Novel motif:133

name:	motif133_TWTAWAGTWGRAG

Association to promoter expression in human samples<b>Summary:</b>Significance of the correlation with CAGE expression, human <br><b>Analyst:</b> Michiel de Hoon<br><br>link to source dataset <br>data

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Association to promoter expression in mouse samples <b>Summary:</b>Significance of the correlation with CAGE expression, mouse <br><b>Analyst:</b> Michiel de Hoon<br><br>link to source dataset <br>data

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GREAT analysis results for human <b>Summary:</b>Genomic Enrichment of Annotations Tool (GREAT, Nat Biotechnol. 2010 May;28(5):495-501) is used to identify, both in human and in mouse, the gene ontology terms of biological processes enriched given the predicted TFBSs, and evaluated the overlap in the top-500 gene ontology terms between human and mouse. For each novel motif, the P value for the overlap was then evaluated by calculating its relative rank with respect to this background distribution.<br>Analyst: Michiel de Hoon<br><br>link to source dataset <br>data

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GO ID	GO Term	p-value
GO:0048769	sarcomerogenesis	2.906072e-15
GO:0009888	tissue development	5.765323e-15
GO:0006887	exocytosis	5.609900e-14
GO:0055003	cardiac myofibril assembly	6.814355e-14
GO:0030240	skeletal muscle thin filament assembly	3.081614e-13
GO:0007076	mitotic chromosome condensation	3.704059e-13
GO:0060558	regulation of calcidiol 1-monooxygenase activity	5.016343e-13
GO:0030241	skeletal muscle myosin thick filament assembly	1.298310e-12
GO:0002576	platelet degranulation	5.996655e-12
GO:0032940	secretion by cell	7.612861e-12
GO:0042060	wound healing	2.112191e-11
GO:0055013	cardiac muscle cell development	2.572519e-11
GO:0032501	multicellular organismal process	4.259227e-11
GO:0048739	cardiac muscle fiber development	6.143741e-11
GO:0000819	sister chromatid segregation	6.902027e-11
GO:0000070	mitotic sister chromatid segregation	8.512720e-11
GO:0048679	regulation of axon regeneration	9.062702e-11
GO:0050790	regulation of catalytic activity	9.090092e-11
GO:0070571	negative regulation of neuron projection regeneration	1.083185e-10
GO:0030261	chromosome condensation	1.257025e-10
GO:0014866	skeletal myofibril assembly	1.351440e-10
GO:0048513	organ development	1.770099e-10
GO:0030168	platelet activation	2.188387e-10
GO:0065007	biological regulation	4.986415e-10
GO:0045214	sarcomere organization	5.489830e-10
GO:0050794	regulation of cellular process	6.941322e-10
GO:0065009	regulation of molecular function	1.140584e-9
GO:0060541	respiratory system development	1.872073e-9
GO:0050896	response to stimulus	2.471231e-9
GO:0017145	stem cell division	2.681376e-9
GO:0045859	regulation of protein kinase activity	2.971549e-9
GO:0046903	secretion	3.076787e-9
GO:0010575	positive regulation vascular endothelial growth factor production	3.252891e-9
GO:0060485	mesenchyme development	4.517807e-9
GO:0050789	regulation of biological process	4.569478e-9
GO:0043549	regulation of kinase activity	4.926676e-9
GO:0010956	negative regulation of calcidiol 1-monooxygenase activity	5.066386e-9
GO:0030323	respiratory tube development	5.102902e-9
GO:0030324	lung development	5.276161e-9
GO:0048731	system development	6.641006e-9
GO:0030049	muscle filament sliding	7.407432e-9
GO:0014031	mesenchymal cell development	8.131188e-9
GO:0048103	somatic stem cell division	8.499043e-9
GO:0048762	mesenchymal cell differentiation	8.722738e-9
GO:0030239	myofibril assembly	9.822536e-9
GO:0010470	regulation of gastrulation	1.060073e-8
GO:0070252	actin-mediated cell contraction	1.237000e-8
GO:0046951	ketone body biosynthetic process	1.345698e-8
GO:0035051	cardiac cell differentiation	1.569355e-8
GO:0007596	blood coagulation	1.699249e-8
GO:0048685	negative regulation of collateral sprouting of intact axon in response to injury	1.798079e-8
GO:0046950	cellular ketone body metabolic process	1.804584e-8
GO:0007275	multicellular organismal development	1.857863e-8
GO:0007599	hemostasis	2.452368e-8
GO:0051338	regulation of transferase activity	2.687761e-8
GO:0070105	positive regulation of interleukin-6-mediated signaling pathway	3.140817e-8
GO:0001660	fever generation	3.404096e-8
GO:0010957	negative regulation of vitamin D biosynthetic process	4.302008e-8
GO:0021553	olfactory nerve development	4.330176e-8
GO:0080135	regulation of cellular response to stress	4.423007e-8
GO:0023052	signaling	6.318602e-8
GO:0051649	establishment of localization in cell	6.319538e-8
GO:0048871	multicellular organismal homeostasis	6.681577e-8
GO:0003007	heart morphogenesis	7.929266e-8
GO:0030048	actin filament-based movement	8.702842e-8
GO:0007059	chromosome segregation	9.767689e-8
GO:0048568	embryonic organ development	1.348488e-7
GO:0010038	response to metal ion	1.578945e-7
GO:0055007	cardiac muscle cell differentiation	1.692241e-7
GO:0031296	B cell costimulation	1.769054e-7
GO:0007154	cell communication	1.822092e-7
GO:0019220	regulation of phosphate metabolic process	1.846298e-7
GO:0060390	regulation of SMAD protein import into nucleus	2.026734e-7
GO:0051641	cellular localization	2.198889e-7
GO:0006941	striated muscle contraction	2.361114e-7
GO:0010936	negative regulation of macrophage cytokine production	2.376756e-7
GO:0050810	regulation of steroid biosynthetic process	2.710390e-7
GO:0014047	glutamate secretion	2.809603e-7
GO:0090287	regulation of cellular response to growth factor stimulus	2.988218e-7
GO:0060556	regulation of vitamin D biosynthetic process	3.019899e-7
GO:0065008	regulation of biological quality	3.085572e-7
GO:0070164	negative regulation of adiponectin secretion	3.088522e-7
GO:0035505	positive regulation of myosin light chain kinase activity	3.088522e-7
GO:0060355	positive regulation of cell adhesion molecule production	3.088522e-7
GO:0032502	developmental process	3.158241e-7
GO:0051592	response to calcium ion	3.305785e-7
GO:0050878	regulation of body fluid levels	3.391260e-7
GO:0019218	regulation of steroid metabolic process	3.479795e-7
GO:0030154	cell differentiation	3.946181e-7
GO:0031032	actomyosin structure organization	4.190094e-7
GO:0043507	positive regulation of JUN kinase activity	4.416973e-7
GO:0048856	anatomical structure development	4.522705e-7
GO:0070163	regulation of adiponectin secretion	4.705837e-7
GO:0048681	negative regulation of axon regeneration	4.839877e-7
GO:0051246	regulation of protein metabolic process	4.973612e-7
GO:0003127	detection of nodal flow	5.352588e-7
GO:0022602	ovulation cycle process	5.539976e-7
GO:0043009	chordate embryonic development	5.726013e-7
GO:0048869	cellular developmental process	5.795651e-7
GO:0048644	muscle organ morphogenesis	6.034144e-7
GO:0042325	regulation of phosphorylation	6.070737e-7
GO:0060429	epithelium development	6.715543e-7
GO:0055008	cardiac muscle tissue morphogenesis	7.202768e-7
GO:0009790	embryo development	7.302982e-7
GO:0017156	calcium ion-dependent exocytosis	7.609429e-7
GO:0010574	regulation of vascular endothelial growth factor production	8.167513e-7
GO:0001659	temperature homeostasis	8.297325e-7
GO:0009611	response to wounding	8.299508e-7
GO:0045410	positive regulation of interleukin-6 biosynthetic process	8.304439e-7
GO:0032874	positive regulation of stress-activated MAPK cascade	8.352854e-7
GO:0050714	positive regulation of protein secretion	8.468555e-7
GO:0014033	neural crest cell differentiation	8.521770e-7
GO:0048729	tissue morphogenesis	8.949661e-7
GO:0009792	embryo development ending in birth or egg hatching	9.207449e-7
GO:0043623	cellular protein complex assembly	9.517897e-7
GO:0018352	protein-pyridoxal-5-phosphate linkage	9.718400e-7
GO:0001932	regulation of protein phosphorylation	1.157720e-6
