Novel motif:70

name:	motif70_MAATCGC

Association to promoter expression in human samples<b>Summary:</b>Significance of the correlation with CAGE expression, human <br><b>Analyst:</b> Michiel de Hoon<br><br>link to source dataset <br>data

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Association to promoter expression in mouse samples <b>Summary:</b>Significance of the correlation with CAGE expression, mouse <br><b>Analyst:</b> Michiel de Hoon<br><br>link to source dataset <br>data

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GREAT analysis results for human <b>Summary:</b>Genomic Enrichment of Annotations Tool (GREAT, Nat Biotechnol. 2010 May;28(5):495-501) is used to identify, both in human and in mouse, the gene ontology terms of biological processes enriched given the predicted TFBSs, and evaluated the overlap in the top-500 gene ontology terms between human and mouse. For each novel motif, the P value for the overlap was then evaluated by calculating its relative rank with respect to this background distribution.<br>Analyst: Michiel de Hoon<br><br>link to source dataset <br>data

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GO ID	GO Term	p-value
GO:0090304	nucleic acid metabolic process	4.035764e-13
GO:0046755	non-lytic virus budding	9.082867e-12
GO:0006302	double-strand break repair	2.892207e-11
GO:0006313	transposition, DNA-mediated	3.249451e-10
GO:0006103	2-oxoglutarate metabolic process	1.002081e-9
GO:0016070	RNA metabolic process	1.016977e-8
GO:0031503	protein complex localization	1.128223e-8
GO:0010467	gene expression	1.905840e-8
GO:0033566	gamma-tubulin complex localization	4.414252e-8
GO:0032774	RNA biosynthetic process	5.775564e-8
GO:0034629	cellular protein complex localization	7.816715e-8
GO:0006139	nucleobase-containing compound metabolic process	7.966447e-8
GO:0051321	meiotic cell cycle	1.352623e-7
GO:0048291	isotype switching to IgG isotypes	2.239522e-7
GO:0009436	glyoxylate catabolic process	2.239522e-7
GO:0002368	B cell cytokine production	2.239522e-7
GO:0002842	positive regulation of T cell mediated immune response to tumor cell	2.239522e-7
GO:0006457	protein folding	2.795545e-7
GO:0044260	cellular macromolecule metabolic process	2.866908e-7
GO:0070669	response to interleukin-2	3.043525e-7
GO:0034641	cellular nitrogen compound metabolic process	3.073457e-7
GO:0006807	nitrogen compound metabolic process	3.341484e-7
GO:0060849	regulation of transcription involved in lymphatic endothelial cell fate commitment	3.385754e-7
GO:0090118	receptor-mediated endocytosis of low-density lipoprotein particle involved in cholesterol transport	3.438300e-7
GO:0006351	transcription, DNA-dependent	3.706294e-7
GO:0000416	positive regulation of histone H3-K36 methylation	4.412405e-7
GO:0060839	endothelial cell fate commitment	5.868278e-7
GO:0019067	viral assembly, maturation, egress, and release	6.039635e-7
GO:2000162	negative regulation of planar cell polarity pathway involved in cardiac right atrium morphogenesis	9.021501e-7
GO:2000168	negative regulation of planar cell polarity pathway involved in neural tube closure	9.021501e-7
GO:2000166	negative regulation of planar cell polarity pathway involved in pericardium morphogenesis	9.021501e-7
GO:2000164	negative regulation of planar cell polarity pathway involved in outflow tract morphogenesis	9.021501e-7
GO:2000151	negative regulation of planar cell polarity pathway involved in cardiac muscle tissue morphogenesis	9.021501e-7
GO:2000055	positive regulation of Wnt receptor signaling pathway involved in dorsal/ventral axis specification	9.021501e-7
GO:0061310	canonical Wnt receptor signaling pathway involved in cardiac neural crest cell differentiation involved in heart development	9.021501e-7
GO:2000149	negative regulation of planar cell polarity pathway involved in ventricular septum morphogenesis	9.021501e-7
GO:0006657	CDP-choline pathway	1.019237e-6
GO:0016579	protein deubiquitination	1.170502e-6
GO:0090245	axis elongation involved in somitogenesis	1.328838e-6
GO:0021874	Wnt receptor signaling pathway involved in forebrain neuroblast division	1.328838e-6
GO:0070536	protein K63-linked deubiquitination	1.336632e-6
GO:0002711	positive regulation of T cell mediated immunity	1.388583e-6
GO:0060850	regulation of transcription involved in cell fate commitment	1.640488e-6
GO:0044332	Wnt receptor signaling pathway involved in dorsal/ventral axis specification	1.887674e-6
GO:0044335	canonical Wnt receptor signaling pathway involved in neural crest cell differentiation	1.907162e-6
GO:0009785	blue light signaling pathway	1.950494e-6
GO:0000723	telomere maintenance	1.965626e-6
GO:0007126	meiosis	2.428475e-6
GO:0051320	S phase	2.429148e-6
GO:2000053	regulation of Wnt receptor signaling pathway involved in dorsal/ventral axis specification	2.520625e-6
GO:0070535	histone H2A K63-linked ubiquitination	2.950650e-6
GO:0014020	primary neural tube formation	3.323265e-6
GO:0010172	embryonic body morphogenesis	3.704317e-6
GO:0045736	negative regulation of cyclin-dependent protein kinase activity	3.799450e-6
GO:0021570	rhombomere 4 development	4.260223e-6
GO:0008334	histone mRNA metabolic process	4.271910e-6
GO:0001843	neural tube closure	4.323005e-6
GO:0060836	lymphatic endothelial cell differentiation	4.356564e-6
GO:0006303	double-strand break repair via nonhomologous end joining	4.356564e-6
GO:0060606	tube closure	5.389138e-6
GO:0051289	protein homotetramerization	6.179725e-6
GO:0010719	negative regulation of epithelial to mesenchymal transition	6.417934e-6
GO:0072148	epithelial cell fate commitment	6.609773e-6
GO:0006529	asparagine biosynthetic process	7.199349e-6
GO:0006259	DNA metabolic process	8.010935e-6
GO:0032200	telomere organization	8.161613e-6
GO:0000236	mitotic prometaphase	8.863400e-6
GO:0060397	JAK-STAT cascade involved in growth hormone signaling pathway	1.055374e-5
GO:0002011	morphogenesis of an epithelial sheet	1.056384e-5
GO:0060691	epithelial cell maturation involved in salivary gland development	1.060984e-5
GO:0070086	ubiquitin-dependent endocytosis	1.060984e-5
GO:0060096	serotonin secretion, neurotransmission	1.060984e-5
GO:0060236	regulation of mitotic spindle organization	1.109651e-5
GO:0009637	response to blue light	1.109651e-5
GO:0045008	depyrimidination	1.124603e-5
GO:0000079	regulation of cyclin-dependent protein kinase activity	1.236372e-5
GO:0006310	DNA recombination	1.295822e-5
GO:0071639	positive regulation of monocyte chemotactic protein-1 production	1.405397e-5
GO:0046544	development of secondary male sexual characteristics	1.507806e-5
GO:0071044	histone mRNA catabolic process	1.789540e-5
GO:2000351	regulation of endothelial cell apoptosis	1.792078e-5
GO:0070646	protein modification by small protein removal	2.055229e-5
GO:0043170	macromolecule metabolic process	2.392863e-5
GO:0006919	activation of caspase activity	2.475676e-5
GO:0070059	apoptosis in response to endoplasmic reticulum stress	2.486371e-5
GO:0014029	neural crest formation	2.685441e-5
GO:0071637	regulation of monocyte chemotactic protein-1 production	2.918222e-5
GO:0032663	regulation of interleukin-2 production	2.948315e-5
GO:0019919	peptidyl-arginine methylation, to asymmetrical-dimethyl arginine	3.371801e-5
GO:0060980	cell migration involved in coronary vasculogenesis	3.418976e-5
GO:0046674	induction of retinal programmed cell death	3.719662e-5
GO:0048597	post-embryonic camera-type eye morphogenesis	3.719662e-5
GO:0032976	release of matrix enzymes from mitochondria	3.719662e-5
GO:0002352	B cell negative selection	3.719662e-5
GO:0001777	T cell homeostatic proliferation	3.719662e-5
GO:0006101	citrate metabolic process	3.818717e-5
GO:0002339	B cell selection	3.828224e-5
GO:0043162	ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway	4.163530e-5
GO:0021612	facial nerve structural organization	4.313522e-5
GO:0051594	detection of glucose	4.549787e-5
GO:0003281	ventricular septum development	4.961920e-5
GO:0007091	mitotic metaphase/anaphase transition	5.463881e-5
GO:0021510	spinal cord development	5.469388e-5
