FF:10638-108I8: Difference between revisions
From FANTOM5_SSTAR
(Created page with "{{f5samples
|id=FF:10638-108I8
|name=clear cell carcinoma cell line:JHOC-5, biol_rep1
|sample_id=10638
|rna_tube_id=108I8
|rna_box=108
|rna_position=I8
|sample_cell_lot...") |
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{{f5samples | {{f5samples | ||
| | |DRA_sample_Accession=CAGE@SAMD00005922 | ||
| | |accession_numbers=CAGE;DRX007860;DRR008732;DRZ000157;DRZ001542;DRZ011507;DRZ012892 | ||
|ancestors_in_anatomy_facet= | |ancestors_in_anatomy_facet= | ||
|ancestors_in_disease_facet=DOID: | |ancestors_in_cell_lineage_facet=CL:0000000,CL:0000003,CL:0000548,CL:0000066,CL:0000255 | ||
| | |ancestors_in_disease_facet=DOID:4,DOID:0050686,DOID:162,DOID:14566,DOID:0050687,DOID:193,DOID:305,DOID:120,DOID:299,DOID:4468 | ||
|ancestors_in_ff_facet=FF:0000102,FF:0000003,FF:0000210,FF:0000101,FF:0000001,FF:0100297,FF:0101120,FF:0100167,FF:0102787 | |||
|comment= | |||
|created_by= | |||
|creation_date= | |||
|data_phase=2 | |||
|datafreeze_phase=2 | |||
|def= | |||
|expression_enrichment_score=chr2:114036488..114036504,-!p1@PAX8!2.42!262.27!PAX8;;chr17:36105042..36105060,-!p1@HNF1B!2.00!99.59!HNF1B;;chr12:66218255..66218304,+!p3@HMGA2!1.52!83.77!HMGA2;;chr8:55370487..55370503,+!p1@SOX17!1.50!30.81!SOX17;;chr1:201979743..201979762,+!p1@ELF3!1.50!30.38!ELF3;;chr12:66218183..66218209,+!p4@HMGA2!1.38!43.68!HMGA2;;chr12:66218152..66218174,+!p10@HMGA2!1.37!23.84!HMGA2;;chr20:31350184..31350200,+!p1@DNMT3B!1.29!37.77!DNMT3B;;chr12:66218378..66218401,+!p6@HMGA2!1.29!28.70!HMGA2;;chr12:66218212..66218244,+!p5@HMGA2!1.27!25.32!HMGA2;;chr1:201979703..201979721,+!p2@ELF3!1.26!17.09!ELF3;;chr2:113982635..113982648,-!p8@PAX8!1.25!16.67!PAX8;;chr17:53342311..53342400,+!p1@HLF!1.24!18.78!HLF;;chr12:66218003..66218018,+!p9@HMGA2!1.21!18.57!HMGA2;;chr7:57509877..57509895,+!p1@ZNF716!1.21!15.19!ZNF716;;chr6:10412600..10412637,-!p1@TFAP2A!1.20!24.48!TFAP2A;;chr12:19556960..19556982,+!p10@AEBP2!1.19!14.56!AEBP2;;chr12:66218573..66218596,+!p7@HMGA2!1.18!21.31!HMGA2;;chr12:66218598..66218645,+!p2@HMGA2!1.17!63.09!HMGA2;;chr12:66357214..66357233,+!p13@HMGA2!1.14!12.66!HMGA2;;chr3:111314186..111314204,-!p1@ZBED2!1.09!11.39!ZBED2;;chrX:2418949..2419024,-!p1@DHRSX,p1@ZBED1!1.09!11.39!ZBED1;;chr2:46524897..46524911,+!p2@EPAS1!1.08!30.81!EPAS1;;chr12:66218420..66218439,+!p12@HMGA2!1.08!10.97!HMGA2;;chr6:10415276..10415341,-!p2@TFAP2A!1.05!12.66!TFAP2A;;chr12:66358080..66358094,+!p15@HMGA2!1.03!9.71!HMGA2;;chr3:69811858..69811881,+!p5@MITF!1.02!9.49!MITF;;chr17:36104873..36104903,-!p3@HNF1B!0.99!8.86!HNF1B;;chr11:31832658..31832681,-!p1@PAX6!0.98!8.65!PAX6;;chr12:66218836..66218888,+!p1@HMGA2!0.97!80.39!HMGA2;;chr12:66218443..66218461,+!p8@HMGA2!0.96!10.55!HMGA2;;chr17:36105074..36105086,-!p2@HNF1B!0.96!8.02!HNF1B;;chr6:10412392..10412409,-!p4@TFAP2A!0.94!8.86!TFAP2A;;chr12:19556998..19557013,+!p6@AEBP2!0.91!7.17!AEBP2;;chr11:65667884..65667895,-!p2@FOSL1!0.90!27.85!FOSL1;;chr8:28347737..28347785,-!p1@FBXO16,p2@ZNF395!0.89!14.98!ZNF395;;chr9:100615499..100615519,+!p1@FOXE1!0.89!6.75!FOXE1;;chr3:32023232..32023273,+!p1@ZNF860!0.88!9.71!ZNF860;;chr19:45971246..45971265,+!p1@FOSB!0.85!120.48!FOSB;;chr7:28725740..28725778,+!p1@CREB5!0.85!58.24!CREB5;;chr7:27153454..27153469,-!p2@HOXA3!0.83!5.70!HOXA3;;chr7:27169801..27169844,-!p2@HOXA4!0.83!5.70!HOXA4;;chr17:46682321..46682362,-!p1@HOXB6!0.83!5.70!HOXB6;;chr12:77459306..77459365,-!p1@E2F7!0.82!75.12!E2F7;;chr14:62213758..62213774,+!p8@HIF1A!0.81!7.17!HIF1A;;chr6:28048343..28048354,+!p1@ZNF165!0.81!5.49!ZNF165;;chr17:41623692..41623715,-!p1@ETV4!0.80!24.69!ETV4;;chr7:28448965..28448994,+!p2@CREB5!0.80!20.04!CREB5;;chr14:62213827..62213853,+!p6@HIF1A!0.80!7.81!HIF1A;;chr3:141747459..141747475,-!p1@TFDP2!0.78!45.58!TFDP2;;chr7:26191809..26191890,+!p1@NFE2L3!0.78!27.01!NFE2L3;;chr12:66357317..66357328,+!p19@HMGA2!0.78!5.06!HMGA2;;chr14:62203595..62203676,+!p4@HIF1A!0.77!9.71!HIF1A;;chr1:59249645..59249656,-!p4@JUN!0.75!12.45!JUN;;chr8:76319876..76319926,+!p1@HNF4G!0.75!4.64!HNF4G;;chr2:176994408..176994492,+!p1@HOXD8!0.75!4.64!HOXD8;;chr3:69812798..69812824,+!p8@MITF!0.75!4.64!MITF;;chr3:101546827..101546847,+!p2@NFKBIZ!0.74!6.54!NFKBIZ;;chr3:101568349..101568365,+!p1@NFKBIZ!0.73!258.05!NFKBIZ;;chr17:41277372..41277418,-!p1@BRCA1!0.73!17.51!BRCA1;;chr1:8934931..8934947,-!p4@ENO1!0.73!15.61!ENO1;;chr2:46524878..46524891,+!p3@EPAS1!0.73!8.23!EPAS1;;chr17:46622229..46622257,-!p6@HOXB2!0.73!5.27!HOXB2;;chr3:69915369..69915381,+!p4@MITF!0.73!4.43!MITF;;chr13:79177703..79177729,-!p2@POU4F1!0.73!4.43!POU4F1;;chr15:67357924..67357952,+!p2@SMAD3!0.72!31.86!SMAD3;;chr7:27135591..27135658,-!p1@HOXA1!0.72!8.65!HOXA1;;chr5:170736243..170736279,+!p1@TLX3!0.72!4.22!TLX3;;chr3:69811882..69811898,+!p6@MITF!0.72!4.22!MITF;;chr17:46688334..46688385,-!p1@HOXB7!0.70!6.12!HOXB7;;chr5:170736216..170736238,+!p2@TLX3!0.70!4.01!TLX3;;chr19:22235279..22235301,+!p1@ZNF257!0.69!8.02!ZNF257;;chr10:104154246..104154347,+!p3@NFKB2!0.68!26.16!NFKB2;;chr16:51185172..51185197,-!p1@SALL1!0.68!3.80!SALL1;;chr2:176969228..176969260,+!p1@HOXD11!0.68!3.80!HOXD11;;chr3:69915385..69915438,+!p3@MITF!0.68!3.80!MITF;;chr8:77593474..77593612,+!p1@ZFHX4!0.67!17.51!ZFHX4;;chr17:41622834..41622883,-!p6@ETV4!0.67!4.64!ETV4;;chr3:157823517..157823562,-!p1@SHOX2!0.67!4.01!SHOX2;;chr6:44233252..44233296,-!p1@NFKBIE!0.66!41.14!NFKBIE;;chr5:72744594..72744609,-!p1@FOXD1!0.66!18.78!FOXD1;;chr14:35872453..35872485,-!p2@NFKBIA!0.66!9.71!NFKBIA;;chr19:48774586..48774670,+!p1@ZNF114!0.66!4.64!ZNF114;;chr12:85673977..85674015,+!p1@ALX1!0.66!3.59!ALX1;;chr18:55102598..55102623,+!p1@ONECUT2!0.66!3.59!ONECUT2;;chr5:172662197..172662216,-!p1@NKX2-5!0.66!3.59!NKX2-5;;chr2:191906489..191906517,-!p6@STAT4!0.66!3.59!STAT4;;chr16:29818160..29818188,+!p6@MAZ!0.65!18.78!MAZ;;chr16:1429627..1429662,-!p2@UNKL!0.65!11.39!UNKL;;chr22:42269885..42269899,+!p4@SREBF2!0.65!5.49!SREBF2;;chr5:72743793..72743855,-!p4@FOXD1!0.65!4.22!FOXD1;;chr10:104155480..104155534,+!p2@NFKB2!0.64!25.32!NFKB2;;chr22:38597987..38598021,+!p2@MAFF!0.64!24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| |||
|fonse_cell_line=FF:0101120 | |fonse_cell_line=FF:0101120 | ||
|fonse_cell_line_closure=FF:0101120 | |fonse_cell_line_closure=FF:0101120 | ||
Line 67: | Line 39: | ||
|fonse_treatment= | |fonse_treatment= | ||
|fonse_treatment_closure= | |fonse_treatment_closure= | ||
|has_quality= | |||
|hg19bam=http://fantom.gsc.riken.jp/5/datafiles/latest/basic/human.cell_line.hCAGE/clear%2520cell%2520carcinoma%2520cell%2520line%253aJHOC-5.CNhs11745.10638-108I8.hg19.nobarcode.bam | |||
|hg19ctss=http://fantom.gsc.riken.jp/5/datafiles/latest/basic/human.cell_line.hCAGE/clear%2520cell%2520carcinoma%2520cell%2520line%253aJHOC-5.CNhs11745.10638-108I8.hg19.ctss.bed.gz | |||
|hg19fasta=http://fantom.gsc.riken.jp/5/datafiles/latest/basic/human.cell_line.hCAGE/clear%2520cell%2520carcinoma%2520cell%2520line%253aJHOC-5.CNhs11745.10638-108I8.hg19.nobarcode.rdna.fa.gz | |||
|hg38bam=http://fantom.gsc.riken.jp/5/datafiles/reprocessed/hg38_v2/basic/human.cell_line.hCAGE/clear%2520cell%2520carcinoma%2520cell%2520line%253aJHOC-5.CNhs11745.10638-108I8.hg38.nobarcode.bam | |||
|hg38ctss=http://fantom.gsc.riken.jp/5/datafiles/reprocessed/hg38_v2/basic/human.cell_line.hCAGE/clear%2520cell%2520carcinoma%2520cell%2520line%253aJHOC-5.CNhs11745.10638-108I8.hg38.nobarcode.ctss.bed.gz | |||
|id=FF:10638-108I8 | |||
|is_a=EFO:0002091;;FF:0000210;;FF:0102787 | |||
|is_obsolete= | |||
|library_id=CNhs11745 | |||
|library_id_phase_based=2:CNhs11745 | |||
|microRNAs= | |||
|microRNAs_nn= | |||
|microRNAs_nonnovel_cage=http://fantom.gsc.riken.jp/5/suppl/De_Rie_et_al_2017/vis_viewer/#/human#cage;sample;10638 | |||
|microRNAs_novel_cage=http://fantom.gsc.riken.jp/5/suppl/De_Rie_et_al_2017/vis_viewer_novel/#/human#cage;sample;10638 | |||
|name=clear cell carcinoma cell line:JHOC-5 | |||
|namespace=FANTOM5 | |||
|part_of= | |||
|profile_cagescan=,,, | |||
|profile_hcage=CNhs11745,LSID819,release009,COMPLETED | |||
|profile_rnaseq= | |||
|profile_srnaseq=,,, | |||
|refex=http://refex.dbcls.jp/genelist.php?lang | |||
|repeat_enrich_byfamily=0,0,0.214713381346818,0,0,0.0831434490344895,0,0.48075620986505,0,0.154593464487547,0.484236561029049,0,0,0,0.0831434490344895,0,0,0,0,0,0,0,0.0831434490344895,0,0.36794308107579,0,0,0,0,0,0.563567728613694,0,0,0.132802503583949,0,0,0,0,0,0,0,0,0,0,0.0831434490344895,0,0.199777195881364,0.264587705798395,0,0,0,0,0,0,0,0.414497721552036,0,0,0,0,0,0,0,0.584064728945837,0,0,-0.0142001781786075,0,0,0,0,0,0,0,0,0.0831434490344895,0,0,0,0,0,0,0,0,0.165769089558758,0,0,0,0,0,0,-0.0311291817245495,0.106492320262126,0,0,-0.0798383316910913,0.0494356430162399,0,0,0,0,-0.0148919022032169,0.364844302870958,0,0,0,0.0831434490344895,0,0,0.152898414163168,0,0,0,0.461092224465682,0,0,0,0,0,0,-0.096373593922461,0.152898414163168,0,0,0.113956884777906,0.272666482570084,0,0,0.25517295079693,0,0,0 | |||