GO:0032872	regulation of stress-activated MAPK cascade	1.270415e-6
GO:0007517	muscle organ development	1.318074e-6
GO:0030947	regulation of vascular endothelial growth factor receptor signaling pathway	1.351142e-6
GO:0001775	cell activation	1.482989e-6
GO:0060415	muscle tissue morphogenesis	1.630725e-6
GO:0060559	positive regulation of calcidiol 1-monooxygenase activity	1.691459e-6
GO:0021629	olfactory nerve structural organization	1.692374e-6
GO:0022601	menstrual cycle phase	1.733042e-6
GO:0006540	glutamate decarboxylation to succinate	1.783651e-6
GO:0006605	protein targeting	1.914305e-6
GO:0007389	pattern specification process	2.006140e-6
GO:0006713	glucocorticoid catabolic process	2.188931e-6
GO:0021903	rostrocaudal neural tube patterning	2.212443e-6
GO:0045833	negative regulation of lipid metabolic process	2.220727e-6
GO:0046849	bone remodeling	2.228774e-6
GO:0010927	cellular component assembly involved in morphogenesis	2.252069e-6
GO:0032725	positive regulation of granulocyte macrophage colony-stimulating factor production	2.328568e-6
GO:0048468	cell development	2.351722e-6
GO:0003002	regionalization	2.582226e-6
GO:0034116	positive regulation of heterotypic cell-cell adhesion	2.634118e-6
GO:0035282	segmentation	2.755083e-6
GO:0035295	tube development	2.957345e-6
GO:0007184	SMAD protein import into nucleus	2.983895e-6
GO:0030949	positive regulation of vascular endothelial growth factor receptor signaling pathway	3.416661e-6
GO:0007507	heart development	3.567518e-6
GO:0048585	negative regulation of response to stimulus	3.594600e-6
GO:0021795	cerebral cortex cell migration	3.651446e-6
GO:0048683	regulation of collateral sprouting of intact axon in response to injury	3.960029e-6
GO:0042698	ovulation cycle	4.173683e-6
GO:0007321	sperm displacement	4.322077e-6
GO:0006796	phosphate-containing compound metabolic process	4.598720e-6
GO:0031399	regulation of protein modification process	4.918836e-6
GO:0046952	ketone body catabolic process	5.134806e-6
GO:0080090	regulation of primary metabolic process	5.402110e-6
GO:0010756	positive regulation of plasminogen activation	5.466658e-6
GO:0045408	regulation of interleukin-6 biosynthetic process	5.602029e-6
GO:0042129	regulation of T cell proliferation	5.665832e-6
GO:0050768	negative regulation of neurogenesis	6.738767e-6
GO:0010894	negative regulation of steroid biosynthetic process	6.771572e-6
GO:0007420	brain development	6.994294e-6
GO:0033129	positive regulation of histone phosphorylation	7.816032e-6
GO:0009952	anterior/posterior pattern specification	8.007152e-6
GO:0090310	negative regulation of methylation-dependent chromatin silencing	8.180063e-6
GO:0050708	regulation of protein secretion	8.549664e-6
GO:0048747	muscle fiber development	8.589472e-6
GO:0007417	central nervous system development	8.926327e-6
GO:0071639	positive regulation of monocyte chemotactic protein-1 production	9.908931e-6
GO:0045939	negative regulation of steroid metabolic process	1.015427e-5
GO:0010693	negative regulation of alkaline phosphatase activity	1.049260e-5
GO:0080134	regulation of response to stress	1.109842e-5
GO:0032989	cellular component morphogenesis	1.166073e-5
GO:0045995	regulation of embryonic development	1.166770e-5
GO:0045785	positive regulation of cell adhesion	1.183089e-5
GO:0060427	lung connective tissue development	1.316048e-5
GO:0007165	signal transduction	1.323034e-5
GO:0006323	DNA packaging	1.332433e-5
GO:0014032	neural crest cell development	1.380259e-5
GO:0030730	sequestering of triglyceride	1.396184e-5
GO:0060391	positive regulation of SMAD protein import into nucleus	1.428897e-5
GO:0006468	protein phosphorylation	1.429815e-5
GO:0001837	epithelial to mesenchymal transition	1.558699e-5
GO:0033198	response to ATP	1.670555e-5
GO:0048583	regulation of response to stimulus	1.693564e-5
GO:0043506	regulation of JUN kinase activity	1.762167e-5
GO:0046890	regulation of lipid biosynthetic process	1.774103e-5
GO:0044093	positive regulation of molecular function	1.870012e-5
GO:0043086	negative regulation of catalytic activity	1.881253e-5
GO:0031424	keratinization	1.902572e-5
GO:0055002	striated muscle cell development	1.908552e-5
GO:0050778	positive regulation of immune response	1.910805e-5
GO:0010634	positive regulation of epithelial cell migration	1.931695e-5
GO:0071637	regulation of monocyte chemotactic protein-1 production	1.932021e-5
GO:0070543	response to linoleic acid	1.960731e-5
GO:0034696	response to prostaglandin F stimulus	1.960731e-5
GO:0006037	cell wall chitin metabolic process	1.960731e-5
GO:0051044	positive regulation of membrane protein ectodomain proteolysis	1.977916e-5
GO:0018065	protein-cofactor linkage	2.046124e-5
GO:0032768	regulation of monooxygenase activity	2.199216e-5
GO:0001755	neural crest cell migration	2.236140e-5
GO:0010193	response to ozone	2.237629e-5
GO:0003006	developmental process involved in reproduction	2.260942e-5
GO:0006953	acute-phase response	2.359614e-5
GO:0048704	embryonic skeletal system morphogenesis	2.388886e-5
GO:0019222	regulation of metabolic process	2.463590e-5
GO:0014051	gamma-aminobutyric acid secretion	2.514286e-5
GO:0007267	cell-cell signaling	2.556034e-5
GO:0050672	negative regulation of lymphocyte proliferation	2.602318e-5
GO:0060218	hemopoietic stem cell differentiation	2.736548e-5
GO:0071786	endoplasmic reticulum tubular network organization	2.742268e-5
GO:0051930	regulation of sensory perception of pain	2.781601e-5
GO:0010646	regulation of cell communication	2.905163e-5
GO:0043085	positive regulation of catalytic activity	2.924992e-5
GO:0010811	positive regulation of cell-substrate adhesion	3.014369e-5
GO:0070663	regulation of leukocyte proliferation	3.020204e-5
GO:0014805	smooth muscle adaptation	3.105873e-5
GO:0008585	female gonad development	3.281779e-5
GO:0032268	regulation of cellular protein metabolic process	3.337030e-5
GO:0010721	negative regulation of cell development	3.383711e-5
GO:0016560	protein import into peroxisome matrix, docking	3.421097e-5
GO:0090308	regulation of methylation-dependent chromatin silencing	3.467694e-5
GO:0033092	positive regulation of immature T cell proliferation in thymus	3.653511e-5
GO:0019538	protein metabolic process	3.783598e-5
GO:0001892	embryonic placenta development	3.845651e-5
GO:0006950	response to stress	3.862234e-5
GO:0016310	phosphorylation	3.908813e-5
GO:0008283	cell proliferation	3.928949e-5
GO:0030198	extracellular matrix organization	4.052806e-5
GO:0014050	negative regulation of glutamate secretion	4.108516e-5
GO:0045884	regulation of survival gene product expression	4.113987e-5
GO:0046690	response to tellurium ion	4.140936e-5
GO:0009645	response to low light intensity stimulus	4.140936e-5
GO:0031958	corticosteroid receptor signaling pathway	4.297059e-5
GO:0021532	neural tube patterning	4.464917e-5
GO:0010453	regulation of cell fate commitment	5.063777e-5
GO:0031323	regulation of cellular metabolic process	5.118899e-5
GO:0045087	innate immune response	5.234850e-5
GO:0009726	detection of endogenous stimulus	6.243289e-5
GO:0055001	muscle cell development	6.247900e-5
GO:0048706	embryonic skeletal system development	6.256628e-5
GO:0001553	luteinization	6.280070e-5
GO:0042789	mRNA transcription from RNA polymerase II promoter	6.346017e-5
GO:0060537	muscle tissue development	6.412148e-5
GO:0090276	regulation of peptide hormone secretion	6.558502e-5
GO:0001701	in utero embryonic development	6.687746e-5
GO:0006928	cellular component movement	6.715428e-5
GO:0045086	positive regulation of interleukin-2 biosynthetic process	6.758505e-5
GO:0032770	positive regulation of monooxygenase activity	7.038056e-5
GO:0030155	regulation of cell adhesion	7.188759e-5
GO:0033084	regulation of immature T cell proliferation in thymus	7.327528e-5
