Novel motif:128

name:	motif128_NNGNATRCGWN

Association to promoter expression in human samples<b>Summary:</b>Significance of the correlation with CAGE expression, human <br><b>Analyst:</b> Michiel de Hoon<br><br>link to source dataset <br>data

---

Association to promoter expression in mouse samples <b>Summary:</b>Significance of the correlation with CAGE expression, mouse <br><b>Analyst:</b> Michiel de Hoon<br><br>link to source dataset <br>data

---

GREAT analysis results for human <b>Summary:</b>Genomic Enrichment of Annotations Tool (GREAT, Nat Biotechnol. 2010 May;28(5):495-501) is used to identify, both in human and in mouse, the gene ontology terms of biological processes enriched given the predicted TFBSs, and evaluated the overlap in the top-500 gene ontology terms between human and mouse. For each novel motif, the P value for the overlap was then evaluated by calculating its relative rank with respect to this background distribution.<br>Analyst: Michiel de Hoon<br><br>link to source dataset <br>data

---

GO ID	GO Term	p-value
GO:0038028	insulin receptor signaling pathway via phosphatidylinositol 3-kinase cascade	6.987092e-17
GO:0046628	positive regulation of insulin receptor signaling pathway	2.353353e-16
GO:2000467	positive regulation of glycogen (starch) synthase activity	7.838348e-14
GO:2000465	regulation of glycogen (starch) synthase activity	6.404163e-12
GO:0090031	positive regulation of steroid hormone biosynthetic process	1.152636e-11
GO:0006349	regulation of gene expression by genetic imprinting	1.480494e-11
GO:0031442	positive regulation of mRNA 3'-end processing	2.701908e-11
GO:0031017	exocrine pancreas development	5.785423e-10
GO:0070875	positive regulation of glycogen metabolic process	2.657263e-9
GO:0035435	phosphate ion transmembrane transport	3.852461e-9
GO:0045725	positive regulation of glycogen biosynthetic process	4.474974e-9
GO:0050685	positive regulation of mRNA processing	8.903607e-9
GO:0046886	positive regulation of hormone biosynthetic process	1.087525e-8
GO:0071514	genetic imprinting	1.614609e-8
GO:0006412	translation	2.504566e-8
GO:0031440	regulation of mRNA 3'-end processing	2.750077e-8
GO:0030505	inorganic diphosphate transport	3.679949e-8
GO:0006281	DNA repair	7.692053e-8
GO:0007128	meiotic prophase I	1.639138e-7
GO:0006982	response to lipid hydroperoxide	1.714344e-7
GO:0006401	RNA catabolic process	1.979414e-7
GO:0051225	spindle assembly	2.045802e-7
GO:0042703	menstruation	2.365237e-7
GO:0019101	female somatic sex determination	2.365237e-7
GO:0061014	positive regulation of mRNA catabolic process	2.511264e-7
GO:0097045	phosphatidylserine exposure on blood platelet	3.071750e-7
GO:0051310	metaphase plate congression	3.169962e-7
GO:2000121	regulation of removal of superoxide radicals	3.262245e-7
GO:0006402	mRNA catabolic process	3.338375e-7
GO:0032515	negative regulation of phosphoprotein phosphatase activity	3.495358e-7
GO:0035308	negative regulation of protein dephosphorylation	3.495358e-7
GO:0090030	regulation of steroid hormone biosynthetic process	4.082076e-7
GO:0007051	spindle organization	5.903813e-7
GO:0006189	'de novo' IMP biosynthetic process	7.139952e-7
GO:0002074	extraocular skeletal muscle development	8.367437e-7
GO:2000273	positive regulation of receptor activity	9.483004e-7
GO:0000019	regulation of mitotic recombination	1.115153e-6
GO:0002238	response to molecule of fungal origin	1.129142e-6
GO:0003199	endocardial cushion to mesenchymal transition involved in heart valve formation	1.268423e-6
GO:0018872	arsonoacetate metabolic process	1.268423e-6
GO:0051324	prophase	1.428966e-6
GO:0060052	neurofilament cytoskeleton organization	1.649578e-6
GO:2000620	positive regulation of histone H4-K16 acetylation	1.828732e-6
GO:2000617	positive regulation of histone H3-K9 acetylation	1.828732e-6
GO:0070512	positive regulation of histone H4-K20 methylation	1.828732e-6
GO:0008334	histone mRNA metabolic process	1.848064e-6
GO:0007060	male meiosis chromosome segregation	2.616623e-6
GO:0051257	spindle midzone assembly involved in meiosis	2.616623e-6
GO:0032352	positive regulation of hormone metabolic process	2.626777e-6
GO:0060213	positive regulation of nuclear-transcribed mRNA poly(A) tail shortening	2.629405e-6
GO:0006471	protein ADP-ribosylation	2.728682e-6
GO:0035305	negative regulation of dephosphorylation	3.331509e-6
GO:0010893	positive regulation of steroid biosynthetic process	3.518936e-6
GO:0042998	positive regulation of Golgi to plasma membrane protein transport	3.759453e-6
GO:0006424	glutamyl-tRNA aminoacylation	3.863115e-6
GO:0006313	transposition, DNA-mediated	3.942833e-6
GO:0006302	double-strand break repair	3.989453e-6
GO:0002543	activation of blood coagulation via clotting cascade	4.115786e-6
GO:0043467	regulation of generation of precursor metabolites and energy	4.613712e-6
GO:0051131	chaperone-mediated protein complex assembly	4.845977e-6
GO:0060014	granulosa cell differentiation	8.155535e-6
GO:0061013	regulation of mRNA catabolic process	8.958206e-6
GO:0000289	nuclear-transcribed mRNA poly(A) tail shortening	9.355491e-6
GO:0006396	RNA processing	9.863316e-6
GO:0071169	establishment of protein localization to chromatin	1.093867e-5
GO:0048240	sperm capacitation	1.144361e-5
GO:0022613	ribonucleoprotein complex biogenesis	1.270139e-5
GO:0005978	glycogen biosynthetic process	1.429060e-5
GO:0048561	establishment of organ orientation	1.462822e-5
GO:0010923	negative regulation of phosphatase activity	1.463440e-5
GO:0046006	regulation of activated T cell proliferation	1.523235e-5
GO:0030237	female sex determination	1.548004e-5
GO:0090086	negative regulation of protein deubiquitination	1.629029e-5
GO:0046885	regulation of hormone biosynthetic process	1.669680e-5
GO:0032864	activation of Cdc42 GTPase activity	1.890595e-5
GO:0010907	positive regulation of glucose metabolic process	1.907227e-5
GO:0000079	regulation of cyclin-dependent protein kinase activity	1.915990e-5
GO:0042254	ribosome biogenesis	1.961463e-5
GO:0071044	histone mRNA catabolic process	1.987037e-5
GO:0007080	mitotic metaphase plate congression	2.038325e-5
GO:0034394	protein localization at cell surface	2.340117e-5
GO:0006368	transcription elongation from RNA polymerase II promoter	2.625995e-5
GO:0043060	meiotic metaphase I plate congression	2.980814e-5
GO:0051573	negative regulation of histone H3-K9 methylation	3.024734e-5
GO:0070873	regulation of glycogen metabolic process	3.254618e-5
GO:0031124	mRNA 3'-end processing	3.295949e-5
GO:0000956	nuclear-transcribed mRNA catabolic process	3.600043e-5
GO:0051004	regulation of lipoprotein lipase activity	3.746561e-5
GO:0000723	telomere maintenance	3.812429e-5
GO:0060236	regulation of mitotic spindle organization	3.915311e-5
GO:0042104	positive regulation of activated T cell proliferation	3.932869e-5
GO:0050779	RNA destabilization	3.953215e-5
GO:0018993	somatic sex determination	3.999639e-5
GO:0006354	transcription elongation, DNA-dependent	4.437040e-5
GO:0090084	negative regulation of inclusion body assembly	5.414712e-5
GO:0045162	clustering of voltage-gated sodium channels	5.602209e-5
GO:0016072	rRNA metabolic process	5.656076e-5
GO:0033194	response to hydroperoxide	6.216629e-5
GO:0072393	microtubule anchoring at microtubule organizing center	6.364294e-5
GO:0005979	regulation of glycogen biosynthetic process	6.368194e-5
GO:0060623	regulation of chromosome condensation	6.562439e-5
GO:0071283	cellular response to iron(III) ion	6.562439e-5
GO:0046680	response to DDT	6.562439e-5
GO:0043456	regulation of pentose-phosphate shunt	6.562439e-5
GO:0051987	positive regulation of attachment of spindle microtubules to kinetochore	6.562439e-5
GO:0071843	cellular component biogenesis at cellular level	7.856369e-5
GO:0060879	semicircular canal fusion	8.018032e-5
GO:0061115	lung proximal/distal axis specification	8.018032e-5