|repeat_enrich_byname=0,0,0,0,-0.0148919022032169,0,0,0,0,0,0.212984640524252,0,0,0,0,0,-0.247178875285564,0.0415717245172448,0.0471798726722089,-0.0603716934889824,0.0415717245172448,0,0.09177075883099,0,0.212984640524252,0,0,0,0,0.0831434490344895,0,0,-0.128119866952565,0,-0.0504125515893149,0.0415717245172448,0,0,0,-0.0186252810838506,-0.305472230898407,0,0.0227037544224407,-0.0683442610773682,0,0,0,0,-0.117342255171156,0,0.341366122004199,0.183038925039394,0,-0.334354317229937,0.0274309522533075,0,0,0,-0.587505763195718,-0.470361074322787,0,0,0.208982960689001,0.102771541622766,0,0,-0.391044581551635,0,-0.000298851346146267,0.0293362358188048,0,0.111582419298656,0,0,0,0,0,0.0831434490344895,0,0.152898414163168,0.46224560579794,0,0,-0.0574934668214365,0.165769089558758,0.00117465271254235,0.0831434490344895,0.265759093362812,0,-0.265916958801624,0,0.0720392175299132,0.199930751740516,0.00780893219867873,0,-0.189318628070855,0,0.397358116260798,-0.100688293863599,-0.281405565159068,-0.236999068785263,-0.147401849371139,-0.0370833053866791,0.103296058601792,0.101728898239499,0.0530762927306486,0.0119959343248272,-0.475063897474903,-0.0571384258489827,-0.464033287276267,0.0254450039580498,0,0,0,-0.0137139830670245,0,-0.0963401703496642,-0.277130073952522,0.0478394107895755,-0.143701875031112,-0.26798241187939,-0.0407387979239055,0.453539638050211,0.1085315163227,-0.244451812372343,0,-0.22461050933175,0,0,-0.0587576127885164,0.00652510719448979,-0.572927466583071,-0.402841532654428,0,-0.270992821286729,-0.0683442610773682,0,-0.244351098265033,-0.242049135165553,0.152898414163168,0.0831434490344895,-0.184853599727511,0,0,-0.111880100372614,0,0,-0.00741618197064087,0.361581089241414,-0.0198709210312933,0,-0.165339480650676,0.0101645393964457,0.0308940980131998,0,-0.031971098590855,-0.0628664484229047,0,-0.139735390433068,0,0.0846386479990577,0.373778736012966,0.0479939441852487,0.0988712860324799,0.0246966222226643,0.0522839320619183,-0.00863280847961434,-0.0798383316910913,0.166166824198448,-0.101364614532639,-0.0881268324752877,0,-0.0311291817245495,-0.679498131621524,-0.0654301031545308,-0.106028258211738,0,-0.116370590395605,0,0.0725342926942563,0,-0.0679925558595996,-0.54043375147324,0.38658753547419,-0.0547597758555447,0,-0.0326161032847851,-0.704987488739484,0,0.0404254078654689,-0.0640221573205895,0.521266091424217,-0.150367083334639,0.179729518817158,-0.0635863830852189,0.357943978933751,0,-0.00732429255200717,0,0,-0.0499256863881761,0.257281648473338,0,0.202871835040265,0.202770660593875,0.285194253009826,0.0369273407282342,0,0,0.180176572062152,0,0,0.219948846236846,-0.0636048451378017,0.115093228617311,0.0124327518760559,-0.0268275037317087,0.662932958944397,0,0.0831434490344895,0.463546473986261,0,-0.109834657175477,0,0.0831434490344895,-0.0969828824356555,0,0,0,0,0.0653673551543445,0,0,0,0,0,0,0,0.359244707626577,0.193184508853653,0,0.0361842462103122,0,0,0,0.0831434490344895,0,0,0,0,-0.0646403728877671,0.0360594622856584,0.142741677686391,0.629512082766743,0,0,0,0.050035690809337,0.152021117747875,0.152898414163168,0.0811219340266198,0,0,0,0,-0.0861409897892114,0,0,0.5272855614446,0.0831434490344895,0.155254183470588,-0.0714460330006003,0,0,0,0.646545156707427,0,0,0,0,-0.221590045877605,0,0,0,0,-0.33253045443959,0.31234175159706,0,0.323629611082512,-0.304791744698742,0.553406979728257,0,0,-0.261347131789888,0,0,-0.0707932277279318,0,0.0831434490344895,0.0206469485711278,0,0,0,0,0,0,0.0984952686376937,0,0,0,0,0.573216907697083,0.152898414163168,0.984568744665421,0,0,0,0,-0.415230515656181,0.173535036704301,0.223068963017621,0,0,0,0,0,0,0.0939149085199258,0.10545571874196,0,0,0.0415717245172448,0.0831434490344895,0,0.0831434490344895,0,0,0.354450970391634,0.461092224465682,0,0,0,0,0.584064728945837,0,0.0831434490344895,0,0.429426762693637,0.655663341020648,0,0,-0.0643774916692625,0,0,0,0,0,0,0,0,0,0,0,0,0,0.0295793281277205,0.177013897414559,0,0.0831434490344895,0,0,0,0,0,0.154593464487547,0,0.312809781037449,0,0,-0.113884373708977,0,0,0,0.468420522907927,0,0.48075620986505,0.0831434490344895,0.0831434490344895,0,0,0,0.0831434490344895,0.076449207081584,0.0415717245172448,0,0,0,0,0,0,0,0,0,0,0,0,0,-0.105294971919285,0,-0.28720751597291,-0.0568589461625992,0,0,0.0137504904858219,0,0,0,0,0,0,0.0751518962335985,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0.152898414163168,0,0,0,0,0,0,-0.0066639283233122,0,0,0,0,0,0,0,0.563567728613694,0.152898414163168,0,0.147339057143005,0,0,0,0,0.312809781037449,0,0.257499353130984,-0.206771192741564,0.0343652672592691,0,0,0,0.178468525117854,0,0,-0.0379413734288656,0,-0.0667773874189013,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0.36794308107579,0,0,0,0,0,0,0,0,0,0,0,0,0.0415717245172448,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0.212984640524252,0.0415717245172448,0,0,0,0,0,0,0.114052681503954,0.212984640524252,0,0.0831434490344895,0,0,0,0,0,0,0,0,0,0,0,0,0,0.0415717245172448,0,0,0,0,0,0.27523921157396,0,0,0,0.249159376140896,0,0,0,0,0,0,0.312809781037449,0,0.0831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| |||
|rna_box=108 | |||
|rna_catalog_number= | |||
|rna_concentration=0.58552 | |||
|rna_extraction_protocol=OP-RNA-extraction-totalRNA-miRNeasy_Mini-v1.0 | |||
|rna_lot_number= | |||
|rna_od260/230=1.96 | |||
|rna_od260/280=2.09 | |||
|rna_position=I8 | |||
|rna_rin= | |||
|rna_sample_type=total RNA | |||
|rna_tube_id=108I8 | |||
|rna_weight_ug=27.51944 | |||
|sample_age=54 | |||
|sample_category=cell lines | |||
|sample_cell_catalog=RCB1520 | |||
|sample_cell_line=JHOC-5 | |||
|sample_cell_lot= | |||
|sample_cell_type=unclassifiable | |||
|sample_collaboration=Yukio Nakamura (RIKEN BRC) | |||
|sample_company=RIKEN Bioresource centre | |||
|sample_description= | |||
|sample_dev_stage= | |||
|sample_disease=clear cell carcinoma | |||
|sample_donor(cell lot)= | |||
|sample_ethnicity=J | |||
|sample_experimental_condition= | |||
|sample_gostat=GO:0044464;cell part;0!GO:0005622;intracellular;0!GO:0044424;intracellular part;3.5942060158385e-254!GO:0043226;organelle;4.51403254554761e-206!GO:0043229;intracellular organelle;1.71825087957831e-205!GO:0043231;intracellular membrane-bound organelle;3.93553811806255e-205!GO:0043227;membrane-bound organelle;4.79095515375571e-205!GO:0005737;cytoplasm;7.5383361347478e-190!GO:0044422;organelle part;1.59276365976319e-164!GO:0044446;intracellular organelle part;6.51348261952887e-163!GO:0044444;cytoplasmic part;1.91079961132775e-129!GO:0032991;macromolecular complex;1.12307714637691e-114!GO:0044237;cellular metabolic process;5.05675819328449e-92!GO:0030529;ribonucleoprotein complex;1.22154979143878e-90!GO:0044238;primary metabolic process;1.47094223938112e-90!GO:0044428;nuclear part;1.27498380830813e-86!GO:0005634;nucleus;1.33835430319376e-85!GO:0043170;macromolecule metabolic process;7.78157220452578e-83!GO:0043233;organelle lumen;1.58077019570014e-81!GO:0031974;membrane-enclosed lumen;1.58077019570014e-81!GO:0005739;mitochondrion;8.96505960202521e-77!GO:0003723;RNA binding;3.18067024315221e-74!GO:0005515;protein binding;1.0296230513004e-69!GO:0043234;protein complex;2.00767929808052e-60!GO:0006396;RNA processing;2.41332595725739e-55!GO:0031090;organelle membrane;4.38900280612075e-54!GO:0019538;protein metabolic process;2.7913150617643e-53!GO:0005840;ribosome;1.53804242617768e-52!GO:0016043;cellular component organization and biogenesis;3.32343455496543e-52!GO:0006412;translation;2.31204303148438e-51!GO:0031981;nuclear lumen;1.69516542573258e-50!GO:0044429;mitochondrial part;3.48498241884862e-50!GO:0043283;biopolymer metabolic process;1.20059637132503e-49!GO:0044267;cellular protein metabolic process;2.32056594871559e-47!GO:0044260;cellular macromolecule metabolic process;2.7015227483357e-47!GO:0033036;macromolecule localization;1.03733942176181e-46!GO:0015031;protein transport;1.06187945144433e-46!GO:0031967;organelle envelope;6.61336536190901e-46!GO:0003735;structural constituent of ribosome;7.72956466159714e-46!GO:0031975;envelope;1.68670375385386e-45!GO:0009058;biosynthetic process;3.15309761095438e-45!GO:0044249;cellular biosynthetic process;9.49660372322914e-44!GO:0043228;non-membrane-bound organelle;9.68556498173541e-44!GO:0043232;intracellular non-membrane-bound organelle;9.68556498173541e-44!GO:0008104;protein localization;5.41798887253481e-43!GO:0045184;establishment of protein localization;5.07078496006465e-42!GO:0016071;mRNA metabolic process;2.43114725233862e-41!GO:0008380;RNA splicing;2.62761148486338e-41!GO:0006139;nucleobase, nucleoside, nucleotide and nucleic acid metabolic process;4.56742771087699e-41!GO:0046907;intracellular transport;1.43461740421676e-39!GO:0033279;ribosomal subunit;5.1133291209441e-39!GO:0006996;organelle organization and biogenesis;7.5339031634596e-39!GO:0005829;cytosol;1.49501199577197e-38!GO:0009059;macromolecule biosynthetic process;5.88008314651654e-38!GO:0010467;gene expression;1.78732027492945e-37!GO:0006397;mRNA processing;7.14009977803082e-37!GO:0006259;DNA metabolic process;1.94211025588269e-36!GO:0065003;macromolecular complex assembly;6.83447512162318e-35!GO:0022613;ribonucleoprotein complex biogenesis and assembly;9.13517574285631e-34!GO:0006886;intracellular protein transport;6.89342538437174e-33!GO:0007049;cell cycle;2.64843579411191e-32!GO:0005740;mitochondrial envelope;1.93462521512798e-31!GO:0005654;nucleoplasm;2.90368446766794e-31!GO:0022607;cellular component assembly;3.93593023380809e-30!GO:0000166;nucleotide binding;1.12355223089823e-29!GO:0019866;organelle inner membrane;1.32167854317551e-29!GO:0031966;mitochondrial membrane;2.86289583654593e-29!GO:0005681;spliceosome;3.31935009640743e-29!GO:0005743;mitochondrial inner membrane;3.08833449753193e-27!GO:0051649;establishment of cellular localization;5.3697673139879e-27!GO:0051641;cellular localization;7.58611494368324e-27!GO:0005830;cytosolic ribosome (sensu Eukaryota);2.10928881349599e-25!GO:0044451;nucleoplasm part;4.87543034145577e-25!GO:0006974;response to DNA damage stimulus;8.73208074217267e-25!GO:0000278;mitotic cell cycle;2.46261878751535e-24!GO:0022402;cell cycle process;3.94219654323966e-24!GO:0012505;endomembrane system;2.51334814256072e-23!GO:0016462;pyrophosphatase activity;5.68295028455337e-23!GO:0016818;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides;6.98697262184177e-23!GO:0006119;oxidative phosphorylation;7.40337795907423e-23!GO:0016817;hydrolase activity, acting on acid anhydrides;1.05009465826145e-22!GO:0017111;nucleoside-triphosphatase activity;1.82577236421379e-22!GO:0031980;mitochondrial lumen;2.07410700540898e-22!GO:0005759;mitochondrial matrix;2.07410700540898e-22!GO:0044455;mitochondrial membrane part;2.97985830378151e-22!GO:0003676;nucleic acid binding;1.05334825914309e-21!GO:0005694;chromosome;1.85586991434894e-21!GO:0006457;protein