GO:0071887	leukocyte apoptosis	5.787052e-5
GO:0090394	negative regulation of excitatory postsynaptic membrane potential	5.849247e-5
GO:0006281	DNA repair	6.037342e-5
GO:0009223	pyrimidine deoxyribonucleotide catabolic process	6.130124e-5
GO:0060379	cardiac muscle cell myoblast differentiation	6.467396e-5
GO:0010771	negative regulation of cell morphogenesis involved in differentiation	6.486231e-5
GO:0042026	protein refolding	6.699838e-5
GO:0044237	cellular metabolic process	7.174048e-5
GO:0033127	regulation of histone phosphorylation	8.053025e-5
GO:0000279	M phase	8.129894e-5
GO:0003279	cardiac septum development	8.540265e-5
GO:0009886	post-embryonic morphogenesis	8.554066e-5
GO:0006235	dTTP biosynthetic process	8.626338e-5
GO:0002708	positive regulation of lymphocyte mediated immunity	9.032757e-5
GO:0072229	metanephric proximal convoluted tubule development	9.151941e-5
GO:0046670	positive regulation of retinal cell programmed cell death	9.151941e-5
GO:0046449	creatinine metabolic process	9.501579e-5
GO:0021915	neural tube development	9.596589e-5
GO:0007144	female meiosis I	1.006305e-4
GO:0035176	social behavior	1.133883e-4
GO:2000124	regulation of endocannabinoid signaling pathway	1.169045e-4
GO:0006102	isocitrate metabolic process	1.169045e-4
GO:0006552	leucine catabolic process	1.179597e-4
GO:0000726	non-recombinational repair	1.279028e-4
GO:0090129	positive regulation of synapse maturation	1.311508e-4
GO:0035065	regulation of histone acetylation	1.315921e-4
GO:0021794	thalamus development	1.420102e-4
GO:0070164	negative regulation of adiponectin secretion	1.516771e-4
GO:0035505	positive regulation of myosin light chain kinase activity	1.516771e-4
GO:0060355	positive regulation of cell adhesion molecule production	1.516771e-4
GO:0006244	pyrimidine nucleotide catabolic process	1.574140e-4
GO:0045086	positive regulation of interleukin-2 biosynthetic process	1.581556e-4
GO:0001783	B cell apoptosis	1.596819e-4
GO:0021546	rhombomere development	1.618971e-4
GO:0021569	rhombomere 3 development	1.732395e-4
GO:0019530	taurine metabolic process	1.732395e-4
GO:0010833	telomere maintenance via telomere lengthening	1.770635e-4
GO:0015936	coenzyme A metabolic process	1.774239e-4
GO:0009219	pyrimidine deoxyribonucleotide metabolic process	1.800137e-4
GO:0021512	spinal cord anterior/posterior patterning	1.801443e-4
GO:0021532	neural tube patterning	1.843378e-4
GO:0019368	fatty acid elongation, unsaturated fatty acid	1.903493e-4
GO:0032725	positive regulation of granulocyte macrophage colony-stimulating factor production	1.972272e-4
GO:0046676	negative regulation of insulin secretion	1.980364e-4
GO:0006479	protein methylation	1.993486e-4
GO:0032367	intracellular cholesterol transport	2.019417e-4
GO:0090128	regulation of synapse maturation	2.025250e-4
GO:0001522	pseudouridine synthesis	2.025250e-4
GO:0006285	base-excision repair, AP site formation	2.088220e-4
GO:0070163	regulation of adiponectin secretion	2.088258e-4
GO:0003218	cardiac left ventricle formation	2.122776e-4
GO:0034645	cellular macromolecule biosynthetic process	2.132323e-4
GO:0090291	negative regulation of osteoclast proliferation	2.137329e-4
GO:2000349	negative regulation of CD40 signaling pathway	2.137329e-4
GO:0072573	tolerance induction to lipopolysaccharide	2.137329e-4
GO:2000347	positive regulation of hepatocyte proliferation	2.137329e-4
GO:0034148	negative regulation of toll-like receptor 5 signaling pathway	2.137329e-4
GO:0070429	negative regulation of nucleotide-binding oligomerization domain containing 1 signaling pathway	2.137329e-4
GO:0070433	negative regulation of nucleotide-binding oligomerization domain containing 2 signaling pathway	2.137329e-4
GO:0045931	positive regulation of mitotic cell cycle	2.188438e-4
GO:2000352	negative regulation of endothelial cell apoptosis	2.213178e-4
GO:0000084	S phase of mitotic cell cycle	2.250859e-4
GO:0034333	adherens junction assembly	2.390815e-4
GO:0035441	cell migration involved in vasculogenesis	2.432381e-4
GO:0010107	potassium ion import	2.432381e-4
GO:0090399	replicative senescence	2.489588e-4
GO:0009956	radial pattern formation	2.501856e-4
GO:0060059	embryonic retina morphogenesis in camera-type eye	2.526854e-4
GO:0071542	dopaminergic neuron differentiation	2.526854e-4
GO:0043280	positive regulation of caspase activity	2.678394e-4
GO:0006790	sulfur compound metabolic process	2.691081e-4
GO:0061381	cell migration in diencephalon	2.761931e-4
GO:0061379	inferior colliculus development	2.761931e-4
GO:0061374	mammillothalamic axonal tract development	2.761931e-4
GO:0021855	hypothalamus cell migration	2.761931e-4
GO:0097105	presynaptic membrane assembly	2.831236e-4
GO:0006549	isoleucine metabolic process	2.980204e-4
GO:0030035	microspike assembly	2.989768e-4
GO:0042418	epinephrine biosynthetic process	3.102725e-4
GO:0006585	dopamine biosynthetic process from tyrosine	3.102725e-4
GO:0090278	negative regulation of peptide hormone secretion	3.165559e-4
GO:0070227	lymphocyte apoptosis	3.186630e-4
GO:0000255	allantoin metabolic process	3.245940e-4
GO:0060261	positive regulation of transcription initiation from RNA polymerase II promoter	3.283306e-4
GO:0007412	axon target recognition	3.283306e-4
GO:0048103	somatic stem cell division	3.359668e-4
GO:0034136	negative regulation of toll-like receptor 2 signaling pathway	3.488987e-4
GO:0046796	viral genome transport in host cell	3.578313e-4
GO:0003057	regulation of the force of heart contraction by chemical signal	3.604283e-4
GO:0031115	negative regulation of microtubule polymerization	3.787827e-4
GO:0050996	positive regulation of lipid catabolic process	3.837873e-4
GO:0046847	filopodium assembly	3.850941e-4
GO:0072195	kidney smooth muscle cell differentiation	3.866792e-4
GO:0072105	ureteric peristalsis	3.866792e-4
GO:0021997	neural plate axis specification	3.866792e-4
GO:0070858	negative regulation of bile acid biosynthetic process	3.866792e-4
GO:0003108	negative regulation of the force of heart contraction by chemical signal	4.041763e-4
GO:0051571	positive regulation of histone H3-K4 methylation	4.181299e-4
GO:0046888	negative regulation of hormone secretion	4.201739e-4
GO:0043648	dicarboxylic acid metabolic process	4.250079e-4
GO:0001660	fever generation	4.289340e-4
GO:0009081	branched chain family amino acid metabolic process	4.318587e-4
GO:0031397	negative regulation of protein ubiquitination	4.397268e-4
GO:0071951	conversion of methionyl-tRNA to N-formyl-methionyl-tRNA	4.470573e-4
GO:0021610	facial nerve morphogenesis	4.509074e-4
GO:0000414	regulation of histone H3-K36 methylation	4.509074e-4
GO:0046778	modification by virus of host mRNA processing	4.530338e-4
GO:0032365	intracellular lipid transport	4.609957e-4
GO:0032729	positive regulation of interferon-gamma production	4.705191e-4
GO:0042149	cellular response to glucose starvation	4.744299e-4
GO:0090224	regulation of spindle organization	4.880180e-4
GO:0030917	midbrain-hindbrain boundary development	4.986596e-4
GO:0051262	protein tetramerization	5.116124e-4
GO:2000348	regulation of CD40 signaling pathway	5.239217e-4
GO:0035066	positive regulation of histone acetylation	5.547686e-4
GO:0034140	negative regulation of toll-like receptor 3 signaling pathway	5.776824e-4
GO:0060558	regulation of calcidiol 1-monooxygenase activity	5.989868e-4
GO:0009059	macromolecule biosynthetic process	6.016674e-4
GO:0000724	double-strand break repair via homologous recombination	6.084048e-4
GO:0060690	epithelial cell differentiation involved in salivary gland development	6.110386e-4
GO:0071625	vocalization behavior	6.118367e-4
GO:0048541	Peyer's patch development	6.265740e-4
GO:0022403	cell cycle phase	6.359266e-4
GO:0061324	canonical Wnt receptor signaling pathway involved in positive regulation of cardiac outflow tract cell proliferation	6.381677e-4
GO:0043653	mitochondrial fragmentation involved in apoptosis	6.381677e-4
GO:0001985	negative regulation of heart rate involved in baroreceptor response to increased systemic arterial blood pressure	6.459587e-4
