Novel motif:109

name:	motif109_TCNMTMGC

Association to promoter expression in human samples<b>Summary:</b>Significance of the correlation with CAGE expression, human <br><b>Analyst:</b> Michiel de Hoon<br><br>link to source dataset <br>data

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Association to promoter expression in mouse samples <b>Summary:</b>Significance of the correlation with CAGE expression, mouse <br><b>Analyst:</b> Michiel de Hoon<br><br>link to source dataset <br>data

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GREAT analysis results for human <b>Summary:</b>Genomic Enrichment of Annotations Tool (GREAT, Nat Biotechnol. 2010 May;28(5):495-501) is used to identify, both in human and in mouse, the gene ontology terms of biological processes enriched given the predicted TFBSs, and evaluated the overlap in the top-500 gene ontology terms between human and mouse. For each novel motif, the P value for the overlap was then evaluated by calculating its relative rank with respect to this background distribution.<br>Analyst: Michiel de Hoon<br><br>link to source dataset <br>data

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GO ID	GO Term	p-value
GO:0016070	RNA metabolic process	4.242235e-9
GO:0097039	protein linear polyubiquitination	5.252779e-9
GO:0060676	ureteric bud formation	5.981552e-9
GO:0090304	nucleic acid metabolic process	4.403432e-8
GO:0052312	modulation of transcription in other organism involved in symbiotic interaction	1.046645e-7
GO:0070170	regulation of tooth mineralization	1.373464e-7
GO:0031076	embryonic camera-type eye development	1.816160e-7
GO:0016202	regulation of striated muscle tissue development	2.023874e-7
GO:0007096	regulation of exit from mitosis	4.323888e-7
GO:0051252	regulation of RNA metabolic process	4.435947e-7
GO:0021506	anterior neuropore closure	5.721996e-7
GO:0090342	regulation of cell aging	6.756537e-7
GO:0016480	negative regulation of transcription from RNA polymerase III promoter	8.311244e-7
GO:0048706	embryonic skeletal system development	1.075336e-6
GO:0010467	gene expression	1.195512e-6
GO:0060173	limb development	1.224907e-6
GO:0045931	positive regulation of mitotic cell cycle	1.230646e-6
GO:0048634	regulation of muscle organ development	1.245035e-6
GO:0034645	cellular macromolecule biosynthetic process	1.277742e-6
GO:0048704	embryonic skeletal system morphogenesis	1.303932e-6
GO:0000184	nuclear-transcribed mRNA catabolic process, nonsense-mediated decay	1.351436e-6
GO:0032774	RNA biosynthetic process	1.559624e-6
GO:0046884	follicle-stimulating hormone secretion	1.829750e-6
GO:0032275	luteinizing hormone secretion	1.829750e-6
GO:0043921	modulation by host of viral transcription	2.001727e-6
GO:0051253	negative regulation of RNA metabolic process	2.406672e-6
GO:0006355	regulation of transcription, DNA-dependent	2.436035e-6
GO:0002689	negative regulation of leukocyte chemotaxis	2.900393e-6
GO:0045892	negative regulation of transcription, DNA-dependent	3.383004e-6
GO:0090035	positive regulation of cellular chaperone-mediated protein complex assembly	3.458260e-6
GO:0006139	nucleobase-containing compound metabolic process	3.463122e-6
GO:0003409	optic cup structural organization	3.750403e-6
GO:0021623	oculomotor nerve formation	3.750403e-6
GO:0003404	optic vesicle morphogenesis	3.750403e-6
GO:0009059	macromolecule biosynthetic process	3.756155e-6
GO:2000113	negative regulation of cellular macromolecule biosynthetic process	4.754839e-6
GO:0001657	ureteric bud development	4.853739e-6
GO:0006351	transcription, DNA-dependent	5.462604e-6
GO:0046782	regulation of viral transcription	5.996394e-6
GO:0010991	negative regulation of SMAD protein complex assembly	7.467340e-6
GO:0010944	negative regulation of transcription by competitive promoter binding	7.479162e-6
GO:0045934	negative regulation of nucleobase-containing compound metabolic process	7.642547e-6
GO:0045843	negative regulation of striated muscle tissue development	7.725970e-6
GO:0048048	embryonic eye morphogenesis	1.034357e-5
GO:0048596	embryonic camera-type eye morphogenesis	1.151550e-5
GO:0060576	intestinal epithelial cell development	1.157337e-5
GO:2000378	negative regulation of reactive oxygen species metabolic process	1.186293e-5
GO:0061302	smooth muscle cell-matrix adhesion	1.338922e-5
GO:0051702	interaction with symbiont	1.446065e-5
GO:0043922	negative regulation by host of viral transcription	1.474126e-5
GO:0006268	DNA unwinding involved in replication	1.604729e-5
GO:0010468	regulation of gene expression	1.959631e-5
GO:0016570	histone modification	1.994426e-5
GO:0010717	regulation of epithelial to mesenchymal transition	2.002637e-5
GO:0071281	cellular response to iron ion	2.053310e-5
GO:0008033	tRNA processing	2.102112e-5
GO:0009081	branched chain family amino acid metabolic process	2.293652e-5
GO:0019509	L-methionine salvage from methylthioadenosine	2.487607e-5
GO:0034660	ncRNA metabolic process	2.503540e-5
GO:0009790	embryo development	2.597458e-5
GO:0034470	ncRNA processing	2.672413e-5
GO:0010159	specification of organ position	2.765300e-5
GO:0032274	gonadotropin secretion	2.791932e-5
GO:0060764	cell-cell signaling involved in mammary gland development	2.854428e-5
GO:0071934	thiamine transmembrane transport	2.951015e-5
GO:0051172	negative regulation of nitrogen compound metabolic process	2.986442e-5
GO:0023035	CD40 signaling pathway	3.359944e-5
GO:0045081	negative regulation of interleukin-10 biosynthetic process	3.601889e-5
GO:0009083	branched chain family amino acid catabolic process	3.634590e-5
GO:0000279	M phase	3.772346e-5
GO:0072009	nephron epithelium development	4.068211e-5
GO:0006427	histidyl-tRNA aminoacylation	4.086610e-5
GO:0070933	histone H4 deacetylation	4.449908e-5
GO:0048705	skeletal system morphogenesis	4.627427e-5
GO:0042694	muscle cell fate specification	4.884919e-5
GO:0021603	cranial nerve formation	5.058762e-5
GO:0051851	modification by host of symbiont morphology or physiology	5.288346e-5
GO:2000112	regulation of cellular macromolecule biosynthetic process	5.640926e-5
GO:0034983	peptidyl-lysine deacetylation	5.706396e-5
GO:0016569	covalent chromatin modification	5.903776e-5
GO:0006534	cysteine metabolic process	6.032485e-5
GO:0090189	regulation of branching involved in ureteric bud morphogenesis	6.137055e-5
GO:0072087	renal vesicle development	6.373982e-5
GO:0001838	embryonic epithelial tube formation	6.484163e-5
GO:0072070	loop of Henle development	6.751815e-5
GO:0010629	negative regulation of gene expression	7.079017e-5
GO:0017055	negative regulation of RNA polymerase II transcriptional preinitiation complex assembly	7.273973e-5
GO:0007174	epidermal growth factor catabolic process	7.273973e-5
GO:0010070	zygote asymmetric cell division	7.290388e-5
GO:0042696	menarche	7.614660e-5
GO:0016331	morphogenesis of embryonic epithelium	7.863766e-5
GO:0035108	limb morphogenesis	8.047020e-5
GO:0072283	metanephric renal vesicle morphogenesis	8.538747e-5
GO:0009792	embryo development ending in birth or egg hatching	8.644881e-5
GO:0070306	lens fiber cell differentiation	8.733840e-5
GO:0032543	mitochondrial translation	8.770538e-5
GO:0042891	antibiotic transport	9.250680e-5
GO:0030579	ubiquitin-dependent SMAD protein catabolic process	9.250680e-5
GO:0021778	oligodendrocyte cell fate specification	9.488329e-5
GO:0030326	embryonic limb morphogenesis	9.685697e-5
GO:0002003	angiotensin maturation	1.121990e-4
GO:0070172	positive regulation of tooth mineralization	1.128074e-4
GO:0072073	kidney epithelium development	1.129905e-4
GO:0072077	renal vesicle morphogenesis	1.204768e-4
GO:0001656	metanephros development	1.265222e-4
GO:0031327	negative regulation of cellular biosynthetic process	1.290771e-4
GO:0010558	negative regulation of macromolecule biosynthetic process	1.313916e-4
GO:0072088	nephron epithelium morphogenesis	1.370632e-4
GO:0072272	proximal/distal pattern formation involved in metanephric nephron development	1.447571e-4
