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MCL coexpression mm9:1078: Difference between revisions

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{{MCL_coexpression_mm9
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binding;0.0111756326709401;17304!GO:0001786;phosphatidylserine binding;0.0111756326709401;17304!GO:0006910;phagocytosis, recognition;0.0198607156030382;17304!GO:0006911;phagocytosis, engulfment;0.0198607156030382;17304!GO:0050766;positive regulation of phagocytosis;0.0198607156030382;17304!GO:0050764;regulation of phagocytosis;0.0198607156030382;17304!GO:0045807;positive regulation of endocytosis;0.0204779951512838;17304!GO:0005178;integrin binding;0.0204779951512838;17304!GO:0009408;response to heat;0.0206689683680001;12406!GO:0051050;positive regulation of transport;0.0206689683680001;17304!GO:0030100;regulation of endocytosis;0.0206689683680001;17304!GO:0006909;phagocytosis;0.0206689683680001;17304!GO:0007338;single fertilization;0.0206689683680001;17304!GO:0008037;cell recognition;0.0206689683680001;17304!GO:0009266;response to temperature stimulus;0.0206689683680001;12406!GO:0009566;fertilization;0.0206689683680001;17304!GO:0032403;protein complex binding;0.0206689683680001;17304!GO:0019897;extrinsic to plasma membrane;0.0206689683680001;17304!GO:0051082;unfolded protein binding;0.0227091238159021;12406!GO:0019898;extrinsic to membrane;0.025657479305141;17304!GO:0051049;regulation of transport;0.0297355554952831;17304!GO:0004867;serine-type endopeptidase inhibitor activity;0.034112378156982;12406!GO:0005615;extracellular space;0.0344229673627489;17304,12406!GO:0044421;extracellular region part;0.0370600414302398;17304,12406!GO:0009897;external side of plasma membrane;0.0401296360079547;17304!GO:0004866;endopeptidase inhibitor activity;0.0401296360079547;12406!GO:0030414;protease inhibitor activity;0.0401296360079547;12406!GO:0010324;membrane invagination;0.0415337643679454;17304!GO:0006897;endocytosis;0.0415337643679454;17304!GO:0009628;response to abiotic stimulus;0.0415337643679454;12406!GO:0009986;cell surface;0.0442405047433432;17304!GO:0005543;phospholipid binding;0.0448897475434736;17304!GO:0022414;reproductive process;0.0448897475434736;17304!GO:0004857;enzyme inhibitor activity;0.0448897475434736;12406!GO:0016044;membrane organization and 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|gostat_on_MCL_coexpression=GO:0008429;phosphatidylethanolamine binding;0.0111756326709401;17304!GO:0001786;phosphatidylserine binding;0.0111756326709401;17304!GO:0006910;phagocytosis, recognition;0.0198607156030382;17304!GO:0006911;phagocytosis, engulfment;0.0198607156030382;17304!GO:0050766;positive regulation of phagocytosis;0.0198607156030382;17304!GO:0050764;regulation of phagocytosis;0.0198607156030382;17304!GO:0045807;positive regulation of endocytosis;0.0204779951512838;17304!GO:0005178;integrin binding;0.0204779951512838;17304!GO:0009408;response to heat;0.0206689683680001;12406!GO:0051050;positive regulation of transport;0.0206689683680001;17304!GO:0030100;regulation of endocytosis;0.0206689683680001;17304!GO:0006909;phagocytosis;0.0206689683680001;17304!GO:0007338;single fertilization;0.0206689683680001;17304!GO:0008037;cell recognition;0.0206689683680001;17304!GO:0009266;response to temperature stimulus;0.0206689683680001;12406!GO:0009566;fertilization;0.0206689683680001;17304!GO:0032403;protein complex binding;0.0206689683680001;17304!GO:0019897;extrinsic to plasma membrane;0.0206689683680001;17304!GO:0051082;unfolded protein binding;0.0227091238159021;12406!GO:0019898;extrinsic to membrane;0.025657479305141;17304!GO:0051049;regulation of transport;0.0297355554952831;17304!GO:0004867;serine-type endopeptidase inhibitor activity;0.034112378156982;12406!GO:0005615;extracellular space;0.0344229673627489;17304,12406!GO:0044421;extracellular region part;0.0370600414302398;17304,12406!GO:0009897;external side of plasma membrane;0.0401296360079547;17304!GO:0004866;endopeptidase inhibitor activity;0.0401296360079547;12406!GO:0030414;protease inhibitor activity;0.0401296360079547;12406!GO:0010324;membrane invagination;0.0415337643679454;17304!GO:0006897;endocytosis;0.0415337643679454;17304!GO:0009628;response to abiotic stimulus;0.0415337643679454;12406!GO:0009986;cell surface;0.0442405047433432;17304!GO:0005543;phospholipid binding;0.0448897475434736;17304!GO:0022414;reproductive process;0.0448897475434736;17304!GO:0004857;enzyme inhibitor activity;0.0448897475434736;12406!GO:0016044;membrane organization and biogenesis;0.0492860006314063;17304!
