Novel motif:135

name:	motif135_TNKYTGCAKA

Association to promoter expression in human samples<b>Summary:</b>Significance of the correlation with CAGE expression, human <br><b>Analyst:</b> Michiel de Hoon<br><br>link to source dataset <br>data

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Association to promoter expression in mouse samples <b>Summary:</b>Significance of the correlation with CAGE expression, mouse <br><b>Analyst:</b> Michiel de Hoon<br><br>link to source dataset <br>data

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GREAT analysis results for human <b>Summary:</b>Genomic Enrichment of Annotations Tool (GREAT, Nat Biotechnol. 2010 May;28(5):495-501) is used to identify, both in human and in mouse, the gene ontology terms of biological processes enriched given the predicted TFBSs, and evaluated the overlap in the top-500 gene ontology terms between human and mouse. For each novel motif, the P value for the overlap was then evaluated by calculating its relative rank with respect to this background distribution.<br>Analyst: Michiel de Hoon<br><br>link to source dataset <br>data

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GO ID	GO Term	p-value
GO:0032502	developmental process	1.309102e-15
GO:0007275	multicellular organismal development	2.002286e-15
GO:0032989	cellular component morphogenesis	2.140207e-15
GO:0050896	response to stimulus	9.715980e-15
GO:0014866	skeletal myofibril assembly	9.793700e-15
GO:0031032	actomyosin structure organization	7.018285e-14
GO:0032501	multicellular organismal process	2.495409e-13
GO:0031175	neuron projection development	2.582720e-13
GO:0048856	anatomical structure development	2.749784e-13
GO:0030241	skeletal muscle myosin thick filament assembly	3.107611e-13
GO:0048731	system development	5.697593e-13
GO:0000904	cell morphogenesis involved in differentiation	6.608388e-13
GO:0009653	anatomical structure morphogenesis	1.082995e-12
GO:0048468	cell development	1.538010e-12
GO:0000902	cell morphogenesis	4.032875e-12
GO:0048739	cardiac muscle fiber development	8.547802e-12
GO:0048812	neuron projection morphogenesis	1.011989e-11
GO:0065007	biological regulation	1.294517e-11
GO:0030239	myofibril assembly	2.133598e-11
GO:0060415	muscle tissue morphogenesis	4.127744e-11
GO:0006941	striated muscle contraction	4.735976e-11
GO:0030030	cell projection organization	5.046330e-11
GO:0007409	axonogenesis	8.776198e-11
GO:0050789	regulation of biological process	1.115918e-10
GO:0002682	regulation of immune system process	1.239431e-10
GO:0048667	cell morphogenesis involved in neuron differentiation	1.691610e-10
GO:0048858	cell projection morphogenesis	1.777643e-10
GO:0030240	skeletal muscle thin filament assembly	1.979745e-10
GO:0032990	cell part morphogenesis	2.289078e-10
GO:0030154	cell differentiation	6.185280e-10
GO:0048644	muscle organ morphogenesis	6.479863e-10
GO:0060296	regulation of cilium beat frequency involved in ciliary motility	7.072639e-10
GO:0055003	cardiac myofibril assembly	8.345408e-10
GO:0048747	muscle fiber development	9.028483e-10
GO:0055002	striated muscle cell development	1.124108e-9
GO:0007010	cytoskeleton organization	1.240178e-9
GO:0010927	cellular component assembly involved in morphogenesis	1.351125e-9
GO:0060537	muscle tissue development	1.584468e-9
GO:0006955	immune response	1.742640e-9
GO:0022008	neurogenesis	1.961622e-9
GO:0042692	muscle cell differentiation	2.050365e-9
GO:0048666	neuron development	2.272860e-9
GO:0055008	cardiac muscle tissue morphogenesis	2.348153e-9
GO:0030182	neuron differentiation	2.610840e-9
GO:0055001	muscle cell development	2.816677e-9
GO:0048869	cellular developmental process	3.485872e-9
GO:0071636	positive regulation of transforming growth factor beta production	3.861924e-9
GO:0051877	pigment granule aggregation in cell center	4.130212e-9
GO:0006068	ethanol catabolic process	4.170872e-9
GO:0048699	generation of neurons	4.505154e-9
GO:0009887	organ morphogenesis	4.596841e-9
GO:0045494	photoreceptor cell maintenance	5.064689e-9
GO:0030048	actin filament-based movement	5.163647e-9
GO:0009308	amine metabolic process	6.819241e-9
GO:0044106	cellular amine metabolic process	7.476968e-9
GO:0043954	cellular component maintenance	8.320361e-9
GO:0042060	wound healing	9.279794e-9
GO:0006911	phagocytosis, engulfment	9.286647e-9
GO:0007596	blood coagulation	9.332371e-9
GO:0060632	regulation of microtubule-based movement	9.589686e-9
GO:0007599	hemostasis	1.079427e-8
GO:0070831	basement membrane assembly	1.608342e-8
GO:0055013	cardiac muscle cell development	1.721229e-8
GO:0007399	nervous system development	2.073455e-8
GO:0051146	striated muscle cell differentiation	2.095174e-8
GO:0006069	ethanol oxidation	2.439002e-8
GO:0048769	sarcomerogenesis	2.537779e-8
GO:0032914	positive regulation of transforming growth factor beta1 production	2.769903e-8
GO:0050794	regulation of cellular process	3.052262e-8
GO:0002576	platelet degranulation	3.356205e-8
GO:0010759	positive regulation of macrophage chemotaxis	4.209921e-8
GO:0070252	actin-mediated cell contraction	4.355425e-8
GO:0003007	heart morphogenesis	4.673241e-8
GO:0030049	muscle filament sliding	4.745907e-8
GO:0045214	sarcomere organization	4.746694e-8
GO:0060027	convergent extension involved in gastrulation	5.914756e-8
GO:0010758	regulation of macrophage chemotaxis	6.585754e-8
GO:0009611	response to wounding	6.708429e-8
GO:0031099	regeneration	8.094811e-8
GO:0006520	cellular amino acid metabolic process	8.896642e-8
GO:0030036	actin cytoskeleton organization	1.009595e-7
GO:0042982	amyloid precursor protein metabolic process	1.011853e-7
GO:0030029	actin filament-based process	1.021142e-7
GO:0071622	regulation of granulocyte chemotaxis	1.037326e-7
GO:0021987	cerebral cortex development	1.260618e-7
GO:0031102	neuron projection regeneration	1.294611e-7
GO:0045579	positive regulation of B cell differentiation	1.309027e-7
GO:0001771	immunological synapse formation	1.329330e-7
GO:0071675	regulation of mononuclear cell migration	1.396852e-7
GO:0042747	circadian sleep/wake cycle, REM sleep	1.695384e-7
GO:0006928	cellular component movement	1.804259e-7
GO:0008628	induction of apoptosis by hormones	1.951908e-7
GO:0071634	regulation of transforming growth factor beta production	1.990542e-7
GO:0007507	heart development	1.999094e-7
GO:2000377	regulation of reactive oxygen species metabolic process	2.016151e-7
GO:0005981	regulation of glycogen catabolic process	2.106725e-7
GO:0000185	activation of MAPKKK activity	2.106725e-7
GO:0048646	anatomical structure formation involved in morphogenesis	2.224853e-7
GO:0050878	regulation of body fluid levels	2.284587e-7
GO:0048791	calcium ion-dependent exocytosis of neurotransmitter	2.611071e-7
GO:0006936	muscle contraction	2.673490e-7
GO:0006208	pyrimidine base catabolic process	3.411430e-7
GO:0043297	apical junction assembly	3.973995e-7
GO:0042221	response to chemical stimulus	4.281299e-7
GO:0040011	locomotion	4.490250e-7
GO:0006935	chemotaxis	4.767849e-7
GO:2000052	positive regulation of non-canonical Wnt receptor signaling pathway	4.815199e-7
GO:0048729	tissue morphogenesis	5.094243e-7
GO:0048738	cardiac muscle tissue development	6.083920e-7
GO:0007015	actin filament organization	6.176844e-7
GO:0071840	cellular component organization or biogenesis	7.784618e-7
GO:0070098	chemokine-mediated signaling pathway	7.790864e-7
GO:0050690	regulation of defense response to virus by virus	8.013679e-7
GO:0030335	positive regulation of cell migration	8.730744e-7
GO:0019752	carboxylic acid metabolic process	8.907484e-7
GO:0007154	cell communication	8.948397e-7
GO:0046113	nucleobase catabolic process	9.208855e-7
