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MCL coexpression mm9:3616: Difference between revisions

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{{MCL_coexpression_mm9
{{MCL_coexpression_mm9
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|gostat_on_MCL_coexpression=GO:0008328;ionotropic glutamate receptor complex;0.014134662795157;14809!GO:0005234;extracellular-glutamate-gated ion channel activity;0.014134662795157;14809!GO:0004970;ionotropic glutamate receptor activity;0.014134662795157;14809!GO:0005231;excitatory extracellular ligand-gated ion channel activity;0.0207308387662302;14809!GO:0008066;glutamate receptor activity;0.0207308387662302;14809!GO:0005230;extracellular ligand-gated ion channel activity;0.0217255002221857;14809!GO:0043235;receptor complex;0.0217255002221857;14809!GO:0015276;ligand-gated ion channel activity;0.0217255002221857;14809!GO:0022834;ligand-gated channel activity;0.0217255002221857;14809!GO:0045211;postsynaptic membrane;0.0256779707445351;14809!GO:0044456;synapse part;0.0259135484577878;14809!
|gostat_on_MCL_coexpression=GO:0008328;ionotropic glutamate receptor complex;0.014134662795157;14809!GO:0005234;extracellular-glutamate-gated ion channel activity;0.014134662795157;14809!GO:0004970;ionotropic glutamate receptor activity;0.014134662795157;14809!GO:0005231;excitatory extracellular ligand-gated ion channel activity;0.0207308387662302;14809!GO:0008066;glutamate receptor activity;0.0207308387662302;14809!GO:0005230;extracellular ligand-gated ion channel activity;0.0217255002221857;14809!GO:0043235;receptor complex;0.0217255002221857;14809!GO:0015276;ligand-gated ion channel activity;0.0217255002221857;14809!GO:0022834;ligand-gated channel activity;0.0217255002221857;14809!GO:0045211;postsynaptic membrane;0.0256779707445351;14809!GO:0044456;synapse part;0.0259135484577878;14809!
}}
}}

Revision as of 13:32, 11 October 2012


Phase1 CAGE Peaks

 Short description
Mm9::chr7:25857276..25857305,-p6@Grik5
Mm9::chr7:25857306..25857385,-p2@Grik5
Mm9::chr9:58335890..58335917,+p1@6030419C18Rik


Enriched pathways on this co-expression cluster<b>Summary:</b><br>Canonical pathway gene sets were compiled from Reactome, Wikipathways and KEGG. For the major signaling pathways, the transcriptionally-regulated genes (downstream targets) were obtained from Netpath. Combined, the canonical pathways and downstream targets totaled 489 human gene sets. The corresponding M. musculus gene sets were inferred by homology using the HomoloGene database. Enrichment for each of the canonical 489 pathways and gene sets included in the co-expression cluster was assessed by the hypergeometric probability. The resulting P values were also then adjusted by the Benjamini-Hochberg method for multiple comparisons.<br><b>Analyst: </b>Emmanuel Dimont<br><br>link to source dataset<br>data

GO IDGO nameFDR corrected p-value
GO:0008328ionotropic glutamate receptor complex0.014134662795157
GO:0005234extracellular-glutamate-gated ion channel activity0.014134662795157
GO:0004970ionotropic glutamate receptor activity0.014134662795157
GO:0005231excitatory extracellular ligand-gated ion channel activity0.0207308387662302
GO:0008066glutamate receptor activity0.0207308387662302
GO:0005230extracellular ligand-gated ion channel activity0.0217255002221857
GO:0043235receptor complex0.0217255002221857
GO:0015276ligand-gated ion channel activity0.0217255002221857
GO:0022834ligand-gated channel activity0.0217255002221857
GO:0045211postsynaptic membrane0.0256779707445351
GO:0044456synapse part0.0259135484577878



Relative expression of the co-expression cluster over median <br>Analyst:




Enriched sample ontology terms on this co-expression cluster<b>Summary:</b>To summarize promoter activities (expression profile of a TSS region) across ~1000 samples, we performed enrichment analysis based on FANTOM5 Sample Ontology (FF ontology). The question here is “in which type of samples the promoter is more active”. To answer this question, we compared expressions (TPMs) in the samples associated with a sample ontology term and the rest of the samples by using the Mann-Whitney rank sum test. To summarize ontologies enriched in this co-expression cluster, we ran the same analysis on an averaged expression profile of all promoters that make up. <b>Analyst:</b> Hideya Kawaji <br><br>links to source dataset<br><br>cell_data<br>uberon_data<br>disease_data<br>

Cell Type
Ontology termp-valuen

Uber Anatomy
Ontology termp-valuen

Disease
Ontology termp-valuen


TFBS overrepresentation<b>Summary:</b>The values shown are the p-values for overrepresentation of the motif in this coexpression cluster. So a small p-value means a strong overrepresentation. <b>Analyst:</b> Michiel de Hoon <br><br>link to source data <br> Novel motifs <br>data <br><br> Jaspar motifs <br>data

Novel motifs




JASPAR motifs


Motifs-log10(p-value)

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