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|namespace=
|namespace=
|def="A genital tubercle is a body of tissue present in the development of the urinary and reproductive organs. It forms in the ventral, caudal region of mammalian embryos of both sexes, and eventually develops into a phallus. In the human fetus the genital tubercle develops around week 4 of gestation, and by week 9 becomes recognizably either a clitoris or penis. This should not be confused with the sinus tubercle which is a proliferation of endoderm induced by paramesonephic ducts. Even after the phallus is developed, the term genital tubercle remains, but only as the terminal end of it[2], which develops into either the glans penis or the glans clitoridis. The genital tubercle is sensitive to dihydrotestosterone and rich in 5-alpha-reductase, so that the amount of fetal testosterone present after the second month is a major determinant of phallus size at birth.[WP]." [Wikipedia:Genital_tubercle]
|def="A genital tubercle is a body of tissue present in the development of the urinary and reproductive organs. It forms in the ventral, caudal region of mammalian embryos of both sexes, and eventually develops into a phallus. In the human fetus the genital tubercle develops around week 4 of gestation, and by week 9 becomes recognizably either a clitoris or penis. This should not be confused with the sinus tubercle which is a proliferation of endoderm induced by paramesonephic ducts. Even after the phallus is developed, the term genital tubercle remains, but only as the terminal end of it[2], which develops into either the glans penis or the glans clitoridis. The genital tubercle is sensitive to dihydrotestosterone and rich in 5-alpha-reductase, so that the amount of fetal testosterone present after the second month is a major determinant of phallus size at birth.[WP]." [Wikipedia:Genital_tubercle]
|xref=EHDAA:5925;;EHDAA2:0000705;;EMAPA:17382;;SCTID:308798005
|xref=EHDAA2:0000705;;EHDAA:5925;;EMAPA:17382;;http://upload.wikimedia.org/wikipedia/commons/d/d6/Gray1119.png;;SCTID:308798005
|is_a=UBERON:0005423
|is_a=UBERON:0005423
|synonym=
|synonym="tuberculum phallicum; tuberculum genitale" RELATED LATIN [Wikipedia:Genital_tubercle]
|comment=Taxon notes: todo - add taxon constraints
|comment=Taxon notes: todo - add taxon constraints
|alt_id=
|alt_id=
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|obo_creation_date=
|obo_creation_date=
|subset=
|subset=
|adjacent_to=
|derives_from=
|derives_from=
|develops_from=UBERON:0004874
|develops_from=
|has_quality=
|has_quality=
|located_in=
|located_in=
|part_of=UBERON:0000922;;UBERON:0000990
|part_of=
|property_value=IAO:0000412 http://purl.obolibrary.org/obo/uberon.owl
|property_value=IAO:0000412 http://purl.obolibrary.org/obo/uberon.owl
|is_obsolete=
|is_obsolete=
|preceded_by=
|preceded_by=
}}
}}

Revision as of 17:06, 26 June 2012

Name:genital tubercle
Definition:"A genital tubercle is a body of tissue present in the development of the urinary and reproductive organs. It forms in the ventral, caudal region of mammalian embryos of both sexes, and eventually develops into a phallus. In the human fetus the genital tubercle develops around week 4 of gestation, and by week 9 becomes recognizably either a clitoris or penis. This should not be confused with the sinus tubercle which is a proliferation of endoderm induced by paramesonephic ducts. Even after the phallus is developed, the term genital tubercle remains, but only as the terminal end of it[2], which develops into either the glans penis or the glans clitoridis. The genital tubercle is sensitive to dihydrotestosterone and rich in 5-alpha-reductase, so that the amount of fetal testosterone present after the second month is a major determinant of phallus size at birth.[WP]." [Wikipedia:Genital_tubercle]
Xrefs:
links:

EHDAA2:0000705
EHDAA:5925
EMAPA:17382
[ Gray1119.png Gray1119.png]

SCTID:308798005
Synonyms: "tuberculum phallicum; tuberculum genitale" RELATED LATIN [Wikipedia:Genital_tubercle]
Comments:Taxon notes: todo - add taxon constraints

Ontology association<br>Each term has an is_a parent in the Uberon Ontology, which has a linkage to an another entity and FANTOM5 samples.Libraries were grouped into mutually exclusive facets according to the FANTOM5 sample ontology mapping to UBERON ontologies.<br><br>link to ontology dataset<br>data

Parents

is_a:UBERON:0005423(developing anatomical structure)