folding;1.88311834856367e-21!GO:0005730;nucleolus;2.77231377732465e-21!GO:0044445;cytosolic part;3.02718633577203e-21!GO:0032553;ribonucleotide binding;3.48550905777391e-21!GO:0032555;purine ribonucleotide binding;3.48550905777391e-21!GO:0016874;ligase activity;6.50745921199135e-21!GO:0015935;small ribosomal subunit;1.18388142694807e-20!GO:0017076;purine nucleotide binding;1.5436138672841e-20!GO:0000087;M phase of mitotic cell cycle;1.85451591680553e-20!GO:0007067;mitosis;2.70439179856117e-20!GO:0006281;DNA repair;3.74904701725488e-20!GO:0006512;ubiquitin cycle;5.10236476205361e-20!GO:0044265;cellular macromolecule catabolic process;5.6245557570127e-20!GO:0043285;biopolymer catabolic process;1.40821516077104e-19!GO:0015934;large ribosomal subunit;1.62474614761988e-19!GO:0022618;protein-RNA complex assembly;1.76189480440895e-19!GO:0044427;chromosomal part;1.81436794919668e-19!GO:0009057;macromolecule catabolic process;7.70413401276625e-19!GO:0022403;cell cycle phase;7.72003844979298e-19!GO:0005524;ATP binding;1.38317416254408e-18!GO:0051301;cell division;1.49506650580253e-18!GO:0051603;proteolysis involved in cellular protein catabolic process;1.75925922132049e-18!GO:0032559;adenyl ribonucleotide binding;1.99174735726323e-18!GO:0019941;modification-dependent protein catabolic process;2.5659356992526e-18!GO:0043632;modification-dependent macromolecule catabolic process;2.5659356992526e-18!GO:0006511;ubiquitin-dependent protein catabolic process;2.6938811123141e-18!GO:0005761;mitochondrial ribosome;3.42762631649782e-18!GO:0000313;organellar ribosome;3.42762631649782e-18!GO:0000502;proteasome complex (sensu Eukaryota);3.5682739498978e-18!GO:0044257;cellular protein catabolic process;4.14483353250196e-18!GO:0005783;endoplasmic reticulum;6.23764082470205e-18!GO:0030554;adenyl nucleotide binding;1.27030399335979e-17!GO:0051186;cofactor metabolic process;1.47035295282906e-17!GO:0043412;biopolymer modification;2.48933627507609e-17!GO:0030163;protein catabolic process;3.41444156303565e-17!GO:0016655;oxidoreductase activity, acting on NADH or NADPH, quinone or similar compound as acceptor;3.50959293461234e-17!GO:0048770;pigment granule;6.27858181921638e-17!GO:0042470;melanosome;6.27858181921638e-17!GO:0008134;transcription factor binding;6.27858181921638e-17!GO:0044248;cellular catabolic process;6.37657824382023e-17!GO:0005746;mitochondrial respiratory chain;7.77225151017495e-17!GO:0000279;M phase;8.90265897017271e-17!GO:0006605;protein targeting;9.18757408381679e-17!GO:0006260;DNA replication;1.00041964025406e-16!GO:0044432;endoplasmic reticulum part;1.18140340043021e-16!GO:0031965;nuclear membrane;3.29277417263521e-16!GO:0016070;RNA metabolic process;7.76516206615534e-16!GO:0005635;nuclear envelope;1.23737395171787e-15!GO:0009719;response to endogenous stimulus;1.27396062805376e-15!GO:0051276;chromosome organization and biogenesis;1.53082629718459e-15!GO:0050136;NADH dehydrogenase (quinone) activity;1.63457127720954e-15!GO:0003954;NADH dehydrogenase activity;1.63457127720954e-15!GO:0008137;NADH dehydrogenase (ubiquinone) activity;1.63457127720954e-15!GO:0012501;programmed cell death;1.95923244319596e-15!GO:0000398;nuclear mRNA splicing, via spliceosome;2.5376714029772e-15!GO:0000375;RNA splicing, via transesterification reactions;2.5376714029772e-15!GO:0000377;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile;2.5376714029772e-15!GO:0006915;apoptosis;4.34960112778627e-15!GO:0006464;protein modification process;5.31473798836162e-15!GO:0042254;ribosome biogenesis and assembly;5.34439517186748e-15!GO:0044453;nuclear membrane part;6.371769899423e-15!GO:0016887;ATPase activity;7.75015514370998e-15!GO:0008135;translation factor activity, nucleic acid binding;1.23481127387736e-14!GO:0042623;ATPase activity, coupled;1.42303460539948e-14!GO:0008219;cell death;4.55662808898652e-14!GO:0016265;death;4.55662808898652e-14!GO:0051082;unfolded protein binding;6.4390500122273e-14!GO:0048193;Golgi vesicle transport;7.12191740322074e-14!GO:0043687;post-translational protein modification;1.50370201953386e-13!GO:0005843;cytosolic small ribosomal subunit (sensu Eukaryota);2.14207865148012e-13!GO:0042175;nuclear envelope-endoplasmic reticulum network;2.25678313482272e-13!GO:0030964;NADH dehydrogenase complex (quinone);2.44243920260541e-13!GO:0045271;respiratory chain complex I;2.44243920260541e-13!GO:0005747;mitochondrial respiratory chain complex I;2.44243920260541e-13!GO:0006732;coenzyme metabolic process;3.90424962996111e-13!GO:0042775;organelle ATP synthesis coupled electron transport;3.94051276856391e-13!GO:0042773;ATP synthesis coupled electron transport;3.94051276856391e-13!GO:0016192;vesicle-mediated transport;4.25362580797109e-13!GO:0006399;tRNA metabolic process;6.02882040753725e-13!GO:0005789;endoplasmic reticulum membrane;6.73118576198009e-13!GO:0006120;mitochondrial electron transport, NADH to ubiquinone;6.77706403209536e-13!GO:0005842;cytosolic large ribosomal subunit (sensu Eukaryota);1.49171754007505e-12!GO:0016651;oxidoreductase activity, acting on NADH or NADPH;2.02394745283617e-12!GO:0000074;regulation of progression through cell cycle;3.02272012480764e-12!GO:0009259;ribonucleotide metabolic process;3.8546021371224e-12!GO:0005643;nuclear pore;3.87669211883436e-12!GO:0005794;Golgi apparatus;3.93229852178507e-12!GO:0051726;regulation of cell cycle;4.08687492443755e-12!GO:0006413;translational initiation;8.47234948772434e-12!GO:0004386;helicase activity;9.77225513879993e-12!GO:0003743;translation initiation factor activity;1.06151017651017e-11!GO:0015630;microtubule cytoskeleton;1.21717856497044e-11!GO:0006325;establishment and/or maintenance of chromatin architecture;1.28550352502972e-11!GO:0016604;nuclear body;2.0812993220157e-11!GO:0009055;electron carrier activity;2.33185564946e-11!GO:0006163;purine nucleotide metabolic process;2.34278971085103e-11!GO:0009056;catabolic process;2.93770741509223e-11!GO:0006913;nucleocytoplasmic transport;2.93809415816803e-11!GO:0006446;regulation of translational initiation;3.88175897682344e-11!GO:0009260;ribonucleotide biosynthetic process;4.5760060722525e-11!GO:0006323;DNA packaging;4.62476956353818e-11!GO:0008639;small protein conjugating enzyme activity;4.8255872428597e-11!GO:0003712;transcription cofactor activity;6.82873716232807e-11!GO:0006164;purine nucleotide biosynthetic process;6.90106935264572e-11!GO:0051169;nuclear transport;7.80390413941218e-11!GO:0004842;ubiquitin-protein ligase activity;9.92749796950522e-11!GO:0065002;intracellular protein transport across a membrane;1.02387169946619e-10!GO:0009150;purine ribonucleotide metabolic process;1.06499702430331e-10!GO:0046961;hydrogen ion transporting ATPase activity, rotational mechanism;1.23852629025195e-10!GO:0006461;protein complex assembly;2.10276497959083e-10!GO:0019787;small conjugating protein ligase activity;2.50604742663637e-10!GO:0043067;regulation of programmed cell death;2.737158428498e-10!GO:0007005;mitochondrion organization and biogenesis;2.737158428498e-10!GO:0006403;RNA localization;2.76735183265505e-10!GO:0009152;purine ribonucleotide biosynthetic process;3.07903268381294e-10!GO:0000785;chromatin;3.71092480214683e-10!GO:0042981;regulation of apoptosis;3.93210306822439e-10!GO:0016876;ligase activity, forming aminoacyl-tRNA and related compounds;4.55527157733919e-10!GO:0004812;aminoacyl-tRNA ligase activity;4.55527157733919e-10!GO:0016875;ligase activity, forming carbon-oxygen bonds;4.55527157733919e-10!GO:0008026;ATP-dependent helicase activity;4.5766437895861e-10!GO:0050657;nucleic acid transport;4.82933783987105e-10!GO:0051236;establishment of RNA localization;4.82933783987105e-10!GO:0050658;RNA transport;4.82933783987105e-10!GO:0051188;cofactor biosynthetic process;4.92931433603155e-10!GO:0006364;rRNA processing;5.72327789106568e-10!GO:0016072;rRNA metabolic process;6.4682196408951e-10!GO:0016740;transferase activity;6.5058295749018e-10!GO:0046930;pore complex;6.65258682870774e-10!GO:0016879;ligase activity, forming carbon-nitrogen bonds;6.6658894346697e-10!GO:0017038;protein import;8.10970398303061e-10!GO:0043038;amino acid activation;8.10970398303061e-10!GO:0006418;tRNA aminoacylation for protein translation;8.10970398303061e-10!GO:0043039;tRNA aminoacylation;8.10970398303061e-10!GO:0046933;hydrogen ion transporting ATP synthase activity, rotational mechanism;9.0280090414453e-10!GO:0009199;ribonucleoside triphosphate metabolic process;9.99439869388672e-10!GO:0043069;negative regulation of programmed cell death;1.25502312285846e-09!GO:0055086;nucleobase, nucleoside and nucleotide metabolic process;1.31456133453157e-09!GO:0009141;nucleoside triphosphate metabolic process;1.54926499199332e-09!GO:0005768;endosome;1.96759727119064e-09!GO:0009205;purine ribonucleoside triphosphate metabolic process;2.34125242385196e-09!GO:0009144;purine nucleoside triphosphate metabolic process;2.34125242385196e-09!GO:0065004;protein-DNA complex assembly;2.34125242385196e-09!GO:0015931;nucleobase, nucleoside, nucleotide and nucleic acid transport;3.92016166771676e-09!GO:0043066;negative regulation of apoptosis;4.07653789212108e-09!GO:0009142;nucleoside triphosphate biosynthetic process;4.7489630326621e-09!GO:0009201;ribonucleoside triphosphate biosynthetic process;4.7489630326621e-09!GO:0015986;ATP synthesis coupled proton transport;4.7489630326621e-09!GO:0015985;energy coupled proton transport, down electrochemical gradient;4.7489630326621e-09!GO:0016607;nuclear speck;5.73331257979615e-09!GO:0006333;chromatin assembly or disassembly;5.9703079340761e-09!GO:0006366;transcription from RNA polymerase II promoter;6.96006925939054e-09!GO:0030532;small nuclear ribonucleoprotein complex;8.86499652325865e-09!GO:0005793;ER-Golgi intermediate compartment;8.90879190528556e-09!GO:0016881;acid-amino acid ligase activity;9.05086934864232e-09!GO:0016779;nucleotidyltransferase