GO:2000145	regulation of cell motility	9.351200e-7
GO:0032908	regulation of transforming growth factor beta1 production	9.994914e-7
GO:0006732	coenzyme metabolic process	1.023415e-6
GO:0007076	mitotic chromosome condensation	1.053510e-6
GO:0002067	glandular epithelial cell differentiation	1.055395e-6
GO:2000147	positive regulation of cell motility	1.245583e-6
GO:0055007	cardiac muscle cell differentiation	1.248254e-6
GO:0042180	cellular ketone metabolic process	1.281006e-6
GO:0006082	organic acid metabolic process	1.305466e-6
GO:0002831	regulation of response to biotic stimulus	1.460142e-6
GO:0035058	nonmotile primary cilium assembly	1.541209e-6
GO:0050910	detection of mechanical stimulus involved in sensory perception of sound	1.624157e-6
GO:0030198	extracellular matrix organization	1.791090e-6
GO:0070830	tight junction assembly	1.841335e-6
GO:0014706	striated muscle tissue development	1.962091e-6
GO:0001890	placenta development	2.250164e-6
GO:0060263	regulation of respiratory burst	2.290280e-6
GO:0030431	sleep	2.332090e-6
GO:0040017	positive regulation of locomotion	2.373077e-6
GO:0023052	signaling	2.429368e-6
GO:0008037	cell recognition	2.483986e-6
GO:0071842	cellular component organization at cellular level	2.531061e-6
GO:0006749	glutathione metabolic process	2.646140e-6
GO:0007616	long-term memory	2.820277e-6
GO:0006790	sulfur compound metabolic process	2.895508e-6
GO:0001893	maternal placenta development	2.920541e-6
GO:0007499	ectoderm and mesoderm interaction	2.958442e-6
GO:2000096	positive regulation of Wnt receptor signaling pathway, planar cell polarity pathway	2.969502e-6
GO:0032886	regulation of microtubule-based process	2.974471e-6
GO:0072358	cardiovascular system development	3.009559e-6
GO:0016043	cellular component organization	3.213177e-6
GO:0006575	cellular modified amino acid metabolic process	3.255871e-6
GO:0007059	chromosome segregation	3.310222e-6
GO:0051270	regulation of cellular component movement	3.361280e-6
GO:0042178	xenobiotic catabolic process	3.409173e-6
GO:0007165	signal transduction	3.437224e-6
GO:0045112	integrin biosynthetic process	3.493203e-6
GO:0021615	glossopharyngeal nerve morphogenesis	3.514824e-6
GO:0030168	platelet activation	3.521692e-6
GO:0009605	response to external stimulus	3.589463e-6
GO:0007043	cell-cell junction assembly	3.648392e-6
GO:0007411	axon guidance	3.649826e-6
GO:2000831	regulation of steroid hormone secretion	3.826236e-6
GO:0030252	growth hormone secretion	3.868909e-6
GO:0071841	cellular component organization or biogenesis at cellular level	3.909714e-6
GO:0034329	cell junction assembly	4.276423e-6
GO:0009888	tissue development	4.280853e-6
GO:0051272	positive regulation of cellular component movement	4.367462e-6
GO:0040012	regulation of locomotion	4.585117e-6
GO:2000050	regulation of non-canonical Wnt receptor signaling pathway	4.872964e-6
GO:0030540	female genitalia development	5.109487e-6
GO:0002688	regulation of leukocyte chemotaxis	5.130802e-6
GO:0007416	synapse assembly	5.137784e-6
GO:0002690	positive regulation of leukocyte chemotaxis	5.349414e-6
GO:0051041	positive regulation of calcium-independent cell-cell adhesion	5.598500e-6
GO:0050902	leukocyte adhesive activation	5.598500e-6
GO:2000833	positive regulation of steroid hormone secretion	5.662380e-6
GO:0045666	positive regulation of neuron differentiation	5.962727e-6
GO:0021756	striatum development	6.105273e-6
GO:0048513	organ development	6.145969e-6
GO:0010646	regulation of cell communication	6.316651e-6
GO:0034205	beta-amyloid formation	6.477988e-6
GO:0048251	elastic fiber assembly	6.955647e-6
GO:0030277	maintenance of gastrointestinal epithelium	6.955647e-6
GO:0010748	negative regulation of plasma membrane long-chain fatty acid transport	7.567903e-6
GO:0008217	regulation of blood pressure	8.222849e-6
GO:0071392	cellular response to estradiol stimulus	8.275244e-6
GO:0010754	negative regulation of cGMP-mediated signaling	8.632442e-6
GO:0043652	engulfment of apoptotic cell	8.632442e-6
GO:0010751	negative regulation of nitric oxide mediated signal transduction	8.632442e-6
GO:0002605	negative regulation of dendritic cell antigen processing and presentation	8.632442e-6
GO:0002581	negative regulation of antigen processing and presentation of peptide or polysaccharide antigen via MHC class II	8.632442e-6
GO:0016101	diterpenoid metabolic process	8.858505e-6
GO:0003012	muscle system process	9.195537e-6
GO:0007155	cell adhesion	9.212217e-6
GO:0002687	positive regulation of leukocyte migration	9.925507e-6
GO:0022607	cellular component assembly	1.023651e-5
GO:0050795	regulation of behavior	1.044214e-5
GO:0051094	positive regulation of developmental process	1.101319e-5
GO:0002683	negative regulation of immune system process	1.122501e-5
GO:0030878	thyroid gland development	1.161107e-5
GO:0061061	muscle structure development	1.171614e-5
GO:0002685	regulation of leukocyte migration	1.198940e-5
GO:0006207	'de novo' pyrimidine base biosynthetic process	1.217329e-5
GO:0043900	regulation of multi-organism process	1.273108e-5
GO:0085029	extracellular matrix assembly	1.274923e-5
GO:0000819	sister chromatid segregation	1.290445e-5
GO:0060022	hard palate development	1.330872e-5
GO:0010746	regulation of plasma membrane long-chain fatty acid transport	1.368794e-5
GO:0021993	initiation of neural tube closure	1.442343e-5
GO:0046949	fatty-acyl-CoA biosynthetic process	1.487208e-5
GO:0006950	response to stress	1.497076e-5
GO:0032402	melanosome transport	1.499230e-5
GO:0061024	membrane organization	1.544221e-5
GO:0016044	cellular membrane organization	1.634474e-5
GO:0023051	regulation of signaling	1.668519e-5
GO:0010390	histone monoubiquitination	1.816442e-5
GO:0031103	axon regeneration	1.930293e-5
GO:0045597	positive regulation of cell differentiation	1.951890e-5
GO:0060259	regulation of feeding behavior	1.988999e-5
GO:0045216	cell-cell junction organization	2.036081e-5
GO:0006939	smooth muscle contraction	2.039664e-5
GO:0051918	negative regulation of fibrinolysis	2.059593e-5
GO:0006206	pyrimidine base metabolic process	2.157286e-5
GO:0045930	negative regulation of mitotic cell cycle	2.192032e-5
GO:0006710	androgen catabolic process	2.244464e-5
GO:0002376	immune system process	2.311937e-5
GO:0003008	system process	2.322100e-5
GO:0065008	regulation of biological quality	2.479996e-5
GO:0060525	prostate glandular acinus development	2.513925e-5
GO:0000070	mitotic sister chromatid segregation	2.599885e-5
GO:2000836	positive regulation of androgen secretion	2.684262e-5
GO:2000500	positive regulation of induction of apoptosis in response to chemical stimulus	2.684262e-5
GO:0030261	chromosome condensation	2.696835e-5
GO:0051129	negative regulation of cellular component organization	2.714128e-5
GO:0060529	squamous basal epithelial stem cell differentiation involved in prostate gland acinus development	2.749193e-5
GO:0035338	long-chain fatty-acyl-CoA biosynthetic process	2.855568e-5
GO:0034330	cell junction organization	2.881759e-5
GO:2000095	regulation of Wnt receptor signaling pathway, planar cell polarity pathway	3.022445e-5
GO:0010430	fatty acid omega-oxidation	3.090323e-5
GO:0090066	regulation of anatomical structure size	3.185446e-5
GO:0009988	cell-cell recognition	3.255904e-5
GO:0016081	synaptic vesicle docking involved in exocytosis	3.266488e-5
GO:0042058	regulation of epidermal growth factor receptor signaling pathway	3.400330e-5
GO:0051893	regulation of focal adhesion assembly	3.467991e-5
GO:0051904	pigment granule transport	3.637812e-5
GO:0050920	regulation of chemotaxis	3.790110e-5
GO:0009296	flagellum assembly	3.793935e-5
GO:0010669	epithelial structure maintenance	3.803877e-5