GO:0050796	regulation of insulin secretion	7.328125e-5
GO:0051781	positive regulation of cell division	7.460992e-5
GO:0060317	cardiac epithelial to mesenchymal transition	7.855302e-5
GO:0032645	regulation of granulocyte macrophage colony-stimulating factor production	7.855302e-5
GO:0042659	regulation of cell fate specification	8.264749e-5
GO:0048671	negative regulation of collateral sprouting	8.412311e-5
GO:0030728	ovulation	8.478867e-5
GO:0032769	negative regulation of monooxygenase activity	8.530643e-5
GO:0030432	peristalsis	8.796312e-5
GO:0050670	regulation of lymphocyte proliferation	8.863504e-5
GO:0022029	telencephalon cell migration	8.936818e-5
GO:0071103	DNA conformation change	9.105362e-5
GO:0033280	response to vitamin D	9.462990e-5
GO:0061039	ovum-producing ovary development	9.882336e-5
GO:0046825	regulation of protein export from nucleus	9.925728e-5
GO:0060658	nipple morphogenesis	9.929846e-5
GO:0006538	glutamate catabolic process	9.929846e-5
GO:0048511	rhythmic process	1.003367e-4
GO:0070587	regulation of cell-cell adhesion involved in gastrulation	1.003411e-4
GO:0034114	regulation of heterotypic cell-cell adhesion	1.003411e-4
GO:0045634	regulation of melanocyte differentiation	1.004364e-4
GO:0002439	chronic inflammatory response to antigenic stimulus	1.004364e-4
GO:0060612	adipose tissue development	1.009569e-4
GO:0070103	regulation of interleukin-6-mediated signaling pathway	1.020377e-4
GO:0035264	multicellular organism growth	1.027557e-4
GO:0045885	positive regulation of survival gene product expression	1.043317e-4
GO:0048519	negative regulation of biological process	1.065136e-4
GO:0060448	dichotomous subdivision of terminal units involved in lung branching	1.091716e-4
GO:0045579	positive regulation of B cell differentiation	1.098427e-4
GO:0002682	regulation of immune system process	1.104416e-4
GO:0046545	development of primary female sexual characteristics	1.118179e-4
GO:0003008	system process	1.122012e-4
GO:0051336	regulation of hydrolase activity	1.142116e-4
GO:0015812	gamma-aminobutyric acid transport	1.142630e-4
GO:0051716	cellular response to stimulus	1.145397e-4
GO:0002791	regulation of peptide secretion	1.171363e-4
GO:0060249	anatomical structure homeostasis	1.192106e-4
GO:0003012	muscle system process	1.198920e-4
GO:0050863	regulation of T cell activation	1.203113e-4
GO:0002260	lymphocyte homeostasis	1.208798e-4
GO:0032308	positive regulation of prostaglandin secretion	1.223271e-4
GO:0006015	5-phosphoribose 1-diphosphate biosynthetic process	1.246337e-4
GO:0050771	negative regulation of axonogenesis	1.247045e-4
GO:0032944	regulation of mononuclear cell proliferation	1.270156e-4
GO:0070664	negative regulation of leukocyte proliferation	1.343124e-4
GO:0050776	regulation of immune response	1.359455e-4
GO:0034014	response to triglyceride	1.385321e-4
GO:0032350	regulation of hormone metabolic process	1.398712e-4
GO:0001776	leukocyte homeostasis	1.420495e-4
GO:0061153	trachea gland development	1.491641e-4
GO:2000134	negative regulation of G1/S transition of mitotic cell cycle	1.491641e-4
GO:0001561	fatty acid alpha-oxidation	1.491641e-4
GO:0051249	regulation of lymphocyte activation	1.540578e-4
GO:0008207	C21-steroid hormone metabolic process	1.554148e-4
GO:0006913	nucleocytoplasmic transport	1.572580e-4
GO:0021885	forebrain cell migration	1.617332e-4
GO:0010632	regulation of epithelial cell migration	1.641640e-4
GO:0048738	cardiac muscle tissue development	1.647081e-4
GO:0007015	actin filament organization	1.662373e-4
GO:0006955	immune response	1.663716e-4
GO:0033591	response to L-ascorbic acid	1.697012e-4
GO:0007492	endoderm development	1.819487e-4
GO:0033127	regulation of histone phosphorylation	1.874844e-4
GO:0048608	reproductive structure development	1.931044e-4
GO:0006089	lactate metabolic process	1.938752e-4
GO:0008037	cell recognition	1.944864e-4
GO:0010035	response to inorganic substance	1.948214e-4
GO:0055108	Golgi to transport vesicle transport	1.961614e-4
GO:0034418	urate biosynthetic process	1.961614e-4
GO:0070302	regulation of stress-activated protein kinase signaling cascade	1.986008e-4
GO:0002369	T cell cytokine production	1.986383e-4
GO:0001771	immunological synapse formation	1.986383e-4
GO:0060022	hard palate development	2.067074e-4
GO:0051169	nuclear transport	2.094259e-4
GO:0001890	placenta development	2.141765e-4
GO:0046827	positive regulation of protein export from nucleus	2.150954e-4
GO:0042637	catagen	2.216732e-4
GO:0060562	epithelial tube morphogenesis	2.247287e-4
GO:0008544	epidermis development	2.266434e-4
GO:0070668	positive regulation of mast cell proliferation	2.280064e-4
GO:0070271	protein complex biogenesis	2.295932e-4
GO:0032909	regulation of transforming growth factor beta2 production	2.311619e-4
GO:0002636	positive regulation of germinal center formation	2.391289e-4
GO:0048305	immunoglobulin secretion	2.391289e-4
GO:0048523	negative regulation of cellular process	2.398754e-4
GO:0006606	protein import into nucleus	2.423658e-4
GO:0006461	protein complex assembly	2.433984e-4
GO:0016079	synaptic vesicle exocytosis	2.459799e-4
GO:0048489	synaptic vesicle transport	2.510801e-4
GO:0060152	microtubule-based peroxisome localization	2.588311e-4
GO:0043488	regulation of mRNA stability	2.645712e-4
GO:0046660	female sex differentiation	2.746437e-4
GO:0046339	diacylglycerol metabolic process	2.781050e-4
GO:0021801	cerebral cortex radial glia guided migration	2.781050e-4
GO:0051223	regulation of protein transport	2.791223e-4
GO:0000122	negative regulation of transcription from RNA polymerase II promoter	2.843828e-4
GO:0050995	negative regulation of lipid catabolic process	2.945492e-4
GO:0003017	lymph circulation	2.953449e-4
GO:0040007	growth	2.961140e-4
GO:0071822	protein complex subunit organization	2.973524e-4
GO:0045726	positive regulation of integrin biosynthetic process	2.990493e-4
GO:0051302	regulation of cell division	3.026970e-4
GO:0023057	negative regulation of signaling	3.065483e-4
GO:0002719	negative regulation of cytokine production involved in immune response	3.089545e-4
GO:0006465	signal peptide processing	3.093782e-4
GO:0010648	negative regulation of cell communication	3.134921e-4
GO:0023051	regulation of signaling	3.150088e-4
GO:0070201	regulation of establishment of protein localization	3.179020e-4
GO:0022603	regulation of anatomical structure morphogenesis	3.226360e-4
GO:0001945	lymph vessel development	3.243277e-4
GO:0060255	regulation of macromolecule metabolic process	3.275965e-4
GO:0051170	nuclear import	3.520058e-4
GO:0070483	detection of hypoxia	3.613934e-4
GO:0045213	neurotransmitter receptor metabolic process	3.647206e-4
GO:0046627	negative regulation of insulin receptor signaling pathway	3.706990e-4
GO:0035020	regulation of Rac protein signal transduction	3.719003e-4
GO:0033674	positive regulation of kinase activity	3.806611e-4
GO:0021543	pallium development	3.837775e-4
GO:0044060	regulation of endocrine process	3.849579e-4
GO:0032352	positive regulation of hormone metabolic process	3.885795e-4
GO:0060364	frontal suture morphogenesis	3.909555e-4
GO:0035066	positive regulation of histone acetylation	3.927321e-4
GO:0071901	negative regulation of protein serine/threonine kinase activity	4.058735e-4
GO:0048646	anatomical structure formation involved in morphogenesis	4.113134e-4
GO:0014048	regulation of glutamate secretion	4.148384e-4
GO:0045076	regulation of interleukin-2 biosynthetic process	4.204236e-4
GO:0035690	cellular response to drug	4.252992e-4
GO:0032880	regulation of protein localization	4.379587e-4
GO:0043407	negative regulation of MAP kinase activity	4.408664e-4
GO:0045860	positive regulation of protein kinase activity	4.427825e-4