activity;9.07558214358995e-09!GO:0008565;protein transporter activity;9.49018585706507e-09!GO:0009206;purine ribonucleoside triphosphate biosynthetic process;1.12526101925422e-08!GO:0009145;purine nucleoside triphosphate biosynthetic process;1.12526101925422e-08!GO:0043566;structure-specific DNA binding;1.22589829166925e-08!GO:0046034;ATP metabolic process;1.45569601735807e-08!GO:0032446;protein modification by small protein conjugation;1.8232186395252e-08!GO:0009117;nucleotide metabolic process;1.86263280765641e-08!GO:0009060;aerobic respiration;1.89676520075543e-08!GO:0016787;hydrolase activity;2.3891125642919e-08!GO:0051028;mRNA transport;2.72768713506432e-08!GO:0016567;protein ubiquitination;2.92861843433323e-08!GO:0009108;coenzyme biosynthetic process;2.93686827887504e-08!GO:0005839;proteasome core complex (sensu Eukaryota);3.14269002513826e-08!GO:0000775;chromosome, pericentric region;3.74534443894275e-08!GO:0016591;DNA-directed RNA polymerase II, holoenzyme;4.25802322835477e-08!GO:0006261;DNA-dependent DNA replication;4.88327973300685e-08!GO:0006754;ATP biosynthetic process;5.78136899723584e-08!GO:0006753;nucleoside phosphate metabolic process;5.78136899723584e-08!GO:0048523;negative regulation of cellular process;5.90826065665928e-08!GO:0005667;transcription factor complex;7.3394330957977e-08!GO:0015078;hydrogen ion transmembrane transporter activity;7.70142777649683e-08!GO:0006793;phosphorus metabolic process;7.95066839371328e-08!GO:0006796;phosphate metabolic process;7.95066839371328e-08!GO:0045333;cellular respiration;1.04693117409814e-07!GO:0006916;anti-apoptosis;1.26178223535802e-07!GO:0004298;threonine endopeptidase activity;1.31501746811921e-07!GO:0005819;spindle;1.38693548941983e-07!GO:0016772;transferase activity, transferring phosphorus-containing groups;1.79015044054597e-07!GO:0019829;cation-transporting ATPase activity;1.95865708042591e-07!GO:0003697;single-stranded DNA binding;2.29015951815187e-07!GO:0006888;ER to Golgi vesicle-mediated transport;2.48733375886809e-07!GO:0000245;spliceosome assembly;2.52555751652906e-07!GO:0016469;proton-transporting two-sector ATPase complex;3.3087302856693e-07!GO:0030120;vesicle coat;4.94779875702393e-07!GO:0030662;coated vesicle membrane;4.94779875702393e-07!GO:0045259;proton-transporting ATP synthase complex;5.1857583717385e-07!GO:0051246;regulation of protein metabolic process;5.4579629824472e-07!GO:0005815;microtubule organizing center;5.52276211447635e-07!GO:0016568;chromatin modification;6.46732067330739e-07!GO:0007249;I-kappaB kinase/NF-kappaB cascade;6.70593581176405e-07!GO:0006334;nucleosome assembly;6.88925475603127e-07!GO:0005813;centrosome;7.1059490635499e-07!GO:0006752;group transfer coenzyme metabolic process;7.37072437729507e-07!GO:0048519;negative regulation of biological process;1.14972486594232e-06!GO:0006606;protein import into nucleus;1.25465574454932e-06!GO:0048475;coated membrane;1.44618572252911e-06!GO:0030117;membrane coat;1.44618572252911e-06!GO:0006099;tricarboxylic acid cycle;1.56575941423604e-06!GO:0046356;acetyl-CoA catabolic process;1.56575941423604e-06!GO:0016310;phosphorylation;1.61643311116054e-06!GO:0043623;cellular protein complex assembly;2.07449234881327e-06!GO:0005770;late endosome;2.07449234881327e-06!GO:0051170;nuclear import;2.10150926923648e-06!GO:0005657;replication fork;2.18705657117447e-06!GO:0050794;regulation of cellular process;2.44192248392853e-06!GO:0003899;DNA-directed RNA polymerase activity;2.49831799399732e-06!GO:0006084;acetyl-CoA metabolic process;2.71135440674728e-06!GO:0005762;mitochondrial large ribosomal subunit;2.71135440674728e-06!GO:0000315;organellar large ribosomal subunit;2.71135440674728e-06!GO:0043123;positive regulation of I-kappaB kinase/NF-kappaB cascade;2.84867114196145e-06!GO:0051187;cofactor catabolic process;3.33310011628916e-06!GO:0044440;endosomal part;3.33310011628916e-06!GO:0010008;endosome membrane;3.33310011628916e-06!GO:0031497;chromatin assembly;3.44767541368894e-06!GO:0043122;regulation of I-kappaB kinase/NF-kappaB cascade;3.83380730112031e-06!GO:0003924;GTPase activity;3.85254512280758e-06!GO:0000314;organellar small ribosomal subunit;4.39695554175959e-06!GO:0005763;mitochondrial small ribosomal subunit;4.39695554175959e-06!GO:0008094;DNA-dependent ATPase activity;4.44990686103062e-06!GO:0016491;oxidoreductase activity;5.85015588231693e-06!GO:0031202;RNA splicing factor activity, transesterification mechanism;6.01174934011229e-06!GO:0051329;interphase of mitotic cell cycle;6.10990037585224e-06!GO:0008654;phospholipid biosynthetic process;6.6433632323723e-06!GO:0007051;spindle organization and biogenesis;7.10056815528604e-06!GO:0000151;ubiquitin ligase complex;7.1048927261587e-06!GO:0007088;regulation of mitosis;7.54041540298222e-06!GO:0015077;monovalent inorganic cation transmembrane transporter activity;7.835069016477e-06!GO:0003724;RNA helicase activity;7.97230922270895e-06!GO:0003690;double-stranded DNA binding;8.65538017530435e-06!GO:0044431;Golgi apparatus part;1.04427773218308e-05!GO:0006613;cotranslational protein targeting to membrane;1.17078124382746e-05!GO:0016563;transcription activator activity;1.26482422695159e-05!GO:0051427;hormone receptor binding;1.41575693914439e-05!GO:0051325;interphase;1.52832428836235e-05!GO:0009109;coenzyme catabolic process;1.96438807944318e-05!GO:0000075;cell cycle checkpoint;2.13047634230129e-05!GO:0003714;transcription corepressor activity;2.15612133060246e-05!GO:0031324;negative regulation of cellular metabolic process;3.0468137069792e-05!GO:0005874;microtubule;3.10652729429438e-05!GO:0035257;nuclear hormone receptor binding;3.21198629289353e-05!GO:0009165;nucleotide biosynthetic process;3.41121312586802e-05!GO:0045786;negative regulation of progression through cell cycle;3.87162827549151e-05!GO:0003713;transcription coactivator activity;4.00987433488012e-05!GO:0006302;double-strand break repair;4.5919660675722e-05!GO:0007010;cytoskeleton organization and biogenesis;4.69720411378439e-05!GO:0016564;transcription repressor activity;5.42113827651373e-05!GO:0005769;early endosome;6.39125326296363e-05!GO:0006839;mitochondrial transport;6.43243168496481e-05!GO:0042625;ATPase activity, coupled to transmembrane movement of ions;7.06287875368795e-05!GO:0006091;generation of precursor metabolites and energy;7.66899844221903e-05!GO:0065009;regulation of a molecular function;7.87632070314888e-05!GO:0045454;cell redox homeostasis;8.11336571064248e-05!GO:0043021;ribonucleoprotein binding;8.58653429627681e-05!GO:0005525;GTP binding;8.6897131337899e-05!GO:0005788;endoplasmic reticulum lumen;8.7954795648972e-05!GO:0031988;membrane-bound vesicle;9.84047021174936e-05!GO:0000139;Golgi membrane;9.87843612704338e-05!GO:0008033;tRNA processing;0.000105196897979137!GO:0031968;organelle outer membrane;0.000107807781016578!GO:0016023;cytoplasmic membrane-bound vesicle;0.000111028012745284!GO:0016126;sterol biosynthetic process;0.000111028012745284!GO:0007243;protein kinase cascade;0.00011181618980727!GO:0019899;enzyme binding;0.000117355847599746!GO:0009892;negative regulation of metabolic process;0.000119000381660252!GO:0005753;mitochondrial proton-transporting ATP synthase complex;0.000119906689150145!GO:0045934;negative regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process;0.000125334893115035!GO:0030530;heterogeneous nuclear ribonucleoprotein complex;0.000128712717413702!GO:0031252;leading edge;0.000132104391778235!GO:0016853;isomerase activity;0.000132744589322003!GO:0048471;perinuclear region of cytoplasm;0.000135239219677264!GO:0006612;protein targeting to membrane;0.000151458796727114!GO:0019867;outer membrane;0.000152565857271942!GO:0006357;regulation of transcription from RNA polymerase II promoter;0.000152565857271942!GO:0051168;nuclear export;0.000153958003948874!GO:0015405;P-P-bond-hydrolysis-driven transmembrane transporter activity;0.000176178613106434!GO:0015399;primary active transmembrane transporter activity;0.000176178613106434!GO:0005798;Golgi-associated vesicle;0.000194056459187687!GO:0008610;lipid biosynthetic process;0.000194056459187687!GO:0019752;carboxylic acid metabolic process;0.000195242547152579!GO:0003684;damaged DNA binding;0.000197822139929014!GO:0008186;RNA-dependent ATPase activity;0.000230724515567078!GO:0006082;organic acid metabolic process;0.000238077120347834!GO:0008250;oligosaccharyl transferase complex;0.000238077120347834!GO:0006950;response to stress;0.000244559211297234!GO:0005048;signal sequence binding;0.000248929739966584!GO:0006695;cholesterol biosynthetic process;0.000252356735843758!GO:0000776;kinetochore;0.000254211385031566!GO:0033116;ER-Golgi intermediate compartment membrane;0.000264274689607917!GO:0043681;protein import into mitochondrion;0.00027382353121943!GO:0007006;mitochondrial membrane organization and biogenesis;0.000291124985206793!GO:0004576;oligosaccharyl transferase activity;0.000297947784056813!GO:0000226;microtubule cytoskeleton organization and biogenesis;0.000308821875668407!GO:0048522;positive regulation of cellular process;0.000317022991044283!GO:0015980;energy derivation by oxidation of organic compounds;0.000320306383009205!GO:0000079;regulation of cyclin-dependent protein kinase activity;0.000325629695942888!GO:0006626;protein targeting to mitochondrion;0.000333012517502069!GO:0046483;heterocycle metabolic process;0.000342140460691815!GO:0051052;regulation of DNA metabolic process;0.000384624621513456!GO:0007059;chromosome segregation;0.000399996032401295!GO:0008637;apoptotic mitochondrial changes;0.000402326508942036!GO:0003755;peptidyl-prolyl cis-trans isomerase activity;0.000410277324240025!GO:0004579;dolichyl-diphosphooligosaccharide-protein glycotransferase activity;0.000435960412733421!GO:0048468;cell development;0.000438904046370906!GO:0006520;amino acid metabolic process;0.000438904046370906!GO:0033178;proton-transporting