|ontology_enrichment_celltype=CL:0000055!1.25e-07!49;CL:0000333!4.41e-07!10;CL:0000095!4.41e-07!10;CL:0000243!4.41e-07!10;CL:0000123!4.41e-07!10;CL:0000125!4.41e-07!10;CL:0000030!4.41e-07!10;CL:0000339!4.41e-07!10
|ontology_enrichment_disease=
|ontology_enrichment_uberon=
|tfbs_overrepresentation_for_novel_motifs=1.95401,0.161863,1.05921,0.480627,0.810002,0.495263,0.587291,0.206208,0.616096,0.826837,0.542749,0.575086,0.59526,0.599731,0.847296,0,0.795315,0.291368,0.561256,0.361892,0.374752,1.47264,1.45867,0.29769,0.419327,1.51917,0.184473,0.516511,0.344372,0.876948,0.50223,0.897561,0.289148,0.166577,0.848378,0.248902,0.766323,0.57142,0.258564,2.65781,0.295233,1.26538,0.932136,0.317766,0.277561,1.18381,0.714592,0.532496,0.478447,0.347313,0.777641,0.654933,0.851157,1.04034,1.0579,0.606984,0.356236,0.56214,0.522357,0.604914,0.877332,0.664501,0.226529,0.766235,0.618279,0.807219,1.19497,1.54543,0.872612,1.39786,1.79967,0.21183,0.0869413,1.09164,1.55661,0.482617,0.498755,0.703064,0.859987,0.378988,0.212973,0.812889,0.663039,0.580284,0.975495,0.613286,0.164297,0.145788,0.719558,1.70793,1.26498,0.980512,0.910485,0.305079,0.254625,0.237542,0.203879,0.913319,0.71485,0.127063,0.7665,0.897279,1.02279,0.778243,0.777175,1.26443,0.837607,0.528416,0.383871,0.376549,0.430942,1.02459,0.380122,0.547992,1.27206,0.796976,3.30647,0.484437,0.796633,1.38758,1.09707,1.76329,0.629509,0.702145,1.32639,0.863723,0.595563,0.903645,1.19345,0.829907,1.00568,0.473246,1.16374,0.620831,1.29374,0.0806013,0.446555,0.508896,1.24438,2.07659,1.67603,1.19971,0.641722,0.908128,0.770616,0.507927,0.717753,2.03691,1.13988,1.47713,1.42503,0.0736236,2.37131,0.243291,0.619892,1.12411,0.655955,0.327731,0.435579,0.446272,1.25393,0.974632,0.864173,0.428662,0.767269,0.612377,0.278874,0.573477,1.86859
|tfbs_overrepresentation_jaspar=MA0003.1;0.0861444,MA0004.1;0.481116,MA0006.1;0.311391,MA0007.1;0.465969,MA0009.1;0.92425,MA0014.1;0.0886247,MA0017.1;0.89657,MA0019.1;0.740036,MA0024.1;0.880057,MA0025.1;1.15921,MA0027.1;2.57545,MA0028.1;0.321735,MA0029.1;0.858105,MA0030.1;0.864739,MA0031.1;0.828781,MA0038.1;0.62758,MA0040.1;0.936879,MA0041.1;0.404721,MA0042.1;0.391504,MA0043.1;1.02178,MA0046.1;0.960497,MA0048.1;2.54841,MA0050.1;0.520357,MA0051.1;0.636645,MA0052.1;0.945011,MA0055.1;0.0406078,MA0056.1;0,MA0057.1;0.117936,MA0058.1;0.384683,MA0059.1;1.02718,MA0060.1;0.232592,MA0061.1;0.261749,MA0063.1;0,MA0066.1;0.616444,MA0067.1;1.27078,MA0068.1;0.771749,MA0069.1;0.945354,MA0070.1;0.93557,MA0071.1;1.29103,MA0072.1;0.927016,MA0073.1;0.00782298,MA0074.1;0.580087,MA0076.1;0.356883,MA0077.1;0.905143,MA0078.1;0.670113,MA0081.1;0.420276,MA0083.1;1.02098,MA0084.1;1.59945,MA0087.1;0.977537,MA0088.1;0.598004,MA0089.1;0,MA0090.1;0.446539,MA0091.1;0.494398,MA0092.1;0.446857,MA0093.1;0.879104,MA0095.1;0,MA0098.1;0,MA0100.1;0.568369,MA0101.1;0.406019,MA0103.1;0.348572,MA0105.1;0.488671,MA0106.1;0.677988,MA0107.1;0.342432,MA0108.2;0.763162,MA0109.1;0,MA0111.1;0.460823,MA0113.1;0.649407,MA0114.1;2.04376,MA0115.1;1.0246,MA0116.1;0.311187,MA0117.1;0.992087,MA0119.1;0.40661,MA0122.1;1.01209,MA0124.1;1.21735,MA0125.1;1.14291,MA0130.1;0,MA0131.1;0.735438,MA0132.1;0,MA0133.1;0,MA0135.1;1.05845,MA0136.1;0.600242,MA0139.1;0.585936,MA0140.1;0.568252,MA0141.1;0.368264,MA0142.1;0.814115,MA0143.1;0.665982,MA0144.1;0.262477,MA0145.1;0.0910975,MA0146.1;1.57153,MA0147.1;0.274511,MA0148.1;0.49752,MA0149.1;0.411562,MA0062.2;0.167299,MA0035.2;0.573016,MA0039.2;0.219063,MA0138.2;0.727395,MA0002.2;0.592533,MA0137.2;0.365364,MA0104.2;0.218974,MA0047.2;0.626803,MA0112.2;1.5617,MA0065.2;0.305574,MA0150.1;0.465855,MA0151.1;0,MA0152.1;0.626912,MA0153.1;1.07519,MA0154.1;0.397336,MA0155.1;0.336768,MA0156.1;0.356017,MA0157.1;0.781683,MA0158.1;0,MA0159.1;1.4173,MA0160.1;1.25065,MA0161.1;0,MA0162.1;0.127623,MA0163.1;0.28052,MA0164.1;0.600609,MA0080.2;0.343316,MA0018.2;0.610433,MA0099.2;0.721008,MA0079.2;0.0190804,MA0102.2;1.65195,MA0258.1;0.688848,MA0259.1;0.26402,MA0442.1;0
}}