GO:0030838	positive regulation of actin filament polymerization	3.860925e-5
GO:2000252	negative regulation of feeding behavior	3.961908e-5
GO:0008015	blood circulation	3.962044e-5
GO:0043064	flagellum organization	4.071571e-5
GO:0015788	UDP-N-acetylglucosamine transport	4.076526e-5
GO:0030177	positive regulation of Wnt receptor signaling pathway	4.102114e-5
GO:0010977	negative regulation of neuron projection development	4.137309e-5
GO:0051917	regulation of fibrinolysis	4.137393e-5
GO:0061088	regulation of sequestering of zinc ion	4.195186e-5
GO:0061034	olfactory bulb mitral cell layer development	4.424341e-5
GO:0019859	thymine metabolic process	4.608342e-5
GO:0051895	negative regulation of focal adhesion assembly	4.617052e-5
GO:0001967	suckling behavior	4.694380e-5
GO:0050688	regulation of defense response to virus	4.694945e-5
GO:0035229	positive regulation of glutamate-cysteine ligase activity	4.850838e-5
GO:0060249	anatomical structure homeostasis	4.895586e-5
GO:0071844	cellular component assembly at cellular level	4.939286e-5
GO:0031347	regulation of defense response	4.947486e-5
GO:0048583	regulation of response to stimulus	5.347707e-5
GO:0050672	negative regulation of lymphocyte proliferation	5.406741e-5
GO:0007009	plasma membrane organization	5.489041e-5
GO:0030488	tRNA methylation	5.531185e-5
GO:0032851	positive regulation of Rab GTPase activity	5.565909e-5
GO:0051716	cellular response to stimulus	5.787357e-5
GO:0046320	regulation of fatty acid oxidation	5.857147e-5
GO:0048704	embryonic skeletal system morphogenesis	6.046467e-5
GO:0031114	regulation of microtubule depolymerization	6.276503e-5
GO:0006641	triglyceride metabolic process	6.375932e-5
GO:0044085	cellular component biogenesis	6.398813e-5
GO:0007517	muscle organ development	6.546723e-5
GO:0010955	negative regulation of protein processing	6.579054e-5
GO:0034605	cellular response to heat	6.656386e-5
GO:0031665	negative regulation of lipopolysaccharide-mediated signaling pathway	6.676715e-5
GO:0030334	regulation of cell migration	6.814322e-5
GO:0042483	negative regulation of odontogenesis	6.862166e-5
GO:0048520	positive regulation of behavior	6.887506e-5
GO:0060513	prostatic bud formation	7.555258e-5
GO:0045786	negative regulation of cell cycle	7.627786e-5
GO:0032401	establishment of melanosome localization	7.639933e-5
GO:0031345	negative regulation of cell projection organization	7.651739e-5
GO:0048246	macrophage chemotaxis	7.739935e-5
GO:0060694	regulation of cholesterol transporter activity	7.791135e-5
GO:0010388	cullin deneddylation	7.876938e-5
GO:0042535	positive regulation of tumor necrosis factor biosynthetic process	8.006945e-5
GO:0050709	negative regulation of protein secretion	8.390662e-5
GO:0010035	response to inorganic substance	8.837029e-5
GO:0006721	terpenoid metabolic process	8.944997e-5
GO:0031110	regulation of microtubule polymerization or depolymerization	9.088775e-5
GO:0051656	establishment of organelle localization	9.132971e-5
GO:0006518	peptide metabolic process	9.178553e-5
GO:0043536	positive regulation of blood vessel endothelial cell migration	9.341400e-5
GO:0070664	negative regulation of leukocyte proliferation	9.434696e-5
GO:0032369	negative regulation of lipid transport	9.502418e-5
GO:0051963	regulation of synapse assembly	9.596908e-5
GO:0042473	outer ear morphogenesis	9.791739e-5
GO:0050776	regulation of immune response	9.979105e-5
GO:0031129	inductive cell-cell signaling	9.987911e-5
GO:0006214	thymidine catabolic process	9.987911e-5
GO:0006097	glyoxylate cycle	9.987911e-5
GO:0031664	regulation of lipopolysaccharide-mediated signaling pathway	1.017922e-4
GO:0035239	tube morphogenesis	1.051097e-4
GO:2000310	regulation of N-methyl-D-aspartate selective glutamate receptor activity	1.052683e-4
GO:0007026	negative regulation of microtubule depolymerization	1.054570e-4
GO:0032273	positive regulation of protein polymerization	1.098639e-4
GO:0043242	negative regulation of protein complex disassembly	1.111720e-4
GO:0002604	regulation of dendritic cell antigen processing and presentation	1.112962e-4
GO:0002684	positive regulation of immune system process	1.121498e-4
GO:0009120	deoxyribonucleoside metabolic process	1.130879e-4
GO:0009408	response to heat	1.134055e-4
GO:0070482	response to oxygen levels	1.148421e-4
GO:0030595	leukocyte chemotaxis	1.171889e-4
GO:0043032	positive regulation of macrophage activation	1.198808e-4
GO:0009987	cellular process	1.208408e-4
GO:0042493	response to drug	1.233071e-4
GO:0071800	podosome assembly	1.236265e-4
GO:0060742	epithelial cell differentiation involved in prostate gland development	1.242804e-4
GO:0032271	regulation of protein polymerization	1.245834e-4
GO:0030194	positive regulation of blood coagulation	1.269301e-4
GO:0050921	positive regulation of chemotaxis	1.285275e-4
GO:0032091	negative regulation of protein binding	1.305462e-4
GO:0001775	cell activation	1.309613e-4
GO:0035051	cardiac cell differentiation	1.326143e-4
GO:0006996	organelle organization	1.348971e-4
GO:0032891	negative regulation of organic acid transport	1.369670e-4
GO:0034754	cellular hormone metabolic process	1.387328e-4
GO:0050707	regulation of cytokine secretion	1.412055e-4
GO:0009060	aerobic respiration	1.462975e-4
GO:0002369	T cell cytokine production	1.537535e-4
GO:0002673	regulation of acute inflammatory response	1.565026e-4
GO:0071394	cellular response to testosterone stimulus	1.567856e-4
GO:0045908	negative regulation of vasodilation	1.567856e-4
GO:0048075	positive regulation of eye pigmentation	1.567856e-4
GO:0051338	regulation of transferase activity	1.569733e-4
GO:0006542	glutamine biosynthetic process	1.570072e-4
GO:0051905	establishment of pigment granule localization	1.589061e-4
GO:0033523	histone H2B ubiquitination	1.623946e-4
GO:0045906	negative regulation of vasoconstriction	1.626450e-4
GO:0051186	cofactor metabolic process	1.640313e-4
GO:0032026	response to magnesium ion	1.664382e-4
GO:0050710	negative regulation of cytokine secretion	1.665917e-4
GO:0032400	melanosome localization	1.673585e-4
GO:0030857	negative regulation of epithelial cell differentiation	1.736210e-4
GO:0006212	uracil catabolic process	1.737461e-4
GO:0006210	thymine catabolic process	1.737461e-4
GO:0045859	regulation of protein kinase activity	1.769396e-4
GO:0051960	regulation of nervous system development	1.808653e-4
GO:0030859	polarized epithelial cell differentiation	1.815071e-4
GO:0021544	subpallium development	1.848643e-4
GO:0048745	smooth muscle tissue development	1.891351e-4
GO:0045577	regulation of B cell differentiation	1.934588e-4
GO:0045088	regulation of innate immune response	1.961078e-4
GO:0015904	tetracycline transport	1.963307e-4
GO:0006091	generation of precursor metabolites and energy	2.073054e-4
GO:0043549	regulation of kinase activity	2.123063e-4
GO:0015980	energy derivation by oxidation of organic compounds	2.132068e-4
GO:0003013	circulatory system process	2.146360e-4
GO:0006637	acyl-CoA metabolic process	2.270394e-4
GO:0060197	cloacal septation	2.272455e-4
GO:0010757	negative regulation of plasminogen activation	2.320548e-4
GO:0050808	synapse organization	2.324603e-4
GO:0002577	regulation of antigen processing and presentation	2.387487e-4
GO:0060381	positive regulation of single-stranded telomeric DNA binding	2.430402e-4
GO:0042489	negative regulation of odontogenesis of dentine-containing tooth	2.483563e-4
GO:0019217	regulation of fatty acid metabolic process	2.571293e-4
GO:0051179	localization	2.633860e-4
GO:0001523	retinoid metabolic process	2.690984e-4
GO:0033363	secretory granule organization	2.691102e-4
GO:0006907	pinocytosis	2.698274e-4