GO:0021873	forebrain neuroblast division	6.507084e-4
GO:0007127	meiosis I	6.541949e-4
GO:0035247	peptidyl-arginine omega-N-methylation	6.619996e-4
GO:0021561	facial nerve development	6.619996e-4
GO:0070428	regulation of nucleotide-binding oligomerization domain containing 1 signaling pathway	6.669561e-4
GO:0070432	regulation of nucleotide-binding oligomerization domain containing 2 signaling pathway	6.669561e-4
GO:0030497	fatty acid elongation	6.962946e-4
GO:0051043	regulation of membrane protein ectodomain proteolysis	6.977451e-4
GO:0000725	recombinational repair	6.977451e-4
GO:0031427	response to methotrexate	7.039697e-4
GO:0045769	negative regulation of asymmetric cell division	7.213511e-4
GO:0042414	epinephrine metabolic process	7.213511e-4
GO:0034144	negative regulation of toll-like receptor 4 signaling pathway	7.326670e-4
GO:0006695	cholesterol biosynthetic process	7.358973e-4
GO:0043137	DNA replication, removal of RNA primer	7.375561e-4
GO:0003360	brainstem development	7.375561e-4
GO:0034116	positive regulation of heterotypic cell-cell adhesion	7.606239e-4
GO:0002238	response to molecule of fungal origin	7.660309e-4
GO:0021943	formation of radial glial scaffolds	7.660309e-4
GO:0042770	signal transduction in response to DNA damage	7.829201e-4
GO:2000050	regulation of non-canonical Wnt receptor signaling pathway	7.900252e-4
GO:0021604	cranial nerve structural organization	7.974857e-4
GO:0006338	chromatin remodeling	8.122104e-4
GO:0000375	RNA splicing, via transesterification reactions	8.304895e-4
GO:0042113	B cell activation	8.423462e-4
GO:0071108	protein K48-linked deubiquitination	8.473323e-4
GO:0006551	leucine metabolic process	8.737008e-4
GO:0060968	regulation of gene silencing	8.836344e-4
GO:0045292	nuclear mRNA cis splicing, via spliceosome	9.496419e-4
GO:0008156	negative regulation of DNA replication	9.598066e-4
GO:0060292	long term synaptic depression	9.630883e-4
GO:0033601	positive regulation of mammary gland epithelial cell proliferation	9.914392e-4
GO:0071157	negative regulation of cell cycle arrest	1.008310e-3
GO:0006284	base-excision repair	1.010852e-3
GO:0090149	membrane fission involved in mitochondrial fission	1.014276e-3
GO:0003374	dynamin polymerization involved in mitochondrial fission	1.014276e-3
GO:0009088	threonine biosynthetic process	1.014276e-3
GO:0045830	positive regulation of isotype switching	1.042146e-3
GO:0034063	stress granule assembly	1.052140e-3
GO:0051131	chaperone-mediated protein complex assembly	1.072846e-3
GO:0002792	negative regulation of peptide secretion	1.075879e-3
GO:0015966	diadenosine tetraphosphate biosynthetic process	1.076692e-3
GO:0045076	regulation of interleukin-2 biosynthetic process	1.082959e-3
GO:0051402	neuron apoptosis	1.092309e-3
GO:0034135	regulation of toll-like receptor 2 signaling pathway	1.099166e-3
GO:0060173	limb development	1.119584e-3
GO:0070544	histone H3-K36 demethylation	1.125026e-3
GO:0002706	regulation of lymphocyte mediated immunity	1.125230e-3
GO:0001841	neural tube formation	1.146483e-3
GO:0006573	valine metabolic process	1.159068e-3
GO:0048537	mucosal-associated lymphoid tissue development	1.176037e-3
GO:0007213	muscarinic acetylcholine receptor signaling pathway	1.176127e-3
GO:0006366	transcription from RNA polymerase II promoter	1.194226e-3
GO:0034080	CenH3-containing nucleosome assembly at centromere	1.212836e-3
GO:0048469	cell maturation	1.215924e-3
GO:0071397	cellular response to cholesterol	1.222396e-3
GO:0070681	glutaminyl-tRNAGln biosynthesis via transamidation	1.244325e-3
GO:0010564	regulation of cell cycle process	1.265238e-3
GO:0016571	histone methylation	1.270277e-3
GO:0032770	positive regulation of monooxygenase activity	1.284490e-3
GO:0006982	response to lipid hydroperoxide	1.320907e-3
GO:0002158	osteoclast proliferation	1.334863e-3
GO:0046487	glyoxylate metabolic process	1.353317e-3
GO:0042214	terpene metabolic process	1.372695e-3
GO:0014813	satellite cell commitment	1.372695e-3
GO:0000038	very long-chain fatty acid metabolic process	1.380123e-3
GO:0044340	canonical Wnt receptor signaling pathway involved in regulation of cell proliferation	1.408570e-3
GO:0035137	hindlimb morphogenesis	1.453755e-3
GO:0001922	B-1 B cell homeostasis	1.479564e-3
GO:0032464	positive regulation of protein homooligomerization	1.483801e-3
GO:0014805	smooth muscle adaptation	1.541836e-3
GO:0008152	metabolic process	1.556862e-3
GO:0006974	response to DNA damage stimulus	1.609464e-3
GO:0071156	regulation of cell cycle arrest	1.616090e-3
GO:0051276	chromosome organization	1.625501e-3
GO:2000345	regulation of hepatocyte proliferation	1.672863e-3
GO:0002709	regulation of T cell mediated immunity	1.677112e-3
GO:0070857	regulation of bile acid biosynthetic process	1.677938e-3
GO:0090244	Wnt receptor signaling pathway involved in somitogenesis	1.681113e-3
GO:0035261	external genitalia morphogenesis	1.681113e-3
GO:0033129	positive regulation of histone phosphorylation	1.695500e-3
GO:0008630	DNA damage response, signal transduction resulting in induction of apoptosis	1.720286e-3
GO:0050796	regulation of insulin secretion	1.757013e-3
GO:0009067	aspartate family amino acid biosynthetic process	1.765179e-3
GO:0035425	autocrine signaling	1.770409e-3
GO:0032229	negative regulation of synaptic transmission, GABAergic	1.771308e-3
GO:0097090	presynaptic membrane organization	1.772473e-3
GO:0006283	transcription-coupled nucleotide-excision repair	1.787441e-3
GO:0043254	regulation of protein complex assembly	1.794362e-3
GO:0052314	phytoalexin metabolic process	1.801505e-3
GO:0033342	negative regulation of collagen binding	1.801505e-3
GO:0030264	nuclear fragmentation involved in apoptotic nuclear change	1.801505e-3
GO:0060977	coronary vasculature morphogenesis	1.831521e-3
GO:0048285	organelle fission	1.837130e-3
GO:0060559	positive regulation of calcidiol 1-monooxygenase activity	1.849856e-3
GO:0046619	optic placode formation involved in camera-type eye formation	1.871817e-3
GO:0051252	regulation of RNA metabolic process	1.939023e-3
GO:0002639	positive regulation of immunoglobulin production	1.995820e-3
GO:0060019	radial glial cell differentiation	2.004979e-3
GO:0007131	reciprocal meiotic recombination	2.006087e-3
GO:2000756	regulation of peptidyl-lysine acetylation	2.011452e-3
GO:0006825	copper ion transport	2.015462e-3
GO:0051726	regulation of cell cycle	2.048330e-3
GO:0046358	butyrate biosynthetic process	2.057489e-3
GO:2000114	regulation of establishment of cell polarity	2.075103e-3
GO:0021903	rostrocaudal neural tube patterning	2.079056e-3
GO:0002331	pre-B cell allelic exclusion	2.081577e-3
GO:0007128	meiotic prophase I	2.102669e-3
GO:0046850	regulation of bone remodeling	2.110735e-3
GO:0043414	macromolecule methylation	2.144860e-3
GO:0040032	post-embryonic body morphogenesis	2.162660e-3
GO:0000239	pachytene	2.162660e-3
GO:0006749	glutathione metabolic process	2.207896e-3
GO:0045911	positive regulation of DNA recombination	2.233971e-3
GO:0021932	hindbrain radial glia guided cell migration	2.284393e-3
GO:0007032	endosome organization	2.302181e-3
GO:0046690	response to tellurium ion	2.305204e-3
GO:0035444	nickel ion transmembrane transport	2.305204e-3
GO:0070627	ferrous iron import	2.305204e-3
GO:0071352	cellular response to interleukin-2	2.305204e-3
GO:0015676	vanadium ion transport	2.305204e-3
GO:0015692	lead ion transport	2.305204e-3
GO:0003257	positive regulation of transcription from RNA polymerase II promoter involved in myocardial precursor cell differentiation	2.305204e-3
GO:0009645	response to low light intensity stimulus	2.305204e-3
GO:0034755	iron ion transmembrane transport	2.307965e-3
GO:0015959	diadenosine polyphosphate metabolic process	2.307965e-3
GO:0031104	dendrite regeneration	2.375159e-3
GO:0060039	pericardium development	2.391845e-3
GO:0006308	DNA catabolic process	2.394482e-3
GO:2000276	negative regulation of oxidative phosphorylation uncoupler activity	2.551732e-3
GO:0035359	negative regulation of peroxisome proliferator activated receptor signaling pathway	2.551732e-3
GO:0019915	lipid storage	2.553677e-3
