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|ontology_enrichment_disease=
|ontology_enrichment_disease=
|ontology_enrichment_uberon=UBERON:0000160!2.36e-20!31;UBERON:0005409!2.77e-18!47;UBERON:0009854!5.14e-17!23;UBERON:0009856!5.14e-17!23;UBERON:0002107!2.07e-16!22;UBERON:0007499!2.07e-16!22;UBERON:0006925!2.07e-16!22;UBERON:0009497!2.07e-16!22;UBERON:0000015!2.07e-16!22;UBERON:0002423!2.07e-16!22;UBERON:0006235!2.07e-16!22;UBERON:0008835!2.07e-16!22;UBERON:0003894!2.07e-16!22;UBERON:0004161!2.07e-16!22;UBERON:0008836!2.07e-16!22;UBERON:0004119!5.82e-14!118;UBERON:0000925!5.82e-14!118;UBERON:0006595!5.82e-14!118;UBERON:0001007!1.92e-13!116;UBERON:0001555!1.92e-13!116;UBERON:0007026!1.92e-13!116;UBERON:0002365!2.21e-13!25;UBERON:0002330!2.21e-13!25;UBERON:0004921!2.27e-12!114;UBERON:0000344!5.46e-12!15;UBERON:0005172!5.88e-11!49;UBERON:0005173!5.88e-11!49;UBERON:0002417!5.88e-11!49;UBERON:0000916!5.88e-11!49;UBERON:0001242!1.30e-10!13;UBERON:0000060!1.30e-10!13;UBERON:0001262!1.30e-10!13;UBERON:0004786!1.30e-10!13;UBERON:0004923!7.41e-08!24;UBERON:0003929!9.54e-08!55;UBERON:0003350!2.15e-07!9;UBERON:0004808!2.15e-07!9;UBERON:0001277!2.15e-07!9;UBERON:0005256!6.11e-07!45
|ontology_enrichment_uberon=UBERON:0000160!2.36e-20!31;UBERON:0005409!2.77e-18!47;UBERON:0009854!5.14e-17!23;UBERON:0009856!5.14e-17!23;UBERON:0002107!2.07e-16!22;UBERON:0007499!2.07e-16!22;UBERON:0006925!2.07e-16!22;UBERON:0009497!2.07e-16!22;UBERON:0000015!2.07e-16!22;UBERON:0002423!2.07e-16!22;UBERON:0006235!2.07e-16!22;UBERON:0008835!2.07e-16!22;UBERON:0003894!2.07e-16!22;UBERON:0004161!2.07e-16!22;UBERON:0008836!2.07e-16!22;UBERON:0004119!5.82e-14!118;UBERON:0000925!5.82e-14!118;UBERON:0006595!5.82e-14!118;UBERON:0001007!1.92e-13!116;UBERON:0001555!1.92e-13!116;UBERON:0007026!1.92e-13!116;UBERON:0002365!2.21e-13!25;UBERON:0002330!2.21e-13!25;UBERON:0004921!2.27e-12!114;UBERON:0000344!5.46e-12!15;UBERON:0005172!5.88e-11!49;UBERON:0005173!5.88e-11!49;UBERON:0002417!5.88e-11!49;UBERON:0000916!5.88e-11!49;UBERON:0001242!1.30e-10!13;UBERON:0000060!1.30e-10!13;UBERON:0001262!1.30e-10!13;UBERON:0004786!1.30e-10!13;UBERON:0004923!7.41e-08!24;UBERON:0003929!9.54e-08!55;UBERON:0003350!2.15e-07!9;UBERON:0004808!2.15e-07!9;UBERON:0001277!2.15e-07!9;UBERON:0005256!6.11e-07!45
|tfbs_overrepresentation_for_novel_motifs=0.208476,0.0977083,0.168843,0.739325,0.888948,0.308414,0.112043,0.361174,0.404414,0.00350016,0.404613,0.253575,0.00828169,0.289429,0.752173,0,0.309914,0.0953118,0.743682,0.623202,0.0512113,0.633583,0.120443,0.189414,0.179859,0.142877,0.379306,0.584917,0.299612,0.392098,0.160881,0.438003,0.0925727,0.288802,0.0619493,0.104251,0.0129089,0.101007,0.637911,0.137541,0.641798,0.0628989,1.48349,0.0241935,0.0589518,0.260863,0.0617413,0.0167448,0.794042,0.476136,0.289608,0.377253,0.6126,0.642341,0.669172,0.300387,0.099563,0.0948438,0.335948,0.12502,0.131595,0.174379,1.29265,0.276815,0.135363,0.665433,0.334351,0.622543,0.405179,0.495496,0.00327076,0.101846,0.00412461,0.721623,0.000720129,0.641974,0.700008,0.0578435,0.388939,0.396041,0.922213,0.100711,1.51588,0.333264,0.186018,0.00287226,0.000527237,0.392943,0.847556,0.769078,0.387822,0.553554,0.149022,0.49526,0.11016,0.700476,1.56129,0.897646,0.0618303,0.974978,0.257782,1.38879,0.21512,0.606067,0.603918,0.0626689,0.360785,0.620555,0.131619,0.122646,0.561335,0.216259,0.241082,0.415911,0.393362,0.0979366,0.0532692,1.42764,0.0935714,0.247438,0.264184,0.0727123,0.0363578,0.798976,1.94929,0.786394,0.283214,0.875602,0.333215,0.211746,0.204392,1.0127,0.837339,0.137386,0.410485,0.0247547,0.104476,0.0636381,0.371824,1.11744,0.739864,0.896743,0.0395213,0.14775,0.281699,0.0631361,0.225295,1.07922,0.398635,0.107669,0.0106737,5.33301e-05,0.227379,0.392685,0.320334,0.773159,0.378971,0.146602,0.0321814,0.221675,0.988133,0.545061,0.394295,0.193854,0.0813638,0.564642,0.558405,0.472629,0.00885206
}}
}}