GO:0070352	positive regulation of white fat cell proliferation	8.018032e-5
GO:0060661	submandibular salivary gland formation	8.018032e-5
GO:0060496	mesenchymal-epithelial cell signaling involved in lung development	8.018032e-5
GO:0050677	positive regulation of urothelial cell proliferation	8.018032e-5
GO:0050674	urothelial cell proliferation	8.018032e-5
GO:0060436	bronchiole morphogenesis	8.018032e-5
GO:0021586	pons maturation	8.117209e-5
GO:0006391	transcription initiation from mitochondrial promoter	8.177414e-5
GO:0030433	ER-associated protein catabolic process	8.475418e-5
GO:0031572	G2/M transition DNA damage checkpoint	1.007479e-4
GO:0014878	response to electrical stimulus involved in regulation of muscle adaptation	1.012818e-4
GO:0042776	mitochondrial ATP synthesis coupled proton transport	1.013761e-4
GO:0006310	DNA recombination	1.027537e-4
GO:0000726	non-recombinational repair	1.031472e-4
GO:0031123	RNA 3'-end processing	1.069205e-4
GO:0006680	glucosylceramide catabolic process	1.090018e-4
GO:0044205	'de novo' UMP biosynthetic process	1.090018e-4
GO:0006188	IMP biosynthetic process	1.136464e-4
GO:0006303	double-strand break repair via nonhomologous end joining	1.217038e-4
GO:0006364	rRNA processing	1.262762e-4
GO:0006363	termination of RNA polymerase I transcription	1.281658e-4
GO:0071477	cellular hypotonic salinity response	1.431587e-4
GO:0034633	retinol transport	1.431587e-4
GO:0000239	pachytene	1.460769e-4
GO:0035020	regulation of Rac protein signal transduction	1.468015e-4
GO:0006713	glucocorticoid catabolic process	1.474338e-4
GO:2000660	negative regulation of interleukin-1-mediated signaling pathway	1.545071e-4
GO:0045940	positive regulation of steroid metabolic process	1.562296e-4
GO:0006353	transcription termination, DNA-dependent	1.572772e-4
GO:0045950	negative regulation of mitotic recombination	1.660956e-4
GO:0019532	oxalate transport	1.761862e-4
GO:0008210	estrogen metabolic process	1.800500e-4
GO:0070925	organelle assembly	1.879272e-4
GO:0090322	regulation of superoxide metabolic process	1.955782e-4
GO:0030953	astral microtubule organization	2.004081e-4
GO:0045176	apical protein localization	2.013085e-4
GO:0034241	positive regulation of macrophage fusion	2.064787e-4
GO:0034197	triglyceride transport	2.064787e-4
GO:0000073	spindle pole body separation	2.064787e-4
GO:0032200	telomere organization	2.107733e-4
GO:0006817	phosphate ion transport	2.163643e-4
GO:0019318	hexose metabolic process	2.167004e-4
GO:0008355	olfactory learning	2.252686e-4
GO:0008286	insulin receptor signaling pathway	2.304269e-4
GO:0085020	protein K6-linked ubiquitination	2.569165e-4
GO:0072385	minus-end-directed organelle transport along microtubule	2.757624e-4
GO:0046599	regulation of centriole replication	2.780380e-4
GO:0042987	amyloid precursor protein catabolic process	2.952059e-4
GO:0032790	ribosome disassembly	3.003608e-4
GO:0032212	positive regulation of telomere maintenance via telomerase	3.081171e-4
GO:0070075	tear secretion	3.088362e-4
GO:0043004	cytoplasmic sequestering of CFTR protein	3.088362e-4
GO:0044265	cellular macromolecule catabolic process	3.104888e-4
GO:0000288	nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay	3.122435e-4
GO:0031167	rRNA methylation	3.321215e-4
GO:0050916	sensory perception of sweet taste	3.347773e-4
GO:0051255	spindle midzone assembly	3.716592e-4
GO:0006482	protein demethylation	3.729420e-4
GO:0090085	regulation of protein deubiquitination	3.731557e-4
GO:0010676	positive regulation of cellular carbohydrate metabolic process	3.763390e-4
GO:0070346	positive regulation of fat cell proliferation	4.001389e-4
GO:0060339	negative regulation of type I interferon-mediated signaling pathway	4.001389e-4
GO:0035494	SNARE complex disassembly	4.001389e-4
GO:0009057	macromolecule catabolic process	4.135201e-4
GO:0050668	positive regulation of homocysteine metabolic process	4.454596e-4
GO:0045963	negative regulation of dopamine metabolic process	4.454596e-4
GO:0043148	mitotic spindle stabilization	4.454596e-4
GO:0060435	bronchiole development	4.474890e-4
GO:0050917	sensory perception of umami taste	4.631537e-4
GO:0042996	regulation of Golgi to plasma membrane protein transport	4.631537e-4
GO:0055024	regulation of cardiac muscle tissue development	4.701612e-4
GO:0031576	G2/M transition checkpoint	4.716475e-4
GO:0016095	polyprenol catabolic process	4.921444e-4
GO:0006433	prolyl-tRNA aminoacylation	4.921444e-4
GO:0048752	semicircular canal morphogenesis	4.939365e-4
GO:0035094	response to nicotine	5.004125e-4
GO:0035304	regulation of protein dephosphorylation	5.074913e-4
GO:0000724	double-strand break repair via homologous recombination	5.149129e-4
GO:0042048	olfactory behavior	5.200625e-4
GO:0021993	initiation of neural tube closure	5.200625e-4
GO:0034048	negative regulation of protein phosphatase type 2A activity	5.200625e-4
GO:0007140	male meiosis	5.279204e-4
GO:0035022	positive regulation of Rac protein signal transduction	5.333925e-4
GO:0006405	RNA export from nucleus	5.827088e-4
GO:0021666	rhombomere 5 formation	6.230833e-4
GO:0021660	rhombomere 3 formation	6.230833e-4
GO:0000725	recombinational repair	6.289739e-4
GO:0060461	right lung morphogenesis	6.321563e-4
GO:0060446	branching involved in open tracheal system development	6.321563e-4
GO:0090131	mesenchyme migration	6.321563e-4
GO:0014822	detection of wounding	6.321563e-4
GO:0043633	polyadenylation-dependent RNA catabolic process	6.321563e-4
GO:0048371	lateral mesodermal cell differentiation	6.321563e-4
GO:0048613	embryonic ectodermal digestive tract morphogenesis	6.321563e-4
GO:0090224	regulation of spindle organization	6.429356e-4
GO:2000615	regulation of histone H3-K9 acetylation	6.661586e-4
GO:0006361	transcription initiation from RNA polymerase I promoter	7.019692e-4
GO:0048807	female genitalia morphogenesis	7.145270e-4
GO:0050434	positive regulation of viral transcription	7.703185e-4
GO:0000226	microtubule cytoskeleton organization	8.211403e-4
GO:0008612	peptidyl-lysine modification to hypusine	8.216714e-4
GO:0008057	eye pigment granule organization	8.421028e-4
GO:0006348	chromatin silencing at telomere	8.488796e-4
GO:0060043	regulation of cardiac muscle cell proliferation	8.582628e-4
GO:0032508	DNA duplex unwinding	8.758858e-4
GO:0006308	DNA catabolic process	8.762909e-4
GO:0034063	stress granule assembly	9.168165e-4
GO:0046782	regulation of viral transcription	9.252305e-4
GO:0000154	rRNA modification	9.391090e-4
GO:0051321	meiotic cell cycle	1.018499e-3
GO:0055021	regulation of cardiac muscle tissue growth	1.022979e-3
GO:0030262	apoptotic nuclear change	1.057043e-3
GO:0008298	intracellular mRNA localization	1.122650e-3
GO:0070544	histone H3-K36 demethylation	1.129507e-3
GO:0050666	regulation of homocysteine metabolic process	1.130393e-3
GO:0032350	regulation of hormone metabolic process	1.164087e-3
GO:0046889	positive regulation of lipid biosynthetic process	1.166831e-3
GO:0045143	homologous chromosome segregation	1.184447e-3
GO:0046513	ceramide biosynthetic process	1.193187e-3
GO:0006051	N-acetylmannosamine metabolic process	1.195475e-3
GO:0046600	negative regulation of centriole replication	1.207046e-3
GO:0008105	asymmetric protein localization	1.250875e-3
GO:0070350	regulation of white fat cell proliferation	1.299298e-3
GO:0032392	DNA geometric change	1.381783e-3
GO:0046512	sphingosine biosynthetic process	1.387559e-3
GO:0005996	monosaccharide metabolic process	1.392740e-3
GO:0001539	ciliary or flagellar motility	1.420855e-3
GO:0051006	positive regulation of lipoprotein lipase activity	1.474801e-3
GO:0060340	positive regulation of type I interferon-mediated signaling pathway	1.575411e-3
GO:0009946	proximal/distal axis specification	1.588910e-3
GO:0010833	telomere maintenance via telomere lengthening	1.605765e-3
GO:0031638	zymogen activation	1.633251e-3