GO:0043009	chordate embryonic development	1.503976e-4
GO:0070309	lens fiber cell morphogenesis	1.575631e-4
GO:0035115	embryonic forelimb morphogenesis	1.602852e-4
GO:0021798	forebrain dorsal/ventral pattern formation	1.732538e-4
GO:0018205	peptidyl-lysine modification	1.758147e-4
GO:0032897	negative regulation of viral transcription	1.778349e-4
GO:0050434	positive regulation of viral transcription	1.856269e-4
GO:0007141	male meiosis I	1.879238e-4
GO:0072175	epithelial tube formation	1.916838e-4
GO:0001302	replicative cell aging	1.942545e-4
GO:2000648	positive regulation of stem cell proliferation	1.995963e-4
GO:0070932	histone H3 deacetylation	2.047907e-4
GO:0044260	cellular macromolecule metabolic process	2.120110e-4
GO:0072268	pattern specification involved in metanephros development	2.150942e-4
GO:0090190	positive regulation of branching involved in ureteric bud morphogenesis	2.155447e-4
GO:0003337	mesenchymal to epithelial transition involved in metanephros morphogenesis	2.179565e-4
GO:0060371	regulation of atrial cardiomyocyte membrane depolarization	2.181222e-4
GO:0031860	telomeric 3' overhang formation	2.181222e-4
GO:0021512	spinal cord anterior/posterior patterning	2.181222e-4
GO:0000096	sulfur amino acid metabolic process	2.198919e-4
GO:0006646	phosphatidylethanolamine biosynthetic process	2.319511e-4
GO:0002064	epithelial cell development	2.349668e-4
GO:0070193	synaptonemal complex organization	2.379641e-4
GO:0035461	vitamin transmembrane transport	2.468206e-4
GO:0016598	protein arginylation	2.556941e-4
GO:0006368	transcription elongation from RNA polymerase II promoter	2.570270e-4
GO:0007129	synapsis	2.643498e-4
GO:0048635	negative regulation of muscle organ development	2.713182e-4
GO:0048103	somatic stem cell division	2.774937e-4
GO:0021779	oligodendrocyte cell fate commitment	2.882282e-4
GO:0048598	embryonic morphogenesis	2.961355e-4
GO:0090183	regulation of kidney development	2.996844e-4
GO:0060900	embryonic camera-type eye formation	3.012744e-4
GO:0006399	tRNA metabolic process	3.058206e-4
GO:0035621	ER to Golgi ceramide transport	3.077248e-4
GO:0010477	response to sulfur dioxide	3.077248e-4
GO:0043181	vacuolar sequestering	3.077248e-4
GO:0000023	maltose metabolic process	3.077248e-4
GO:0002457	T cell antigen processing and presentation	3.077248e-4
GO:0005985	sucrose metabolic process	3.077248e-4
GO:0051488	activation of anaphase-promoting complex activity	3.096528e-4
GO:2000683	regulation of cellular response to X-ray	3.162834e-4
GO:0033083	regulation of immature T cell proliferation	3.170829e-4
GO:0070831	basement membrane assembly	3.171393e-4
GO:0007379	segment specification	3.174023e-4
GO:0048332	mesoderm morphogenesis	3.251618e-4
GO:0090402	oncogene-induced senescence	3.272702e-4
GO:0031326	regulation of cellular biosynthetic process	3.336641e-4
GO:0002072	optic cup morphogenesis involved in camera-type eye development	3.380159e-4
GO:0060993	kidney morphogenesis	3.551415e-4
GO:0010172	embryonic body morphogenesis	3.679437e-4
GO:0032049	cardiolipin biosynthetic process	3.695009e-4
GO:0019219	regulation of nucleobase-containing compound metabolic process	3.748375e-4
GO:0003310	pancreatic A cell differentiation	3.841666e-4
GO:0045762	positive regulation of adenylate cyclase activity	3.868235e-4
GO:0009451	RNA modification	3.881303e-4
GO:0007190	activation of adenylate cyclase activity	3.891137e-4
GO:0031324	negative regulation of cellular metabolic process	4.036348e-4
GO:0060231	mesenchymal to epithelial transition	4.088712e-4
GO:0009452	RNA capping	4.317065e-4
GO:0006284	base-excision repair	4.382717e-4
GO:0009890	negative regulation of biosynthetic process	4.388539e-4
GO:0060043	regulation of cardiac muscle cell proliferation	4.483696e-4
GO:0051365	cellular response to potassium ion starvation	4.572137e-4
GO:0072028	nephron morphogenesis	4.716059e-4
GO:0033091	positive regulation of immature T cell proliferation	4.757629e-4
GO:0031281	positive regulation of cyclase activity	5.340072e-4
GO:0030514	negative regulation of BMP signaling pathway	5.482561e-4
GO:0003420	regulation of growth plate cartilage chondrocyte proliferation	5.511276e-4
GO:0035136	forelimb morphogenesis	5.530298e-4
GO:0048642	negative regulation of skeletal muscle tissue development	5.556359e-4
GO:0090101	negative regulation of transmembrane receptor protein serine/threonine kinase signaling pathway	5.571935e-4
GO:0046092	deoxycytidine metabolic process	5.902796e-4
GO:0031468	nuclear envelope reassembly	5.902796e-4
GO:0060045	positive regulation of cardiac muscle cell proliferation	5.904308e-4
GO:0003208	cardiac ventricle morphogenesis	6.017535e-4
GO:0051171	regulation of nitrogen compound metabolic process	6.029826e-4
GO:0006413	translational initiation	6.264400e-4
GO:0000072	M phase specific microtubule process	6.452144e-4
GO:0010556	regulation of macromolecule biosynthetic process	6.536938e-4
GO:0002686	negative regulation of leukocyte migration	6.604936e-4
GO:0031619	homologous chromosome orientation involved in meiotic metaphase I plate congression	6.794290e-4
GO:0050821	protein stabilization	6.915875e-4
GO:0072081	specification of nephron tubule identity	6.983147e-4
GO:0002121	inter-male aggressive behavior	7.012326e-4
GO:0090003	regulation of establishment of protein localization in plasma membrane	7.062178e-4
GO:0043923	positive regulation by host of viral transcription	7.125458e-4
GO:0070192	chromosome organization involved in meiosis	7.170746e-4
GO:0007127	meiosis I	7.239627e-4
GO:0006348	chromatin silencing at telomere	7.545203e-4
GO:0035148	tube formation	7.987105e-4
GO:0060574	intestinal epithelial cell maturation	8.099138e-4
GO:0048313	Golgi inheritance	8.173063e-4
GO:0033147	negative regulation of estrogen receptor signaling pathway	8.435827e-4
GO:2000677	regulation of transcription regulatory region DNA binding	8.583793e-4
GO:0035304	regulation of protein dephosphorylation	8.628113e-4
GO:0061004	pattern specification involved in kidney development	8.676464e-4
GO:0070544	histone H3-K36 demethylation	8.744843e-4
GO:0006595	polyamine metabolic process	8.745492e-4
GO:0072091	regulation of stem cell proliferation	8.933799e-4
GO:0048524	positive regulation of viral reproduction	9.220310e-4
GO:0048641	regulation of skeletal muscle tissue development	9.272643e-4
GO:0030520	estrogen receptor signaling pathway	9.638627e-4
GO:0002011	morphogenesis of an epithelial sheet	9.844801e-4
GO:0033600	negative regulation of mammary gland epithelial cell proliferation	1.012056e-3
GO:0060739	mesenchymal-epithelial cell signaling involved in prostate gland development	1.025987e-3
GO:0006855	drug transmembrane transport	1.047263e-3
GO:0021915	neural tube development	1.059499e-3
GO:0090141	positive regulation of mitochondrial fission	1.077821e-3
GO:0051349	positive regulation of lyase activity	1.092530e-3
GO:0007212	dopamine receptor signaling pathway	1.101767e-3
GO:0000959	mitochondrial RNA metabolic process	1.103717e-3
GO:0017145	stem cell division	1.115259e-3
GO:0000956	nuclear-transcribed mRNA catabolic process	1.120313e-3
GO:0001941	postsynaptic membrane organization	1.120896e-3
GO:0034641	cellular nitrogen compound metabolic process	1.131507e-3
GO:0007189	activation of adenylate cyclase activity by G-protein signaling pathway	1.154581e-3
GO:0048690	regulation of axon extension involved in regeneration	1.178605e-3
GO:0018283	iron incorporation into metallo-sulfur cluster	1.178605e-3
GO:0010605	negative regulation of macromolecule metabolic process	1.220259e-3
GO:0031662	positive regulation of cyclin-dependent protein kinase activity involved in G2/M	1.221227e-3
GO:0070194	synaptonemal complex disassembly	1.221227e-3
GO:0001522	pseudouridine synthesis	1.221510e-3
GO:0072086	specification of loop of Henle identity	1.244525e-3
GO:0018350	protein esterification	1.244525e-3
GO:0044258	intestinal lipid catabolic process	1.244525e-3
GO:0072179	nephric duct formation	1.256397e-3
GO:0035860	glial cell-derived neurotrophic factor receptor signaling pathway	1.280565e-3
