MCL coexpression mm9:2905: Difference between revisions
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|ontology_enrichment_uberon=UBERON:0000468!8.90e-07!333 | |ontology_enrichment_uberon=UBERON:0000468!8.90e-07!333 | ||
|tfbs_overrepresentation_for_novel_motifs=1.77936,0.193418,0.722405,0.801166,0.587814,0.81763,0.919454,0.467321,0.479531,1.23467,0.870507,0.906098,0.467629,0.933025,0.608226,0,1.14208,0.578045,0.448066,0.328717,0.679146,0.275782,0.932027,0.585919,0.731217,0.963352,0.437236,0.841386,0.64294,0.380786,0.825437,1.24901,0.575271,1.05917,0.608816,2.02463,1.38481,0.902078,0.536514,3.19233,0.582863,0.831295,0.261619,0.610669,0.922882,0.788421,1.05665,0.859154,0.235354,0.646474,1.12346,0.99279,0.371606,1.3966,1.41464,0.940919,0.657156,0.891887,0.425455,0.938668,1.22795,1.00308,0.494668,1.11142,0.953187,1.15459,1.55483,1.90983,1.22303,1.7608,0.700291,0.474956,1.41919,1.44925,1.07031,1.03818,0.411601,1.04436,1.20986,0.684144,0.476502,1.16055,1.00151,0.459035,1.32978,3.89074,0.195254,0.99201,1.06194,2.07346,1.62608,1.33496,1.26245,0.595071,1.31639,0.509215,0.464141,1.26539,1.05692,0.352122,0.563856,1.24872,1.37854,1.12409,1.12297,0.830796,1.18646,0.854628,0.689894,0.681267,0.744607,1.38039,0.685481,0.876299,1.63327,0.580657,0.609576,0.805461,1.14346,1.37508,1.45481,1.08896,0.965352,1.04338,1.68841,1.21376,0.928483,1.25534,1.55328,0.598722,1.36093,0.792832,1.52297,0.955954,1.65529,0.273451,0.762499,0.832891,1.60513,2.44352,2.04137,1.55966,0.978551,1.26,1.11604,0.831808,1.06002,2.40374,0.765221,0.589976,2.65814,3.74474,1.39822,0.516739,0.954936,1.48249,0.993889,0.622823,0.749933,0.762177,1.61484,1.32889,1.21423,0.741984,1.11251,0.94678,0.562367,0.904334,3.36183 | |tfbs_overrepresentation_for_novel_motifs=1.77936,0.193418,0.722405,0.801166,0.587814,0.81763,0.919454,0.467321,0.479531,1.23467,0.870507,0.906098,0.467629,0.933025,0.608226,0,1.14208,0.578045,0.448066,0.328717,0.679146,0.275782,0.932027,0.585919,0.731217,0.963352,0.437236,0.841386,0.64294,0.380786,0.825437,1.24901,0.575271,1.05917,0.608816,2.02463,1.38481,0.902078,0.536514,3.19233,0.582863,0.831295,0.261619,0.610669,0.922882,0.788421,1.05665,0.859154,0.235354,0.646474,1.12346,0.99279,0.371606,1.3966,1.41464,0.940919,0.657156,0.891887,0.425455,0.938668,1.22795,1.00308,0.494668,1.11142,0.953187,1.15459,1.55483,1.90983,1.22303,1.7608,0.700291,0.474956,1.41919,1.44925,1.07031,1.03818,0.411601,1.04436,1.20986,0.684144,0.476502,1.16055,1.00151,0.459035,1.32978,3.89074,0.195254,0.99201,1.06194,2.07346,1.62608,1.33496,1.26245,0.595071,1.31639,0.509215,0.464141,1.26539,1.05692,0.352122,0.563856,1.24872,1.37854,1.12409,1.12297,0.830796,1.18646,0.854628,0.689894,0.681267,0.744607,1.38039,0.685481,0.876299,1.63327,0.580657,0.609576,0.805461,1.14346,1.37508,1.45481,1.08896,0.965352,1.04338,1.68841,1.21376,0.928483,1.25534,1.55328,0.598722,1.36093,0.792832,1.52297,0.955954,1.65529,0.273451,0.762499,0.832891,1.60513,2.44352,2.04137,1.55966,0.978551,1.26,1.11604,0.831808,1.06002,2.40374,0.765221,0.589976,2.65814,3.74474,1.39822,0.516739,0.954936,1.48249,0.993889,0.622823,0.749933,0.762177,1.61484,1.32889,1.21423,0.741984,1.11251,0.94678,0.562367,0.904334,3.36183 | ||