Children

develops from:UBERON:0000989 (penis)

Ontology Tree: Loaded from BioPortal

Ontorolgy tree(Small window open)

FF samples<br>It includes FANTOM5 samples that overlay the Uberon ontology



Enrichment analysis: top 100 FFCP enriched with this ontology term TOP 100 FANTOM5 Cage Peaks enriched with UBERON:0005876 (genital tubercle), sorted by p-values <br>Analyst: Hideya Kawaji<br><br>link to source dataset <br>human : data <br>mouse : data

P-valueFFCPShort description
9.37e-99FFCP PHASE1:Hg19::chr12:53068923..53068932,-#_5e7db072831b5150ffb0710557ecfa49p@chr12:53068923..53068932, -
9.37e-99FFCP PHASE2:Hg19::chr12:53068889..53068898,-#_5e7db072831b5150ffb0710557ecfa49p@chr12:53068889..53068898, -
9.37e-99FFCP PHASE2:Hg19::chr12:53068923..53068932,-#_5e7db072831b5150ffb0710557ecfa49p@chr12:53068923..53068932, -
9.37e-99FFCP PHASE1:Hg19::chr12:53068889..53068898,-#_5e7db072831b5150ffb0710557ecfa49p@chr12:53068889..53068898, -
2.55e-98FFCP PHASE2:Hg19::chr6:110964453..110964459,-#_1438dee19778d515afcb329931874abbp16@CDK19
2.55e-98FFCP PHASE1:Hg19::chr9:79379348..79379360,+#_1438dee19778d515afcb329931874abbp1@PCA3
2.55e-98FFCP PHASE1:Hg19::chr5:59672718..59672753,-#_1438dee19778d515afcb329931874abbp@chr5:59672718..59672753, -
2.55e-98FFCP PHASE1:Hg19::chr17:38976407..38976413,-#_1438dee19778d515afcb329931874abbp20@KRT10
2.55e-98FFCP PHASE1:Hg19::chr8:72252453..72252458,-#_1438dee19778d515afcb329931874abbp@chr8:72252453..72252458, -
2.55e-98FFCP PHASE2:Hg19::chr15:45803320..45803343,+#_1438dee19778d515afcb329931874abbp1@HMGN2P46
2.55e-98FFCP PHASE2:Hg19::chr9:79379348..79379360,+#_1438dee19778d515afcb329931874abbp1@PCA3
2.55e-98FFCP PHASE1:Hg19::chr17:38975820..38975830,-#_1438dee19778d515afcb329931874abbp10@KRT10
2.55e-98FFCP PHASE2:Hg19::chr16:15811123..15811133,+#_1438dee19778d515afcb329931874abbp@chr16:15811123..15811133, +
2.55e-98FFCP PHASE2:Hg19::chr17:38976407..38976413,-#_1438dee19778d515afcb329931874abbp20@KRT10
2.55e-98FFCP PHASE1:Hg19::chr6:110964453..110964459,-#_1438dee19778d515afcb329931874abbp16@CDK19
2.55e-98FFCP PHASE2:Hg19::chr17:38975820..38975830,-#_1438dee19778d515afcb329931874abbp10@KRT10
2.55e-98FFCP PHASE2:Hg19::chr5:59672718..59672753,-#_1438dee19778d515afcb329931874abbp@chr5:59672718..59672753, -
2.55e-98FFCP PHASE1:Hg19::chr15:45803320..45803343,+#_1438dee19778d515afcb329931874abbp1@HMGN2P46
2.55e-98FFCP PHASE2:Hg19::chr8:72252453..72252458,-#_1438dee19778d515afcb329931874abbp@chr8:72252453..72252458, -
2.55e-98FFCP PHASE1:Hg19::chr16:15811123..15811133,+#_1438dee19778d515afcb329931874abbp@chr16:15811123..15811133, +
1.23e-66FFCP PHASE2:Hg19::chr12:53068552..53068579,-#_1b14772be9e034606441087efa061c41p@chr12:53068552..53068579, -
1.23e-66FFCP PHASE2:Hg19::chr14:74454889..74454892,-#_1b14772be9e034606441087efa061c41p10@ENTPD5