GO:0015893	drug transport	1.306676e-3
GO:0006396	RNA processing	1.307358e-3
GO:2000772	regulation of cellular senescence	1.318883e-3
GO:0000122	negative regulation of transcription from RNA polymerase II promoter	1.334025e-3
GO:0031658	negative regulation of cyclin-dependent protein kinase activity involved in G1/S	1.373947e-3
GO:0035364	thymine transport	1.373947e-3
GO:0051315	attachment of spindle microtubules to kinetochore involved in mitotic sister chromatid segregation	1.373947e-3
GO:0035344	hypoxanthine transport	1.373947e-3
GO:0015854	guanine transport	1.373947e-3
GO:0007092	activation of mitotic anaphase-promoting complex activity	1.373947e-3
GO:0010836	negative regulation of protein ADP-ribosylation	1.373947e-3
GO:0021532	neural tube patterning	1.376727e-3
GO:0072285	mesenchymal to epithelial transition involved in metanephric renal vesicle formation	1.378561e-3
GO:0060830	ciliary receptor clustering involved in smoothened signaling pathway	1.378561e-3
GO:0007371	ventral midline determination	1.378561e-3
GO:0060248	detection of cell density by contact stimulus involved in contact inhibition	1.378561e-3
GO:0060435	bronchiole development	1.404877e-3
GO:0021877	forebrain neuron fate commitment	1.425067e-3
GO:0045074	regulation of interleukin-10 biosynthetic process	1.426839e-3
GO:0021903	rostrocaudal neural tube patterning	1.438579e-3
GO:0031507	heterochromatin formation	1.441757e-3
GO:0060480	lung goblet cell differentiation	1.445259e-3
GO:0003338	metanephros morphogenesis	1.501389e-3
GO:0045136	development of secondary sexual characteristics	1.504675e-3
GO:0032808	lacrimal gland development	1.519221e-3
GO:0061351	neural precursor cell proliferation	1.531549e-3
GO:0072333	signal transduction by p53 class mediator resulting in induction of anoikis	1.558015e-3
GO:0050883	musculoskeletal movement, spinal reflex action	1.613186e-3
GO:0031591	wybutosine biosynthetic process	1.613186e-3
GO:0006844	acyl carnitine transport	1.613186e-3
GO:0003229	ventricular cardiac muscle tissue development	1.659305e-3
GO:0040009	regulation of growth rate	1.660792e-3
GO:0021535	cell migration in hindbrain	1.678556e-3
GO:0072210	metanephric nephron development	1.693010e-3
GO:0048340	paraxial mesoderm morphogenesis	1.694162e-3
GO:0055021	regulation of cardiac muscle tissue growth	1.730475e-3
GO:0003081	regulation of systemic arterial blood pressure by renin-angiotensin	1.751801e-3
GO:0070173	regulation of enamel mineralization	1.771862e-3
GO:0048663	neuron fate commitment	1.794930e-3
GO:0009889	regulation of biosynthetic process	1.814696e-3
GO:0021510	spinal cord development	1.815679e-3
GO:0035117	embryonic arm morphogenesis	1.828564e-3
GO:0051660	establishment of centrosome localization	1.834310e-3
GO:0071335	hair follicle cell proliferation	1.834310e-3
GO:0032290	peripheral nervous system myelin formation	1.834310e-3
GO:0021540	corpus callosum morphogenesis	1.834310e-3
GO:0055117	regulation of cardiac muscle contraction	1.849815e-3
GO:0050435	beta-amyloid metabolic process	1.869743e-3
GO:0040015	negative regulation of multicellular organism growth	1.869743e-3
GO:0021759	globus pallidus development	1.901839e-3
GO:0090049	regulation of cell migration involved in sprouting angiogenesis	1.939335e-3
GO:0045900	negative regulation of translational elongation	1.940997e-3
GO:0032066	nucleolus to nucleoplasm transport	1.940997e-3
GO:0035507	regulation of myosin-light-chain-phosphatase activity	1.951124e-3
GO:0060282	positive regulation of oocyte development	1.958080e-3
GO:0003180	aortic valve morphogenesis	2.022022e-3
GO:0048562	embryonic organ morphogenesis	2.064511e-3
GO:0002076	osteoblast development	2.121276e-3
GO:0008635	activation of caspase activity by cytochrome c	2.153692e-3
GO:0030262	apoptotic nuclear change	2.166429e-3
GO:0010719	negative regulation of epithelial to mesenchymal transition	2.169409e-3
GO:0048341	paraxial mesoderm formation	2.176188e-3
GO:0030423	targeting of mRNA for destruction involved in RNA interference	2.231720e-3
GO:0048754	branching morphogenesis of a tube	2.289983e-3
GO:0034442	regulation of lipoprotein oxidation	2.307325e-3
GO:0040040	thermosensory behavior	2.331633e-3
GO:0032792	negative regulation of CREB transcription factor activity	2.371750e-3
GO:0071224	cellular response to peptidoglycan	2.382456e-3
GO:0021516	dorsal spinal cord development	2.422645e-3
GO:0034971	histone H3-R17 methylation	2.440168e-3
GO:0000088	mitotic prophase	2.440168e-3
GO:0050928	negative regulation of positive chemotaxis	2.504302e-3
GO:0070307	lens fiber cell development	2.510664e-3
GO:0003334	keratinocyte development	2.560696e-3
GO:0021918	regulation of transcription from RNA polymerase II promoter involved in somatic motor neuron fate commitment	2.566534e-3
GO:0021905	forebrain-midbrain boundary formation	2.566534e-3
GO:0003322	pancreatic A cell development	2.566534e-3
GO:0021902	commitment of neuronal cell to specific neuron type in forebrain	2.566534e-3
GO:0048593	camera-type eye morphogenesis	2.598897e-3
GO:0003016	respiratory system process	2.612445e-3
GO:0016577	histone demethylation	2.687984e-3
GO:0060482	lobar bronchus development	2.695032e-3
GO:0003360	brainstem development	2.704469e-3
GO:0034699	response to luteinizing hormone stimulus	2.735757e-3
GO:0042998	positive regulation of Golgi to plasma membrane protein transport	2.735757e-3
GO:0070534	protein K63-linked ubiquitination	2.797080e-3
GO:0003382	epithelial cell morphogenesis	2.887013e-3
GO:0009954	proximal/distal pattern formation	2.912653e-3
GO:0006551	leucine metabolic process	2.947569e-3
GO:0006807	nitrogen compound metabolic process	2.956419e-3
GO:0090140	regulation of mitochondrial fission	2.958818e-3
GO:0032968	positive regulation of transcription elongation from RNA polymerase II promoter	2.958818e-3
GO:0002066	columnar/cuboidal epithelial cell development	2.988293e-3
GO:0032790	ribosome disassembly	3.005960e-3
GO:0090344	negative regulation of cell aging	3.035490e-3
GO:0035239	tube morphogenesis	3.057496e-3
GO:0007249	I-kappaB kinase/NF-kappaB cascade	3.074128e-3
GO:0006370	mRNA capping	3.114255e-3
GO:0007195	inhibition of adenylate cyclase activity by dopamine receptor signaling pathway	3.128340e-3
GO:0033084	regulation of immature T cell proliferation in thymus	3.214479e-3
GO:0051447	negative regulation of meiotic cell cycle	3.233244e-3
GO:0002009	morphogenesis of an epithelium	3.300928e-3
GO:0043353	enucleate erythrocyte differentiation	3.316193e-3
GO:0051096	positive regulation of helicase activity	3.355032e-3
GO:0006401	RNA catabolic process	3.381826e-3
GO:0048285	organelle fission	3.416299e-3
GO:0071166	ribonucleoprotein complex localization	3.457395e-3
GO:0035356	cellular triglyceride homeostasis	3.457395e-3
GO:0072273	metanephric nephron morphogenesis	3.466069e-3
GO:0008630	DNA damage response, signal transduction resulting in induction of apoptosis	3.473271e-3
GO:0009067	aspartate family amino acid biosynthetic process	3.498230e-3
GO:0072006	nephron development	3.517833e-3
GO:0034616	response to laminar fluid shear stress	3.523912e-3
GO:0090050	positive regulation of cell migration involved in sprouting angiogenesis	3.524961e-3
GO:0060046	regulation of acrosome reaction	3.603054e-3
GO:0009086	methionine biosynthetic process	3.697373e-3
GO:0043456	regulation of pentose-phosphate shunt	3.699437e-3
GO:0018872	arsonoacetate metabolic process	3.699437e-3
GO:0007113	endomitotic cell cycle	3.699437e-3
GO:0006425	glutaminyl-tRNA aminoacylation	3.699437e-3
GO:0046514	ceramide catabolic process	3.758113e-3
GO:0000097	sulfur amino acid biosynthetic process	3.767226e-3
GO:2000124	regulation of endocannabinoid signaling pathway	3.784665e-3
GO:0072017	distal tubule development	3.805144e-3
GO:0030302	deoxynucleotide transport	3.865801e-3
GO:0002380	immunoglobulin secretion involved in immune response	3.865801e-3
GO:0072332	signal transduction by p53 class mediator resulting in induction of apoptosis	3.931983e-3
