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Coexpression cluster:C3121: Difference between revisions

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|ontology_enrichment_disease=
|ontology_enrichment_disease=
|ontology_enrichment_uberon=UBERON:0007023!6.02e-28!115;UBERON:0001049!1.24e-26!57;UBERON:0005068!1.24e-26!57;UBERON:0006241!1.24e-26!57;UBERON:0007135!1.24e-26!57;UBERON:0002616!3.93e-24!59;UBERON:0005743!1.38e-23!86;UBERON:0000955!9.91e-23!69;UBERON:0006238!9.91e-23!69;UBERON:0001017!5.38e-22!82;UBERON:0003075!6.48e-21!86;UBERON:0007284!6.48e-21!86;UBERON:0000073!4.57e-20!94;UBERON:0001016!4.57e-20!94;UBERON:0002346!1.68e-18!90;UBERON:0000033!2.15e-18!123;UBERON:0000153!4.93e-18!129;UBERON:0007811!4.93e-18!129;UBERON:0003080!1.14e-17!42;UBERON:0002780!2.31e-17!41;UBERON:0001890!2.31e-17!41;UBERON:0006240!2.31e-17!41;UBERON:0002020!1.28e-16!34;UBERON:0003528!1.28e-16!34;UBERON:0001893!1.41e-16!34;UBERON:0000475!6.61e-16!365;UBERON:0002791!7.32e-16!33;UBERON:0001869!1.53e-15!32;UBERON:0004121!6.38e-15!169;UBERON:0002619!3.43e-14!22;UBERON:0003056!5.28e-14!61;UBERON:0000924!1.26e-13!173;UBERON:0006601!1.26e-13!173;UBERON:0001950!5.79e-13!20;UBERON:0000956!2.12e-12!25;UBERON:0000203!2.12e-12!25;UBERON:0003076!2.27e-10!15;UBERON:0003057!2.27e-10!15;UBERON:0004732!2.01e-09!13;UBERON:0000479!4.41e-09!787;UBERON:0004733!8.52e-09!12;UBERON:0002028!8.52e-09!12;UBERON:0007277!8.52e-09!12;UBERON:0000468!1.08e-08!659;UBERON:0000481!5.55e-08!347;UBERON:0000062!8.42e-08!511;UBERON:0002680!5.81e-07!9;UBERON:0001895!5.81e-07!9;UBERON:0010092!5.81e-07!9;UBERON:0000483!6.75e-07!309
|ontology_enrichment_uberon=UBERON:0007023!6.02e-28!115;UBERON:0001049!1.24e-26!57;UBERON:0005068!1.24e-26!57;UBERON:0006241!1.24e-26!57;UBERON:0007135!1.24e-26!57;UBERON:0002616!3.93e-24!59;UBERON:0005743!1.38e-23!86;UBERON:0000955!9.91e-23!69;UBERON:0006238!9.91e-23!69;UBERON:0001017!5.38e-22!82;UBERON:0003075!6.48e-21!86;UBERON:0007284!6.48e-21!86;UBERON:0000073!4.57e-20!94;UBERON:0001016!4.57e-20!94;UBERON:0002346!1.68e-18!90;UBERON:0000033!2.15e-18!123;UBERON:0000153!4.93e-18!129;UBERON:0007811!4.93e-18!129;UBERON:0003080!1.14e-17!42;UBERON:0002780!2.31e-17!41;UBERON:0001890!2.31e-17!41;UBERON:0006240!2.31e-17!41;UBERON:0002020!1.28e-16!34;UBERON:0003528!1.28e-16!34;UBERON:0001893!1.41e-16!34;UBERON:0000475!6.61e-16!365;UBERON:0002791!7.32e-16!33;UBERON:0001869!1.53e-15!32;UBERON:0004121!6.38e-15!169;UBERON:0002619!3.43e-14!22;UBERON:0003056!5.28e-14!61;UBERON:0000924!1.26e-13!173;UBERON:0006601!1.26e-13!173;UBERON:0001950!5.79e-13!20;UBERON:0000956!2.12e-12!25;UBERON:0000203!2.12e-12!25;UBERON:0003076!2.27e-10!15;UBERON:0003057!2.27e-10!15;UBERON:0004732!2.01e-09!13;UBERON:0000479!4.41e-09!787;UBERON:0004733!8.52e-09!12;UBERON:0002028!8.52e-09!12;UBERON:0007277!8.52e-09!12;UBERON:0000468!1.08e-08!659;UBERON:0000481!5.55e-08!347;UBERON:0000062!8.42e-08!511;UBERON:0002680!5.81e-07!9;UBERON:0001895!5.81e-07!9;UBERON:0010092!5.81e-07!9;UBERON:0000483!6.75e-07!309
|tf_chipseq_enrich=E2F1#1869;3:4.90738921487932:0.00846098534723939:0.0323660115991625!SUZ12#23512;3:50.1157809110629:7.93834897779404e-06:0.00022120416992845
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}}
}}

Revision as of 14:22, 5 September 2012


Full id: C3121_Osteoblast_cerebellum_temporal_postcentral_occipital_Myoblast_pons