GO:0060345	spleen trabecula formation	4.493133e-4
GO:0043441	acetoacetic acid biosynthetic process	4.514483e-4
GO:0010810	regulation of cell-substrate adhesion	4.582430e-4
GO:0051179	localization	4.596220e-4
GO:0030838	positive regulation of actin filament polymerization	4.598877e-4
GO:0046716	muscle cell homeostasis	4.619682e-4
GO:2000193	positive regulation of fatty acid transport	4.724088e-4
GO:0022414	reproductive process	4.752047e-4
GO:0000003	reproduction	4.783767e-4
GO:0046885	regulation of hormone biosynthetic process	4.810927e-4
GO:0031622	positive regulation of fever generation	4.854017e-4
GO:0002711	positive regulation of T cell mediated immunity	4.883111e-4
GO:0007413	axonal fasciculation	4.883111e-4
GO:0035510	DNA dealkylation	4.929832e-4
GO:0051341	regulation of oxidoreductase activity	4.935283e-4
GO:0030316	osteoclast differentiation	5.073927e-4
GO:0051222	positive regulation of protein transport	5.074707e-4
GO:0051795	positive regulation of catagen	5.162629e-4
GO:0031987	locomotion involved in locomotory behavior	5.162629e-4
GO:0030855	epithelial cell differentiation	5.242189e-4
GO:0014706	striated muscle tissue development	5.300910e-4
GO:0030318	melanocyte differentiation	5.331076e-4
GO:0043619	regulation of transcription from RNA polymerase II promoter in response to oxidative stress	5.343279e-4
GO:0035721	intraflagellar retrograde transport	5.348957e-4
GO:0007155	cell adhesion	5.368612e-4
GO:0033083	regulation of immature T cell proliferation	5.395400e-4
GO:0010692	regulation of alkaline phosphatase activity	5.399321e-4
GO:0045778	positive regulation of ossification	5.427413e-4
GO:0051382	kinetochore assembly	5.620204e-4
GO:0021846	cell proliferation in forebrain	5.654942e-4
GO:0016192	vesicle-mediated transport	5.689819e-4
GO:0043932	ossification involved in bone remodeling	5.806879e-4
GO:0033091	positive regulation of immature T cell proliferation	5.811607e-4
GO:0080111	DNA demethylation	5.816426e-4
GO:0031295	T cell costimulation	5.911223e-4
GO:0008211	glucocorticoid metabolic process	5.974809e-4
GO:0006886	intracellular protein transport	6.003925e-4
GO:0001657	ureteric bud development	6.046475e-4
GO:0009968	negative regulation of signal transduction	6.067960e-4
GO:0002684	positive regulation of immune system process	6.093303e-4
GO:0048702	embryonic neurocranium morphogenesis	6.108639e-4
GO:0009299	mRNA transcription	6.184032e-4
GO:0007567	parturition	6.237324e-4
GO:0007368	determination of left/right symmetry	6.285736e-4
GO:0043170	macromolecule metabolic process	6.314130e-4
GO:0048598	embryonic morphogenesis	6.318863e-4
GO:0045636	positive regulation of melanocyte differentiation	6.332579e-4
GO:0042130	negative regulation of T cell proliferation	6.391037e-4
GO:0007268	synaptic transmission	6.393931e-4
GO:0071397	cellular response to cholesterol	6.419079e-4
GO:0009649	entrainment of circadian clock	6.518658e-4
GO:0031652	positive regulation of heat generation	6.709049e-4
GO:0048670	regulation of collateral sprouting	6.738984e-4
GO:0002218	activation of innate immune response	6.881611e-4
GO:0070723	response to cholesterol	6.904145e-4
GO:0002824	positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains	7.051830e-4
GO:0048818	positive regulation of hair follicle maturation	7.183735e-4
GO:0010002	cardioblast differentiation	7.183735e-4
GO:0002526	acute inflammatory response	7.185480e-4
GO:0021930	cerebellar granule cell precursor proliferation	7.336852e-4
GO:0046358	butyrate biosynthetic process	7.336852e-4
GO:0033197	response to vitamin E	7.684263e-4
GO:0051383	kinetochore organization	7.773285e-4
GO:0045113	regulation of integrin biosynthetic process	7.773285e-4
GO:0061061	muscle structure development	7.778508e-4
GO:0007229	integrin-mediated signaling pathway	7.808787e-4
GO:0008406	gonad development	7.892637e-4
GO:0002709	regulation of T cell mediated immunity	7.925435e-4
GO:0014821	phasic smooth muscle contraction	8.008014e-4
GO:0002253	activation of immune response	8.171310e-4
GO:0021957	corticospinal tract morphogenesis	8.248330e-4
GO:0051354	negative regulation of oxidoreductase activity	8.249824e-4
GO:0046415	urate metabolic process	8.288032e-4
GO:0034622	cellular macromolecular complex assembly	8.292775e-4
GO:0051347	positive regulation of transferase activity	8.386599e-4
GO:0045089	positive regulation of innate immune response	8.388494e-4
GO:0010977	negative regulation of neuron projection development	8.398413e-4
GO:0051251	positive regulation of lymphocyte activation	8.451951e-4
GO:0032892	positive regulation of organic acid transport	8.497761e-4
GO:0023061	signal release	8.502869e-4
GO:0043487	regulation of RNA stability	8.543264e-4
GO:0033026	negative regulation of mast cell apoptosis	8.544923e-4
GO:0030901	midbrain development	8.561408e-4
GO:0051043	regulation of membrane protein ectodomain proteolysis	8.680626e-4
GO:0050870	positive regulation of T cell activation	8.728194e-4
GO:0002437	inflammatory response to antigenic stimulus	8.751948e-4
GO:0034605	cellular response to heat	8.761222e-4
GO:0007566	embryo implantation	8.792168e-4
GO:0050996	positive regulation of lipid catabolic process	8.823603e-4
GO:0010829	negative regulation of glucose transport	8.904396e-4
GO:0042447	hormone catabolic process	8.942881e-4
GO:2000172	regulation of branching morphogenesis of a nerve	9.007855e-4
GO:0043412	macromolecule modification	9.019049e-4
GO:0046688	response to copper ion	9.023013e-4
GO:0035162	embryonic hemopoiesis	9.037890e-4
GO:0009972	cytidine deamination	9.123328e-4
GO:0001756	somitogenesis	9.126437e-4
GO:0030900	forebrain development	9.165642e-4
GO:0007399	nervous system development	9.214631e-4
GO:0051047	positive regulation of secretion	9.324118e-4
GO:0051093	negative regulation of developmental process	9.336044e-4
GO:0001822	kidney development	9.344837e-4
GO:0009799	specification of symmetry	9.345740e-4
GO:0009887	organ morphogenesis	9.682169e-4
GO:0030423	targeting of mRNA for destruction involved in RNA interference	9.796580e-4
GO:0019731	antibacterial humoral response	9.796580e-4
GO:0009756	carbohydrate mediated signaling	1.003602e-3
GO:0048532	anatomical structure arrangement	1.005004e-3
GO:0030512	negative regulation of transforming growth factor beta receptor signaling pathway	1.031318e-3
GO:0001667	ameboidal cell migration	1.036599e-3
GO:0006936	muscle contraction	1.047594e-3
GO:0031345	negative regulation of cell projection organization	1.052846e-3
GO:0042102	positive regulation of T cell proliferation	1.054243e-3
GO:0019933	cAMP-mediated signaling	1.073708e-3
GO:0070304	positive regulation of stress-activated protein kinase signaling cascade	1.078071e-3
GO:0019932	second-messenger-mediated signaling	1.084412e-3
GO:0042073	intraflagellar transport	1.122091e-3
GO:0035994	response to muscle stretch	1.122091e-3
GO:0031579	membrane raft organization	1.146295e-3
GO:0006105	succinate metabolic process	1.146295e-3
GO:0021799	cerebral cortex radially oriented cell migration	1.146582e-3
GO:0030279	negative regulation of ossification	1.154052e-3
GO:0009855	determination of bilateral symmetry	1.193535e-3
GO:0043620	regulation of DNA-dependent transcription in response to stress	1.196504e-3

GREAT analysis results for mouseGenomic Enrichment of Annotations Tool (GREAT, Nat Biotechnol. 2010 May;28(5):495-501) is used to identify, both in human and in mouse, the gene ontology terms of biological processes enriched given the predicted TFBSs, and evaluated the overlap in the top-500 gene ontology terms between human and mouse. For each novel motif, the P value for the overlap was then evaluated by calculating its relative rank with respect to this background distribution.<br>Analyst: Michiel de Hoon <br><br>link to source dataset <br>data