GO:0051301	cell division	2.555643e-3
GO:0030730	sequestering of triglyceride	2.585824e-3
GO:0080164	regulation of nitric oxide metabolic process	2.607351e-3
GO:0043381	negative regulation of memory T cell differentiation	2.607351e-3
GO:0030201	heparan sulfate proteoglycan metabolic process	2.645879e-3
GO:0050691	regulation of defense response to virus by host	2.645879e-3
GO:0021987	cerebral cortex development	2.663549e-3
GO:0032819	positive regulation of natural killer cell proliferation	2.705581e-3
GO:0001983	baroreceptor response to increased systemic arterial blood pressure	2.705581e-3
GO:0044339	canonical Wnt receptor signaling pathway involved in osteoblast differentiation	2.724987e-3
GO:0044338	canonical Wnt receptor signaling pathway involved in mesenchymal stem cell differentiation	2.724987e-3
GO:2001054	negative regulation of mesenchymal cell apoptosis	2.724987e-3
GO:0010587	miRNA catabolic process	2.724987e-3
GO:0009202	deoxyribonucleoside triphosphate biosynthetic process	2.724987e-3
GO:0021986	habenula development	2.741460e-3
GO:0033599	regulation of mammary gland epithelial cell proliferation	2.751158e-3
GO:0006105	succinate metabolic process	2.802557e-3
GO:0009450	gamma-aminobutyric acid catabolic process	2.813629e-3
GO:0032768	regulation of monooxygenase activity	2.837828e-3
GO:0032825	positive regulation of natural killer cell differentiation	2.858669e-3
GO:0006355	regulation of transcription, DNA-dependent	2.886463e-3
GO:0009822	alkaloid catabolic process	2.887906e-3
GO:0045799	positive regulation of chromatin assembly or disassembly	2.887906e-3
GO:0051661	maintenance of centrosome location	2.887906e-3
GO:0045472	response to ether	2.887906e-3
GO:0019218	regulation of steroid metabolic process	2.925136e-3
GO:0051891	positive regulation of cardioblast differentiation	2.942157e-3
GO:0090273	regulation of somatostatin secretion	3.018421e-3
GO:0001994	norepinephrine-epinephrine vasoconstriction involved in regulation of systemic arterial blood pressure	3.018421e-3
GO:0051204	protein insertion into mitochondrial membrane	3.052736e-3
GO:0031055	chromatin remodeling at centromere	3.056016e-3
GO:0022038	corpus callosum development	3.086390e-3
GO:0072194	kidney smooth muscle tissue development	3.094410e-3
GO:0050893	sensory processing	3.094410e-3
GO:0006426	glycyl-tRNA aminoacylation	3.108515e-3
GO:0006273	lagging strand elongation	3.108515e-3
GO:0010459	negative regulation of heart rate	3.122486e-3
GO:0045588	positive regulation of gamma-delta T cell differentiation	3.185030e-3
GO:0033865	nucleoside bisphosphate metabolic process	3.188243e-3
GO:0034103	regulation of tissue remodeling	3.190674e-3
GO:0032201	telomere maintenance via semi-conservative replication	3.199164e-3
GO:0032000	positive regulation of fatty acid beta-oxidation	3.264618e-3
GO:0051205	protein insertion into membrane	3.357219e-3
GO:0006309	DNA fragmentation involved in apoptotic nuclear change	3.372019e-3
GO:0034626	fatty acid elongation, polyunsaturated fatty acid	3.394826e-3
GO:0060689	cell differentiation involved in salivary gland development	3.394826e-3
GO:0045410	positive regulation of interleukin-6 biosynthetic process	3.408850e-3
GO:0072560	type B pancreatic cell maturation	3.429051e-3
GO:0070295	renal water absorption	3.429051e-3
GO:0030910	olfactory placode formation	3.429051e-3
GO:0032645	regulation of granulocyte macrophage colony-stimulating factor production	3.488059e-3
GO:0014048	regulation of glutamate secretion	3.510248e-3
GO:2000116	regulation of cysteine-type endopeptidase activity	3.517889e-3
GO:0001838	embryonic epithelial tube formation	3.520434e-3
GO:0060061	Spemann organizer formation	3.527260e-3
GO:0033076	isoquinoline alkaloid metabolic process	3.553358e-3
GO:0006325	chromatin organization	3.684319e-3
GO:0021912	regulation of transcription from RNA polymerase II promoter involved in spinal cord motor neuron fate specification	3.684455e-3
GO:0015891	siderophore transport	3.715629e-3
GO:0042339	keratan sulfate metabolic process	3.715629e-3
GO:0006463	steroid hormone receptor complex assembly	3.715629e-3
GO:0035246	peptidyl-arginine N-methylation	3.727964e-3
GO:0032817	regulation of natural killer cell proliferation	3.727964e-3
GO:0045822	negative regulation of heart contraction	3.841926e-3
GO:0006927	transformed cell apoptosis	3.890100e-3
GO:0055024	regulation of cardiac muscle tissue development	3.890634e-3
GO:0045647	negative regulation of erythrocyte differentiation	3.923976e-3
GO:0060973	cell migration involved in heart development	3.953696e-3
GO:0006600	creatine metabolic process	4.175992e-3
GO:0048593	camera-type eye morphogenesis	4.228508e-3
GO:0008535	respiratory chain complex IV assembly	4.237216e-3
GO:0031424	keratinization	4.282531e-3
GO:2000270	negative regulation of fibroblast apoptosis	4.304962e-3
GO:2000271	positive regulation of fibroblast apoptosis	4.304962e-3
GO:2000080	negative regulation of canonical Wnt receptor signaling pathway involved in controlling type B pancreatic cell proliferation	4.304962e-3
GO:0071773	cellular response to BMP stimulus	4.304962e-3
GO:0044345	stromal-epithelial cell signaling involved in prostate gland development	4.304962e-3
GO:0017145	stem cell division	4.335620e-3
GO:2000677	regulation of transcription regulatory region DNA binding	4.364463e-3
GO:0043044	ATP-dependent chromatin remodeling	4.364463e-3
GO:0051790	short-chain fatty acid biosynthetic process	4.476285e-3
GO:0070105	positive regulation of interleukin-6-mediated signaling pathway	4.476285e-3
GO:2000820	negative regulation of transcription from RNA polymerase II promoter involved in smooth muscle cell differentiation	4.476285e-3
GO:0032066	nucleolus to nucleoplasm transport	4.476285e-3
GO:0010248	establishment or maintenance of transmembrane electrochemical gradient	4.476285e-3
GO:0006533	aspartate catabolic process	4.476285e-3
GO:0000018	regulation of DNA recombination	4.497689e-3
GO:0060535	trachea cartilage morphogenesis	4.535459e-3
GO:0018216	peptidyl-arginine methylation	4.559945e-3
GO:0046851	negative regulation of bone remodeling	4.633782e-3
GO:0031396	regulation of protein ubiquitination	4.649189e-3
GO:0043486	histone exchange	4.756443e-3
GO:0051324	prophase	4.761681e-3
GO:0043517	positive regulation of DNA damage response, signal transduction by p53 class mediator	4.788598e-3
GO:0006528	asparagine metabolic process	4.807838e-3
GO:0006334	nucleosome assembly	4.827721e-3
GO:0070672	response to interleukin-15	4.848868e-3
GO:0032057	negative regulation of translational initiation in response to stress	5.009422e-3
GO:0046645	positive regulation of gamma-delta T cell activation	5.025930e-3
GO:0008299	isoprenoid biosynthetic process	5.068569e-3
GO:0035148	tube formation	5.119134e-3
GO:0072175	epithelial tube formation	5.126164e-3
GO:2000079	regulation of canonical Wnt receptor signaling pathway involved in controlling type B pancreatic cell proliferation	5.145786e-3
GO:0051097	negative regulation of helicase activity	5.145786e-3
GO:0034139	regulation of toll-like receptor 3 signaling pathway	5.167818e-3
GO:0046185	aldehyde catabolic process	5.217644e-3
GO:0032259	methylation	5.239051e-3
GO:2000112	regulation of cellular macromolecule biosynthetic process	5.246462e-3
GO:0060976	coronary vasculature development	5.289211e-3
GO:0035634	response to stilbenoid	5.289211e-3
GO:0000266	mitochondrial fission	5.289211e-3
GO:0022616	DNA strand elongation	5.298073e-3
GO:0021700	developmental maturation	5.300888e-3
GO:0001782	B cell homeostasis	5.391958e-3
GO:0006607	NLS-bearing substrate import into nucleus	5.410055e-3
GO:0042416	dopamine biosynthetic process	5.422615e-3
GO:0034392	negative regulation of smooth muscle cell apoptosis	5.458560e-3
GO:0009068	aspartate family amino acid catabolic process	5.485203e-3
GO:0051569	regulation of histone H3-K4 methylation	5.485203e-3
GO:0000083	regulation of transcription involved in G1/S phase of mitotic cell cycle	5.554638e-3
GO:0001743	optic placode formation	5.651540e-3
GO:0014050	negative regulation of glutamate secretion	5.694294e-3
