FF:12641-134G4: Difference between revisions
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{{f5samples | {{f5samples | ||
| | |DRA_sample_Accession=CAGE@SAMD00005797 | ||
| | |accession_numbers=CAGE;DRX008594;DRR009466;DRZ000891;DRZ002276;DRZ012241;DRZ013626 | ||
|ancestors_in_anatomy_facet= | |ancestors_in_anatomy_facet= | ||
|ancestors_in_cell_lineage_facet=CL:0000000,CL:0000003,CL:0000548,CL:0000075,CL:0000066,CL:0002371,CL:0000325,CL:0000147,CL:0000710,CL:0000255,CL:0002077,CL:0000148 | |||
|ancestors_in_disease_facet= | |ancestors_in_disease_facet= | ||
| | |ancestors_in_ff_facet=FF:0000210,FF:0000101,FF:0000001,FF:0000343,FF:0000350,FF:0000730 | ||
|comment= | |||
|created_by= | |||
|creation_date= | |||
|data_phase=2 | |||
|datafreeze_phase=2 | |||
|def= | |||
|expression_enrichment_score=chr22:38380543..38380569,-!p1@SOX10!2.57!372.03!SOX10;;chr3:69985734..69985749,+!p2@MITF!2.32!209.67!MITF;;chr19:3574330..3574393,+!p2@HMG20B!2.16!144.68!HMG20B;;chr6:10412600..10412637,-!p1@TFAP2A!1.98!154.24!TFAP2A;;chr19:3574157..3574180,+!p4@HMG20B!1.92!82.16!HMG20B;;chr6:391743..391759,+!p1@IRF4!1.89!76.71!IRF4;;chr2:223163706..223163730,-!p1@PAX3!1.89!76.30!PAX3;;chr6:10415276..10415341,-!p2@TFAP2A!1.87!89.15!TFAP2A;;chr2:239148671..239148686,-!p1@HES6!1.61!138.92!HES6;;chr6:10415484..10415508,-!p3@TFAP2A!1.60!38.97!TFAP2A;;chr15:42749722..42749739,-!p2@ZFP106!1.59!66.94!ZFP106;;chr19:3574400..3574430,+!p6@HMG20B!1.59!38.05!HMG20B;;chr6:10412576..10412599,-!p5@TFAP2A!1.41!24.47!TFAP2A;;chr17:59477233..59477263,+!p1@TBX2!1.40!72.39!TBX2;;chr16:67198683..67198698,+!p2@HSF4!1.38!23.03!HSF4;;chr11:125034640..125034655,+!p1@PKNOX2!1.30!19.13!PKNOX2;;chr16:67198633..67198671,+!p1@HSF4!1.30!19.02!HSF4;;chr1:25256756..25256774,-!p1@RUNX3!1.19!27.15!RUNX3;;chr8:72756637..72756664,-!p3@MSC!1.17!15.84!MSC;;chr3:69985792..69985803,+!p7@MITF!1.16!13.37!MITF;;chr7:44143925..44143970,+!p1@AEBP1!1.13!277.43!AEBP1;;chr17:59477275..59477286,+!p3@TBX2!1.13!16.45!TBX2;;chr7:44143978..44143989,+!p2@AEBP1!1.09!20.87!AEBP1;;chr1:158985493..158985535,+!p4@IFI16!1.08!16.86!IFI16;;chr20:32274179..32274213,-!p1@E2F1!1.06!70.85!E2F1;;chr1:63788229..63788250,+!p1@FOXD3!1.06!10.39!FOXD3;;chr5:321810..321877,+!p1@AHRR!1.05!32.60!AHRR;;chr9:102584262..102584276,+!p1@NR4A3!1.05!22.83!NR4A3;;chr9:102584159..102584174,+!p2@NR4A3!1.05!18.61!NR4A3;;chr2:145277882..145277967,-!p3@ZEB2!1.03!16.76!ZEB2;;chr17:59477197..59477212,+!p2@TBX2!1.02!16.35!TBX2;;chrY:21906594..21906622,-!p1@KDM5D!1.02!9.56!KDM5D;;chr9:99180617..99180658,-!p1@ZNF367!1.01!20.57!ZNF367;;chr12:54410664..54410684,+!p1@HOXC4,p1@HOXC5,p1@HOXC6!1.01!9.15!HOXC5;;chr20:55204351..55204377,+!p1@TFAP2C!0.98!11.11!TFAP2C;;chr7:44143997..44144008,+!p3@AEBP1!0.98!11.00!AEBP1;;chr6:1389789..1389821,+!p1@FOXF2!0.94!10.69!FOXF2;;chr19:3572925..3573014,+!p1@HMG20B!0.93!230.03!HMG20B;;chr11:65667884..65667895,-!p2@FOSL1!0.93!30.23!FOSL1;;chr10:111987079..111987115,+!p3@MXI1!0.93!10.39!MXI1;;chr17:46688334..46688385,-!p1@HOXB7!0.92!10.69!HOXB7;;chr8:145669791..145669834,-!p1@TONSL!0.91!21.39!TONSL;;chr4:109089095..109089144,-!p6@LEF1!0.91!7.10!LEF1;;chr9:102584128..102584144,+!p3@NR4A3!0.89!13.26!NR4A3;;chr12:85673977..85674015,+!p1@ALX1!0.88!6.58!ALX1;;chr11:125034605..125034636,+!p2@PKNOX2!0.87!6.38!PKNOX2;;chr8:72756667..72756736,-!p2@MSC!0.85!9.77!MSC;;chr6:10415263..10415274,-!p8@TFAP2A!0.85!6.07!TFAP2A;;chr2:96012397..96012417,+!p3@KCNIP3!0.84!5.86!KCNIP3;;chr15:57511609..57511651,+!p2@TCF12!0.82!9.77!TCF12;;chr19:3572689..3572697,+!p22@HMG20B!0.82!5.55!HMG20B;;chr20:32274150..32274166,-!p2@E2F1!0.79!10.08!E2F1;;chr19:3572758..3572795,+!p7@HMG20B!0.78!5.04!HMG20B;;chr12:54447637..54447659,+!p4@HOXC4!0.78!5.04!HOXC4;;chr2:5832508..5832524,+!p1@SOX11!0.78!5.04!SOX11;;chr8:49833978..49833996,-!p1@SNAI2!0.77!111.26!SNAI2;;chr2:96012757..96012779,+!p8@KCNIP3!0.77!4.94!KCNIP3;;chr12:54393880..54393962,+!p1@HOXC9!0.77!4.94!HOXC9;;chr19:3574468..3574478,+!p19@HMG20B!0.77!4.83!HMG20B;;chr8:128748308..128748324,+!p2@MYC!0.76!146.22!MYC;;chr12:52445218..52445237,+!p1@NR4A1!0.75!65.30!NR4A1;;chr1:23857698..23857733,-!p1@E2F2!0.75!9.05!E2F2;;chr12:54447599..54447630,+!p3@HOXC4!0.75!5.86!HOXC4;;chr17:46687959..46688007,-!p2@HOXB7!0.74!6.48!HOXB7;;chr9:16728327..16728338,-!p5@BNC2!0.74!4.52!BNC2;;chr12:54394416..54394467,+!p5@HOXC9!0.73!4.32!HOXC9;;chr8:72756267..72756296,-!p4@MSC!0.72!6.58!MSC;;chr12:52431016..52431071,+!p4@NR4A1!0.72!5.04!NR4A1;;chr4:109088940..109089037,-!p4@LEF1!0.72!4.22!LEF1;;chr11:65667846..65667868,-!p1@FOSL1!0.71!124.94!FOSL1;;chr6:10412392..10412409,-!p4@TFAP2A!0.71!4.83!TFAP2A;;chr12:85674018..85674039,+!p3@ALX1!0.71!4.11!ALX1;;chrY:2803415..2803468,+!p1@ZFY!0.71!4.11!ZFY;;chr2:145277640..145277771,-!p1@ZEB2!0.70!61.49!ZEB2;;chr12:52430894..52430952,+!p3@NR4A1!0.70!8.33!NR4A1;;chr19:3576938..3576962,+!p9@HMG20B!0.69!3.91!HMG20B;;chr17:41623692..41623715,-!p1@ETV4!0.68!18.41!ETV4;;chr19:57946684..57946723,+!p1@ZNF749!0.67!47.09!ZNF749;;chr6:31126291..31126399,+!p1@TCF19!0.66!39.79!TCF19;;chr7:14029283..14029311,-!p1@ETV1!0.66!21.90!ETV1;;chr11:128392273..128392308,-!p2@ETS1!0.66!17.07!ETS1;;chr12:26277817..26277863,-!p2@BHLHE41!0.66!5.14!BHLHE41;;chr17:46682321..46682362,-!p1@HOXB6!0.66!3.60!HOXB6;;chr16:54320675..54320715,-!p1@IRX3!0.65!8.23!IRX3;;chr8:49833948..49833973,-!p2@SNAI2!0.64!25.09!SNAI2;;chr12:26277956..26277980,-!p1@BHLHE41!0.64!13.98!BHLHE41;;chr16:29819122..29819141,+!p34@MAZ!0.64!3.39!MAZ;;chr5:88178983..88179012,-!p1@MEF2C!0.63!29.92!MEF2C;;chr5:124082322..124082364,-!p1@ZNF608!0.63!9.46!ZNF608;;chr19:57352087..57352102,-!p1@PEG3,p1@ZIM2!0.63!3.29!PEG3;;chr1:120190786..120190915,-!p1@ZNF697!0.62!27.15!ZNF697;;chr10:35484053..35484076,+!p1@CREM!0.62!8.95!CREM;;chr12:54394309..54394336,+!p2@HOXC9!0.62!3.19!HOXC9;;chr1:158985553..158985574,+!p14@IFI16!0.62!3.19!IFI16;;chr6:10412477..10412490,-!p10@TFAP2A!0.62!3.19!TFAP2A;;chr1:935398..935465,-!p2@HES4!0.61!7.10!HES4;;chr9:99180662..99180690,-!p2@ZNF367!0.61!4.63!ZNF367;;chr2:176994408..176994492,+!p1@HOXD8!0.61!3.08!HOXD8;;chr18:3449720..3449749,+!p2@TGIF1!0.60!7.10!TGIF1;;chr9:99180597..99180614,-!p3@ZNF367!0.60!3.50!ZNF367;;chr12:26277929..26277955,-!p3@BHLHE41!0.59!4.42!BHLHE41;;chr11:16627528..16627550,-!p7@SOX6!0.59!2.88!SOX6;;chr12:54410639..54410659,+!p2@HOXC4,p2@HOXC5,p2@HOXC6!0.59!2.88!HOXC5;;chr13:41635759..41635774,-!p21@ELF1!0.59!2.88!ELF1;;chr2:96012353..96012378,+!p4@KCNIP3!0.59!2.88!KCNIP3;;chr11:65686732..65686756,+!p2@DRAP1!0.58!14.29!DRAP1;;chr19:22817119..22817145,+!p1@ZNF492!0.58!5.14!ZNF492;;chr20:50179368..50179392,-!p2@NFATC2!0.58!3.80!NFATC2;;chr4:109089901..109089930,-!p3@LEF1!0.58!2.78!LEF1;;chr6:10415645..10415675,-!p19@TFAP2A!0.58!2.78!TFAP2A;;chr1:204042233..204042249,+!p1@SOX13!0.57!20.87!SOX13;;chr6:19837592..19837621,+!p1@ID4!0.57!20.46!ID4;;chr8:22550982..22550999,-!p1@EGR3!0.57!9.05!EGR3;;chr3:185826286..185826318,-!p5@ETV5!0.57!3.19!ETV5;;chr1:25256439..25256476,-!p3@RUNX3!0.57!2.67!RUNX3;;chr16:29819403..29819442,+!p5@MAZ!0.56!27.04!MAZ;;chr12:3068544..3068597,+!p1@TEAD4!0.56!19.43!TEAD4;;chr17:41277372..41277418,-!p1@BRCA1!0.56!11.62!BRCA1;;chr3:126076264..126076305,-!p2@KLF15!0.56!4.01!KLF15;;chr9:102584241..102584261,+!p4@NR4A3!0.55!4.32!NR4A3;;chr3:32023232..32023273,+!p1@ZNF860!0.55!3.91!ZNF860;;chr20:61493117..61493187,-!p1@TCFL5!0.54!35.99!TCFL5;;chr6:20402102..20402152,+!p1@E2F3!0.54!12.34!E2F3;;chr12:2986275..2986363,-!p1@FOXM1!0.53!30.23!FOXM1;;chr14:55493763..55493824,-!p1@WDHD1!0.53!22.72!WDHD1;;chr16:29819446..29819471,+!p9@MAZ!0.53!8.53!MAZ;;chr2:71127699..71127744,+!p1@VAX2!0.53!5.76!VAX2;;chr16:54964740..54964789,+!p1@IRX5!0.53!3.80!IRX5;;chr12:24715376..24715432,-!p1@SOX5!0.53!3.19!SOX5;;chr12:54422217..54422239,+!p3@HOXC6!0.53!2.37!HOXC6;;chr15:57511589..57511608,+!p4@TCF12!0.53!2.37!TCF12;;chr3:185826855..185826911,-!p1@ETV5!0.52!82.88!ETV5;;chr19:58341656..58341694,+!p5@ZNF587!0.51!2.88!ZNF587;;chr20:42295713..42295738,+!p2@MYBL2!0.50!16.56!MYBL2;;chrY:21906761..21906810,-!p2@KDM5D!0.50!2.16!KDM5D;;chr11:125034586..125034604,+!p3@PKNOX2!0.50!2.16!PKNOX2;;chr1:158979792..158979814,+!p2@IFI16!0.49!26.53!IFI16;;chr9:16870659..16870675,-!p2@BNC2!0.49!2.78!BNC2;;chr4:109090106..109090124,-!p10@LEF1!0.49!2.06!LEF1;;chr16:79634624..79634642,-!p1@MAF!0.48!10.18!MAF;;chr3:126076242..126076257,-!p1@KLF15!0.48!2.67!KLF15;;chr19:1592714..1592762,-!p1@MBD3!0.47!19.64!MBD3;;chr9:99180739..99180752,-!p4@ZNF367!0.47!1.95!ZNF367;;chr2:145277833..145277845,-!p16@ZEB2!0.47!1.95!ZEB2;;chr19:35759824..35759891,+!p1@USF2!0.46!80.72!USF2;;chr3:25469724..25469773,+!p1@RARB!0.46!3.08!RARB;;chr6:34204921..34204939,+!p3@HMGA1!0.45!76.81!HMGA1;;chr8:67525473..67525518,-!p1@MYBL1!0.45!5.14!MYBL1;;chr5:139487608..139487663,+!p3@PURA!0.45!4.83!PURA;;chr16:67197654..67197716,+!p3@HSF4!0.45!1.85!HSF4;;chr17:46806067..46806097,-!p1@HOXB13!0.45!1.85!HOXB13;;chr9:132427883..132427951,+!p2@PRRX2!0.45!1.85!PRRX2;;chr9:16728161..16728185,-!p4@BNC2!0.45!1.85!BNC2;;chr13:41635029..41635044,-!p4@ELF1!0.44!4.63!ELF1;;chr17:46622440..46622477,-!p5@HOXB2!0.44!2.06!HOXB2;;chr7:27190547..27190591,-!p1@HOXA6!0.44!1.75!HOXA6;;chr8:49834430..49834446,-!p5@SNAI2!0.44!1.75!SNAI2;;chr2:145277792..145277808,-!p15@ZEB2!0.44!1.75!ZEB2;;chr3:69986115..69986119,+!p12@MITF!0.44!1.75!MITF;;chr11:695006..695074,-!p1@DEAF1!0.43!37.74!DEAF1;;chr1:47779762..47779827,-!p1@STIL,p1@TAL1!0.43!10.49!TAL1;;chr5:88179017..88179046,-!p2@MEF2C!0.43!9.15!MEF2C;;chr7:150945754..150945789,-!p2@SMARCD3!0.43!6.89!SMARCD3;;chr19:46271505..46271575,-!p2@SIX5!0.43!5.55!SIX5;;chr17:46655730..46655791,-!p1@HOXB4!0.43!5.45!HOXB4;;chr13:46543725..46543747,-!p2@ZC3H13!0.43!3.91!ZC3H13;;chr1:170632285..170632309,+!p1@PRRX1!0.43!2.06!PRRX1;;chr11:128392085..128392232,-!p1@ETS1!0.42!80.00!ETS1;;chr1:158979686..158979745,+!p1@IFI16!0.42!78.97!IFI16;;chr3:69788576..69788648,+!p1@MITF!0.42!12.13!MITF;;chr12:7079780..7079791,-!p2@PHB2!0.42!12.03!PHB2;;chr1:45805872..45805900,+!p2@TOE1!0.42!5.04!TOE1;;chr15:42743341..42743377,-!p3@ZFP106!0.42!3.29!ZFP106;;chr15:96875657..96875760,+!p14@NR2F2!0.42!3.19!NR2F2;;chr22:42269885..42269899,+!p4@SREBF2!0.42!2.88!SREBF2;;chr5:124082279..124082319,-!p3@ZNF608!0.42!2.16!ZNF608;;chr5:3595977..3595999,+!p1@IRX1!0.42!1.65!IRX1;;chr6:10412338..10412345,-!p17@TFAP2A!0.42!1.65!TFAP2A;;chr7:27205136..27205164,-!p1@HOXA9!0.42!1.65!HOXA9;;chr11:65480222..65480241,+!p4@KAT5!0.42!1.65!KAT5;;chr19:17356697..17356762,-!p1@NR2F6!0.41!31.67!NR2F6;;chr1:249153268..249153298,-!p1@ZNF692!0.41!11.83!ZNF692;;chr1:45805813..45805859,+!p1@TOE1!0.41!10.08!TOE1;;chr8:102217679..102217719,-!p2@ZNF706!0.41!7.40!ZNF706;;chr17:20492136..20492165,+!p1@MEIS3P2!0.41!2.98!MEIS3P2;;chr18:3449695..3449712,+!p9@TGIF1!0.41!2.88!TGIF1;;chr16:1031762..1031781,+!p1@SOX8!0.41!1.54!SOX8;;chr17:59477266..59477273,+!p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| |||