|tfbs_overrepresentation_jaspar=MA0003.1;1.87396,MA0004.1;0.801718,MA0006.1;1.46714,MA0007.1;0.784593,MA0009.1;1.27673,MA0014.1;2.60474,MA0017.1;0.635031,MA0019.1;1.08369,MA0024.1;1.23079,MA0025.1;1.51835,MA0027.1;2.9431,MA0028.1;0.61552,MA0029.1;1.20789,MA0030.1;1.21482,MA0031.1;1.17722,MA0038.1;0.963265,MA0040.1;1.28983,MA0041.1;0.714279,MA0042.1;0.69885,MA0043.1;1.3775,MA0046.1;1.31428,MA0048.1;0.932001,MA0050.1;0.845669,MA0051.1;0.973068,MA0052.1;1.29825,MA0055.1;0.190475,MA0056.1;0,MA0057.1;2.43475,MA0058.1;0.690848,MA0059.1;0.705317,MA0060.1;0.502699,MA0061.1;0.5406,MA0063.1;0,MA0066.1;0.951196,MA0067.1;1.63197,MA0068.1;0.343188,MA0069.1;1.29861,MA0070.1;1.28847,MA0071.1;0.844726,MA0072.1;1.2796,MA0073.1;0.25258,MA0074.1;0.911576,MA0076.1;0.657929,MA0077.1;1.2569,MA0078.1;1.0091,MA0081.1;0.732313,MA0083.1;1.37668,MA0084.1;1.96428,MA0087.1;1.33189,MA0088.1;1.40099,MA0089.1;0,MA0090.1;1.7994,MA0091.1;0.816659,MA0092.1;0.762845,MA0093.1;0.62555,MA0095.1;0,MA0098.1;0,MA0100.1;0.89873,MA0101.1;0.71579,MA0103.1;0.647985,MA0105.1;1.04599,MA0106.1;1.01755,MA0107.1;0.640607,MA0108.2;1.10817,MA0109.1;0,MA0111.1;0.778753,MA0113.1;0.986839,MA0114.1;0.537669,MA0115.1;1.38041,MA0116.1;0.602598,MA0117.1;2.98823,MA0119.1;0.716476,MA0122.1;1.36752,MA0124.1;1.57762,MA0125.1;1.5017,MA0130.1;0,MA0131.1;2.44622,MA0132.1;0,MA0133.1;0,MA0135.1;1.4152,MA0136.1;0.933582,MA0139.1;0.462282,MA0140.1;0.898603,MA0141.1;0.671467,MA0142.1;1.16183,MA0143.1;1.00467,MA0144.1;0.541532,MA0145.1;0.292366,MA0146.1;4.37098,MA0147.1;0.556853,MA0148.1;0.820161,MA0149.1;0.722227,MA0062.2;1.86813,MA0035.2;0.903829,MA0039.2;3.25387,MA0138.2;1.07027,MA0002.2;0.466067,MA0137.2;0.668025,MA0104.2;0.48458,MA0047.2;0.962424,MA0112.2;0.29236,MA0065.2;1.44804,MA0150.1;0.784464,MA0151.1;0,MA0152.1;0.962542,MA0153.1;1.43238,MA0154.1;0.35067,MA0155.1;0.312898,MA0156.1;0.656895,MA0157.1;1.12772,MA0158.1;0,MA0159.1;0.569393,MA0160.1;0.823568,MA0161.1;0,MA0162.1;7.41514,MA0163.1;0.927936,MA0164.1;0.933981,MA0080.2;0.64167,MA0018.2;0.944669,MA0099.2;1.06348,MA0079.2;7.3104,MA0102.2;2.01714,MA0258.1;0.520639,MA0259.1;0.543506,MA0442.1;0 | |||
}} | }} |
Revision as of 15:33, 23 January 2013
Phase1 CAGE Peaks
Short description | |
---|---|
Mm9::chr14:35315849..35315901,- | p2@Bmpr1a |
Mm9::chr8:131209774..131209811,+ | p3@Itgb1 |
Mm9::chr8:131209812..131209823,+ | p4@Itgb1 |