Latest revision as of 16:21, 17 September 2013


Phase1 CAGE Peaks

 Short description
Mm9::chr11:55220048..55220060,+p@chr11:55220048..55220060
+
Mm9::chr7:106495646..106495676,-p@chr7:106495646..106495676
-
Mm9::chr7:106497424..106497441,+p@chr7:106497424..106497441
+
Mm9::chr7:106497508..106497559,-p@chr7:106497508..106497559
-
Mm9::chr7:106497588..106497613,-p@chr7:106497588..106497613
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Mm9::chr7:106497675..106497687,-p@chr7:106497675..106497687
-
Mm9::chr7:86293928..86293948,-p2@Mfge8


Enriched pathways on this co-expression cluster<b>Summary:</b><br>Canonical pathway gene sets were compiled from Reactome, Wikipathways and KEGG. For the major signaling pathways, the transcriptionally-regulated genes (downstream targets) were obtained from Netpath. Combined, the canonical pathways and downstream targets totaled 489 human gene sets. The corresponding M. musculus gene sets were inferred by homology using the HomoloGene database. Enrichment for each of the canonical 489 pathways and gene sets included in the co-expression cluster was assessed by the hypergeometric probability. The resulting P values were also then adjusted by the Benjamini-Hochberg method for multiple comparisons.<br><b>Analyst: </b>Emmanuel Dimont<br><br>link to source dataset<br>data

GO IDGO nameFDR corrected p-value
GO:0008429phosphatidylethanolamine binding0.0111756326709401
GO:0001786phosphatidylserine binding0.0111756326709401
GO:0006910phagocytosis, recognition0.0198607156030382
GO:0006911phagocytosis, engulfment0.0198607156030382
GO:0050766positive regulation of phagocytosis0.0198607156030382
GO:0050764regulation of phagocytosis0.0198607156030382
GO:0045807positive regulation of endocytosis0.0204779951512838
GO:0005178integrin binding0.0204779951512838
GO:0009408response to heat0.0206689683680001
GO:0051050positive regulation of transport0.0206689683680001
GO:0030100regulation of endocytosis0.0206689683680001
GO:0006909phagocytosis0.0206689683680001
GO:0007338single fertilization0.0206689683680001
GO:0008037cell recognition0.0206689683680001
GO:0009266response to temperature stimulus0.0206689683680001
GO:0009566fertilization0.0206689683680001
GO:0032403protein complex binding0.0206689683680001
GO:0019897extrinsic to plasma membrane0.0206689683680001
GO:0051082unfolded protein binding0.0227091238159021
GO:0019898extrinsic to membrane0.025657479305141
GO:0051049regulation of transport0.0297355554952831
GO:0004867serine-type endopeptidase inhibitor activity0.034112378156982
GO:0005615extracellular space0.0344229673627489
GO:0044421extracellular region part0.0370600414302398
GO:0009897external side of plasma membrane0.0401296360079547
GO:0004866endopeptidase inhibitor activity0.0401296360079547
GO:0030414protease inhibitor activity0.0401296360079547
GO:0010324membrane invagination0.0415337643679454
GO:0006897endocytosis0.0415337643679454
GO:0009628response to abiotic stimulus0.0415337643679454
GO:0009986cell surface0.0442405047433432
GO:0005543phospholipid binding0.0448897475434736
GO:0022414reproductive process0.0448897475434736
GO:0004857enzyme inhibitor activity0.0448897475434736
GO:0016044membrane organization and biogenesis0.0492860006314063