|fantom_cat=http://fantom.gsc.riken.jp/5/suppl/Hon_et_al_2016/vis/#/ontologies/CL:0000066;;http://fantom.gsc.riken.jp/5/suppl/Hon_et_al_2016/vis/#/ontologies/CL:0000133;;http://fantom.gsc.riken.jp/5/suppl/Hon_et_al_2016/vis/#/ontologies/CL:0000147;;http://fantom.gsc.riken.jp/5/suppl/Hon_et_al_2016/vis/#/ontologies/CL:0000148;;http://fantom.gsc.riken.jp/5/suppl/Hon_et_al_2016/vis/#/ontologies/CL:0000221;;http://fantom.gsc.riken.jp/5/suppl/Hon_et_al_2016/vis/#/ontologies/CL:0000710;;http://fantom.gsc.riken.jp/5/suppl/Hon_et_al_2016/vis/#/ontologies/CL:0002077 | |||
|ffid_belonging_in_development=CL:0000133,CL:0000221 | |||
|fonse_cell_line= | |fonse_cell_line= | ||
|fonse_cell_line_closure= | |fonse_cell_line_closure= | ||
Line 66: | Line 41: | ||
|fonse_treatment=FF:0000343,FF:0000730,FF:12641-134G4 | |fonse_treatment=FF:0000343,FF:0000730,FF:12641-134G4 | ||
|fonse_treatment_closure=FF:0000343,FF:0000730,FF:12641-134G4 | |fonse_treatment_closure=FF:0000343,FF:0000730,FF:12641-134G4 | ||
|top_motifs= | |has_quality= | ||
|hg19bam=http://fantom.gsc.riken.jp/5/datafiles/latest/basic/human.timecourse.hCAGE/Melanocyte%252c%2520donor1%2520%2528MC%252b1%2529.CNhs12816.12641-134G4.hg19.nobarcode.bam | |||
|hg19ctss=http://fantom.gsc.riken.jp/5/datafiles/latest/basic/human.timecourse.hCAGE/Melanocyte%252c%2520donor1%2520%2528MC%252b1%2529.CNhs12816.12641-134G4.hg19.ctss.bed.gz | |||
|hg19fasta=http://fantom.gsc.riken.jp/5/datafiles/latest/basic/human.timecourse.hCAGE/Melanocyte%252c%2520donor1%2520%2528MC%252b1%2529.CNhs12816.12641-134G4.hg19.nobarcode.rdna.fa.gz | |||
|hg38bam=http://fantom.gsc.riken.jp/5/datafiles/reprocessed/hg38_v2/basic/human.timecourse.hCAGE/Melanocyte%252c%2520donor1%2520%2528MC%252b1%2529.CNhs12816.12641-134G4.hg38.nobarcode.bam | |||
|hg38ctss=http://fantom.gsc.riken.jp/5/datafiles/reprocessed/hg38_v2/basic/human.timecourse.hCAGE/Melanocyte%252c%2520donor1%2520%2528MC%252b1%2529.CNhs12816.12641-134G4.hg38.nobarcode.ctss.bed.gz | |||
|id=FF:12641-134G4 | |||
|is_a=EFO:0002091;;FF:0000730 | |||
|is_obsolete= | |||
|library_id=CNhs12816 | |||
|library_id_phase_based=2:CNhs12816 | |||
|microRNAs= | |||
|microRNAs_nn= | |||
|microRNAs_nonnovel_cage=http://fantom.gsc.riken.jp/5/suppl/De_Rie_et_al_2017/vis_viewer/#/human#cage;sample;12641 | |||
|microRNAs_novel_cage=http://fantom.gsc.riken.jp/5/suppl/De_Rie_et_al_2017/vis_viewer_novel/#/human#cage;sample;12641 | |||
|name=Melanocyte, donor1 (MC+1) | |||
|namespace=FANTOM5 | |||
|part_of= | |||
|profile_cagescan=,,, | |||
|profile_hcage=CNhs12816,LSID972,release012,COMPLETED | |||
|profile_rnaseq= | |||
|profile_srnaseq=,,, | |||
|refex=http://refex.dbcls.jp/genelist.php?lang | |||
|repeat_enrich_byfamily=0,0,0,0,0,0,0,-0.079094983784001,0,-0.277362132193514,-0.118101399479212,0,0,0,0,0,0,0,0,0,0,0,0.0812230463023852,0,0.317046660520985,0,0,0,0,0,-0.0554503120474897,0,0,0.0166658200274416,0,0,0,0,0,0,0,0,0,0,0,0,-0.0817726721095548,0,0,0,0,0,0,0,0,-0.00296122900255046,0,0,0,0.0425075842205678,0,0.00871456963900237,0,0.0526300485636987,0,0,-0.0548360429925292,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,-0.042456930013169,0.0212537921102839,0,0,0,0,0,0.0462014060683268,0,0,0,0.124041730485214,-0.0366626310003659,0,0,0,0,-0.0980353512377064,-0.080093245112373,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,-0.0557620707712685,0.0812230463023852,0,0,-0.0768003193605724,-0.253234448611991,0,0,0,0,0,0 | |||
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| |||
|rna_box=134 | |||
|rna_catalog_number= | |||
|rna_concentration=0.84 | |||
|rna_extraction_protocol= | |||
|rna_lot_number= | |||
|rna_od260/230= | |||
|rna_od260/280= | |||
|rna_position=G4 | |||
|rna_rin= | |||
|rna_sample_type= | |||
|rna_tube_id=134G4 | |||
|rna_weight_ug=7 | |||
|sample_age= | |||
|sample_category=time courses | |||
|sample_cell_catalog= | |||
|sample_cell_line= | |||
|sample_cell_lot= | |||
|sample_cell_type=melanocyte | |||
|sample_collaboration=Susan Zabierowski (Wistar Institute) | |||
|sample_company= | |||
|sample_description= | |||
|sample_dev_stage= | |||
|sample_disease= | |||
|sample_donor(cell lot)=rep1 | |||
|sample_ethnicity= | |||
|sample_experimental_condition=Human ES cell differentiation to melanocyte | |||
|sample_gostat=GO:0044464;cell part;0!GO:0005622;intracellular;0!GO:0044424;intracellular part;1.27964153963952e-264!GO:0043231;intracellular membrane-bound organelle;1.23766933857932e-224!GO:0043227;membrane-bound organelle;1.42797339480612e-224!GO:0043226;organelle;3.04337555956e-219!GO:0043229;intracellular organelle;7.78612443813852e-219!GO:0005737;cytoplasm;2.11931865600691e-204!GO:0044422;organelle part;1.88058375977293e-164!GO:0044446;intracellular organelle part;7.44126041333819e-163!GO:0044444;cytoplasmic part;1.47692604170209e-154!GO:0032991;macromolecular complex;5.37671167247125e-105!GO:0044237;cellular metabolic process;1.85823274065301e-98!GO:0044238;primary metabolic process;4.30216654366012e-97!GO:0030529;ribonucleoprotein complex;2.24211380331382e-92!GO:0043170;macromolecule metabolic process;2.77170430037233e-86!GO:0005634;nucleus;7.07716012685942e-84!GO:0044428;nuclear part;7.62263776522381e-79!GO:0005739;mitochondrion;2.89817430588423e-78!GO:0043233;organelle lumen;4.93282203117257e-78!GO:0031974;membrane-enclosed lumen;4.93282203117257e-78!GO:0003723;RNA binding;5.09644004379551e-71!GO:0005515;protein binding;3.25075170255374e-68!GO:0031090;organelle membrane;9.82892408503373e-63!GO:0005840;ribosome;1.91179067023629e-55!GO:0006396;RNA processing;1.79347698257856e-53!GO:0044429;mitochondrial part;1.16462837891508e-52!GO:0043234;protein complex;2.58823082884926e-52!GO:0006412;translation;4.24210883395943e-51!GO:0043283;biopolymer metabolic process;1.58928009736932e-50!GO:0016043;cellular component organization and biogenesis;1.77069566296101e-49!GO:0009058;biosynthetic process;7.72665116034735e-49!GO:0031967;organelle envelope;1.98983403706879e-48!GO:0031975;envelope;5.67924607073958e-48!GO:0003735;structural constituent of ribosome;7.9171472447001e-48!GO:0033036;macromolecule localization;2.09790038182654e-47!GO:0015031;protein transport;2.69572915624145e-47!GO:0019538;protein metabolic process;1.16499634936919e-45!GO:0031981;nuclear lumen;7.39244361040585e-45!GO:0008104;protein localization;6.07942792322133e-44!GO:0006139;nucleobase, nucleoside, nucleotide and nucleic acid metabolic process;6.28429101926254e-44!GO:0045184;establishment of protein localization;2.69516280993197e-43!GO:0044249;cellular biosynthetic process;2.76285228543149e-43!GO:0009059;macromolecule biosynthetic process;7.09729407550851e-43!GO:0033279;ribosomal subunit;2.76461740505144e-41!GO:0044260;cellular macromolecule metabolic process;3.45149879601842e-41!GO:0044267;cellular protein metabolic process;1.55554910509641e-40!GO:0010467;gene expression;4.91676884482545e-40!GO:0006259;DNA metabolic process;8.45508754790642e-39!GO:0006996;organelle organization and biogenesis;9.25565785052239e-39!GO:0016071;mRNA metabolic process;4.15244497126685e-38!GO:0005829;cytosol;4.16091651386862e-38!GO:0008380;RNA splicing;4.23933552967037e-37!GO:0046907;intracellular transport;1.48517401476767e-36!GO:0048770;pigment granule;1.49703485477075e-35!GO:0042470;melanosome;1.49703485477075e-35!GO:0022613;ribonucleoprotein complex biogenesis and assembly;1.84718031720709e-35!GO:0043228;non-membrane-bound organelle;6.21163362567689e-35!GO:0043232;intracellular non-membrane-bound organelle;6.21163362567689e-35!GO:0005740;mitochondrial envelope;1.49191522872357e-34!GO:0006397;mRNA processing;2.25672922051555e-33!GO:0065003;macromolecular complex assembly;2.89864748022404e-33!GO:0031966;mitochondrial membrane;3.72357417004986e-32!GO:0019866;organelle inner membrane;1.18504016547772e-31!GO:0006886;intracellular protein transport;2.02646578286512e-31!GO:0022607;cellular component assembly;1.30150079212995e-29!GO:0005743;mitochondrial inner membrane;3.80700840032365e-29!GO:0005830;cytosolic ribosome (sensu Eukaryota);4.99973020684468e-29!GO:0007049;cell cycle;2.67419073532317e-28!GO:0012505;endomembrane system;4.43383335554943e-27!GO:0005681;spliceosome;2.43219642781765e-26!GO:0005654;nucleoplasm;7.31263385575412e-26!GO:0003676;nucleic acid binding;1.39618778424227e-25!GO:0016462;pyrophosphatase activity;2.10103891961109e-25!GO:0000166;nucleotide binding;2.75791902906619e-25!GO:0016818;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides;2.91521400771136e-25!GO:0016817;hydrolase activity, acting on acid anhydrides;4.10472314520879e-25!GO:0006119;oxidative phosphorylation;1.97867372267227e-24!GO:0017111;nucleoside-triphosphatase