GO:0030540	female genitalia development	1.633457e-3
GO:0051984	positive regulation of chromosome segregation	1.727137e-3
GO:0046587	positive regulation of calcium-dependent cell-cell adhesion	1.727137e-3
GO:0032206	positive regulation of telomere maintenance	1.731090e-3
GO:0048680	positive regulation of axon regeneration	1.772112e-3
GO:0034470	ncRNA processing	1.809321e-3
GO:0060026	convergent extension	1.845734e-3
GO:0090083	regulation of inclusion body assembly	1.880663e-3
GO:0035883	enteroendocrine cell differentiation	1.892209e-3
GO:0060338	regulation of type I interferon-mediated signaling pathway	1.907966e-3
GO:2001022	positive regulation of response to DNA damage stimulus	1.914816e-3
GO:0006983	ER overload response	1.922893e-3
GO:0060356	leucine import	1.925053e-3
GO:0048242	epinephrine secretion	1.925053e-3
GO:0060977	coronary vasculature morphogenesis	1.993992e-3
GO:0031639	plasminogen activation	2.066457e-3
GO:0030148	sphingolipid biosynthetic process	2.200320e-3
GO:0034115	negative regulation of heterotypic cell-cell adhesion	2.230163e-3
GO:0051534	negative regulation of NFAT protein import into nucleus	2.237466e-3
GO:0010216	maintenance of DNA methylation	2.257264e-3
GO:0051081	nuclear envelope disassembly	2.291281e-3
GO:0045198	establishment of epithelial cell apical/basal polarity	2.352079e-3
GO:0046520	sphingoid biosynthetic process	2.359681e-3
GO:0070384	Harderian gland development	2.388856e-3
GO:0006741	NADP biosynthetic process	2.402985e-3
GO:0051791	medium-chain fatty acid metabolic process	2.402985e-3
GO:0015074	DNA integration	2.423670e-3
GO:0045840	positive regulation of mitosis	2.491303e-3
GO:0070212	protein poly-ADP-ribosylation	2.503988e-3
GO:0006403	RNA localization	2.547383e-3
GO:0048808	male genitalia morphogenesis	2.641141e-3
GO:0071476	cellular hypotonic response	2.653199e-3
GO:0051571	positive regulation of histone H3-K4 methylation	2.677004e-3
GO:0060179	male mating behavior	2.755347e-3
GO:0006611	protein export from nucleus	2.794105e-3
GO:0010807	regulation of synaptic vesicle priming	2.795055e-3
GO:0006282	regulation of DNA repair	2.866770e-3
GO:0007286	spermatid development	2.949041e-3
GO:0071557	histone H3-K27 demethylation	3.015464e-3
GO:0035574	histone H4-K20 demethylation	3.015464e-3
GO:0006678	glucosylceramide metabolic process	3.039022e-3
GO:0071472	cellular response to salt stress	3.057408e-3
GO:0042946	glucoside transport	3.076261e-3
GO:0035852	horizontal cell localization	3.076261e-3
GO:0051793	medium-chain fatty acid catabolic process	3.076261e-3
GO:2000768	positive regulation of nephron tubule epithelial cell differentiation	3.076261e-3
GO:0035502	metanephric ureteric bud development	3.076261e-3
GO:0035846	oviduct epithelium development	3.076261e-3
GO:0035847	uterine epithelium development	3.076261e-3
GO:0035849	nephric duct elongation	3.076261e-3
GO:0006006	glucose metabolic process	3.207561e-3
GO:0002642	positive regulation of immunoglobulin biosynthetic process	3.240644e-3
GO:0033169	histone H3-K9 demethylation	3.251903e-3
GO:0001649	osteoblast differentiation	3.275533e-3
GO:0045739	positive regulation of DNA repair	3.344211e-3
GO:0060045	positive regulation of cardiac muscle cell proliferation	3.345127e-3
GO:0006892	post-Golgi vesicle-mediated transport	3.417021e-3
GO:0002331	pre-B cell allelic exclusion	3.507013e-3
GO:0006309	DNA fragmentation involved in apoptotic nuclear change	3.713576e-3
GO:0042026	protein refolding	3.733048e-3
GO:0032210	regulation of telomere maintenance via telomerase	3.764336e-3
GO:0034502	protein localization to chromosome	3.783752e-3
GO:0009083	branched chain family amino acid catabolic process	3.812510e-3
GO:0071168	protein localization to chromatin	3.815904e-3
GO:0048370	lateral mesoderm formation	3.815904e-3
GO:0048560	establishment of anatomical structure orientation	3.815904e-3
GO:0050684	regulation of mRNA processing	3.841556e-3
GO:0021678	third ventricle development	4.005183e-3
GO:0090399	replicative senescence	4.049346e-3
GO:0071934	thiamine transmembrane transport	4.257075e-3
GO:0045656	negative regulation of monocyte differentiation	4.441990e-3
GO:0060876	semicircular canal formation	4.441990e-3
GO:2000627	positive regulation of miRNA catabolic process	4.467527e-3
GO:0071042	nuclear polyadenylation-dependent mRNA catabolic process	4.467527e-3
GO:0009048	dosage compensation, by inactivation of X chromosome	4.467527e-3
GO:0000964	mitochondrial RNA 5'-end processing	4.467527e-3
GO:0040030	regulation of molecular function, epigenetic	4.555136e-3
GO:0007126	meiosis	4.593102e-3
GO:0006362	transcription elongation from RNA polymerase I promoter	4.626744e-3
GO:0048291	isotype switching to IgG isotypes	4.751660e-3
GO:0002842	positive regulation of T cell mediated immune response to tumor cell	4.751660e-3
GO:0002368	B cell cytokine production	4.751660e-3
GO:0045040	protein import into mitochondrial outer membrane	4.757247e-3
GO:0046541	saliva secretion	4.771124e-3
GO:0007127	meiosis I	4.777408e-3
GO:0019227	neuronal action potential propagation	4.806995e-3
GO:0050792	regulation of viral reproduction	4.904332e-3
GO:0000086	G2/M transition of mitotic cell cycle	4.958926e-3
GO:0010906	regulation of glucose metabolic process	4.966529e-3
GO:0001510	RNA methylation	4.992631e-3
GO:0048515	spermatid differentiation	5.026181e-3
GO:0034660	ncRNA metabolic process	5.032614e-3
GO:0006003	fructose 2,6-bisphosphate metabolic process	5.145779e-3
GO:0023021	termination of signal transduction	5.160131e-3
GO:0007004	telomere maintenance via telomerase	5.279129e-3
GO:0007023	post-chaperonin tubulin folding pathway	5.312494e-3
GO:0048268	clathrin coat assembly	5.347689e-3
GO:0051168	nuclear export	5.397459e-3
GO:0071732	cellular response to nitric oxide	5.714120e-3
GO:0040009	regulation of growth rate	5.977356e-3
GO:0006548	histidine catabolic process	6.016299e-3
GO:0001778	plasma membrane repair	6.111350e-3
GO:0070213	protein auto-ADP-ribosylation	6.199736e-3
GO:0001696	gastric acid secretion	6.199736e-3
GO:0033692	cellular polysaccharide biosynthetic process	6.296545e-3
GO:0000237	leptotene	6.316576e-3
GO:0015739	sialic acid transport	6.316576e-3
GO:0001832	blastocyst growth	6.326419e-3
GO:0006409	tRNA export from nucleus	6.363432e-3
GO:0051289	protein homotetramerization	6.390432e-3
GO:0046626	regulation of insulin receptor signaling pathway	6.410748e-3
GO:0090162	establishment of epithelial cell polarity	6.489566e-3
GO:0006516	glycoprotein catabolic process	6.661669e-3
GO:0043666	regulation of phosphoprotein phosphatase activity	6.699986e-3
GO:0042760	very long-chain fatty acid catabolic process	6.857621e-3
GO:0034047	regulation of protein phosphatase type 2A activity	6.857621e-3
GO:0071826	ribonucleoprotein complex subunit organization	6.980696e-3
GO:0007386	compartment pattern specification	6.991485e-3
GO:0006271	DNA strand elongation involved in DNA replication	7.024854e-3
GO:0050913	sensory perception of bitter taste	7.189717e-3
GO:0035873	lactate transmembrane transport	7.514371e-3
GO:0031529	ruffle organization	7.516120e-3
GO:0051781	positive regulation of cell division	7.610053e-3
GO:0022007	convergent extension involved in neural plate elongation	7.828003e-3
GO:0000463	maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)	7.828003e-3
GO:0001833	inner cell mass cell proliferation	8.160978e-3
GO:0030913	paranodal junction assembly	8.196585e-3
GO:0006360	transcription from RNA polymerase I promoter	8.338965e-3
GO:0001574	ganglioside biosynthetic process	8.387274e-3
GO:0006048	UDP-N-acetylglucosamine biosynthetic process	8.751251e-3
GO:0001988	positive regulation of heart rate involved in baroreceptor response to decreased systemic arterial blood pressure	8.802515e-3
GO:0046467	membrane lipid biosynthetic process	8.926939e-3
GO:0043089	positive regulation of Cdc42 GTPase activity	8.933390e-3