1.23e-66FFCP PHASE1:Hg19::chr12:53068552..53068579,-#_1b14772be9e034606441087efa061c41p@chr12:53068552..53068579, -
1.23e-66FFCP PHASE1:Hg19::chr14:74454889..74454892,-#_1b14772be9e034606441087efa061c41p10@ENTPD5
2.39e-66FFCP PHASE2:Hg19::chr17:38978526..38978535,+#_2f0a70bf8ef0c61d532e03445871595cp@chr17:38978526..38978535, +
2.39e-66FFCP PHASE1:Hg19::chr1:209545365..209545377,+#_2f0a70bf8ef0c61d532e03445871595cp1@ENST00000447257
2.39e-66FFCP PHASE1:Hg19::chr17:33640639..33640650,+#_2f0a70bf8ef0c61d532e03445871595cp@chr17:33640639..33640650, +
2.39e-66FFCP PHASE2:Hg19::chr1:61416169..61416181,-#_2f0a70bf8ef0c61d532e03445871595cp@chr1:61416169..61416181, -
2.39e-66FFCP PHASE1:Hg19::chr19:38664309..38664322,+#_2f0a70bf8ef0c61d532e03445871595cp@chr19:38664309..38664322, +
2.39e-66FFCP PHASE2:Hg19::chr19:51517928..51517936,-#_2f0a70bf8ef0c61d532e03445871595cp2@AK026045
2.39e-66FFCP PHASE1:Hg19::chr2:179399981..179399988,-#_2f0a70bf8ef0c61d532e03445871595cp@chr2:179399981..179399988, -
2.39e-66FFCP PHASE1:Hg19::chr4:186434325..186434339,-#_2f0a70bf8ef0c61d532e03445871595cp@chr4:186434325..186434339, -
2.39e-66FFCP PHASE2:Hg19::chr17:33640639..33640650,+#_2f0a70bf8ef0c61d532e03445871595cp@chr17:33640639..33640650, +
2.39e-66FFCP PHASE1:Hg19::chr17:38975796..38975805,-#_2f0a70bf8ef0c61d532e03445871595cp13@KRT10
2.39e-66FFCP PHASE2:Hg19::chr1:209545365..209545377,+#_2f0a70bf8ef0c61d532e03445871595cp1@ENST00000447257
2.39e-66FFCP PHASE1:Hg19::chr2:179393635..179393640,-#_2f0a70bf8ef0c61d532e03445871595cp167@TTN
2.39e-66FFCP PHASE2:Hg19::chr19:38664309..38664322,+#_2f0a70bf8ef0c61d532e03445871595cp@chr19:38664309..38664322, +
2.39e-66FFCP PHASE2:Hg19::chr2:179399981..179399988,-#_2f0a70bf8ef0c61d532e03445871595cp@chr2:179399981..179399988, -
2.39e-66FFCP PHASE1:Hg19::chr17:38976909..38976919,-#_2f0a70bf8ef0c61d532e03445871595cp@chr17:38976909..38976919, -
2.39e-66FFCP PHASE2:Hg19::chr17:38975796..38975805,-#_2f0a70bf8ef0c61d532e03445871595cp13@KRT10
2.39e-66FFCP PHASE1:Hg19::chr6:152585338..152585342,-#_2f0a70bf8ef0c61d532e03445871595cp@chr6:152585338..152585342, -
2.39e-66FFCP PHASE2:Hg19::chr2:179393635..179393640,-#_2f0a70bf8ef0c61d532e03445871595cp167@TTN
2.39e-66FFCP PHASE2:Hg19::chr4:186434325..186434339,-#_2f0a70bf8ef0c61d532e03445871595cp@chr4:186434325..186434339, -
2.39e-66FFCP PHASE2:Hg19::chr17:38976909..38976919,-#_2f0a70bf8ef0c61d532e03445871595cp@chr17:38976909..38976919, -
2.39e-66FFCP PHASE1:Hg19::chr17:38975850..38975854,-#_2f0a70bf8ef0c61d532e03445871595cp19@KRT10
2.39e-66FFCP PHASE2:Hg19::chr6:152585338..152585342,-#_2f0a70bf8ef0c61d532e03445871595cp@chr6:152585338..152585342, -
2.39e-66FFCP PHASE1:Hg19::chr17:38978526..38978535,+#_2f0a70bf8ef0c61d532e03445871595cp@chr17:38978526..38978535, +
2.39e-66FFCP PHASE1:Hg19::chr1:61416169..61416181,-#_2f0a70bf8ef0c61d532e03445871595cp@chr1:61416169..61416181, -