GO:0050891	multicellular organismal water homeostasis	5.703402e-3
GO:0001659	temperature homeostasis	5.743359e-3
GO:0051436	negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle	5.754486e-3
GO:0006646	phosphatidylethanolamine biosynthetic process	5.760175e-3
GO:0032876	negative regulation of DNA endoreduplication	5.760175e-3
GO:0010952	positive regulation of peptidase activity	5.852090e-3
GO:0061316	canonical Wnt receptor signaling pathway involved in heart development	5.884541e-3
GO:0051353	positive regulation of oxidoreductase activity	5.938254e-3
GO:0000398	nuclear mRNA splicing, via spliceosome	5.975443e-3
GO:0090276	regulation of peptide hormone secretion	6.027211e-3
GO:0016140	O-glycoside metabolic process	6.078583e-3
GO:0035024	negative regulation of Rho protein signal transduction	6.109727e-3
GO:0000019	regulation of mitotic recombination	6.110247e-3
GO:0071168	protein localization to chromatin	6.110247e-3
GO:0010948	negative regulation of cell cycle process	6.147205e-3
GO:0051930	regulation of sensory perception of pain	6.194275e-3
GO:0001779	natural killer cell differentiation	6.292686e-3

GREAT analysis results for mouseGenomic Enrichment of Annotations Tool (GREAT, Nat Biotechnol. 2010 May;28(5):495-501) is used to identify, both in human and in mouse, the gene ontology terms of biological processes enriched given the predicted TFBSs, and evaluated the overlap in the top-500 gene ontology terms between human and mouse. For each novel motif, the P value for the overlap was then evaluated by calculating its relative rank with respect to this background distribution.<br>Analyst: Michiel de Hoon <br><br>link to source dataset <br>data

---

GO ID	GO Term	p-value
GO:0090304	nucleic acid metabolic process	1.994331e-16
GO:0016070	RNA metabolic process	2.861030e-12
GO:0006139	nucleobase-containing compound metabolic process	7.413870e-12
GO:0044260	cellular macromolecule metabolic process	1.533992e-11
GO:0042733	embryonic digit morphogenesis	1.627549e-11
GO:0010467	gene expression	1.023694e-10
GO:0034641	cellular nitrogen compound metabolic process	3.504483e-10
GO:0006807	nitrogen compound metabolic process	8.893119e-10
GO:0003309	type B pancreatic cell differentiation	9.441651e-10
GO:0060429	epithelium development	9.780988e-10
GO:0001736	establishment of planar polarity	1.119363e-9
GO:0045736	negative regulation of cyclin-dependent protein kinase activity	1.316519e-9
GO:0001945	lymph vessel development	1.536995e-9
GO:0007164	establishment of tissue polarity	2.716312e-9
GO:0051684	maintenance of Golgi location	3.641314e-9
GO:0046709	IDP catabolic process	4.431151e-9
GO:0046032	ADP catabolic process	4.431151e-9
GO:0051726	regulation of cell cycle	5.683420e-9
GO:0003279	cardiac septum development	6.238593e-9
GO:0043170	macromolecule metabolic process	6.338225e-9
GO:0060411	cardiac septum morphogenesis	1.093255e-8
GO:0051645	Golgi localization	2.699758e-8
GO:0045786	negative regulation of cell cycle	4.790769e-8
GO:0030855	epithelial cell differentiation	7.301743e-8
GO:0006974	response to DNA damage stimulus	8.774461e-8
GO:0009956	radial pattern formation	9.461499e-8
GO:0032774	RNA biosynthetic process	9.925289e-8
GO:0015074	DNA integration	1.054522e-7
GO:0001738	morphogenesis of a polarized epithelium	1.369369e-7
GO:0035282	segmentation	1.371055e-7
GO:0032912	negative regulation of transforming growth factor beta2 production	1.551173e-7
GO:0031577	spindle checkpoint	1.640761e-7
GO:0051301	cell division	2.636669e-7
GO:0006351	transcription, DNA-dependent	2.686968e-7
GO:0007067	mitosis	2.914650e-7
GO:0060849	regulation of transcription involved in lymphatic endothelial cell fate commitment	2.969826e-7
GO:0007389	pattern specification process	3.556897e-7
GO:0009952	anterior/posterior pattern specification	3.599216e-7
GO:0031503	protein complex localization	3.777013e-7
GO:0060839	endothelial cell fate commitment	3.937405e-7
GO:0051661	maintenance of centrosome location	4.282727e-7
GO:0060836	lymphatic endothelial cell differentiation	4.518201e-7
GO:0000087	M phase of mitotic cell cycle	4.696605e-7
GO:0090179	planar cell polarity pathway involved in neural tube closure	5.910800e-7
GO:0045165	cell fate commitment	5.955319e-7
GO:0071156	regulation of cell cycle arrest	6.266562e-7
GO:0045137	development of primary sexual characteristics	6.673101e-7
GO:0046452	dihydrofolate metabolic process	8.732728e-7
GO:0072240	metanephric DCT cell differentiation	9.468874e-7
GO:0072227	metanephric macula densa development	9.468874e-7
GO:0043066	negative regulation of apoptosis	1.147592e-6
GO:0031427	response to methotrexate	1.240022e-6
GO:0043069	negative regulation of programmed cell death	1.305778e-6
GO:0048286	lung alveolus development	1.375355e-6
GO:0006281	DNA repair	1.416157e-6
GO:0009181	purine ribonucleoside diphosphate catabolic process	1.482575e-6
GO:0060412	ventricular septum morphogenesis	1.603707e-6
GO:0006420	arginyl-tRNA aminoacylation	1.609321e-6
GO:0061180	mammary gland epithelium development	1.774581e-6
GO:0034645	cellular macromolecule biosynthetic process	2.017681e-6
GO:0007493	endodermal cell fate determination	2.035677e-6
GO:0007548	sex differentiation	2.047806e-6
GO:0048285	organelle fission	2.231136e-6
GO:0003002	regionalization	2.279784e-6
GO:0046661	male sex differentiation	2.523897e-6
GO:0009059	macromolecule biosynthetic process	2.679225e-6
GO:0034063	stress granule assembly	2.853042e-6
GO:0003281	ventricular septum development	3.020813e-6
GO:0045995	regulation of embryonic development	3.063880e-6
GO:0072233	metanephric thick ascending limb development	3.280594e-6
GO:0072218	metanephric ascending thin limb development	3.280594e-6
GO:0060548	negative regulation of cell death	3.404785e-6
GO:0042475	odontogenesis of dentine-containing tooth	3.604803e-6
GO:0071542	dopaminergic neuron differentiation	3.652544e-6
GO:0003151	outflow tract morphogenesis	4.207354e-6
GO:0060071	Wnt receptor signaling pathway, planar cell polarity pathway	4.394822e-6
GO:0008406	gonad development	4.474877e-6
GO:0071173	spindle assembly checkpoint	5.590752e-6
GO:0000279	M phase	5.658895e-6
GO:0072202	cell differentiation involved in metanephros development	5.855346e-6
GO:0032908	regulation of transforming growth factor beta1 production	5.855346e-6
GO:0009236	cobalamin biosynthetic process	5.914190e-6
GO:0032911	negative regulation of transforming growth factor beta1 production	6.387055e-6
GO:0072148	epithelial cell fate commitment	6.465315e-6
GO:0060173	limb development	6.780211e-6
GO:0046031	ADP metabolic process	7.278483e-6
GO:0060644	mammary gland epithelial cell differentiation	7.289085e-6
GO:0021889	olfactory bulb interneuron differentiation	8.162105e-6
GO:0030801	positive regulation of cyclic nucleotide metabolic process	8.846900e-6
GO:0034622	cellular macromolecular complex assembly	9.095485e-6
GO:0034421	post-translational protein acetylation	9.207778e-6
GO:0007566	embryo implantation	9.484220e-6
GO:0035050	embryonic heart tube development	9.630088e-6
GO:0035567	non-canonical Wnt receptor signaling pathway	1.020374e-5
GO:0007420	brain development	1.152230e-5
GO:0030326	embryonic limb morphogenesis	1.161836e-5
GO:0035967	cellular response to topologically incorrect protein	1.195433e-5
GO:0021869	forebrain ventricular zone progenitor cell division	1.368730e-5
GO:0016073	snRNA metabolic process	1.382551e-5
GO:0050678	regulation of epithelial cell proliferation	1.532934e-5
GO:0071158	positive regulation of cell cycle arrest	1.615548e-5
GO:0000578	embryonic axis specification	1.627559e-5
GO:0006259	DNA metabolic process	1.634823e-5
GO:0022403	cell cycle phase	1.654395e-5
GO:0060371	regulation of atrial cardiomyocyte membrane depolarization	1.704086e-5
GO:0060599	lateral sprouting involved in mammary gland duct morphogenesis	1.864742e-5
GO:0061381	cell migration in diencephalon	2.059990e-5
GO:0061379	inferior colliculus development	2.059990e-5
GO:0010045	response to nickel ion	2.059990e-5
GO:0021855	hypothalamus cell migration	2.059990e-5