activity;3.11014138633987e-24!GO:0044445;cytosolic part;3.71610684776785e-24!GO:0051649;establishment of cellular localization;4.17790560266368e-24!GO:0051641;cellular localization;4.52080009192171e-24!GO:0006974;response to DNA damage stimulus;3.85752220180156e-22!GO:0031980;mitochondrial lumen;6.52213814981803e-22!GO:0005759;mitochondrial matrix;6.52213814981803e-22!GO:0044455;mitochondrial membrane part;1.63204033477475e-21!GO:0005783;endoplasmic reticulum;1.69397854050178e-21!GO:0022402;cell cycle process;1.75516322385255e-21!GO:0015935;small ribosomal subunit;3.39594249882013e-21!GO:0015934;large ribosomal subunit;3.39594249882013e-21!GO:0005694;chromosome;9.9110287476223e-21!GO:0006457;protein folding;1.06673979091983e-20!GO:0044451;nucleoplasm part;1.82818733747079e-20!GO:0005730;nucleolus;5.32258240387711e-20!GO:0000278;mitotic cell cycle;1.01356591231183e-19!GO:0006281;DNA repair;2.24111067903386e-19!GO:0044427;chromosomal part;3.53123237869661e-19!GO:0022618;protein-RNA complex assembly;6.51349506576477e-19!GO:0032553;ribonucleotide binding;8.7606639056864e-19!GO:0032555;purine ribonucleotide binding;8.7606639056864e-19!GO:0017076;purine nucleotide binding;3.36657952502371e-18!GO:0016874;ligase activity;4.00503599177819e-18!GO:0006260;DNA replication;4.97066136321567e-18!GO:0005746;mitochondrial respiratory chain;5.81432072691481e-18!GO:0051186;cofactor metabolic process;7.76154661489719e-18!GO:0044432;endoplasmic reticulum part;1.20512676072009e-17!GO:0042254;ribosome biogenesis and assembly;2.31855533945786e-17!GO:0016070;RNA metabolic process;3.57454625422781e-17!GO:0016655;oxidoreductase activity, acting on NADH or NADPH, quinone or similar compound as acceptor;4.18242457522615e-17!GO:0022403;cell cycle phase;1.06845216236833e-16!GO:0005761;mitochondrial ribosome;1.25530211151837e-16!GO:0000313;organellar ribosome;1.25530211151837e-16!GO:0043285;biopolymer catabolic process;2.18184967319549e-16!GO:0005524;ATP binding;2.8670197590141e-16!GO:0006512;ubiquitin cycle;3.2177739263769e-16!GO:0005794;Golgi apparatus;3.51591536845389e-16!GO:0050136;NADH dehydrogenase (quinone) activity;3.6645946867263e-16!GO:0003954;NADH dehydrogenase activity;3.6645946867263e-16!GO:0008137;NADH dehydrogenase (ubiquinone) activity;3.6645946867263e-16!GO:0044265;cellular macromolecule catabolic process;3.86855410907111e-16!GO:0051082;unfolded protein binding;5.79101681755985e-16!GO:0032559;adenyl ribonucleotide binding;9.12197445778494e-16!GO:0009057;macromolecule catabolic process;1.2312816417019e-15!GO:0051276;chromosome organization and biogenesis;1.23520968380853e-15!GO:0000502;proteasome complex (sensu Eukaryota);1.26158881010654e-15!GO:0006605;protein targeting;1.90714651586598e-15!GO:0051301;cell division;3.86105667169748e-15!GO:0009719;response to endogenous stimulus;4.29160052783122e-15!GO:0008135;translation factor activity, nucleic acid binding;4.7301383125401e-15!GO:0005843;cytosolic small ribosomal subunit (sensu Eukaryota);5.25871107889587e-15!GO:0030554;adenyl nucleotide binding;5.25871107889587e-15!GO:0051603;proteolysis involved in cellular protein catabolic process;5.37456771386851e-15!GO:0006511;ubiquitin-dependent protein catabolic process;6.21934055472245e-15!GO:0044248;cellular catabolic process;8.12681080172303e-15!GO:0019941;modification-dependent protein catabolic process;8.43890933679479e-15!GO:0043632;modification-dependent macromolecule catabolic process;8.43890933679479e-15!GO:0005635;nuclear envelope;1.18982722285724e-14!GO:0044257;cellular protein catabolic process;1.30351709573258e-14!GO:0042623;ATPase activity, coupled;1.44311138044482e-14!GO:0000087;M phase of mitotic cell cycle;1.51536227370565e-14!GO:0016887;ATPase activity;1.61361537022151e-14!GO:0008134;transcription factor binding;1.70932525422893e-14!GO:0030163;protein catabolic process;1.73977029875512e-14!GO:0005842;cytosolic large ribosomal subunit (sensu Eukaryota);1.79868428318188e-14!GO:0016651;oxidoreductase activity, acting on NADH or NADPH;2.17626653900066e-14!GO:0030964;NADH dehydrogenase complex (quinone);2.46139930169261e-14!GO:0045271;respiratory chain complex I;2.46139930169261e-14!GO:0005747;mitochondrial respiratory chain complex I;2.46139930169261e-14!GO:0007067;mitosis;2.74661092706949e-14!GO:0042775;organelle ATP synthesis coupled electron transport;2.83494751348429e-14!GO:0042773;ATP synthesis coupled electron transport;2.83494751348429e-14!GO:0000398;nuclear mRNA splicing, via spliceosome;5.08123518971961e-14!GO:0000375;RNA splicing, via transesterification reactions;5.08123518971961e-14!GO:0000377;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile;5.08123518971961e-14!GO:0006732;coenzyme metabolic process;6.87270459950469e-14!GO:0006120;mitochondrial electron transport, NADH to ubiquinone;7.55302257531495e-14!GO:0031965;nuclear membrane;8.62223997259358e-14!GO:0000279;M phase;1.23193909186168e-13!GO:0044453;nuclear membrane part;1.80970186047299e-13!GO:0042175;nuclear envelope-endoplasmic reticulum network;3.71945367634445e-13!GO:0006399;tRNA metabolic process;3.99100048974252e-13!GO:0043412;biopolymer modification;6.42622892191633e-13!GO:0005789;endoplasmic reticulum membrane;6.77566647109341e-13!GO:0009259;ribonucleotide metabolic process;2.84157816252599e-12!GO:0006325;establishment and/or maintenance of chromatin architecture;3.15263331851048e-12!GO:0006364;rRNA processing;4.09111475145634e-12!GO:0048193;Golgi vesicle transport;4.85725645888679e-12!GO:0006163;purine nucleotide metabolic process;5.7948211862105e-12!GO:0006413;translational initiation;5.96144683735816e-12!GO:0003743;translation initiation factor activity;6.2203553968619e-12!GO:0051726;regulation of cell cycle;9.36021433001852e-12!GO:0006323;DNA packaging;1.09208801254453e-11!GO:0016072;rRNA metabolic process;1.57479126454809e-11!GO:0000074;regulation of progression through cell cycle;2.20064986638087e-11!GO:0046961;hydrogen ion transporting ATPase activity, rotational mechanism;2.34133867808935e-11!GO:0009150;purine ribonucleotide metabolic process;2.58902244599296e-11!GO:0006464;protein modification process;3.8255790276437e-11!GO:0008565;protein transporter activity;4.94799903071738e-11!GO:0016604;nuclear body;5.87605117905233e-11!GO:0000785;chromatin;8.7444261157453e-11!GO:0005643;nuclear pore;9.45159369791118e-11!GO:0006164;purine nucleotide biosynthetic process;1.10805881557461e-10!GO:0009199;ribonucleoside triphosphate metabolic process;1.12708415552666e-10!GO:0006446;regulation of translational initiation;1.18155832283175e-10!GO:0016192;vesicle-mediated transport;1.37908106164116e-10!GO:0009141;nucleoside triphosphate metabolic process;1.5828508236202e-10!GO:0009260;ribonucleotide biosynthetic process;1.77457536228861e-10!GO:0009205;purine ribonucleoside triphosphate metabolic process;2.16435437817156e-10!GO:0009144;purine nucleoside triphosphate metabolic process;2.16435437817156e-10!GO:0004386;helicase activity;2.41678335143245e-10!GO:0065002;intracellular protein transport across a membrane;2.4980363815467e-10!GO:0046933;hydrogen ion transporting ATP synthase activity, rotational mechanism;4.08571972230291e-10!GO:0005768;endosome;4.48247675106497e-10!GO:0009152;purine ribonucleotide biosynthetic process;4.88833567995329e-10!GO:0051188;cofactor biosynthetic process;4.92570917326379e-10!GO:0055086;nucleobase, nucleoside and nucleotide metabolic process;5.85414856781968e-10!GO:0031988;membrane-bound vesicle;6.62203645734005e-10!GO:0006333;chromatin assembly or disassembly;6.75465414009174e-10!GO:0065004;protein-DNA complex assembly;7.0468343705447e-10!GO:0009055;electron carrier activity;7.0468343705447e-10!GO:0016023;cytoplasmic membrane-bound vesicle;9.3562678121878e-10!GO:0015986;ATP synthesis coupled proton transport;1.72531468613626e-09!GO:0015985;energy coupled proton transport, down electrochemical gradient;1.72531468613626e-09!GO:0009056;catabolic process;1.75380511419328e-09!GO:0046034;ATP metabolic process;1.93390810930647e-09!GO:0009142;nucleoside triphosphate biosynthetic process;2.35968662887025e-09!GO:0009201;ribonucleoside triphosphate biosynthetic process;2.35968662887025e-09!GO:0005793;ER-Golgi intermediate compartment;2.4452939550556e-09!GO:0016876;ligase activity, forming aminoacyl-tRNA and related compounds;2.7004549749743e-09!GO:0004812;aminoacyl-tRNA ligase activity;2.7004549749743e-09!GO:0016875;ligase activity, forming carbon-oxygen bonds;2.7004549749743e-09!GO:0003712;transcription cofactor activity;2.83083274636569e-09!GO:0016879;ligase activity, forming carbon-nitrogen bonds;2.94287934608694e-09!GO:0008639;small protein conjugating enzyme activity;3.22759097304678e-09!GO:0006461;protein complex assembly;3.3542573538498e-09!GO:0008026;ATP-dependent helicase activity;3.53165494838192e-09!GO:0003697;single-stranded DNA binding;4.42822348470358e-09!GO:0009206;purine ribonucleoside triphosphate biosynthetic process;4.46601539770649e-09!GO:0009145;purine nucleoside triphosphate biosynthetic process;4.46601539770649e-09!GO:0006913;nucleocytoplasmic transport;4.50472417624027e-09!GO:0043038;amino acid activation;4.90016007996576e-09!GO:0006418;tRNA aminoacylation for protein translation;4.90016007996576e-09!GO:0043039;tRNA aminoacylation;4.90016007996576e-09!GO:0019787;small conjugating protein ligase activity;5.053770845849e-09!GO:0046930;pore complex;6.33409412653635e-09!GO:0031982;vesicle;6.36609349781888e-09!GO:0050657;nucleic acid transport;6.40516022396114e-09!GO:0051236;establishment of RNA localization;6.40516022396114e-09!GO:0050658;RNA transport;6.40516022396114e-09!GO:0006403;RNA localization;6.40516022396114e-09!GO:0006261;DNA-dependent DNA replication;6.62565729444477e-09!GO:0005773;vacuole;6.63917828313374e-09!GO:0030532;small nuclear ribonucleoprotein