two-sector ATPase complex, catalytic domain;0.000493421065790677!GO:0004674;protein serine/threonine kinase activity;0.000496381162885178!GO:0007093;mitotic cell cycle checkpoint;0.000499102967615107!GO:0003678;DNA helicase activity;0.000503837034655231!GO:0016859;cis-trans isomerase activity;0.000532459414154709!GO:0005741;mitochondrial outer membrane;0.000562534627339757!GO:0016481;negative regulation of transcription;0.000608317744814115!GO:0006414;translational elongation;0.000608600918307482!GO:0051920;peroxiredoxin activity;0.000618362351455839!GO:0046467;membrane lipid biosynthetic process;0.000632477445567043!GO:0015631;tubulin binding;0.000633765545249222!GO:0016197;endosome transport;0.000636285474806007!GO:0030880;RNA polymerase complex;0.000681195235893595!GO:0030036;actin cytoskeleton organization and biogenesis;0.000683557408141764!GO:0000786;nucleosome;0.000683557408141764!GO:0007017;microtubule-based process;0.000687216637329595!GO:0004004;ATP-dependent RNA helicase activity;0.000687226203102649!GO:0005852;eukaryotic translation initiation factor 3 complex;0.000708747226015589!GO:0003729;mRNA binding;0.000709658777206532!GO:0016363;nuclear matrix;0.000739590781070127!GO:0044452;nucleolar part;0.000739590781070127!GO:0019843;rRNA binding;0.000763637859162383!GO:0005885;Arp2/3 protein complex;0.000771467216592479!GO:0045261;proton-transporting ATP synthase complex, catalytic core F(1);0.000798918420335704!GO:0006383;transcription from RNA polymerase III promoter;0.000817214019257821!GO:0032561;guanyl ribonucleotide binding;0.000830616823521283!GO:0019001;guanyl nucleotide binding;0.000830616823521283!GO:0016272;prefoldin complex;0.000838955777150569!GO:0006352;transcription initiation;0.000861119214837789!GO:0005838;proteasome regulatory particle (sensu Eukaryota);0.00088642692853801!GO:0006310;DNA recombination;0.000910718660753547!GO:0019205;nucleobase, nucleoside, nucleotide kinase activity;0.000911760658847027!GO:0005773;vacuole;0.000981184682528198!GO:0016679;oxidoreductase activity, acting on diphenols and related substances as donors;0.000981184682528198!GO:0016681;oxidoreductase activity, acting on diphenols and related substances as donors, cytochrome as acceptor;0.000981184682528198!GO:0008121;ubiquinol-cytochrome-c reductase activity;0.000981184682528198!GO:0005684;U2-dependent spliceosome;0.00102574918840498!GO:0048487;beta-tubulin binding;0.0010350911837395!GO:0045263;proton-transporting ATP synthase complex, coupling factor F(o);0.0010350911837395!GO:0033177;proton-transporting two-sector ATPase complex, proton-transporting domain;0.0010350911837395!GO:0030867;rough endoplasmic reticulum membrane;0.0010564993410135!GO:0005905;coated pit;0.0010564993410135!GO:0018196;peptidyl-asparagine modification;0.00106144882103588!GO:0018279;protein amino acid N-linked glycosylation via asparagine;0.00106144882103588!GO:0003682;chromatin binding;0.00112205902328979!GO:0008632;apoptotic program;0.00113069174508893!GO:0005876;spindle microtubule;0.00114927494614575!GO:0006402;mRNA catabolic process;0.00123968416190409!GO:0030118;clathrin coat;0.00125800083585475!GO:0042802;identical protein binding;0.00129626617835908!GO:0006891;intra-Golgi vesicle-mediated transport;0.00136900674276034!GO:0032508;DNA duplex unwinding;0.00140832192821649!GO:0032392;DNA geometric change;0.00140832192821649!GO:0001836;release of cytochrome c from mitochondria;0.00140832192821649!GO:0016251;general RNA polymerase II transcription factor activity;0.00151596722376376!GO:0006401;RNA catabolic process;0.00152975974385615!GO:0055029;nuclear DNA-directed RNA polymerase complex;0.00154530952754029!GO:0000428;DNA-directed RNA polymerase complex;0.00154530952754029!GO:0007264;small GTPase mediated signal transduction;0.00164558954182828!GO:0008168;methyltransferase activity;0.0016523464459469!GO:0043492;ATPase activity, coupled to movement of substances;0.00166680031129337!GO:0045045;secretory pathway;0.00170461614730458!GO:0051789;response to protein stimulus;0.00177995024763847!GO:0006986;response to unfolded protein;0.00177995024763847!GO:0016044;membrane organization and biogenesis;0.00182146531519201!GO:0000059;protein import into nucleus, docking;0.00187475397878352!GO:0016741;transferase activity, transferring one-carbon groups;0.00192942531555123!GO:0050789;regulation of biological process;0.00195050725894167!GO:0042626;ATPase activity, coupled to transmembrane movement of substances;0.00195648027595387!GO:0000287;magnesium ion binding;0.00202727452809643!GO:0030658;transport vesicle membrane;0.002044138108073!GO:0031982;vesicle;0.00211575690644793!GO:0046474;glycerophospholipid biosynthetic process;0.00212213805437424!GO:0031902;late endosome membrane;0.00224631911925663!GO:0005637;nuclear inner membrane;0.0023766949413971!GO:0048500;signal recognition particle;0.0023881944874957!GO:0046489;phosphoinositide biosynthetic process;0.00254652954499217!GO:0016820;hydrolase activity, acting on acid anhydrides, catalyzing transmembrane movement of substances;0.00264881124196011!GO:0051087;chaperone binding;0.00267025632440011!GO:0045893;positive regulation of transcription, DNA-dependent;0.00271724310625225!GO:0051540;metal cluster binding;0.00271724310625225!GO:0051536;iron-sulfur cluster binding;0.00271724310625225!GO:0051098;regulation of binding;0.00277924588142848!GO:0043596;nuclear replication fork;0.00278127803145649!GO:0006268;DNA unwinding during replication;0.00284232206647542!GO:0030659;cytoplasmic vesicle membrane;0.00286665477535731!GO:0006220;pyrimidine nucleotide metabolic process;0.0028717553059212!GO:0031410;cytoplasmic vesicle;0.00289444654507379!GO:0006270;DNA replication initiation;0.00317674481216957!GO:0030521;androgen receptor signaling pathway;0.00351178675938571!GO:0006890;retrograde vesicle-mediated transport, Golgi to ER;0.00361315490433557!GO:0007052;mitotic spindle organization and biogenesis;0.00361315490433557!GO:0000323;lytic vacuole;0.00363273036588041!GO:0005764;lysosome;0.00363273036588041!GO:0051101;regulation of DNA binding;0.00363273036588041!GO:0050662;coenzyme binding;0.00375398932171179!GO:0045935;positive regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process;0.00383649477319803!GO:0030660;Golgi-associated vesicle membrane;0.00409398944169418!GO:0042770;DNA damage response, signal transduction;0.00423696582491952!GO:0006289;nucleotide-excision repair;0.00424702242791583!GO:0006284;base-excision repair;0.00429225071418861!GO:0008092;cytoskeletal protein binding;0.00433972378922201!GO:0006144;purine base metabolic process;0.00434893529280788!GO:0008234;cysteine-type peptidase activity;0.00439513236323235!GO:0000228;nuclear chromosome;0.00439513236323235!GO:0035258;steroid hormone receptor binding;0.00446527048311467!GO:0030029;actin filament-based process;0.0047916382130288!GO:0043065;positive regulation of apoptosis;0.00483739119140405!GO:0022415;viral reproductive process;0.00483739119140405!GO:0051252;regulation of RNA metabolic process;0.00489586000294227!GO:0032200;telomere organization and biogenesis;0.00489586000294227!GO:0000723;telomere maintenance;0.00489586000294227!GO:0016627;oxidoreductase activity, acting on the CH-CH group of donors;0.00496264081071964!GO:0008757;S-adenosylmethionine-dependent methyltransferase activity;0.00502677379959025!GO:0016765;transferase activity, transferring alkyl or aryl (other than methyl) groups;0.00504959274842712!GO:0022890;inorganic cation transmembrane transporter activity;0.00507238314389537!GO:0045941;positive regulation of transcription;0.00516358970468347!GO:0007050;cell cycle arrest;0.00530162765727733!GO:0003711;transcription elongation regulator activity;0.00530162765727733!GO:0008312;7S RNA binding;0.00540929227255597!GO:0031072;heat shock protein binding;0.00540929227255597!GO:0043624;cellular protein complex disassembly;0.00541113383942222!GO:0006611;protein export from nucleus;0.00594706214950516!GO:0043068;positive regulation of programmed cell death;0.00613761462069347!GO:0009112;nucleobase metabolic process;0.00616193838093616!GO:0030132;clathrin coat of coated pit;0.00621028844897741!GO:0008022;protein C-terminus binding;0.00624160675727213!GO:0050790;regulation of catalytic activity;0.00630437691783249!GO:0006778;porphyrin metabolic process;0.00659370053925517!GO:0033013;tetrapyrrole metabolic process;0.00659370053925517!GO:0005786;signal recognition particle, endoplasmic reticulum targeting;0.00659370053925517!GO:0016862;intramolecular oxidoreductase activity, interconverting keto- and enol-groups;0.00662778088834645!GO:0044262;cellular carbohydrate metabolic process;0.00668466997528847!GO:0016676;oxidoreductase activity, acting on heme group of donors, oxygen as acceptor;0.00668650657412228!GO:0015002;heme-copper terminal oxidase activity;0.00668650657412228!GO:0016675;oxidoreductase activity, acting on heme group of donors;0.00668650657412228!GO:0004129;cytochrome-c oxidase activity;0.00668650657412228!GO:0044433;cytoplasmic vesicle part;0.00670554123219807!GO:0046822;regulation of nucleocytoplasmic transport;0.00676468627928776!GO:0006614;SRP-dependent cotranslational protein targeting to membrane;0.00680438546543399!GO:0045047;protein targeting to ER;0.00680438546543399!GO:0000082;G1/S transition of mitotic cell cycle;0.00681175030105495!GO:0007021;tubulin folding;0.00698769127662423!GO:0000922;spindle pole;0.00705618220841434!GO:0000049;tRNA binding;0.00709020793937602!GO:0043022;ribosome binding;0.00713112544519023!GO:0019206;nucleoside kinase activity;0.00729344782845827!GO:0046983;protein dimerization activity;0.0074640937895442!GO:0006497;protein amino acid lipidation;0.0074640937895442!GO:0030125;clathrin vesicle coat;0.00748503969104077!GO:0030665;clathrin coated vesicle membrane;0.00748503969104077!GO:0006672;ceramide metabolic