GO:0061374	mammillothalamic axonal tract development	2.059990e-5
GO:0006355	regulation of transcription, DNA-dependent	2.132386e-5
GO:0008625	induction of apoptosis via death domain receptors	2.379919e-5
GO:0051085	chaperone mediated protein folding requiring cofactor	2.478191e-5
GO:0051382	kinetochore assembly	2.495486e-5
GO:0045345	positive regulation of MHC class I biosynthetic process	2.495486e-5
GO:0022402	cell cycle process	2.540236e-5
GO:0050680	negative regulation of epithelial cell proliferation	2.543774e-5
GO:0060575	intestinal epithelial cell differentiation	2.635289e-5
GO:0002009	morphogenesis of an epithelium	2.686537e-5
GO:0003310	pancreatic A cell differentiation	2.979496e-5
GO:0009889	regulation of biosynthetic process	3.039701e-5
GO:0051252	regulation of RNA metabolic process	3.058783e-5
GO:0070389	chaperone cofactor-dependent protein refolding	3.101941e-5
GO:0007223	Wnt receptor signaling pathway, calcium modulating pathway	3.180781e-5
GO:0022011	myelination in peripheral nervous system	3.180781e-5
GO:0034621	cellular macromolecular complex subunit organization	3.244006e-5
GO:0046092	deoxycytidine metabolic process	3.329255e-5
GO:0090094	metanephric cap mesenchymal cell proliferation involved in metanephros development	3.377188e-5
GO:2000065	negative regulation of cortisol biosynthetic process	3.377188e-5
GO:0072259	metanephric interstitial cell development	3.377188e-5
GO:0072208	metanephric smooth muscle tissue development	3.377188e-5
GO:0032348	negative regulation of aldosterone biosynthetic process	3.377188e-5
GO:0072169	specification of posterior mesonephric tubule identity	3.377188e-5
GO:0072168	specification of anterior mesonephric tubule identity	3.377188e-5
GO:0072184	renal vesicle progenitor cell differentiation	3.377188e-5
GO:0045541	negative regulation of cholesterol biosynthetic process	3.535994e-5
GO:0060931	sinoatrial node cell development	4.059727e-5
GO:0003167	atrioventricular bundle cell differentiation	4.059727e-5
GO:0042476	odontogenesis	4.168463e-5
GO:0009191	ribonucleoside diphosphate catabolic process	4.428682e-5
GO:0060795	cell fate commitment involved in formation of primary germ layers	4.451088e-5
GO:0007049	cell cycle	4.479864e-5
GO:0071712	ER-associated misfolded protein catabolic process	5.630273e-5
GO:0030970	retrograde protein transport, ER to cytosol	5.630273e-5
GO:0048608	reproductive structure development	5.649002e-5
GO:0019219	regulation of nucleobase-containing compound metabolic process	5.857137e-5
GO:0071635	negative regulation of transforming growth factor beta production	5.915221e-5
GO:0090399	replicative senescence	6.495716e-5
GO:0009134	nucleoside diphosphate catabolic process	6.495716e-5
GO:0007094	mitotic cell cycle spindle assembly checkpoint	7.053621e-5
GO:0051383	kinetochore organization	7.162774e-5
GO:0045446	endothelial cell differentiation	7.167759e-5
GO:0001756	somitogenesis	7.273054e-5
GO:2000112	regulation of cellular macromolecule biosynthetic process	7.591432e-5
GO:0060638	mesenchymal-epithelial cell signaling	7.598545e-5
GO:0010556	regulation of macromolecule biosynthetic process	7.816859e-5
GO:0071174	mitotic cell cycle spindle checkpoint	8.031172e-5
GO:0007569	cell aging	8.095122e-5
GO:0035136	forelimb morphogenesis	8.359744e-5
GO:2000617	positive regulation of histone H3-K9 acetylation	8.391304e-5
GO:2000620	positive regulation of histone H4-K16 acetylation	8.391304e-5
GO:0070512	positive regulation of histone H4-K20 methylation	8.391304e-5
GO:0061350	planar cell polarity pathway involved in cardiac muscle tissue morphogenesis	8.569089e-5
GO:0061354	planar cell polarity pathway involved in pericardium morphogenesis	8.569089e-5
GO:0061349	planar cell polarity pathway involved in cardiac right atrium morphogenesis	8.569089e-5
GO:0070314	G1 to G0 transition	8.569089e-5
GO:0060210	metestrus	8.569089e-5
GO:0061348	planar cell polarity pathway involved in ventricular septum morphogenesis	8.569089e-5
GO:0006651	diacylglycerol biosynthetic process	8.569089e-5
GO:0061347	planar cell polarity pathway involved in outflow tract morphogenesis	8.569089e-5
GO:0000278	mitotic cell cycle	8.826370e-5
GO:0035115	embryonic forelimb morphogenesis	8.961571e-5
GO:0048343	paraxial mesodermal cell fate commitment	8.997431e-5
GO:0061077	chaperone-mediated protein folding	9.115944e-5
GO:0060921	sinoatrial node cell differentiation	9.116364e-5
GO:2001022	positive regulation of response to DNA damage stimulus	9.267129e-5
GO:0042473	outer ear morphogenesis	9.320439e-5
GO:2000543	positive regulation of gastrulation	9.549174e-5
GO:0014044	Schwann cell development	9.598481e-5
GO:0002065	columnar/cuboidal epithelial cell differentiation	1.004685e-4
GO:2000049	positive regulation of cell-cell adhesion mediated by cadherin	1.005007e-4
GO:0009179	purine ribonucleoside diphosphate metabolic process	1.016843e-4
GO:0044249	cellular biosynthetic process	1.030187e-4
GO:0060982	coronary artery morphogenesis	1.031797e-4
GO:0021904	dorsal/ventral neural tube patterning	1.120958e-4
GO:0060932	His-Purkinje system cell differentiation	1.164520e-4
GO:0060926	pacemaker cell development	1.164520e-4
GO:0014034	neural crest cell fate commitment	1.172735e-4
GO:0044237	cellular metabolic process	1.186037e-4
GO:0061053	somite development	1.262741e-4
GO:0001895	retina homeostasis	1.310775e-4
GO:0065004	protein-DNA complex assembly	1.315502e-4
GO:0007422	peripheral nervous system development	1.331682e-4
GO:0002070	epithelial cell maturation	1.338004e-4
GO:0060067	cervix development	1.361918e-4
GO:0022618	ribonucleoprotein complex assembly	1.370970e-4
GO:0006975	DNA damage induced protein phosphorylation	1.372972e-4
GO:0021891	olfactory bulb interneuron development	1.403313e-4
GO:0003158	endothelium development	1.406217e-4
GO:0010463	mesenchymal cell proliferation	1.427157e-4
GO:0051171	regulation of nitrogen compound metabolic process	1.430734e-4
GO:0046884	follicle-stimulating hormone secretion	1.471575e-4
GO:0032275	luteinizing hormone secretion	1.471575e-4
GO:0008595	anterior/posterior axis specification, embryo	1.480112e-4
GO:0006261	DNA-dependent DNA replication	1.504375e-4
GO:0045343	regulation of MHC class I biosynthetic process	1.671128e-4
GO:0006396	RNA processing	1.715039e-4
GO:0031326	regulation of cellular biosynthetic process	1.724740e-4
GO:0072234	metanephric nephron tubule development	1.732580e-4
GO:0014037	Schwann cell differentiation	1.732580e-4
GO:0006457	protein folding	1.764629e-4
GO:0002741	positive regulation of cytokine secretion involved in immune response	1.812417e-4
GO:0072170	metanephric tubule development	1.824564e-4
GO:0090103	cochlea morphogenesis	1.835420e-4
GO:0007417	central nervous system development	1.934505e-4
GO:0001711	endodermal cell fate commitment	1.952478e-4
GO:0009058	biosynthetic process	1.981947e-4
GO:0000079	regulation of cyclin-dependent protein kinase activity	1.991227e-4
GO:0046952	ketone body catabolic process	2.021861e-4
GO:0003163	sinoatrial node development	2.052088e-4
GO:0072221	metanephric distal convoluted tubule development	2.052088e-4
GO:0045986	negative regulation of smooth muscle contraction	2.107107e-4
GO:0072207	metanephric epithelium development	2.126078e-4
GO:0003205	cardiac chamber development	2.174542e-4
GO:0060920	pacemaker cell differentiation	2.282150e-4
GO:0060743	epithelial cell maturation involved in prostate gland development	2.372984e-4
GO:0000083	regulation of transcription involved in G1/S phase of mitotic cell cycle	2.372984e-4
GO:0090009	primitive streak formation	2.408095e-4
GO:0051084	'de novo' posttranslational protein folding	2.408095e-4
GO:0060479	lung cell differentiation	2.411975e-4
GO:0010468	regulation of gene expression	2.495753e-4
GO:0001975	response to amphetamine	2.501048e-4
GO:0071826	ribonucleoprotein complex subunit organization	2.502823e-4
GO:0016071	mRNA metabolic process	2.526023e-4
GO:0045668	negative regulation of osteoblast differentiation	2.536302e-4
GO:0072017	distal tubule development	2.571593e-4
GO:0031576	G2/M transition checkpoint	2.597260e-4
