO:0033344	cholesterol efflux	1.491842e-4
GO:0048304	positive regulation of isotype switching to IgG isotypes	1.518886e-4
GO:0032713	negative regulation of interleukin-4 production	1.549288e-4
GO:0050777	negative regulation of immune response	1.566742e-4
GO:0016126	sterol biosynthetic process	1.573695e-4
GO:0035630	bone mineralization involved in bone maturation	1.580952e-4
GO:0050748	negative regulation of lipoprotein metabolic process	1.635898e-4
GO:0043267	negative regulation of potassium ion transport	1.635898e-4
GO:0010155	regulation of proton transport	1.635898e-4
GO:0000255	allantoin metabolic process	1.648127e-4
GO:0046339	diacylglycerol metabolic process	1.651856e-4
GO:0072337	modified amino acid transport	1.654543e-4
GO:0042537	benzene-containing compound metabolic process	1.680092e-4
GO:0001508	regulation of action potential	1.724646e-4
GO:0009191	ribonucleoside diphosphate catabolic process	1.726806e-4
GO:0050918	positive chemotaxis	1.747540e-4
GO:0045824	negative regulation of innate immune response	1.815832e-4
GO:0032755	positive regulation of interleukin-6 production	1.851458e-4
GO:0050911	detection of chemical stimulus involved in sensory perception of smell	1.859662e-4
GO:0006012	galactose metabolic process	1.870745e-4
GO:0070670	response to interleukin-4	1.914516e-4
GO:0006099	tricarboxylic acid cycle	1.944911e-4
GO:0034370	triglyceride-rich lipoprotein particle remodeling	1.952738e-4
GO:0046356	acetyl-CoA catabolic process	1.977388e-4
GO:0060012	synaptic transmission, glycinergic	2.034723e-4
GO:0006507	GPI anchor release	2.034723e-4
GO:0002026	regulation of the force of heart contraction	2.049870e-4
GO:0060416	response to growth hormone stimulus	2.054010e-4
GO:0010574	regulation of vascular endothelial growth factor production	2.064246e-4
GO:0007586	digestion	2.082983e-4
GO:0042110	T cell activation	2.084166e-4
GO:0045821	positive regulation of glycolysis	2.105232e-4
GO:0014065	phosphatidylinositol 3-kinase cascade	2.143915e-4
GO:0050983	deoxyhypusine biosynthetic process from spermidine, using deoxyhypusine synthase	2.155683e-4
GO:0018872	arsonoacetate metabolic process	2.155683e-4
GO:0050856	regulation of T cell receptor signaling pathway	2.198377e-4
GO:0055002	striated muscle cell development	2.257048e-4
GO:0061037	negative regulation of cartilage development	2.285721e-4
GO:0019919	peptidyl-arginine methylation, to asymmetrical-dimethyl arginine	2.287928e-4
GO:0043901	negative regulation of multi-organism process	2.298999e-4
GO:0046640	regulation of alpha-beta T cell proliferation	2.307764e-4
GO:0071398	cellular response to fatty acid	2.340613e-4
GO:0019362	pyridine nucleotide metabolic process	2.345301e-4
GO:0060816	random inactivation of X chromosome	2.346745e-4
GO:0009746	response to hexose stimulus	2.379602e-4
GO:0009064	glutamine family amino acid metabolic process	2.385657e-4
GO:0031667	response to nutrient levels	2.401585e-4
GO:0031000	response to caffeine	2.425280e-4
GO:0071379	cellular response to prostaglandin stimulus	2.443469e-4
GO:0044282	small molecule catabolic process	2.460441e-4
GO:0045768	positive regulation of anti-apoptosis	2.464609e-4
GO:0044240	multicellular organismal lipid catabolic process	2.469355e-4
GO:0044106	cellular amine metabolic process	2.508834e-4
GO:0046709	IDP catabolic process	2.509362e-4
GO:0046032	ADP catabolic process	2.509362e-4
GO:0072592	oxygen metabolic process	2.511230e-4
GO:0009060	aerobic respiration	2.539323e-4
GO:0009308	amine metabolic process	2.612345e-4
GO:0002237	response to molecule of bacterial origin	2.626816e-4
GO:0060674	placenta blood vessel development	2.630336e-4
GO:0002252	immune effector process	2.682323e-4
GO:0032674	regulation of interleukin-5 production	2.746391e-4
GO:0070542	response to fatty acid	2.747064e-4
GO:0060711	labyrinthine layer development	2.753528e-4
GO:0051915	induction of synaptic plasticity by chemical substance	2.793575e-4
GO:0009404	toxin metabolic process	2.793575e-4
GO:0002883	regulation of hypersensitivity	2.796277e-4
GO:0006720	isoprenoid metabolic process	2.890842e-4
GO:0001775	cell activation	2.899204e-4
GO:0042445	hormone metabolic process	2.933082e-4
GO:0060402	calcium ion transport into cytosol	2.947539e-4