Enriched pathways on this co-expression cluster<b>Summary:</b><br>Canonical pathway gene sets were compiled from Reactome, Wikipathways and KEGG. For the major signaling pathways, the transcriptionally-regulated genes (downstream targets) were obtained from Netpath. Combined, the canonical pathways and downstream targets totaled 489 human gene sets. The corresponding M. musculus gene sets were inferred by homology using the HomoloGene database. Enrichment for each of the canonical 489 pathways and gene sets included in the co-expression cluster was assessed by the hypergeometric probability. The resulting P values were also then adjusted by the Benjamini-Hochberg method for multiple comparisons.<br><b>Analyst: </b>Emmanuel Dimont<br><br>link to source dataset<br>data
GO ID | GO name | FDR corrected p-value |
---|---|---|
GO:0007507 | heart development | 0.00314103617670155 |
GO:0008284 | positive regulation of cell proliferation | 0.00314103617670155 |
GO:0042684 | cardioblast cell fate commitment | 0.00314103617670155 |
GO:0042685 | cardioblast cell fate specification | 0.00314103617670155 |
GO:0048382 | mesendoderm development | 0.00314103617670155 |
GO:0001880 | Mullerian duct regression | 0.00314103617670155 |
GO:0042127 | regulation of cell proliferation | 0.00628172816797938 |
GO:0010002 | cardioblast differentiation | 0.00628172816797938 |
GO:0060033 | anatomical structure regression | 0.00628172816797938 |
GO:0009950 | dorsal/ventral axis specification | 0.00753786729032103 |
GO:0008283 | cell proliferation | 0.00999617726056794 |
GO:0045214 | sarcomere organization | 0.0134564208330796 |
GO:0004675 | transmembrane receptor protein serine/threonine kinase activity | 0.0134564208330796 |
GO:0005024 | transforming growth factor beta receptor activity | 0.0134564208330796 |
GO:0031594 | neuromuscular junction | 0.0134564208330796 |
GO:0030239 | myofibril assembly | 0.0134564208330796 |
GO:0055002 | striated muscle cell development | 0.0134564208330796 |
GO:0048522 | positive regulation of cellular process | 0.0134564208330796 |
GO:0050679 | positive regulation of epithelial cell proliferation | 0.0134564208330796 |
GO:0055001 | muscle cell development | 0.0134564208330796 |
GO:0035051 | cardiac cell differentiation | 0.0134564208330796 |
GO:0009798 | axis specification | 0.0139237070595951 |
GO:0007492 | endoderm development | 0.0139237070595951 |
GO:0048518 | positive regulation of biological process | 0.0141257569973187 |
GO:0031032 | actomyosin structure organization and biogenesis | 0.0141257569973187 |
GO:0048628 | myoblast maturation | 0.0141257569973187 |
GO:0048627 | myoblast development | 0.0141257569973187 |
GO:0005178 | integrin binding | 0.0141257569973187 |
GO:0035137 | hindlimb morphogenesis | 0.0141257569973187 |
GO:0001708 | cell fate specification | 0.0141257569973187 |
GO:0050678 | regulation of epithelial cell proliferation | 0.0141257569973187 |