GO:0007140	male meiosis	3.935633e-3
GO:0001544	initiation of primordial ovarian follicle growth	3.979866e-3
GO:0007492	endoderm development	4.017839e-3
GO:0090281	negative regulation of calcium ion import	4.025788e-3
GO:0071584	negative regulation of zinc ion import	4.025788e-3
GO:0000073	spindle pole body separation	4.025788e-3
GO:0031627	telomeric loop formation	4.025788e-3
GO:0022904	respiratory electron transport chain	4.104260e-3
GO:0071167	ribonucleoprotein complex import into nucleus	4.122622e-3
GO:0051083	'de novo' cotranslational protein folding	4.122622e-3
GO:0061303	cornea development in camera-type eye	4.176926e-3
GO:2000774	positive regulation of cellular senescence	4.235412e-3
GO:0035986	senescence-associated heterochromatin focus formation	4.235412e-3
GO:0042770	signal transduction in response to DNA damage	4.338866e-3
GO:0032239	regulation of nucleobase-containing compound transport	4.339611e-3
GO:0001763	morphogenesis of a branching structure	4.371999e-3
GO:0043113	receptor clustering	4.415695e-3
GO:2000736	regulation of stem cell differentiation	4.425547e-3
GO:0000710	meiotic mismatch repair	4.454218e-3
GO:0072133	metanephric mesenchyme morphogenesis	4.454218e-3
GO:0009798	axis specification	4.473131e-3
GO:0060004	reflex	4.484597e-3
GO:0003002	regionalization	4.539177e-3
GO:0001501	skeletal system development	4.611149e-3
GO:0060060	post-embryonic retina morphogenesis in camera-type eye	4.673296e-3
GO:0060580	ventral spinal cord interneuron fate determination	4.673296e-3
GO:0015734	taurine transport	4.673296e-3
GO:0003327	type B pancreatic cell fate commitment	4.673296e-3
GO:0070681	glutaminyl-tRNAGln biosynthesis via transamidation	4.868593e-3
GO:0090303	positive regulation of wound healing	4.907989e-3
GO:2000369	regulation of clathrin-mediated endocytosis	4.981478e-3
GO:0015884	folic acid transport	5.081816e-3
GO:0048701	embryonic cranial skeleton morphogenesis	5.106795e-3
GO:0034508	centromere complex assembly	5.119385e-3
GO:0045750	positive regulation of S phase of mitotic cell cycle	5.213448e-3
GO:0031536	positive regulation of exit from mitosis	5.228166e-3
GO:0060534	trachea cartilage development	5.238368e-3
GO:2000679	positive regulation of transcription regulatory region DNA binding	5.244036e-3
GO:0046113	nucleobase catabolic process	5.337366e-3
GO:0061386	closure of optic fissure	5.376986e-3
GO:0048936	peripheral nervous system neuron axonogenesis	5.376986e-3
GO:0019056	modulation by virus of host transcription	5.376986e-3
GO:0035332	positive regulation of hippo signaling cascade	5.376986e-3
GO:0048691	positive regulation of axon extension involved in regeneration	5.376986e-3
GO:0007067	mitosis	5.388488e-3
GO:0003206	cardiac chamber morphogenesis	5.401610e-3
GO:0000415	negative regulation of histone H3-K36 methylation	5.403422e-3
GO:2000696	regulation of epithelial cell differentiation involved in kidney development	5.498371e-3
GO:0010957	negative regulation of vitamin D biosynthetic process	5.522345e-3
GO:0022403	cell cycle phase	5.564629e-3
GO:0051642	centrosome localization	5.643141e-3
GO:0033962	cytoplasmic mRNA processing body assembly	5.647023e-3
GO:0033092	positive regulation of immature T cell proliferation in thymus	5.651690e-3
GO:0090004	positive regulation of establishment of protein localization in plasma membrane	5.742633e-3
GO:0022004	midbrain-hindbrain boundary maturation during brain development	5.762947e-3
GO:0090168	Golgi reassembly	5.762947e-3
GO:0021588	cerebellum formation	5.762947e-3
GO:2000002	negative regulation of DNA damage checkpoint	5.762947e-3
GO:0003106	negative regulation of glomerular filtration by angiotensin	5.762947e-3
GO:0014895	smooth muscle hypertrophy	5.762947e-3
GO:0021551	central nervous system morphogenesis	5.762947e-3
GO:0030641	regulation of cellular pH	5.865267e-3
GO:0060562	epithelial tube morphogenesis	5.865854e-3
GO:0060485	mesenchyme development	5.885687e-3
GO:2000210	positive regulation of anoikis	6.080248e-3
GO:2000685	positive regulation of cellular response to X-ray	6.080248e-3
GO:2001033	negative regulation of double-strand break repair via nonhomologous end joining	6.080248e-3
GO:2001038	regulation of cellular response to drug	6.080248e-3
GO:0046125	pyrimidine deoxyribonucleoside metabolic process	6.080248e-3
GO:0003131	mesodermal-endodermal cell signaling	6.080248e-3
GO:0031052	chromosome breakage	6.080248e-3
GO:0035978	histone H2A-S139 phosphorylation	6.080248e-3
GO:0051153	regulation of striated muscle cell differentiation	6.094021e-3
GO:0009892	negative regulation of metabolic process	6.175189e-3
GO:0006482	protein demethylation	6.196385e-3
GO:0008272	sulfate transport	6.231831e-3
GO:0010025	wax biosynthetic process	6.261006e-3
GO:0046607	positive regulation of centrosome cycle	6.261006e-3
GO:0009822	alkaloid catabolic process	6.261006e-3
GO:0060054	positive regulation of epithelial cell proliferation involved in wound healing	6.287700e-3
GO:0035264	multicellular organism growth	6.401521e-3
GO:0055024	regulation of cardiac muscle tissue development	6.421901e-3
GO:0019087	transformation of host cell by virus	6.455242e-3
GO:0021879	forebrain neuron differentiation	6.493493e-3
GO:0060174	limb bud formation	6.500818e-3
GO:0065001	specification of axis polarity	6.518444e-3
GO:0045333	cellular respiration	6.612159e-3
GO:0045747	positive regulation of Notch signaling pathway	6.641805e-3
GO:0048149	behavioral response to ethanol	6.651907e-3
GO:0010956	negative regulation of calcidiol 1-monooxygenase activity	6.651907e-3
GO:0072178	nephric duct morphogenesis	6.657626e-3
GO:0035026	leading edge cell differentiation	6.662197e-3
GO:0034445	negative regulation of plasma lipoprotein particle oxidation	6.662197e-3
GO:0000578	embryonic axis specification	6.691692e-3
GO:0022027	interkinetic nuclear migration	6.775919e-3
GO:0045604	regulation of epidermal cell differentiation	6.853447e-3
GO:0070127	tRNA aminoacylation for mitochondrial protein translation	6.860057e-3
GO:0006552	leucine catabolic process	6.860057e-3
GO:0060675	ureteric bud morphogenesis	6.886517e-3
GO:0005984	disaccharide metabolic process	6.928712e-3
GO:0043393	regulation of protein binding	6.985345e-3
GO:0006390	transcription from mitochondrial promoter	7.058941e-3
GO:0042593	glucose homeostasis	7.186864e-3
GO:0060420	regulation of heart growth	7.236727e-3
GO:0003215	cardiac right ventricle morphogenesis	7.330579e-3
GO:0051444	negative regulation of ubiquitin-protein ligase activity	7.361472e-3
GO:0009880	embryonic pattern specification	7.489802e-3
GO:0010803	regulation of tumor necrosis factor-mediated signaling pathway	7.535233e-3
GO:0010894	negative regulation of steroid biosynthetic process	7.554209e-3
GO:0045212	neurotransmitter receptor biosynthetic process	7.726115e-3
GO:0006713	glucocorticoid catabolic process	7.726115e-3
GO:0032223	negative regulation of synaptic transmission, cholinergic	7.726115e-3
GO:0060644	mammary gland epithelial cell differentiation	7.729988e-3
GO:0000731	DNA synthesis involved in DNA repair	7.782837e-3
GO:2000036	regulation of stem cell maintenance	7.785086e-3
GO:0010822	positive regulation of mitochondrion organization	7.785086e-3
GO:0070715	sodium-dependent organic cation transport	7.786883e-3
GO:0052106	quorum sensing involved in interaction with host	7.786883e-3
GO:0060731	positive regulation of intestinal epithelial structure maintenance	7.786883e-3
GO:0006119	oxidative phosphorylation	8.022093e-3
GO:0048742	regulation of skeletal muscle fiber development	8.042771e-3
GO:0072331	signal transduction by p53 class mediator	8.079321e-3
GO:0060711	labyrinthine layer development	8.087007e-3
GO:0071895	odontoblast differentiation	8.161196e-3
GO:0035385	Roundabout signaling pathway	8.161196e-3
GO:0002052	positive regulation of neuroblast proliferation	8.234574e-3
GO:0006903	vesicle targeting	8.243086e-3
GO:0072236	metanephric loop of Henle development	8.263263e-3