Relative expression of the co-expression cluster over median <br>Analyst:




Enriched sample ontology terms on this co-expression cluster<b>Summary:</b>To summarize promoter activities (expression profile of a TSS region) across ~1000 samples, we performed enrichment analysis based on FANTOM5 Sample Ontology (FF ontology). The question here is “in which type of samples the promoter is more active”. To answer this question, we compared expressions (TPMs) in the samples associated with a sample ontology term and the rest of the samples by using the Mann-Whitney rank sum test. To summarize ontologies enriched in this co-expression cluster, we ran the same analysis on an averaged expression profile of all promoters that make up. <b>Analyst:</b> Hideya Kawaji <br><br>links to source dataset<br><br>cell_data<br><br><br>


TFBS overrepresentation<b>Summary:</b>The values shown are the p-values for overrepresentation of the motif in this coexpression cluster. So a small p-value means a strong overrepresentation. <b>Analyst:</b> Michiel de Hoon <br><br>link to source data <br> Novel motifs <br>data <br><br> Jaspar motifs <br>data

Novel motifs




JASPAR motifs


Motifs-log10(p-value)
MA0003.10.0861444
MA0004.10.481116
MA0006.10.311391
MA0007.10.465969
MA0009.10.92425
MA0014.10.0886247
MA0017.10.89657
MA0019.10.740036
MA0024.10.880057
MA0025.11.15921
MA0027.12.57545
MA0028.10.321735
MA0029.10.858105
MA0030.10.864739
MA0031.10.828781
MA0038.10.62758
MA0040.10.936879
MA0041.10.404721
MA0042.10.391504
MA0043.11.02178
MA0046.10.960497
MA0048.12.54841
MA0050.10.520357
MA0051.10.636645
MA0052.10.945011
MA0055.10.0406078
MA0056.10
MA0057.10.117936
MA0058.10.384683
MA0059.11.02718
MA0060.10.232592
MA0061.10.261749
MA0063.10
MA0066.10.616444
MA0067.11.27078
MA0068.10.771749
MA0069.10.945354
MA0070.10.93557
MA0071.11.29103
MA0072.10.927016
MA0073.10.00782298
MA0074.10.580087
MA0076.10.356883
MA0077.10.905143
MA0078.10.670113
MA0081.10.420276
MA0083.11.02098
MA0084.11.59945
MA0087.10.977537
MA0088.10.598004
MA0089.10
MA0090.10.446539
MA0091.10.494398
MA0092.10.446857
MA0093.10.879104
MA0095.10
MA0098.10
MA0100.10.568369
MA0101.10.406019
MA0103.10.348572
MA0105.10.488671
MA0106.10.677988
MA0107.10.342432
MA0108.20.763162
MA0109.10
MA0111.10.460823
MA0113.10.649407
MA0114.12.04376
MA0115.11.0246
MA0116.10.311187
MA0117.10.992087
MA0119.10.40661
MA0122.11.01209
MA0124.11.21735
MA0125.11.14291
MA0130.10
MA0131.10.735438
MA0132.10
MA0133.10
MA0135.11.05845
MA0136.10.600242
MA0139.10.585936
MA0140.10.568252
MA0141.10.368264
MA0142.10.814115
MA0143.10.665982
MA0144.10.262477
MA0145.10.0910975
MA0146.11.57153
MA0147.10.274511
MA0148.10.49752
MA0149.10.411562
MA0062.20.167299
MA0035.20.573016
MA0039.20.219063
MA0138.20.727395
MA0002.20.592533
MA0137.20.365364
MA0104.20.218974
MA0047.20.626803
MA0112.21.5617
MA0065.20.305574
MA0150.10.465855
MA0151.10
MA0152.10.626912
MA0153.11.07519
MA0154.10.397336
MA0155.10.336768
MA0156.10.356017
MA0157.10.781683
MA0158.10
MA0159.11.4173
MA0160.11.25065
MA0161.10
MA0162.10.127623
MA0163.10.28052
MA0164.10.600609
MA0080.20.343316
MA0018.20.610433
MA0099.20.721008
MA0079.20.0190804
MA0102.21.65195
MA0258.10.688848
MA0259.10.26402
MA0442.10
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