GO:0046323	glucose import	9.126392e-3
GO:0032006	regulation of TOR signaling cascade	9.135981e-3
GO:0007263	nitric oxide mediated signal transduction	9.236753e-3
GO:0009088	threonine biosynthetic process	9.492062e-3
GO:0034637	cellular carbohydrate biosynthetic process	9.506792e-3
GO:0006047	UDP-N-acetylglucosamine metabolic process	9.971047e-3
GO:0051220	cytoplasmic sequestering of protein	9.978041e-3
GO:0048524	positive regulation of viral reproduction	1.001486e-2
GO:0070885	negative regulation of calcineurin-NFAT signaling pathway	1.005842e-2
GO:0045905	positive regulation of translational termination	1.013108e-2
GO:0006452	translational frameshifting	1.013108e-2
GO:0045901	positive regulation of translational elongation	1.013108e-2
GO:0042992	negative regulation of transcription factor import into nucleus	1.020271e-2
GO:0097152	mesenchymal cell apoptosis	1.041797e-2
GO:2001037	positive regulation of tongue muscle cell differentiation	1.041797e-2
GO:0060982	coronary artery morphogenesis	1.041797e-2
GO:0060383	positive regulation of DNA strand elongation	1.041797e-2
GO:0015986	ATP synthesis coupled proton transport	1.049851e-2
GO:0015868	purine ribonucleotide transport	1.051300e-2
GO:0046836	glycolipid transport	1.066912e-2
GO:0042982	amyloid precursor protein metabolic process	1.076413e-2
GO:0032869	cellular response to insulin stimulus	1.090058e-2
GO:0030194	positive regulation of blood coagulation	1.135749e-2
GO:0070076	histone lysine demethylation	1.147001e-2
GO:0006283	transcription-coupled nucleotide-excision repair	1.156652e-2
GO:0090305	nucleic acid phosphodiester bond hydrolysis	1.171864e-2
GO:0060044	negative regulation of cardiac muscle cell proliferation	1.217688e-2
GO:0016577	histone demethylation	1.220493e-2
GO:0046601	positive regulation of centriole replication	1.224218e-2
GO:0071048	nuclear retention of unspliced pre-mRNA at the site of transcription	1.224218e-2
GO:0043308	eosinophil degranulation	1.224218e-2
GO:0032727	positive regulation of interferon-alpha production	1.232397e-2
GO:0006370	mRNA capping	1.232769e-2
GO:0009452	RNA capping	1.233873e-2
GO:2000334	positive regulation of blood microparticle formation	1.237803e-2
GO:0042637	catagen	1.237803e-2
GO:0021592	fourth ventricle development	1.237803e-2
GO:0060427	lung connective tissue development	1.254942e-2
GO:0070267	oncosis	1.254942e-2
GO:0006438	valyl-tRNA aminoacylation	1.254942e-2
GO:2000659	regulation of interleukin-1-mediated signaling pathway	1.255396e-2
GO:0033182	regulation of histone ubiquitination	1.260328e-2
GO:0010933	positive regulation of macrophage tolerance induction	1.260328e-2
GO:0000965	mitochondrial RNA 3'-end processing	1.270629e-2
GO:0000958	mitochondrial mRNA catabolic process	1.270629e-2
GO:0000962	positive regulation of mitochondrial RNA catabolic process	1.270629e-2
GO:0000184	nuclear-transcribed mRNA catabolic process, nonsense-mediated decay	1.303930e-2
GO:0032204	regulation of telomere maintenance	1.311360e-2
GO:0043305	negative regulation of mast cell degranulation	1.311432e-2
GO:0035176	social behavior	1.338862e-2
GO:0022616	DNA strand elongation	1.352525e-2
GO:0045197	establishment or maintenance of epithelial cell apical/basal polarity	1.354051e-2
GO:0051725	protein de-ADP-ribosylation	1.356311e-2
GO:0060218	hemopoietic stem cell differentiation	1.362668e-2
GO:0030951	establishment or maintenance of microtubule cytoskeleton polarity	1.362930e-2
GO:0060458	right lung development	1.413851e-2
GO:0060335	positive regulation of interferon-gamma-mediated signaling pathway	1.419807e-2
GO:0000718	nucleotide-excision repair, DNA damage removal	1.458406e-2
GO:0006004	fucose metabolic process	1.458406e-2
GO:0060426	lung vasculature development	1.469458e-2
GO:0046349	amino sugar biosynthetic process	1.480379e-2
GO:0022417	protein maturation by protein folding	1.480379e-2
GO:0000279	M phase	1.484624e-2
GO:0021919	BMP signaling pathway involved in spinal cord dorsal/ventral patterning	1.494014e-2
GO:0072277	metanephric glomerular capillary formation	1.496291e-2
GO:0072104	glomerular capillary formation	1.522055e-2
GO:0009301	snRNA transcription	1.547128e-2
GO:0070845	polyubiquitinated misfolded protein transport	1.547128e-2
GO:0007043	cell-cell junction assembly	1.578754e-2
GO:0070863	positive regulation of protein exit from endoplasmic reticulum	1.580747e-2
GO:0042744	hydrogen peroxide catabolic process	1.589093e-2
GO:0021571	rhombomere 5 development	1.604999e-2
GO:0071281	cellular response to iron ion	1.604999e-2
GO:0001757	somite specification	1.604999e-2
GO:0045607	regulation of auditory receptor cell differentiation	1.617463e-2
GO:0050820	positive regulation of coagulation	1.622315e-2
GO:0043457	regulation of cellular respiration	1.636221e-2
GO:0032988	ribonucleoprotein complex disassembly	1.638976e-2
GO:0006547	histidine metabolic process	1.678128e-2
GO:0006921	cellular component disassembly involved in apoptosis	1.694521e-2
GO:0006301	postreplication repair	1.718114e-2
GO:0042797	tRNA transcription from RNA polymerase III promoter	1.737014e-2
GO:0042791	5S class rRNA transcription from RNA polymerase III type 1 promoter	1.737014e-2
GO:0007052	mitotic spindle organization	1.738047e-2
GO:0032057	negative regulation of translational initiation in response to stress	1.755043e-2
GO:0060112	generation of ovulation cycle rhythm	1.755043e-2
GO:0014028	notochord formation	1.755043e-2
GO:0042273	ribosomal large subunit biogenesis	1.767854e-2
GO:0043558	regulation of translational initiation in response to stress	1.791017e-2
GO:0006369	termination of RNA polymerase II transcription	1.802593e-2
GO:0032201	telomere maintenance via semi-conservative replication	1.820694e-2
GO:0050908	detection of light stimulus involved in visual perception	1.836646e-2
GO:0015931	nucleobase-containing compound transport	1.869826e-2
GO:0006862	nucleotide transport	1.883143e-2
GO:0015827	tryptophan transport	1.952700e-2
GO:0032509	endosome transport via multivesicular body sorting pathway	1.959980e-2
GO:0051973	positive regulation of telomerase activity	1.959980e-2
GO:0022027	interkinetic nuclear migration	1.978546e-2
GO:0035306	positive regulation of dephosphorylation	2.008606e-2
GO:0006270	DNA-dependent DNA replication initiation	2.008784e-2
GO:0045608	negative regulation of auditory receptor cell differentiation	2.016242e-2
GO:0061090	positive regulation of sequestering of zinc ion	2.037637e-2
GO:0045716	positive regulation of low-density lipoprotein particle receptor biosynthetic process	2.037637e-2
GO:0006413	translational initiation	2.101640e-2
GO:0051036	regulation of endosome size	2.138150e-2
GO:0006406	mRNA export from nucleus	2.152639e-2
GO:0022618	ribonucleoprotein complex assembly	2.164973e-2
GO:0021658	rhombomere 3 morphogenesis	2.224340e-2
GO:0019047	provirus integration	2.287472e-2
GO:0035089	establishment of apical/basal cell polarity	2.302550e-2
GO:0016584	nucleosome positioning	2.302550e-2
GO:0021612	facial nerve structural organization	2.306081e-2
GO:0016075	rRNA catabolic process	2.343350e-2
GO:0048496	maintenance of organ identity	2.343350e-2
GO:0048241	epinephrine transport	2.350052e-2
GO:0000959	mitochondrial RNA metabolic process	2.370810e-2
GO:0060455	negative regulation of gastric acid secretion	2.375348e-2
GO:0021914	negative regulation of smoothened signaling pathway involved in ventral spinal cord patterning	2.375348e-2
GO:0002005	angiotensin catabolic process in blood	2.375348e-2
GO:0050658	RNA transport	2.387355e-2
GO:0000387	spliceosomal snRNP assembly	2.433911e-2
GO:0034619	cellular chaperone-mediated protein complex assembly	2.456083e-2
GO:0070861	regulation of protein exit from endoplasmic reticulum	2.456083e-2
GO:0017121	phospholipid scrambling	2.456083e-2
GO:0007141	male meiosis I	2.495413e-2