GO:0060281	regulation of oocyte development	8.263263e-3
GO:0051438	regulation of ubiquitin-protein ligase activity	8.362550e-3
GO:2000824	negative regulation of androgen receptor activity	8.384238e-3
GO:0018230	peptidyl-L-cysteine S-palmitoylation	8.384238e-3
GO:0072240	metanephric DCT cell differentiation	8.394620e-3
GO:0072227	metanephric macula densa development	8.394620e-3
GO:0048561	establishment of organ orientation	8.401431e-3
GO:0032241	positive regulation of nucleobase-containing compound transport	8.401431e-3

GREAT analysis results for mouseGenomic Enrichment of Annotations Tool (GREAT, Nat Biotechnol. 2010 May;28(5):495-501) is used to identify, both in human and in mouse, the gene ontology terms of biological processes enriched given the predicted TFBSs, and evaluated the overlap in the top-500 gene ontology terms between human and mouse. For each novel motif, the P value for the overlap was then evaluated by calculating its relative rank with respect to this background distribution.<br>Analyst: Michiel de Hoon <br><br>link to source dataset <br>data

---

GO ID	GO Term	p-value
GO:0008635	activation of caspase activity by cytochrome c	5.349733e-9
GO:0007067	mitosis	7.802759e-9
GO:0000087	M phase of mitotic cell cycle	9.290048e-9
GO:0035305	negative regulation of dephosphorylation	2.548970e-8
GO:0048285	organelle fission	1.012029e-7
GO:0000278	mitotic cell cycle	1.466732e-7
GO:0022402	cell cycle process	4.345079e-7
GO:0006540	glutamate decarboxylation to succinate	6.471164e-7
GO:0035307	positive regulation of protein dephosphorylation	9.797550e-7
GO:0035304	regulation of protein dephosphorylation	1.067267e-6
GO:0035306	positive regulation of dephosphorylation	1.254053e-6
GO:0017158	regulation of calcium ion-dependent exocytosis	1.438147e-6
GO:0071169	establishment of protein localization to chromatin	1.924786e-6
GO:0006513	protein monoubiquitination	2.070558e-6
GO:0000279	M phase	2.684313e-6
GO:0045647	negative regulation of erythrocyte differentiation	3.001955e-6
GO:0035308	negative regulation of protein dephosphorylation	3.396598e-6
GO:0022403	cell cycle phase	4.068966e-6
GO:0034660	ncRNA metabolic process	1.062544e-5
GO:0060046	regulation of acrosome reaction	1.162798e-5
GO:0006268	DNA unwinding involved in replication	1.170770e-5
GO:0051204	protein insertion into mitochondrial membrane	1.184219e-5
GO:0071394	cellular response to testosterone stimulus	1.199402e-5
GO:0002352	B cell negative selection	1.199402e-5
GO:0046604	positive regulation of mitotic centrosome separation	1.261716e-5
GO:0061013	regulation of mRNA catabolic process	1.315594e-5
GO:0042998	positive regulation of Golgi to plasma membrane protein transport	1.334296e-5
GO:0017196	N-terminal peptidyl-methionine acetylation	1.334296e-5
GO:0032119	sequestering of zinc ion	1.455620e-5
GO:0051238	sequestering of metal ion	1.469665e-5
GO:0033169	histone H3-K9 demethylation	1.594081e-5
GO:0090102	cochlea development	1.832828e-5
GO:0046929	negative regulation of neurotransmitter secretion	2.270722e-5
GO:0003050	regulation of systemic arterial blood pressure by atrial natriuretic peptide	2.270722e-5
GO:0034441	plasma lipoprotein particle oxidation	2.270722e-5
GO:0046092	deoxycytidine metabolic process	2.373397e-5
GO:0070076	histone lysine demethylation	2.630099e-5
GO:0035329	hippo signaling cascade	2.678960e-5
GO:0001844	protein insertion into mitochondrial membrane involved in induction of apoptosis	2.905373e-5
GO:0060048	cardiac muscle contraction	2.996615e-5
GO:0060574	intestinal epithelial cell maturation	3.132049e-5
GO:0001510	RNA methylation	3.445326e-5
GO:0043117	positive regulation of vascular permeability	3.704846e-5
GO:0016458	gene silencing	3.975007e-5
GO:0031145	anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process	4.005721e-5
GO:0030825	positive regulation of cGMP metabolic process	4.412600e-5
GO:0032516	positive regulation of phosphoprotein phosphatase activity	4.945101e-5
GO:0016070	RNA metabolic process	5.400184e-5
GO:0032515	negative regulation of phosphoprotein phosphatase activity	5.520345e-5
GO:0007006	mitochondrial membrane organization	6.330701e-5
GO:0010467	gene expression	6.696450e-5
GO:0043161	proteasomal ubiquitin-dependent protein catabolic process	6.738586e-5
GO:0032232	negative regulation of actin filament bundle assembly	7.066320e-5
GO:0031047	gene silencing by RNA	7.079089e-5
GO:0006590	thyroid hormone generation	7.124408e-5
GO:0060058	positive regulation of apoptosis involved in mammary gland involution	7.369096e-5
GO:0046602	regulation of mitotic centrosome separation	8.129775e-5
GO:0016142	O-glycoside catabolic process	8.270275e-5
GO:0010498	proteasomal protein catabolic process	8.712064e-5
GO:0035461	vitamin transmembrane transport	9.114033e-5
GO:0042136	neurotransmitter biosynthetic process	1.012304e-4
GO:0046666	retinal cell programmed cell death	1.165082e-4
GO:0031442	positive regulation of mRNA 3'-end processing	1.254991e-4
GO:0045956	positive regulation of calcium ion-dependent exocytosis	1.277426e-4
GO:0031536	positive regulation of exit from mitosis	1.351979e-4
GO:0042747	circadian sleep/wake cycle, REM sleep	1.417546e-4
GO:0032508	DNA duplex unwinding	1.439051e-4
GO:0070460	thyroid-stimulating hormone secretion	1.455330e-4
GO:0071359	cellular response to dsRNA	1.549603e-4
GO:0006396	RNA processing	1.629719e-4
GO:0071557	histone H3-K27 demethylation	1.660363e-4
GO:0035574	histone H4-K20 demethylation	1.660363e-4
GO:0060764	cell-cell signaling involved in mammary gland development	1.829462e-4
GO:0001777	T cell homeostatic proliferation	1.829462e-4
GO:0030828	positive regulation of cGMP biosynthetic process	1.912158e-4
GO:2000344	positive regulation of acrosome reaction	1.930504e-4
GO:0048008	platelet-derived growth factor receptor signaling pathway	1.940482e-4
GO:0002674	negative regulation of acute inflammatory response	1.998856e-4
GO:0032392	DNA geometric change	2.223597e-4
GO:0032479	regulation of type I interferon production	2.317018e-4
GO:0050428	3'-phosphoadenosine 5'-phosphosulfate biosynthetic process	2.333823e-4
GO:0071360	cellular response to exogenous dsRNA	2.386394e-4
GO:0042268	regulation of cytolysis	2.449228e-4
GO:0016926	protein desumoylation	2.449228e-4
GO:0009148	pyrimidine nucleoside triphosphate biosynthetic process	2.466667e-4
GO:0034332	adherens junction organization	2.548763e-4
GO:0019219	regulation of nucleobase-containing compound metabolic process	2.579136e-4
GO:0007049	cell cycle	2.740959e-4
GO:0030823	regulation of cGMP metabolic process	2.787692e-4
GO:0048597	post-embryonic camera-type eye morphogenesis	2.889321e-4
GO:0043414	macromolecule methylation	2.938006e-4
GO:0051171	regulation of nitrogen compound metabolic process	2.942729e-4
GO:0070059	apoptosis in response to endoplasmic reticulum stress	3.050753e-4
GO:0032481	positive regulation of type I interferon production	3.183486e-4
GO:0035303	regulation of dephosphorylation	3.271332e-4
GO:0015014	heparan sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process	3.276418e-4
GO:0016139	glycoside catabolic process	3.366317e-4
GO:0045713	low-density lipoprotein particle receptor biosynthetic process	3.366317e-4
GO:0045662	negative regulation of myoblast differentiation	3.404536e-4
GO:0010564	regulation of cell cycle process	3.504000e-4
GO:0006235	dTTP biosynthetic process	3.589307e-4
GO:0072197	ureter morphogenesis	3.593777e-4
GO:0070831	basement membrane assembly	3.695884e-4
GO:0006391	transcription initiation from mitochondrial promoter	3.695884e-4
GO:0018364	peptidyl-glutamine methylation	3.695884e-4
GO:0071872	cellular response to epinephrine stimulus	3.728997e-4
GO:0061014	positive regulation of mRNA catabolic process	4.109760e-4
GO:0031440	regulation of mRNA 3'-end processing	4.109760e-4
GO:0048227	plasma membrane to endosome transport	4.331307e-4
GO:0043123	positive regulation of I-kappaB kinase/NF-kappaB cascade	4.604672e-4
GO:0006044	N-acetylglucosamine metabolic process	4.609155e-4