---

GO ID	GO Term	p-value
GO:0021891	olfactory bulb interneuron development	9.190170e-9
GO:0034638	phosphatidylcholine catabolic process	1.041744e-8
GO:0006713	glucocorticoid catabolic process	1.319447e-8
GO:0030900	forebrain development	3.928887e-8
GO:0008208	C21-steroid hormone catabolic process	4.173342e-8
GO:0021889	olfactory bulb interneuron differentiation	5.169453e-8
GO:0032418	lysosome localization	3.615091e-7
GO:0007417	central nervous system development	3.667224e-7
GO:0007420	brain development	4.404957e-7
GO:0090179	planar cell polarity pathway involved in neural tube closure	4.520065e-7
GO:0051640	organelle localization	6.885758e-7
GO:0002011	morphogenesis of an epithelial sheet	7.765739e-7
GO:0045176	apical protein localization	9.600683e-7
GO:0009952	anterior/posterior pattern specification	1.069887e-6
GO:0046475	glycerophospholipid catabolic process	1.364560e-6
GO:0060601	lateral sprouting from an epithelium	1.436788e-6
GO:0031570	DNA integrity checkpoint	1.590906e-6
GO:0070845	polyubiquitinated misfolded protein transport	2.585655e-6
GO:0014823	response to activity	2.671210e-6
GO:0045843	negative regulation of striated muscle tissue development	2.693907e-6
GO:0001736	establishment of planar polarity	3.336226e-6
GO:0048642	negative regulation of skeletal muscle tissue development	3.606074e-6
GO:0090177	establishment of planar polarity involved in neural tube closure	3.711721e-6
GO:0042351	'de novo' GDP-L-fucose biosynthetic process	3.711721e-6
GO:2000761	positive regulation of N-terminal peptidyl-lysine acetylation	3.720643e-6
GO:0035910	ascending aorta morphogenesis	3.720643e-6
GO:0090042	tubulin deacetylation	4.143875e-6
GO:0070846	Hsp90 deacetylation	4.143875e-6
GO:0015739	sialic acid transport	4.143875e-6
GO:0060029	convergent extension involved in organogenesis	4.148121e-6
GO:0021543	pallium development	4.445236e-6
GO:0021836	chemorepulsion involved in postnatal olfactory bulb interneuron migration	4.783227e-6
GO:0090068	positive regulation of cell cycle process	4.943042e-6
GO:0048635	negative regulation of muscle organ development	4.964632e-6
GO:0046186	acetaldehyde biosynthetic process	5.189466e-6
GO:0021827	postnatal olfactory bulb interneuron migration	5.384840e-6
GO:0007164	establishment of tissue polarity	5.861876e-6
GO:0045836	positive regulation of meiosis	6.741088e-6
GO:0007095	mitotic cell cycle G2/M transition DNA damage checkpoint	8.482401e-6
GO:0030953	astral microtubule organization	8.835433e-6
GO:0000077	DNA damage checkpoint	8.858077e-6
GO:0042769	DNA damage response, detection of DNA damage	9.053675e-6
GO:0001837	epithelial to mesenchymal transition	9.138183e-6
GO:0050925	negative regulation of negative chemotaxis	1.190208e-5
GO:0060489	planar dichotomous subdivision of terminal units involved in lung branching morphogenesis	1.249880e-5
GO:0060488	orthogonal dichotomous subdivision of terminal units involved in lung branching morphogenesis	1.249880e-5
GO:0060490	lateral sprouting involved in lung morphogenesis	1.249880e-5
GO:0048105	establishment of body hair planar orientation	1.249880e-5
GO:0042350	GDP-L-fucose biosynthetic process	1.249880e-5
GO:0007166	cell surface receptor linked signaling pathway	1.252493e-5
GO:0048853	forebrain morphogenesis	1.289185e-5
GO:0007093	mitotic cell cycle checkpoint	1.327388e-5
GO:0060071	Wnt receptor signaling pathway, planar cell polarity pathway	1.463949e-5
GO:0001738	morphogenesis of a polarized epithelium	1.549681e-5
GO:0050922	negative regulation of chemotaxis	1.636524e-5
GO:0021800	cerebral cortex tangential migration	1.877437e-5
GO:0001756	somitogenesis	1.993795e-5
GO:0006069	ethanol oxidation	2.067859e-5
GO:0060026	convergent extension	2.342420e-5
GO:0008105	asymmetric protein localization	2.342420e-5
GO:0002328	pro-B cell differentiation	2.486422e-5
GO:0061351	neural precursor cell proliferation	2.519522e-5
GO:0046184	aldehyde biosynthetic process	2.607771e-5
GO:0071780	mitotic cell cycle G2/M transition checkpoint	2.699607e-5
GO:0046826	negative regulation of protein export from nucleus	2.699607e-5
GO:0090035	positive regulation of cellular chaperone-mediated protein complex assembly	2.785569e-5
GO:0070884	regulation of calcineurin-NFAT signaling pathway	2.785569e-5
GO:0090009	primitive streak formation	2.839791e-5
GO:0035567	non-canonical Wnt receptor signaling pathway	3.032932e-5
GO:0002009	morphogenesis of an epithelium	3.143077e-5
GO:0030050	vesicle transport along actin filament	3.233585e-5
GO:0006068	ethanol catabolic process	3.251040e-5
GO:2000602	regulation of interphase of mitotic cell cycle	3.261183e-5
GO:0010845	positive regulation of reciprocal meiotic recombination	3.973033e-5
GO:0021846	cell proliferation in forebrain	4.010702e-5
GO:0070100	negative regulation of chemokine-mediated signaling pathway	4.064496e-5
GO:0050923	regulation of negative chemotaxis	4.064496e-5
GO:0003289	atrial septum primum morphogenesis	4.671934e-5
GO:0048103	somatic stem cell division	4.741995e-5
GO:0060448	dichotomous subdivision of terminal units involved in lung branching	4.900991e-5
GO:0006067	ethanol metabolic process	4.900991e-5
GO:0060028	convergent extension involved in axis elongation	4.900991e-5
GO:0061053	somite development	5.155392e-5
GO:0017145	stem cell division	5.281939e-5
GO:0051648	vesicle localization	5.288527e-5
GO:0021537	telencephalon development	5.350520e-5
GO:0071109	superior temporal gyrus development	5.492380e-5
GO:0043162	ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway	5.492380e-5
GO:0003323	type B pancreatic cell development	5.623241e-5
GO:0035385	Roundabout signaling pathway	5.725418e-5
GO:0021510	spinal cord development	5.809622e-5
GO:0050919	negative chemotaxis	6.584028e-5
GO:0016202	regulation of striated muscle tissue development	6.622878e-5
GO:0031572	G2/M transition DNA damage checkpoint	6.695901e-5
GO:0016199	axon midline choice point recognition	6.795806e-5
GO:0048852	diencephalon morphogenesis	6.850449e-5
GO:0072331	signal transduction by p53 class mediator	7.107269e-5
GO:0060369	positive regulation of Fc receptor mediated stimulatory signaling pathway	7.395585e-5
GO:0048521	negative regulation of behavior	7.537739e-5
GO:0048634	regulation of muscle organ development	8.003315e-5
GO:0031647	regulation of protein stability	8.167889e-5
GO:0045163	clustering of voltage-gated potassium channels	8.506587e-5
GO:0060411	cardiac septum morphogenesis	8.657757e-5
GO:0032060	bleb assembly	9.556031e-5
GO:0008057	eye pigment granule organization	9.737056e-5
GO:0060763	mammary duct terminal end bud growth	1.021042e-4
GO:0035909	aorta morphogenesis	1.024019e-4
GO:0048854	brain morphogenesis	1.027917e-4
GO:0032024	positive regulation of insulin secretion	1.042811e-4
GO:0050774	negative regulation of dendrite morphogenesis	1.077543e-4
GO:0032400	melanosome localization	1.105720e-4
GO:0006977	DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest	1.142564e-4
GO:0048864	stem cell development	1.173670e-4
GO:0048598	embryonic morphogenesis	1.205466e-4
GO:0014031	mesenchymal cell development	1.264107e-4
GO:0048729	tissue morphogenesis	1.266195e-4
GO:0071158	positive regulation of cell cycle arrest	1.272598e-4
GO:0006666	3-keto-sphinganine metabolic process	1.316803e-4
GO:0009229	thiamine diphosphate biosynthetic process	1.316803e-4
GO:0048632	negative regulation of skeletal muscle tissue growth	1.316803e-4
GO:0007285	primary spermatocyte growth	1.316803e-4
GO:0035019	somatic stem cell maintenance	1.344308e-4
GO:0006117	acetaldehyde metabolic process	1.386900e-4
GO:0019836	hemolysis by symbiont of host erythrocytes	1.468923e-4
GO:0003344	pericardium morphogenesis	1.518948e-4
GO:0072422	signal transduction involved in DNA damage checkpoint	1.594891e-4