Phase1 CAGE Peaks

Hg19::chr11:1770316..1770338,-p2@IFITM10
Hg19::chr11:1770353..1770372,-p4@IFITM10
Hg19::chr11:1770450..1770481,-p3@IFITM10


Enriched pathways on this co-expression cluster<b>Summary:</b><br>Canonical pathway gene sets were compiled from Reactome, Wikipathways and KEGG. For the major signaling pathways, the transcriptionally-regulated genes (downstream targets) were obtained from Netpath. Combined, the canonical pathways and downstream targets totaled 489 human gene sets. The corresponding M. musculus gene sets were inferred by homology using the HomoloGene database. Enrichment for each of the canonical 489 pathways and gene sets included in the co-expression cluster was assessed by the hypergeometric probability. The resulting P values were also then adjusted by the Benjamini-Hochberg method for multiple comparisons.<br><b>Analyst: </b>Emmanuel Dimont<br><br>link to source dataset<br>data


No results for this coexpression

Enriched Gene Ontology terms on this co-expression cluster<b>Summary:</b> Results for GOStat analysis on co-expressed clusters. Each cluster with promoters mapping to at least two different genes was analysed with GOStat (PMID: 14962934) with default parameter. <br><b>Analyst:</b> Erik Arner<br><br>link to source dataset<br>data


No GOStat results

Enriched sample ontology terms on this co-expression cluster<b>Summary:</b>To summarize promoter activities (expression profile of a TSS region) across ~1000 samples, we performed enrichment analysis based on FANTOM5 Sample Ontology (FF ontology). The question here is “in which type of samples the promoter is more active”. To answer this question, we compared expressions (TPMs) in the samples associated with a sample ontology term and the rest of the samples by using the Mann-Whitney rank sum test. To summarize ontologies enriched in this co-expression cluster, we ran the same analysis on an averaged expression profile of all promoters that make up. <b>Analyst:</b> Hideya Kawaji <br><br>links to source dataset<br><br>cell_data<br>uberon_data<br><br>


Cell Type
Ontology termp-valuen
non-terminally differentiated cell9.74e-07180
Uber Anatomy
Ontology termp-valuen
adult organism6.02e-28115
neural tube1.24e-2657
neural rod1.24e-2657
future spinal cord1.24e-2657
neural keel1.24e-2657
regional part of brain3.93e-2459
brain9.91e-2369
future brain9.91e-2369
central nervous system5.38e-2282
neural plate6.48e-2186
presumptive neural plate6.48e-2186
regional part of nervous system4.57e-2094
nervous system4.57e-2094
neurectoderm1.68e-1890
head2.15e-18123
anterior region of body4.93e-18129
craniocervical region4.93e-18129
anterior neural tube1.14e-1742
regional part of forebrain2.31e-1741
forebrain2.31e-1741
future forebrain2.31e-1741
gray matter1.28e-1634
brain grey matter1.28e-1634
telencephalon1.41e-1634
organism subdivision6.61e-16365
regional part of telencephalon7.32e-1633
cerebral hemisphere1.53e-1532
ectoderm-derived structure6.38e-15169
regional part of cerebral cortex3.43e-1422
pre-chordal neural plate5.28e-1461
ectoderm1.26e-13173
presumptive ectoderm1.26e-13173
neocortex5.79e-1320
cerebral cortex2.12e-1225
pallium2.12e-1225
posterior neural tube2.27e-1015
chordal neural plate2.27e-1015
segmental subdivision of nervous system2.01e-0913
tissue4.41e-09787
segmental subdivision of hindbrain8.52e-0912
hindbrain8.52e-0912
presumptive hindbrain8.52e-0912
multi-cellular organism1.08e-08659
multi-tissue structure5.55e-08347
organ8.42e-08511
regional part of metencephalon5.81e-079
metencephalon5.81e-079
future metencephalon5.81e-079
epithelium6.75e-07309


Overrepresented TFBS (DNA) motifs on this co-expression cluster<b>Summary:</b>The values shown are the p-values for overrepresentation of the motif in this coexpression cluster. So a small p-value means a strong overrepresentation. <b>Analyst:</b> Michiel de Hoon <br><br>link to source data <br> Novel motifs <br>data <br><br> Jaspar motifs <br>data


Novel motifs



JASPAR motifs

Motifs-log10(p-value)

{{{tfbs_overrepresentation_jaspar}}}



ENCODE TF ChIP-seq peak enrichment analysis<b>Summary:</b> For each TF and each co-expression cluster, the number of promoters with ENCODE TF ChIP signal was compared with the rest of promoters from the robust set using Fisher's exact test. Clusters with significant ChIP enrichment (q <= 0.05) after Benjamini-Hochberg correction were retained. <br><b>Analyst:</b> Erik Arner<br><br>link to source dataset<br><br>data


(#promoters = Number of promoters in this coexpression cluster that have ChIP signal of the TF)

TF#promotersEnrichmentp-valueq-value
E2F1#186934.907389214879320.008460985347239390.0323660115991625
SUZ12#23512350.11578091106297.93834897779404e-060.00022120416992845



Relative expression of the co-expression cluster<b>Summary:</b>Co-expression clusters are compared against FANTOM5 samples to obtain relative expression. <br><b>Analyst:</b>NA<br><br>link to data source<br> data


This analysis result is provided for C0 - C305 clusters.