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{{Coexpression_clusters
{{Coexpression_clusters
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|full_id=C4694_Mast_Neurons_parietal_small_medulloblastoma_occipital_temporal
|full_id=C4694_Mast_Neurons_parietal_small_medulloblastoma_occipital_temporal
|id=C4694
|id=C4694

Revision as of 17:48, 12 September 2012


Full id: C4694_Mast_Neurons_parietal_small_medulloblastoma_occipital_temporal



Phase1 CAGE Peaks

Hg19::chr7:70228182..70228210,+p@chr7:70228182..70228210
+
Hg19::chr7:70228238..70228275,+p@chr7:70228238..70228275
+
Hg19::chr7:70231159..70231182,+p7@AUTS2


Enriched pathways on this co-expression cluster<b>Summary:</b><br>Canonical pathway gene sets were compiled from Reactome, Wikipathways and KEGG. For the major signaling pathways, the transcriptionally-regulated genes (downstream targets) were obtained from Netpath. Combined, the canonical pathways and downstream targets totaled 489 human gene sets. The corresponding M. musculus gene sets were inferred by homology using the HomoloGene database. Enrichment for each of the canonical 489 pathways and gene sets included in the co-expression cluster was assessed by the hypergeometric probability. The resulting P values were also then adjusted by the Benjamini-Hochberg method for multiple comparisons.<br><b>Analyst: </b>Emmanuel Dimont<br><br>link to source dataset<br>data


No results for this coexpression

Enriched Gene Ontology terms on this co-expression cluster<b>Summary:</b> Results for GOStat analysis on co-expressed clusters. Each cluster with promoters mapping to at least two different genes was analysed with GOStat (PMID: 14962934) with default parameter. <br><b>Analyst:</b> Erik Arner<br><br>link to source dataset<br>data


No GOStat results

Enriched sample ontology terms on this co-expression cluster<b>Summary:</b>To summarize promoter activities (expression profile of a TSS region) across ~1000 samples, we performed enrichment analysis based on FANTOM5 Sample Ontology (FF ontology). The question here is “in which type of samples the promoter is more active”. To answer this question, we compared expressions (TPMs) in the samples associated with a sample ontology term and the rest of the samples by using the Mann-Whitney rank sum test. To summarize ontologies enriched in this co-expression cluster, we ran the same analysis on an averaged expression profile of all promoters that make up. <b>Analyst:</b> Hideya Kawaji <br><br>links to source dataset<br><br><br>uberon_data<br><br>


Uber Anatomy
Ontology termp-valuen
central nervous system1.88e-2782
regional part of nervous system6.18e-2694
nervous system6.18e-2694
neural tube5.25e-2557
neural rod5.25e-2557
future spinal cord5.25e-2557
neural keel5.25e-2557
ectoderm-derived structure1.07e-24169
ectoderm1.08e-24173
presumptive ectoderm1.08e-24173
anterior region of body2.59e-22129
craniocervical region2.59e-22129
neural plate1.23e-2186
presumptive neural plate1.23e-2186
neurectoderm2.46e-2190
head2.72e-21123
brain3.20e-2169
future brain3.20e-2169
adult organism1.30e-20115
regional part of brain1.78e-1959
anterior neural tube6.32e-1942
regional part of forebrain1.09e-1841
forebrain1.09e-1841
future forebrain1.09e-1841
gray matter1.89e-1734
brain grey matter1.89e-1734
pre-chordal neural plate4.70e-1761
telencephalon4.84e-1734
regional part of telencephalon9.60e-1733
cerebral hemisphere4.11e-1632
cerebral cortex2.41e-1225
pallium2.41e-1225
regional part of cerebral cortex3.25e-1222
neocortex5.06e-1120
posterior neural tube2.85e-0715
chordal neural plate2.85e-0715
basal ganglion7.47e-079
nuclear complex of neuraxis7.47e-079
aggregate regional part of brain7.47e-079
collection of basal ganglia7.47e-079
cerebral subcortex7.47e-079


Overrepresented TFBS (DNA) motifs on this co-expression cluster<b>Summary:</b>The values shown are the p-values for overrepresentation of the motif in this coexpression cluster. So a small p-value means a strong overrepresentation. <b>Analyst:</b> Michiel de Hoon <br><br>link to source data <br> Novel motifs <br>data <br><br> Jaspar motifs <br>data


Novel motifs



JASPAR motifs

Motifs-log10(p-value)

{{{tfbs_overrepresentation_jaspar}}}



ENCODE TF ChIP-seq peak enrichment analysis<b>Summary:</b> For each TF and each co-expression cluster, the number of promoters with ENCODE TF ChIP signal was compared with the rest of promoters from the robust set using Fisher's exact test. Clusters with significant ChIP enrichment (q <= 0.05) after Benjamini-Hochberg correction were retained. <br><b>Analyst:</b> Erik Arner<br><br>link to source dataset<br><br>data


No analysis results for this cluster

Relative expression of the co-expression cluster<b>Summary:</b>Co-expression clusters are compared against FANTOM5 samples to obtain relative expression. <br><b>Analyst:</b>NA<br><br>link to data source<br> data


This analysis result is provided for C0 - C305 clusters.