complex;6.94527074123573e-09!GO:0016607;nuclear speck;7.14325602979472e-09!GO:0009060;aerobic respiration;7.28497410254063e-09!GO:0015630;microtubule cytoskeleton;8.62596067357815e-09!GO:0051169;nuclear transport;9.08030499012397e-09!GO:0004842;ubiquitin-protein ligase activity;9.12097542658212e-09!GO:0016740;transferase activity;9.80572101060898e-09!GO:0009117;nucleotide metabolic process;9.89259180316664e-09!GO:0043566;structure-specific DNA binding;1.06847268735069e-08!GO:0031410;cytoplasmic vesicle;1.09252034081468e-08!GO:0016787;hydrolase activity;1.14314436835319e-08!GO:0016469;proton-transporting two-sector ATPase complex;1.29670801026776e-08!GO:0019829;cation-transporting ATPase activity;1.35710748858774e-08!GO:0008654;phospholipid biosynthetic process;1.56291862672253e-08!GO:0007005;mitochondrion organization and biogenesis;1.71744363956933e-08!GO:0045333;cellular respiration;1.77866848052759e-08!GO:0044431;Golgi apparatus part;2.61483820949624e-08!GO:0016881;acid-amino acid ligase activity;2.75138315205946e-08!GO:0015078;hydrogen ion transmembrane transporter activity;2.77992619063309e-08!GO:0043687;post-translational protein modification;3.04202905915994e-08!GO:0006754;ATP biosynthetic process;3.62801819319818e-08!GO:0006753;nucleoside phosphate metabolic process;3.62801819319818e-08!GO:0006334;nucleosome assembly;4.82618397614181e-08!GO:0009108;coenzyme biosynthetic process;6.42564671555099e-08!GO:0031497;chromatin assembly;7.14057726193143e-08!GO:0016779;nucleotidyltransferase activity;8.2715606793075e-08!GO:0015931;nucleobase, nucleoside, nucleotide and nucleic acid transport;8.6101061830032e-08!GO:0000323;lytic vacuole;1.09341065351372e-07!GO:0005764;lysosome;1.09341065351372e-07!GO:0012501;programmed cell death;1.22557368390821e-07!GO:0006099;tricarboxylic acid cycle;1.29939080520349e-07!GO:0046356;acetyl-CoA catabolic process;1.29939080520349e-07!GO:0006915;apoptosis;1.43763862386857e-07!GO:0016853;isomerase activity;2.01875557767621e-07!GO:0006084;acetyl-CoA metabolic process;2.35063880215938e-07!GO:0005770;late endosome;2.58657076818198e-07!GO:0051028;mRNA transport;3.0022098259439e-07!GO:0003924;GTPase activity;3.44905022232393e-07!GO:0017038;protein import;3.5939608029247e-07!GO:0048475;coated membrane;3.93477727396901e-07!GO:0030117;membrane coat;3.93477727396901e-07!GO:0006888;ER to Golgi vesicle-mediated transport;3.97160948328267e-07!GO:0008094;DNA-dependent ATPase activity;4.85933197225814e-07!GO:0030120;vesicle coat;6.03342290376553e-07!GO:0030662;coated vesicle membrane;6.03342290376553e-07!GO:0005657;replication fork;7.29406175917417e-07!GO:0016568;chromatin modification;8.26779325358157e-07!GO:0000245;spliceosome assembly;8.29231341942264e-07!GO:0005819;spindle;8.90955575377961e-07!GO:0006752;group transfer coenzyme metabolic process;1.02783105980158e-06!GO:0005788;endoplasmic reticulum lumen;1.07091368497886e-06!GO:0046467;membrane lipid biosynthetic process;1.10078042579078e-06!GO:0043623;cellular protein complex assembly;1.23166353186263e-06!GO:0009109;coenzyme catabolic process;1.34056385759358e-06!GO:0051187;cofactor catabolic process;1.36488582818149e-06!GO:0045259;proton-transporting ATP synthase complex;1.37896073906094e-06!GO:0006366;transcription from RNA polymerase II promoter;1.48482308956696e-06!GO:0051329;interphase of mitotic cell cycle;1.58126528077965e-06!GO:0005762;mitochondrial large ribosomal subunit;1.62449639380515e-06!GO:0000315;organellar large ribosomal subunit;1.62449639380515e-06!GO:0005798;Golgi-associated vesicle;1.66485618263292e-06!GO:0008219;cell death;1.76595055224953e-06!GO:0016265;death;1.76595055224953e-06!GO:0044440;endosomal part;1.80365133474707e-06!GO:0010008;endosome membrane;1.80365133474707e-06!GO:0032446;protein modification by small protein conjugation;1.80365133474707e-06!GO:0046474;glycerophospholipid biosynthetic process;1.8906172445581e-06!GO:0005839;proteasome core complex (sensu Eukaryota);2.16478105501894e-06!GO:0016591;DNA-directed RNA polymerase II, holoenzyme;2.36709622107634e-06!GO:0016567;protein ubiquitination;2.39532376168846e-06!GO:0051325;interphase;2.5864263452991e-06!GO:0016491;oxidoreductase activity;3.20824027147707e-06!GO:0000775;chromosome, pericentric region;3.20824027147707e-06!GO:0000139;Golgi membrane;3.78448178677777e-06!GO:0042440;pigment metabolic process;4.51978668294558e-06!GO:0015077;monovalent inorganic cation transmembrane transporter activity;4.92614791789083e-06!GO:0046148;pigment biosynthetic process;5.35429181989113e-06!GO:0051246;regulation of protein metabolic process;6.01968201487324e-06!GO:0048523;negative regulation of cellular process;6.45034171158897e-06!GO:0006916;anti-apoptosis;6.61087003145541e-06!GO:0003899;DNA-directed RNA polymerase activity;7.40002529270178e-06!GO:0005667;transcription factor complex;7.62836946726181e-06!GO:0031202;RNA splicing factor activity, transesterification mechanism;9.85335180465749e-06!GO:0004298;threonine endopeptidase activity;1.08691345181672e-05!GO:0005525;GTP binding;1.15356502135021e-05!GO:0030659;cytoplasmic vesicle membrane;1.22377466614487e-05!GO:0006613;cotranslational protein targeting to membrane;1.43289541338505e-05!GO:0016772;transferase activity, transferring phosphorus-containing groups;1.70928633030216e-05!GO:0050794;regulation of cellular process;1.75677158038105e-05!GO:0019843;rRNA binding;1.80817746360608e-05!GO:0000151;ubiquitin ligase complex;1.91391776254672e-05!GO:0003724;RNA helicase activity;1.93178018156006e-05!GO:0003755;peptidyl-prolyl cis-trans isomerase activity;2.09000291591557e-05!GO:0000075;cell cycle checkpoint;2.19561474356e-05!GO:0015980;energy derivation by oxidation of organic compounds;2.28349908652467e-05!GO:0000314;organellar small ribosomal subunit;2.395046584016e-05!GO:0005763;mitochondrial small ribosomal subunit;2.395046584016e-05!GO:0008033;tRNA processing;2.52592469599507e-05!GO:0031252;leading edge;2.64176400581659e-05!GO:0006650;glycerophospholipid metabolic process;3.05403734548603e-05!GO:0016859;cis-trans isomerase activity;3.2714334765127e-05!GO:0045786;negative regulation of progression through cell cycle;3.39951286524884e-05!GO:0006643;membrane lipid metabolic process;3.51122862684701e-05!GO:0005813;centrosome;3.61182959716636e-05!GO:0043021;ribonucleoprotein binding;3.73849816688378e-05!GO:0008610;lipid biosynthetic process;4.07144435946632e-05!GO:0031968;organelle outer membrane;4.31201493096251e-05!GO:0006612;protein targeting to membrane;4.33290352075521e-05!GO:0046489;phosphoinositide biosynthetic process;4.49379076540092e-05!GO:0005769;early endosome;4.76587339030397e-05!GO:0005815;microtubule organizing center;5.07525286294316e-05!GO:0044433;cytoplasmic vesicle part;5.27024795543777e-05!GO:0006793;phosphorus metabolic process;5.33813886591487e-05!GO:0006796;phosphate metabolic process;5.33813886591487e-05!GO:0006626;protein targeting to mitochondrion;5.54784619129519e-05!GO:0043123;positive regulation of I-kappaB kinase/NF-kappaB cascade;5.61341393037057e-05!GO:0012506;vesicle membrane;5.75063452428553e-05!GO:0019867;outer membrane;5.76010565642749e-05!GO:0030867;rough endoplasmic reticulum membrane;6.83582278617696e-05!GO:0042802;identical protein binding;7.13802130310587e-05!GO:0044452;nucleolar part;7.13802130310587e-05!GO:0006302;double-strand break repair;7.79866297903505e-05!GO:0006091;generation of precursor metabolites and energy;8.05827875380761e-05!GO:0048066;pigmentation during development;8.61617784881013e-05!GO:0043122;regulation of I-kappaB kinase/NF-kappaB cascade;8.66457500626144e-05!GO:0045454;cell redox homeostasis;8.69465696568758e-05!GO:0030133;transport vesicle;9.53613167530756e-05!GO:0051427;hormone receptor binding;9.64672551265882e-05!GO:0009165;nucleotide biosynthetic process;0.000104469787268731!GO:0015631;tubulin binding;0.000104662955937624!GO:0042981;regulation of apoptosis;0.000106395853528579!GO:0015405;P-P-bond-hydrolysis-driven transmembrane transporter activity;0.000110434663927758!GO:0015399;primary active transmembrane transporter activity;0.000110434663927758!GO:0043069;negative regulation of programmed cell death;0.000112324065408217!GO:0032561;guanyl ribonucleotide binding;0.000115022251658174!GO:0019001;guanyl nucleotide binding;0.000115022251658174!GO:0016563;transcription activator activity;0.000116971355069945!GO:0003714;transcription corepressor activity;0.000122454161364946!GO:0003713;transcription coactivator activity;0.000125940937765435!GO:0003684;damaged DNA binding;0.000125956100570423!GO:0005741;mitochondrial outer membrane;0.000125956100570423!GO:0043067;regulation of programmed cell death;0.000126651992122457!GO:0048471;perinuclear region of cytoplasm;0.000128450993428297!GO:0048519;negative regulation of biological process;0.000128634540094211!GO:0006839;mitochondrial transport;0.000135608424818913!GO:0007051;spindle organization and biogenesis;0.000136600981340023!GO:0043066;negative regulation of apoptosis;0.000136948799203913!GO:0006310;DNA recombination;0.000136948799203913!GO:0051170;nuclear import;0.000158818577449773!GO:0006383;transcription from RNA polymerase III promoter;0.00016123580873589!GO:0016363;nuclear matrix;0.000178937275369466!GO:0016564;transcription repressor activity;0.000184240994738295!GO:0000786;nucleosome;0.000192079639393949!GO:0051168;nuclear export;0.00019366266836483!GO:0035257;nuclear hormone receptor binding;0.000196993849668854!GO:0043681;protein import into mitochondrion;0.000202484218604524!GO:0019899;enzyme binding;0.000206223213423727!GO:0003690;double-stranded DNA binding;0.000206596776264242!GO:0044262;cellular carbohydrate metabolic process;0.000212977429887794!GO:0042625;ATPase activity, coupled to transmembrane movement of