GO:0048807	female genitalia morphogenesis	2.711139e-4
GO:0031579	membrane raft organization	2.822474e-4
GO:0006639	acylglycerol metabolic process	2.851599e-4
GO:0002088	lens development in camera-type eye	2.898975e-4
GO:0060157	urinary bladder development	2.902455e-4
GO:0006434	seryl-tRNA aminoacylation	2.955449e-4
GO:0000066	mitochondrial ornithine transport	2.977323e-4
GO:0006099	tricarboxylic acid cycle	3.000927e-4
GO:0051234	establishment of localization	3.059716e-4
GO:0070544	histone H3-K36 demethylation	3.072239e-4
GO:0050820	positive regulation of coagulation	3.077665e-4
GO:0010310	regulation of hydrogen peroxide metabolic process	3.080261e-4
GO:0051875	pigment granule localization	3.124320e-4
GO:0046356	acetyl-CoA catabolic process	3.235320e-4
GO:0050435	beta-amyloid metabolic process	3.250413e-4
GO:0006638	neutral lipid metabolic process	3.442730e-4
GO:0051650	establishment of vesicle localization	3.499188e-4
GO:0046476	glycosylceramide biosynthetic process	3.616847e-4
GO:0035357	peroxisome proliferator activated receptor signaling pathway	3.616847e-4
GO:0006887	exocytosis	3.778810e-4
GO:0050803	regulation of synapse structure and activity	3.797641e-4
GO:0015887	pantothenate transmembrane transport	3.818855e-4
GO:0015878	biotin transport	3.818855e-4
GO:0006679	glucosylceramide biosynthetic process	3.853843e-4
GO:0051409	response to nitrosative stress	4.012749e-4
GO:0022037	metencephalon development	4.060048e-4
GO:0048584	positive regulation of response to stimulus	4.142605e-4
GO:0009108	coenzyme biosynthetic process	4.241244e-4
GO:0010755	regulation of plasminogen activation	4.277419e-4
GO:0031122	cytoplasmic microtubule organization	4.290357e-4
GO:0048073	regulation of eye pigmentation	4.345240e-4
GO:0070672	response to interleukin-15	4.350219e-4
GO:0016574	histone ubiquitination	4.356875e-4
GO:0050807	regulation of synapse organization	4.406140e-4
GO:0009790	embryo development	4.555150e-4
GO:0060548	negative regulation of cell death	4.578842e-4
GO:0001666	response to hypoxia	4.588994e-4
GO:0001819	positive regulation of cytokine production	4.594392e-4
GO:0043623	cellular protein complex assembly	4.708580e-4
GO:0046121	deoxyribonucleoside catabolic process	4.766867e-4
GO:0001867	complement activation, lectin pathway	4.858169e-4
GO:0002832	negative regulation of response to biotic stimulus	4.921612e-4
GO:0033861	negative regulation of NAD(P)H oxidase activity	4.993923e-4
GO:0030327	prenylated protein catabolic process	4.993923e-4
GO:0009582	detection of abiotic stimulus	5.013583e-4
GO:0006805	xenobiotic metabolic process	5.015049e-4
GO:0060055	angiogenesis involved in wound healing	5.019789e-4
GO:0006145	purine base catabolic process	5.031192e-4
GO:0022603	regulation of anatomical structure morphogenesis	5.034239e-4
GO:0006952	defense response	5.146247e-4
GO:0001812	positive regulation of type I hypersensitivity	5.184405e-4
GO:0045617	negative regulation of keratinocyte differentiation	5.225738e-4
GO:0044281	small molecule metabolic process	5.243336e-4
GO:0043069	negative regulation of programmed cell death	5.264229e-4
GO:0009792	embryo development ending in birth or egg hatching	5.394541e-4
GO:0007613	memory	5.422655e-4
GO:0010763	positive regulation of fibroblast migration	5.562145e-4
GO:0009967	positive regulation of signal transduction	5.643260e-4
GO:0009966	regulation of signal transduction	5.712029e-4
GO:0016192	vesicle-mediated transport	5.814551e-4
GO:0001654	eye development	5.816880e-4
GO:0048562	embryonic organ morphogenesis	5.848984e-4
GO:0022414	reproductive process	5.907308e-4
GO:0043471	regulation of cellular carbohydrate catabolic process	5.924318e-4
GO:0031100	organ regeneration	6.025839e-4
GO:0032094	response to food	6.057835e-4
GO:0002694	regulation of leukocyte activation	6.112272e-4
GO:0046104	thymidine metabolic process	6.196384e-4
GO:0042733	embryonic digit morphogenesis	6.289573e-4
GO:0045444	fat cell differentiation	6.314669e-4
GO:0009066	aspartate family amino acid metabolic process	6.323190e-4
GO:0060026	convergent extension	6.487430e-4
GO:0001763	morphogenesis of a branching structure	6.495787e-4
GO:0021678	third ventricle development	6.525717e-4
GO:0010647	positive regulation of cell communication	6.592630e-4
GO:0072079	nephron tubule formation	6.746881e-4
GO:0021858	GABAergic neuron differentiation in basal ganglia	6.768919e-4
GO:0048870	cell motility	6.794986e-4
GO:0034370	triglyceride-rich lipoprotein particle remodeling	6.829865e-4
GO:0010464	regulation of mesenchymal cell proliferation	6.921105e-4
GO:0006766	vitamin metabolic process	6.923017e-4
GO:0071466	cellular response to xenobiotic stimulus	7.090839e-4
GO:0042534	regulation of tumor necrosis factor biosynthetic process	7.195810e-4
GO:0043066	negative regulation of apoptosis	7.206767e-4
GO:0045324	late endosome to vacuole transport	7.304075e-4
GO:0046947	hydroxylysine biosynthetic process	7.304075e-4
GO:0045234	protein palmitoleylation	7.304075e-4
GO:0006948	induction by virus of host cell-cell fusion	7.304075e-4
GO:0002053	positive regulation of mesenchymal cell proliferation	7.316503e-4
GO:0046716	muscle cell homeostasis	7.339912e-4
GO:0016477	cell migration	7.347182e-4
GO:0032571	response to vitamin K	7.376013e-4
GO:0006497	protein lipidation	7.388775e-4
GO:0021549	cerebellum development	7.396980e-4
GO:0030833	regulation of actin filament polymerization	7.496914e-4
GO:0009109	coenzyme catabolic process	7.539657e-4
GO:0030856	regulation of epithelial cell differentiation	7.551689e-4
GO:0000003	reproduction	7.627063e-4
GO:0033211	adiponectin-mediated signaling pathway	7.636626e-4
GO:0000096	sulfur amino acid metabolic process	7.723003e-4
GO:0023056	positive regulation of signaling	7.745064e-4
GO:0051303	establishment of chromosome localization	7.785122e-4
GO:0016358	dendrite development	7.841086e-4
GO:0034097	response to cytokine stimulus	7.912388e-4
GO:0060326	cell chemotaxis	7.928882e-4
GO:0000271	polysaccharide biosynthetic process	8.036125e-4
GO:0045818	negative regulation of glycogen catabolic process	8.077073e-4
GO:0072006	nephron development	8.117208e-4
GO:2000378	negative regulation of reactive oxygen species metabolic process	8.181518e-4
GO:0043403	skeletal muscle tissue regeneration	8.181518e-4
GO:0033006	regulation of mast cell activation involved in immune response	8.204408e-4
GO:0001894	tissue homeostasis	8.228152e-4
GO:0045143	homologous chromosome segregation	8.309402e-4
GO:0071872	cellular response to epinephrine stimulus	8.438290e-4
GO:0070613	regulation of protein processing	8.616051e-4
GO:0045766	positive regulation of angiogenesis	8.685460e-4
GO:0043010	camera-type eye development	8.905683e-4
GO:0070076	histone lysine demethylation	8.907904e-4
GO:0046464	acylglycerol catabolic process	8.952305e-4
GO:0050865	regulation of cell activation	8.999657e-4
GO:0035042	fertilization, exchange of chromosomal proteins	9.331225e-4
GO:0002674	negative regulation of acute inflammatory response	9.335205e-4
GO:0021860	pyramidal neuron development	9.395647e-4
GO:0032695	negative regulation of interleukin-12 production	9.521173e-4
GO:0051289	protein homotetramerization	9.676414e-4
GO:0006954	inflammatory response	9.718171e-4

GREAT analysis results for mouseGenomic Enrichment of Annotations Tool (GREAT, Nat Biotechnol. 2010 May;28(5):495-501) is used to identify, both in human and in mouse, the gene ontology terms of biological processes enriched given the predicted TFBSs, and evaluated the overlap in the top-500 gene ontology terms between human and mouse. For each novel motif, the P value for the overlap was then evaluated by calculating its relative rank with respect to this background distribution.<br>Analyst: Michiel de Hoon <br><br>link to source dataset <br>data