GO:0060117	auditory receptor cell development	2.633010e-4
GO:0010470	regulation of gastrulation	2.648459e-4
GO:0042351	'de novo' GDP-L-fucose biosynthetic process	2.651930e-4
GO:0030799	regulation of cyclic nucleotide metabolic process	2.654800e-4
GO:0002011	morphogenesis of an epithelial sheet	2.661756e-4
GO:0051095	regulation of helicase activity	2.700103e-4
GO:0032287	peripheral nervous system myelin maintenance	2.700103e-4
GO:0017148	negative regulation of translation	2.784915e-4
GO:0003323	type B pancreatic cell development	2.804546e-4
GO:0042770	signal transduction in response to DNA damage	2.824523e-4
GO:2000798	negative regulation of amniotic stem cell differentiation	2.847505e-4
GO:2000706	negative regulation of dense core granule biogenesis	2.847505e-4
GO:0019047	provirus integration	2.847505e-4
GO:0046591	embryonic leg joint morphogenesis	2.866637e-4
GO:0030510	regulation of BMP signaling pathway	2.949183e-4
GO:0035987	endodermal cell differentiation	2.974067e-4
GO:0048850	hypophysis morphogenesis	3.061595e-4
GO:0033108	mitochondrial respiratory chain complex assembly	3.063845e-4
GO:0072236	metanephric loop of Henle development	3.099530e-4
GO:0044238	primary metabolic process	3.122245e-4
GO:0072091	regulation of stem cell proliferation	3.132766e-4
GO:0048339	paraxial mesoderm development	3.146563e-4
GO:0009890	negative regulation of biosynthetic process	3.190028e-4
GO:0061338	atrioventricular node impulse conduction delay	3.290589e-4
GO:0010558	negative regulation of macromolecule biosynthetic process	3.299038e-4
GO:0046546	development of primary male sexual characteristics	3.373015e-4
GO:0030879	mammary gland development	3.380856e-4
GO:0060285	ciliary cell motility	3.381922e-4
GO:0072194	kidney smooth muscle tissue development	3.381922e-4
GO:0043517	positive regulation of DNA damage response, signal transduction by p53 class mediator	3.381922e-4
GO:0060286	flagellar cell motility	3.411495e-4
GO:0030264	nuclear fragmentation involved in apoptotic nuclear change	3.411495e-4
GO:0042026	protein refolding	3.425099e-4
GO:0035108	limb morphogenesis	3.428238e-4
GO:0006463	steroid hormone receptor complex assembly	3.459938e-4
GO:0000075	cell cycle checkpoint	3.461672e-4
GO:0035117	embryonic arm morphogenesis	3.531006e-4
GO:0060039	pericardium development	3.550898e-4
GO:0007059	chromosome segregation	3.813137e-4
GO:0060850	regulation of transcription involved in cell fate commitment	3.913680e-4
GO:0046544	development of secondary male sexual characteristics	3.964291e-4
GO:0045081	negative regulation of interleukin-10 biosynthetic process	3.964291e-4
GO:0051276	chromosome organization	3.973485e-4
GO:0043029	T cell homeostasis	3.978735e-4
GO:0002066	columnar/cuboidal epithelial cell development	4.021273e-4
GO:0022613	ribonucleoprotein complex biogenesis	4.081170e-4
GO:0090398	cellular senescence	4.127112e-4
GO:0010894	negative regulation of steroid biosynthetic process	4.133404e-4
GO:0010159	specification of organ position	4.136531e-4
GO:0021837	motogenic signaling involved in postnatal olfactory bulb interneuron migration	4.314909e-4
GO:0072183	negative regulation of nephron tubule epithelial cell differentiation	4.314909e-4
GO:0060487	lung epithelial cell differentiation	4.476785e-4
GO:0031120	snRNA pseudouridine synthesis	4.486199e-4
GO:0060119	inner ear receptor cell development	4.490792e-4
GO:0048806	genitalia development	4.541221e-4
GO:0035425	autocrine signaling	4.619229e-4
GO:0042698	ovulation cycle	4.668701e-4
GO:0060021	palate development	4.707627e-4
GO:2000113	negative regulation of cellular macromolecule biosynthetic process	4.755040e-4
GO:0040019	positive regulation of embryonic development	4.766975e-4
GO:0061325	cell proliferation involved in outflow tract morphogenesis	4.902185e-4
GO:0003253	cardiac neural crest cell migration involved in outflow tract morphogenesis	4.902185e-4
GO:0032274	gonadotropin secretion	5.118502e-4
GO:0071824	protein-DNA complex subunit organization	5.146311e-4
GO:0071218	cellular response to misfolded protein	5.352383e-4
GO:0010501	RNA secondary structure unwinding	5.376771e-4
GO:0010564	regulation of cell cycle process	5.648631e-4
GO:0072070	loop of Henle development	5.691498e-4
GO:0001947	heart looping	5.702257e-4
GO:0033554	cellular response to stress	5.819707e-4
GO:0035966	response to topologically incorrect protein	5.831476e-4
GO:0003306	Wnt receptor signaling pathway involved in heart development	5.931107e-4
GO:0051890	regulation of cardioblast differentiation	5.979783e-4
GO:0060976	coronary vasculature development	6.010684e-4
GO:0003344	pericardium morphogenesis	6.097327e-4
GO:2000484	positive regulation of interleukin-8 secretion	6.097327e-4
GO:0044339	canonical Wnt receptor signaling pathway involved in osteoblast differentiation	6.169556e-4
GO:0046125	pyrimidine deoxyribonucleoside metabolic process	6.169556e-4
GO:0044338	canonical Wnt receptor signaling pathway involved in mesenchymal stem cell differentiation	6.169556e-4
GO:0002331	pre-B cell allelic exclusion	6.169556e-4
GO:0033599	regulation of mammary gland epithelial cell proliferation	6.292400e-4
GO:2000064	regulation of cortisol biosynthetic process	6.611871e-4
GO:0042350	GDP-L-fucose biosynthetic process	6.611871e-4
GO:0006545	glycine biosynthetic process	6.611871e-4
GO:0090239	regulation of histone H4 acetylation	6.626299e-4
GO:0014057	positive regulation of acetylcholine secretion	6.626299e-4
GO:0060340	positive regulation of type I interferon-mediated signaling pathway	6.773722e-4
GO:0003206	cardiac chamber morphogenesis	6.889755e-4
GO:0045841	negative regulation of mitotic metaphase/anaphase transition	7.034619e-4
GO:0021800	cerebral cortex tangential migration	7.034619e-4
GO:0042249	establishment of planar polarity of embryonic epithelium	7.076696e-4
GO:0009185	ribonucleoside diphosphate metabolic process	7.270495e-4
GO:0048469	cell maturation	7.439429e-4
GO:0014029	neural crest formation	7.506733e-4
GO:0030819	positive regulation of cAMP biosynthetic process	7.604583e-4
GO:0001936	regulation of endothelial cell proliferation	7.981886e-4
GO:0061337	cardiac conduction	8.211174e-4
GO:0060923	cardiac muscle cell fate commitment	8.294586e-4
GO:0009067	aspartate family amino acid biosynthetic process	8.836549e-4
GO:0008629	induction of apoptosis by intracellular signals	8.929176e-4
GO:0008354	germ cell migration	9.023365e-4
GO:0090037	positive regulation of protein kinase C signaling cascade	9.155274e-4
GO:0048539	bone marrow development	9.185338e-4
GO:0034720	histone H3-K4 demethylation	9.185338e-4
GO:2000369	regulation of clathrin-mediated endocytosis	9.321405e-4
GO:0031327	negative regulation of cellular biosynthetic process	9.371556e-4
GO:0003156	regulation of organ formation	9.575527e-4
GO:0046543	development of secondary female sexual characteristics	9.768464e-4
GO:0060430	lung saccule development	9.805614e-4
GO:0051881	regulation of mitochondrial membrane potential	9.805614e-4
GO:0003148	outflow tract septum morphogenesis	9.812870e-4
GO:0035404	histone-serine phosphorylation	1.007732e-3
GO:0007399	nervous system development	1.015339e-3
GO:0040008	regulation of growth	1.033803e-3
GO:0001539	ciliary or flagellar motility	1.096680e-3
GO:0032909	regulation of transforming growth factor beta2 production	1.100147e-3
GO:0030514	negative regulation of BMP signaling pathway	1.110748e-3
GO:0006309	DNA fragmentation involved in apoptotic nuclear change	1.123050e-3
GO:0030968	endoplasmic reticulum unfolded protein response	1.144804e-3
GO:0021986	habenula development	1.150613e-3
GO:0072133	metanephric mesenchyme morphogenesis	1.150613e-3
GO:0030804	positive regulation of cyclic nucleotide biosynthetic process	1.224797e-3
GO:0010765	positive regulation of sodium ion transport	1.246877e-3
GO:2000615	regulation of histone H3-K9 acetylation	1.262117e-3
GO:0060574	intestinal epithelial cell maturation	1.262117e-3
GO:0060315	negative regulation of ryanodine-sensitive calcium-release channel activity	1.262117e-3
GO:0033566	gamma-tubulin complex localization	1.262117e-3