ions;0.000225660350474341!GO:0003682;chromatin binding;0.000227904200621394!GO:0019748;secondary metabolic process;0.000258715041842813!GO:0000059;protein import into nucleus, docking;0.000284383608344703!GO:0006606;protein import into nucleus;0.000284383608344703!GO:0030530;heterogeneous nuclear ribonucleoprotein complex;0.000307947049741567!GO:0033178;proton-transporting two-sector ATPase complex, catalytic domain;0.000312217702769337!GO:0051789;response to protein stimulus;0.000318355697982295!GO:0006986;response to unfolded protein;0.000318355697982295!GO:0005905;coated pit;0.000320305765457721!GO:0016310;phosphorylation;0.000323418206009769!GO:0005885;Arp2/3 protein complex;0.000332516816879245!GO:0031324;negative regulation of cellular metabolic process;0.000347123367830248!GO:0005753;mitochondrial proton-transporting ATP synthase complex;0.000357351097706112!GO:0004527;exonuclease activity;0.0003910847951509!GO:0031072;heat shock protein binding;0.000406697604977361!GO:0004576;oligosaccharyl transferase activity;0.000412289769612411!GO:0003678;DNA helicase activity;0.000416867635539529!GO:0008186;RNA-dependent ATPase activity;0.00045623035611254!GO:0033116;ER-Golgi intermediate compartment membrane;0.000470465163193879!GO:0007034;vacuolar transport;0.0004865433454077!GO:0007059;chromosome segregation;0.000492389187023363!GO:0008250;oligosaccharyl transferase complex;0.000501816293440855!GO:0005874;microtubule;0.000539351242681152!GO:0045261;proton-transporting ATP synthase complex, catalytic core F(1);0.000570827708930821!GO:0033162;melanosome membrane;0.000570827708930821!GO:0045009;chitosome;0.000570827708930821!GO:0030880;RNA polymerase complex;0.0005760943706768!GO:0043284;biopolymer biosynthetic process;0.000585582534784546!GO:0016126;sterol biosynthetic process;0.000602554684636929!GO:0007006;mitochondrial membrane organization and biogenesis;0.0006177043196896!GO:0000776;kinetochore;0.000644265888447218!GO:0005791;rough endoplasmic reticulum;0.000694515465210927!GO:0004579;dolichyl-diphosphooligosaccharide-protein glycotransferase activity;0.000735807042396319!GO:0005048;signal sequence binding;0.000746560207040314!GO:0006818;hydrogen transport;0.000766173981468956!GO:0030384;phosphoinositide metabolic process;0.000779819683626853!GO:0006506;GPI anchor biosynthetic process;0.000791898177304321!GO:0051920;peroxiredoxin activity;0.00080457050108869!GO:0046519;sphingoid metabolic process;0.000806735098122907!GO:0007249;I-kappaB kinase/NF-kappaB cascade;0.000817548874515901!GO:0007040;lysosome organization and biogenesis;0.000848631922491642!GO:0000079;regulation of cyclin-dependent protein kinase activity;0.000868720712301457!GO:0051052;regulation of DNA metabolic process;0.000872471093899396!GO:0007010;cytoskeleton organization and biogenesis;0.000878933143955827!GO:0006672;ceramide metabolic process;0.000904587728914641!GO:0030118;clathrin coat;0.000918291431197892!GO:0004518;nuclease activity;0.000960814945287449!GO:0042158;lipoprotein biosynthetic process;0.000990788961891264!GO:0031902;late endosome membrane;0.000991936519281674!GO:0016679;oxidoreductase activity, acting on diphenols and related substances as donors;0.00103540447707516!GO:0016681;oxidoreductase activity, acting on diphenols and related substances as donors, cytochrome as acceptor;0.00103540447707516!GO:0008121;ubiquinol-cytochrome-c reductase activity;0.00103540447707516!GO:0032508;DNA duplex unwinding;0.00104372299750995!GO:0032392;DNA geometric change;0.00104372299750995!GO:0005852;eukaryotic translation initiation factor 3 complex;0.00107962903486364!GO:0006414;translational elongation;0.00114763830894168!GO:0009892;negative regulation of metabolic process;0.00116594259067668!GO:0030658;transport vesicle membrane;0.00116594259067668!GO:0043492;ATPase activity, coupled to movement of substances;0.00116594259067668!GO:0006505;GPI anchor metabolic process;0.00119158367829582!GO:0015992;proton transport;0.00119375562785371!GO:0006497;protein amino acid lipidation;0.00119375562785371!GO:0004004;ATP-dependent RNA helicase activity;0.00122856295698711!GO:0007033;vacuole organization and biogenesis;0.00125915685147808!GO:0005774;vacuolar membrane;0.00131548523737344!GO:0003729;mRNA binding;0.00132128898234117!GO:0055029;nuclear DNA-directed RNA polymerase complex;0.00133925758874782!GO:0000428;DNA-directed RNA polymerase complex;0.00133925758874782!GO:0005838;proteasome regulatory particle (sensu Eukaryota);0.00136711069309903!GO:0006644;phospholipid metabolic process;0.00139646083304683!GO:0005637;nuclear inner membrane;0.00140646787422271!GO:0042626;ATPase activity, coupled to transmembrane movement of substances;0.00141685786412879!GO:0005684;U2-dependent spliceosome;0.00153504133632372!GO:0007088;regulation of mitosis;0.00154325586853063!GO:0006268;DNA unwinding during replication;0.00156297990264493!GO:0045934;negative regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process;0.00163902836563004!GO:0006270;DNA replication initiation;0.00169116756136897!GO:0016197;endosome transport;0.0017327548783635!GO:0016820;hydrolase activity, acting on acid anhydrides, catalyzing transmembrane movement of substances;0.00178055745042373!GO:0019752;carboxylic acid metabolic process;0.00185487853162205!GO:0016281;eukaryotic translation initiation factor 4F complex;0.00188604858415688!GO:0031970;organelle envelope lumen;0.00191513269519861!GO:0051252;regulation of RNA metabolic process;0.00197425237988265!GO:0006082;organic acid metabolic process;0.00202619652401649!GO:0016741;transferase activity, transferring one-carbon groups;0.00218691520857831!GO:0000228;nuclear chromosome;0.0022013163877665!GO:0018196;peptidyl-asparagine modification;0.00229521800754843!GO:0018279;protein amino acid N-linked glycosylation via asparagine;0.00229521800754843!GO:0008168;methyltransferase activity;0.00253897752140221!GO:0045263;proton-transporting ATP synthase complex, coupling factor F(o);0.00280524251259701!GO:0033177;proton-transporting two-sector ATPase complex, proton-transporting domain;0.00280524251259701!GO:0035258;steroid hormone receptor binding;0.00284414181664202!GO:0006402;mRNA catabolic process;0.00287903731159397!GO:0048487;beta-tubulin binding;0.00297190082363995!GO:0043596;nuclear replication fork;0.00302488819704742!GO:0006509;membrane protein ectodomain proteolysis;0.0030350963764538!GO:0033619;membrane protein proteolysis;0.0030350963764538!GO:0008092;cytoskeletal protein binding;0.00311835285165722!GO:0006695;cholesterol biosynthetic process;0.00336978109296195!GO:0016891;endoribonuclease activity, producing 5'-phosphomonoesters;0.00340474790744909!GO:0043161;proteasomal ubiquitin-dependent protein catabolic process;0.00341348766281034!GO:0048500;signal recognition particle;0.00342764843007705!GO:0006284;base-excision repair;0.00350977209065307!GO:0000226;microtubule cytoskeleton organization and biogenesis;0.00353825877197441!GO:0030176;integral to endoplasmic reticulum membrane;0.00357384297497053!GO:0007041;lysosomal transport;0.00368287236430276!GO:0006352;transcription initiation;0.00372617367267803!GO:0006611;protein export from nucleus;0.00372931999921827!GO:0030660;Golgi-associated vesicle membrane;0.00379016140818082!GO:0008312;7S RNA binding;0.00381249651652565!GO:0007093;mitotic cell cycle checkpoint;0.00386387970808979!GO:0044437;vacuolar part;0.00396331380434842!GO:0042393;histone binding;0.00409421431578975!GO:0006401;RNA catabolic process;0.00416883165688766!GO:0022890;inorganic cation transmembrane transporter activity;0.00416999060433279!GO:0008022;protein C-terminus binding;0.00427022983869568!GO:0043488;regulation of mRNA stability;0.004309125662479!GO:0043487;regulation of RNA stability;0.004309125662479!GO:0008361;regulation of cell size;0.00440302467903294!GO:0016796;exonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters;0.00447095207880969!GO:0005876;spindle microtubule;0.00450604937330432!GO:0000307;cyclin-dependent protein kinase holoenzyme complex;0.00456794003532399!GO:0030036;actin cytoskeleton organization and biogenesis;0.00469820097480695!GO:0050662;coenzyme binding;0.00469880145552244!GO:0005758;mitochondrial intermembrane space;0.00473886003302154!GO:0006289;nucleotide-excision repair;0.00477242694398458!GO:0008180;signalosome;0.00478951526457326!GO:0050789;regulation of biological process;0.00480593252637324!GO:0000178;exosome (RNase complex);0.00487652724573469!GO:0016765;transferase activity, transferring alkyl or aryl (other than methyl) groups;0.00502037478097613!GO:0065009;regulation of a molecular function;0.00504416171057318!GO:0000049;tRNA binding;0.0051077257531503!GO:0030663;COPI coated vesicle membrane;0.00523818290368031!GO:0030126;COPI vesicle coat;0.00523818290368031!GO:0030119;AP-type membrane coat adaptor complex;0.00532624250246971!GO:0016860;intramolecular oxidoreductase activity;0.00543134699103331!GO:0005765;lysosomal membrane;0.00545555575608223!GO:0016627;oxidoreductase activity, acting on the CH-CH group of donors;0.00551513850595731!GO:0051287;NAD binding;0.0055651632593205!GO:0019222;regulation of metabolic process;0.00564102081663492!GO:0006275;regulation of DNA replication;0.00574781141792018!GO:0006614;SRP-dependent cotranslational protein targeting to membrane;0.00596459578742695!GO:0045047;protein targeting to ER;0.00596459578742695!GO:0000922;spindle pole;0.00597893336358501!GO:0001726;ruffle;0.00614249280779119!GO:0006891;intra-Golgi vesicle-mediated transport;0.00615022087016553!GO:0006520;amino acid metabolic process;0.00618290973464401!GO:0004003;ATP-dependent DNA helicase activity;0.00620492749197618!GO:0006338;chromatin remodeling;0.00620492749197618!GO:0007052;mitotic spindle organization and