MCL coexpression mm9:1032

Phase1 CAGE Peaks

	Short description
Mm9::chr10:61693956..61693980,-	p1@Tspan15
Mm9::chr15:94459513..94459560,+	p2@Tmem117
Mm9::chr4:49610297..49610365,-	p1@2810432L12Rik
Mm9::chr5:115798721..115798747,-	p3@Cox6a1
Mm9::chr7:87080144..87080257,-	p1@2610034B18Rik
Mm9::chr9:56008805..56008852,-	p1@Tspan3
Mm9::chr9:56008858..56008882,-	p3@Tspan3

Enriched pathways on this co-expression cluster<b>Summary:</b><br>Canonical pathway gene sets were compiled from Reactome, Wikipathways and KEGG. For the major signaling pathways, the transcriptionally-regulated genes (downstream targets) were obtained from Netpath. Combined, the canonical pathways and downstream targets totaled 489 human gene sets. The corresponding M. musculus gene sets were inferred by homology using the HomoloGene database. Enrichment for each of the canonical 489 pathways and gene sets included in the co-expression cluster was assessed by the hypergeometric probability. The resulting P values were also then adjusted by the Benjamini-Hochberg method for multiple comparisons.<br><b>Analyst: </b>Emmanuel Dimont<br><br>link to source dataset<br>data

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GO ID	GO name	FDR corrected p-value
GO:0016021	integral to membrane	0.0344393122232849
GO:0031224	intrinsic to membrane	0.0344393122232849
GO:0044425	membrane part	0.0344393122232849
GO:0004129	cytochrome-c oxidase activity	0.0344393122232849
GO:0016675	oxidoreductase activity, acting on heme group of donors	0.0344393122232849
GO:0016676	oxidoreductase activity, acting on heme group of donors, oxygen as acceptor	0.0344393122232849
GO:0015002	heme-copper terminal oxidase activity	0.0344393122232849

Relative expression of the co-expression cluster over median <br>Analyst:

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Enriched sample ontology terms on this co-expression cluster<b>Summary:</b>To summarize promoter activities (expression profile of a TSS region) across ~1000 samples, we performed enrichment analysis based on FANTOM5 Sample Ontology (FF ontology). The question here is “in which type of samples the promoter is more active”. To answer this question, we compared expressions (TPMs) in the samples associated with a sample ontology term and the rest of the samples by using the Mann-Whitney rank sum test. To summarize ontologies enriched in this co-expression cluster, we ran the same analysis on an averaged expression profile of all promoters that make up. <b>Analyst:</b> Hideya Kawaji <br><br>links to source dataset<br><br><br>uberon_data<br><br>

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Uber Anatomy

Ontology term	p-value	n
intestine	1.36e-13	31
gastrointestinal system	9.31e-11	47
mucosa	2.35e-10	15
nervous system	2.20e-09	75
anatomical cluster	4.15e-09	244
intestinal mucosa	4.89e-09	13
anatomical wall	4.89e-09	13
wall of intestine	4.89e-09	13
gastrointestinal system mucosa	4.89e-09	13
central nervous system	5.33e-09	73
ectoderm-derived structure	6.64e-08	95
ectoderm	6.64e-08	95
presumptive ectoderm	6.64e-08	95
simple columnar epithelium	3.71e-07	11

TFBS overrepresentation<b>Summary:</b>The values shown are the p-values for overrepresentation of the motif in this coexpression cluster. So a small p-value means a strong overrepresentation. <b>Analyst:</b> Michiel de Hoon <br><br>link to source data <br> Novel motifs <br>data <br><br> Jaspar motifs <br>data

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Novel motifs

JASPAR motifs

Motifs	-log10(p-value)
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