GO:0019673	GDP-mannose metabolic process	1.613307e-4
GO:0060563	neuroepithelial cell differentiation	1.689884e-4
GO:0060340	positive regulation of type I interferon-mediated signaling pathway	1.694185e-4
GO:0043476	pigment accumulation	1.694185e-4
GO:0022007	convergent extension involved in neural plate elongation	1.866879e-4
GO:0019827	stem cell maintenance	1.993548e-4
GO:0046092	deoxycytidine metabolic process	1.996675e-4
GO:0033128	negative regulation of histone phosphorylation	1.996675e-4
GO:0050821	protein stabilization	2.144435e-4
GO:0042249	establishment of planar polarity of embryonic epithelium	2.149729e-4
GO:0000086	G2/M transition of mitotic cell cycle	2.452597e-4
GO:0061349	planar cell polarity pathway involved in cardiac right atrium morphogenesis	2.464038e-4
GO:0061354	planar cell polarity pathway involved in pericardium morphogenesis	2.464038e-4
GO:0061350	planar cell polarity pathway involved in cardiac muscle tissue morphogenesis	2.464038e-4
GO:0060210	metestrus	2.464038e-4
GO:0061347	planar cell polarity pathway involved in outflow tract morphogenesis	2.464038e-4
GO:0061348	planar cell polarity pathway involved in ventricular septum morphogenesis	2.464038e-4
GO:0060429	epithelium development	2.475116e-4
GO:0031571	mitotic cell cycle G1/S transition DNA damage checkpoint	2.495521e-4
GO:0042753	positive regulation of circadian rhythm	2.552769e-4
GO:0002042	cell migration involved in sprouting angiogenesis	2.591192e-4
GO:0031424	keratinization	2.718122e-4
GO:0046823	negative regulation of nucleocytoplasmic transport	2.732223e-4
GO:0051875	pigment granule localization	2.766367e-4
GO:2000049	positive regulation of cell-cell adhesion mediated by cadherin	2.812059e-4
GO:0022612	gland morphogenesis	2.812477e-4
GO:0046010	positive regulation of circadian sleep/wake cycle, non-REM sleep	2.839894e-4
GO:0003357	noradrenergic neuron differentiation	2.857359e-4
GO:0051865	protein autoubiquitination	2.970061e-4
GO:0001702	gastrulation with mouth forming second	2.978726e-4
GO:0010464	regulation of mesenchymal cell proliferation	3.063974e-4
GO:0070885	negative regulation of calcineurin-NFAT signaling pathway	3.086207e-4
GO:0007369	gastrulation	3.182066e-4
GO:0031958	corticosteroid receptor signaling pathway	3.191404e-4
GO:0071205	protein localization to juxtaparanode region of axon	3.196110e-4
GO:0021987	cerebral cortex development	3.368092e-4
GO:0003309	type B pancreatic cell differentiation	3.566572e-4
GO:0090277	positive regulation of peptide hormone secretion	3.615841e-4
GO:0060067	cervix development	3.618573e-4
GO:0003183	mitral valve morphogenesis	3.752443e-4
GO:0035904	aorta development	3.994546e-4
GO:0060173	limb development	4.014816e-4
GO:0070541	response to platinum ion	4.121789e-4
GO:0060070	canonical Wnt receptor signaling pathway	4.150785e-4
GO:0001763	morphogenesis of a branching structure	4.155073e-4
GO:0003002	regionalization	4.189529e-4
GO:0007389	pattern specification process	4.239198e-4
GO:0007167	enzyme linked receptor protein signaling pathway	4.282290e-4
GO:0014732	skeletal muscle atrophy	4.474415e-4
GO:0002793	positive regulation of peptide secretion	4.514070e-4
GO:0060599	lateral sprouting involved in mammary gland duct morphogenesis	4.588574e-4
GO:0002741	positive regulation of cytokine secretion involved in immune response	4.588574e-4
GO:0000075	cell cycle checkpoint	4.611809e-4
GO:0031576	G2/M transition checkpoint	4.665429e-4
GO:0042472	inner ear morphogenesis	4.747551e-4
GO:0001959	regulation of cytokine-mediated signaling pathway	4.971629e-4
GO:0033160	positive regulation of protein import into nucleus, translocation	5.089125e-4
GO:0071671	regulation of smooth muscle cell chemotaxis	5.140037e-4
GO:0070842	aggresome assembly	5.140037e-4
GO:0043951	negative regulation of cAMP-mediated signaling	5.140037e-4
GO:0021536	diencephalon development	5.159948e-4
GO:0010224	response to UV-B	5.382453e-4
GO:0014850	response to muscle activity	5.382453e-4
GO:0010564	regulation of cell cycle process	5.559155e-4
GO:0060759	regulation of response to cytokine stimulus	5.733074e-4
GO:0051223	regulation of protein transport	5.872894e-4
GO:0008038	neuron recognition	5.911756e-4
GO:0016198	axon choice point recognition	6.019837e-4
GO:0060413	atrial septum morphogenesis	6.239211e-4
GO:0035282	segmentation	6.287951e-4
GO:0031018	endocrine pancreas development	6.547598e-4
GO:0060412	ventricular septum morphogenesis	6.550301e-4
GO:0051817	modification of morphology or physiology of other organism involved in symbiotic interaction	6.550301e-4
GO:0003283	atrial septum development	6.736260e-4
GO:0022027	interkinetic nuclear migration	7.095169e-4
GO:0048850	hypophysis morphogenesis	7.100900e-4
GO:0002702	positive regulation of production of molecular mediator of immune response	7.314758e-4
GO:0001841	neural tube formation	7.432290e-4
GO:0060907	positive regulation of macrophage cytokine production	7.555160e-4
GO:0090103	cochlea morphogenesis	7.583414e-4
GO:0006772	thiamine metabolic process	7.800804e-4
GO:0035239	tube morphogenesis	7.875605e-4
GO:0003230	cardiac atrium development	7.911300e-4
GO:0034754	cellular hormone metabolic process	7.996921e-4
GO:0009156	ribonucleoside monophosphate biosynthetic process	8.055857e-4
GO:0061138	morphogenesis of a branching epithelium	8.121177e-4
GO:0090102	cochlea development	8.175629e-4
GO:0001569	patterning of blood vessels	8.232252e-4
GO:0006929	substrate-dependent cell migration	8.303312e-4
GO:0021772	olfactory bulb development	8.410556e-4
GO:0048754	branching morphogenesis of a tube	8.463133e-4
GO:0014889	muscle atrophy	8.570200e-4
GO:0003306	Wnt receptor signaling pathway involved in heart development	8.576202e-4
GO:0021988	olfactory lobe development	8.619187e-4
GO:0046686	response to cadmium ion	9.120828e-4
GO:0003209	cardiac atrium morphogenesis	9.432461e-4
GO:0002053	positive regulation of mesenchymal cell proliferation	9.434010e-4
GO:0040020	regulation of meiosis	9.469948e-4
GO:0033574	response to testosterone stimulus	9.965928e-4
GO:0032235	negative regulation of calcium ion transport via store-operated calcium channel activity	1.002185e-3
GO:0010389	regulation of G2/M transition of mitotic cell cycle	1.017891e-3
GO:0090317	negative regulation of intracellular protein transport	1.053574e-3
GO:0035108	limb morphogenesis	1.055290e-3
GO:0072404	signal transduction involved in G1/S transition checkpoint	1.056684e-3
GO:0060600	dichotomous subdivision of an epithelial terminal unit	1.133598e-3
GO:0033600	negative regulation of mammary gland epithelial cell proliferation	1.148802e-3
GO:0021943	formation of radial glial scaffolds	1.148802e-3
GO:0002090	regulation of receptor internalization	1.148802e-3
GO:0023052	signaling	1.164202e-3
GO:0052312	modulation of transcription in other organism involved in symbiotic interaction	1.183708e-3
GO:0071156	regulation of cell cycle arrest	1.185974e-3
GO:0060788	ectodermal placode formation	1.199367e-3
GO:0048839	inner ear development	1.215210e-3
GO:0046689	response to mercury ion	1.233875e-3
GO:0071673	positive regulation of smooth muscle cell chemotaxis	1.260530e-3
GO:0006507	GPI anchor release	1.260530e-3
GO:2000484	positive regulation of interleukin-8 secretion	1.262810e-3
GO:0035295	tube development	1.284170e-3
GO:0045938	positive regulation of circadian sleep/wake cycle, sleep	1.295556e-3
GO:0071542	dopaminergic neuron differentiation	1.320102e-3
GO:0072395	signal transduction involved in cell cycle checkpoint	1.331143e-3
GO:0014009	glial cell proliferation	1.344856e-3
GO:0051445	regulation of meiotic cell cycle	1.346707e-3
GO:0003401	axis elongation	1.349755e-3
GO:0042471	ear morphogenesis	1.362295e-3
GO:0045188	regulation of circadian sleep/wake cycle, non-REM sleep	1.448473e-3