GO:0070544	histone H3-K36 demethylation	4.613451e-4
GO:0006538	glutamate catabolic process	4.882722e-4
GO:0051974	negative regulation of telomerase activity	4.943151e-4
GO:0060013	righting reflex	5.393857e-4
GO:2000427	positive regulation of apoptotic cell clearance	5.420727e-4
GO:0080164	regulation of nitric oxide metabolic process	5.420727e-4
GO:0007057	spindle assembly involved in female meiosis I	5.420727e-4
GO:0000103	sulfate assimilation	5.653464e-4
GO:0035520	monoubiquitinated protein deubiquitination	5.821231e-4
GO:0010994	free ubiquitin chain polymerization	5.821231e-4
GO:0007525	somatic muscle development	6.295948e-4
GO:0033088	negative regulation of immature T cell proliferation in thymus	6.404259e-4
GO:0051414	response to cortisol stimulus	7.215935e-4
GO:2000016	negative regulation of determination of dorsal identity	7.476168e-4
GO:0000715	nucleotide-excision repair, DNA damage recognition	7.480333e-4
GO:0060336	negative regulation of interferon-gamma-mediated signaling pathway	7.480333e-4
GO:0022613	ribonucleoprotein complex biogenesis	7.619295e-4
GO:0044249	cellular biosynthetic process	7.765180e-4
GO:0006108	malate metabolic process	7.949107e-4
GO:0060433	bronchus development	8.727321e-4
GO:0032967	positive regulation of collagen biosynthetic process	8.774547e-4
GO:0044253	positive regulation of multicellular organismal metabolic process	9.213513e-4
GO:0032006	regulation of TOR signaling cascade	9.255668e-4
GO:0046125	pyrimidine deoxyribonucleoside metabolic process	9.412014e-4
GO:0051583	dopamine uptake	9.412014e-4
GO:0090304	nucleic acid metabolic process	9.510722e-4
GO:0010046	response to mycotoxin	9.566012e-4
GO:0006434	seryl-tRNA aminoacylation	9.566012e-4
GO:0034470	ncRNA processing	9.636750e-4
GO:0006139	nucleobase-containing compound metabolic process	1.008216e-3
GO:0051497	negative regulation of stress fiber assembly	1.055050e-3
GO:0006040	amino sugar metabolic process	1.126955e-3
GO:0003406	retinal pigment epithelium development	1.143262e-3
GO:0003221	right ventricular cardiac muscle tissue morphogenesis	1.143262e-3
GO:0010390	histone monoubiquitination	1.148003e-3
GO:0016072	rRNA metabolic process	1.155239e-3
GO:0006366	transcription from RNA polymerase II promoter	1.162296e-3
GO:0045921	positive regulation of exocytosis	1.174228e-3
GO:0072659	protein localization in plasma membrane	1.175171e-3
GO:0060480	lung goblet cell differentiation	1.188587e-3
GO:0060576	intestinal epithelial cell development	1.192112e-3
GO:0032331	negative regulation of chondrocyte differentiation	1.216675e-3
GO:0001502	cartilage condensation	1.227123e-3
GO:0006172	ADP biosynthetic process	1.250731e-3
GO:0016140	O-glycoside metabolic process	1.324029e-3
GO:0045358	negative regulation of interferon-beta biosynthetic process	1.324029e-3
GO:0009236	cobalamin biosynthetic process	1.324029e-3
GO:0002638	negative regulation of immunoglobulin production	1.324029e-3
GO:0001811	negative regulation of type I hypersensitivity	1.324029e-3
GO:0006863	purine base transport	1.325108e-3
GO:0007256	activation of JNKK activity	1.350491e-3
GO:0051301	cell division	1.438753e-3
GO:0072661	protein targeting to plasma membrane	1.504758e-3
GO:0032799	low-density lipoprotein receptor particle metabolic process	1.504758e-3
GO:0016577	histone demethylation	1.504761e-3
GO:0007096	regulation of exit from mitosis	1.516843e-3
GO:0045919	positive regulation of cytolysis	1.517006e-3
GO:0009597	detection of virus	1.517006e-3
GO:0010629	negative regulation of gene expression	1.640963e-3
GO:0007168	receptor guanylyl cyclase signaling pathway	1.658448e-3
GO:0072161	mesenchymal cell differentiation involved in kidney development	1.690773e-3
GO:0060005	vestibular reflex	1.690773e-3
GO:2000466	negative regulation of glycogen (starch) synthase activity	1.693521e-3
GO:0072040	negative regulation of mesenchymal stem cell apoptosis involved in nephron morphogenesis	1.739551e-3
GO:0002029	desensitization of G-protein coupled receptor protein signaling pathway	1.773606e-3
GO:0071168	protein localization to chromatin	1.778142e-3
GO:0007529	establishment of synaptic specificity at neuromuscular junction	1.785630e-3
GO:0051726	regulation of cell cycle	1.836545e-3
GO:0060047	heart contraction	1.840509e-3
GO:0051898	negative regulation of protein kinase B signaling cascade	1.858094e-3
GO:0051291	protein heterooligomerization	1.925122e-3
GO:0044246	regulation of multicellular organismal metabolic process	1.937784e-3
GO:0042996	regulation of Golgi to plasma membrane protein transport	1.945881e-3
GO:0050747	positive regulation of lipoprotein metabolic process	1.945881e-3
GO:0061360	optic chiasma development	1.945881e-3
GO:2000597	positive regulation of optic nerve formation	1.945881e-3
GO:0035799	ureter maturation	1.945881e-3
GO:0000415	negative regulation of histone H3-K36 methylation	1.945881e-3
GO:0018343	protein farnesylation	1.945881e-3
GO:0021633	optic nerve structural organization	1.945881e-3
GO:0021650	vestibulocochlear nerve formation	1.945881e-3
GO:0030264	nuclear fragmentation involved in apoptotic nuclear change	1.945881e-3
GO:0035786	protein complex oligomerization	1.945881e-3
GO:0000398	nuclear mRNA splicing, via spliceosome	2.007892e-3
GO:0050691	regulation of defense response to virus by host	2.040079e-3
GO:0060686	negative regulation of prostatic bud formation	2.079122e-3
GO:0032965	regulation of collagen biosynthetic process	2.091063e-3
GO:0000375	RNA splicing, via transesterification reactions	2.117252e-3
GO:0035414	negative regulation of catenin import into nucleus	2.119771e-3
GO:0006482	protein demethylation	2.196554e-3
GO:0033327	Leydig cell differentiation	2.330079e-3
GO:0000320	re-entry into mitotic cell cycle	2.330214e-3
GO:0072221	metanephric distal convoluted tubule development	2.336520e-3
GO:0006657	CDP-choline pathway	2.336520e-3
GO:0048147	negative regulation of fibroblast proliferation	2.400775e-3
GO:0045744	negative regulation of G-protein coupled receptor protein signaling pathway	2.400775e-3
GO:0090234	regulation of kinetochore assembly	2.439634e-3
GO:0090169	regulation of spindle assembly	2.439634e-3
GO:0060012	synaptic transmission, glycinergic	2.443210e-3
GO:0042789	mRNA transcription from RNA polymerase II promoter	2.443210e-3
GO:0042938	dipeptide transport	2.443210e-3
GO:0032239	regulation of nucleobase-containing compound transport	2.473412e-3
GO:0060992	response to fungicide	2.508577e-3
GO:0009058	biosynthetic process	2.527000e-3
GO:0008054	cyclin catabolic process	2.539889e-3
GO:0006390	transcription from mitochondrial promoter	2.565348e-3
GO:0002062	chondrocyte differentiation	2.615073e-3
GO:0044260	cellular macromolecule metabolic process	2.662334e-3
GO:0033599	regulation of mammary gland epithelial cell proliferation	2.751991e-3
GO:0072202	cell differentiation involved in metanephros development	2.779292e-3
GO:0060412	ventricular septum morphogenesis	2.784337e-3
GO:0042254	ribosome biogenesis	2.808217e-3
GO:0006997	nucleus organization	2.846387e-3
GO:0051972	regulation of telomerase activity	2.868566e-3
GO:0016068	type I hypersensitivity	2.906696e-3
GO:0071934	thiamine transmembrane transport	2.906696e-3
GO:0010070	zygote asymmetric cell division	2.906696e-3
GO:0010966	regulation of phosphate transport	2.906696e-3
GO:0002430	complement receptor mediated signaling pathway	2.906696e-3
GO:0006261	DNA-dependent DNA replication	2.977805e-3
GO:0051382	kinetochore assembly	3.036887e-3
GO:0050928	negative regulation of positive chemotaxis	3.085649e-3
GO:0042231	interleukin-13 biosynthetic process	3.085649e-3
GO:2000256	positive regulation of male germ cell proliferation	3.085649e-3
GO:0006285	base-excision repair, AP site formation	3.085649e-3
GO:0002462	tolerance induction to nonself antigen	3.085649e-3
GO:0010725	regulation of primitive erythrocyte differentiation	3.085649e-3
GO:0019428	allantoin biosynthetic process	3.085649e-3
GO:0000186	activation of MAPKK activity	3.180391e-3
GO:0015747	urate transport	3.227063e-3