---

GO ID	GO Term	p-value
GO:0042271	susceptibility to natural killer cell mediated cytotoxicity	9.184825e-13
GO:0016074	snoRNA metabolic process	3.751885e-10
GO:0005996	monosaccharide metabolic process	6.304145e-9
GO:0018108	peptidyl-tyrosine phosphorylation	8.795946e-9
GO:0046164	alcohol catabolic process	5.318516e-8
GO:0019318	hexose metabolic process	8.795750e-8
GO:0009612	response to mechanical stimulus	1.417786e-7
GO:0060135	maternal process involved in female pregnancy	1.517727e-7
GO:0006006	glucose metabolic process	1.621271e-7
GO:0048386	positive regulation of retinoic acid receptor signaling pathway	1.895002e-7
GO:0042269	regulation of natural killer cell mediated cytotoxicity	2.765767e-7
GO:0046365	monosaccharide catabolic process	2.875950e-7
GO:0060745	mammary gland branching involved in pregnancy	3.042487e-7
GO:0031129	inductive cell-cell signaling	3.200006e-7
GO:0045954	positive regulation of natural killer cell mediated cytotoxicity	3.324222e-7
GO:0043032	positive regulation of macrophage activation	6.443378e-7
GO:0048730	epidermis morphogenesis	6.634604e-7
GO:0060065	uterus development	9.879802e-7
GO:0090273	regulation of somatostatin secretion	1.019285e-6
GO:0030177	positive regulation of Wnt receptor signaling pathway	1.179680e-6
GO:0051770	positive regulation of nitric-oxide synthase biosynthetic process	1.252460e-6
GO:0071360	cellular response to exogenous dsRNA	1.252460e-6
GO:0015747	urate transport	1.330071e-6
GO:0001970	positive regulation of activation of membrane attack complex	1.380283e-6
GO:0035584	calcium-mediated signaling using intracellular calcium source	1.725322e-6
GO:0042345	regulation of NF-kappaB import into nucleus	1.914286e-6
GO:0019320	hexose catabolic process	1.988715e-6
GO:0032571	response to vitamin K	2.310751e-6
GO:0044275	cellular carbohydrate catabolic process	2.364519e-6
GO:0019255	glucose 1-phosphate metabolic process	2.649209e-6
GO:0051704	multi-organism process	2.738428e-6
GO:0043589	skin morphogenesis	2.802086e-6
GO:0010226	response to lithium ion	2.988449e-6
GO:0001969	regulation of activation of membrane attack complex	3.024964e-6
GO:0048584	positive regulation of response to stimulus	3.150316e-6
GO:0006098	pentose-phosphate shunt	4.191606e-6
GO:0048545	response to steroid hormone stimulus	4.566425e-6
GO:0044262	cellular carbohydrate metabolic process	4.791279e-6
GO:0042346	positive regulation of NF-kappaB import into nucleus	4.932282e-6
GO:0031032	actomyosin structure organization	5.298894e-6
GO:0060231	mesenchymal to epithelial transition	5.379681e-6
GO:0001547	antral ovarian follicle growth	6.158139e-6
GO:0009967	positive regulation of signal transduction	6.377527e-6
GO:0045088	regulation of innate immune response	6.539667e-6
GO:0009258	10-formyltetrahydrofolate catabolic process	8.547645e-6
GO:2000380	regulation of mesoderm development	8.553151e-6
GO:0007166	cell surface receptor linked signaling pathway	8.694857e-6
GO:0060011	Sertoli cell proliferation	1.044218e-5
GO:0051769	regulation of nitric-oxide synthase biosynthetic process	1.070067e-5
GO:0006739	NADP metabolic process	1.100245e-5
GO:0015851	nucleobase transport	1.140322e-5
GO:0072077	renal vesicle morphogenesis	1.160114e-5
GO:0001833	inner cell mass cell proliferation	1.160114e-5
GO:0006007	glucose catabolic process	1.318985e-5
GO:0003337	mesenchymal to epithelial transition involved in metanephros morphogenesis	1.348567e-5
GO:0045089	positive regulation of innate immune response	1.350505e-5
GO:0045766	positive regulation of angiogenesis	1.436225e-5
GO:0035356	cellular triglyceride homeostasis	1.472873e-5
GO:0030239	myofibril assembly	1.522150e-5
GO:0030520	estrogen receptor signaling pathway	1.539949e-5
GO:0007565	female pregnancy	1.615752e-5
GO:0007010	cytoskeleton organization	1.685928e-5
GO:0045429	positive regulation of nitric oxide biosynthetic process	1.698252e-5
GO:2000381	negative regulation of mesoderm development	1.990447e-5
GO:0060750	epithelial cell proliferation involved in mammary gland duct elongation	2.134964e-5
GO:0072033	renal vesicle formation	2.270751e-5
GO:0048583	regulation of response to stimulus	2.323401e-5
GO:0031936	negative regulation of chromatin silencing	2.383484e-5
GO:0090072	positive regulation of sodium ion transport via voltage-gated sodium channel activity	2.564525e-5
GO:0010717	regulation of epithelial to mesenchymal transition	2.826375e-5
GO:0060837	blood vessel endothelial cell differentiation	2.856489e-5
GO:0010954	positive regulation of protein processing	2.982174e-5
GO:0050847	progesterone receptor signaling pathway	3.020052e-5
GO:0031341	regulation of cell killing	3.119368e-5
GO:0042511	positive regulation of tyrosine phosphorylation of Stat1 protein	3.222399e-5
GO:0030505	inorganic diphosphate transport	3.264560e-5
GO:2000384	negative regulation of ectoderm development	3.264560e-5
GO:0009116	nucleoside metabolic process	3.530089e-5
GO:0009225	nucleotide-sugar metabolic process	3.554025e-5
GO:0060828	regulation of canonical Wnt receptor signaling pathway	3.604905e-5
GO:0060969	negative regulation of gene silencing	3.726550e-5
GO:0006863	purine base transport	3.726550e-5
GO:0032814	regulation of natural killer cell activation	4.000917e-5
GO:0023056	positive regulation of signaling	4.109355e-5
GO:0042510	regulation of tyrosine phosphorylation of Stat1 protein	4.236814e-5
GO:0031935	regulation of chromatin silencing	4.294872e-5
GO:0010647	positive regulation of cell communication	4.319874e-5
GO:0060968	regulation of gene silencing	4.358131e-5
GO:0043569	negative regulation of insulin-like growth factor receptor signaling pathway	4.505419e-5
GO:0030518	steroid hormone receptor signaling pathway	4.681827e-5
GO:0002053	positive regulation of mesenchymal cell proliferation	4.746264e-5
GO:0045839	negative regulation of mitosis	4.826249e-5
GO:0043627	response to estrogen stimulus	4.827855e-5
GO:0016052	carbohydrate catabolic process	4.839789e-5
GO:0051127	positive regulation of actin nucleation	5.122317e-5
GO:0010035	response to inorganic substance	5.285412e-5
GO:0003338	metanephros morphogenesis	5.352314e-5
GO:0009119	ribonucleoside metabolic process	5.690262e-5
GO:0001910	regulation of leukocyte mediated cytotoxicity	5.733740e-5
GO:0017187	peptidyl-glutamic acid carboxylation	5.783256e-5
GO:0009443	pyridoxal 5'-phosphate salvage	5.783256e-5
GO:0001656	metanephros development	5.900313e-5
GO:0048630	skeletal muscle tissue growth	5.995373e-5
GO:0044282	small molecule catabolic process	6.090219e-5
GO:2000383	regulation of ectoderm development	6.324472e-5
GO:0006936	muscle contraction	6.415273e-5
GO:0090263	positive regulation of canonical Wnt receptor signaling pathway	6.440384e-5
GO:0045919	positive regulation of cytolysis	6.730232e-5
GO:0031349	positive regulation of defense response	6.836773e-5
GO:0002699	positive regulation of immune effector process	7.045306e-5
GO:0080111	DNA demethylation	7.480438e-5
GO:0072087	renal vesicle development	7.994382e-5
GO:0030449	regulation of complement activation	8.728041e-5
GO:0051656	establishment of organelle localization	8.848547e-5
GO:0006882	cellular zinc ion homeostasis	9.174799e-5
GO:0060068	vagina development	9.246960e-5
GO:0010641	positive regulation of platelet-derived growth factor receptor signaling pathway	9.400363e-5
GO:0072283	metanephric renal vesicle morphogenesis	9.815788e-5
GO:0060751	branch elongation involved in mammary gland duct branching	9.838206e-5
GO:0060452	positive regulation of cardiac muscle contraction	1.006809e-4