GO:0032880	regulation of protein localization	1.490168e-3
GO:0022409	positive regulation of cell-cell adhesion	1.497015e-3
GO:0001667	ameboidal cell migration	1.522075e-3
GO:0051702	interaction with symbiont	1.527940e-3
GO:0060157	urinary bladder development	1.530024e-3
GO:0044403	symbiosis, encompassing mutualism through parasitism	1.538464e-3
GO:0060603	mammary gland duct morphogenesis	1.602169e-3
GO:0043044	ATP-dependent chromatin remodeling	1.612772e-3
GO:0021517	ventral spinal cord development	1.701134e-3
GO:0048640	negative regulation of developmental growth	1.701589e-3
GO:0048762	mesenchymal cell differentiation	1.705250e-3
GO:0043583	ear development	1.744660e-3
GO:0022028	tangential migration from the subventricular zone to the olfactory bulb	1.748397e-3
GO:0008207	C21-steroid hormone metabolic process	1.766952e-3
GO:0071218	cellular response to misfolded protein	1.768225e-3
GO:0034983	peptidyl-lysine deacetylation	1.768225e-3
GO:0090037	positive regulation of protein kinase C signaling cascade	1.775529e-3
GO:0045197	establishment or maintenance of epithelial cell apical/basal polarity	1.796272e-3
GO:0051093	negative regulation of developmental process	1.870080e-3
GO:0001960	negative regulation of cytokine-mediated signaling pathway	1.892281e-3
GO:0002091	negative regulation of receptor internalization	1.894050e-3
GO:0000492	box C/D snoRNP assembly	1.894050e-3
GO:0006301	postreplication repair	1.912689e-3
GO:0003347	epicardial cell to mesenchymal cell transition	1.924494e-3
GO:0006706	steroid catabolic process	1.936781e-3
GO:0030330	DNA damage response, signal transduction by p53 class mediator	1.960476e-3
GO:0051179	localization	1.967097e-3
GO:0014707	branchiomeric skeletal muscle development	1.979097e-3
GO:0046125	pyrimidine deoxyribonucleoside metabolic process	1.979097e-3
GO:0003279	cardiac septum development	1.990679e-3
GO:0042921	glucocorticoid receptor signaling pathway	1.992813e-3
GO:0060174	limb bud formation	1.998375e-3
GO:0061081	positive regulation of myeloid leukocyte cytokine production involved in immune response	1.999270e-3
GO:0060638	mesenchymal-epithelial cell signaling	2.013671e-3
GO:0060828	regulation of canonical Wnt receptor signaling pathway	2.048650e-3
GO:0044419	interspecies interaction between organisms	2.059568e-3
GO:0070201	regulation of establishment of protein localization	2.065958e-3
GO:0031122	cytoplasmic microtubule organization	2.088906e-3
GO:0009225	nucleotide-sugar metabolic process	2.174745e-3
GO:0046007	negative regulation of activated T cell proliferation	2.206726e-3
GO:0032148	activation of protein kinase B activity	2.206879e-3
GO:0010164	response to cesium ion	2.272975e-3
GO:0008582	regulation of synaptic growth at neuromuscular junction	2.272975e-3
GO:0007341	penetration of zona pellucida	2.343186e-3
GO:0050691	regulation of defense response to virus by host	2.376880e-3
GO:0002329	pre-B cell differentiation	2.376880e-3
GO:0009624	response to nematode	2.420315e-3
GO:0009411	response to UV	2.420541e-3
GO:0002244	hemopoietic progenitor cell differentiation	2.423314e-3
GO:0071895	odontoblast differentiation	2.426197e-3
GO:0060368	regulation of Fc receptor mediated stimulatory signaling pathway	2.451766e-3
GO:0033127	regulation of histone phosphorylation	2.451766e-3
GO:0007154	cell communication	2.453818e-3
GO:0008104	protein localization	2.539174e-3
GO:0008283	cell proliferation	2.585633e-3
GO:0002320	lymphoid progenitor cell differentiation	2.603800e-3
GO:0048149	behavioral response to ethanol	2.612736e-3
GO:0060338	regulation of type I interferon-mediated signaling pathway	2.634681e-3
GO:0007223	Wnt receptor signaling pathway, calcium modulating pathway	2.683343e-3
GO:0048683	regulation of collateral sprouting of intact axon in response to injury	2.695644e-3
GO:0010520	regulation of reciprocal meiotic recombination	2.714864e-3
GO:0016101	diterpenoid metabolic process	2.720908e-3
GO:0050909	sensory perception of taste	2.780778e-3
GO:0035270	endocrine system development	2.892649e-3
GO:0048732	gland development	2.968229e-3
GO:0046459	short-chain fatty acid metabolic process	2.996659e-3
GO:0030223	neutrophil differentiation	3.016640e-3
GO:0021915	neural tube development	3.038065e-3
GO:0007156	homophilic cell adhesion	3.084002e-3
GO:0030097	hemopoiesis	3.095548e-3
GO:0071625	vocalization behavior	3.121801e-3
GO:0030825	positive regulation of cGMP metabolic process	3.121801e-3
GO:0043066	negative regulation of apoptosis	3.145347e-3
GO:0048631	regulation of skeletal muscle tissue growth	3.163640e-3
GO:0009161	ribonucleoside monophosphate metabolic process	3.192070e-3
GO:0060686	negative regulation of prostatic bud formation	3.234628e-3
GO:0014741	negative regulation of muscle hypertrophy	3.234628e-3
GO:0044003	modification by symbiont of host morphology or physiology	3.265467e-3
GO:0016331	morphogenesis of embryonic epithelium	3.271293e-3
GO:0046822	regulation of nucleocytoplasmic transport	3.368753e-3
GO:0071346	cellular response to interferon-gamma	3.370005e-3
GO:0048863	stem cell differentiation	3.410373e-3
GO:0010935	regulation of macrophage cytokine production	3.430451e-3
GO:0051967	negative regulation of synaptic transmission, glutamatergic	3.463724e-3
GO:0061153	trachea gland development	3.463724e-3
GO:0051856	adhesion to symbiont	3.463724e-3
GO:0048069	eye pigmentation	3.463724e-3
GO:0051964	negative regulation of synapse assembly	3.463724e-3
GO:0032696	negative regulation of interleukin-13 production	3.481899e-3
GO:0007399	nervous system development	3.501847e-3
GO:0050773	regulation of dendrite development	3.502067e-3
GO:2000401	regulation of lymphocyte migration	3.544105e-3
GO:0030111	regulation of Wnt receptor signaling pathway	3.551343e-3
GO:0006344	maintenance of chromatin silencing	3.618844e-3
GO:0042706	eye photoreceptor cell fate commitment	3.678436e-3
GO:0006083	acetate metabolic process	3.678436e-3
GO:0060947	cardiac vascular smooth muscle cell differentiation	3.707294e-3
GO:0007165	signal transduction	3.807015e-3
GO:0048340	paraxial mesoderm morphogenesis	3.852032e-3
GO:0048341	paraxial mesoderm formation	3.871973e-3
GO:0080135	regulation of cellular response to stress	3.947982e-3
GO:0006085	acetyl-CoA biosynthetic process	3.956479e-3
GO:0051961	negative regulation of nervous system development	3.956479e-3
GO:0042759	long-chain fatty acid biosynthetic process	4.046153e-3
GO:0031575	mitotic cell cycle G1/S transition checkpoint	4.070811e-3
GO:0016055	Wnt receptor signaling pathway	4.073270e-3
GO:2000758	positive regulation of peptidyl-lysine acetylation	4.132739e-3
GO:0071333	cellular response to glucose stimulus	4.175869e-3
GO:0048382	mesendoderm development	4.241402e-3
GO:0002040	sprouting angiogenesis	4.270456e-3
GO:2000045	regulation of G1/S transition of mitotic cell cycle	4.271362e-3
GO:0048814	regulation of dendrite morphogenesis	4.321079e-3
GO:2000059	negative regulation of protein ubiquitination involved in ubiquitin-dependent protein catabolic process	4.323238e-3
GO:0060631	regulation of meiosis I	4.323238e-3
GO:0043482	cellular pigment accumulation	4.323238e-3
GO:0007411	axon guidance	4.471447e-3
GO:0042447	hormone catabolic process	4.475054e-3
GO:0035458	cellular response to interferon-beta	4.516495e-3
GO:0032230	positive regulation of synaptic transmission, GABAergic	4.516495e-3
GO:0033630	positive regulation of cell adhesion mediated by integrin	4.516495e-3
GO:0032387	negative regulation of intracellular transport	4.527128e-3
GO:2000058	regulation of protein ubiquitination involved in ubiquitin-dependent protein catabolic process	4.642252e-3
GO:0032849	positive regulation of cellular pH reduction	4.707751e-3
GO:0010870	positive regulation of receptor biosynthetic process	4.707751e-3