GO:0002821	positive regulation of adaptive immune response	2.948088e-4
GO:0061077	chaperone-mediated protein folding	2.978728e-4
GO:0007606	sensory perception of chemical stimulus	2.985542e-4
GO:0019693	ribose phosphate metabolic process	3.032193e-4
GO:0032714	negative regulation of interleukin-5 production	3.040829e-4
GO:0009615	response to virus	3.104393e-4
GO:0048878	chemical homeostasis	3.110511e-4
GO:0009593	detection of chemical stimulus	3.127537e-4
GO:0006695	cholesterol biosynthetic process	3.135893e-4
GO:0002923	regulation of humoral immune response mediated by circulating immunoglobulin	3.185431e-4
GO:0008050	female courtship behavior	3.219187e-4
GO:0072668	tubulin complex biogenesis	3.285844e-4
GO:0070309	lens fiber cell morphogenesis	3.285844e-4
GO:0046470	phosphatidylcholine metabolic process	3.405480e-4
GO:0002768	immune response-regulating cell surface receptor signaling pathway	3.408767e-4
GO:0010886	positive regulation of cholesterol storage	3.445098e-4
GO:0032844	regulation of homeostatic process	3.475544e-4
GO:0002699	positive regulation of immune effector process	3.534798e-4
GO:0030888	regulation of B cell proliferation	3.636876e-4
GO:0002861	regulation of inflammatory response to antigenic stimulus	3.640416e-4
GO:0009265	2'-deoxyribonucleotide biosynthetic process	3.696718e-4
GO:0043691	reverse cholesterol transport	3.708098e-4
GO:0006105	succinate metabolic process	3.719018e-4
GO:0045321	leukocyte activation	3.820827e-4
GO:0031100	organ regeneration	3.989619e-4
GO:0015851	nucleobase transport	4.022679e-4
GO:0046649	lymphocyte activation	4.082545e-4
GO:0045086	positive regulation of interleukin-2 biosynthetic process	4.103518e-4
GO:0030502	negative regulation of bone mineralization	4.127168e-4
GO:0044058	regulation of digestive system process	4.278273e-4
GO:0042592	homeostatic process	4.311806e-4
GO:0033574	response to testosterone stimulus	4.362413e-4
GO:0009134	nucleoside diphosphate catabolic process	4.407555e-4
GO:0070741	response to interleukin-6	4.437299e-4
GO:0006733	oxidoreduction coenzyme metabolic process	4.456306e-4
GO:0043154	negative regulation of caspase activity	4.518981e-4
GO:0014074	response to purine-containing compound	4.558036e-4
GO:0050857	positive regulation of antigen receptor-mediated signaling pathway	4.659854e-4
GO:0010994	free ubiquitin chain polymerization	4.713365e-4
GO:0010226	response to lithium ion	4.745067e-4
GO:0071320	cellular response to cAMP	4.761875e-4
GO:0002697	regulation of immune effector process	4.819532e-4
GO:0001558	regulation of cell growth	4.831547e-4
GO:0006520	cellular amino acid metabolic process	4.864207e-4
GO:0050868	negative regulation of T cell activation	4.900726e-4
GO:0042744	hydrogen peroxide catabolic process	4.915202e-4
GO:0009063	cellular amino acid catabolic process	4.997644e-4
GO:0006954	inflammatory response	5.077923e-4
GO:0051583	dopamine uptake	5.168445e-4
GO:0015747	urate transport	5.168445e-4
GO:0097029	mature dendritic cell differentiation	5.213114e-4
GO:0018106	peptidyl-histidine phosphorylation	5.266038e-4
GO:0048856	anatomical structure development	5.350207e-4
GO:0002679	respiratory burst involved in defense response	5.398294e-4
GO:0002695	negative regulation of leukocyte activation	5.458610e-4
GO:0031274	positive regulation of pseudopodium assembly	5.678230e-4
GO:0001701	in utero embryonic development	5.715182e-4
GO:0006863	purine base transport	5.893437e-4
GO:0051712	positive regulation of killing of cells of other organism	5.917998e-4
GO:0032496	response to lipopolysaccharide	5.925605e-4
GO:0070168	negative regulation of biomineral tissue development	5.958375e-4
GO:0045416	positive regulation of interleukin-8 biosynthetic process	6.314759e-4
GO:0034754	cellular hormone metabolic process	6.331126e-4
GO:0046651	lymphocyte proliferation	6.519744e-4
GO:0002885	positive regulation of hypersensitivity	6.546139e-4
GO:0045721	negative regulation of gluconeogenesis	6.614750e-4
GO:0006734	NADH metabolic process	6.646430e-4
GO:0070301	cellular response to hydrogen peroxide	6.781478e-4
GO:0042522	regulation of tyrosine phosphorylation of Stat5 protein	6.819561e-4
GO:0050927	positive regulation of positive chemotaxis	6.883949e-4
GO:0006548	histidine catabolic process	6.925737e-4