biogenesis;0.00620965361610376!GO:0006357;regulation of transcription from RNA polymerase II promoter;0.00628389751454892!GO:0016049;cell growth;0.00644260621942908!GO:0051539;4 iron, 4 sulfur cluster binding;0.00682713523136664!GO:0000287;magnesium ion binding;0.00685787343539572!GO:0000082;G1/S transition of mitotic cell cycle;0.00696508393994432!GO:0005869;dynactin complex;0.00715853760951986!GO:0048069;eye pigmentation;0.0072753381131767!GO:0051087;chaperone binding;0.00741958454688324!GO:0006582;melanin metabolic process;0.00752795862308106!GO:0006583;melanin biosynthetic process from tyrosine;0.00752795862308106!GO:0042438;melanin biosynthetic process;0.00752795862308106!GO:0046483;heterocycle metabolic process;0.00754110101954552!GO:0030131;clathrin adaptor complex;0.00754476226430466!GO:0009116;nucleoside metabolic process;0.0075940915737582!GO:0030521;androgen receptor signaling pathway;0.00788164011697789!GO:0043022;ribosome binding;0.00790209028530385!GO:0001558;regulation of cell growth;0.00812014543379279!GO:0048154;S100 beta binding;0.0081571308404334!GO:0031301;integral to organelle membrane;0.00821528845159318!GO:0006778;porphyrin metabolic process;0.00834633415500538!GO:0033013;tetrapyrrole metabolic process;0.00834633415500538!GO:0006890;retrograde vesicle-mediated transport, Golgi to ER;0.00853278023554583!GO:0016481;negative regulation of transcription;0.00860605434772577!GO:0016893;endonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters;0.00868654050997406!GO:0016780;phosphotransferase activity, for other substituted phosphate groups;0.00868654050997406!GO:0008017;microtubule binding;0.00891418068645853!GO:0005832;chaperonin-containing T-complex;0.00903167110661131!GO:0006405;RNA export from nucleus;0.00913680488612748!GO:0044454;nuclear chromosome part;0.00913680488612748!GO:0030125;clathrin vesicle coat;0.00928228904130265!GO:0030665;clathrin coated vesicle membrane;0.00928228904130265!GO:0006220;pyrimidine nucleotide metabolic process;0.009307392383534!GO:0006144;purine base metabolic process;0.00935137669019711!GO:0003711;transcription elongation regulator activity;0.00955164456470754!GO:0004177;aminopeptidase activity;0.00985303376323386!GO:0005786;signal recognition particle, endoplasmic reticulum targeting;0.0100287745137175!GO:0017166;vinculin binding;0.0100369398304315!GO:0007346;regulation of progression through mitotic cell cycle;0.0100615180814422!GO:0016251;general RNA polymerase II transcription factor activity;0.0101702446872!GO:0016272;prefoldin complex;0.0105446115531441!GO:0006726;eye pigment biosynthetic process;0.0105446115531441!GO:0042441;eye pigment metabolic process;0.0105446115531441!GO:0003746;translation elongation factor activity;0.0105446115531441!GO:0006007;glucose catabolic process;0.0105446115531441!GO:0016676;oxidoreductase activity, acting on heme group of donors, oxygen as acceptor;0.0110015688622908!GO:0015002;heme-copper terminal oxidase activity;0.0110015688622908!GO:0016675;oxidoreductase activity, acting on heme group of donors;0.0110015688622908!GO:0004129;cytochrome-c oxidase activity;0.0110015688622908!GO:0008408;3'-5' exonuclease activity;0.0110395844568704!GO:0051540;metal cluster binding;0.0110585842690342!GO:0051536;iron-sulfur cluster binding;0.0110585842690342!GO:0006779;porphyrin biosynthetic process;0.0121737460189915!GO:0033014;tetrapyrrole biosynthetic process;0.0121737460189915!GO:0031124;mRNA 3'-end processing;0.0121853287770263!GO:0004532;exoribonuclease activity;0.0122133724486633!GO:0016896;exoribonuclease activity, producing 5'-phosphomonoesters;0.0122133724486633!GO:0007017;microtubule-based process;0.0122133724486633!GO:0043601;nuclear replisome;0.0123826828041696!GO:0030894;replisome;0.0123826828041696!GO:0030496;midbody;0.0124284454785765!GO:0008139;nuclear localization sequence binding;0.0127560335234203!GO:0030137;COPI-coated vesicle;0.0128453825378958!GO:0030132;clathrin coat of coated pit;0.0129318413162838!GO:0007050;cell cycle arrest;0.0129723020035952!GO:0007243;protein kinase cascade;0.0133431908064662!GO:0000725;recombinational repair;0.0134254895062166!GO:0000724;double-strand break repair via homologous recombination;0.0134254895062166!GO:0030145;manganese ion binding;0.0136183056164402!GO:0000339;RNA cap binding;0.0137413244667556!GO:0005663;DNA replication factor C complex;0.0142856440748284!GO:0006665;sphingolipid metabolic process;0.0143499857881335!GO:0000910;cytokinesis;0.0144010750353426!GO:0030140;trans-Golgi network transport vesicle;0.0146898351484593!GO:0008320;protein transmembrane transporter activity;0.0153768313747278!GO:0009112;nucleobase metabolic process;0.0154362274967857!GO:0030027;lamellipodium;0.0155292487526725!GO:0009451;RNA modification;0.0157608513120334!GO:0019206;nucleoside kinase activity;0.0161962278696368!GO:0031901;early endosome membrane;0.0161962278696368!GO:0030029;actin filament-based process;0.0168666878869569!GO:0006740;NADPH regeneration;0.0170664993779365!GO:0006098;pentose-phosphate shunt;0.0170664993779365!GO:0050681;androgen receptor binding;0.0170767987619209!GO:0016584;nucleosome positioning;0.0175901894826726!GO:0008234;cysteine-type peptidase activity;0.0181649880558508!GO:0031529;ruffle organization and biogenesis;0.0183400867631978!GO:0000030;mannosyltransferase activity;0.0183902037077368!GO:0009303;rRNA transcription;0.018715542887908!GO:0016862;intramolecular oxidoreductase activity, interconverting keto- and enol-groups;0.0192387035661807!GO:0030149;sphingolipid catabolic process;0.019319765267391!GO:0005975;carbohydrate metabolic process;0.0194622156779759!GO:0007021;tubulin folding;0.0198095955170065!GO:0032981;mitochondrial respiratory chain complex I assembly;0.0199706201424214!GO:0010257;NADH dehydrogenase complex assembly;0.0199706201424214!GO:0033108;mitochondrial respiratory chain complex assembly;0.0199706201424214!GO:0030134;ER to Golgi transport vesicle;0.0199706201424214!GO:0008047;enzyme activator activity;0.0199826426260047!GO:0008632;apoptotic program;0.0204379167944081!GO:0005665;DNA-directed RNA polymerase II, core complex;0.020612395743151!GO:0022406;membrane docking;0.0207000058597403!GO:0048278;vesicle docking;0.0207000058597403!GO:0003955;NAD(P)H dehydrogenase (quinone) activity;0.0210429584162329!GO:0051452;cellular pH reduction;0.02153474515912!GO:0051453;regulation of cellular pH;0.02153474515912!GO:0045851;pH reduction;0.02153474515912!GO:0004523;ribonuclease H activity;0.021634455154949!GO:0019205;nucleobase, nucleoside, nucleotide kinase activity;0.0216384774388749!GO:0006376;mRNA splice site selection;0.0218674123338054!GO:0000389;nuclear mRNA 3'-splice site recognition;0.0218674123338054!GO:0006595;polyamine metabolic process;0.0224427603548062!GO:0007264;small GTPase mediated signal transduction;0.0230588319165825!GO:0030508;thiol-disulfide exchange intermediate activity;0.0231241916690201!GO:0050811;GABA receptor binding;0.0231892103847992!GO:0051053;negative regulation of DNA metabolic process;0.0236130024799946!GO:0004674;protein serine/threonine kinase activity;0.0236450375051198!GO:0042026;protein refolding;0.0238058984649331!GO:0006914;autophagy;0.023823361242277!GO:0016408;C-acyltransferase activity;0.0238661039104929!GO:0005669;transcription factor TFIID complex;0.0242451820350304!GO:0050931;pigment cell differentiation;0.0246443906009045!GO:0030318;melanocyte differentiation;0.0246443906009045!GO:0007007;inner mitochondrial membrane organization and biogenesis;0.0247628451306457!GO:0030127;COPII vesicle coat;0.0247628451306457!GO:0012507;ER to Golgi transport vesicle membrane;0.0247628451306457!GO:0006733;oxidoreduction coenzyme metabolic process;0.0252401948411464!GO:0001573;ganglioside metabolic process;0.0257229093241967!GO:0044255;cellular lipid metabolic process;0.0263891634865432!GO:0016044;membrane organization and biogenesis;0.0264905208618121!GO:0043126;regulation of 1-phosphatidylinositol 4-kinase activity;0.0264905208618121!GO:0046813;virion attachment, binding of host cell surface receptor;0.0264905208618121!GO:0043128;positive regulation of 1-phosphatidylinositol 4-kinase activity;0.0264905208618121!GO:0042168;heme metabolic process;0.0265090513877677!GO:0030518;steroid hormone receptor signaling pathway;0.0269250599118685!GO:0006378;mRNA polyadenylation;0.0270663814055952!GO:0004503;monophenol monooxygenase activity;0.0274314933685659!GO:0016716;oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, another compound as one donor, and incorporation of one atom of oxygen;0.0274314933685659!GO:0006730;one-carbon compound metabolic process;0.0275578157115615!GO:0000096;sulfur amino acid metabolic process;0.0279881701855355!GO:0000118;histone deacetylase complex;0.0281145303340892!GO:0032984;macromolecular complex disassembly;0.0281405531457944!GO:0050790;regulation of catalytic activity;0.0288103493205986!GO:0006904;vesicle docking during exocytosis;0.0289631566924561!GO:0004448;isocitrate dehydrogenase activity;0.0291353969838007!GO:0031371;ubiquitin conjugating enzyme complex;0.0298565413462875!GO:0031570;DNA integrity checkpoint;0.0299617120943834!GO:0000792;heterochromatin;0.0300055206958395!GO:0004722;protein serine/threonine phosphatase activity;0.0306587618044436!GO:0045045;secretory pathway;0.0306587618044436!GO:0008538;proteasome activator activity;0.0306686076494131!GO:0043414;biopolymer methylation;0.0310382270751811!GO:0000726;non-recombinational repair;0.0311025902338682!GO:0001725;stress fiber;0.0316445958251272!GO:0032432;actin filament bundle;0.0316445958251272!GO:0006360;transcription from RNA polymerase I promoter;0.0316877543619708!GO:0048522;positive regulation of cellular process;0.032551070620798!GO:0000084;S phase of mitotic cell cycle;0.0327477327899828!GO:0030911;TPR