GO:0006515	misfolded or incompletely synthesized protein catabolic process	4.707751e-3
GO:0006333	chromatin assembly or disassembly	4.803636e-3
GO:0002720	positive regulation of cytokine production involved in immune response	4.843913e-3
GO:0060119	inner ear receptor cell development	4.843913e-3
GO:0002481	antigen processing and presentation of exogenous protein antigen via MHC class Ib, TAP-dependent	4.853804e-3
GO:0035088	establishment or maintenance of apical/basal cell polarity	4.867409e-3
GO:0071322	cellular response to carbohydrate stimulus	4.910355e-3
GO:0033157	regulation of intracellular protein transport	4.963674e-3
GO:0034263	autophagy in response to ER overload	4.976687e-3
GO:0030328	prenylcysteine catabolic process	4.976687e-3
GO:0001961	positive regulation of cytokine-mediated signaling pathway	4.987927e-3
GO:0060122	inner ear receptor stereocilium organization	4.990981e-3
GO:0051659	maintenance of mitochondrion location	5.000222e-3
GO:0048172	regulation of short-term neuronal synaptic plasticity	5.088893e-3
GO:0001839	neural plate morphogenesis	5.088893e-3
GO:0060443	mammary gland morphogenesis	5.092269e-3
GO:0043069	negative regulation of programmed cell death	5.113480e-3
GO:0015670	carbon dioxide transport	5.114580e-3
GO:0009812	flavonoid metabolic process	5.114580e-3
GO:0032755	positive regulation of interleukin-6 production	5.187181e-3
GO:0048339	paraxial mesoderm development	5.188133e-3
GO:0033005	positive regulation of mast cell activation	5.236721e-3
GO:0021761	limbic system development	5.329030e-3
GO:0060134	prepulse inhibition	5.425746e-3
GO:0051883	killing of cells in other organism involved in symbiotic interaction	5.425746e-3
GO:0046618	drug export	5.516812e-3
GO:0046503	glycerolipid catabolic process	5.614379e-3
GO:0031640	killing of cells of other organism	5.648405e-3
GO:0001542	ovulation from ovarian follicle	5.699611e-3
GO:0045063	T-helper 1 cell differentiation	5.733441e-3
GO:0042572	retinol metabolic process	5.761384e-3
GO:0006821	chloride transport	5.857677e-3
GO:0006721	terpenoid metabolic process	5.905018e-3
GO:0048513	organ development	5.963507e-3
GO:0051026	chiasma assembly	5.997420e-3
GO:0001838	embryonic epithelial tube formation	6.007993e-3
GO:0060849	regulation of transcription involved in lymphatic endothelial cell fate commitment	6.076355e-3
GO:0050851	antigen receptor-mediated signaling pathway	6.235835e-3
GO:0035050	embryonic heart tube development	6.256821e-3
GO:0060685	regulation of prostatic bud formation	6.323373e-3
GO:0071560	cellular response to transforming growth factor beta stimulus	6.420370e-3
GO:0046825	regulation of protein export from nucleus	6.441080e-3
GO:0050852	T cell receptor signaling pathway	6.468987e-3
GO:0014054	positive regulation of gamma-aminobutyric acid secretion	6.474518e-3
GO:0031100	organ regeneration	6.498590e-3
GO:0071559	response to transforming growth factor beta stimulus	6.532730e-3
GO:0048485	sympathetic nervous system development	6.561208e-3
GO:0048685	negative regulation of collateral sprouting of intact axon in response to injury	6.566182e-3
GO:2001051	positive regulation of tendon cell differentiation	6.566182e-3
GO:0032788	saturated monocarboxylic acid metabolic process	6.566182e-3
GO:0032789	unsaturated monocarboxylic acid metabolic process	6.566182e-3
GO:0021509	roof plate formation	6.566182e-3
GO:0030162	regulation of proteolysis	6.595107e-3
GO:0060760	positive regulation of response to cytokine stimulus	6.618821e-3
GO:0042770	signal transduction in response to DNA damage	6.800217e-3
GO:0060839	endothelial cell fate commitment	6.804942e-3
GO:0006004	fucose metabolic process	6.804942e-3
GO:0072175	epithelial tube formation	6.828819e-3
GO:0090090	negative regulation of canonical Wnt receptor signaling pathway	6.865614e-3
GO:0048843	negative regulation of axon extension involved in axon guidance	6.924149e-3
GO:0003215	cardiac right ventricle morphogenesis	6.931468e-3
GO:0009124	nucleoside monophosphate biosynthetic process	7.026318e-3
GO:0006775	fat-soluble vitamin metabolic process	7.038608e-3
GO:0045184	establishment of protein localization	7.044462e-3
GO:0001678	cellular glucose homeostasis	7.091657e-3
GO:0048584	positive regulation of response to stimulus	7.128760e-3
GO:0032787	monocarboxylic acid metabolic process	7.134825e-3
GO:0006633	fatty acid biosynthetic process	7.165287e-3
GO:0071223	cellular response to lipoteichoic acid	7.191198e-3
GO:0060836	lymphatic endothelial cell differentiation	7.191198e-3
GO:0035308	negative regulation of protein dephosphorylation	7.191198e-3
GO:0001755	neural crest cell migration	7.194157e-3
GO:0050796	regulation of insulin secretion	7.227797e-3
GO:0032714	negative regulation of interleukin-5 production	7.239537e-3
GO:0060562	epithelial tube morphogenesis	7.296822e-3
GO:0015698	inorganic anion transport	7.388393e-3
GO:0061311	cell surface receptor linked signaling pathway involved in heart development	7.403250e-3
GO:0060548	negative regulation of cell death	7.487424e-3
GO:0034501	protein localization to kinetochore	7.502680e-3
GO:0008643	carbohydrate transport	7.528445e-3
GO:0001708	cell fate specification	7.577975e-3
GO:0001947	heart looping	7.652088e-3
GO:0031397	negative regulation of protein ubiquitination	7.669157e-3
GO:0002428	antigen processing and presentation of peptide antigen via MHC class Ib	7.819755e-3
GO:0050849	negative regulation of calcium-mediated signaling	7.819755e-3
GO:0007423	sensory organ development	7.907150e-3
GO:0002831	regulation of response to biotic stimulus	7.914610e-3
GO:0010975	regulation of neuron projection development	7.918061e-3
GO:0043921	modulation by host of viral transcription	7.971411e-3
GO:0060750	epithelial cell proliferation involved in mammary gland duct elongation	8.009072e-3
GO:0001704	formation of primary germ layer	8.015497e-3
GO:0090276	regulation of peptide hormone secretion	8.128869e-3
GO:0043586	tongue development	8.139524e-3
GO:0045936	negative regulation of phosphate metabolic process	8.227704e-3
GO:2000406	positive regulation of T cell migration	8.247873e-3
GO:0032713	negative regulation of interleukin-4 production	8.267237e-3
GO:0048638	regulation of developmental growth	8.342416e-3
GO:0033151	V(D)J recombination	8.450097e-3
GO:0014743	regulation of muscle hypertrophy	8.548761e-3
GO:0007288	sperm axoneme assembly	8.632785e-3
GO:0021766	hippocampus development	8.818338e-3
GO:0021932	hindbrain radial glia guided cell migration	8.973693e-3
GO:0033158	regulation of protein import into nucleus, translocation	9.203170e-3
GO:0009956	radial pattern formation	9.237257e-3
GO:0031345	negative regulation of cell projection organization	9.241275e-3
GO:0022008	neurogenesis	9.275701e-3
GO:0045161	neuronal ion channel clustering	9.353213e-3
GO:0043501	skeletal muscle adaptation	9.353213e-3
GO:0071866	negative regulation of apoptosis in bone marrow	9.353494e-3
GO:0021522	spinal cord motor neuron differentiation	9.450604e-3
GO:0051224	negative regulation of protein transport	9.572578e-3
GO:0060441	epithelial tube branching involved in lung morphogenesis	9.587771e-3
GO:0006610	ribosomal protein import into nucleus	9.625404e-3
GO:0031497	chromatin assembly	9.658510e-3
GO:0009296	flagellum assembly	9.834093e-3
GO:0021515	cell differentiation in spinal cord	9.858898e-3
GO:0051657	maintenance of organelle location	9.868724e-3
GO:0043534	blood vessel endothelial cell migration	9.991918e-3
GO:0015669	gas transport	1.014635e-2
GO:0022904	respiratory electron transport chain	1.016927e-2
GO:0030901	midbrain development	1.028706e-2
GO:0015031	protein transport	1.029343e-2
GO:0043480	pigment accumulation in tissues	1.033365e-2
GO:0032386	regulation of intracellular transport	1.035884e-2