Revision as of 17:54, 26 November 2012


Phase1 CAGE Peaks

 Short description
Mm9::chr10:25255920..25255961,-p1@2010003K15Rik
Mm9::chr10:88969376..88969395,-p1@Nr1h4
Mm9::chr11:49058960..49059008,+p3@Mgat1
Mm9::chr11:51569880..51569995,-p1@Sec24a
Mm9::chr11:51577184..51577251,+p1@Sar1b
Mm9::chr11:77707345..77707356,-p2@Pipox
Mm9::chr11:78798336..78798425,-p1@Lgals9
Mm9::chr13:115608440..115608511,+p1@Mocs2
Mm9::chr13:41331391..41331435,+p@chr13:41331391..41331435
+
Mm9::chr13:41923683..41923694,-p4@9530008L14Rik
Mm9::chr13:41923706..41923771,-p1@9530008L14Rik
Mm9::chr13:41923787..41923813,-p3@9530008L14Rik
Mm9::chr14:123312330..123312412,-p1@A2ld1
Mm9::chr14:56377180..56377273,-p1@Cideb
Mm9::chr15:31498572..31498603,+p2@Cmbl
Mm9::chr15:31498606..31498680,+p1@Cmbl
Mm9::chr15:3220971..3221006,+p1@Sepp1
Mm9::chr15:75046595..75046610,-p@chr15:75046595..75046610
-
Mm9::chr15:82624697..82624714,-p3@Cyp2d26
Mm9::chr15:82624719..82624730,-p4@Cyp2d26
Mm9::chr15:98929918..98929955,+p1@Dnajc22
Mm9::chr16:21787869..21787886,-p1@Ehhadh
Mm9::chr16:22857509..22857535,-p4@Tbccd1
Mm9::chr16:38294929..38294940,-p2@Nr1i2
Mm9::chr17:33084295..33084313,-p2@Cyp4f13
Mm9::chr17:33084317..33084332,-p1@Cyp4f13
Mm9::chr18:11048648..11048660,-p@chr18:11048648..11048660
-
Mm9::chr18:11048665..11048683,-p@chr18:11048665..11048683
-
Mm9::chr18:35786860..35786876,-p3@Slc23a1
Mm9::chr19:33034620..33034661,+p@chr19:33034620..33034661
+
Mm9::chr19:43856787..43856803,+p1@Abcc2
Mm9::chr19:43856810..43856824,+p3@Abcc2
Mm9::chr19:43856829..43856840,+p4@Abcc2
Mm9::chr1:13658854..13658875,+p2@Xkr9
Mm9::chr1:13658880..13658893,+p3@Xkr9
Mm9::chr1:159456230..159456250,+p5@Sec16b
Mm9::chr1:173144100..173144138,+p2@Nr1i3
Mm9::chr1:89470400..89470446,-p2@Ngef
Mm9::chr2:110145776..110145800,-p5@Bbox1
Mm9::chr2:126969049..126969066,-p2@Itpripl1
Mm9::chr2:146839521..146839535,-p@chr2:146839521..146839535
-
Mm9::chr2:24935728..24935759,-p@chr2:24935728..24935759
-
Mm9::chr2:24935836..24935863,+p2@Entpd8
Mm9::chr3:10335676..10335687,-p2@Slc10a5
Mm9::chr3:10335689..10335707,-p1@Slc10a5
Mm9::chr3:28596868..28596902,+p1@Slc2a2
Mm9::chr4:106979733..106979766,-p1@Dio1
Mm9::chr4:117459895..117459906,+p@chr4:117459895..117459906
+
Mm9::chr4:118199591..118199629,+p4@2610528J11Rik
Mm9::chr4:118199638..118199669,+p3@2610528J11Rik
Mm9::chr4:35104653..35104749,-p1@Mob3b
Mm9::chr4:49493906..49493916,-p1@uc008svs.1
Mm9::chr4:49562357..49562386,-p1@Aldob
Mm9::chr4:49562395..49562410,-p2@Aldob
Mm9::chr6:115542589..115542617,-p1@2510049J12Rik
Mm9::chr6:137703050..137703120,+p1@Dera
Mm9::chr7:106331191..106331238,-p1@Dgat2
Mm9::chr7:127317416..127317428,+p2@Anks4b
Mm9::chr7:150659655..150659713,+p1@Slc22a18
Mm9::chr7:52830552..52830560,-p1@ENSMUST00000135933
Mm9::chr8:107450115..107450127,+p4@Ces2e
Mm9::chr8:113551570..113551621,-p3@Ddx19b
Mm9::chr8:120226089..120226100,+p@chr8:120226089..120226100
+
Mm9::chr8:73288050..73288083,-p@chr8:73288050..73288083
-
Mm9::chr9:103966046..103966066,+p1@Acad11
Mm9::chr9:44206450..44206477,+p3@Slc37a4


Enriched pathways on this co-expression cluster<b>Summary:</b><br>Canonical pathway gene sets were compiled from Reactome, Wikipathways and KEGG. For the major signaling pathways, the transcriptionally-regulated genes (downstream targets) were obtained from Netpath. Combined, the canonical pathways and downstream targets totaled 489 human gene sets. The corresponding M. musculus gene sets were inferred by homology using the HomoloGene database. Enrichment for each of the canonical 489 pathways and gene sets included in the co-expression cluster was assessed by the hypergeometric probability. The resulting P values were also then adjusted by the Benjamini-Hochberg method for multiple comparisons.<br><b>Analyst: </b>Emmanuel Dimont<br><br>link to source dataset<br>data