GO:0071447	cellular response to hydroperoxide	2.498299e-2
GO:0071340	skeletal muscle nicotinic acetylcholine receptor clustering	2.504975e-2

GREAT analysis results for mouseGenomic Enrichment of Annotations Tool (GREAT, Nat Biotechnol. 2010 May;28(5):495-501) is used to identify, both in human and in mouse, the gene ontology terms of biological processes enriched given the predicted TFBSs, and evaluated the overlap in the top-500 gene ontology terms between human and mouse. For each novel motif, the P value for the overlap was then evaluated by calculating its relative rank with respect to this background distribution.<br>Analyst: Michiel de Hoon <br><br>link to source dataset <br>data

---

GO ID	GO Term	p-value
GO:0090086	negative regulation of protein deubiquitination	3.308601e-16
GO:0090085	regulation of protein deubiquitination	1.499734e-12
GO:0090084	negative regulation of inclusion body assembly	1.499734e-12
GO:0006412	translation	1.396305e-11
GO:0006396	RNA processing	3.922001e-11
GO:0010898	positive regulation of triglyceride catabolic process	3.864577e-10
GO:0044260	cellular macromolecule metabolic process	4.023754e-10
GO:0034470	ncRNA processing	4.864476e-10
GO:0090208	positive regulation of triglyceride metabolic process	5.323892e-10
GO:0046984	regulation of hemoglobin biosynthetic process	7.816316e-10
GO:0034660	ncRNA metabolic process	1.312557e-9
GO:0042998	positive regulation of Golgi to plasma membrane protein transport	1.440644e-9
GO:0044265	cellular macromolecule catabolic process	1.548336e-9
GO:0042254	ribosome biogenesis	1.759270e-9
GO:0051006	positive regulation of lipoprotein lipase activity	3.008889e-9
GO:0071843	cellular component biogenesis at cellular level	3.983478e-9
GO:0090083	regulation of inclusion body assembly	1.410761e-8
GO:0043632	modification-dependent macromolecule catabolic process	3.318292e-8
GO:0022613	ribonucleoprotein complex biogenesis	4.299769e-8
GO:0016071	mRNA metabolic process	4.894667e-8
GO:0010896	regulation of triglyceride catabolic process	5.772855e-8
GO:0009057	macromolecule catabolic process	7.057172e-8
GO:0010467	gene expression	8.350226e-8
GO:0006364	rRNA processing	1.082543e-7
GO:0014878	response to electrical stimulus involved in regulation of muscle adaptation	1.125419e-7
GO:0051603	proteolysis involved in cellular protein catabolic process	1.175290e-7
GO:0009956	radial pattern formation	1.208218e-7
GO:0006888	ER to Golgi vesicle-mediated transport	1.303208e-7
GO:0046985	positive regulation of hemoglobin biosynthetic process	1.327489e-7
GO:0043973	histone H3-K4 acetylation	1.327489e-7
GO:0000972	transcription-dependent tethering of RNA polymerase II gene DNA at nuclear periphery	1.327489e-7
GO:0030163	protein catabolic process	1.486833e-7
GO:0019941	modification-dependent protein catabolic process	1.995000e-7
GO:0071034	CUT catabolic process	2.303375e-7
GO:0045836	positive regulation of meiosis	2.687578e-7
GO:0016072	rRNA metabolic process	3.858982e-7
GO:0006511	ubiquitin-dependent protein catabolic process	4.009283e-7
GO:0044257	cellular protein catabolic process	4.919765e-7
GO:0006391	transcription initiation from mitochondrial promoter	4.973591e-7
GO:0002741	positive regulation of cytokine secretion involved in immune response	5.204523e-7
GO:0030262	apoptotic nuclear change	5.478160e-7
GO:0008354	germ cell migration	6.976455e-7
GO:0044237	cellular metabolic process	7.087997e-7
GO:0051299	centrosome separation	1.054857e-6
GO:0090207	regulation of triglyceride metabolic process	1.167267e-6
GO:0043170	macromolecule metabolic process	1.319643e-6
GO:0050996	positive regulation of lipid catabolic process	1.742608e-6
GO:0016068	type I hypersensitivity	1.773820e-6
GO:0010902	positive regulation of very-low-density lipoprotein particle remodeling	1.820448e-6
GO:0034445	negative regulation of plasma lipoprotein particle oxidation	1.903516e-6
GO:0045358	negative regulation of interferon-beta biosynthetic process	2.205716e-6
GO:0006921	cellular component disassembly involved in apoptosis	2.233663e-6
GO:0006654	phosphatidic acid biosynthetic process	2.404942e-6
GO:0042996	regulation of Golgi to plasma membrane protein transport	2.529037e-6
GO:0016446	somatic hypermutation of immunoglobulin genes	2.570192e-6
GO:0016073	snRNA metabolic process	2.656141e-6
GO:0034442	regulation of lipoprotein oxidation	3.244056e-6
GO:0050689	negative regulation of defense response to virus by host	3.424257e-6
GO:0006713	glucocorticoid catabolic process	3.424257e-6
GO:0043148	mitotic spindle stabilization	3.424257e-6
GO:0006513	protein monoubiquitination	3.615811e-6
GO:0071845	cellular component disassembly at cellular level	3.970148e-6
GO:0006200	ATP catabolic process	4.222266e-6
GO:0022411	cellular component disassembly	5.207212e-6
GO:2000484	positive regulation of interleukin-8 secretion	5.385209e-6
GO:0006982	response to lipid hydroperoxide	5.385209e-6
GO:0040020	regulation of meiosis	5.562375e-6
GO:0042273	ribosomal large subunit biogenesis	5.634693e-6
GO:0016926	protein desumoylation	6.416003e-6
GO:0044248	cellular catabolic process	6.980945e-6
GO:0060849	regulation of transcription involved in lymphatic endothelial cell fate commitment	7.377936e-6
GO:0006540	glutamate decarboxylation to succinate	9.047739e-6
GO:0006901	vesicle coating	9.174572e-6
GO:0002339	B cell selection	9.484593e-6
GO:0000959	mitochondrial RNA metabolic process	9.670653e-6
GO:0031331	positive regulation of cellular catabolic process	9.711210e-6
GO:0060839	endothelial cell fate commitment	1.003526e-5
GO:0008208	C21-steroid hormone catabolic process	1.036906e-5
GO:0042255	ribosome assembly	1.045229e-5
GO:0034661	ncRNA catabolic process	1.165520e-5
GO:0060836	lymphatic endothelial cell differentiation	1.165520e-5
GO:0051445	regulation of meiotic cell cycle	1.197880e-5
GO:0006415	translational termination	1.332881e-5
GO:0050748	negative regulation of lipoprotein metabolic process	1.350059e-5
GO:0044267	cellular protein metabolic process	1.612677e-5
GO:0000239	pachytene	1.631256e-5
GO:0016070	RNA metabolic process	1.830095e-5
GO:0060466	activation of meiosis involved in egg activation	1.985275e-5
GO:0016180	snRNA processing	2.066457e-5
GO:0040016	embryonic cleavage	2.155420e-5
GO:0055090	acylglycerol homeostasis	2.344120e-5
GO:0045190	isotype switching	2.494436e-5
GO:0051257	spindle midzone assembly involved in meiosis	2.576602e-5
GO:0000492	box C/D snoRNP assembly	2.576602e-5
GO:0006397	mRNA processing	2.639371e-5
GO:0060319	primitive erythrocyte differentiation	2.894430e-5
GO:0015992	proton transport	3.165563e-5
GO:0043161	proteasomal ubiquitin-dependent protein catabolic process	3.320011e-5
GO:0048268	clathrin coat assembly	3.548415e-5
GO:0002227	innate immune response in mucosa	3.804806e-5
GO:0006818	hydrogen transport	3.852218e-5
GO:0043633	polyadenylation-dependent RNA catabolic process	3.877522e-5
GO:0060975	cardioblast migration to the midline involved in heart field formation	3.877522e-5
GO:0035481	positive regulation of Notch signaling pathway involved in heart induction	3.877522e-5
GO:0003259	cardioblast anterior-lateral migration	3.877522e-5
GO:0003210	cardiac atrium formation	3.877522e-5
GO:0003236	sinus venosus morphogenesis	3.877522e-5
GO:0044238	primary metabolic process	4.217138e-5
GO:0010498	proteasomal protein catabolic process	4.552004e-5
GO:0002030	inhibitory G-protein coupled receptor phosphorylation	4.687542e-5
GO:0015931	nucleobase-containing compound transport	4.769813e-5
GO:0009207	purine ribonucleoside triphosphate catabolic process	4.796869e-5
GO:0060029	convergent extension involved in organogenesis	5.027518e-5
GO:0002381	immunoglobulin production involved in immunoglobulin mediated immune response	5.094537e-5
GO:0017183	peptidyl-diphthamide biosynthetic process from peptidyl-histidine	5.326288e-5
GO:0000910	cytokinesis	6.205641e-5