GO:0042308	negative regulation of protein import into nucleus	3.307631e-3
GO:0051318	G1 phase	3.317748e-3
GO:0051383	kinetochore organization	3.338877e-3
GO:0006851	mitochondrial calcium ion transport	3.338877e-3
GO:0006418	tRNA aminoacylation for protein translation	3.356779e-3
GO:2000378	negative regulation of reactive oxygen species metabolic process	3.391166e-3
GO:0050849	negative regulation of calcium-mediated signaling	3.427601e-3
GO:0046847	filopodium assembly	3.498887e-3
GO:0001778	plasma membrane repair	3.525850e-3
GO:0035364	thymine transport	3.552829e-3
GO:0043000	Golgi to plasma membrane CFTR protein transport	3.552829e-3
GO:0035344	hypoxanthine transport	3.552829e-3
GO:0015853	adenine transport	3.552829e-3
GO:0006348	chromatin silencing at telomere	3.552829e-3
GO:0015854	guanine transport	3.552829e-3
GO:2000112	regulation of cellular macromolecule biosynthetic process	3.566756e-3
GO:0021978	telencephalon regionalization	3.614668e-3
GO:0060213	positive regulation of nuclear-transcribed mRNA poly(A) tail shortening	3.719948e-3
GO:0010159	specification of organ position	3.719948e-3
GO:0009147	pyrimidine nucleoside triphosphate metabolic process	3.720579e-3
GO:0071843	cellular component biogenesis at cellular level	3.721335e-3
GO:0033137	negative regulation of peptidyl-serine phosphorylation	3.817184e-3
GO:0051252	regulation of RNA metabolic process	3.897438e-3
GO:0030421	defecation	3.980830e-3
GO:0009817	defense response to fungus, incompatible interaction	3.980830e-3
GO:0006526	arginine biosynthetic process	3.980830e-3
GO:0016574	histone ubiquitination	4.070186e-3
GO:0008209	androgen metabolic process	4.142804e-3
GO:0070979	protein K11-linked ubiquitination	4.158012e-3
GO:0031947	negative regulation of glucocorticoid biosynthetic process	4.237766e-3
GO:0043968	histone H2A acetylation	4.314183e-3
GO:0032423	regulation of mismatch repair	4.475058e-3
GO:0048050	post-embryonic eye morphogenesis	4.522761e-3
GO:0060457	negative regulation of digestive system process	4.549822e-3
GO:0002575	basophil chemotaxis	4.549822e-3
GO:0060439	trachea morphogenesis	4.590759e-3
GO:0034641	cellular nitrogen compound metabolic process	4.601883e-3
GO:0071549	cellular response to dexamethasone stimulus	4.610773e-3
GO:0035518	histone H2A monoubiquitination	4.680542e-3
GO:0072240	metanephric DCT cell differentiation	4.708113e-3
GO:0019276	UDP-N-acetylgalactosamine metabolic process	4.708113e-3
GO:0072227	metanephric macula densa development	4.708113e-3
GO:0009065	glutamine family amino acid catabolic process	4.762400e-3
GO:0015851	nucleobase transport	4.819635e-3
GO:0042428	serotonin metabolic process	4.834638e-3
GO:2000736	regulation of stem cell differentiation	4.916467e-3
GO:0043457	regulation of cellular respiration	5.003185e-3
GO:0031573	intra-S DNA damage checkpoint	5.041391e-3
GO:0050689	negative regulation of defense response to virus by host	5.065776e-3
GO:0046607	positive regulation of centrosome cycle	5.065776e-3
GO:0046902	regulation of mitochondrial membrane permeability	5.224135e-3
GO:0010605	negative regulation of macromolecule metabolic process	5.279005e-3
GO:0000959	mitochondrial RNA metabolic process	5.473593e-3
GO:0060435	bronchiole development	5.486873e-3
GO:0050427	3'-phosphoadenosine 5'-phosphosulfate metabolic process	5.490807e-3
GO:0006807	nitrogen compound metabolic process	5.727439e-3
GO:0072179	nephric duct formation	5.739085e-3
GO:0003413	chondrocyte differentiation involved in endochondral bone morphogenesis	5.824705e-3
GO:0007264	small GTPase mediated signal transduction	5.836592e-3
GO:0006919	activation of caspase activity	5.860901e-3
GO:0090189	regulation of branching involved in ureteric bud morphogenesis	5.922754e-3
GO:0050685	positive regulation of mRNA processing	5.965532e-3
GO:0046108	uridine metabolic process	6.071369e-3
GO:0035611	protein branching point deglutamylation	6.071369e-3
GO:0021897	forebrain astrocyte development	6.071369e-3
GO:0042351	'de novo' GDP-L-fucose biosynthetic process	6.152574e-3
GO:0010312	detoxification of zinc ion	6.152574e-3
GO:0070934	CRD-mediated mRNA stabilization	6.203325e-3
GO:0017157	regulation of exocytosis	6.233204e-3
GO:0046293	formaldehyde biosynthetic process	6.272396e-3
GO:0048773	erythrophore differentiation	6.272396e-3
GO:0045872	positive regulation of rhodopsin gene expression	6.272396e-3
GO:0034021	response to silicon dioxide	6.272396e-3
GO:0001315	age-dependent response to reactive oxygen species	6.272396e-3
GO:0003069	vasodilation by acetylcholine involved in regulation of systemic arterial blood pressure	6.272396e-3
GO:0043252	sodium-independent organic anion transport	6.272396e-3
GO:0051280	negative regulation of release of sequestered calcium ion into cytosol	6.319221e-3
GO:0033578	protein glycosylation in Golgi	6.335875e-3
GO:0002865	negative regulation of acute inflammatory response to antigenic stimulus	6.335875e-3
GO:0001757	somite specification	6.335875e-3
GO:0006355	regulation of transcription, DNA-dependent	6.339063e-3
GO:0006364	rRNA processing	6.459675e-3
GO:0006351	transcription, DNA-dependent	6.494960e-3
GO:0006105	succinate metabolic process	6.523360e-3
GO:2000064	regulation of cortisol biosynthetic process	6.579866e-3
GO:0072076	nephrogenic mesenchyme development	6.579866e-3
GO:0046831	regulation of RNA export from nucleus	6.579866e-3
GO:0070171	negative regulation of tooth mineralization	6.579866e-3
GO:0043932	ossification involved in bone remodeling	6.584439e-3
GO:0009235	cobalamin metabolic process	6.584439e-3
GO:0007262	STAT protein import into nucleus	6.623981e-3
GO:0006983	ER overload response	6.903581e-3
GO:0003015	heart process	6.923312e-3
GO:0009451	RNA modification	6.984291e-3
GO:0010452	histone H3-K36 methylation	6.993411e-3
GO:0035993	deltoid tuberosity development	7.011210e-3
GO:0016075	rRNA catabolic process	7.011210e-3
GO:0006213	pyrimidine nucleoside metabolic process	7.190204e-3
GO:0051589	negative regulation of neurotransmitter transport	7.257953e-3
GO:0060390	regulation of SMAD protein import into nucleus	7.317628e-3
GO:0072074	kidney mesenchyme development	7.325284e-3
GO:0032774	RNA biosynthetic process	7.384305e-3
GO:0003073	regulation of systemic arterial blood pressure	7.514172e-3
GO:0034645	cellular macromolecule biosynthetic process	7.529226e-3
GO:0090103	cochlea morphogenesis	7.531047e-3
GO:0032008	positive regulation of TOR signaling cascade	7.536495e-3
GO:0006354	transcription elongation, DNA-dependent	7.576607e-3
GO:0046514	ceramide catabolic process	7.660613e-3
GO:0032648	regulation of interferon-beta production	7.690616e-3
GO:2000623	negative regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay	7.709037e-3
GO:0045684	positive regulation of epidermis development	7.734974e-3
GO:2000036	regulation of stem cell maintenance	7.734974e-3
GO:0045646	regulation of erythrocyte differentiation	7.764939e-3
GO:0031326	regulation of cellular biosynthetic process	7.985120e-3
GO:2000242	negative regulation of reproductive process	8.014064e-3
GO:0030433	ER-associated protein catabolic process	8.139040e-3
GO:0060739	mesenchymal-epithelial cell signaling involved in prostate gland development	8.202384e-3
GO:0072134	nephrogenic mesenchyme morphogenesis	8.202384e-3
GO:0051660	establishment of centrosome localization	8.202384e-3
GO:0021540	corpus callosum morphogenesis	8.202384e-3
GO:0009409	response to cold	8.254647e-3
GO:0043330	response to exogenous dsRNA	8.263678e-3
GO:0048593	camera-type eye morphogenesis	8.311894e-3
GO:0010922	positive regulation of phosphatase activity	8.477193e-3
GO:0071901	negative regulation of protein serine/threonine kinase activity	8.497949e-3
GO:0010556	regulation of macromolecule biosynthetic process	8.563088e-3
GO:0010952	positive regulation of peptidase activity	8.721250e-3
GO:0061037	negative regulation of cartilage development	8.857671e-3
GO:0010524	positive regulation of calcium ion transport into cytosol	8.905491e-3