GO:0071843	cellular component biogenesis at cellular level	1.276743e-3
GO:0016180	snRNA processing	1.316812e-3
GO:0051096	positive regulation of helicase activity	1.317897e-3
GO:0016556	mRNA modification	1.317897e-3
GO:2000679	positive regulation of transcription regulatory region DNA binding	1.327876e-3
GO:0021915	neural tube development	1.350575e-3
GO:2000242	negative regulation of reproductive process	1.354148e-3
GO:0060236	regulation of mitotic spindle organization	1.358390e-3
GO:0009235	cobalamin metabolic process	1.358390e-3
GO:0006529	asparagine biosynthetic process	1.358390e-3
GO:0055117	regulation of cardiac muscle contraction	1.389491e-3
GO:0030857	negative regulation of epithelial cell differentiation	1.439323e-3
GO:0007050	cell cycle arrest	1.442565e-3
GO:0051891	positive regulation of cardioblast differentiation	1.451267e-3
GO:0002262	myeloid cell homeostasis	1.464157e-3
GO:0051402	neuron apoptosis	1.513623e-3
GO:0060068	vagina development	1.531246e-3
GO:0045136	development of secondary sexual characteristics	1.538134e-3
GO:0021827	postnatal olfactory bulb interneuron migration	1.580168e-3
GO:0046654	tetrahydrofolate biosynthetic process	1.590979e-3
GO:0090072	positive regulation of sodium ion transport via voltage-gated sodium channel activity	1.590979e-3
GO:0035584	calcium-mediated signaling using intracellular calcium source	1.590979e-3
GO:0048843	negative regulation of axon extension involved in axon guidance	1.596218e-3
GO:0042491	auditory receptor cell differentiation	1.605587e-3
GO:0060947	cardiac vascular smooth muscle cell differentiation	1.610946e-3
GO:0001843	neural tube closure	1.625359e-3
GO:0009755	hormone-mediated signaling pathway	1.626222e-3
GO:0046620	regulation of organ growth	1.641385e-3
GO:0071681	cellular response to indole-3-methanol	1.647114e-3
GO:0043482	cellular pigment accumulation	1.647114e-3
GO:0045739	positive regulation of DNA repair	1.664965e-3
GO:0060788	ectodermal placode formation	1.667832e-3
GO:0060444	branching involved in mammary gland duct morphogenesis	1.671244e-3
GO:0071425	hemopoietic stem cell proliferation	1.694614e-3
GO:0060486	Clara cell differentiation	1.701808e-3
GO:0030823	regulation of cGMP metabolic process	1.701808e-3
GO:0003006	developmental process involved in reproduction	1.750920e-3
GO:0060986	endocrine hormone secretion	1.800270e-3
GO:0010870	positive regulation of receptor biosynthetic process	1.832616e-3
GO:0006515	misfolded or incompletely synthesized protein catabolic process	1.832616e-3
GO:0003231	cardiac ventricle development	1.837103e-3
GO:0055021	regulation of cardiac muscle tissue growth	1.858468e-3
GO:0060686	negative regulation of prostatic bud formation	1.867789e-3
GO:0042471	ear morphogenesis	1.867824e-3
GO:0006998	nuclear envelope organization	1.887250e-3
GO:0045647	negative regulation of erythrocyte differentiation	1.905753e-3
GO:0070979	protein K11-linked ubiquitination	1.930180e-3
GO:2000380	regulation of mesoderm development	2.003556e-3
GO:0048852	diencephalon morphogenesis	2.003556e-3
GO:0051964	negative regulation of synapse assembly	2.025640e-3
GO:0003254	regulation of membrane depolarization	2.063438e-3
GO:0060764	cell-cell signaling involved in mammary gland development	2.121458e-3
GO:0060379	cardiac muscle cell myoblast differentiation	2.121458e-3
GO:0003127	detection of nodal flow	2.121458e-3
GO:0031129	inductive cell-cell signaling	2.121458e-3
GO:0034551	mitochondrial respiratory chain complex III assembly	2.121458e-3
GO:0030262	apoptotic nuclear change	2.130998e-3
GO:0072098	anterior/posterior pattern specification involved in kidney development	2.136514e-3
GO:0048389	intermediate mesoderm development	2.136514e-3
GO:0007412	axon target recognition	2.136514e-3
GO:0031018	endocrine pancreas development	2.158993e-3
GO:0060749	mammary gland alveolus development	2.178388e-3
GO:0060606	tube closure	2.255969e-3
GO:0046653	tetrahydrofolate metabolic process	2.285208e-3
GO:0003166	bundle of His development	2.285208e-3
GO:0035148	tube formation	2.285772e-3
GO:0034660	ncRNA metabolic process	2.300080e-3
GO:0051961	negative regulation of nervous system development	2.371330e-3
GO:0050665	hydrogen peroxide biosynthetic process	2.371330e-3
GO:0006085	acetyl-CoA biosynthetic process	2.371330e-3
GO:0051642	centrosome localization	2.389916e-3
GO:0042490	mechanoreceptor differentiation	2.396356e-3
GO:0034698	response to gonadotropin stimulus	2.422071e-3
GO:0006610	ribosomal protein import into nucleus	2.452380e-3
GO:0060045	positive regulation of cardiac muscle cell proliferation	2.459293e-3
GO:0032439	endosome localization	2.461695e-3
GO:0031104	dendrite regeneration	2.461695e-3
GO:0060603	mammary gland duct morphogenesis	2.491132e-3
GO:0050922	negative regulation of chemotaxis	2.524404e-3
GO:0051052	regulation of DNA metabolic process	2.538600e-3
GO:0000209	protein polyubiquitination	2.583064e-3
GO:0030825	positive regulation of cGMP metabolic process	2.596421e-3
GO:0072203	cell proliferation involved in metanephros development	2.596421e-3
GO:0006916	anti-apoptosis	2.610228e-3
GO:0043401	steroid hormone mediated signaling pathway	2.621624e-3
GO:0031572	G2/M transition DNA damage checkpoint	2.631613e-3
GO:0043162	ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway	2.658930e-3
GO:0046755	non-lytic virus budding	2.658930e-3
GO:0000077	DNA damage checkpoint	2.703048e-3
GO:0048732	gland development	2.717465e-3
GO:0046449	creatinine metabolic process	2.729786e-3
GO:0043217	myelin maintenance	2.759584e-3
GO:0070286	axonemal dynein complex assembly	2.798895e-3
GO:0048598	embryonic morphogenesis	2.975967e-3
GO:0000413	protein peptidyl-prolyl isomerization	2.978551e-3
GO:0000710	meiotic mismatch repair	2.996302e-3
GO:0043276	anoikis	2.996302e-3
GO:0031128	developmental induction	3.090656e-3
GO:0006334	nucleosome assembly	3.141056e-3
GO:0034470	ncRNA processing	3.142927e-3
GO:0045599	negative regulation of fat cell differentiation	3.168217e-3
GO:0045766	positive regulation of angiogenesis	3.176904e-3
GO:0072166	posterior mesonephric tubule development	3.177465e-3
GO:0032347	regulation of aldosterone biosynthetic process	3.177465e-3
GO:0071044	histone mRNA catabolic process	3.193548e-3
GO:0050869	negative regulation of B cell activation	3.233030e-3
GO:0034508	centromere complex assembly	3.281084e-3
GO:0061326	renal tubule development	3.355298e-3
GO:0071480	cellular response to gamma radiation	3.428668e-3
GO:0031570	DNA integrity checkpoint	3.540049e-3
GO:0046590	embryonic leg morphogenesis	3.584821e-3
GO:0030278	regulation of ossification	3.605828e-3
GO:0001841	neural tube formation	3.712213e-3
GO:0003219	cardiac right ventricle formation	3.727504e-3
GO:0045934	negative regulation of nucleobase-containing compound metabolic process	3.751863e-3
GO:0043487	regulation of RNA stability	3.757664e-3
GO:0006921	cellular component disassembly involved in apoptosis	3.842428e-3
GO:0009948	anterior/posterior axis specification	3.848828e-3
GO:0060113	inner ear receptor cell differentiation	3.865839e-3
GO:0008334	histone mRNA metabolic process	3.947515e-3
GO:0003061	positive regulation of the force of heart contraction by norepinephrine	3.967253e-3
GO:0060480	lung goblet cell differentiation	3.967253e-3
GO:0061051	positive regulation of cell growth involved in cardiac muscle cell development	3.967253e-3
GO:0010157	response to chlorate	3.967253e-3
GO:2000351	regulation of endothelial cell apoptosis	3.994636e-3
GO:0090102	cochlea development	4.000464e-3
GO:0006986	response to unfolded protein	4.007557e-3
GO:0048378	regulation of lateral mesodermal cell fate specification	4.036262e-3
GO:0006269	DNA replication, synthesis of RNA primer	4.036262e-3
GO:0030862	positive regulation of polarized epithelial cell differentiation	4.046883e-3
GO:0022414	reproductive process	4.105979e-3
GO:0022029	telencephalon cell migration	4.186104e-3
GO:0042981	regulation of apoptosis	4.195371e-3
GO:0060420	regulation of heart growth	4.205443e-3
GO:0043067	regulation of programmed cell death	4.247183e-3