GO:0009146	purine nucleoside triphosphate catabolic process	6.289573e-5
GO:0031558	induction of apoptosis in response to chemical stimulus	6.923258e-5
GO:0048633	positive regulation of skeletal muscle tissue growth	7.004312e-5
GO:0048850	hypophysis morphogenesis	7.227035e-5
GO:0060206	estrous cycle phase	7.700953e-5
GO:0008635	activation of caspase activity by cytochrome c	7.820455e-5
GO:0010501	RNA secondary structure unwinding	7.854293e-5
GO:0042256	mature ribosome assembly	8.060252e-5
GO:0061350	planar cell polarity pathway involved in cardiac muscle tissue morphogenesis	8.254454e-5
GO:0061349	planar cell polarity pathway involved in cardiac right atrium morphogenesis	8.254454e-5
GO:0061354	planar cell polarity pathway involved in pericardium morphogenesis	8.254454e-5
GO:0060210	metestrus	8.254454e-5
GO:0061347	planar cell polarity pathway involved in outflow tract morphogenesis	8.254454e-5
GO:0061348	planar cell polarity pathway involved in ventricular septum morphogenesis	8.254454e-5
GO:0007051	spindle organization	8.477590e-5
GO:0006390	transcription from mitochondrial promoter	8.660748e-5
GO:0006298	mismatch repair	8.700339e-5
GO:0009143	nucleoside triphosphate catabolic process	8.745471e-5
GO:0019047	provirus integration	8.753456e-5
GO:0030433	ER-associated protein catabolic process	9.095891e-5
GO:0006403	RNA localization	9.182520e-5
GO:0034621	cellular macromolecular complex subunit organization	9.536498e-5
GO:0007140	male meiosis	1.000742e-4
GO:2000049	positive regulation of cell-cell adhesion mediated by cadherin	1.015577e-4
GO:0001672	regulation of chromatin assembly or disassembly	1.015577e-4
GO:0034551	mitochondrial respiratory chain complex III assembly	1.099836e-4
GO:0009154	purine ribonucleotide catabolic process	1.135565e-4
GO:0018202	peptidyl-histidine modification	1.214800e-4
GO:0044091	membrane biogenesis	1.240523e-4
GO:0051004	regulation of lipoprotein lipase activity	1.347761e-4
GO:0090304	nucleic acid metabolic process	1.394225e-4
GO:0090224	regulation of spindle organization	1.446592e-4
GO:0050994	regulation of lipid catabolic process	1.449719e-4
GO:0043060	meiotic metaphase I plate congression	1.464205e-4
GO:0030263	apoptotic chromosome condensation	1.464205e-4
GO:0002352	B cell negative selection	1.464205e-4
GO:0060067	cervix development	1.505034e-4
GO:0007005	mitochondrion organization	1.505526e-4
GO:0022614	membrane to membrane docking	1.557182e-4
GO:0043928	exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay	1.653250e-4
GO:0019428	allantoin biosynthetic process	1.693865e-4
GO:0043687	post-translational protein modification	1.723741e-4
GO:0009261	ribonucleotide catabolic process	1.739385e-4
GO:0043624	cellular protein complex disassembly	1.763973e-4
GO:0016567	protein ubiquitination	1.777850e-4
GO:0022406	membrane docking	1.787381e-4
GO:0007343	egg activation	1.941515e-4
GO:0072148	epithelial cell fate commitment	1.977976e-4
GO:0003344	pericardium morphogenesis	1.990677e-4
GO:0048841	regulation of axon extension involved in axon guidance	2.027838e-4
GO:0060599	lateral sprouting involved in mammary gland duct morphogenesis	2.173856e-4
GO:0031167	rRNA methylation	2.173856e-4
GO:0021702	cerebellar Purkinje cell differentiation	2.201762e-4
GO:0060921	sinoatrial node cell differentiation	2.320714e-4
GO:0060340	positive regulation of type I interferon-mediated signaling pathway	2.320714e-4
GO:0009056	catabolic process	2.326491e-4
GO:0050658	RNA transport	2.338932e-4
GO:0001945	lymph vessel development	2.369438e-4
GO:0034421	post-translational protein acetylation	2.396465e-4
GO:0002541	activation of plasma proteins involved in acute inflammatory response	2.396465e-4
GO:0045950	negative regulation of mitotic recombination	2.539217e-4
GO:0060125	negative regulation of growth hormone secretion	2.628035e-4
GO:0051463	negative regulation of cortisol secretion	2.628035e-4
GO:0009443	pyridoxal 5'-phosphate salvage	2.628035e-4
GO:0017055	negative regulation of RNA polymerase II transcriptional preinitiation complex assembly	2.694874e-4
GO:0009896	positive regulation of catabolic process	2.820690e-4
GO:0006139	nucleobase-containing compound metabolic process	3.043662e-4
GO:0043241	protein complex disassembly	3.074523e-4
GO:0006900	membrane budding	3.095427e-4
GO:0050746	regulation of lipoprotein metabolic process	3.239991e-4
GO:0060236	regulation of mitotic spindle organization	3.269009e-4
GO:0051255	spindle midzone assembly	3.269009e-4
GO:0035093	spermatogenesis, exchange of chromosomal proteins	3.269009e-4
GO:0051321	meiotic cell cycle	3.274113e-4
GO:0060026	convergent extension	3.279141e-4
GO:0010669	epithelial structure maintenance	3.358947e-4
GO:0048610	cellular process involved in reproduction	3.413672e-4
GO:0090037	positive regulation of protein kinase C signaling cascade	3.593651e-4
GO:0006265	DNA topological change	3.617238e-4
GO:0007159	leukocyte cell-cell adhesion	3.707849e-4
GO:0015747	urate transport	3.801726e-4
GO:0051310	metaphase plate congression	4.044631e-4
GO:0070562	regulation of vitamin D receptor signaling pathway	4.153300e-4
GO:0007060	male meiosis chromosome segregation	4.153300e-4
GO:0009082	branched chain family amino acid biosynthetic process	4.243083e-4
GO:0022403	cell cycle phase	4.465362e-4
GO:0008380	RNA splicing	4.627626e-4
GO:0097029	mature dendritic cell differentiation	4.757746e-4
GO:0070368	positive regulation of hepatocyte differentiation	4.757746e-4
GO:0042664	negative regulation of endodermal cell fate specification	4.757746e-4
GO:0000154	rRNA modification	4.954033e-4
GO:2000401	regulation of lymphocyte migration	5.142886e-4
GO:0000019	regulation of mitotic recombination	5.213635e-4
GO:0001502	cartilage condensation	5.429834e-4
GO:0043623	cellular protein complex assembly	5.556206e-4
GO:0015986	ATP synthesis coupled proton transport	5.582659e-4
GO:0014911	positive regulation of smooth muscle cell migration	5.672681e-4
GO:0006414	translational elongation	5.725813e-4
GO:0008299	isoprenoid biosynthetic process	6.015587e-4
GO:0003163	sinoatrial node development	6.136116e-4
GO:0007035	vacuolar acidification	6.171864e-4
GO:0008152	metabolic process	6.361484e-4
GO:0071048	nuclear retention of unspliced pre-mRNA at the site of transcription	6.369688e-4
GO:0002368	B cell cytokine production	6.369688e-4
GO:0072643	interferon-gamma secretion	6.369688e-4
GO:0090198	negative regulation of chemokine secretion	6.369688e-4
GO:0071035	nuclear polyadenylation-dependent rRNA catabolic process	6.369688e-4
GO:0072608	interleukin-10 secretion	6.369688e-4
GO:0070963	positive regulation of neutrophil mediated killing of gram-negative bacterium	6.369688e-4
GO:0035926	chemokine (C-C motif) ligand 2 secretion	6.369688e-4
GO:0043311	positive regulation of eosinophil degranulation	6.369688e-4
GO:0048291	isotype switching to IgG isotypes	6.369688e-4
GO:0048597	post-embryonic camera-type eye morphogenesis	6.472952e-4
GO:0002036	regulation of L-glutamate transport	6.472952e-4
GO:0048496	maintenance of organ identity	6.538180e-4
GO:0002827	positive regulation of T-helper 1 type immune response	6.694472e-4
GO:0060920	pacemaker cell differentiation	6.960256e-4
GO:0000712	resolution of meiotic recombination intermediates	6.960256e-4
GO:0010390	histone monoubiquitination	7.153999e-4
GO:0000237	leptotene	7.234828e-4
GO:0032446	protein modification by small protein conjugation	7.245673e-4
GO:0016447	somatic recombination of immunoglobulin gene segments	7.638519e-4
GO:0071476	cellular hypotonic response	7.955518e-4
GO:0048631	regulation of skeletal muscle tissue growth	8.095591e-4
GO:0016557	peroxisome membrane biogenesis	8.095591e-4
GO:0007089	traversing start control point of mitotic cell cycle	8.095591e-4
GO:0070301	cellular response to hydrogen peroxide	8.149966e-4
GO:0034641	cellular nitrogen compound metabolic process	8.194344e-4