process;0.00768877729986865!GO:0043414;biopolymer methylation;0.00768877729986865!GO:0051539;4 iron, 4 sulfur cluster binding;0.00789473714944243!GO:0043130;ubiquitin binding;0.00790853020636774!GO:0032182;small conjugating protein binding;0.00790853020636774!GO:0030134;ER to Golgi transport vesicle;0.00803318609720951!GO:0043488;regulation of mRNA stability;0.00809766232747725!GO:0043487;regulation of RNA stability;0.00809766232747725!GO:0001726;ruffle;0.00835264325766569!GO:0000792;heterochromatin;0.00882165361396828!GO:0030133;transport vesicle;0.00882233530593615!GO:0046519;sphingoid metabolic process;0.00906929185029908!GO:0005791;rough endoplasmic reticulum;0.00929985438641211!GO:0016301;kinase activity;0.00929985438641211!GO:0006818;hydrogen transport;0.0093969437357299!GO:0015992;proton transport;0.00970218905639104!GO:0006595;polyamine metabolic process;0.00997575005903832!GO:0032259;methylation;0.0100263525487122!GO:0000725;recombinational repair;0.0101819012233743!GO:0000724;double-strand break repair via homologous recombination;0.0101819012233743!GO:0043433;negative regulation of transcription factor activity;0.0102444248528032!GO:0046966;thyroid hormone receptor binding;0.0103450468359527!GO:0008139;nuclear localization sequence binding;0.0103556208824179!GO:0008017;microtubule binding;0.0106773040174717!GO:0012506;vesicle membrane;0.0108245336068067!GO:0003746;translation elongation factor activity;0.010827313434273!GO:0006275;regulation of DNA replication;0.0108520789980454!GO:0031124;mRNA 3'-end processing;0.0110949776536461!GO:0008180;signalosome;0.0113082997031429!GO:0000209;protein polyubiquitination;0.0114868520754774!GO:0005832;chaperonin-containing T-complex;0.0115976955292287!GO:0007242;intracellular signaling cascade;0.0117365721722214!GO:0006376;mRNA splice site selection;0.0117374297064724!GO:0000389;nuclear mRNA 3'-splice site recognition;0.0117374297064724!GO:0030119;AP-type membrane coat adaptor complex;0.0117518935120281!GO:0016584;nucleosome positioning;0.0117518935120281!GO:0005665;DNA-directed RNA polymerase II, core complex;0.0117570017915872!GO:0051287;NAD binding;0.0120520980689355!GO:0030663;COPI coated vesicle membrane;0.0120520980689355!GO:0030126;COPI vesicle coat;0.0120520980689355!GO:0006519;amino acid and derivative metabolic process;0.0120520980689355!GO:0017166;vinculin binding;0.0120960162505228!GO:0005758;mitochondrial intermembrane space;0.0122111786395491!GO:0000781;chromosome, telomeric region;0.0122675454430884!GO:0009116;nucleoside metabolic process;0.0123319437283344!GO:0006730;one-carbon compound metabolic process;0.0123664845464749!GO:0008629;induction of apoptosis by intracellular signals;0.0129099869433192!GO:0043161;proteasomal ubiquitin-dependent protein catabolic process;0.0130439003529443!GO:0030330;DNA damage response, signal transduction by p53 class mediator;0.0131205887857566!GO:0009451;RNA modification;0.0131205887857566!GO:0009967;positive regulation of signal transduction;0.0131316676428091!GO:0030127;COPII vesicle coat;0.0132568266660992!GO:0012507;ER to Golgi transport vesicle membrane;0.0132568266660992!GO:0000096;sulfur amino acid metabolic process;0.0132581760108262!GO:0032984;macromolecular complex disassembly;0.0133182724564673!GO:0043601;nuclear replisome;0.013610311078461!GO:0030894;replisome;0.013610311078461!GO:0006378;mRNA polyadenylation;0.0138368837369403!GO:0009303;rRNA transcription;0.014311808504999!GO:0016790;thiolester hydrolase activity;0.0144363838335581!GO:0016407;acetyltransferase activity;0.0146303284970441!GO:0004518;nuclease activity;0.0148630383216155!GO:0016281;eukaryotic translation initiation factor 4F complex;0.0149953117326205!GO:0044454;nuclear chromosome part;0.0150271190051047!GO:0048037;cofactor binding;0.0151110260837661!GO:0006767;water-soluble vitamin metabolic process;0.0151641016908217!GO:0043241;protein complex disassembly;0.0151641016908217!GO:0007034;vacuolar transport;0.0151841074059028!GO:0004527;exonuclease activity;0.0153938961190169!GO:0004003;ATP-dependent DNA helicase activity;0.0162349971039123!GO:0008538;proteasome activator activity;0.016290626978774!GO:0006518;peptide metabolic process;0.0163052473380788!GO:0043284;biopolymer biosynthetic process;0.0163052473380788!GO:0016667;oxidoreductase activity, acting on sulfur group of donors;0.016436871362594!GO:0009262;deoxyribonucleotide metabolic process;0.0165062001699596!GO:0030131;clathrin adaptor complex;0.0170601149016473!GO:0043189;H4/H2A histone acetyltransferase complex;0.0177395743353226!GO:0000086;G2/M transition of mitotic cell cycle;0.0178717563289303!GO:0007004;telomere maintenance via telomerase;0.0182884306621071!GO:0030137;COPI-coated vesicle;0.0184382921307429!GO:0006506;GPI anchor biosynthetic process;0.0185926148483682!GO:0050681;androgen receptor binding;0.0186456488503922!GO:0016408;C-acyltransferase activity;0.0187134963723095!GO:0043154;negative regulation of caspase activity;0.0187758938821785!GO:0016791;phosphoric monoester hydrolase activity;0.0193207336724598!GO:0046982;protein heterodimerization activity;0.0199993843998277!GO:0050178;phenylpyruvate tautomerase activity;0.0203157742820032!GO:0031570;DNA integrity checkpoint;0.0205590122451753!GO:0008287;protein serine/threonine phosphatase complex;0.0206431225948208!GO:0030176;integral to endoplasmic reticulum membrane;0.0206543128406467!GO:0042168;heme metabolic process;0.0207445992943511!GO:0000307;cyclin-dependent protein kinase holoenzyme complex;0.020835904186503!GO:0042158;lipoprotein biosynthetic process;0.0209089588653273!GO:0005669;transcription factor TFIID complex;0.0210441635543117!GO:0006405;RNA export from nucleus;0.0210692583615314!GO:0006221;pyrimidine nucleotide biosynthetic process;0.0213320434774579!GO:0008415;acyltransferase activity;0.0215457058276619!GO:0042393;histone binding;0.02166840901437!GO:0000123;histone acetyltransferase complex;0.0223324390997756!GO:0006740;NADPH regeneration;0.0223324390997756!GO:0006098;pentose-phosphate shunt;0.0223324390997756!GO:0004680;casein kinase activity;0.0223549193320929!GO:0051338;regulation of transferase activity;0.0224931921982585!GO:0022411;cellular component disassembly;0.0224931921982585!GO:0003756;protein disulfide isomerase activity;0.0224931921982585!GO:0016864;intramolecular oxidoreductase activity, transposing S-S bonds;0.0224931921982585!GO:0007030;Golgi organization and biogenesis;0.0225499977965963!GO:0019079;viral genome replication;0.0227370488479962!GO:0031577;spindle checkpoint;0.0231577104683347!GO:0008299;isoprenoid biosynthetic process;0.02325811075366!GO:0000339;RNA cap binding;0.0235038857649371!GO:0005869;dynactin complex;0.023643682213112!GO:0033673;negative regulation of kinase activity;0.023643682213112!GO:0006469;negative regulation of protein kinase activity;0.023643682213112!GO:0035267;NuA4 histone acetyltransferase complex;0.0237261833048514!GO:0031625;ubiquitin protein ligase binding;0.0239306484763672!GO:0005996;monosaccharide metabolic process;0.0241227769848256!GO:0006892;post-Golgi vesicle-mediated transport;0.0241227769848256!GO:0031970;organelle envelope lumen;0.0241696210343755!GO:0006417;regulation of translation;0.0245367938385539!GO:0006505;GPI anchor metabolic process;0.024776430782689!GO:0007007;inner mitochondrial membrane organization and biogenesis;0.0248536035391625!GO:0019318;hexose metabolic process;0.0249742348472969!GO:0000122;negative regulation of transcription from RNA polymerase II promoter;0.0252044521085551!GO:0019222;regulation of metabolic process;0.0253754011813345!GO:0016311;dephosphorylation;0.0257612724351367!GO:0008047;enzyme activator activity;0.0257915442584076!GO:0043549;regulation of kinase activity;0.0258455618495478!GO:0051881;regulation of mitochondrial membrane potential;0.0258803735685253!GO:0031901;early endosome membrane;0.026038630763157!GO:0000910;cytokinesis;0.0261269846552406!GO:0016747;transferase activity, transferring groups other than amino-acyl groups;0.0261269846552406!GO:0030518;steroid hormone receptor signaling pathway;0.0261269846552406!GO:0032981;mitochondrial respiratory chain complex I assembly;0.0261269846552406!GO:0010257;NADH dehydrogenase complex assembly;0.0261269846552406!GO:0033108;mitochondrial respiratory chain complex assembly;0.0261269846552406!GO:0000184;mRNA catabolic process, nonsense-mediated decay;0.0261694178288327!GO:0042769;DNA damage response, detection of DNA damage;0.0261776314247668!GO:0007265;Ras protein signal transduction;0.0265450972572856!GO:0051348;negative regulation of transferase activity;0.0266506367862377!GO:0005850;eukaryotic translation initiation factor 2 complex;0.0268695230900132!GO:0030384;phosphoinositide metabolic process;0.0268695230900132!GO:0045892;negative regulation of transcription, DNA-dependent;0.027261426709106!GO:0006650;glycerophospholipid metabolic process;0.0277493523666998!GO:0048518;positive regulation of biological process;0.0277493523666998!GO:0016746;transferase activity, transferring acyl groups;0.0278119784115168!GO:0008601;protein phosphatase type 2A regulator activity;0.0283540536316279!GO:0031529;ruffle organization and biogenesis;0.0287201792223147!GO:0016780;phosphotransferase activity, for other substituted phosphate groups;0.0290122466427873!GO:0005784;translocon complex;0.02908497048095!GO:0032940;secretion by cell;0.0294429794331816!GO:0008625;induction of apoptosis via death domain receptors;0.0294746206426456!GO:0007041;lysosomal transport;0.0297676641711833!GO:0003887;DNA-directed DNA polymerase activity;0.0302095044876614!GO:0016776;phosphotransferase activity, phosphate group as acceptor;0.0304932127321929!GO:0007040;lysosome organization and biogenesis;0.0310165399093468!GO:0006779;porphyrin biosynthetic process;0.0310509910777397!GO:0033014;tetrapyrrole biosynthetic process;0.0310509910777397!GO:0009124;nucleoside