GO:0000082 | G1/S transition of mitotic cell cycle | 0.0141257569973187 |
GO:0046661 | male sex differentiation | 0.0154086494961967 |
GO:0042383 | sarcolemma | 0.0155089344533936 |
GO:0051146 | striated muscle cell differentiation | 0.01560345934 |
GO:0050673 | epithelial cell proliferation | 0.0162153497277896 |
GO:0008305 | integrin complex | 0.0173024896210547 |
GO:0045445 | myoblast differentiation | 0.0178371922030721 |
GO:0051325 | interphase | 0.0192962050831568 |
GO:0051329 | interphase of mitotic cell cycle | 0.0192962050831568 |
GO:0009953 | dorsal/ventral pattern formation | 0.0197428032994193 |
GO:0004702 | receptor signaling protein serine/threonine kinase activity | 0.020048920647292 |
GO:0048513 | organ development | 0.020048920647292 |
GO:0051216 | cartilage development | 0.020048920647292 |
GO:0007498 | mesoderm development | 0.020048920647292 |
GO:0032403 | protein complex binding | 0.020048920647292 |
GO:0019717 | synaptosome | 0.0208220025003276 |
GO:0042692 | muscle cell differentiation | 0.0225101491194736 |
GO:0007160 | cell-matrix adhesion | 0.0225101491194736 |
GO:0048741 | skeletal muscle fiber development | 0.0225101491194736 |
GO:0030324 | lung development | 0.0225101491194736 |
GO:0048747 | muscle fiber development | 0.0225101491194736 |
GO:0030323 | respiratory tube development | 0.0225101491194736 |
GO:0031589 | cell-substrate adhesion | 0.0225101491194736 |
GO:0043235 | receptor complex | 0.0225101491194736 |
GO:0019199 | transmembrane receptor protein kinase activity | 0.0225101491194736 |
GO:0007548 | sex differentiation | 0.0225101491194736 |
GO:0048731 | system development | 0.0225101491194736 |
GO:0048469 | cell maturation | 0.0225101491194736 |
GO:0035107 | appendage morphogenesis | 0.0225101491194736 |
GO:0035108 | limb morphogenesis | 0.0225101491194736 |
GO:0048869 | cellular developmental process | 0.0225101491194736 |
GO:0030154 | cell differentiation | 0.0225101491194736 |
GO:0060173 | limb development | 0.0225101491194736 |
GO:0048736 | appendage development | 0.0225101491194736 |
GO:0007178 | transmembrane receptor protein serine/threonine kinase signaling pathway | 0.0225101491194736 |
GO:0045596 | negative regulation of cell differentiation | 0.0234347923769146 |
GO:0005057 | receptor signaling protein activity | 0.0234347923769146 |
GO:0003006 | reproductive developmental process | 0.0234347923769146 |
GO:0007229 | integrin-mediated signaling pathway | 0.0240954568246319 |
GO:0021700 | developmental maturation | 0.0240954568246319 |
GO:0009952 | anterior/posterior pattern formation | 0.0244627432461561 |
GO:0007519 | skeletal muscle development | 0.0244627432461561 |
GO:0048856 | anatomical structure development | 0.0249770199198955 |
GO:0045165 | cell fate commitment | 0.0249770199198955 |