GO:0072273	metanephric nephron morphogenesis	1.046750e-4
GO:0003012	muscle system process	1.064628e-4
GO:0048511	rhythmic process	1.103189e-4
GO:0002920	regulation of humoral immune response	1.109938e-4
GO:0043030	regulation of macrophage activation	1.111215e-4
GO:0051260	protein homooligomerization	1.133659e-4
GO:0001832	blastocyst growth	1.198089e-4
GO:0002293	alpha-beta T cell differentiation involved in immune response	1.236140e-4
GO:0042531	positive regulation of tyrosine phosphorylation of STAT protein	1.270222e-4
GO:0060523	prostate epithelial cord elongation	1.348265e-4
GO:0071310	cellular response to organic substance	1.349534e-4
GO:0055069	zinc ion homeostasis	1.363421e-4
GO:0035234	germ cell programmed cell death	1.409287e-4
GO:0010740	positive regulation of intracellular protein kinase cascade	1.519978e-4
GO:0002287	alpha-beta T cell activation involved in immune response	1.525103e-4
GO:0030240	skeletal muscle thin filament assembly	1.525103e-4
GO:0007186	G-protein coupled receptor protein signaling pathway	1.567093e-4
GO:0048339	paraxial mesoderm development	1.579689e-4
GO:0031069	hair follicle morphogenesis	1.595645e-4
GO:0032700	negative regulation of interleukin-17 production	1.687539e-4
GO:0032496	response to lipopolysaccharide	1.687867e-4
GO:0030879	mammary gland development	1.818611e-4
GO:0042993	positive regulation of transcription factor import into nucleus	1.993055e-4
GO:0042990	regulation of transcription factor import into nucleus	2.011903e-4
GO:0072088	nephron epithelium morphogenesis	2.015620e-4
GO:0090310	negative regulation of methylation-dependent chromatin silencing	2.055352e-4
GO:0060427	lung connective tissue development	2.055352e-4
GO:0006000	fructose metabolic process	2.108702e-4
GO:0045428	regulation of nitric oxide biosynthetic process	2.210061e-4
GO:0030111	regulation of Wnt receptor signaling pathway	2.221578e-4
GO:0009826	unidimensional cell growth	2.239723e-4
GO:0072092	ureteric bud invasion	2.239723e-4
GO:0055080	cation homeostasis	2.308947e-4
GO:0005975	carbohydrate metabolic process	2.362461e-4
GO:0006044	N-acetylglucosamine metabolic process	2.377006e-4
GO:0031343	positive regulation of cell killing	2.388548e-4
GO:0010623	developmental programmed cell death	2.409586e-4
GO:0031347	regulation of defense response	2.443886e-4
GO:0006925	inflammatory cell apoptosis	2.543854e-4
GO:0060658	nipple morphogenesis	2.543854e-4
GO:0002237	response to molecule of bacterial origin	2.544667e-4
GO:0060444	branching involved in mammary gland duct morphogenesis	2.585945e-4
GO:0097118	neuroligin clustering	2.589372e-4
GO:0030036	actin cytoskeleton organization	2.589495e-4
GO:0051707	response to other organism	2.657144e-4
GO:0010038	response to metal ion	2.681515e-4
GO:0070206	protein trimerization	2.725407e-4
GO:0007219	Notch signaling pathway	2.796942e-4
GO:0035510	DNA dealkylation	2.910523e-4
GO:0032648	regulation of interferon-beta production	2.941400e-4
GO:0071947	protein deubiquitination involved in ubiquitin-dependent protein catabolic process	2.965473e-4
GO:0051259	protein oligomerization	3.080464e-4
GO:0050801	ion homeostasis	3.095504e-4
GO:0046427	positive regulation of JAK-STAT cascade	3.168136e-4
GO:0006040	amino sugar metabolic process	3.309101e-4
GO:0009120	deoxyribonucleoside metabolic process	3.419041e-4
GO:0006955	immune response	3.476391e-4
GO:0019882	antigen processing and presentation	3.498858e-4
GO:0010770	positive regulation of cell morphogenesis involved in differentiation	3.529686e-4
GO:0046415	urate metabolic process	3.572083e-4
GO:0051128	regulation of cellular component organization	3.769822e-4
GO:0042421	norepinephrine biosynthetic process	3.835261e-4
GO:0009628	response to abiotic stimulus	3.889047e-4
GO:0060749	mammary gland alveolus development	3.954770e-4
GO:0010260	organ senescence	3.965275e-4
GO:0015746	citrate transport	3.965275e-4
GO:0070278	extracellular matrix constituent secretion	3.965275e-4
GO:0010273	detoxification of copper ion	3.965275e-4
GO:0033865	nucleoside bisphosphate metabolic process	3.975801e-4
GO:0061034	olfactory bulb mitral cell layer development	4.059970e-4
GO:0002706	regulation of lymphocyte mediated immunity	4.152138e-4
GO:0043330	response to exogenous dsRNA	4.236661e-4
GO:0030261	chromosome condensation	4.348338e-4
GO:0010464	regulation of mesenchymal cell proliferation	4.382228e-4
GO:0001912	positive regulation of leukocyte mediated cytotoxicity	4.418049e-4
GO:0019276	UDP-N-acetylgalactosamine metabolic process	4.545450e-4
GO:0009966	regulation of signal transduction	4.559719e-4
GO:0060443	mammary gland morphogenesis	4.616066e-4
GO:0072093	metanephric renal vesicle formation	4.657802e-4
GO:0030101	natural killer cell activation	4.685111e-4
GO:0002682	regulation of immune system process	4.690751e-4
GO:0090274	positive regulation of somatostatin secretion	4.787207e-4
GO:0010718	positive regulation of epithelial to mesenchymal transition	4.824816e-4
GO:0009887	organ morphogenesis	4.903960e-4
GO:0071260	cellular response to mechanical stimulus	5.095246e-4
GO:0031214	biomineral tissue development	5.115894e-4
GO:0071899	negative regulation of estrogen receptor binding	5.182113e-4
GO:0033141	positive regulation of peptidyl-serine phosphorylation of STAT protein	5.184422e-4
GO:0000003	reproduction	5.193682e-4
GO:0042523	positive regulation of tyrosine phosphorylation of Stat5 protein	5.219461e-4
GO:0007567	parturition	5.331877e-4
GO:0022414	reproductive process	5.415408e-4
GO:0051186	cofactor metabolic process	5.436863e-4
GO:0045742	positive regulation of epidermal growth factor receptor signaling pathway	5.486589e-4
GO:0070372	regulation of ERK1 and ERK2 cascade	5.512333e-4
GO:0097116	gephyrin clustering	5.559213e-4
GO:0046939	nucleotide phosphorylation	5.592421e-4
GO:0042093	T-helper cell differentiation	5.592421e-4
GO:0070887	cellular response to chemical stimulus	5.772456e-4
GO:0030029	actin filament-based process	5.872028e-4
GO:0032355	response to estradiol stimulus	6.090933e-4
GO:0022604	regulation of cell morphogenesis	6.137189e-4
GO:0032964	collagen biosynthetic process	6.278944e-4
GO:0048385	regulation of retinoic acid receptor signaling pathway	6.329473e-4
GO:0046688	response to copper ion	6.394898e-4
GO:0007172	signal complex assembly	6.420109e-4
GO:0030838	positive regulation of actin filament polymerization	6.534382e-4
GO:0042306	regulation of protein import into nucleus	6.625075e-4
GO:0002064	epithelial cell development	6.742390e-4
GO:0051272	positive regulation of cellular component movement	6.891539e-4
GO:0032816	positive regulation of natural killer cell activation	6.903171e-4
GO:0009607	response to biotic stimulus	7.069937e-4
GO:2000147	positive regulation of cell motility	7.133860e-4
GO:0045765	regulation of angiogenesis	7.144461e-4
GO:0021889	olfactory bulb interneuron differentiation	7.234467e-4
GO:0006826	iron ion transport	7.293307e-4
GO:0043588	skin development	7.321161e-4
GO:0048754	branching morphogenesis of a tube	7.356824e-4
GO:0002708	positive regulation of lymphocyte mediated immunity	7.445197e-4
GO:0019428	allantoin biosynthetic process	7.519515e-4
GO:0001649	osteoblast differentiation	7.711024e-4
GO:0021553	olfactory nerve development	7.762971e-4
GO:0043567	regulation of insulin-like growth factor receptor signaling pathway	7.826918e-4
GO:0014866	skeletal myofibril assembly	7.866265e-4
GO:0072028	nephron morphogenesis	7.950635e-4
GO:0007566	embryo implantation	8.145924e-4
GO:0045214	sarcomere organization	8.206574e-4
GO:0042509	regulation of tyrosine phosphorylation of STAT protein	8.276515e-4
GO:0001763	morphogenesis of a branching structure	8.349059e-4