monophosphate biosynthetic process;0.0317681114934308!GO:0009123;nucleoside monophosphate metabolic process;0.0317681114934308!GO:0000819;sister chromatid segregation;0.0317707653233236!GO:0050811;GABA receptor binding;0.0318260367065763!GO:0016125;sterol metabolic process;0.0320026512177025!GO:0019783;small conjugating protein-specific protease activity;0.0329938952152888!GO:0045859;regulation of protein kinase activity;0.0334152540727987!GO:0003923;GPI-anchor transamidase activity;0.0337685872605772!GO:0016255;attachment of GPI anchor to protein;0.0337685872605772!GO:0042765;GPI-anchor transamidase complex;0.0337685872605772!GO:0006278;RNA-dependent DNA replication;0.0340509178111995!GO:0000070;mitotic sister chromatid segregation;0.0343182128868353!GO:0031123;RNA 3'-end processing;0.0345760393604975!GO:0044450;microtubule organizing center part;0.0346068370509982!GO:0006007;glucose catabolic process;0.0347652975814655!GO:0005881;cytoplasmic microtubule;0.0349189775171441!GO:0000152;nuclear ubiquitin ligase complex;0.0354457137230036!GO:0000159;protein phosphatase type 2A complex;0.0354457137230036!GO:0006100;tricarboxylic acid cycle intermediate metabolic process;0.0356327022078639!GO:0005853;eukaryotic translation elongation factor 1 complex;0.0357638267946311!GO:0004532;exoribonuclease activity;0.0360364021950363!GO:0016896;exoribonuclease activity, producing 5'-phosphomonoesters;0.0360364021950363!GO:0006118;electron transport;0.0360433673697051!GO:0030027;lamellipodium;0.036428074390502!GO:0004843;ubiquitin-specific protease activity;0.0367693550228207!GO:0051656;establishment of organelle localization;0.0367693550228207!GO:0030031;cell projection biogenesis;0.0368216383137635!GO:0005521;lamin binding;0.0371334410461959!GO:0016615;malate dehydrogenase activity;0.0379074295372269!GO:0000178;exosome (RNase complex);0.0379074295372269!GO:0031371;ubiquitin conjugating enzyme complex;0.0380332893341385!GO:0032507;maintenance of cellular protein localization;0.0388290738276018!GO:0006807;nitrogen compound metabolic process;0.0394009570033171!GO:0030496;midbody;0.0394060695384289!GO:0006338;chromatin remodeling;0.0407974434192106!GO:0046426;negative regulation of JAK-STAT cascade;0.0412897887098437!GO:0008537;proteasome activator complex;0.0416113004906789!GO:0006360;transcription from RNA polymerase I promoter;0.0419612467757912!GO:0006367;transcription initiation from RNA polymerase II promoter;0.0420288305178237!GO:0006733;oxidoreduction coenzyme metabolic process;0.0424394273256814!GO:0044438;microbody part;0.0427520163735578!GO:0044439;peroxisomal part;0.0427520163735578!GO:0051223;regulation of protein transport;0.0429753291364935!GO:0046365;monosaccharide catabolic process;0.0429753291364935!GO:0005663;DNA replication factor C complex;0.043309332002345!GO:0006984;ER-nuclear signaling pathway;0.0433323357550541!GO:0051059;NF-kappaB binding;0.0437110743823683!GO:0000118;histone deacetylase complex;0.0443574365677591!GO:0016417;S-acyltransferase activity;0.0459064946749471!GO:0016773;phosphotransferase activity, alcohol group as acceptor;0.0459064946749471!GO:0008426;protein kinase C inhibitor activity;0.0459064946749471!GO:0046112;nucleobase biosynthetic process;0.0459064946749471!GO:0006509;membrane protein ectodomain proteolysis;0.0459843120895235!GO:0033619;membrane protein proteolysis;0.0459843120895235!GO:0000726;non-recombinational repair;0.0462291658648455!GO:0031326;regulation of cellular biosynthetic process;0.0462933084835114!GO:0009218;pyrimidine ribonucleotide metabolic process;0.0484172352253908!GO:0016628;oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor;0.0491231852896329!GO:0042026;protein refolding;0.0491231852896329!GO:0005875;microtubule associated complex;0.0492789608836063!GO:0006769;nicotinamide metabolic process;0.0498167770263874!GO:0008333;endosome to lysosome transport;0.0498306216464374!GO:0030911;TPR domain binding;0.0498494415553653 | |||
|sample_id=10638 | |||
|sample_note= | |||
|sample_sex=female | |||
|sample_species=Human (Homo sapiens) | |||
|sample_strain= | |||
|sample_tissue=ovary | |||
|top_motifs=TEF:2.33570062342;FOXQ1:2.33357888921;ZBTB16:1.95100576269;ARID5B:1.88162818741;ALX1:1.72905190306;NKX2-1,4:1.62226585441;POU1F1:1.59645338195;PITX1..3:1.58596600505;ONECUT1,2:1.33776241987;AIRE:1.29450758174;STAT5{A,B}:1.27732328183;PAX8:1.23604883962;ZEB1:1.22570514493;HNF1A:1.19904923809;ALX4:1.10440247792;UFEwm:1.06335472151;IKZF1:1.01244164047;CDC5L:0.997517257759;IKZF2:0.980621124331;MYOD1:0.880743557472;PPARG:0.871249439002;E2F1..5:0.86486814242;bHLH_family:0.829698728885;NFY{A,B,C}:0.821278520831;SNAI1..3:0.799842258935;NKX3-1:0.741568705788;HSF1,2:0.699192351336;NKX6-1,2:0.696557632038;TBX4,5:0.68156175;MYB:0.668574101623;EVI1:0.644937804474;PBX1:0.631966404881;CDX1,2,4:0.618077834761;FOXP1:0.612842285884;ESRRA:0.596162989911;RXRA_VDR{dimer}:0.557836631765;LMO2:0.555232515298;POU2F1..3:0.524618744938;LHX3,4:0.521054451178;ZNF143:0.489157912411;TEAD1:0.442713023977;NFKB1_REL_RELA:0.442329867978;ELK1,4_GABP{A,B1}:0.426988813998;NRF1:0.362964999089;NKX3-2:0.35825346193;NKX2-2,8:0.353695733619;EN1,2:0.327571348305;NR3C1:0.325628645729;PAX4:0.286734915249;ZIC1..3:0.284171794537;NFE2:0.274635259834;TOPORS:0.235160120278;RBPJ:0.191888977665;NR1H4:0.183239001894;NR5A1,2:0.174997189856;ZFP161:0.15888863459;GFI1:0.149334557491;RXR{A,B,G}_{NR1H2,PPAR}dimers:0.146396308491;HNF4A_NR2F1,2:0.14033175252;FOSL2:0.126665645715;RORA:0.121697392555;NKX2-3_NKX2-5:0.10567970112;POU3F1..4:0.105345094512;FOXM1:0.100945053655;FOS_FOS{B,L1}_JUN{B,D}:0.0756459587463;RXR{A,B,G}:0.0713628877453;YY1:0.0711970980645;XCPE1{core}:0.0706624727446;RFX1:0.0698560823402;TFDP1:0.0685488383001;FOXD3:0.0664849298182;FOX{F1,F2,J1}:0.0657328788541;TP53:0.0639112463619;FOX{I1,J2}:0.0630974066282;KLF4:0.0332283387666;PAX6:0.0325339414672;STAT2,4,6:0.0178263653308;NFE2L1:0.00542534550299;RFX2..5_RFXANK_RFXAP:-0.00974076682465;MYBL2:-0.0320509693322;BREu{core}:-0.0586458057089;HIF1A:-0.0672038033117;ADNP_IRX_SIX_ZHX:-0.077596978688;BACH2:-0.0776962949315;HOX{A5,B5}:-0.0843711934495;TAL1_TCF{3,4,12}:-0.107349893633;ZBTB6:-0.130652725082;ZNF384:-0.151758706342;GLI1..3:-0.155518569603;NFE2L2:-0.201528717997;STAT1,3:-0.219340100315;GZF1:-0.220252912837;PAX5:-0.228544215916;EBF1:-0.230122177426;ZNF423:-0.245345360802;XBP1:-0.283367703446;SOX{8,9,10}:-0.29417789178;NANOG:-0.295672360302;ATF2:-0.305001891999;SP1:-0.308052027471;OCT4_SOX2{dimer}:-0.31082691832;HOX{A4,D4}:-0.322226953254;PAX1,9:-0.358602000262;FOXN1:-0.376480178506;IRF7:-0.382731684275;RREB1:-0.383403830397;CUX2:-0.387669767846;DBP:-0.393018917327;EP300:-0.395197884756;ESR1:-0.395767081712;NR6A1:-0.39928273792;FOXP3:-0.405917815129;PAX2:-0.411186666933;CRX:-0.415113881558;IRF1,2:-0.45136284733;T:-0.467717265993;ATF5_CREB3:-0.473389440249;LEF1_TCF7_TCF7L1,2:-0.473882249046;HOXA9_MEIS1:-0.483926544715;CEBPA,B_DDIT3:-0.491227114411;HMGA1,2:-0.491678903109;SOX2:-0.4924223837;ATF4:-0.501980850582;REST:-0.514246371874;TBP:-0.529178511449;ATF6:-0.532729628624;FOXA2:-0.538571400788;FOXL1:-0.538646079494;AR:-0.548846399041;POU6F1:-0.549163473707;EGR1..3:-0.549646833565;GATA6:-0.558718332902;BPTF:-0.561047156221;GTF2I:-0.561515104246;MED-1{core}:-0.574445923507;MEF2{A,B,C,D}:-0.578464901311;ARNT_ARNT2_BHLHB2_MAX_MYC_USF1:-0.586549955495;SPI1:-0.591575397703;ELF1,2,4:-0.593752661759;TFAP2B:-0.597261020479;SPIB:-0.624678320159;PRRX1,2:-0.626628729654;PRDM1:-0.642783819805;NFIX:-0.643065807558;ETS1,2:-0.649416892445;GFI1B:-0.667110327399;CREB1:-0.669582254299;HOX{A6,A7,B6,B7}:-0.670823762141;POU5F1:-0.688184606765;AHR_ARNT_ARNT2:-0.694906016754;TLX1..3_NFIC{dimer}:-0.708527769477;MYFfamily:-0.718153818565;TFAP2{A,C}:-0.734090885148;HIC1:-0.744594233031;PAX3,7:-0.745078255054;RUNX1..3:-0.759397494862;TLX2:-0.760436374311;FOXO1,3,4:-0.766790639996;MTE{core}:-0.767549056116;GTF2A1,2:-0.775732722519;PDX1:-0.79570813295;NFIL3:-0.799015436682;HES1:-0.824052554402;HAND1,2:-0.826178975253;MTF1:-0.827595299412;GCM1,2:-0.829772532767;DMAP1_NCOR{1,2}_SMARC:-0.881642816552;NFATC1..3:-0.882910605838;VSX1,2:-0.907847692718;SPZ1:-0.908947563842;MZF1:-0.914179171284;TFCP2:-0.956669774583;HLF:-0.959625522541;NANOG{mouse}:-0.962620181458;SOX17:-0.999657222834;ZNF148:-1.02055539019;MAZ:-1.03911104987;SREBF1,2:-1.08327639023;FOX{D1,D2}:-1.08758211366;JUN:-1.10117469035;GATA4:-1.11352069976;SRF:-1.15988490364;PATZ1:-1.18139069076;SOX5:-1.21244370139;HBP1_HMGB_SSRP1_UBTF:-1.23109090412;TFAP4:-1.29790939568;HMX1:-1.30206647189;TGIF1:-1.53916560521;MAFB:-1.57426265401;NHLH1,2:-1.58094090901;ZNF238:-1.60612636588;SMAD1..7,9:-1.79962288413 | |||
|xref= | |||
|zenbu_report=https://fantom.gsc.riken.jp/zenbu/reports/#miRNA_expression_atlas_human;search_select_hide=table111:FF:10638-108I8;search_select_hide=table117:FF:10638-108I8 | |||
}} | }} |
Latest revision as of 14:32, 3 June 2020
Name: | clear cell carcinoma cell line:JHOC-5 |
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Species: | Human (Homo sapiens) |
Library ID: | CNhs11745 |
Sample type: | cell lines |
Genomic View: | UCSC |
RefEX: | Specific genes |
CAGEd-oPOSSUM: | link |
ZENBU report : | link |
Additional information | ||||||||||||||||||||||||||||
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Sample information
RNA information
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CAGE Accession numbers | ||||||||||||||||||||||||||||||||||||||||||||||
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Download raw sequence, BAM & CTSS | ||||||||||||||
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Relative expression to median (log10)
Transcription factors with enriched expression in this sampleRanked list of transcription factor promoter expression in this sample relative to the median expression in the FANTOM5 collection is shown. Value is log10 transformed.