GO:0007398 | ectoderm development | 0.0249770199198955 |
GO:0051093 | negative regulation of developmental process | 0.0253828078295289 |
GO:0001701 | in utero embryonic development | 0.0286596186228907 |
GO:0014706 | striated muscle development | 0.0290078124494747 |
GO:0007275 | multicellular organismal development | 0.029292524320212 |
GO:0030145 | manganese ion binding | 0.0299091014344784 |
GO:0003002 | regionalization | 0.033650165201287 |
GO:0045595 | regulation of cell differentiation | 0.0344065819266945 |
GO:0030036 | actin cytoskeleton organization and biogenesis | 0.0344065819266945 |
GO:0030029 | actin filament-based process | 0.0358386395598984 |
GO:0007517 | muscle development | 0.0358386395598984 |
GO:0007166 | cell surface receptor linked signal transduction | 0.0358386395598984 |
GO:0001501 | skeletal development | 0.0383600521512519 |
GO:0035295 | tube development | 0.0423296095286837 |
GO:0022414 | reproductive process | 0.0428946476526525 |
GO:0004872 | receptor activity | 0.0435784814301501 |
GO:0032502 | developmental process | 0.0441059329296329 |
GO:0043009 | chordate embryonic development | 0.044165931537471 |
GO:0009792 | embryonic development ending in birth or egg hatching | 0.044165931537471 |
GO:0000278 | mitotic cell cycle | 0.044165931537471 |
GO:0007389 | pattern specification process | 0.0456444403706497 |
GO:0004871 | signal transducer activity | 0.0467989271816792 |
GO:0060089 | molecular transducer activity | 0.0467989271816792 |
GO:0050793 | regulation of developmental process | 0.0483932215224717 |
GO:0007167 | enzyme linked receptor protein signaling pathway | 0.0497670129224057 |
GO:0022403 | cell cycle phase | 0.0498889685485099 |
GO:0050794 | regulation of cellular process | 0.0498889685485099 |
Relative expression of the co-expression cluster over median <br>Analyst:
Enriched sample ontology terms on this co-expression cluster<b>Summary:</b>To summarize promoter activities (expression profile of a TSS region) across ~1000 samples, we performed enrichment analysis based on FANTOM5 Sample Ontology (FF ontology). The question here is “in which type of samples the promoter is more active”. To answer this question, we compared expressions (TPMs) in the samples associated with a sample ontology term and the rest of the samples by using the Mann-Whitney rank sum test. To summarize ontologies enriched in this co-expression cluster, we ran the same analysis on an averaged expression profile of all promoters that make up. <b>Analyst:</b> Hideya Kawaji <br><br>links to source dataset<br><br><br>uberon_data<br><br>
Ontology term | p-value | n |
---|---|---|
multi-cellular organism | 8.90e-07 | 333 |