GO:0002739	regulation of cytokine secretion involved in immune response	8.290909e-4
GO:0051303	establishment of chromosome localization	8.584154e-4
GO:0022618	ribonucleoprotein complex assembly	8.792164e-4
GO:0060068	vagina development	8.947920e-4
GO:0032594	protein transport within lipid bilayer	9.097104e-4
GO:0070647	protein modification by small protein conjugation or removal	9.100706e-4
GO:0010891	negative regulation of sequestering of triglyceride	9.267367e-4
GO:0015827	tryptophan transport	9.686855e-4
GO:0070059	apoptosis in response to endoplasmic reticulum stress	9.954811e-4
GO:0051307	meiotic chromosome separation	9.988860e-4
GO:0006195	purine nucleotide catabolic process	1.021553e-3
GO:0019287	isopentenyl diphosphate biosynthetic process, mevalonate pathway	1.050203e-3
GO:0010825	positive regulation of centrosome duplication	1.050203e-3
GO:0000073	spindle pole body separation	1.050203e-3
GO:0003241	growth involved in heart morphogenesis	1.050203e-3
GO:0032729	positive regulation of interferon-gamma production	1.055171e-3
GO:0000212	meiotic spindle organization	1.064195e-3
GO:0043570	maintenance of DNA repeat elements	1.120772e-3
GO:0043123	positive regulation of I-kappaB kinase/NF-kappaB cascade	1.147037e-3
GO:0051028	mRNA transport	1.194409e-3
GO:0061338	atrioventricular node impulse conduction delay	1.210755e-3
GO:0045090	retroviral genome replication	1.235162e-3
GO:2000653	regulation of genetic imprinting	1.235162e-3
GO:0048773	erythrophore differentiation	1.235162e-3
GO:0034021	response to silicon dioxide	1.235162e-3
GO:0003069	vasodilation by acetylcholine involved in regulation of systemic arterial blood pressure	1.235162e-3
GO:0001315	age-dependent response to reactive oxygen species	1.235162e-3
GO:0061003	positive regulation of dendritic spine morphogenesis	1.238538e-3
GO:0007281	germ cell development	1.259227e-3
GO:0090179	planar cell polarity pathway involved in neural tube closure	1.259948e-3
GO:0016032	viral reproduction	1.277298e-3
GO:0032423	regulation of mismatch repair	1.307407e-3
GO:0048843	negative regulation of axon extension involved in axon guidance	1.315415e-3
GO:0071712	ER-associated misfolded protein catabolic process	1.323579e-3
GO:0031146	SCF-dependent proteasomal ubiquitin-dependent protein catabolic process	1.351500e-3
GO:0001777	T cell homeostatic proliferation	1.468078e-3
GO:0071286	cellular response to magnesium ion	1.480562e-3
GO:0007099	centriole replication	1.480562e-3
GO:0016445	somatic diversification of immunoglobulins	1.501410e-3
GO:0022402	cell cycle process	1.533245e-3
GO:0009166	nucleotide catabolic process	1.548548e-3
GO:0045080	positive regulation of chemokine biosynthetic process	1.571800e-3
GO:0006515	misfolded or incompletely synthesized protein catabolic process	1.653702e-3
GO:0090267	positive regulation of mitotic cell cycle spindle assembly checkpoint	1.655696e-3
GO:0006807	nitrogen compound metabolic process	1.660547e-3
GO:0071951	conversion of methionyl-tRNA to N-formyl-methionyl-tRNA	1.662608e-3
GO:0046902	regulation of mitochondrial membrane permeability	1.667777e-3
GO:0042136	neurotransmitter biosynthetic process	1.671405e-3
GO:0006448	regulation of translational elongation	1.671405e-3
GO:0090129	positive regulation of synapse maturation	1.713144e-3
GO:0071826	ribonucleoprotein complex subunit organization	1.779963e-3
GO:0044029	hypomethylation of CpG island	1.811642e-3
GO:0031123	RNA 3'-end processing	1.826525e-3
GO:0007127	meiosis I	1.839540e-3
GO:0046498	S-adenosylhomocysteine metabolic process	1.849709e-3
GO:0006308	DNA catabolic process	1.876011e-3
GO:0010803	regulation of tumor necrosis factor-mediated signaling pathway	1.898130e-3
GO:0006538	glutamate catabolic process	1.898130e-3
GO:2000426	negative regulation of apoptotic cell clearance	1.964964e-3
GO:0017004	cytochrome complex assembly	1.964964e-3
GO:0090082	positive regulation of heart induction by negative regulation of canonical Wnt receptor signaling pathway	1.989179e-3
GO:0045046	protein import into peroxisome membrane	2.045078e-3
GO:0006122	mitochondrial electron transport, ubiquinol to cytochrome c	2.045078e-3
GO:0046986	negative regulation of hemoglobin biosynthetic process	2.095883e-3
GO:0035494	SNARE complex disassembly	2.095883e-3
GO:0071028	nuclear mRNA surveillance	2.095883e-3
GO:0010826	negative regulation of centrosome duplication	2.095883e-3
GO:0034137	positive regulation of toll-like receptor 2 signaling pathway	2.095883e-3
GO:0010807	regulation of synaptic vesicle priming	2.095883e-3
GO:0071294	cellular response to zinc ion	2.111140e-3
GO:0045948	positive regulation of translational initiation	2.111140e-3
GO:0035518	histone H2A monoubiquitination	2.126608e-3
GO:0007635	chemosensory behavior	2.127974e-3
GO:0003306	Wnt receptor signaling pathway involved in heart development	2.127974e-3
GO:0016574	histone ubiquitination	2.157463e-3
GO:0000303	response to superoxide	2.162490e-3
GO:0007126	meiosis	2.167803e-3
GO:0010976	positive regulation of neuron projection development	2.186550e-3
GO:0009059	macromolecule biosynthetic process	2.199323e-3
GO:0006808	regulation of nitrogen utilization	2.304562e-3
GO:0072523	purine-containing compound catabolic process	2.336720e-3
GO:0015851	nucleobase transport	2.362627e-3
GO:0042375	quinone cofactor metabolic process	2.424095e-3
GO:0006309	DNA fragmentation involved in apoptotic nuclear change	2.425404e-3
GO:0070830	tight junction assembly	2.451972e-3
GO:0046907	intracellular transport	2.473533e-3
GO:0034614	cellular response to reactive oxygen species	2.514079e-3
GO:0006402	mRNA catabolic process	2.557095e-3
GO:0032222	regulation of synaptic transmission, cholinergic	2.636983e-3
GO:0046686	response to cadmium ion	2.673150e-3
GO:0021993	initiation of neural tube closure	2.686492e-3
GO:0021571	rhombomere 5 development	2.686492e-3
GO:0032060	bleb assembly	2.801624e-3
GO:0035234	germ cell programmed cell death	2.801624e-3
GO:0030953	astral microtubule organization	2.801624e-3
GO:0010564	regulation of cell cycle process	3.004016e-3
GO:0043201	response to leucine	3.017704e-3
GO:0044240	multicellular organismal lipid catabolic process	3.019170e-3
GO:0002385	mucosal immune response	3.044185e-3
GO:0007131	reciprocal meiotic recombination	3.191212e-3
GO:0055108	Golgi to transport vesicle transport	3.251781e-3
GO:0070839	divalent metal ion export	3.251781e-3
GO:0045342	MHC class II biosynthetic process	3.251781e-3
GO:0032632	interleukin-3 production	3.251781e-3
GO:0006876	cellular cadmium ion homeostasis	3.251781e-3
GO:0015707	nitrite transport	3.251781e-3
GO:0043091	L-arginine import	3.251781e-3
GO:0042661	regulation of mesodermal cell fate specification	3.259870e-3
GO:0061337	cardiac conduction	3.499656e-3
GO:0000226	microtubule cytoskeleton organization	3.563231e-3
GO:0048539	bone marrow development	3.590072e-3
GO:0021612	facial nerve structural organization	3.590072e-3
GO:0003323	type B pancreatic cell development	3.611264e-3
GO:0010587	miRNA catabolic process	3.612071e-3
GO:0050901	leukocyte tethering or rolling	3.691483e-3
GO:0071542	dopaminergic neuron differentiation	3.750978e-3
GO:0035308	negative regulation of protein dephosphorylation	3.750978e-3
GO:0034645	cellular macromolecule biosynthetic process	3.827779e-3
GO:0008624	induction of apoptosis by extracellular signals	3.840346e-3
GO:0007128	meiotic prophase I	3.896195e-3
GO:0060686	negative regulation of prostatic bud formation	3.991246e-3
GO:0042133	neurotransmitter metabolic process	4.005559e-3
GO:0002251	organ or tissue specific immune response	4.008509e-3
GO:0021680	cerebellar Purkinje cell layer development	4.028100e-3
GO:0015991	ATP hydrolysis coupled proton transport	4.028100e-3
GO:0000288	nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay	4.028100e-3
GO:0007090	regulation of S phase of mitotic cell cycle	4.036192e-3