GO IDGO nameFDR corrected p-value
GO:0004144diacylglycerol O-acyltransferase activity0.00174125250254486
GO:0006639acylglycerol metabolic process0.00174125250254486
GO:0046486glycerolipid metabolic process0.00174125250254486
GO:0006638neutral lipid metabolic process0.00174125250254486
GO:0006662glycerol ether metabolic process0.00174125250254486
GO:00038462-acylglycerol O-acyltransferase activity0.00179856005864711
GO:0032787monocarboxylic acid metabolic process0.00374434532675187
GO:0046460neutral lipid biosynthetic process0.00374434532675187
GO:0016832aldehyde-lyase activity0.00374434532675187
GO:0046463acylglycerol biosynthetic process0.00374434532675187
GO:0046504glycerol ether biosynthetic process0.00374434532675187
GO:0045017glycerolipid biosynthetic process0.00374434532675187
GO:0016491oxidoreductase activity0.00374434532675187
GO:0003707steroid hormone receptor activity0.00374434532675187
GO:0004879ligand-dependent nuclear receptor activity0.00374434532675187
GO:0015293symporter activity0.00416216468050081
GO:0005624membrane fraction0.00667373808695119
GO:0016411acylglycerol O-acyltransferase activity0.00770460423265143
GO:0022804active transmembrane transporter activity0.00953023842497523
GO:0015291secondary active transmembrane transporter activity0.00953023842497523
GO:0000267cell fraction0.00953023842497523
GO:0044255cellular lipid metabolic process0.0101111549460318
GO:0006641triacylglycerol metabolic process0.0124823647578902
GO:0006071glycerol metabolic process0.0124823647578902
GO:0019751polyol metabolic process0.0124823647578902
GO:0042579microbody0.0124823647578902
GO:0005777peroxisome0.0124823647578902
GO:0006629lipid metabolic process0.0165168601474546
GO:0006091generation of precursor metabolites and energy0.0206997934162585
GO:0008374O-acyltransferase activity0.0212606019526577
GO:0008430selenium binding0.0212606019526577
GO:0009791post-embryonic development0.0212606019526577
GO:0019752carboxylic acid metabolic process0.0212606019526577
GO:0006082organic acid metabolic process0.0212606019526577
GO:0008115sarcosine oxidase activity0.0212606019526577
GO:0004139deoxyribose-phosphate aldolase activity0.0212606019526577
GO:0050031L-pipecolate oxidase activity0.0212606019526577
GO:0032682negative regulation of chemokine production0.0212606019526577
GO:0001887selenium metabolic process0.0212606019526577
GO:0008336gamma-butyrobetaine dioxygenase activity0.0212606019526577
GO:0046653tetrahydrofolate metabolic process0.0212606019526577
GO:0032642regulation of chemokine production0.0212606019526577
GO:0008520L-ascorbate:sodium symporter activity0.0212606019526577
GO:0005783endoplasmic reticulum0.0228979929338124
GO:0016830carbon-carbon lyase activity0.0269041737485365
GO:0015370solute:sodium symporter activity0.0291277756736434
GO:0016829lyase activity0.033874784032441
GO:0006118electron transport0.033874784032441
GO:0002318myeloid progenitor cell differentiation0.033874784032441
GO:0045730respiratory burst0.033874784032441
GO:0045329carnitine biosynthetic process0.033874784032441
GO:0006089lactate metabolic process0.033874784032441
GO:0035166post-embryonic hemopoiesis0.033874784032441
GO:0006732coenzyme metabolic process0.033874784032441
GO:0015294solute:cation symporter activity0.0407867671654657
GO:0016647oxidoreductase activity, acting on the CH-NH group of donors, oxygen as acceptor0.0434478032946142
GO:0050327testosterone 17-beta-dehydrogenase activity0.0434478032946142
GO:0012507ER to Golgi transport vesicle membrane0.0434478032946142
GO:0030134ER to Golgi transport vesicle0.0434478032946142
GO:0015760glucose-6-phosphate transport0.0434478032946142
GO:0030127COPII vesicle coat0.0434478032946142
GO:0004165dodecenoyl-CoA delta-isomerase activity0.0434478032946142
GO:0004800thyroxine 5'-deiodinase activity0.0434478032946142
GO:0051186cofactor metabolic process0.0446139464425043
GO:0044249cellular biosynthetic process0.0446139464425043
GO:0006790sulfur metabolic process0.0449109058718855
GO:0008643carbohydrate transport0.0471450283721544
GO:0009058biosynthetic process0.0472297746847424
GO:0019432triacylglycerol biosynthetic process0.0479739257451353
GO:0009133nucleoside diphosphate biosynthetic process0.0479739257451353
GO:0001780neutrophil homeostasis0.0479739257451353
GO:0006651diacylglycerol biosynthetic process0.0479739257451353
GO:0009437carnitine metabolic process0.0479739257451353
GO:0004300enoyl-CoA hydratase activity0.0479739257451353
GO:00038573-hydroxyacyl-CoA dehydrogenase activity0.0479739257451353
GO:0009264deoxyribonucleotide catabolic process0.0479739257451353