2.39e-66FFCP PHASE1:Hg19::chr19:51517928..51517936,-#_2f0a70bf8ef0c61d532e03445871595cp2@AK026045
2.39e-66FFCP PHASE2:Hg19::chr17:38975850..38975854,-#_2f0a70bf8ef0c61d532e03445871595cp19@KRT10
4.66e-66FFCP PHASE1:Hg19::chr2:152520302..152520308,-#_83ff3f07055979f07c17f4d1de996ac6p@chr2:152520302..152520308, -
4.66e-66FFCP PHASE1:Hg19::chr16:34571309..34571314,-#_83ff3f07055979f07c17f4d1de996ac6p@chr16:34571309..34571314, -
4.66e-66FFCP PHASE2:Hg19::chr5:66771311..66771320,-#_83ff3f07055979f07c17f4d1de996ac6p2@ENST00000508512
4.66e-66FFCP PHASE2:Hg19::chr2:152520302..152520308,-#_83ff3f07055979f07c17f4d1de996ac6p@chr2:152520302..152520308, -
4.66e-66FFCP PHASE1:Hg19::chr2:152520333..152520340,-#_83ff3f07055979f07c17f4d1de996ac6p@chr2:152520333..152520340, -
4.66e-66FFCP PHASE1:Hg19::chr2:152548420..152548425,-#_83ff3f07055979f07c17f4d1de996ac6p@chr2:152548420..152548425, -
4.66e-66FFCP PHASE1:Hg19::chr2:75869014..75869047,+#_83ff3f07055979f07c17f4d1de996ac6p@chr2:75869014..75869047, +
4.66e-66FFCP PHASE1:Hg19::chr3:52875783..52875812,-#_83ff3f07055979f07c17f4d1de996ac6p7@TMEM110
4.66e-66FFCP PHASE2:Hg19::chr2:152520333..152520340,-#_83ff3f07055979f07c17f4d1de996ac6p@chr2:152520333..152520340, -
4.66e-66FFCP PHASE2:Hg19::chr13:103555720..103555725,+#_83ff3f07055979f07c17f4d1de996ac6p@chr13:103555720..103555725, +
4.66e-66FFCP PHASE2:Hg19::chr2:152548420..152548425,-#_83ff3f07055979f07c17f4d1de996ac6p@chr2:152548420..152548425, -
4.66e-66FFCP PHASE2:Hg19::chr2:75869014..75869047,+#_83ff3f07055979f07c17f4d1de996ac6p@chr2:75869014..75869047, +
4.66e-66FFCP PHASE2:Hg19::chr3:52875783..52875812,-#_83ff3f07055979f07c17f4d1de996ac6p7@TMEM110
4.66e-66FFCP PHASE1:Hg19::chr2:179542558..179542568,-#_83ff3f07055979f07c17f4d1de996ac6p@chr2:179542558..179542568, -
4.66e-66FFCP PHASE1:Hg19::chr13:103555720..103555725,+#_83ff3f07055979f07c17f4d1de996ac6p@chr13:103555720..103555725, +
4.66e-66FFCP PHASE1:Hg19::chr10:94301107..94301111,-#_83ff3f07055979f07c17f4d1de996ac6p18@IDE
4.66e-66FFCP PHASE2:Hg19::chr16:34571309..34571314,-#_83ff3f07055979f07c17f4d1de996ac6p@chr16:34571309..34571314, -
4.66e-66FFCP PHASE1:Hg19::chr5:66771311..66771320,-#_83ff3f07055979f07c17f4d1de996ac6p2@ENST00000508512
4.66e-66FFCP PHASE2:Hg19::chr10:94301107..94301111,-#_83ff3f07055979f07c17f4d1de996ac6p18@IDE
4.66e-66FFCP PHASE2:Hg19::chr2:179542558..179542568,-#_83ff3f07055979f07c17f4d1de996ac6p@chr2:179542558..179542568, -
1.46e-50FFCP PHASE1:Hg19::chr17:4448859..4448864,-#_a2e04505860d65be0c16040e12e87e4ep@chr17:4448859..4448864, -
1.46e-50FFCP PHASE1:Hg19::chr2:178753478..178753487,-#_a2e04505860d65be0c16040e12e87e4ep10@PDE11A
1.46e-50FFCP PHASE2:Hg19::chr17:4448859..4448864,-#_a2e04505860d65be0c16040e12e87e4ep@chr17:4448859..4448864, -
1.46e-50FFCP PHASE2:Hg19::chr2:178753478..178753487,-#_a2e04505860d65be0c16040e12e87e4ep10@PDE11A