domain binding;0.0327584351211815!GO:0003923;GPI-anchor transamidase activity;0.0330392735684556!GO:0016255;attachment of GPI anchor to protein;0.0330392735684556!GO:0042765;GPI-anchor transamidase complex;0.0330392735684556!GO:0003887;DNA-directed DNA polymerase activity;0.0330701195970298!GO:0004549;tRNA-specific ribonuclease activity;0.0333727206636004!GO:0006767;water-soluble vitamin metabolic process;0.0341608547233168!GO:0005652;nuclear lamina;0.0346026324802249!GO:0043624;cellular protein complex disassembly;0.0346093825469778!GO:0006807;nitrogen compound metabolic process;0.0347701717677462!GO:0030503;regulation of cell redox homeostasis;0.0349753640888842!GO:0004526;ribonuclease P activity;0.0352619436182256!GO:0033673;negative regulation of kinase activity;0.0354493970392959!GO:0006469;negative regulation of protein kinase activity;0.0354493970392959!GO:0000209;protein polyubiquitination;0.0359930579131791!GO:0032259;methylation;0.0363126518239727!GO:0009262;deoxyribonucleotide metabolic process;0.0366499103677673!GO:0005996;monosaccharide metabolic process;0.0375590238374547!GO:0031123;RNA 3'-end processing;0.037605482350576!GO:0019318;hexose metabolic process;0.037605482350576!GO:0008287;protein serine/threonine phosphatase complex;0.0376697184300493!GO:0005784;translocon complex;0.037814764000127!GO:0035035;histone acetyltransferase binding;0.0380363519685018!GO:0009308;amine metabolic process;0.0382848414727194!GO:0032200;telomere organization and biogenesis;0.0385716011548466!GO:0000723;telomere maintenance;0.0385716011548466!GO:0006783;heme biosynthetic process;0.0392279676678457!GO:0008299;isoprenoid biosynthetic process;0.0403787596151012!GO:0006984;ER-nuclear signaling pathway;0.0404259839885714!GO:0040029;regulation of gene expression, epigenetic;0.0407125845346828!GO:0050178;phenylpyruvate tautomerase activity;0.0407983431842252!GO:0051348;negative regulation of transferase activity;0.0408276794854203!GO:0030433;ER-associated protein catabolic process;0.0408276794854203!GO:0006515;misfolded or incompletely synthesized protein catabolic process;0.0408276794854203!GO:0016835;carbon-oxygen lyase activity;0.0415760383514968!GO:0051320;S phase;0.0417495411955646!GO:0000175;3'-5'-exoribonuclease activity;0.0420087157326621!GO:0009124;nucleoside monophosphate biosynthetic process;0.0436370508159572!GO:0009123;nucleoside monophosphate metabolic process;0.0436370508159572!GO:0040008;regulation of growth;0.0442344553579672!GO:0008757;S-adenosylmethionine-dependent methyltransferase activity;0.0442470536312911!GO:0045947;negative regulation of translational initiation;0.0443369975586539!GO:0033559;unsaturated fatty acid metabolic process;0.0456655264143511!GO:0006636;unsaturated fatty acid biosynthetic process;0.0456655264143511!GO:0046983;protein dimerization activity;0.0461520626662316!GO:0006979;response to oxidative stress;0.0461833740742444!GO:0051318;G1 phase;0.0461833740742444!GO:0000781;chromosome, telomeric region;0.0461833740742444!GO:0046479;glycosphingolipid catabolic process;0.0470097433997877!GO:0016706;oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, 2-oxoglutarate as one donor, and incorporation of one atom each of oxygen into both donors;0.047371154263776!GO:0048037;cofactor binding;0.048256841862748!GO:0043241;protein complex disassembly;0.0483697863247412!GO:0000793;condensed chromosome;0.0488173381581082!GO:0003988;acetyl-CoA C-acyltransferase activity;0.0492333395037392!GO:0033170;DNA-protein loading ATPase activity;0.049256467582892!GO:0003689;DNA clamp loader activity;0.049256467582892!GO:0004540;ribonuclease activity;0.049256467582892!GO:0003857;3-hydroxyacyl-CoA dehydrogenase activity;0.0498258353266748 | |||
|sample_id=12641 | |||
|sample_note= | |||
|sample_sex=male | |||
|sample_species=Human (Homo sapiens) | |||
|sample_strain= | |||
|sample_tissue=skin | |||
|timecourse=Melanocytic_differentiation | |||
|top_motifs=HOX{A6,A7,B6,B7}:2.56578222217;PAX6:2.14961939183;ARNT_ARNT2_BHLHB2_MAX_MYC_USF1:2.05996203256;NR3C1:1.97457264012;ESRRA:1.72823459809;NFE2L1:1.3864946309;TFDP1:1.3535937005;E2F1..5:1.21144097647;SREBF1,2:1.19424407075;POU3F1..4:1.16867051608;XCPE1{core}:1.12254924234;bHLH_family:1.10903685463;PAX8:1.08180688991;EN1,2:1.0535688635;RXR{A,B,G}:1.04264537041;ALX4:1.0227188549;ZNF423:0.966676292599;GFI1:0.943526939435;NR5A1,2:0.859146001534;PBX1:0.83243908499;NFIX:0.735909590872;HOX{A4,D4}:0.735746884761;NKX2-3_NKX2-5:0.666415416403;ELK1,4_GABP{A,B1}:0.662938307732;HES1:0.647914893043;UFEwm:0.621909744415;ZNF143:0.614865585311;PAX1,9:0.551295873074;NKX2-2,8:0.512618737964;EVI1:0.500706436925;CDC5L:0.478498859762;FOXQ1:0.459795255241;NRF1:0.450020633646;NFY{A,B,C}:0.441535645015;PAX5:0.400479220903;SOX{8,9,10}:0.392924030953;TEF:0.364072484554;XBP1:0.289635007321;GTF2A1,2:0.278179542947;ZNF238:0.274319946187;HNF4A_NR2F1,2:0.256708345578;NANOG:0.240685548501;STAT1,3:0.217724273388;ARID5B:0.209056851208;HSF1,2:0.200296117759;PRRX1,2:0.199970485543;ZIC1..3:0.19910593498;TLX1..3_NFIC{dimer}:0.187118240606;YY1:0.175025043463;ONECUT1,2:0.113426898435;TP53:0.107896265457;JUN:0.107119892647;HBP1_HMGB_SSRP1_UBTF:0.102758196918;BREu{core}:0.10172025708;ESR1:0.0866567635895;OCT4_SOX2{dimer}:0.0766190190503;AR:0.0501170408738;SOX5:0.0484390944931;SP1:0.0471700490467;CREB1:0.0411039568688;REST:0.0363390529456;FOXL1:0.0346849543012;LEF1_TCF7_TCF7L1,2:0.0286664136535;LHX3,4:0.0275828095398;KLF4:0.0253877517929;TOPORS:0.0238455458432;NKX3-1:0.0225324228441;ZBTB6:0.0143432529175;MYB:-0.00827094699405;BACH2:-0.0125744848081;GTF2I:-0.0168148483411;STAT5{A,B}:-0.027521677885;TAL1_TCF{3,4,12}:-0.0317087664323;HIC1:-0.0404501521195;FOXM1:-0.0528874173498;VSX1,2:-0.0569197912228;PPARG:-0.071038882939;TEAD1:-0.0713210353698;FOX{F1,F2,J1}:-0.0733879379393;ZFP161:-0.0750807072917;HOX{A5,B5}:-0.0767997689985;PAX4:-0.0895999220667;RORA:-0.0966075572666;TFAP2B:-0.0976409097755;IKZF1:-0.097879065097;RFX2..5_RFXANK_RFXAP:-0.101149139988;EBF1:-0.104326605644;ZBTB16:-0.109661770257;TFCP2:-0.122878586349;EP300:-0.131327049465;RXR{A,B,G}_{NR1H2,PPAR}dimers:-0.149370051882;POU6F1:-0.152022261743;HNF1A:-0.162782752836;CUX2:-0.16607573637;ATF4:-0.170911472426;GFI1B:-0.171913063311;FOSL2:-0.173771030458;POU2F1..3:-0.180109497575;ELF1,2,4:-0.18936057347;SOX17:-0.194708022431;RUNX1..3:-0.195240324111;NHLH1,2:-0.198002870833;POU1F1:-0.202036115747;NKX3-2:-0.20707920102;FOS_FOS{B,L1}_JUN{B,D}:-0.207528255989;PAX2:-0.210685713838;SMAD1..7,9:-0.211417077761;ADNP_IRX_SIX_ZHX:-0.231395341525;FOXA2:-0.247535890869;AHR_ARNT_ARNT2:-0.250233967218;RFX1:-0.255623584671;NFIL3:-0.266101085728;MEF2{A,B,C,D}:-0.279414795339;MTF1:-0.279619987836;SOX2:-0.283867889073;CRX:-0.289367517137;DMAP1_NCOR{1,2}_SMARC:-0.292837677481;NR6A1:-0.295142977908;RXRA_VDR{dimer}:-0.300131921004;ZNF148:-0.308236345049;GCM1,2:-0.313434892153;HAND1,2:-0.314725617146;NFE2:-0.320343407002;SPZ1:-0.320872138547;ZNF384:-0.322253538245;SPIB:-0.324325915143;MYBL2:-0.327387283873;NFE2L2:-0.332880125418;LMO2:-0.333005326057;SPI1:-0.336559266803;PRDM1:-0.351208910513;ALX1:-0.357393146495;HMX1:-0.364311643506;FOXP3:-0.388183996867;IKZF2:-0.395493043537;NR1H4:-0.409182346121;RBPJ:-0.424151272064;ATF5_CREB3:-0.432684870532;FOXD3:-0.441110112743;GLI1..3:-0.443186069124;HMGA1,2:-0.445186781575;HLF:-0.483628309764;NKX2-1,4:-0.485184769753;NFKB1_REL_RELA:-0.504858805941;GATA6:-0.51722890684;GATA4:-0.517816303471;ETS1,2:-0.518073314732;GZF1:-0.522755616316;SNAI1..3:-0.539021391601;T:-0.565153847972;EGR1..3:-0.570167156561;HOXA9_MEIS1:-0.570449383508;IRF7:-0.586388184954;MYOD1:-0.586768647557;BPTF:-0.594069197015;HIF1A:-0.59877976764;CEBPA,B_DDIT3:-0.60187580973;TFAP2{A,C}:-0.604264594508;MAZ:-0.613912460743;NFATC1..3:-0.619537689179;MED-1{core}:-0.622411146246;FOX{I1,J2}:-0.625579654322;SRF:-0.631488695657;ZEB1:-0.644507383929;TBP:-0.654531170949;NANOG{mouse}:-0.658293957525;MAFB:-0.674378823665;IRF1,2:-0.680471760949;FOX{D1,D2}:-0.682229795368;TFAP4:-0.683351269704;PAX3,7:-0.687785035376;RREB1:-0.690249396809;AIRE:-0.704071414944;TBX4,5:-0.710008477594;NKX6-1,2:-0.719804906529;STAT2,4,6:-0.720855686955;MTE{core}:-0.724523489172;FOXO1,3,4:-0.729248771673;PITX1..3:-0.774305243968;ATF2:-0.776593167776;CDX1,2,4:-0.784571811923;DBP:-0.794525402908;TGIF1:-0.79568445866;FOXP1:-0.860382199467;ATF6:-0.914866306225;MYFfamily:-0.951991327759;MZF1:-0.996218623853;PDX1:-1.11701586261;PATZ1:-1.16035173883;TLX2:-1.3349499084;FOXN1:-1.35844366919;POU5F1:-1.46672703371 | |||
|xref= | |||
|zenbu_report=https://fantom.gsc.riken.jp/zenbu/reports/#miRNA_expression_atlas_human;search_select_hide=table111:FF:12641-134G4;search_select_hide=table117:FF:12641-134G4 | |||
}} | }} |
Latest revision as of 18:41, 4 June 2020
Name: | Melanocyte, donor1 (MC+1) |
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Species: | Human (Homo sapiens) |
Library ID: | CNhs12816 |
Sample type: | time courses |
Genomic View: | UCSC |
RefEX: | Specific genes |
FANTOM CAT: | 1, 2, 3, 4, 5, 6, 7 |
CAGEd-oPOSSUM: | link |
ZENBU report : | link |
Additional information | ||||||||||||||||||||||||||||
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Sample information
RNA information
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CAGE Accession numbers | ||||||||||||||||||||||||||||||||||||||||||||||
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Download raw sequence, BAM & CTSS | ||||||||||||||
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Relative expression to median (log10)
Transcription factors with enriched expression in this sampleRanked list of transcription factor promoter expression in this sample relative to the median expression in the FANTOM5 collection is shown. Value is log10 transformed.