TFBS overrepresentation<b>Summary:</b>The values shown are the p-values for overrepresentation of the motif in this coexpression cluster. So a small p-value means a strong overrepresentation. <b>Analyst:</b> Michiel de Hoon <br><br>link to source data <br> Novel motifs <br>data <br><br> Jaspar motifs <br>data
Novel motifs
JASPAR motifs
Motifs | -log10(p-value) |
---|---|
MA0003.1 | 1.87396 |
MA0004.1 | 0.801718 |
MA0006.1 | 1.46714 |
MA0007.1 | 0.784593 |
MA0009.1 | 1.27673 |
MA0014.1 | 2.60474 |
MA0017.1 | 0.635031 |
MA0019.1 | 1.08369 |
MA0024.1 | 1.23079 |
MA0025.1 | 1.51835 |
MA0027.1 | 2.9431 |
MA0028.1 | 0.61552 |
MA0029.1 | 1.20789 |
MA0030.1 | 1.21482 |
MA0031.1 | 1.17722 |
MA0038.1 | 0.963265 |
MA0040.1 | 1.28983 |
MA0041.1 | 0.714279 |
MA0042.1 | 0.69885 |
MA0043.1 | 1.3775 |
MA0046.1 | 1.31428 |
MA0048.1 | 0.932001 |
MA0050.1 | 0.845669 |
MA0051.1 | 0.973068 |
MA0052.1 | 1.29825 |
MA0055.1 | 0.190475 |
MA0056.1 | 0 |
MA0057.1 | 2.43475 |
MA0058.1 | 0.690848 |
MA0059.1 | 0.705317 |
MA0060.1 | 0.502699 |
MA0061.1 | 0.5406 |
MA0063.1 | 0 |
MA0066.1 | 0.951196 |
MA0067.1 | 1.63197 |
MA0068.1 | 0.343188 |
MA0069.1 | 1.29861 |
MA0070.1 | 1.28847 |
MA0071.1 | 0.844726 |
MA0072.1 | 1.2796 |
MA0073.1 | 0.25258 |
MA0074.1 | 0.911576 |
MA0076.1 | 0.657929 |
MA0077.1 | 1.2569 |
MA0078.1 | 1.0091 |
MA0081.1 | 0.732313 |
MA0083.1 | 1.37668 |
MA0084.1 | 1.96428 |
MA0087.1 | 1.33189 |
MA0088.1 | 1.40099 |
MA0089.1 | 0 |
MA0090.1 | 1.7994 |
MA0091.1 | 0.816659 |
MA0092.1 | 0.762845 |
MA0093.1 | 0.62555 |
MA0095.1 | 0 |
MA0098.1 | 0 |
MA0100.1 | 0.89873 |
MA0101.1 | 0.71579 |
MA0103.1 | 0.647985 |
MA0105.1 | 1.04599 |
MA0106.1 | 1.01755 |
MA0107.1 | 0.640607 |
MA0108.2 | 1.10817 |
MA0109.1 | 0 |
MA0111.1 | 0.778753 |
MA0113.1 | 0.986839 |
MA0114.1 | 0.537669 |
MA0115.1 | 1.38041 |
MA0116.1 | 0.602598 |
MA0117.1 | 2.98823 |
MA0119.1 | 0.716476 |
MA0122.1 | 1.36752 |
MA0124.1 | 1.57762 |
MA0125.1 | 1.5017 |
MA0130.1 | 0 |
MA0131.1 | 2.44622 |
MA0132.1 | 0 |
MA0133.1 | 0 |
MA0135.1 | 1.4152 |
MA0136.1 | 0.933582 |
MA0139.1 | 0.462282 |
MA0140.1 | 0.898603 |
MA0141.1 | 0.671467 |
MA0142.1 | 1.16183 |
MA0143.1 | 1.00467 |
MA0144.1 | 0.541532 |
MA0145.1 | 0.292366 |
MA0146.1 | 4.37098 |
MA0147.1 | 0.556853 |
MA0148.1 | 0.820161 |
MA0149.1 | 0.722227 |
MA0062.2 | 1.86813 |
MA0035.2 | 0.903829 |
MA0039.2 | 3.25387 |
MA0138.2 | 1.07027 |
MA0002.2 | 0.466067 |
MA0137.2 | 0.668025 |
MA0104.2 | 0.48458 |
MA0047.2 | 0.962424 |
MA0112.2 | 0.29236 |
MA0065.2 | 1.44804 |
MA0150.1 | 0.784464 |
MA0151.1 | 0 |
MA0152.1 | 0.962542 |
MA0153.1 | 1.43238 |
MA0154.1 | 0.35067 |
MA0155.1 | 0.312898 |
MA0156.1 | 0.656895 |
MA0157.1 | 1.12772 |
MA0158.1 | 0 |
MA0159.1 | 0.569393 |
MA0160.1 | 0.823568 |
MA0161.1 | 0 |
MA0162.1 | 7.41514 |
MA0163.1 | 0.927936 |
MA0164.1 | 0.933981 |
MA0080.2 | 0.64167 |
MA0018.2 | 0.944669 |
MA0099.2 | 1.06348 |
MA0079.2 | 7.3104 |
MA0102.2 | 2.01714 |
MA0258.1 | 0.520639 |
MA0259.1 | 0.543506 |
MA0442.1 | 0 |