2.42e-50FFCP PHASE1:Hg19::chr2:152554090..152554096,-#_4c39809d372b12014dff8d4f2f025fbap@chr2:152554090..152554096, -
2.42e-50FFCP PHASE2:Hg19::chr10:71351909..71351911,+#_4c39809d372b12014dff8d4f2f025fbap@chr10:71351909..71351911, +
2.42e-50FFCP PHASE2:Hg19::chr2:152554090..152554096,-#_4c39809d372b12014dff8d4f2f025fbap@chr2:152554090..152554096, -
2.42e-50FFCP PHASE1:Hg19::chr10:71351909..71351911,+#_4c39809d372b12014dff8d4f2f025fbap@chr10:71351909..71351911, +
2.42e-50FFCP PHASE1:Hg19::chr16:56598984..56598990,+#_4c39809d372b12014dff8d4f2f025fbap1@MT4
2.42e-50FFCP PHASE1:Hg19::chr17:10421962..10421969,-#_4c39809d372b12014dff8d4f2f025fbap2@MYH1
2.42e-50FFCP PHASE1:Hg19::chr2:170783857..170783860,+#_4c39809d372b12014dff8d4f2f025fbap@chr2:170783857..170783860, +
2.42e-50FFCP PHASE1:Hg19::chr20:33451327..33451358,-#_4c39809d372b12014dff8d4f2f025fbap4@GGT7
2.42e-50FFCP PHASE2:Hg19::chr17:10421962..10421969,-#_4c39809d372b12014dff8d4f2f025fbap2@MYH1
2.42e-50FFCP PHASE2:Hg19::chr10:15646574..15646578,-#_4c39809d372b12014dff8d4f2f025fbap11@ITGA8
2.42e-50FFCP PHASE1:Hg19::chr10:15646574..15646578,-#_4c39809d372b12014dff8d4f2f025fbap11@ITGA8
2.42e-50FFCP PHASE2:Hg19::chr2:170783857..170783860,+#_4c39809d372b12014dff8d4f2f025fbap@chr2:170783857..170783860, +
2.42e-50FFCP PHASE2:Hg19::chr20:33451327..33451358,-#_4c39809d372b12014dff8d4f2f025fbap4@GGT7
2.42e-50FFCP PHASE2:Hg19::chr16:56598984..56598990,+#_4c39809d372b12014dff8d4f2f025fbap1@MT4
3.99e-50FFCP PHASE2:Hg19::chr1:152483278..152483280,+#_93bee6b1718b7b6363a1a1c80287be41p1@LCE5A
3.99e-50FFCP PHASE1:Hg19::chr2:179399074..179399079,-#_93bee6b1718b7b6363a1a1c80287be41p@chr2:179399074..179399079, -
3.99e-50FFCP PHASE1:Hg19::chr5:66771335..66771342,-#_93bee6b1718b7b6363a1a1c80287be41p3@ENST00000508512
3.99e-50FFCP PHASE1:Hg19::chr17:38976882..38976895,-#_93bee6b1718b7b6363a1a1c80287be41p@chr17:38976882..38976895, -
3.99e-50FFCP PHASE2:Hg19::chr2:179399074..179399079,-#_93bee6b1718b7b6363a1a1c80287be41p@chr2:179399074..179399079, -
3.99e-50FFCP PHASE1:Hg19::chr2:152393727..152393736,-#_93bee6b1718b7b6363a1a1c80287be41p@chr2:152393727..152393736, -
3.99e-50FFCP PHASE1:Hg19::chr2:152348920..152348927,-#_93bee6b1718b7b6363a1a1c80287be41p@chr2:152348920..152348927, -
3.99e-50FFCP PHASE1:Hg19::chr6:56362490..56362515,-#_93bee6b1718b7b6363a1a1c80287be41p60@DST
3.99e-50FFCP PHASE2:Hg19::chr17:38976882..38976895,-#_93bee6b1718b7b6363a1a1c80287be41p@chr17:38976882..38976895, -
3.99e-50FFCP PHASE2:Hg19::chr5:66771335..66771342,-#_93bee6b1718b7b6363a1a1c80287be41p3@ENST00000508512
3.99e-50FFCP PHASE1:Hg19::chr5:38484957..38484965,-#_93bee6b1718b7b6363a1a1c80287be41p@chr5:38484957..38484965, -
3.99e-50FFCP PHASE2:Hg19::chr16:15865517..15865522,-#_93bee6b1718b7b6363a1a1c80287be41p@chr16:15865517..15865522, -

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