GO:0090128	regulation of synapse maturation	4.066385e-3
GO:0021891	olfactory bulb interneuron development	4.184988e-3
GO:0009065	glutamine family amino acid catabolic process	4.284307e-3
GO:0051881	regulation of mitochondrial membrane potential	4.284307e-3
GO:2000117	negative regulation of cysteine-type endopeptidase activity	4.285884e-3
GO:0043402	glucocorticoid mediated signaling pathway	4.285884e-3
GO:0032425	positive regulation of mismatch repair	4.285884e-3
GO:0030264	nuclear fragmentation involved in apoptotic nuclear change	4.288823e-3
GO:0006481	C-terminal protein methylation	4.288823e-3
GO:0030641	regulation of cellular pH	4.306577e-3
GO:0000279	M phase	4.357025e-3
GO:0007049	cell cycle	4.363320e-3
GO:0060215	primitive hemopoiesis	4.368764e-3
GO:0051964	negative regulation of synapse assembly	4.401314e-3
GO:0048871	multicellular organismal homeostasis	4.614223e-3
GO:0060850	regulation of transcription involved in cell fate commitment	4.635607e-3
GO:0022027	interkinetic nuclear migration	4.673191e-3
GO:0070885	negative regulation of calcineurin-NFAT signaling pathway	4.730165e-3
GO:0071025	RNA surveillance	4.730165e-3
GO:0035090	maintenance of apical/basal cell polarity	4.730165e-3
GO:0001980	regulation of systemic arterial blood pressure by ischemic conditions	4.730165e-3
GO:0051315	attachment of spindle microtubules to kinetochore involved in mitotic sister chromatid segregation	4.730165e-3
GO:0070407	oxidation-dependent protein catabolic process	4.852280e-3
GO:0010266	response to vitamin B1	4.852280e-3
GO:0006863	purine base transport	4.996541e-3
GO:0045898	regulation of RNA polymerase II transcriptional preinitiation complex assembly	5.026993e-3
GO:0010820	positive regulation of T cell chemotaxis	5.026993e-3
GO:0000305	response to oxygen radical	5.106162e-3
GO:0046034	ATP metabolic process	5.132028e-3
GO:0051225	spindle assembly	5.140061e-3
GO:0051961	negative regulation of nervous system development	5.317802e-3
GO:0033627	cell adhesion mediated by integrin	5.317802e-3
GO:0015824	proline transport	5.317802e-3
GO:0032928	regulation of superoxide anion generation	5.317802e-3
GO:0097028	dendritic cell differentiation	5.337863e-3
GO:0071477	cellular hypotonic salinity response	5.337863e-3
GO:0048842	positive regulation of axon extension involved in axon guidance	5.337863e-3
GO:0006669	sphinganine-1-phosphate biosynthetic process	5.337863e-3
GO:0042373	vitamin K metabolic process	5.337863e-3
GO:0051096	positive regulation of helicase activity	5.343436e-3
GO:0061034	olfactory bulb mitral cell layer development	5.343436e-3
GO:0033631	cell-cell adhesion mediated by integrin	5.343436e-3
GO:0006288	base-excision repair, DNA ligation	5.343436e-3
GO:0042699	follicle-stimulating hormone signaling pathway	5.343436e-3
GO:2000406	positive regulation of T cell migration	5.384255e-3
GO:0010458	exit from mitosis	5.557931e-3
GO:0018410	C-terminal protein amino acid modification	5.557931e-3
GO:0090305	nucleic acid phosphodiester bond hydrolysis	5.595098e-3
GO:0007006	mitochondrial membrane organization	5.647916e-3
GO:0032700	negative regulation of interleukin-17 production	5.734173e-3
GO:0042921	glucocorticoid receptor signaling pathway	5.761238e-3
GO:0010901	regulation of very-low-density lipoprotein particle remodeling	5.761238e-3
GO:0060632	regulation of microtubule-based movement	5.827316e-3
GO:0014889	muscle atrophy	5.849127e-3
GO:0034599	cellular response to oxidative stress	5.851651e-3
GO:0006449	regulation of translational termination	5.893811e-3
GO:0001894	tissue homeostasis	5.927222e-3
GO:0032886	regulation of microtubule-based process	5.963831e-3
GO:0002440	production of molecular mediator of immune response	5.983619e-3
GO:0051402	neuron apoptosis	6.040343e-3
GO:0045819	positive regulation of glycogen catabolic process	6.047133e-3
GO:0035092	sperm chromatin condensation	6.047133e-3
GO:0032274	gonadotropin secretion	6.116701e-3
GO:0034372	very-low-density lipoprotein particle remodeling	6.158675e-3
GO:0070265	necrotic cell death	6.165199e-3
GO:0051168	nuclear export	6.165738e-3
GO:0045136	development of secondary sexual characteristics	6.199703e-3
GO:0006401	RNA catabolic process	6.251493e-3
GO:0003161	cardiac conduction system development	6.274021e-3
GO:0046700	heterocycle catabolic process	6.295857e-3
GO:0033574	response to testosterone stimulus	6.416417e-3
GO:0006406	mRNA export from nucleus	6.490527e-3
GO:0045112	integrin biosynthetic process	6.545410e-3
GO:0000105	histidine biosynthetic process	6.545410e-3
GO:0070267	oncosis	6.553476e-3
GO:0043309	regulation of eosinophil degranulation	6.553476e-3
GO:0009150	purine ribonucleotide metabolic process	6.564350e-3
GO:0010824	regulation of centrosome duplication	6.722145e-3
GO:0070544	histone H3-K36 demethylation	6.722145e-3
GO:0002377	immunoglobulin production	6.722597e-3
GO:0045723	positive regulation of fatty acid biosynthetic process	6.805928e-3
GO:0051169	nuclear transport	6.964234e-3
GO:0060071	Wnt receptor signaling pathway, planar cell polarity pathway	7.017874e-3
GO:0045333	cellular respiration	7.067190e-3
GO:0001961	positive regulation of cytokine-mediated signaling pathway	7.243678e-3
GO:0070925	organelle assembly	7.442777e-3
GO:0046889	positive regulation of lipid biosynthetic process	7.545516e-3
GO:0071044	histone mRNA catabolic process	7.579793e-3
GO:0000289	nuclear-transcribed mRNA poly(A) tail shortening	7.579793e-3
GO:0002344	B cell affinity maturation	7.653029e-3
GO:0010641	positive regulation of platelet-derived growth factor receptor signaling pathway	7.884532e-3
GO:0006189	'de novo' IMP biosynthetic process	7.920937e-3
GO:0006083	acetate metabolic process	7.920937e-3
GO:0043297	apical junction assembly	7.954349e-3
GO:0009205	purine ribonucleoside triphosphate metabolic process	7.987648e-3
GO:0043280	positive regulation of caspase activity	8.249999e-3
GO:0006099	tricarboxylic acid cycle	8.278129e-3
GO:0001843	neural tube closure	8.343853e-3
GO:0009199	ribonucleoside triphosphate metabolic process	8.395049e-3
GO:0060249	anatomical structure homeostasis	8.439142e-3
GO:0048852	diencephalon morphogenesis	8.442284e-3
GO:0071316	cellular response to nicotine	8.561697e-3
GO:0051095	regulation of helicase activity	8.561697e-3
GO:0048050	post-embryonic eye morphogenesis	8.561697e-3
GO:0035083	cilium axoneme assembly	8.739723e-3
GO:0009450	gamma-aminobutyric acid catabolic process	8.739723e-3
GO:0010952	positive regulation of peptidase activity	8.871610e-3
GO:0060712	spongiotrophoblast layer development	8.950605e-3
GO:0006119	oxidative phosphorylation	9.014755e-3
GO:0019538	protein metabolic process	9.048248e-3
GO:0061014	positive regulation of mRNA catabolic process	9.084009e-3
GO:0060762	regulation of branching involved in mammary gland duct morphogenesis	9.084009e-3
GO:0009086	methionine biosynthetic process	9.084009e-3
GO:0060338	regulation of type I interferon-mediated signaling pathway	9.084009e-3
GO:0045910	negative regulation of DNA recombination	9.173096e-3
GO:0030516	regulation of axon extension	9.317714e-3
GO:0010793	regulation of mRNA export from nucleus	9.441756e-3
GO:0051586	positive regulation of dopamine uptake	9.473257e-3
GO:0032613	interleukin-10 production	9.473257e-3
GO:0006450	regulation of translational fidelity	9.473257e-3
GO:0001702	gastrulation with mouth forming second	9.494071e-3
GO:0051029	rRNA transport	9.545093e-3
GO:2000425	regulation of apoptotic cell clearance	9.545093e-3
GO:0042520	positive regulation of tyrosine phosphorylation of Stat4 protein	9.545093e-3
GO:0045073	regulation of chemokine biosynthetic process	9.576478e-3
GO:0006405	RNA export from nucleus	9.700754e-3
GO:0045736	negative regulation of cyclin-dependent protein kinase activity	9.705683e-3
GO:0006310	DNA recombination	9.890406e-3
GO:0021697	cerebellar cortex formation	9.902432e-3