GO:0002703	regulation of leukocyte mediated immunity	8.359742e-4
GO:0034059	response to anoxia	8.382036e-4
GO:0010627	regulation of intracellular protein kinase cascade	8.588888e-4
GO:0008544	epidermis development	8.670347e-4
GO:0035137	hindlimb morphogenesis	8.678497e-4
GO:0002318	myeloid progenitor cell differentiation	8.737919e-4
GO:0032119	sequestering of zinc ion	8.820312e-4
GO:0008588	release of cytoplasmic sequestered NF-kappaB	8.824387e-4
GO:0022603	regulation of anatomical structure morphogenesis	8.899060e-4
GO:0071495	cellular response to endogenous stimulus	8.902585e-4
GO:0009617	response to bacterium	8.964362e-4
GO:0002866	positive regulation of acute inflammatory response to antigenic stimulus	9.444303e-4
GO:0080134	regulation of response to stress	9.558370e-4
GO:0070848	response to growth factor stimulus	9.669255e-4
GO:0051964	negative regulation of synapse assembly	9.700500e-4
GO:0006165	nucleoside diphosphate phosphorylation	9.700500e-4
GO:0006228	UTP biosynthetic process	9.700500e-4
GO:0006732	coenzyme metabolic process	9.781994e-4
GO:0043503	skeletal muscle fiber adaptation	9.816949e-4
GO:0001826	inner cell mass cell differentiation	9.816949e-4
GO:0032667	regulation of interleukin-23 production	9.816949e-4
GO:0055062	phosphate ion homeostasis	1.005494e-3
GO:0030522	intracellular receptor mediated signaling pathway	1.011587e-3
GO:0034505	tooth mineralization	1.022050e-3
GO:0007004	telomere maintenance via telomerase	1.041173e-3
GO:0009220	pyrimidine ribonucleotide biosynthetic process	1.066682e-3
GO:0032479	regulation of type I interferon production	1.075533e-3
GO:0010810	regulation of cell-substrate adhesion	1.078315e-3
GO:0002689	negative regulation of leukocyte chemotaxis	1.098864e-3
GO:0018214	protein carboxylation	1.107335e-3
GO:0018193	peptidyl-amino acid modification	1.120291e-3
GO:0006213	pyrimidine nucleoside metabolic process	1.142438e-3
GO:0044281	small molecule metabolic process	1.144297e-3
GO:0051961	negative regulation of nervous system development	1.165715e-3
GO:0006183	GTP biosynthetic process	1.165715e-3
GO:0002697	regulation of immune effector process	1.173003e-3
GO:0051125	regulation of actin nucleation	1.226456e-3
GO:0014910	regulation of smooth muscle cell migration	1.231059e-3
GO:0060157	urinary bladder development	1.232766e-3
GO:0031099	regeneration	1.240202e-3
GO:0060737	prostate gland morphogenetic growth	1.261989e-3
GO:0002367	cytokine production involved in immune response	1.274478e-3
GO:0002155	regulation of thyroid hormone mediated signaling pathway	1.276296e-3
GO:0001570	vasculogenesis	1.285073e-3
GO:0042308	negative regulation of protein import into nucleus	1.289003e-3
GO:0070374	positive regulation of ERK1 and ERK2 cascade	1.302609e-3
GO:0001957	intramembranous ossification	1.313246e-3
GO:0060993	kidney morphogenesis	1.335087e-3
GO:0071363	cellular response to growth factor stimulus	1.335269e-3
GO:0042742	defense response to bacterium	1.336350e-3
GO:0071359	cellular response to dsRNA	1.342172e-3
GO:0042268	regulation of cytolysis	1.359281e-3
GO:0006996	organelle organization	1.364002e-3
GO:0002369	T cell cytokine production	1.365069e-3
GO:0042278	purine nucleoside metabolic process	1.414990e-3
GO:0031100	organ regeneration	1.458343e-3
GO:0060056	mammary gland involution	1.473692e-3
GO:0014912	negative regulation of smooth muscle cell migration	1.473692e-3
GO:0003382	epithelial cell morphogenesis	1.475891e-3
GO:0006241	CTP biosynthetic process	1.515703e-3
GO:0045925	positive regulation of female receptivity	1.546136e-3
GO:0042245	RNA repair	1.546136e-3
GO:0014719	satellite cell activation	1.546136e-3
GO:0035659	Wnt receptor signaling pathway involved in wound healing, spreading of epidermal cells	1.546136e-3
GO:0009218	pyrimidine ribonucleotide metabolic process	1.552488e-3
GO:0035674	tricarboxylic acid transmembrane transport	1.553063e-3
GO:0002023	reduction of food intake in response to dietary excess	1.553063e-3
GO:0030335	positive regulation of cell migration	1.563134e-3
GO:0071956	cellular component maintenance at cellular level	1.575171e-3
GO:0042473	outer ear morphogenesis	1.575171e-3
GO:0043367	CD4-positive, alpha-beta T cell differentiation	1.674975e-3
GO:0045722	positive regulation of gluconeogenesis	1.677809e-3
GO:0060022	hard palate development	1.702185e-3
GO:0060066	oviduct development	1.768594e-3
GO:0002376	immune system process	1.773380e-3
GO:0042376	phylloquinone catabolic process	1.773756e-3
GO:0070613	regulation of protein processing	1.799777e-3
GO:0042982	amyloid precursor protein metabolic process	1.811292e-3
GO:0009052	pentose-phosphate shunt, non-oxidative branch	1.816041e-3
GO:0060676	ureteric bud formation	1.816041e-3
GO:0040017	positive regulation of locomotion	1.873235e-3
GO:0051222	positive regulation of protein transport	1.908672e-3
GO:0050715	positive regulation of cytokine secretion	1.919331e-3
GO:0032729	positive regulation of interferon-gamma production	1.919427e-3
GO:0002839	positive regulation of immune response to tumor cell	1.919573e-3
GO:0046131	pyrimidine ribonucleoside metabolic process	1.960480e-3
GO:0002684	positive regulation of immune system process	1.981095e-3
GO:0040023	establishment of nucleus localization	2.009312e-3
GO:0006952	defense response	2.021421e-3
GO:0048070	regulation of developmental pigmentation	2.102455e-3
GO:0002837	regulation of immune response to tumor cell	2.102455e-3
GO:0014075	response to amine stimulus	2.109684e-3
GO:0010927	cellular component assembly involved in morphogenesis	2.168491e-3
GO:0035710	CD4-positive, alpha-beta T cell activation	2.193117e-3
GO:0045759	negative regulation of action potential	2.200126e-3
GO:0070208	protein heterotrimerization	2.223553e-3
GO:0010043	response to zinc ion	2.226634e-3
GO:0046496	nicotinamide nucleotide metabolic process	2.260637e-3
GO:0051238	sequestering of metal ion	2.261544e-3
GO:0006066	alcohol metabolic process	2.309942e-3
GO:0070536	protein K63-linked deubiquitination	2.315067e-3
GO:0051291	protein heterooligomerization	2.437248e-3
GO:0045087	innate immune response	2.462304e-3
GO:0032873	negative regulation of stress-activated MAPK cascade	2.463125e-3
GO:0030730	sequestering of triglyceride	2.542304e-3
GO:0050865	regulation of cell activation	2.551851e-3
GO:0001954	positive regulation of cell-matrix adhesion	2.557855e-3
GO:0031960	response to corticosteroid stimulus	2.568013e-3
GO:0002694	regulation of leukocyte activation	2.585374e-3
GO:0070318	positive regulation of G0 to G1 transition	2.589274e-3
GO:0060346	bone trabecula formation	2.622628e-3
GO:0002833	positive regulation of response to biotic stimulus	2.622628e-3
GO:0051726	regulation of cell cycle	2.634949e-3
GO:0043200	response to amino acid stimulus	2.637338e-3
GO:0060677	ureteric bud elongation	2.696564e-3
GO:0051289	protein homotetramerization	2.740818e-3
GO:0032273	positive regulation of protein polymerization	2.744421e-3
GO:0046587	positive regulation of calcium-dependent cell-cell adhesion	2.744593e-3
GO:0001824	blastocyst development	2.795932e-3
GO:0002286	T cell activation involved in immune response	2.833113e-3
GO:0070474	positive regulation of uterine smooth muscle contraction	2.847491e-3
GO:0033598	mammary gland epithelial cell proliferation	2.928935e-3
GO:0050867	positive regulation of cell activation	2.968479e-3
GO:0002528	regulation of vascular permeability involved in acute inflammatory response	3.023122e-3
GO:0055002	striated muscle cell development	3.155071e-3
GO:0030388	fructose 1,6-bisphosphate metabolic process	3.212666e-3
GO:0030155	regulation of cell adhesion	3.241048e-3