Relative expression of the co-expression cluster over median <br>Analyst:




Enriched sample ontology terms on this co-expression cluster<b>Summary:</b>To summarize promoter activities (expression profile of a TSS region) across ~1000 samples, we performed enrichment analysis based on FANTOM5 Sample Ontology (FF ontology). The question here is “in which type of samples the promoter is more active”. To answer this question, we compared expressions (TPMs) in the samples associated with a sample ontology term and the rest of the samples by using the Mann-Whitney rank sum test. To summarize ontologies enriched in this co-expression cluster, we ran the same analysis on an averaged expression profile of all promoters that make up. <b>Analyst:</b> Hideya Kawaji <br><br>links to source dataset<br><br>cell_data<br>uberon_data<br><br>

Cell Type
Ontology termp-valuen
intestinal epithelial cell2.15e-079
epithelial cell of alimentary canal2.15e-079
epithelial cell5.62e-0725

Uber Anatomy
Ontology termp-valuen
intestine2.36e-2031
gastrointestinal system2.77e-1847
digestive tract diverticulum5.14e-1723
sac5.14e-1723
liver2.07e-1622
epithelial sac2.07e-1622
digestive gland2.07e-1622
epithelium of foregut-midgut junction2.07e-1622
anatomical boundary2.07e-1622
hepatobiliary system2.07e-1622
foregut-midgut junction2.07e-1622
hepatic diverticulum2.07e-1622
liver primordium2.07e-1622
septum transversum2.07e-1622
liver bud2.07e-1622
endoderm-derived structure5.82e-14118
endoderm5.82e-14118
presumptive endoderm5.82e-14118
digestive system1.92e-13116
digestive tract1.92e-13116
primitive gut1.92e-13116
exocrine gland2.21e-1325
exocrine system2.21e-1325
subdivision of digestive tract2.27e-12114
mucosa5.46e-1215
abdomen element5.88e-1149
abdominal segment element5.88e-1149
abdominal segment of trunk5.88e-1149
abdomen5.88e-1149
intestinal mucosa1.30e-1013
anatomical wall1.30e-1013
wall of intestine1.30e-1013
gastrointestinal system mucosa1.30e-1013
organ component layer7.41e-0824
gut epithelium9.54e-0855
epithelium of mucosa2.15e-079
gastrointestinal system epithelium2.15e-079
intestinal epithelium2.15e-079
trunk mesenchyme6.11e-0745


TFBS overrepresentation<b>Summary:</b>The values shown are the p-values for overrepresentation of the motif in this coexpression cluster. So a small p-value means a strong overrepresentation. <b>Analyst:</b> Michiel de Hoon <br><br>link to source data <br> Novel motifs <br>data <br><br> Jaspar motifs <br>data

Novel motifs




JASPAR motifs


Motifs-log10(p-value)

{{{tfbs_overrepresentation_jaspar}}}

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