GO:0002358	B cell homeostatic proliferation	8.915891e-3
GO:0001986	negative regulation of the force of heart contraction involved in baroreceptor response to increased systemic arterial blood pressure	8.915891e-3
GO:0007144	female meiosis I	9.097259e-3
GO:0002248	connective tissue replacement involved in inflammatory response wound healing	9.168540e-3
GO:0030970	retrograde protein transport, ER to cytosol	9.226561e-3
GO:0021758	putamen development	9.226561e-3
GO:0021757	caudate nucleus development	9.226561e-3
GO:0009059	macromolecule biosynthetic process	9.245192e-3
GO:0030035	microspike assembly	9.326299e-3
GO:0019933	cAMP-mediated signaling	9.584322e-3
GO:0061046	regulation of branching involved in lung morphogenesis	9.591054e-3
GO:0032387	negative regulation of intracellular transport	9.648518e-3
GO:0033135	regulation of peptidyl-serine phosphorylation	9.774037e-3
GO:0032025	response to cobalt ion	9.895583e-3
GO:0090190	positive regulation of branching involved in ureteric bud morphogenesis	1.005628e-2
GO:0051457	maintenance of protein location in nucleus	1.016583e-2
GO:0071479	cellular response to ionizing radiation	1.019040e-2
GO:0072527	pyrimidine-containing compound metabolic process	1.036722e-2
GO:0043280	positive regulation of caspase activity	1.036803e-2
GO:0009452	RNA capping	1.048225e-2
GO:0006941	striated muscle contraction	1.050209e-2
GO:0001504	neurotransmitter uptake	1.050929e-2
GO:0006702	androgen biosynthetic process	1.056301e-2
GO:2000065	negative regulation of cortisol biosynthetic process	1.062573e-2
GO:0009088	threonine biosynthetic process	1.062573e-2
GO:0051610	serotonin uptake	1.062573e-2
GO:0032348	negative regulation of aldosterone biosynthetic process	1.062573e-2
GO:0045023	G0 to G1 transition	1.062573e-2
GO:0010107	potassium ion import	1.086676e-2
GO:0010950	positive regulation of endopeptidase activity	1.104219e-2
GO:0045428	regulation of nitric oxide biosynthetic process	1.133554e-2
GO:0001841	neural tube formation	1.162885e-2
GO:0003166	bundle of His development	1.166556e-2
GO:0007097	nuclear migration	1.179131e-2
GO:0033683	nucleotide-excision repair, DNA incision	1.182146e-2
GO:0016081	synaptic vesicle docking involved in exocytosis	1.182146e-2
GO:0033522	histone H2A ubiquitination	1.185033e-2
GO:0032353	negative regulation of hormone biosynthetic process	1.186655e-2
GO:0006646	phosphatidylethanolamine biosynthetic process	1.186655e-2
GO:0010803	regulation of tumor necrosis factor-mediated signaling pathway	1.196589e-2
GO:0045429	positive regulation of nitric oxide biosynthetic process	1.196830e-2
GO:0003281	ventricular septum development	1.216944e-2
GO:0060685	regulation of prostatic bud formation	1.251225e-2
GO:0046103	inosine biosynthetic process	1.252176e-2
GO:0006154	adenosine catabolic process	1.252176e-2
GO:2000009	negative regulation of protein localization at cell surface	1.258510e-2
GO:0007207	activation of phospholipase C activity by muscarinic acetylcholine receptor signaling pathway	1.258510e-2
GO:0045083	negative regulation of interleukin-12 biosynthetic process	1.259095e-2
GO:0009299	mRNA transcription	1.259095e-2
GO:0090224	regulation of spindle organization	1.265860e-2
GO:0034651	cortisol biosynthetic process	1.287022e-2
GO:0019064	viral envelope fusion with host membrane	1.287022e-2
GO:0035865	cellular response to potassium ion	1.287022e-2
GO:0046814	virion attachment, binding of host cell surface coreceptor	1.287022e-2
GO:0015887	pantothenate transmembrane transport	1.287022e-2
GO:0006666	3-keto-sphinganine metabolic process	1.287022e-2
GO:0015878	biotin transport	1.287022e-2
GO:0018206	peptidyl-methionine modification	1.295386e-2
GO:0006565	L-serine catabolic process	1.295386e-2
GO:0007569	cell aging	1.300679e-2
GO:0071285	cellular response to lithium ion	1.302608e-2
GO:0002063	chondrocyte development	1.345268e-2
GO:0051798	positive regulation of hair follicle development	1.366307e-2
GO:0006744	ubiquinone biosynthetic process	1.368107e-2
GO:0046823	negative regulation of nucleocytoplasmic transport	1.368866e-2
GO:0033523	histone H2B ubiquitination	1.375072e-2
GO:0006241	CTP biosynthetic process	1.376240e-2
GO:0071257	cellular response to electrical stimulus	1.376240e-2
GO:0009435	NAD biosynthetic process	1.376240e-2
GO:0042276	error-prone translesion synthesis	1.389095e-2
GO:0032011	ARF protein signal transduction	1.389095e-2
GO:0038007	netrin-activated signaling pathway	1.389095e-2
GO:0019935	cyclic-nucleotide-mediated signaling	1.413294e-2
GO:0000075	cell cycle checkpoint	1.413294e-2
GO:0008210	estrogen metabolic process	1.437513e-2
GO:0007076	mitotic chromosome condensation	1.447044e-2
GO:0072162	metanephric mesenchymal cell differentiation	1.452840e-2
GO:0071711	basement membrane organization	1.452840e-2
GO:0031077	post-embryonic camera-type eye development	1.470195e-2
GO:0000183	chromatin silencing at rDNA	1.482141e-2
GO:0040001	establishment of mitotic spindle localization	1.490329e-2
GO:0045292	nuclear mRNA cis splicing, via spliceosome	1.516898e-2
GO:0010447	response to acidity	1.516898e-2
GO:0018022	peptidyl-lysine methylation	1.536843e-2
GO:0046677	response to antibiotic	1.547332e-2
GO:0045661	regulation of myoblast differentiation	1.548944e-2
GO:0006220	pyrimidine nucleotide metabolic process	1.550380e-2
GO:2000377	regulation of reactive oxygen species metabolic process	1.556233e-2
GO:0034767	positive regulation of ion transmembrane transport	1.559605e-2
GO:0007260	tyrosine phosphorylation of STAT protein	1.559605e-2
GO:0035117	embryonic arm morphogenesis	1.584079e-2
GO:0006379	mRNA cleavage	1.595592e-2
GO:0071407	cellular response to organic cyclic compound	1.608724e-2
GO:0031323	regulation of cellular metabolic process	1.646615e-2
GO:0090002	establishment of protein localization in plasma membrane	1.665561e-2
GO:0002230	positive regulation of defense response to virus by host	1.665561e-2
GO:0006419	alanyl-tRNA aminoacylation	1.677261e-2
GO:0046184	aldehyde biosynthetic process	1.677261e-2
GO:0061084	negative regulation of protein refolding	1.677261e-2
GO:0003130	BMP signaling pathway involved in heart induction	1.677261e-2
GO:0000414	regulation of histone H3-K36 methylation	1.677261e-2
GO:0002069	columnar/cuboidal epithelial cell maturation	1.677261e-2
GO:0006122	mitochondrial electron transport, ubiquinol to cytochrome c	1.677261e-2
GO:0051148	negative regulation of muscle cell differentiation	1.682778e-2
GO:0070727	cellular macromolecule localization	1.684452e-2
GO:0007188	G-protein signaling, coupled to cAMP nucleotide second messenger	1.689593e-2
GO:0050872	white fat cell differentiation	1.691501e-2
GO:0043331	response to dsRNA	1.705575e-2
GO:0071894	histone H2B conserved C-terminal lysine ubiquitination	1.705826e-2
GO:0071585	detoxification of cadmium ion	1.705826e-2
GO:0000053	argininosuccinate metabolic process	1.705826e-2
GO:0034048	negative regulation of protein phosphatase type 2A activity	1.705826e-2
GO:0045836	positive regulation of meiosis	1.717121e-2
GO:0030866	cortical actin cytoskeleton organization	1.745322e-2
GO:0060931	sinoatrial node cell development	1.748970e-2
GO:0003167	atrioventricular bundle cell differentiation	1.748970e-2
GO:0072233	metanephric thick ascending limb development	1.750223e-2
GO:0072218	metanephric ascending thin limb development	1.750223e-2
GO:0060014	granulosa cell differentiation	1.750223e-2
GO:0009202	deoxyribonucleoside triphosphate biosynthetic process	1.750223e-2
GO:0018026	peptidyl-lysine monomethylation	1.755289e-2
GO:0002066	columnar/cuboidal epithelial cell development	1.755289e-2
GO:0008015	blood circulation	1.762187e-2
GO:0034613	cellular protein localization	1.762784e-2
GO:0071897	DNA biosynthetic process	1.774969e-2
GO:0090009	primitive streak formation	1.782412e-2
GO:0072537	fibroblast activation	1.785622e-2
GO:0032608	interferon-beta production	1.785622e-2
GO:0031109	microtubule polymerization or depolymerization	1.789570e-2
GO:0070936	protein K48-linked ubiquitination	1.794458e-2