Co-expression clusters with enriched expression in this sampleRanked list of co-expression cluster expression in this sample relative to the median expression in the FANTOM5 collection is shown. Value is log10 transformed. <br>Analyst:NA <br><br>link to dataset.<br>data
Repeat families with enriched expression in this sample<b>Summary:</b>Ranked list of repeat family expression in this sample relative tothe median expression in the FANTOM5 collection is shown. Value is log10transformed.<br><b>Analyst:</b>NA<br><br>link to dataset.<br>data
TFBS(DNA)motifs over-represented in proximal region of promoters active in this sample
JASPAR motifs<b>Summary:</b>Association of JASPAR motif to the promoter expression in thissample. Pearson's correlation between the number of TFBSs estimated byusing the position-weight matrix for each promoter and its expression isexpressed as Z-score by taking the ones based on random position-weightmatrix, and the tail probability of the normal distribution correspondingto the Z-score is taken as the resulting P-value. Lower P-value indicatesmore (non-random) association of the motif to promoter expression<br><b>Analyst:</b> Michiel de Hoon <br><br><br>link to dataset.<br>data
library id: CNhs11745
FANTOM5 phase1 novel unique motifs<b>Summary:</b>Association of the 169 novel and unique motifs discovered in FANTOM5 phase1 in this sample. Among the de-novo motifs discovered by DMF, HOMER,ChIPMunk, and ScanAll, only novel motifs are selected after comparison with known motif sets, and their clustering based on MACRO-APE resulted in169 novel and unique motifs. Their association to the promoter expression is evaluated in the same way to the JASPAR motif above<br><b>Analyst:</b> Michiel de Hoon <br><br><br>link to dataset.<br>data
library id: CNhs11745
Novel motif | Logo | P-value |
---|---|---|
1 | 1 | 0.0898 |
10 | 10 | 0.111 |
100 | 100 | 0.00105 |
101 | 101 | 0.178 |
102 | 102 | 0.638 |
103 | 103 | 0.411 |
104 | 104 | 0.962 |
105 | 105 | 0.143 |
106 | 106 | 0.701 |
107 | 107 | 0.276 |
108 | 108 | 0.534 |
109 | 109 | 0.0551 |
11 | 11 | 0.163 |
110 | 110 | 0.0531 |
111 | 111 | 0.15 |
112 | 112 | 0.5 |
113 | 113 | 0.0218 |
114 | 114 | 0.84 |
115 | 115 | 0.336 |
116 | 116 | 0.39 |
117 | 117 | 0.154 |
118 | 118 | 0.0148 |
119 | 119 | 0.159 |
12 | 12 | 0.324 |
120 | 120 | 0.0979 |
121 | 121 | 0.54 |
122 | 122 | 0.263 |
123 | 123 | 0.557 |
124 | 124 | 0.286 |
125 | 125 | 0.272 |
126 | 126 | 0.4 |
127 | 127 | 0.77 |
128 | 128 | 0.766 |
129 | 129 | 0.272 |
13 | 13 | 8.78508e-4 |
130 | 130 | 0.806 |
131 | 131 | 0.931 |
132 | 132 | 0.852 |
133 | 133 | 0.113 |
134 | 134 | 0.104 |
135 | 135 | 0.0204 |
136 | 136 | 0.0104 |
137 | 137 | 0.349 |
138 | 138 | 0.777 |
139 | 139 | 0.0936 |
14 | 14 | 0.728 |
140 | 140 | 0.788 |
141 | 141 | 0.675 |
142 | 142 | 0.807 |
143 | 143 | 0.0422 |
144 | 144 | 0.925 |
145 | 145 | 0.5 |
146 | 146 | 0.236 |
147 | 147 | 0.94 |
148 | 148 | 0.569 |
149 | 149 | 0.711 |
15 | 15 | 0.306 |
150 | 150 | 0.603 |
151 | 151 | 0.8 |
152 | 152 | 0.327 |
153 | 153 | 0.775 |
154 | 154 | 0.404 |
155 | 155 | 0.924 |
156 | 156 | 0.971 |
157 | 157 | 0.426 |
158 | 158 | 0.178 |
159 | 159 | 0.188 |
16 | 16 | 0.308 |
160 | 160 | 0.159 |
161 | 161 | 0.58 |
162 | 162 | 0.69 |
163 | 163 | 0.876 |
164 | 164 | 0.0142 |
165 | 165 | 0.826 |
166 | 166 | 0.996 |
167 | 167 | 0.189 |
168 | 168 | 0.8 |
169 | 169 | 0.8 |
17 | 17 | 0.931 |
18 | 18 | 0.959 |
19 | 19 | 0.914 |
2 | 2 | 0.205 |
20 | 20 | 0.0313 |
21 | 21 | 0.108 |
22 | 22 | 0.307 |
23 | 23 | 0.878 |
24 | 24 | 0.446 |
25 | 25 | 0.983 |
26 | 26 | 0.0271 |
27 | 27 | 0.352 |
28 | 28 | 0.711 |
29 | 29 | 0.0269 |
3 | 3 | 0.503 |
30 | 30 | 0.882 |
31 | 31 | 0.46 |
32 | 32 | 0.337 |
33 | 33 | 0.0474 |
34 | 34 | 0.0928 |
35 | 35 | 0.907 |
36 | 36 | 0.123 |
37 | 37 | 0.12 |
38 | 38 | 0.696 |
39 | 39 | 0.509 |
4 | 4 | 0.996 |
40 | 40 | 0.0222 |
41 | 41 | 0.027 |
42 | 42 | 0.548 |
43 | 43 | 0.964 |
44 | 44 | 0.023 |
45 | 45 | 0.34 |
46 | 46 | 0.419 |
47 | 47 | 0.145 |
48 | 48 | 0.0763 |
49 | 49 | 0.424 |
5 | 5 | 0.731 |
50 | 50 | 0.628 |
51 | 51 | 0.868 |
52 | 52 | 0.437 |
53 | 53 | 0.315 |
54 | 54 | 0.741 |
55 | 55 | 0.697 |
56 | 56 | 0.757 |
57 | 57 | 0.354 |
58 | 58 | 0.683 |
59 | 59 | 0.722 |
6 | 6 | 0.339 |
60 | 60 | 0.674 |
61 | 61 | 0.627 |
62 | 62 | 0.732 |
63 | 63 | 0.461 |
64 | 64 | 0.526 |
65 | 65 | 0.975 |
66 | 66 | 0.515 |
67 | 67 | 0.906 |
68 | 68 | 0.98 |
69 | 69 | 0.518 |
7 | 7 | 0.63 |
70 | 70 | 0.275 |
71 | 71 | 0.169 |
72 | 72 | 0.264 |
73 | 73 | 0.863 |
74 | 74 | 0.559 |
75 | 75 | 0.0979 |
76 | 76 | 0.174 |
77 | 77 | 0.317 |
78 | 78 | 0.119 |
79 | 79 | 0.843 |
8 | 8 | 0.457 |
80 | 80 | 0.00174 |
81 | 81 | 0.714 |
82 | 82 | 0.445 |
83 | 83 | 0.904 |
84 | 84 | 0.902 |
85 | 85 | 0.372 |
86 | 86 | 0.587 |
87 | 87 | 0.0898 |
88 | 88 | 0.498 |
89 | 89 | 0.923 |
9 | 9 | 0.0955 |
90 | 90 | 0.208 |
91 | 91 | 0.177 |
92 | 92 | 0.993 |
93 | 93 | 0.38 |
94 | 94 | 0.286 |
95 | 95 | 0.229 |
96 | 96 | 0.769 |
97 | 97 | 0.787 |
98 | 98 | 0.511 |
99 | 99 | 0.362 |
de novo motifs identified by HOMER in promoters active in this sample<b>Summary:</b>The result of HOMER in this sample is shown.<br><b>Analyst:</b>NA <br>
library id: CNhs11745
FANTOM5 (FF) ontology
Direct parent terms
is_a relathionship
EFO:0002091 biological replicate
FF:0000210 human sample
FF:0102787 clear cell adenocarcinoma cell sample
Ancestor terms (non development)<b>Summary:</b>Connected ontology terms with is_a, part_of or located_in relationship <br><b>Analyst:</b> Hideya Kawaji<br><br>link to source data<br>data
CL: Cell type
0000000 (cell), 0000000 (cell)
0000003 (native cell)
0000548 (animal cell)
0000066 (epithelial cell)
0000255 (eukaryotic cell)
DOID: Disease
4 (disease)
0050686 (organ system cancer)
162 (cancer)
14566 (disease of cellular proliferation)
0050687 (cell type cancer)
193 (reproductive organ cancer)
305 (carcinoma)
120 (female reproductive organ cancer)
299 (adenocarcinoma)
4468 (clear cell adenocarcinoma)
FF: FANTOM5
0000102 (sample by type)
0000003 (cell line sample)
0000210 (human sample)
0000101 (sample by species)
0000001 (sample)
0100297 (carcinoma cell line sample)
0101120 (epithelial cell line sample)
0100167 (adenocarcinoma cell line sample)
0102787 (clear cell adenocarcinoma cell sample)
Ancestor terms (development)<b>Summary:</b>Connected ontology terms with develops_from, derives_from or preceded_by relationship <br><b>Analyst:</b> Hideya Kawaji <br><br>link to source data<br>data
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