Co-expression clusters with enriched expression in this sampleRanked list of co-expression cluster expression in this sample relative to the median expression in the FANTOM5 collection is shown. Value is log10 transformed. <br>Analyst:NA <br><br>link to dataset.<br>data
Repeat families with enriched expression in this sample<b>Summary:</b>Ranked list of repeat family expression in this sample relative tothe median expression in the FANTOM5 collection is shown. Value is log10transformed.<br><b>Analyst:</b>NA<br><br>link to dataset.<br>data
TFBS(DNA)motifs over-represented in proximal region of promoters active in this sample
JASPAR motifs<b>Summary:</b>Association of JASPAR motif to the promoter expression in thissample. Pearson's correlation between the number of TFBSs estimated byusing the position-weight matrix for each promoter and its expression isexpressed as Z-score by taking the ones based on random position-weightmatrix, and the tail probability of the normal distribution correspondingto the Z-score is taken as the resulting P-value. Lower P-value indicatesmore (non-random) association of the motif to promoter expression<br><b>Analyst:</b> Michiel de Hoon <br><br><br>link to dataset.<br>data
library id: CNhs12816
FANTOM5 phase1 novel unique motifs<b>Summary:</b>Association of the 169 novel and unique motifs discovered in FANTOM5 phase1 in this sample. Among the de-novo motifs discovered by DMF, HOMER,ChIPMunk, and ScanAll, only novel motifs are selected after comparison with known motif sets, and their clustering based on MACRO-APE resulted in169 novel and unique motifs. Their association to the promoter expression is evaluated in the same way to the JASPAR motif above<br><b>Analyst:</b> Michiel de Hoon <br><br><br>link to dataset.<br>data
library id: CNhs12816
Novel motif | Logo | P-value |
---|---|---|
1 | 1 | 0.63 |
10 | 10 | 0.559 |
100 | 100 | 0.105 |
101 | 101 | 0.131 |
102 | 102 | 0.188 |
103 | 103 | 0.0407 |
104 | 104 | 0.508 |
105 | 105 | 0.0599 |
106 | 106 | 0.00513 |
107 | 107 | 0.0573 |
108 | 108 | 0.775 |
109 | 109 | 0.0387 |
11 | 11 | 0.872 |
110 | 110 | 0.0428 |
111 | 111 | 0.849 |
112 | 112 | 0.851 |
113 | 113 | 0.003 |
114 | 114 | 0.233 |
115 | 115 | 0.944 |
116 | 116 | 0.687 |
117 | 117 | 0.463 |
118 | 118 | 0.172 |
119 | 119 | 0.548 |
12 | 12 | 0.351 |
120 | 120 | 0.215 |
121 | 121 | 0.805 |
122 | 122 | 0.821 |
123 | 123 | 0.279 |
124 | 124 | 0.711 |
125 | 125 | 0.578 |
126 | 126 | 0.598 |
127 | 127 | 0.627 |
128 | 128 | 0.316 |
129 | 129 | 0.32 |
13 | 13 | 0.08 |
130 | 130 | 0.364 |
131 | 131 | 0.0262 |
132 | 132 | 0.499 |
133 | 133 | 0.555 |
134 | 134 | 0.875 |
135 | 135 | 0.736 |
136 | 136 | 0.00259 |
137 | 137 | 0.81 |
138 | 138 | 0.948 |
139 | 139 | 0.0068 |
14 | 14 | 0.456 |
140 | 140 | 0.349 |
141 | 141 | 0.4 |
142 | 142 | 0.911 |
143 | 143 | 0.578 |
144 | 144 | 0.558 |
145 | 145 | 0.597 |
146 | 146 | 0.224 |
147 | 147 | 0.428 |
148 | 148 | 0.163 |
149 | 149 | 0.228 |
15 | 15 | 0.881 |
150 | 150 | 0.867 |
151 | 151 | 0.568 |
152 | 152 | 0.394 |
153 | 153 | 0.137 |
154 | 154 | 0.143 |
155 | 155 | 0.828 |
156 | 156 | 0.943 |
157 | 157 | 0.68 |
158 | 158 | 0.11 |
159 | 159 | 0.371 |
16 | 16 | 0.462 |
160 | 160 | 0.318 |
161 | 161 | 0.934 |
162 | 162 | 0.606 |
163 | 163 | 0.478 |
164 | 164 | 0.883 |
165 | 165 | 0.263 |
166 | 166 | 0.15 |
167 | 167 | 0.946 |
168 | 168 | 0.748 |
169 | 169 | 0.825 |
17 | 17 | 0.82 |
18 | 18 | 0.403 |
19 | 19 | 0.613 |
2 | 2 | 0.465 |
20 | 20 | 0.259 |
21 | 21 | 0.558 |
22 | 22 | 0.541 |
23 | 23 | 0.133 |
24 | 24 | 0.919 |
25 | 25 | 0.438 |
26 | 26 | 0.582 |
27 | 27 | 0.368 |
28 | 28 | 0.412 |
29 | 29 | 0.0127 |
3 | 3 | 0.683 |
30 | 30 | 0.142 |
31 | 31 | 0.806 |
32 | 32 | 0.283 |
33 | 33 | 0.455 |
34 | 34 | 0.465 |
35 | 35 | 0.251 |
36 | 36 | 0.863 |
37 | 37 | 0.523 |
38 | 38 | 0.608 |
39 | 39 | 0.766 |
4 | 4 | 0.387 |
40 | 40 | 0.0909 |
41 | 41 | 0.989 |
42 | 42 | 0.147 |
43 | 43 | 0.693 |
44 | 44 | 0.0558 |
45 | 45 | 0.0753 |
46 | 46 | 0.706 |
47 | 47 | 0.778 |
48 | 48 | 0.497 |
49 | 49 | 0.45 |
5 | 5 | 0.45 |
50 | 50 | 0.804 |
51 | 51 | 0.876 |
52 | 52 | 0.149 |
53 | 53 | 0.0926 |
54 | 54 | 0.875 |
55 | 55 | 0.213 |
56 | 56 | 0.522 |
57 | 57 | 0.242 |
58 | 58 | 0.051 |
59 | 59 | 0.599 |
6 | 6 | 0.38 |
60 | 60 | 0.0975 |
61 | 61 | 0.775 |
62 | 62 | 0.033 |
63 | 63 | 0.936 |
64 | 64 | 0.751 |
65 | 65 | 0.865 |
66 | 66 | 0.037 |
67 | 67 | 0.228 |
68 | 68 | 0.384 |
69 | 69 | 0.936 |
7 | 7 | 0.634 |
70 | 70 | 0.341 |
71 | 71 | 0.971 |
72 | 72 | 0.251 |
73 | 73 | 0.398 |
74 | 74 | 0.556 |
75 | 75 | 0.614 |
76 | 76 | 0.0777 |
77 | 77 | 0.574 |
78 | 78 | 0.254 |
79 | 79 | 0.86 |
8 | 8 | 0.616 |
80 | 80 | 0.346 |
81 | 81 | 0.483 |
82 | 82 | 0.367 |
83 | 83 | 0.888 |
84 | 84 | 0.368 |
85 | 85 | 0.341 |
86 | 86 | 0.244 |
87 | 87 | 0.0127 |
88 | 88 | 0.668 |
89 | 89 | 0.425 |
9 | 9 | 0.519 |
90 | 90 | 0.224 |
91 | 91 | 0.255 |
92 | 92 | 0.012 |
93 | 93 | 0.0542 |
94 | 94 | 0.805 |
95 | 95 | 5.34884e-6 |
96 | 96 | 0.439 |
97 | 97 | 0.598 |
98 | 98 | 0.175 |
99 | 99 | 0.0804 |
de novo motifs identified by HOMER in promoters active in this sample<b>Summary:</b>The result of HOMER in this sample is shown.<br><b>Analyst:</b>NA <br>
library id: CNhs12816
FANTOM5 (FF) ontology
Direct parent terms
is_a relathionship
EFO:0002091 biological replicate
FF:0000730 human melanocyte (MC) sample
Ancestor terms (non development)<b>Summary:</b>Connected ontology terms with is_a, part_of or located_in relationship <br><b>Analyst:</b> Hideya Kawaji<br><br>link to source data<br>data
CL: Cell type
0000000 (cell), 0000000 (cell)
0000003 (native cell)
0000548 (animal cell)
0000075 (columnar/cuboidal epithelial cell)
0000066 (epithelial cell)
0002371 (somatic cell)
0000325 (stuff accumulating cell)
0000147 (pigment cell)
0000710 (neurecto-epithelial cell)
0000255 (eukaryotic cell)
0002077 (ecto-epithelial cell)
0000148 (melanocyte)
FF: FANTOM5
0000210 (human sample)
0000101 (sample by species)
0000001 (sample)
0000343 (control treatment sample)
0000350 (experimentally modified sample)
0000730 (human melanocyte (MC) sample)
Ancestor terms (development)<b>Summary:</b>Connected ontology terms with develops_from, derives_from or preceded_by relationship <br><b>Analyst:</b> Hideya Kawaji <br><br>link to source data<br>data
CL:0000133 (neurectodermal cell)
CL:0000221 (ectodermal cell)