GO:0051894	positive regulation of focal adhesion assembly	3.298512e-3
GO:0060527	prostate epithelial cord arborization involved in prostate glandular acinus morphogenesis	3.420665e-3
GO:0060541	respiratory system development	3.421039e-3
GO:0007015	actin filament organization	3.431240e-3
GO:0031659	positive regulation of cyclin-dependent protein kinase activity involved in G1/S	3.487970e-3
GO:0060262	negative regulation of N-terminal protein palmitoylation	3.489679e-3
GO:0034474	U2 snRNA 3'-end processing	3.489679e-3
GO:0031104	dendrite regeneration	3.489679e-3
GO:0016119	carotene metabolic process	3.489679e-3
GO:0030643	cellular phosphate ion homeostasis	3.496694e-3
GO:0046333	octopamine metabolic process	3.503165e-3
GO:0042309	homoiothermy	3.503165e-3
GO:0032235	negative regulation of calcium ion transport via store-operated calcium channel activity	3.503165e-3
GO:0043526	neuroprotection	3.526768e-3
GO:0009148	pyrimidine nucleoside triphosphate biosynthetic process	3.539611e-3
GO:0014045	establishment of endothelial blood-brain barrier	3.539611e-3
GO:0032649	regulation of interferon-gamma production	3.615963e-3
GO:0033157	regulation of intracellular protein transport	3.706411e-3
GO:0040020	regulation of meiosis	3.720011e-3
GO:0042633	hair cycle	3.769257e-3
GO:0071219	cellular response to molecule of bacterial origin	3.769823e-3
GO:0002540	leukotriene production involved in inflammatory response	3.793878e-3
GO:0060442	branching involved in prostate gland morphogenesis	3.823361e-3
GO:0051050	positive regulation of transport	3.854182e-3
GO:0031333	negative regulation of protein complex assembly	3.889922e-3
GO:0048286	lung alveolus development	3.928531e-3
GO:0001658	branching involved in ureteric bud morphogenesis	3.929484e-3
GO:0043410	positive regulation of MAPKKK cascade	3.952036e-3
GO:0046823	negative regulation of nucleocytoplasmic transport	4.003611e-3
GO:0071338	positive regulation of hair follicle cell proliferation	4.034407e-3
GO:0045815	positive regulation of gene expression, epigenetic	4.170270e-3
GO:0030003	cellular cation homeostasis	4.260893e-3
GO:0002864	regulation of acute inflammatory response to antigenic stimulus	4.280694e-3
GO:0048878	chemical homeostasis	4.291879e-3
GO:0044087	regulation of cellular component biogenesis	4.317263e-3
GO:0032287	peripheral nervous system myelin maintenance	4.336079e-3
GO:0090275	negative regulation of somatostatin secretion	4.377697e-3
GO:0006043	glucosamine catabolic process	4.377697e-3
GO:0045933	positive regulation of muscle contraction	4.393821e-3
GO:0012501	programmed cell death	4.435669e-3
GO:0042364	water-soluble vitamin biosynthetic process	4.449188e-3
GO:0046822	regulation of nucleocytoplasmic transport	4.563814e-3
GO:0070316	regulation of G0 to G1 transition	4.616437e-3
GO:0046121	deoxyribonucleoside catabolic process	4.616437e-3
GO:0035136	forelimb morphogenesis	4.624901e-3
GO:0007185	transmembrane receptor protein tyrosine phosphatase signaling pathway	4.640218e-3
GO:0042522	regulation of tyrosine phosphorylation of Stat5 protein	4.694175e-3
GO:0006820	anion transport	4.933572e-3
GO:0001541	ovarian follicle development	4.981139e-3
GO:0030199	collagen fibril organization	5.168916e-3
GO:0001771	immunological synapse formation	5.204229e-3
GO:0060591	chondroblast differentiation	5.257477e-3
GO:0060281	regulation of oocyte development	5.257477e-3
GO:0060282	positive regulation of oocyte development	5.257477e-3
GO:0001798	positive regulation of type IIa hypersensitivity	5.278638e-3
GO:0051445	regulation of meiotic cell cycle	5.354980e-3
GO:0070094	positive regulation of glucagon secretion	5.372989e-3
GO:0006278	RNA-dependent DNA replication	5.422190e-3
GO:2000352	negative regulation of endothelial cell apoptosis	5.433328e-3
GO:0046483	heterocycle metabolic process	5.446923e-3
GO:0071222	cellular response to lipopolysaccharide	5.477461e-3
GO:0048664	neuron fate determination	5.608080e-3
GO:0071391	cellular response to estrogen stimulus	5.614862e-3
GO:0031579	membrane raft organization	5.621492e-3
GO:0046128	purine ribonucleoside metabolic process	5.624221e-3
GO:0051495	positive regulation of cytoskeleton organization	5.721030e-3
GO:0060580	ventral spinal cord interneuron fate determination	5.721513e-3
GO:0070434	positive regulation of nucleotide-binding oligomerization domain containing 2 signaling pathway	5.721513e-3
GO:0070430	positive regulation of nucleotide-binding oligomerization domain containing 1 signaling pathway	5.721513e-3
GO:0032707	negative regulation of interleukin-23 production	5.721513e-3
GO:0003327	type B pancreatic cell fate commitment	5.721513e-3
GO:0019896	axon transport of mitochondrion	5.721513e-3
GO:0045362	positive regulation of interleukin-1 biosynthetic process	5.721513e-3
GO:0022610	biological adhesion	5.975763e-3
GO:0046653	tetrahydrofolate metabolic process	5.980727e-3
GO:0031018	endocrine pancreas development	6.048318e-3
GO:0019693	ribose phosphate metabolic process	6.160015e-3
GO:0006873	cellular ion homeostasis	6.317548e-3
GO:0061138	morphogenesis of a branching epithelium	6.405750e-3
GO:0060405	regulation of penile erection	6.483690e-3
GO:0015937	coenzyme A biosynthetic process	6.483690e-3
GO:0021956	central nervous system interneuron axonogenesis	6.493269e-3
GO:0060525	prostate glandular acinus development	6.519305e-3
GO:0071418	cellular response to amine stimulus	6.566413e-3
GO:0001556	oocyte maturation	6.577792e-3
GO:0071230	cellular response to amino acid stimulus	6.691842e-3
GO:0038007	netrin-activated signaling pathway	6.694215e-3
GO:0002347	response to tumor cell	6.694215e-3
GO:0001560	regulation of cell growth by extracellular stimulus	6.694215e-3
GO:0060675	ureteric bud morphogenesis	6.862357e-3
GO:0030002	cellular anion homeostasis	6.890835e-3
GO:0044085	cellular component biogenesis	6.891737e-3
GO:0007623	circadian rhythm	6.930924e-3
GO:0031577	spindle checkpoint	6.956832e-3
GO:0022009	central nervous system vasculogenesis	6.956832e-3
GO:0001503	ossification	6.970153e-3
GO:0019370	leukotriene biosynthetic process	7.073548e-3
GO:0051130	positive regulation of cellular component organization	7.170954e-3
GO:0006878	cellular copper ion homeostasis	7.204607e-3
GO:0000302	response to reactive oxygen species	7.237254e-3
GO:0055081	anion homeostasis	7.257191e-3
GO:0030323	respiratory tube development	7.317588e-3
GO:0042698	ovulation cycle	7.330808e-3
GO:0046590	embryonic leg morphogenesis	7.500367e-3
GO:0048378	regulation of lateral mesodermal cell fate specification	7.504190e-3
GO:0010833	telomere maintenance via telomere lengthening	7.504190e-3
GO:0032696	negative regulation of interleukin-13 production	7.590820e-3
GO:0006220	pyrimidine nucleotide metabolic process	7.633831e-3
GO:0071422	succinate transmembrane transport	7.742223e-3
GO:0018101	peptidyl-citrulline biosynthetic process from peptidyl-arginine	7.742223e-3
GO:0060602	branch elongation of an epithelium	7.784479e-3
GO:0071417	cellular response to organic nitrogen	7.790765e-3
GO:0006766	vitamin metabolic process	7.793070e-3
GO:0001938	positive regulation of endothelial cell proliferation	7.944722e-3
GO:0002696	positive regulation of leukocyte activation	7.957565e-3
GO:0055082	cellular chemical homeostasis	7.972083e-3
GO:0009725	response to hormone stimulus	8.118583e-3
GO:0048861	leukemia inhibitory factor signaling pathway	8.150916e-3
GO:0022607	cellular component assembly	8.154967e-3
GO:0050896	response to stimulus	8.202682e-3
GO:0010243	response to organic nitrogen	8.302703e-3
GO:0051160	L-xylitol catabolic process	8.442942e-3
GO:0071284	cellular response to lead ion	8.442942e-3
GO:0046370	fructose biosynthetic process	8.442942e-3