GO:0031952	regulation of protein autophosphorylation	6.977850e-4
GO:0032675	regulation of interleukin-6 production	6.979594e-4
GO:0008285	negative regulation of cell proliferation	7.032575e-4
GO:0034135	regulation of toll-like receptor 2 signaling pathway	7.172829e-4
GO:0018924	mandelate metabolic process	7.172829e-4
GO:0032386	regulation of intracellular transport	7.216161e-4
GO:0042447	hormone catabolic process	7.312280e-4
GO:0006873	cellular ion homeostasis	7.410173e-4
GO:0048015	phosphatidylinositol-mediated signaling	7.491491e-4
GO:0002149	hypochlorous acid biosynthetic process	7.552509e-4
GO:0000003	reproduction	7.623933e-4
GO:0030279	negative regulation of ossification	7.716253e-4
GO:0042542	response to hydrogen peroxide	7.784892e-4
GO:0048747	muscle fiber development	7.929314e-4
GO:0042403	thyroid hormone metabolic process	7.929499e-4
GO:0002429	immune response-activating cell surface receptor signaling pathway	7.948038e-4
GO:0045767	regulation of anti-apoptosis	7.995327e-4
GO:0048302	regulation of isotype switching to IgG isotypes	8.139723e-4
GO:0032387	negative regulation of intracellular transport	8.163798e-4
GO:0002253	activation of immune response	8.253162e-4
GO:0070661	leukocyte proliferation	8.440984e-4
GO:0060013	righting reflex	8.447156e-4
GO:0050996	positive regulation of lipid catabolic process	8.541267e-4
GO:0002118	aggressive behavior	8.596331e-4
GO:0008016	regulation of heart contraction	8.642804e-4
GO:0045338	farnesyl diphosphate metabolic process	8.741386e-4
GO:0006101	citrate metabolic process	8.959932e-4
GO:0009310	amine catabolic process	9.127339e-4
GO:0061061	muscle structure development	9.132990e-4
GO:0042692	muscle cell differentiation	9.216747e-4
GO:0010970	microtubule-based transport	9.293535e-4
GO:0009072	aromatic amino acid family metabolic process	9.322836e-4
GO:0043501	skeletal muscle adaptation	9.372908e-4
GO:0007021	tubulin complex assembly	9.376776e-4
GO:0055001	muscle cell development	9.411275e-4
GO:0010821	regulation of mitochondrion organization	9.519750e-4
GO:0002864	regulation of acute inflammatory response to antigenic stimulus	9.583250e-4
GO:0034614	cellular response to reactive oxygen species	9.618894e-4
GO:0032103	positive regulation of response to external stimulus	9.697054e-4
GO:0002824	positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains	9.744055e-4
GO:0031915	positive regulation of synaptic plasticity	9.754211e-4
GO:0009612	response to mechanical stimulus	1.007969e-3
GO:0009395	phospholipid catabolic process	1.009525e-3
GO:0051336	regulation of hydrolase activity	1.011407e-3
GO:0060900	embryonic camera-type eye formation	1.019166e-3
GO:0046395	carboxylic acid catabolic process	1.024887e-3
GO:0001915	negative regulation of T cell mediated cytotoxicity	1.053633e-3
GO:0048048	embryonic eye morphogenesis	1.053740e-3
GO:0008088	axon cargo transport	1.093357e-3
GO:0031116	positive regulation of microtubule polymerization	1.093357e-3
GO:0071615	oxidative deethylation	1.094241e-3
GO:0045090	retroviral genome replication	1.094241e-3
GO:0009403	toxin biosynthetic process	1.094241e-3
GO:0019556	histidine catabolic process to glutamate and formamide	1.094241e-3
GO:0007619	courtship behavior	1.095835e-3
GO:0033700	phospholipid efflux	1.108844e-3
GO:0048676	axon extension involved in development	1.110465e-3
GO:0051384	response to glucocorticoid stimulus	1.116080e-3
GO:0048738	cardiac muscle tissue development	1.116085e-3
GO:0023057	negative regulation of signaling	1.116332e-3
GO:0031016	pancreas development	1.120584e-3
GO:0045926	negative regulation of growth	1.121383e-3
GO:0030101	natural killer cell activation	1.129283e-3
GO:0007525	somatic muscle development	1.148903e-3
GO:0042346	positive regulation of NF-kappaB import into nucleus	1.152108e-3
GO:0042157	lipoprotein metabolic process	1.154516e-3
GO:0048662	negative regulation of smooth muscle cell proliferation	1.175425e-3
GO:0006641	triglyceride metabolic process	1.185765e-3
GO:0031272	regulation of pseudopodium assembly	1.190210e-3
GO:0019695	choline metabolic process	1.194589e-3
GO:0061029	eyelid development in camera-type eye	1.215394e-3
GO:0006812	cation transport	1.216455e-3
GO:0001960	negative regulation of cytokine-mediated signaling pathway	1.225311e-3